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https://www.readbyqxmd.com/read/29656287/respiratory-management-of-extremely-preterm-infants-an-international-survey
#1
Marc Beltempo, Tetsuya Isayama, Máximo Vento, Kei Lui, Satoshi Kusuda, Liisa Lehtonen, Gunnar Sjörs, Stellan Håkansson, Mark Adams, Akihiko Noguchi, Brian Reichman, Brian A Darlow, Naho Morisaki, Dirk Bassler, Simone Pratesi, Shoo K Lee, Abhay Lodha, Neena Modi, Kjell Helenius, Prakesh S Shah
BACKGROUND: There are significant international variations in chronic lung disease rates among very preterm infants yet there is little data on international variations in respiratory strategies. OBJECTIVE: To evaluate practice variations in the respiratory management of extremely preterm infants born at < 29 weeks' gestational age (GA) among 10 neonatal networks participating in the International Network for Evaluating Outcomes (iNeo) of Neonates collaboration...
April 13, 2018: Neonatology
https://www.readbyqxmd.com/read/29656181/elevated-systemic-microbial-translocation-in-pregnant-hiv-infected-women-compared-to-hiv-uninfected-women-and-its-inverse-correlations-with-plasma-progesterone-levels
#2
Zejun Zhou, Anna Maya Powell, Vishwanathan Ramakrishnan, Allison Eckard, Carol Wagner, Wei Jiang
In HIV infection, increased adverse perinatal outcomes reported among HIV-associated pregnancies are not fully understood. Currently, microbial product translocation (MT) from a permeable mucosa is demonstrated as a driver of inflammation, and may contribute to preterm delivery in HIV. Here, our results showed that plasma LPS levels (a representative marker of MT) were increased in HIV-infected women in the first and second trimester. Progesterone levels were significantly decreased in HIV-infected subjects in the first trimester and second trimester...
April 10, 2018: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/29656070/-is-universal-first-trimester-screening-for-high-risk-of-preterm-preeclampsia-clinically-meaningful
#3
EDITORIAL
L Sentilhes, E Azria, T Schmitz
No abstract text is available yet for this article.
April 11, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29655847/maternal-air-pollution-exposure-and-preterm-birth-in-wuxi-china-effect-modification-by-maternal-age
#4
Yingying Han, Panhua Jiang, Tianyu Dong, Xinliang Ding, Ting Chen, Gro Dehli Villanger, Heidi Aase, Lu Huang, Yankai Xia
BACKGROUND: Numerous studies have investigated prenatal air pollution and shown that air pollutants have adverse effect on birth outcomes. However, which trimester was the most sensitive and whether the effect was related to maternal age is still ambiguous. OBJECTIVES: This study aims to explore the association between maternal air pollution exposure during pregnancy and preterm birth, and if this relationship is modified by maternal age. METHODS: In this retrospective cohort study, we examine the causal relationship of prenatal exposure to air pollutants including particulate matters, which are less than 10 µm (PM10 ), and ozone (O3 ), which is one of the gaseous pollutants, on preterm birth by gestational age...
April 12, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29653452/the-impact-of-hypoxemia-on-the-development-of-retinopathy-of-prematurity-in-infants-less-than-29-weeks-of-gestation
#5
Narges Afshar, Ronald J Baier, Mohamed Tagin, Cecilia de Cabo, John Minski, Yasser N Elsayed
OBJECTIVE:  To study the impact of cumulative exposure to hypoxemia on the development of retinopathy of prematurity (ROP) in preterm infants less than 29 weeks' gestation. STUDY DESIGN:  This is a retrospective analysis of the effect of cumulative exposure to hypoxemia during the first 10 weeks of life in preterm infants <29 weeks' gestation. Cumulative time spent at various levels of oxygen saturation was calculated by converting the daily percentage of time to minutes per day...
April 13, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29653068/variation-in-birth-outcomes-by-mother-s-country-of-birth-among-hispanic-women-in-the-united-states-2013
#6
Carla L DeSisto, Jill A McDonald
OBJECTIVES: Despite knowledge that the Hispanic population is growing in the United States and that birth outcomes may vary by maternal country of birth, data on birth outcomes by maternal country of birth among Hispanic women are scant. We compared the rates of 3 birth outcomes for infants born in the United States-preterm birth, low birth weight, and small for gestational age-between foreign-born Hispanic women and US-born Hispanic women, and then we examined these birth outcomes by mother's country of birth for foreign-born Hispanic women...
January 1, 2018: Public Health Reports
https://www.readbyqxmd.com/read/29652025/chronic-periodontitis-prevalence-and-the-inflammatory-burden-in-a-sample-population-from-south-india
#7
S K Balaji, Vamsi Lavu, Suresh Rao
Context: Periodontal diseases are among the most prevalent oral diseases in the world. Apart from repercussions in the oral cavity, there is evidence that periodontitis contributes to systemic damage in chronic diseases such as cardiovascular disease, diabetes, and preterm low birth weight. Aims: The aims of this study were to estimate the prevalence of chronic periodontitis in a sample urban population (<18 years) in Tamil Nadu and to estimate the inflammatory burden posed by chronic periodontitis by calculating the periodontal inflammatory surface area...
March 2018: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/29651319/effects-of-perinatal-factors-on-body-mass-index-and-physical-fitness-of-school-age-children
#8
Miha Lucovnik, Gregor Starc, Petra Golja, Ivan Verdenik, Irena Stucin Gantar
Objective: To examine the effects of various maternal and neonatal perinatal factors on the child's body mass index (BMI) and physical fitness at school-age. Methods: Data from two registries, the SLOfit database (a national surveillance system of children's motor and physical development) and Slovenian National Perinatal Information System (NPIS) were analysed. Perinatal data for 2,929 children born in 2008 were linked to results of SLOfit testing of these children in 2016...
June 2018: Zdravstveno Varstvo
https://www.readbyqxmd.com/read/29651255/sex-specific-skeletal-muscle-fatigability-and-decreased-mitochondrial-oxidative-capacity-in-adult-rats-exposed-to-postnatal-hyperoxia
#9
Laura H Tetri, Gary M Diffee, Gregory P Barton, Rudolf K Braun, Hannah E Yoder, Kristin Haraldsdottir, Marlowe W Eldridge, Kara N Goss
Premature birth affects more than 10% of live births, and is characterized by relative hyperoxia exposure in an immature host. Long-term consequences of preterm birth include decreased aerobic capacity, decreased muscular strength and endurance, and increased prevalence of metabolic diseases such as type 2 diabetes mellitus. Postnatal hyperoxia exposure in rodents is a well-established model of chronic lung disease of prematurity, and also recapitulates the pulmonary vascular, cardiovascular, and renal phenotype of premature birth...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29650428/-extrauterine-growth-restriction-among-neonates-with-a-birthweight-less-than-1-500grams
#10
Alejandro Avila-Alvarez, Alfonso Solar Boga, Carmen Bermúdez-Hormigo, Jesús Fuentes Carballal
INTRODUCTION: Growth restriction in preterm infants has been related to a poor neurodevelopment outcome. OBJECTIVES: To define the incidence of postnatal growth restriction in premature babies ≤1,500 grams and to detect related clinical or biochemical markers. METHODS: Retrospective longitudinal observational study. Multivariate linear regression models were used to determine variables that can predict the change in weight z-score during admission...
April 9, 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29650414/joint-laxity-in-preschool-children-born-preterm
#11
Domenico M Romeo, Chiara Velli, Simona Lucibello, Gloria Ferrantini, Giuseppina Leo, Claudia Brogna, Francesco Cota, Daniela Ricci, Francesca Gallini, Costantino Romagnoli, Giovanni Vento, Eugenio Mercuri
OBJECTIVE: To evaluate the prevalence of joint laxity in children born preterm assessed in the first 2 years, the relationship between joint laxity and motor performance at preschool age, and possible changes over time in a subgroup of children followed longitudinally. STUDY DESIGN: The revised scale of Beighton Score was used to evaluate joint laxity in a population of 132 preschool children born preterm between 24 and 32 weeks of gestational age. All were assessed for joint laxity between 12 and 24 months of age...
April 9, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29649918/the-impact-of-unicornuate-uterus-on-perinatal-outcomes-after-ivf-icsi-cycles-a-matched-retrospective-cohort-study
#12
Xinxia Chen, Peihao Liu, Yan Sheng, Weiping Li, Rong Tang, Lingling Ding, Yingying Qin, Zi-Jiang Chen
OBJECTIVE: To evaluate the impact of unicornuate uterus on perinatal outcomes after in vitro fertilization and/or intracytoplasmic sperm injection (IVF/ICSI) cycles. METHODS: We performed a retrospective cohort study including 160 women with unicornuate uterus and 1:1 matched controls with normally shaped uterus. They received IVF/ICSI treatment during January 2009 and December 2011. The perinatal outcomes were followed up till December 2014. RESULTS: There were no significant differences in pregnancy rate, clinical pregnancy rate or live birth rate (53...
April 12, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29649829/relation-of-retinopathy-of-prematurity-to-brain-volumes-at-term-equivalent-age-and-developmental-outcome-at-2-years-of-corrected-age-in-very-preterm-infants
#13
Kristbjörg Sveinsdóttir, David Ley, Holger Hövel, Vineta Fellman, Petra S Hüppi, Lois E H Smith, Ann Hellström, Ingrid Hansen Pupp
BACKGROUND: Retinopathy of prematurity (ROP) is a major complication of preterm birth and has been associated with later visual and nonvisual impairments. OBJECTIVES: To evaluate relationships between any stage of ROP, brain volumes, and developmental outcomes. METHODS: This study included 52 very preterm infants (gestational age [mean ± SD]: 26.4 ± 1.9 weeks). Total brain, gray matter, unmyelinated white matter (UWMV), and cerebellar volumes were estimated in 51 out of 52 infants by magnetic resonance imaging at term-equivalent age...
April 12, 2018: Neonatology
https://www.readbyqxmd.com/read/29649818/the-risk-of-human-papillomavirus-infection-for-spontaneous-abortion-spontaneous-preterm-birth-and-pregnancy-rate-of-assisted-reproductive-technologies-a-systematic-review-and-meta-analysis
#14
Yi-Quan Xiong, Yun Mo, Qiao-Ming Luo, Shu-Ting Huo, Wen-Qiao He, Qing Chen
AIMS: To estimate the impact of human papillomavirus (HPV) infection on spontaneous abortion, spontaneous preterm birth (sPTB), pregnancy rate of females undergoing assisted reproductive technologies (ART), and spontaneous abortion of ART pregnancy. METHODS: PubMed, Medline, Embase, and the Cochrane Library were searched until December 16, 2016. The OR or relative risk (RR) with its corresponding 95% CI were selected as effect size. Subgroup analysis of HPV genotype infection (high-risk HPV [HR-HPV] or indiscriminate genotype) was performed...
April 12, 2018: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/29649318/confined-placental-mosaicism-revisited-impact-on-pregnancy-characteristics-and-outcome
#15
Jérôme Toutain, Damien Goutte-Gattat, Jacques Horovitz, Robert Saura
OBJECTIVES: We wanted to re-evaluate the influence of confined placental mosaicism subtypes (type 2 and type 3) on pregnancy characteristics and outcome. MATERIAL AND METHODS: From July 2009 to December 2015, 5512 chorionic villus samplings were performed in our Fetal Medicine Center. Conventional karyotyping was performed after long-term and short-term cultured villi to define type 2 or type 3 confined placental mosaicisms. Karyotype after amniocentesis was performed to exclude true fetal mosaicism, when appropriate...
2018: PloS One
https://www.readbyqxmd.com/read/29649290/the-contribution-of-gestational-age-area-deprivation-and-mother-s-country-of-birth-to-ethnic-variations-in-infant-mortality-in-england-and-wales-a-national-cohort-study-using-routinely-collected-data
#16
Yangmei Li, Maria A Quigley, Nirupa Dattani, Ron Gray, Hiranthi Jayaweera, Jennifer J Kurinczuk, Alison Macfarlane, Jennifer Hollowell
OBJECTIVES: We aimed to describe ethnic variations in infant mortality and explore the contribution of area deprivation, mother's country of birth, and prematurity to these variations. METHODS: We analyzed routine birth and death data on singleton live births (gestational age≥22 weeks) in England and Wales, 2006-2012. Infant mortality by ethnic group was analyzed using logistic regression with adjustment for sociodemographic characteristics and gestational age...
2018: PloS One
https://www.readbyqxmd.com/read/29649108/postnatal-growth-disadvantage-of-the-small-for-gestational-age-preterm-twins
#17
Iris Morag, Orly Stern Levkovitz, Maya Siman-Tov, Mor Frisch, Orit Pinhas-Hamiel, Tzipi Strauss
In this study, we examined early growth characteristics among small-for-gestational-age (SGA) preterm twins compared to their appropriate-for-gestational-age (AGA) counterparts. A retrospective study evaluated all consecutive twins born between 2008 and 2015 at a tertiary referral center whose gestational age ranged from 30.0 to 34.86 weeks. Included were twins in which one twin was AGA and the other SGA at birth. Changes of ≥2, 1-1.99, and 0-0.99 in z-score between births and 36 weeks post menstrual age (PMA) were respectively defined as severe, moderate, and mild postnatal growth failure (PNGF) in weight or head circumference (HC)...
April 12, 2018: Nutrients
https://www.readbyqxmd.com/read/29649028/does-the-incidence-of-postoperative-complications-after-inguinal-hernia-repair-justify-hospital-admission-in-prematurely-and-term-born-infants
#18
Marina Massoud, A Y Rosalie Kühlmann, Monique van Dijk, Lonneke M Staals, Rene M H Wijnen, Joost van Rosmalen, Cornelius E J Sloots, Claudia M G Keyzer-Dekker
BACKGROUND: Postoperatively, young infants are admitted overnight in view of the risk for respiratory complications such as desaturation and apnea. This risk seems much lower than previously reported. Until what age this risk persists, and which infants might actually qualify for day-care treatment, is unknown. METHODS: We retrospectively reviewed medical charts from preterm infants <45 weeks postconceptional age (PCA), 45-60 weeks PCA, and term infants <3 months admitted overnight after inguinal hernia repair, from January 2011 to December 2015 in a large tertiary children's hospital...
April 11, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29648694/safety-of-nifedipine-in-threatened-preterm-labor-investigation-by-three-dimensional-echocardiography
#19
Leonti Grin, Avishag Laish-Farkash, Simon Shenhav, Xavier Piltz, Liah Ganelin, Mark Rabinovich, Eyal Y Anteby, Chaim Yosefy
OBJECTIVE: To evaluate atrial and ventricular parameters using real time three-dimensional transthoracic echocardiography (RT3DTTE) in women treated with nifedipine in the early third trimester (III-T) of pregnancy. METHODS: A prospective single-subject design study in a university-affiliated hospital, where each participant served as her own control. We studied 25 pregnant women at a gestational age of 25-33 weeks with TPTL prior to vs 48 hours postnifedipine treatment...
April 12, 2018: Echocardiography
https://www.readbyqxmd.com/read/29644893/activation-of-the-nfkb-pathway-alters-the-phenotype-of-mscs-in-the-tracheal-aspirates-of-preterm-infants-with-severe-bpd
#20
Tobias Reicherzer, Susanne Häffner, Tayyab Shahzad, Judith Gronbach, Josef Mysliwietz, Christoph Huebener, Uwe Hasbargen, Jan Gertheiss, Andreas Schulze, Saverio Bellusci, Rory E Morty, Anne Hilgendorff, Harald Ehrhardt
Mesenchymal stromal cells (MSCs) are released into the airways of preterm infants following lung injury. These cells display a pro-inflammatory phenotype and are associated with development of severe bronchopulmonary dysplasia (BPD). We aimed to characterize the functional properties of MSCs obtained from tracheal aspirates of 50 preterm infants who required invasive ventilation. Samples were separated by disease severity. The increased proliferative capacity of MSCs was associated with longer duration of mechanical ventilation and higher severity of BPD...
April 12, 2018: American Journal of Physiology. Lung Cellular and Molecular Physiology
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