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Mechanical back pain

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https://www.readbyqxmd.com/read/28546875/spinal-cord-infarct-caused-from-suspected-fibrocartilaginous-embolism
#1
Ayham M Alkhachroum, Danielle Weiss, Alan Lerner, Michael A De Georgia
INTRODUCTION: We report a case of spinal cord infarct as a result of suspected fibrocartilaginous embolism (FCE). CASE PRESENTATION: A 23-year-old man presented with sudden onset cervical and upper back pain followed by progressive weakness in his extremities after throwing a baseball. History, neurologic examination and spinal cord imaging were consistent with spinal cord infarct. We believe the cause was from FCE. DISCUSSION: Though rare, physicians should be familiar with this diagnosis and the proposed mechanisms...
2017: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/28546874/acute-paraparesis-and-sensory-loss-following-intravenous-corticosteroid-administration-in-a-case-of-longitudinally-extensive-transverse-myelitis-caused-by-spinal-dural-arteriovenous-fistula-case-report-and-review-of-literature
#2
Michael A DiSano, Russell Cerejo, MaryAnn Mays
INTRODUCTION: The underlying causes of longitudinally extensive transverse myelitis (LETM) are broad and include inflammatory processes, compression and spinal dural arteriovenous fistula (SDAVF). Presenting symptoms of SDAVF are nonspecific and often go misdiagnosed. Acute clinical deterioration from SDAVF has been described following exertion or valsalva. However, deterioration has been recently recognized following steroid administration and may contribute to increased morbidity. CASE PRESENTATION: We describe a 63-year-old woman with a 2-year history of intermittent lower extremity numbness and back pain, lumbar stenosis, who presented with subacute worsening of symptoms following a course of oral steroids for an upper respiratory infection...
2017: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/28545508/open-label-versus-double-blind-placebo-treatment-in-irritable-bowel-syndrome-study-protocol-for-a-randomized-controlled-trial
#3
Sarah Ballou, Ted J Kaptchuk, William Hirsch, Judy Nee, Johanna Iturrino, Kathryn T Hall, John M Kelley, Vivian Cheng, Irving Kirsch, Eric Jacobson, Lisa Conboy, Anthony Lembo, Roger B Davis
BACKGROUND: Placebo medications, by definition, are composed of inactive ingredients that have no physiological effect on symptoms. Nonetheless, administration of placebo in randomized controlled trials (RCTs) and in clinical settings has been demonstrated to have significant impact on many physical and psychological complaints. Until recently, conventional wisdom has suggested that patients must believe that placebo pills actually contain (or, at least, might possibly contain) active medication in order to elicit a response to placebo...
May 25, 2017: Trials
https://www.readbyqxmd.com/read/28538598/the-need-for-multidimensional-stratification-of-chronic-low-back-pain-lbp
#4
Yoga Raja Rampersaud, Andrew Bidos, Caroline Fanti, Anthony V Perruccio
STUDY DESIGN: Cross-sectional study of Canadian LBP patients seeking primary care. OBJECTIVE: Determine which existing primary care LBP stratification schema is associated with distinct sub-populations as characterized by easily identifiable primary epidemiological factors. SUMMARY OF BACKGROUND DATA: Low back pain (LBP) is among the most frequent reasons for visits to primary care physicians and a leading cause of years lived with disability...
May 22, 2017: Spine
https://www.readbyqxmd.com/read/28535553/differences-in-pain-processing-between-patients-with-chronic-low-back-pain-recurrent-low-back-pain-and-fibromyalgia
#5
Dorien Goubert, Lieven Danneels, Thomas Graven-Nielsen, Filip Descheemaeker, Mira Meeus
BACKGROUND: The impairment in musculoskeletal structures in patients with low back pain (LBP) is often disproportionate to their complaint. Therefore, the need arises for exploration of alternative mechanisms contributing to the origin and maintenance of non-specific LBP. The recent focus has been on central nervous system phenomena in LBP and the pathophysiological mechanisms underlying the various symptoms and characteristics of chronic pain. Knowledge concerning changes in pain processing in LBP remains ambiguous, partly due to the diversity in the LBP population...
May 2017: Pain Physician
https://www.readbyqxmd.com/read/28523481/mild-depression-in-low-back-pain-the-interaction-of-thought-suppression-and-stress-plays-a-role-especially-in-female-patients
#6
Konietzny Kerstin, Chehadi Omar, Streitlein-Böhme Irmgard, Rusche Herbert, Willburger Roland, Hasenbring Monika Ilona
PURPOSE: Mild depression has been shown as a precursor and as a consequence of low back pain, even in early phases of acute or subacute pain. Chronic daily life stress as well as dysfunctional pain-related cognitions such as thought suppression (TS) seem to play a role in the pain-depression cycle; however, the mechanisms of these associations are less understood. Experimentally induced TS, conceived as the attempt to directly suppress sensations such as pain, has been shown to paradoxically cause a delayed and non-volitional return of the suppressed thoughts and sensations and to increase affective distress...
May 18, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28522289/epidemiology-of-pain-and-relation-to-psychiatric-disorders
#7
REVIEW
Ana Miriam Velly, Shrisha Mohit
Chronic pain is a common pain condition. Some psychiatric disorders, such as anxiety and depression, are also common in the general population. Epidemiological studies found that some psychiatric disorders are more commonly found among persons with chronic pain (e.g., headache, back pain) than those without chronic pain. Why those psychiatric disorders co-occur with chronic pain, however, is not well understood. Further, studies demonstrated that some psychiatric disorders, such as depression, increase the risk of chronic pain as well as its persistence...
May 15, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28508761/posterior-branches-of-lumbar-spinal-nerves-part-ii-lumbar-facet-syndrome-pathomechanism-symptomatology-and-diagnostic-work-up
#8
Katarzyna Kozera, Bogdan Ciszek, Paweł Szaro
Posterior branches of the lumbar spinal nerves are the anatomic substrate of pain in the lower back, sacrum and the gluteal area. Such pain may be associated with various pathologies which cause pain in the posterior branches of the lumbar spinal nerves due to entrapment, mechanical irritation or inflammatory reaction and/or degeneration. The posterior branches are of significant functional importance, which is related to the function of the structures they supply, including facet joints, which are the basic biomechanical units of the spine...
April 12, 2017: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28506227/associations-between-disc-space-narrowing-anterior-osteophytes-and-disability-in-chronic-mechanical-low-back-pain-a-cross-sectional-study
#9
Romain Shanil Perera, Poruwalage Harsha Dissanayake, Upul Senarath, Lalith Sirimevan Wijayaratne, Aranjan Lional Karunanayake, Vajira Harshadeva Weerabaddana Dissanayake
BACKGROUND: Radiographic features of lumbar disc degeneration (LDD) are common findings in patients with chronic mechanical low back pain; however, its role in disability and intensity of pain is debatable. This study aims to investigate the associations of the x-ray features of LDD and lumbar spondylolisthesis with severity of disability and intensity of pain. METHODS: A cross-sectional study was conducted on 439 patients with chronic mechanical low back pain who attended the rheumatology clinic, National Hospital of Sri Lanka, Colombo, from May 2012 to May 2014...
May 15, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28505228/associations-of-musculoskeletal-pain-with-mobility-in-older-adults-potential-cerebral-mechanisms
#10
Yenisel Cruz-Almeida, Andrea Rosso, Zachary Marcum, Tamara Harris, Anne B Newman, Michael Nevitt, Suzanne Satterfield, Kristine Yaffe, Caterina Rosano
Background: Musculoskeletal pain is highly prevalent and limits mobility in older adults. A potential mechanism by which pain affects mobility could be through its negative impact on the brain. We examined whether structural integrity of cerebral gray and white matter (WM) mediated the relationship between pain and mobility in community-dwelling older adults. Methods: Musculoskeletal pain, gait speed, and neuroimaging data were obtained concurrently from the Health ABC study (mean age = 83/56% female, n = 212)...
May 13, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28503875/a-rare-vascular-complication-in-a-patient-with-essential-thrombocythaemia-spontaneous-abdominal-aortic-dissection
#11
Ye Chen, Xue Han, Fang Wang, Beibei Bai, Yingchun Wang
A 27-year-old woman complained of waist and back pain. Abdominal computed tomography angiography showed abdominal aortic dissection, the blood count revealed a high platelet count of 1655 × 10(9) /L. Negative for JAK2V617F, CALR and MPL mutations (i.e. triple-negative), the patient was diagnosed as essential thrombocythaemia (ET) with abdominal aortic dissection and was treated with cytoreduction and antiplatelet drugs. Cases of abdominal aortic dissection in ET have not been previously reported. As such, we proposed a mechanism of abdominal aortic dissection caused by endothelial dysfunction and further emphasised appropriate management in ET with abdominal aortic dissection...
May 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28503674/identifying-brain-nociceptive-information-transmission-in-patients-with-chronic-somatic-pain
#12
Don A Davis, Mariam E Ghantous, Melissa A Farmer, Alexis T Baria, A Vania Apkarian
INTRODUCTION: Recent advances regarding mechanisms of chronic pain emphasize the role of corticolimbic circuitry in predicting risk for chronic pain, independently from site of injury-related parameters. These results compel revisiting the role of peripheral nociceptive signaling in chronic pain. We address this issue by examining what brain circuitry transmit information regarding the intensity of chronic pain and how this information may be related to a common co-morbidity, depression...
October 2016: Pain Reports (Baltimore, Md.)
https://www.readbyqxmd.com/read/28501720/characterization-and-restoration-of-degenerated-ivd-function-with-an-injectable-in-situ-gelling-alginate-hydrogel-an-in-vitro-and-ex-vivo-study
#13
Emily A Growney Kalaf, Meghana Pendyala, J Gary Bledsoe, Scott A Sell
Intervertebral disc (IVD) degeneration is a naturally, irreparable process that causes loss in IVD hydration, cellularity, and, mechanical stability. Invasive surgical attempts to ease back pain and, radiculopathy have shown to cause increased degeneration along the rest, of the spine. Due to its highly tunable mechanical and degradation, properties, alginate is a viable option for a less-invasive injectable, repair for IVD degeneration. This study centers on the characterization, of in situ gelling alginate and subsequent injection into enzymatically, degraded motion segments...
May 7, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28495521/efficacy-of-local-glucocorticoid-after-local-anesthetic-in-bertolotti-s-syndrome-a-randomized-placebo-controlled-double-blind-trial
#14
Joëlle Glémarec, Stéphane Varin, Céline Cozic, Gilles Tanguy, Christelle Volteau, Philippe Montigny, Benoît Le Goff, Christelle Darrieutort Laffite C, Yves Maugars, Grégoire Cormier
OBJECTIVE: The primary objective of this study was to compare the efficacy of local injection of a local anesthetic with a glucocorticoid versus a local anesthetic with saline to treat low back pain due to lumbosacral transitional vertebras (LSTV) with a pseudoarticulation. METHODS: A randomized placebo-controlled double-blind study was conducted in patients with unilateral low back pain ascribed clinically to LSTV. Patients were randomized to lidocaine plus saline (LS group) or lidocaine plus cortivazol (LC group) injected locally under computed tomography guidance...
May 8, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28491208/joint-pain-epidemiology-and-analgesic-usage-in-madagascar
#15
Luc Hervé Samison, Fidiniaina Mamy Randriatsarafara, Stéphane Ralandison
INTRODUCTION: To describe the epidemiology of joint pains and document analgesics usage in an African context. METHODS: Patients suffering from joint pain were recruited from nine sites located in Antananarivo, Madagascar, including 6 hospital services and 3 clinics. Doctors collected information on the etiology and characteristics of the patients' pain. Analgesics prescribed by these doctors were also documented. RESULTS: In total, 400 patients were enrolled in the study (52...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28486045/in-vitro-generated-intervertebral-discs-towards-engineering-tissue-integration
#16
Jonathan Iu, Eric Massicotte, Shu-Qiu Li, Mark B Hurtig, Ehsan Toyserkani, J Paul Santerre, Rita Kandel
The intervertebral disc (IVD) is composed of nucleus pulposus (NP) surrounded by multilamellated annulus fibrosus (AF), and is located between the vertebral bodies. Current treatments for chronic neck or low back pain do not completely restore the functionality of degenerated IVDs. Thus developing biological disc replacements is an approach of great interest. Given the complex structure of the IVD, tissue engineering of the individual IVD components and then combining them together may be the only way to achieve this...
May 9, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28481838/contribution-of-endocannabinoid-gene-expression-and-genotype-on-low-back-pain-susceptibility-and-chronicity
#17
Divya Ramesh, Amy D'Agata, Angela Starkweather, Erin Young
A major research emphasis has been focused on defining the molecular changes that occur from acute to chronic pain in order to identify potential therapeutic targets for chronic pain. As the endocannabinoid system is dynamically involved in pain signaling, a plausible mechanism that may contribute to chronic pain vulnerability involves alterations in the amount of circulating endocannabinoids. Therefore, this study sought to examine cannabinoid type-1 (CNR1), type-2 (CNR2) receptors, fatty acid amide hydrolase (FAAH) and the vanilloid receptor (TRPV1) gene expression profiles among individuals with acute and chronic LBP at their baseline visit...
May 5, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28480437/bibliometric-analysis-of-acupuncture-research-fronts-and-their-worldwide-distribution-over-three-decades
#18
Jun-Ying Fu, Xu Zhang, Yun-Hua Zhao, He-Feng Tong, Dar-Zen Chen, Mu-Hsuan Huang
BACKGROUND: Considerable research has been conducted on acupuncture worldwide. This study chronologically examined the changing features and research fronts of acupuncture and elucidated the differences among the six most productive countries. METHODS: Bibliographic coupling is a powerful tool for identifying the research fronts of a field. Acupuncture-related publications worldwide and from the six most productive countries during 1983-2012 were retrieved from the Science Citation Index Expanded and Social Science Citation Index...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28474495/children-with-chronic-stress-induced-recurrent-muscle-pain-have-enhanced-startle-reaction
#19
G Alfvén, S Grillner, E Andersson
BACKGROUND: Children with recurrent pain of negative chronic stress origin from different locations have a characteristic pattern of tender points in the temporal, trapezoid, great pectoral and abdominal muscles. We tested the hypothesis that the startle reaction is activated in these children and that some of the startle-activated muscles are related to the tender point pattern and the recurrent pain. METHODS: In children/adolescents, aged 10-17 years, 19 with recurrent psychosomatic pain (PAIN) and 23 controls (CON) we measured and analysed resting activity and acoustic startle response with electromyography (EMG) for the muscles involved in the pattern of tender points and also the lumbar erector spinae...
May 4, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28468504/dynamic-mechanical-response-of-polyvinyl-alcohol-gelatin-theta-gels-for-nucleus-pulposus-tissue-replacement
#20
Patrick N Charron, Sarah E Blatt, Canaan McKenzie, Rachael A Oldinski
Intervertebral disk degeneration is one of the most significant contributors to low back pain. Thus, there is significant interest in designing new treatments and nucleus pulposus (NP) tissue replacements. Herein, the authors propose a biosynthetic material, comprised of a polyvinyl alcohol (PVA) and gelatin theta-gel, as an acellular NP tissue replacement. Theta-gels form during the solidification of PVA and gelatin (phase I), and the phase separation of a disklike short-chain polyethylene glycol (PEG, phase II)...
May 3, 2017: Biointerphases
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