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https://www.readbyqxmd.com/read/29122281/good-functional-outcome-in-patients-suffering-fragility-fractures-of-the-pelvis-treated-with-percutaneous-screw-stabilisation-assessment-of-complications-and-factors-influencing-failure
#1
Henrik Eckardt, Alexander Egger, Rebecca Maria Hasler, Christoph J Zech, Werner Vach, Norbert Suhm, Mario Morgenstern, Franziska Saxer
BACKGROUND: Low energy pelvic ring fractures in the elderly have traditionally been treated conservatively, a treatment with potential long-term complications and loss of self-independence. Percutaneous screw stabilisation of the posterior pelvic ring is a new treatment modality that enables immediate mobilisation. The aim of this study was to assess the functional outcome after sacroiliac stabilisation in the elderly. METHODS: All elderly patients with a surgically stabilised low energy pelvic fracture between 2010 and 2015 were included...
November 4, 2017: Injury
https://www.readbyqxmd.com/read/29048688/is-endoprosthetic-replacement-of-the-proximal-femur-appropriate-in-the-comorbid-patient
#2
Arun Khajuria, Jonathon Ward, George Cooper, Jonathon Stevenson, Michael Parry, Lee Jeys
INTRODUCTION: Patients with failed hip arthroplasty requiring extensive femoral reconstruction often present with a multitude of comorbidities. Many treatment options limit initial mobilisation relying on bone graft incorporation. The use of endoprosthetic replacement (EPR), despite often being a "last resort", offers an expeditious solution with early mobilisation that is crucial in the comorbid individual. Many perceive that the surgical insult of EPR is associated with an increased mortality...
October 16, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29042844/designing-a-care-pathway-model-a-case-study-of-the-outpatient-total-hip-arthroplasty-care-pathway
#3
Robin I Oosterholt, Lianne Wl Simonse, Stella U Boess, Stephan Bw Vehmeijer
INTRODUCTION: Although the clinical attributes of total hip arthroplasty (THA) care pathways have been thoroughly researched, a detailed understanding of the equally important organisational attributes is still lacking. The aim of this article is to contribute with a model of the outpatient THA care pathway that depicts how the care team should be organised to enable patient discharge on the day of surgery. THEORY: The outpatient THA care pathway enables patients to be discharged on the day of surgery, shortening the length of stay and intensifying the provision and organisation of care...
March 9, 2017: International Journal of Integrated Care
https://www.readbyqxmd.com/read/29042001/recovery-from-vegetative-state-of-patients-with-a-severe-brain-injury-a-4-year-real-practice-prospective-cohort-study
#4
Alessio Baricich, A de Sire, E Antoniono, F Gozzerino, G Lamberti, C Cisari, M Invernizzi
Patients who have suffered severe traumatic or nontraumatic brain injuries can show a progressive recovery, transitioning through a range of clinical conditions. They may progress from coma to a vegetative state (VS) and/or a minimally conscious state (MCS). A longer duration of the VS is known to be related to a lower probability of emergence from it; furthermore, the literature seems to lack evidence of late improvements in these patients. This real-practice prospective cohort study was conducted in inpatients in a VS following a severe brain injury, consecutively admitted to a vegetative state unit (VSU)...
July 2017: Functional Neurology
https://www.readbyqxmd.com/read/29037626/the-acute-effects-of-ankle-mobilisations-on-lower-extremity-joint-kinematics
#5
Louis P Howe
INTRODUCTION: Previous investigations have identified compensatory movement strategies (CMS) within the lower extremity or lumbopelvic complex during closed chain exercises may be associated with a loss of ankle dorsiflexion range of motion (ROM). The aim of this study was to investigate the acute effects of ankle mobilisations on proximal joint kinematics during a movement task that demands a high amount of ankle dorsiflexion ROM. METHODS: Eight healthy males (mean (SD) age 25 (4) years) demonstrating side-to-side asymmetry during the weight-bearing lunge test (WBLT) and CMS during the single-leg step-down exercise were accepted for this study...
October 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/28893014/comparison-of-continuous-femoral-nerve-block-versus-local-infiltration-analgesia-as-a-postoperative-analgesia-in-unilateral-total-knee-arthroplasty
#6
Deepika Chaubey, Hari Krishan Mahajan, Parshu Ram Chauhan, Preeti S Govind, Pushpinder Singh, Ravinder Dhanevar, Abhinav Gupta
INTRODUCTION: Local infiltration of knee joint in arthroplasty, provide postoperative analgesia and preserves motor power of quadriceps, which helps in early mobilisation, as compared to femoral nerve block which paralyses vastus medialis. AIM: To compare the quality of postoperative analgesia provided by femoral nerve block and local infiltration in unilateral Total Knee Arthroplasty (TKA). MATERIALS AND METHODS: A prospective study was conducted on 60 patients (25-65 years) of ASA I and II, which were randomly(using random number table) divided into two groups - Group 1-femoral nerve block (FNB) and Group 2-Local Infiltration Analgesia (LIA)...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28882509/clinical-benefits-of-joint-mobilization-on-ankle-sprains-a-systematic-review-and-meta-analysis
#7
REVIEW
Ishanka Weerasekara, Peter Osmotherly, Suzanne Snodgrass, Jodie Marquez, Rutger de Zoete, Darren A Rivett
OBJECTIVE: To assess the clinical benefits of joint mobilization for ankle sprains. DATA SOURCES: MEDLINE, MEDLINE In-Process, Embase, AMED, PsycINFO, CINAHL, Cochrane Library, PEDro, Scopus, SPORTDiscus, and Dissertations and Theses were searched from inception to June 2017. STUDY SELECTION: Studies investigating humans with grade I or II lateral or medial sprains of the ankle in any pathologic state from acute to chronic, who had been treated with joint mobilization were considered for inclusion...
September 4, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28879640/creative-tensions-mutual-responsiveness-adapted-to-private-sector-research-and-development
#8
Matti Sonck, Lotte Asveld, Laurens Landeweerd, Patricia Osseweijer
The concept of mutual responsiveness is currently based on little empirical data in the literature of Responsible Research and Innovation (RRI). This paper explores RRI's idea of mutual responsiveness in the light of recent RRI case studies on private sector research and development (R&D). In RRI, responsible innovation is understood as a joint endeavour of innovators and societal stakeholders, who become mutually responsive to each other in defining the 'right impacts' of the innovation in society, and in steering the innovation towards realising those impacts...
September 7, 2017: Life Sciences, Society and Policy
https://www.readbyqxmd.com/read/28860401/venous-thromboembolism-in-adult-elective-spinal-surgery-a-tertiary-centre-review-of-2181-patients
#9
H M T Fawi, K Saba, A Cunningham, S Masud, M Lewis, M Hossain, I Chopra, S Ahuja
AIMS: To evaluate the incidence of primary venous thromboembolism (VTE), epidural haematoma, surgical site infection (SSI), and 90-day mortality after elective spinal surgery, and the effect of two protocols for prophylaxis. PATIENTS AND METHODS: A total of 2181 adults underwent 2366 elective spinal procedures between January 2007 and January 2012. All patients wore anti-embolic stockings, mobilised early and were kept adequately hydrated. In addition, 29% (689) of these were given low molecular weight heparin (LMWH) while in hospital...
September 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28690031/prevalence-of-pain-in-240-non-ambulatory-children-with-severe-cerebral-palsy
#10
I Poirot, V Laudy, M Rabilloud, S Roche, T Ginhoux, B Kassaï, C Vuillerot
BACKGROUND: Several studies have given frequencies of pain in children with cerebral palsy, but comparing the findings is difficult. We aimed to estimate the prevalence of pain in non-ambulatory children with cerebral palsy and describe their characteristics by presence or absence of pain. METHODS: Data were extracted from an ongoing longitudinal national cohort following non-ambulatory children with severe cerebral palsy aged 3 to 10years over 10years. We described and compared data for the first 240 children at inclusion by presence or absence of pain...
November 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28666809/bio-based-industries-joint-undertaking-the-catalyst-for-sustainable-bio-based-economic-growth-in-europe
#11
REVIEW
Philippe Mengal, Marcel Wubbolts, Eleni Zika, Ana Ruiz, Dieter Brigitta, Agata Pieniadz, Sarah Black
This article discusses the preparation, structure and objectives of the Bio-based Industries Joint Undertaking (BBI JU). BBI JU is a public-private partnership (PPP) between the European Commission (EC) and the Bio-based Industries Consortium (BIC), the industry-led private not-for-profit organisation representing the private sectors across the bio-based industries. The model of the public-private partnership has been successful as a new approach to supporting research and innovation and de-risking investment in Europe...
June 27, 2017: New Biotechnology
https://www.readbyqxmd.com/read/28634158/stem-cell-therapy-for-enhancement-of-bone-consolidation-in-distraction-osteogenesis-a-contemporary-review-of-experimental-studies
#12
Y Yang, S Lin, B Wang, W Gu, G Li
OBJECTIVES: Distraction osteogenesis (DO) mobilises bone regenerative potential and avoids the complications of other treatments such as bone graft. The major disadvantage of DO is the length of time required for bone consolidation. Mesenchymal stem cells (MSCs) have been used to promote bone formation with some good results. METHODS: We hereby review the published literature on the use of MSCs in promoting bone consolidation during DO. RESULTS: Studies differed in animal type (mice, rabbit, dog, sheep), bone type (femur, tibia, skull), DO protocols and cell transplantation methods...
June 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/28630761/partial-proximal-tibia-fractures
#13
Michael J Raschke, Christoph Kittl, Christoph Domnick
Partial tibial plateau fractures may occur as a consequence of either valgus or varus trauma combined with a rotational and axial compression component.High-energy trauma may result in a more complex and multi-fragmented fracture pattern, which occurs predominantly in young people. Conversely, a low-energy mechanism may lead to a pure depression fracture in the older population with weaker bone density.Pre-operative classification of these fractures, by Müller AO, Schatzker or novel CT-based methods, helps to understand the fracture pattern and choose the surgical approach and treatment strategy in accordance with estimated bone mineral density and the individual history of each patient...
May 2017: EFORT open reviews
https://www.readbyqxmd.com/read/28623570/enhanced-recovery-protocols-in-total-joint-arthroplasty-a-review-of-the-literature-and-their-implementation
#14
REVIEW
A S Galbraith, E McGloughlin, J Cashman
BACKGROUND: During recent years, there has been an exponential demand for joint arthroplasty, which has coincided with the global economic recession. In response, the management of patients following arthroplasty is continuously evolving, with the average inpatient length of stay decreasing from weeks to days, and more recently, we have witnessed the development of "outpatient arthroplasty" as a novel concept which aims to address the high volume of patients. The reduction in length of stay has been made possible via implementation of "enhanced recovery programmes" encompassing each stage of the patient journey...
June 16, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28576885/osteoporosis-and-ageing-affects-the-migration-of-stem-cells-and-this-is-ameliorated-by-transfection-with-cxcr4
#15
A Sanghani-Kerai, M Coathup, S Samazideh, P Kalia, L Di Silvio, B Idowu, G Blunn
OBJECTIVES: Cellular movement and relocalisation are important for many physiologic properties. Local mesenchymal stem cells (MSCs) from injured tissues and circulating MSCs aid in fracture healing. Cytokines and chemokines such as Stromal cell-derived factor 1(SDF-1) and its receptor chemokine receptor type 4 (CXCR4) play important roles in maintaining mobilisation, trafficking and homing of stem cells from bone marrow to the site of injury. We investigated the differences in migration of MSCs from the femurs of young, adult and ovariectomised (OVX) rats and the effect of CXCR4 over-expression on their migration...
June 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/28566398/discharge-on-the-day-of-surgery-following-unicompartmental-knee-arthroplasty-within-the-united-kingdom-nhs
#16
B Bradley, S Middleton, N Davis, M Williams, M Stocker, M Hockings, D L Isaac
AIMS: Unicompartmental knee arthroplasty (UKA) has been successfully performed in the United States healthcare system on outpatients. Despite differences in healthcare structure and financial environment, we hypothesised that it would be feasible to replicate this success and perform UKA with safe day of surgery discharge within the NHS, in the United Kingdom. This has not been reported in any other United Kingdom centres. PATIENTS AND METHODS: We report our experience of implementing a pathway to allow safe day of surgery discharge following UKA...
June 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28559669/the-effect-of-spinal-position-on-sciatic-nerve-excursion-during-seated-neural-mobilisation-exercises-an-in-vivo-study-using-ultrasound-imaging
#17
Richard Ellis, Samantha Osborne, Janessa Whitfield, Priya Parmar, Wayne Hing
OBJECTIVES: Research has established that the amount of inherent tension a peripheral nerve tract is exposed to influences nerve excursion and joint range of movement (ROM). The effect that spinal posture has on sciatic nerve excursion during neural mobilisation exercises has yet to be determined. The purpose of this research was to examine the influence of different sitting positions (slump-sitting versus upright-sitting) on the amount of longitudinal sciatic nerve movement during different neural mobilisation exercises commonly used in clinical practice...
May 2017: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/28537411/-treatment-of-pelvic-avulsion-fractures-in-children-and-adolescents
#18
A Stančák, J Kautzner, T Trč, V Havlas
INTRODUCTION: Paediatric avulsion fractures of the pelvis and hip joint are rare injuries most commonly associated with a rapid muscle contraction of the respected apophysis, which is the weakest component of the growing skeleton. The chosen therapy option can be either conservative or surgical. METHODS: We present a cohort of 69 patients treated for an apophyseal avulsion fracture of the anterior superior / inferior iliac spine, the lesser and greater trochanters iliac crest and the ischial tubercle...
2017: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/28442207/tibio-talo-calcaneal-fusion-after-limb-salvage-procedures-a-retrospective-study
#19
Lukas Zak, Gerald E Wozasek
BACKGROUND: The treatment of limb threatening trauma on the distal tibia or hindfoot often results in posttraumatic osteoarthritis requiring tibiotalocalcaneal (TTC) arthrodesis. The purpose of this study was to present a case series of patients undergoing various techniques of joint fusion after bone reconstruction and deformity correction as a salvage procedure. The study should help trauma surgeons making decisions in limb salvage and deformity correction in complex lower leg and foot injuries by presenting options and treatment strategies...
July 2017: Injury
https://www.readbyqxmd.com/read/28062525/parathyroid-hormone-1-34-and-skeletal-anabolic-action-the-use-of-parathyroid-hormone-in-bone-formation
#20
L Osagie-Clouard, A Sanghani, M Coathup, T Briggs, M Bostrom, G Blunn
Intermittently administered parathyroid hormone (PTH 1-34) has been shown to promote bone formation in both human and animal studies. The hormone and its analogues stimulate both bone formation and resorption, and as such at low doses are now in clinical use for the treatment of severe osteoporosis. By varying the duration of exposure, parathyroid hormone can modulate genes leading to increased bone formation within a so-called 'anabolic window'. The osteogenic mechanisms involved are multiple, affecting the stimulation of osteoprogenitor cells, osteoblasts, osteocytes and the stem cell niche, and ultimately leading to increased osteoblast activation, reduced osteoblast apoptosis, upregulation of Wnt/β-catenin signalling, increased stem cell mobilisation, and mediation of the RANKL/OPG pathway...
January 2017: Bone & Joint Research
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