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https://www.readbyqxmd.com/read/28742855/decreases-in-heart-rate-variability-are-associated-with-postoperative-complications-in-hip-fracture-patients
#1
Gernot Ernst, Leiv Otto Watne, Frede Frihagen, Torgeir Bruun Wyller, Andreas Dominik, Morten Rostrup
BACKGROUND: To explore relevant associations between deviations in linear and nonlinear heart rate variability (HRV) scores, and short-term morbidity and mortality in patients undergoing hip-surgery after a fracture. METHODS: 165 patients with hip fractures being admitted for surgery at two hospitals were included in a prospective cohort study. A short-term ECG was recorded within 24 hours of arrival. 15 patients had to be excluded due to insufficient quality of the ECG recordings...
2017: PloS One
https://www.readbyqxmd.com/read/28742812/broad-range-lytic-bacteriophages-that-kill-staphylococcus-aureus-local-field-strains
#2
Virginia Abatángelo, Natalia Peressutti Bacci, Carina A Boncompain, Ariel A Amadio, Soledad Carrasco, Cristian A Suárez, Héctor R Morbidoni
Staphylococcus aureus is a very successful opportunistic pathogen capable of causing a variety of diseases ranging from mild skin infections to life-threatening sepsis, meningitis and pneumonia. Its ability to display numerous virulence mechanisms matches its skill to display resistance to several antibiotics, including β-lactams, underscoring the fact that new anti-S. aureus drugs are urgently required. In this scenario, the utilization of lytic bacteriophages that kill bacteria in a genus -or even species- specific way, has become an attractive field of study...
2017: PloS One
https://www.readbyqxmd.com/read/28741200/short-and-long-term-outcomes-in-malnourished-patients-after-laparoscopic-or-open-radical-gastrectomy
#3
Hua-Long Zheng, Jun Lu, Chao-Hui Zheng, Ping Li, Jian-Wei Xie, Jia-Bin Wang, Jian-Xian Lin, Qi-Yue Chen, Mi Lin, Ru-Hong Tu, Chang-Ming Huang
OBJECTIVE: The aim of this study was to compare the short- and long-term outcomes of malnourished gastric cancer patients who underwent laparoscopic or open radical gastrectomy. BACKGROUND: Preoperative malnutrition is an independent risk factor for postoperative mortality and morbidity in major gastrointestinal surgery. However, whether laparoscopic surgery can improve the short- and long-term outcomes of malnourished gastric cancer patients has not been determined...
July 24, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28740928/magnetic-resonance-imaging-guided-reirradiation-of-recurrent-and-second-primary-head-and-neck-cancer
#4
Allen M Chen, Minsong Cao, Sophia Hsu, James Lamb, Argin Mikaeilian, Yingli Yang, Nzhde Agazaryan, Daniel A Low, Michael L Steinberg
PURPOSE: To report a single-institutional experience using magnetic resonance imaging (MRI) guided radiation therapy for the reirradiation of recurrent and second cancers of the head and neck. METHODS AND MATERIALS: Between October 2014 and August 2016, 13 consecutive patients with recurrent or new primary cancers of the head and neck that occurred in a previously irradiated field were prospectively enrolled in an institutional registry trial to investigate the feasibility and efficacy of MRI guided radiation therapy using a 0...
April 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/28740682/combined-analgesic-treatment-of-epidural-and-paravertebral-block-after-thoracic-surgery
#5
Yujiro Yokoyama, Takahiro Nakagomi, Daichi Shikata, Taichiro Goto
In pulmonary surgical practice, appropriate pain management after thoracotomy is essential for patient recovery and the prevention of complications. Although epidural analgesia (EPI) has been established for chest surgery, it has some limitations and contraindications. Recently, paravertebral block (PVB) was reported as a good alternative method with fewer side effects. Despite the significant effects of these two treatments, postoperative pain remains among the greatest patient burdens. In our institution, we apply a combination of epidural and PVBs after thoracic surgery to reduce pain more effectively...
June 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28740667/discordance-of-physician-clinical-judgment-vs-pneumonia-severity-index-psi-score-to-admit-patients-with-low-risk-community-acquired-pneumonia-a-prospective-multicenter-study
#6
Pedro J Marcos, Marcos I Restrepo, Francisco J González-Barcala, Nilam J Soni, Iria Vidal, Pilar Sanjuàn, Diego Llinares, Lucía Ferreira-Gonzalez, Carlos Rábade, Isabel Otero-González, Pedro Marcos, Héctor Verea-Hernando
BACKGROUND: The relationship between clinical judgment and the pneumonia severity index (PSI) score in deciding the site of care for patients with community-acquired pneumonia (CAP) has not been well investigated. The objective of the study was to determine the clinical factors that influence decision-making to hospitalize low-risk patients (PSI ≤2) with CAP. METHODS: An observational, prospective, multicenter study of consecutive CAP patients was performed at five hospitals in Spain...
June 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28739224/esbl-producing-escherichia-coli-and-klebsiella-pneumoniae-the-most-prevalent-clinical-isolates-obtained-between-2005-and-2012-in-mexico
#7
Humberto Barrios, Ulises Garza-Ramos, Ilse Mejia-Miranda, Fernando Reyna-Flores, Alejandro Sánchez-Perez, Dalila Mosqueda-García, Jesus Silva-Sanchez
OBJECTIVES: To identify the prevalence of ESBL genes in the principal group of Enterobacteriaceae causing nosocomial infections and to identify the phylogenetic group in E. coli isolates. METHODS: There were collected 1084 ESBL-producing Enterobacteriaceae isolates during 2005 to 2012 from adult patients from 14 hospitals and corresponding to eight states and five regions (SE, S, N, W and NW) in Mexico. The CTX-M-(CTX-M-1 group), SHV-, TLA- and GES-type ESBLs genes were screened...
July 21, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28738944/predicting-postoperative-complications-for-acute-care-surgery-patients-using-the-acs-nsqip-surgical-risk-calculator
#8
Jessica R Burgess, Benjamin Smith, Rebecca Britt, Leonard Weireter, Travis Polk
The American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) risk calculator has been used to assist surgeons in predicting the risk of postoperative complications. This study aims to determine if the risk calculator accurately predicts complications in acute care surgical patients undergoing laparotomy. A retrospective review was performed on all patients on the acute care surgery service at a tertiary hospital who underwent laparotomy between 2011 and 2012. The preoperative risk factors were used to calculate the estimated risks of postoperative complications in both the original ACS NSQIP calculator and updated calculator (June 2016)...
July 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28738733/cases-of-mortality-in-little-penguins-eudyptula-minor-in-new-zealand-associated-with-avian-malaria
#9
D C Sijbranda, S Hunter, L Howe, B Lenting, L Argilla, B D Gartrell
CASE HISTORY: A little penguin (Eudyptula minor) of wild origin, in captivity at Wellington Zoo, became inappetent and lethargic in March 2013. Despite supportive care in the zoo's wildlife hospital, the bird died within 24 hours. CLINICAL FINDINGS: Weight loss, dehydration, pale mucous membranes, weakness, increased respiratory effort and biliverdinuria were apparent on physical examination. Microscopic evaluation of blood smears revealed intra-erythrocytic stages of Plasmodium spp...
July 24, 2017: New Zealand Veterinary Journal
https://www.readbyqxmd.com/read/28738364/risk-factors-for-community-acquired-pneumonia-in-adults-a-systematic-review-of-observational-studies
#10
Jordi Almirall, Mateu Serra-Prat, Ignasi Bolíbar, Valentina Balasso
We performed a systematic review of the literature to establish conclusive evidence of risk factors for community-acquired pneumonia (CAP). Observational studies (cross-sectional, case-control, and cohort studies) the primary outcome of which was to assess risk factors for CAP in both hospitalized and ambulatory adult patients with radiologically confirmed pneumonia were selected. The Newcastle-Ottawa Scale specific for cohort and case-control designs was used for quality assessment. Twenty-nine studies (20 case-control, 8 cohort, and 1 cross-sectional) were selected, with 44...
July 25, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28738348/colistin-resistance-in-kpc-2-and-shv-5-producing-klebsiella-pneumoniae-clinical-isolates-in-bulgaria
#11
Encho Savov, Iva Todorova, Lida Politi, Angelina Trifonova, Maja Borisova, Elena Kioseva, Athanassios Tsakris
BACKGROUND/AIMS: Colistin resistance is increasingly recognized among carbapenemase-producing Klebsiella pneumoniae isolates in several European regions. The current study documents the appearance of colistin resistance among KPC-2 and SHV-5-produning K. pneumoniae strains in Bulgaria. METHODS: Four colistin-resistant K. pneumoniae isolates were recovered from 2 patients hospitalized in the anesthesiology and resuscitation clinic of a tertiary care university hospital in Sofia, Bulgaria...
July 22, 2017: Chemotherapy
https://www.readbyqxmd.com/read/28737622/changes-in-the-nature-and-severity-of-invasive-pneumococcal-disease-in-children-before-and-after-the-7-valent-and-13-valent-pneumococcal-conjugate-vaccine-programs-in-calgary-canada
#12
Leah J Ricketson, Nicholas G Conradi, Otto G Vanderkooi, James D Kellner
BACKGROUND: Since the introduction of childhood pneumococcal conjugate vaccines, invasive pneumococcal disease (IPD) incidence has decreased in children and the predominant serotypes causing disease have changed. This study describes changes in the clinical features of IPD in children (<18 years) before and after conjugate vaccine introduction. METHODS: The Calgary Area Streptococcus pneumoniae Epidemiology Research (CASPER) study collects information on all IPD cases in Calgary, Alberta, Canada...
July 20, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28737025/-influence-of-initial-protocolized-treatment-with-steroids-in-length-of-stay-and-costs-of-community-acquired-pneumonia
#13
J Gómez Gómez, J L Gómez Torres, A Hernández Torres, J A García Córdoba, M Canteras Jordana
OBJECTIVE: The aim of the study was to analyze the impact of steroid treatment in patients with community acquired pneumonia (CAP), both in length of stay and economical cost of admission at a clinical university hospital. METHODS: Prospective study of admitted patients with the diagnosis of CAP, both in Internal Medicine and Infectious diseases department. The study was conducted from January to march 2015; patients receiving steroids from diagnosis to end of antibiotic treatment were classified as group I; otherwise, they were considered in group II...
July 24, 2017: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://www.readbyqxmd.com/read/28736811/incidental-finding-of-a-membranous-interventricular-septum-aneurysm
#14
Konstantinos C Theodoropoulos, Giovanni Masoero, Emily Denman, Alexandros Papachristidis, Mark J Monaghan
We present the case of a 34-year-old female who was admitted to our hospital due to community-acquired pneumonia and had a transthoracic echocardiogram which revealed an aneurysm of the membranous interventricular septum. This was further investigated with a transesophageal echocardiogram which showed in detail the anatomical features of this very rare condition.
July 23, 2017: Echocardiography
https://www.readbyqxmd.com/read/28736021/infectious-complications-and-multidrug-resistant-bacteria-in-patients-with-hematopoietic-stem-cell-transplantation-in-the-first-12-months-after-transplant
#15
A César-Arce, P Volkow-Fernández, L M Valero-Saldaña, B Acosta-Maldonado, D Vilar-Compte, P Cornejo-Juárez
BACKGROUND: Hematopoietic stem cell transplantation (HSCT) has been used as treatment in different hematologic and solid malignancies. The aim of this study was to describe the frequency of infectious complications, microbiology, and outcome in patients undergoing HSCT in Mexico during the pre-engraftment period and the impact on mortality rates at 12 months. METHODS: We conducted a retrospective study of all hematologic malignancies that received HSCT from January 2009 and December 2014, at an oncology reference center...
July 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28735318/trends-of-bloodstream-infections-in-a-university-greek-hospital-during-a-three-year-period-incidence-of-multidrug-resistant-bacteria-and-seasonality-in-gram-negative-predominance
#16
Fevronia Kolonitsiou, Matthaios Papadimitriou-Olivgeris, Anastasia Spiliopoulou, Vasiliki Stamouli, Vasileios Papakostas, Eleni Apostolopoulou, Christos Panagiotopoulos, Markos Marangos, Evangelos D Anastassiou, Myrto Christofidou, Iris Spiliopoulou
The aim of the study was to assess the epidemiology, the incidence of multidrug-resistant bacteria and bloodstream infections' (BSIs) seasonality in a university hospital. This retrospective study was carried out in the University General Hospital of Patras, Greece, during 2011-13 y. Blood cultures from patients with clinical presentation suggestive of bloodstream infection were performed by the BacT/ALERT System. Isolates were identified by Vitek 2 Advanced Expert System. Antibiotic susceptibility testing was performed by the disk diffusion method and E-test...
July 6, 2017: Polish Journal of Microbiology
https://www.readbyqxmd.com/read/28735050/antimicrobial-resistance-profiles-and-genotypes-of-extended-spectrum-%C3%AE-lactamase-and-ampc-%C3%AE-lactamase-producing-klebsiella-pneumoniae-isolated-from-dogs-in-beijing-china
#17
Yanhan Liu, Yonghui Yang, Yanyun Chen, Zhaofei Xia
OBJECTIVES: Klebsiella pneumoniae, which exists in the intestinal and respiratory tracts of humans and animals, is an important conditional pathogen in many animals. The aim of the current study was to investigate the antimicrobial resistance profiles and genotypes of extended-spectrum β-lactamase (ESBL) - and AmpC β-lactamase-producing K. pneumoniae isolated from dogs. METHODS: A total of 285 isolates, collected from fecal and urine samples of diseased dogs in a Veterinary Teaching Hospital in Beijing, were characterized by antimicrobial susceptibility testing and screened for ESBL and AmpC β-lactamase phenotypes...
July 19, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28734432/outbreak-of-middle-east-respiratory-syndrome-coronavirus-causes-high-fatality-after-cardiac-operations
#18
Rakan I Nazer
Middle East respiratory syndrome-coronavirus (MERS-CoV) resembles a severe form of community-acquired pneumonia initially reported in Saudi Arabia in 2012. The MERS-CoV epidemic poses a big challenge because of its high mortality. In January 2015, a patient who was potentially incubating MERS-CoV arrived from the emergency department of another hospital and was admitted with acute coronary syndrome. This resulted in an outbreak in the cardiac surgery ward that caused the deaths of 5 of 6 patients who had undergone cardiac operations...
August 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28732822/atypical-coverage-in-community-acquired-pneumonia-after-outpatient-beta-lactam-monotherapy
#19
Cornelis H van Werkhoven, Ewoudt M W van de Garde, Jan Jelrik Oosterheert, Douwe F Postma, Marc J M Bonten
INTRODUCTION: In adults hospitalized with community-acquired pneumonia (CAP) after >48 h of outpatient beta-lactam monotherapy, coverage of atypical pathogens is recommended based on expert opinion. METHODS: In a post-hoc analysis of a large study of CAP treatment we included patients who received beta-lactam monotherapy for >48 h before hospitalization. Length of hospital stay (LOS), 30-day mortality, and number of treatment escalations were compared for those that continued beta-lactam monotherapy and those that received atypical coverage at admission...
August 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28732788/occurrence-and-clonal-diversity-of-multidrug-resistant-klebsiella-pneumoniae-recovered-from-inanimate-surfaces-in-algerian-hospital-environment-first-report-of-arma-qnrb-and-aac-6-ib-cr-genes
#20
Karima Zenati, Farida Sahli, Vincent Garcia, Sofiane Bakour, Djellali Belhadi, Jean Marc Rolain, Abdelaziz Touati
PURPOSE: The aim of this study is to characterize the molecular support of antibiotic resistance in MDR K. pneumonaie recovered from inanimate surfaces between March 2012 to February 2014 in three teaching hospitals (Setif, Bejaia and Constantine) in Algeria. RESULTS: Forty four K. pneumoniae producing ESBL were detected and blaCTX-M-15 and blaCTX-M-3 were detected respectively in 41 and 3 isolates. These K. pneumoniae isolates producing ESBL were also resistant to gentamicin (87%), tobramicin (87%), ciprofloxacin (66%) and ofloxacin (62%)...
July 18, 2017: Journal of Global Antimicrobial Resistance
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