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https://www.readbyqxmd.com/read/28813640/innate-immune-signaling-in-the-ventral-tegmental-area-contributes-to-drug-primed-reinstatement-of-cocaine-seeking
#1
Kyle T Brown, Sophia C Levis, Casey E O'Neill, Alexis L Northcutt, Timothy J Fabisiak, Linda R Watkins, Ryan K Bachtell
Cocaine addiction is a chronic relapsing disorder characterized by persistent perturbations to an organism's homeostatic processes that result in maladaptive drug seeking. Although considerable attention has been directed at the consequences of neuronal changes following chronic cocaine taking, few studies have examined the role of microglia, the brain's resident immune cells, following chronic cocaine administration. Toll-Like Receptor 4 (TLR4) is a molecular pattern receptor that recognizes pathogens, danger signals, and xenobiotics and induces proinflammatory signaling in the central nervous system...
August 13, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28812815/stakeholders-perspectives-on-the-success-drivers-in-ghana-s-national-health-insurance-scheme-identifying-policy-translation-issues
#2
Adam Fusheini, Gordon Marnoch, Ann Marie Gray
BACKGROUND: Ghana's National Health Insurance Scheme (NHIS), established by an Act of Parliament (Act 650), in 2003 and since replaced by Act 852 of 2012 remains, in African terms, unprecedented in terms of growth and coverage. As a result, the scheme has received praise for its associated legal reforms, clinical audit mechanisms and for serving as a hub for knowledge sharing and learning within the context of South-South cooperation. The scheme continues to shape national health insurance thinking in Africa...
October 1, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812792/a-case-for-open-network-health-systems-systems-as-networks-in-public-mental-health
#3
Michael Grant Rhodes, Marten W de Vries
Increases in incidents involving so-called confused persons have brought attention to the potential costs of recent changes to public mental health (PMH) services in the Netherlands. Decentralized under the (Community) Participation Act (2014), local governments must find resources to compensate for reduced central funding to such services or "innovate." But innovation, even when pressure for change is intense, is difficult. This perspective paper describes experience during and after an investigation into a particularly violent incident and murder...
January 8, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28811906/induced-vomiting-for-attention-seeking-and-secondary-gain-an-unusual-cause-of-pseudo-resistant-hypertension
#4
Katerina Zakka, Mohamad Bitar, Bassel Lakkis, Sahar H Koubar
In patients with complex psychosocial history presenting with resistant hypertension, observed therapy should be implemented early on to avoid unnecessary investigations and delayed diagnosis.
August 2017: JRSM Open
https://www.readbyqxmd.com/read/28810667/understanding-data-sources-to-measure-patient-retention-in-hiv-care-in-sub-saharan-africa
#5
Kate Clouse, Tamsin Phillips, Landon Myer
Antiretroviral therapy (ART) programs in sub-Saharan Africa are moving towards universal treatment, yet the success of these programs is threatened by gaps within the continuum of HIV care. In this commentary, we seek to draw attention to the advantages and limitations of different data sources currently used for measuring retention in HIV care. Within the context of a piecemeal combination of imperfect data sources, selecting a gold standard of collecting retention data is difficult. Currently, our data systems for measuring retention provide an incomplete picture of the health of our national ART systems and, thus, the health of our patients...
July 1, 2017: International Health
https://www.readbyqxmd.com/read/28801052/accompaniment-of-second-trimester-abortions-the-model-of-the-feminist-socorrista-network-of-argentina
#6
Ruth Zurbriggen, Brianna Keefe-Oates, Caitlin Gerdts
OBJECTIVE: Legal restrictions on abortion access impact the safety and timing of abortion. Women affected by these laws face barriers to safe care that often result in abortion being delayed. Second-trimester abortion affects vulnerable groups of women disproportionately, and is often more difficult to access. In Argentina, where abortion is legally restricted except in cases of rape or threat to the health of the woman, the Socorristas en Red, a feminist network, offers a model of accompaniment wherein they provide information and support to women seeking second-trimester abortions...
August 8, 2017: Contraception
https://www.readbyqxmd.com/read/28800529/mental-health-stigma-and-barriers-to-mental-health-care-for-first-responders-a-systematic-review-and-meta-analysis
#7
REVIEW
Peter T Haugen, Aileen M McCrillis, Geert E Smid, Mirjam J Nijdam
OBJECTIVE: It is unclear how many first responders experience barriers to care and stigma regarding mental health care, and how this influences their help-seeking. A systematic review and meta-analysis was conducted on barriers to care and mental health stigma in first responders and their empirical relationship with psychosocial and psychiatric variables. METHODS: The databases Medline, Embase PsycINFO, CINAHL, PILOTS, LILACS, Sociological Abstracts, SocINDEX, and Social Citation Index were searched to identify relevant studies...
August 5, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28800502/spotlight-on-equality-of-employment-opportunities-a-qualitative-study-of-job-seeking-experiences-of-graduating-nurses-and-physiotherapists-from-black-and-minority-ethnic-backgrounds
#8
John Hammond, Sylvie Marshall-Lucette, Nigel Davies, Fiona Ross, Ruth Harris
BACKGROUND: There is growing attention in the UK and internationally to the representation of black and minority ethnic groups in healthcare education and the workplace. Although the NHS workforce is very diverse, ethnic minorities are unevenly spread across occupations, and considerably underrepresented in senior positions. Previous research has highlighted that this inequality also exists at junior levels with newly qualified nurses from non-White/British ethnic groups being less likely to get a job at graduation than their White/British colleagues...
August 1, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28794237/prolonged-immigration-detention-complicity-and-boycotts
#9
Melanie Jansen, Alanna Sue Tin, David Isaacs
Australia's punitive policy towards people seeking asylum deliberately causes severe psychological harm and meets recognised definitions of torture. Consequently, there is a tension between doctors' obligation not to be complicit in torture and doctors' obligation to provide best possible care to their patients, including those seeking asylum. In this paper, we explore the nature of complicity and discuss the arguments for and against a proposed call for doctors to boycott working in immigration detention. We conclude that a degree of complicity is unavoidable when working in immigration detention, but that it may be ethically justifiable...
August 9, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28783009/substituting-freshwater-can-ocean-desalination-and-water-recycling-capacities-substitute-for-groundwater-depletion-in-california
#10
Pierre Badiuzzaman, Eoin McLaughlin, Darren McCauley
While the sustainability of resource depletion is a longstanding environmental concern, wider attention has recently been given to growing water scarcity and groundwater depletion. This study seeks to test the substitutability assumption embedded in weak sustainability indicators using a case study of Californian water supply. The volume of groundwater depletion is used as a proxy for unsustainable water consumption, and defined by synthesising existing research estimates into low, medium and high depletion baselines...
August 3, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28782094/comparative-sem-analysis-of-nine-f22-aligner-cleaning-strategies
#11
Luca Lombardo, Marco Martini, Francesca Cervinara, Giorgio Alfredo Spedicato, Teresa Oliverio, Giuseppe Siciliani
BACKGROUND: The orthodontics industry has paid great attention to the aesthetics of orthodontic appliances, seeking to make them as invisible as possible. There are several advantages to clear aligner systems, including aesthetics, comfort, chairside time reduction, and the fact that they can be removed for meals and oral hygiene procedures. METHODS: Five patients were each given a series of F22 aligners, each to be worn for 14 days and nights, with the exception of meal and brushing times...
December 2017: Progress in Orthodontics
https://www.readbyqxmd.com/read/28774053/feasibility-of-using-unbound-mixed-recycled-aggregates-from-cdw-over-expansive-clay-subgrade-in-unpaved-rural-roads
#12
Isaac Del Rey, Jesús Ayuso, Adela P Galvín, José R Jiménez, Auxi Barbudo
Social awareness aims to increase practical skills, such as sustainable development, which seeks to increase the use of different types of waste in construction activities. Although insufficient attention is sometimes given to these actions, it is essential to spread information regarding new studies in the field of waste recycling, which encourages and promotes waste use. Reusing and recycling construction waste in the creation of buildings and infrastructure are fundamental strategies to achieving sustainability in the construction and engineering sectors...
November 17, 2016: Materials
https://www.readbyqxmd.com/read/28771876/i-was-yelled-at-intimidated-and-treated-unfairly-nursing-students-experiences-of-being-bullied-in-clinical-and-academic-settings
#13
Helen Courtney-Pratt, Jacqueline Pich, Tracy Levett-Jones, Annette Moxey
AIM: To present findings from a study that explored nursing students' experiences of bullying in clinical and academic settings, the strategies used to negotiate bullying, and recommendations for empowering future students. BACKGROUND: Nursing students are identified as a group who are at particular risk of bullying. Numerous studies have examined students' experiences of bullying in clinical contexts by qualified nurses, however, there has been far less attention to the bullying that occurs in academic settings where the perpetrators are university staff and other students...
August 3, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28770662/complications-in-extracorporeal-shockwave-lithotripsy-a-cohort-study
#14
Magnus Wagenius, Jon Jakobsson, Johan Stranne, Adam Linder
OBJECTIVE: The aim of this study was to evaluate clinically relevant complications within 14 days after extracorporeal shockwave lithotripsy (ESWL) in a modern setting. MATERIALS AND METHODS: Consecutive ESWL treatments between 2009 and 2015 in Ängelholm Hospital, Sweden, were analyzed retrospectively. The primary outcome was complications in patients seeking medical attention within 14 days after ESWL. Multivariable analysis was used to adjust for confounders such as diabetes, stone size and location, and presence of a urinary stent...
August 3, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28768506/a-qualitative-exploration-of-cervical-and-breast-cancer-stigma-in-karnataka-india
#15
Laura Nyblade, Melissa Stockton, Sandra Travasso, Suneeta Krishnan
BACKGROUND: Breast and cervical cancer are two of the most common cancers among women worldwide and were the two leading causes of cancer related death for women in India in 2013. While it is recognized that psychosocial and cultural factors influence access to education, prevention, screening and treatment, the role of stigma related to these two cancers has received limited attention. METHODS: Two qualitative exploratory studies. One focusing on cervical cancer, the other on breast cancer, were conducted in Karnataka, India using in-depth interviews and focus group discussions...
August 2, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28766027/telephone-delivered-mindfulness-training-for-people-living-with-hiv-a-qualitative-360%C3%A2-inquiry
#16
Rochelle K Rosen, Larissa A McGarrity, Elena Salmoirago-Blotcher, Carla Rich, Aadia Rana, Michael P Carey
For people living with HIV and AIDS (PLWHA), life stress often undermines quality of life and interferes with medical care. Mindfulness training (MT) may help PLWHA to manage stress. Because standard MT protocols can be burdensome, we explored telephone delivery as a potentially more feasible approach. We used an innovative 360° qualitative inquiry to seek input regarding telephone-delivery of MT for PLWHA in advance of a planned intervention trial. We also sought input on a time- and attention-matched control...
August 1, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28762584/drug-related-stigma-and-access-to-care-among-people-who-inject-drugs-in-vietnam
#17
Chiao-Wen Lan, Chunqing Lin, Duong Cong Thanh, Li Li
INTRODUCTION AND AIMS: There are considerable challenges faced by people with a history of injecting drug use (PWID) in Vietnam, including drug-related stigma and lack of access to healthcare. Seeking and utilising healthcare, as well as harm reduction programs for PWID, are often hampered by drug-related stigma. This study aimed to examine the impacts of drug-related stigma on access to care and utilisation of harm reduction programs among PWID in Vietnam. DESIGN AND METHODS: A cross-sectional study was conducted in two provinces in Vietnam, Phú Thọ and Vinh Phúc...
August 1, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28762471/clinical-presentation-of-terbinafine-induced-severe-liver-injury-and-the-value-of-laboratory-monitoring-a-critically-appraised-topic
#18
REVIEW
O N Kramer, J Albrecht
CONTEXT: Many physicians monitor liver function tests during terbinafine therapy. OBJECTIVE: Evaluate the symptoms of published cases of terbinafine associated severe DILI (Drug Induced Liver Injury) to assess the utility of laboratory monitoring. DATA SOURCES: We based our search on the Liver Tox database of the National Institute of Health, but searched PUBMED as well as EMBASE. In addition, we hand-searched the references of the papers we found...
August 1, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28759721/microchip-circulation-drastically-accelerates-amyloid-aggregation-of-1-42-%C3%AE-amyloid-peptide-from-felis-catus
#19
Witold Gospodarczyk, Maciej Kozak
Amyloid aggregation process of amyloid beta 1-42 peptide is responsible for Alzheimer disease, concerning millions of elderly people worldwide. Although there has a great deal of attention made to tackle this disease, there still has not been found any medicine for this fatal disorder. In order to come against this challenge, it is vital to thoroughly understand the molecular mechanism underlying peptide amyloid aggregation process, as well as seek for substances which could hamper this aggregation. In order to shed light on mechanisms leading to amyloidogenesis, we employed a microfluidic system to determine the possible influence of in vivo-like flow in microchip channel itself on peptide amyloidogenesis...
July 31, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/28759575/barriers-to-sexual-and-reproductive-healthcare-services-as-experienced-by-female-sex-workers-and-service-providers-in-dhaka-city-bangladesh
#20
Tasnuva Wahed, Anadil Alam, Salima Sultana, Monjur Rahman, Nazmul Alam, Monika Martens, Ratana Somrongthong
OBJECTIVES: This study aimed to identify the barriers female sex workers (FSWs) in Bangladesh face with regard to accessing sexual and reproductive health (SRH) care, and assess the satisfaction with the healthcare received. METHODS: Data were collected from coverage areas of four community-based drop-in-centers (DICs) in Dhaka where sexually transmitted infection (STI) and human immunovirus (HIV) prevention interventions have been implemented for FSWs. A total of 731 FSWs aged 15-49 years were surveyed...
2017: PloS One
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