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https://www.readbyqxmd.com/read/28616477/is-there-a-lyme-like-disease-in-australia-summary-of-the-findings-to-date
#1
REVIEW
Melissa Judith Chalada, John Stenos, Richard Stewart Bradbury
Lyme Borreliosis is a common tick-borne disease of the northern hemisphere caused by the spirochaetes of the Borrelia burgdorferi sensu lato (B. burgdorferi s. l.) complex. It results in multi-organ disease with arthritic, cardiac, neurological and dermatological manifestations. In the last twenty-five years there have been over 500 reports of an Australian Lyme-like syndrome in the scientific literature. However, the diagnoses of Lyme Borreliosis made in these cases have been primarily by clinical presentation and laboratory results of tentative reliability and the true cause of these illnesses remains unknown...
December 2016: One Health
https://www.readbyqxmd.com/read/28612350/blood-donor-borrelia-burgdorferi-sensu-lato-seroprevalence-and-history-of-tick-bites-at-a-northern-limit-of-the-vector-distribution
#2
Dag Hvidsten, Liisa Mortensen, Bjørn Straume, Mirjana Grujic Arsenovic, Anne-Berit Pedersen, Gro Lyngås, Jeremy S Gray, Nils Grude
In order to study the antibody seroprevalence of the causal agent of Lyme borreliosis, Borrelia burgdorferi sensu lato (s.l.), and the history of tick bites at a geographical distribution limit of Ixodes ricinus, we compared healthy blood donors in geographically extreme regions: the borreliosis-endemic Vestfold County (59°N) and the region of northern Norway. Blood samples were screened using IgG/VlsE ELISA, and positive/borderline samples were confirmed using C6 ELISA and immunoblot assays. Also, donors completed a questionnaire consisting of several items including the places they have lived, and whether they owned any pets...
June 14, 2017: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/28608042/-granulomatous-reaction-pattern-of-the-skin-interstitial-granulomatous-dermatitis-lymphoma-vasculitis
#3
REVIEW
C Rose, K Holl-Ulrich
A particular diagnostic situation in the classification of a granulomatous dermatitis results when no circumscribed granulomas but instead a diffuse interstitial histiocytic inflammatory infiltrate, a granulomatous vasculitis or a neoplastic lymphocytic infiltrate is found. Interstitial granulomatous dermatitis was originally described in patients with arthritis. Later, it was recognized that there are also associations with other usually immunological diseases. Differentiating between interstitial granulomatous dermatitis and the interstitial form of granuloma annulare, early morphea and variants of borreliosis or scleromyxedema as well as interstitial granulomatous drug reaction can be very difficult...
June 12, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28583197/no-evidence-of-borrelia-mayonii-in-an-endemic-area-for-lyme-borreliosis-in-france
#4
Pierre H Boyer, Sylvie J De Martino, Yves Hansmann, Laurence Zilliox, Nathalie Boulanger, Benoît Jaulhac
BACKGROUND: Borrelia mayonii is currently the latest species belonging to the Borrelia burgdorferi (sensu lato) complex to be discovered. Interestingly it is involved in human pathology causing a high fever. We looked for its presence in post- tick bite febrile patients as well as in Ixodes ricinus ticks in an endemic area of France. RESULTS: After ensuring that our molecular technics correctly detected B. mayonii, 575 patients and 3,122 Ixodes ricinus nymphs were tested...
June 5, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28579253/molecular-evidence-of-borrelia-burgdorferi-sensu-lato-in-patients-in-brazilian-central-western-region
#5
Fernando Aguilar Lopes, Jania de Rezende, Danielly Beraldo Dos Santos Silva, Fernanda de Cássia Gonçalves Alves, Carina Elisei de Oliveira, Izaías Pereira da Costa
We aimed to detect DNA of Borrelia burgdorferi in whole blood and serum samples of patients with clinical symptoms and epidemiology compatible with Brazilian Lyme-like disease. Four patients with positive epidemiological histories were recruited for the study. Blood samples were collected, screened by serologic testing by ELISA and Western blotting and molecular identification of B. burgdorferi by amplifying a fragment of the conserved gene that synthesizes the hook flagellar flgE. The results showed positive serology and for the first time, the presence of B...
June 2, 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28558786/lost-in-plasmids-next-generation-sequencing-and-the-complex-genome-of-the-tick-borne-pathogen-borrelia-burgdorferi
#6
G Margos, S Hepner, C Mang, D Marosevic, S E Reynolds, S Krebs, A Sing, M Derdakova, M A Reiter, V Fingerle
BACKGROUND: Borrelia (B.) burgdorferi sensu lato, including the tick-transmitted agents of human Lyme borreliosis, have particularly complex genomes, consisting of a linear main chromosome and numerous linear and circular plasmids. The number and structure of plasmids is variable even in strains within a single genospecies. Genes on these plasmids are known to play essential roles in virulence and pathogenicity as well as host and vector associations. For this reason, it is essential to explore methods for rapid and reliable characterisation of molecular level changes on plasmids...
May 30, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28550059/europe-wide-meta-analysis-of-borrelia-burgdorferi-sensu-lato-prevalence-in-questing-ixodes-ricinus-ticks
#7
Martin Strnad, Václav Hönig, Daniel Růžek, Libor Grubhoffer, Ryan O M Rego
Lyme borreliosis is the most common zoonotic disease transmitted by ticks in Europe and North America. Despite having multiple tick vectors, the causative agent Borrelia burgdorferi sensu lato, is vectored mainly by Ixodes ricinus in Europe. In the present study, we aimed to review and summarize the existing data published from 2010 to 2016 concerning the prevalence of B. burgdorferi s.l. spirochetes in questing I. ricinus The primary focus was to evaluate the infection rate of these bacteria in ticks, accounting for tick stage, adult tick gender, region and detection method, as well as to investigate any changes in prevalence over time...
May 26, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28549720/infection-with-borrelia-chilensis-in-ixodes-stilesi-ticks-collected-from-pudu-puda-deer
#8
Claudio Verdugo, Omar Jiménez, Carlos Hernández, Pedro Álvarez, Angelo Espinoza, Daniel González-Acuña
Lyme borreliosis is a vector-borne zoonosis caused by Borrelia burgdorferi sensu lato species complex spirochetes, which are maintained in transmission cycles among vertebrates and Ixodes ticks. Recently, a new genospecies within this complex, Borrelia chilensis, was described in Ixodes stilesi collected from the environment and from rodents in Chile. This tick also infests the native Southern pudu deer (Pudu puda). The objectives of this study were to investigate the prevalence, intensity of infestation, and aggregation of hard ticks on this deer species, and to determine the presence of borrelial pathogens in the ticks...
May 18, 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/28549151/borrelia-species-detected-in-ticks-feeding-on-wild-korean-water-deer-hydropotes-inermis-using-molecular-and-genotypic-analyses
#9
D VanBik, S H Lee, M G Seo, B R Jeon, Y K Goo, S J Park, M H Rhee, O D Kwon, T H Kim, P J L Geraldino, D Kwak
Lyme borreliosis is a vector-borne disease transmitted through the bite of ticks infected by Borrelia burgdorferi sensu lato group, including B. burgdorferi sensu stricto, B. afzelii, and B. garinii. The goal of the present study was to detect Borrelia species in ticks infesting wild Korean water deer (KWD; Hydropotes inermis Swinhoe), using molecular and genotypic analyses. In total, 48 ticks were collected from KWD, all of which were morphologically identified as Haemaphysalis longicornis Neumann that is dominant in Korea...
May 26, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/28545520/the-abundance-of-the-lyme-disease-pathogen-borrelia-afzelii-declines-over-time-in-the-tick-vector-ixodes-ricinus
#10
Maxime Jacquet, Dolores Genné, Alessandro Belli, Elodie Maluenda, Anouk Sarr, Maarten J Voordouw
BACKGROUND: The population dynamics of vector-borne pathogens inside the arthropod vector can have important consequences for vector-to-host transmission. Tick-borne spirochete bacteria of the Borrelia burgdorferi (sensu lato) species complex cause Lyme borreliosis in humans and spend long periods of time (>12 months) in their Ixodes tick vectors. To date, few studies have investigated the dynamics of Borrelia spirochete populations in unfed Ixodes nymphal ticks. METHODS: Larval ticks from our laboratory colony of I...
May 25, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28539197/candidatus-neoehrlichia-mikurensis-and-borrelia-burgdorferi-sensu-lato-detected-in-the-blood-of-norwegian-patients-with-erythema-migrans
#11
H Quarsten, A Grankvist, L Høyvoll, I B Myre, T Skarpaas, V Kjelland, C Wenneras, S Noraas
The most common tick-borne human disease in Norway is Lyme borreliosis. Ticks in Norway also harbour less known disease-causing agents such as Candidatus Neoehrlichia mikurensis, Borrelia miyamotoi and Rickettsia helvetica. However, human infections caused by these pathogens have never been described in Norway. The main aims of the study were to evaluate the contribution of several tick-borne bacterial agents, other than Borrelia burgdorferi sensu lato, to zoonotic diseases in Norway and to determine their clinical pictures...
May 13, 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/28532987/hints-of-lyme-disseminated-borreliosis-involving-the-mitral-and-tricuspid-valves
#12
Ankit Maheshwari, Robert J Bache
No abstract text is available yet for this article.
May 19, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28528880/lyme-borreliae-prevalence-and-genospecies-distribution-in-ticks-removed-from-humans
#13
Patrick Waindok, Sabine Schicht, Volker Fingerle, Christina Strube
Lyme borreliosis (LB) is the most important human tick-borne disease, but Borrelia genospecies cause different clinical manifestations. Ticks of the genus Ixodes removed from humans between 2006 and 2012 were analysed for Borrelia burgdorferi sensu lato (sl) infections. The majority of ticks originated from the Greater Hanover region in Northern Germany. The engorgement status varied over the entire spectrum from unengorged (no evidence of started blood feeding) to fully engorged. In the present study, prevalence data for B...
May 13, 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/28526093/canine-infection-with-borrelia-burgdorferi-dirofilaria-immitis-anaplasma-spp-and-ehrlichia-spp-in-canada-2013-2014
#14
Brian H Herrin, Andrew S Peregrine, Jonas Goring, Melissa J Beall, Susan E Little
BACKGROUND: Canine test results generated by veterinarians throughout Canada from 2013-2014 were evaluated to assess the geographical distribution of canine infection with Borrelia burgdorferi, Dirofilaria immitis, Ehrlichia spp., and Anaplasma spp. METHODS: The percent positive test results of 115,636 SNAP® 4Dx® Plus tests from dogs tested were collated by province and municipality to determine the distribution of these vector-borne infections in Canada. RESULTS: A total of 2,844/115,636 (2...
May 19, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28477365/a-foot-tumor-as-late-cutaneous-lyme-borreliosis-a-new-entity
#15
O Bauvin, J L Schmutz, T Busato, B Cribier, A Barbaud, D Wahl, A C Bursztejn
Acrodermatitis Chronica Atrophicans (ACA) is the late cutaneous form of Lyme borreliosis. It is a rare tertiary manifestation characterized by a slowly progressive course over many weeks to months. The early inflammatory phase manifests with a bluish-red discoloration and doughy swelling of the skin. Atrophic phase represents a late-phase process with red discoloration, thin and wrinkled appearance to the skin. We present a patient who exhibited a previously non-described form of late cutaneous Lyme borreliosis (LCLB) with a foot tumor...
May 6, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28475032/molecular-characterization-of-candidatus-borrelia-tachyglossi-family-spirochaetaceae-in-echidna-ticks-bothriocroton-concolor
#16
Siew-May Loh, Amber Gillett, Una Ryan, Peter Irwin, Charlotte Oskam
Recently, a novel species of the genus Borreliawas identified in Bothriocroton concolor and Ixodes holocyclus ticks from echidnas. Analyses of 16S rRNA and flaB genes identified three closely related genotypes of this bacterium (Borrelia sp. Aus A-C) that were unique and distinct from previously described borreliae. Phylogenetic analyses of flaB (763 bp), groEL (1537 bp), gyrB (1702 bp) and glpQ (874 bp) gene sequences and concatenated sequences (3585 bp) of three gene loci (16S rRNA, flaB and gyrB) were consistent with previous findings and confirm that this novel species of the genus Borrelia is more closely related to, yet distinct from, the Reptile-associated (REP) and Relapsing Fever (RF) groups...
April 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28473022/-clinical-manifestations-diagnosis-and-treatment-of-lyme-borreliosis
#17
Lukas Frans Ocias, Bo Bødker Jensen, Fredrikke Christie Knudtzen, Sigurdur Skarphedinsson, Ram Benny Dessau
Lyme borreliosis is an infection caused by the Borrelia burgdorferi sensu lato complex and transmitted by Ixodes ricinus ticks in Denmark. It can manifest itself in several different forms of which erythema migrans is the most common and is diagnosed by clinical assessment of the characteristic erythema. Laboratory support for the clinical diagnosis of other manifestations rests on the measurement of Borrelia-specific antibodies. Treatment is straight-forward with antibiotics such as penicillin. This paper reviews the clinical manifestations, diagnosis and treatment of this infection...
May 1, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28449695/intermediate-uveitis-pattern-of-etiology-complications-treatment-and-outcome-in-a-tertiary-academic-center
#18
Thomas Ness, Daniel Boehringer, Sonja Heinzelmann
BACKGROUND: Patients with intermediate uveitis (IU) represent a heterogenous group characterized by a wide spectrum of etiologies and regional differences. Aim of the study was to analyze the characteristics of patients with IU examined in an academic center in Germany. METHODS: We conducted a retrospective analysis of the clinical records of all patients with intermediate uveitis referred to the Eye Center, University of Freiburg from 2007 to 2014. Diagnosis followed the Standardization in Uveitis Nomenclature (SUN) criteria...
April 27, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28444236/the-cost-of-lyme-borreliosis
#19
Cees C van den Wijngaard, Agnetha Hofhuis, Albert Wong, Margriet G Harms, G Ardine de Wit, Anna K Lugnér, Anita W M Suijkerbuijk, Marie-Josée J Mangen, Wilfrid van Pelt
Lyme borreliosis (LB) is the most frequently reported tick-borne infection in Europe and North America. The aim of this study was to estimate the cost-of-illness of LB in the Netherlands. We used available incidence estimates from 2010 for tick bite consultations and three symptomatic LB outcomes: erythema migrans (EM), disseminated LB and Lyme-related persisting symptoms. The cost was estimated using these incidences and the average cost per patient as derived from a patient questionnaire. We estimated the cost from a societal perspective, including healthcare cost, patient cost and production loss, using the friction cost method and a 4% annual discount rate...
June 1, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/28438912/effects-of-conservation-management-of-landscapes-and-vertebrate-communities-on-lyme-borreliosis-risk-in-the-united-kingdom
#20
REVIEW
Caroline Millins, Lucy Gilbert, Jolyon Medlock, Kayleigh Hansford, Des Ba Thompson, Roman Biek
Landscape change and altered host abundance are major drivers of zoonotic pathogen emergence. Conservation and biodiversity management of landscapes and vertebrate communities can have secondary effects on vector-borne pathogen transmission that are important to assess. Here we review the potential implications of these activities on the risk of Lyme borreliosis in the United Kingdom. Conservation management activities include woodland expansion, management and restoration, deer management, urban greening and the release and culling of non-native species...
June 5, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
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