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https://www.readbyqxmd.com/read/28893014/comparison-of-continuous-femoral-nerve-block-versus-local-infiltration-analgesia-as-a-postoperative-analgesia-in-unilateral-total-knee-arthroplasty
#1
Deepika Chaubey, Hari Krishan Mahajan, Parshu Ram Chauhan, Preeti S Govind, Pushpinder Singh, Ravinder Dhanevar, Abhinav Gupta
INTRODUCTION: Local infiltration of knee joint in arthroplasty, provide postoperative analgesia and preserves motor power of quadriceps, which helps in early mobilisation, as compared to femoral nerve block which paralyses vastus medialis. AIM: To compare the quality of postoperative analgesia provided by femoral nerve block and local infiltration in unilateral Total Knee Arthroplasty (TKA). MATERIALS AND METHODS: A prospective study was conducted on 60 patients (25-65 years) of ASA I and II, which were randomly(using random number table) divided into two groups - Group 1-femoral nerve block (FNB) and Group 2-Local Infiltration Analgesia (LIA)...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28882509/clinical-benefits-of-joint-mobilisation-on-ankle-sprains-a-systematic-review-and-meta-analysis
#2
REVIEW
Ishanka Weerasekara, Peter Osmotherly, Suzanne Snodgrass, Jodie Marquez, Rutger de Zoete, Darren A Rivett
OBJECTIVE: To assess the clinical benefits of joint mobilisation on ankle sprains. DATA SOURCES: MEDLINE, MEDLINE In Process, Embase, AMED, PsycINFO, CINAHL, Cochrane library, PEDro, Scopus, SPORTDiscus and Dissertations and Thesis were searched from inception to June, 2017. STUDY SELECTION: Studies investigating humans with a grade I or II lateral or medial sprains of the ankle in any pathological state from acute to chronic, who had been treated with joint mobilisation were considered for inclusion...
September 4, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28879640/creative-tensions-mutual-responsiveness-adapted-to-private-sector-research-and-development
#3
Matti Sonck, Lotte Asveld, Laurens Landeweerd, Patricia Osseweijer
The concept of mutual responsiveness is currently based on little empirical data in the literature of Responsible Research and Innovation (RRI). This paper explores RRI's idea of mutual responsiveness in the light of recent RRI case studies on private sector research and development (R&D). In RRI, responsible innovation is understood as a joint endeavour of innovators and societal stakeholders, who become mutually responsive to each other in defining the 'right impacts' of the innovation in society, and in steering the innovation towards realising those impacts...
September 7, 2017: Life Sciences, Society and Policy
https://www.readbyqxmd.com/read/28860401/venous-thromboembolism-in-adult-elective-spinal-surgery-a-tertiary-centre-review-of-2181-patients
#4
H M T Fawi, K Saba, A Cunningham, S Masud, M Lewis, M Hossain, I Chopra, S Ahuja
AIMS: To evaluate the incidence of primary venous thromboembolism (VTE), epidural haematoma, surgical site infection (SSI), and 90-day mortality after elective spinal surgery, and the effect of two protocols for prophylaxis. PATIENTS AND METHODS: A total of 2181 adults underwent 2366 elective spinal procedures between January 2007 and January 2012. All patients wore anti-embolic stockings, mobilised early and were kept adequately hydrated. In addition, 29% (689) of these were given low molecular weight heparin (LMWH) while in hospital...
September 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28690031/prevalence-of-pain-in-240-non-ambulatory-children-with-severe-cerebral-palsy
#5
I Poirot, V Laudy, M Rabilloud, S Roche, T Ginhoux, B Kassaï, C Vuillerot
BACKGROUND: Several studies have given frequencies of pain in children with cerebral palsy, but comparing the findings is difficult. We aimed to estimate the prevalence of pain in non-ambulatory children with cerebral palsy and describe their characteristics by presence or absence of pain. METHODS: Data were extracted from an ongoing longitudinal national cohort following non-ambulatory children with severe cerebral palsy aged 3 to 10years over 10years. We described and compared data for the first 240 children at inclusion by presence or absence of pain...
July 6, 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28666809/bio-based-industries-joint-undertaking-the-catalyst-for-sustainable-bio-based-economic-growth-in-europe
#6
REVIEW
Philippe Mengal, Marcel Wubbolts, Eleni Zika, Ana Ruiz, Dieter Brigitta, Agata Pieniadz, Sarah Black
This article discusses the preparation, structure and objectives of the Bio-based Industries Joint Undertaking (BBI JU). BBI JU is a public-private partnership (PPP) between the European Commission (EC) and the Bio-based Industries Consortium (BIC), the industry-led private not-for-profit organisation representing the private sectors across the bio-based industries. The model of the public-private partnership has been successful as a new approach to supporting research and innovation and de-risking investment in Europe...
June 27, 2017: New Biotechnology
https://www.readbyqxmd.com/read/28634158/stem-cell-therapy-for-enhancement-of-bone-consolidation-in-distraction-osteogenesis-a-contemporary-review-of-experimental-studies
#7
Y Yang, S Lin, B Wang, W Gu, G Li
OBJECTIVES: Distraction osteogenesis (DO) mobilises bone regenerative potential and avoids the complications of other treatments such as bone graft. The major disadvantage of DO is the length of time required for bone consolidation. Mesenchymal stem cells (MSCs) have been used to promote bone formation with some good results. METHODS: We hereby review the published literature on the use of MSCs in promoting bone consolidation during DO. RESULTS: Studies differed in animal type (mice, rabbit, dog, sheep), bone type (femur, tibia, skull), DO protocols and cell transplantation methods...
June 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/28630761/partial-proximal-tibia-fractures
#8
Michael J Raschke, Christoph Kittl, Christoph Domnick
Partial tibial plateau fractures may occur as a consequence of either valgus or varus trauma combined with a rotational and axial compression component.High-energy trauma may result in a more complex and multi-fragmented fracture pattern, which occurs predominantly in young people. Conversely, a low-energy mechanism may lead to a pure depression fracture in the older population with weaker bone density.Pre-operative classification of these fractures, by Müller AO, Schatzker or novel CT-based methods, helps to understand the fracture pattern and choose the surgical approach and treatment strategy in accordance with estimated bone mineral density and the individual history of each patient...
May 2017: EFORT open reviews
https://www.readbyqxmd.com/read/28623570/enhanced-recovery-protocols-in-total-joint-arthroplasty-a-review-of-the-literature-and-their-implementation
#9
REVIEW
A S Galbraith, E McGloughlin, J Cashman
BACKGROUND: During recent years, there has been an exponential demand for joint arthroplasty, which has coincided with the global economic recession. In response, the management of patients following arthroplasty is continuously evolving, with the average inpatient length of stay decreasing from weeks to days, and more recently, we have witnessed the development of "outpatient arthroplasty" as a novel concept which aims to address the high volume of patients. The reduction in length of stay has been made possible via implementation of "enhanced recovery programmes" encompassing each stage of the patient journey...
June 16, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28576885/osteoporosis-and-ageing-affects-the-migration-of-stem-cells-and-this-is-ameliorated-by-transfection-with-cxcr4
#10
A Sanghani-Kerai, M Coathup, S Samazideh, P Kalia, L Di Silvio, B Idowu, G Blunn
OBJECTIVES: Cellular movement and relocalisation are important for many physiologic properties. Local mesenchymal stem cells (MSCs) from injured tissues and circulating MSCs aid in fracture healing. Cytokines and chemokines such as Stromal cell-derived factor 1(SDF-1) and its receptor chemokine receptor type 4 (CXCR4) play important roles in maintaining mobilisation, trafficking and homing of stem cells from bone marrow to the site of injury. We investigated the differences in migration of MSCs from the femurs of young, adult and ovariectomised (OVX) rats and the effect of CXCR4 over-expression on their migration...
June 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/28566398/discharge-on-the-day-of-surgery-following-unicompartmental-knee-arthroplasty-within-the-united-kingdom-nhs
#11
B Bradley, S Middleton, N Davis, M Williams, M Stocker, M Hockings, D L Isaac
AIMS: Unicompartmental knee arthroplasty (UKA) has been successfully performed in the United States healthcare system on outpatients. Despite differences in healthcare structure and financial environment, we hypothesised that it would be feasible to replicate this success and perform UKA with safe day of surgery discharge within the NHS, in the United Kingdom. This has not been reported in any other United Kingdom centres. PATIENTS AND METHODS: We report our experience of implementing a pathway to allow safe day of surgery discharge following UKA...
June 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28559669/the-effect-of-spinal-position-on-sciatic-nerve-excursion-during-seated-neural-mobilisation-exercises-an-in-vivo-study-using-ultrasound-imaging
#12
Richard Ellis, Samantha Osborne, Janessa Whitfield, Priya Parmar, Wayne Hing
OBJECTIVES: Research has established that the amount of inherent tension a peripheral nerve tract is exposed to influences nerve excursion and joint range of movement (ROM). The effect that spinal posture has on sciatic nerve excursion during neural mobilisation exercises has yet to be determined. The purpose of this research was to examine the influence of different sitting positions (slump-sitting versus upright-sitting) on the amount of longitudinal sciatic nerve movement during different neural mobilisation exercises commonly used in clinical practice...
May 2017: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/28537411/-treatment-of-pelvic-avulsion-fractures-in-children-and-adolescents
#13
A Stančák, J Kautzner, T Trč, V Havlas
INTRODUCTION: Paediatric avulsion fractures of the pelvis and hip joint are rare injuries most commonly associated with a rapid muscle contraction of the respected apophysis, which is the weakest component of the growing skeleton. The chosen therapy option can be either conservative or surgical. METHODS: We present a cohort of 69 patients treated for an apophyseal avulsion fracture of the anterior superior / inferior iliac spine, the lesser and greater trochanters iliac crest and the ischial tubercle...
2017: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/28442207/tibio-talo-calcaneal-fusion-after-limb-salvage-procedures-a-retrospective-study
#14
Lukas Zak, Gerald E Wozasek
BACKGROUND: The treatment of limb threatening trauma on the distal tibia or hindfoot often results in posttraumatic osteoarthritis requiring tibiotalocalcaneal (TTC) arthrodesis. The purpose of this study was to present a case series of patients undergoing various techniques of joint fusion after bone reconstruction and deformity correction as a salvage procedure. The study should help trauma surgeons making decisions in limb salvage and deformity correction in complex lower leg and foot injuries by presenting options and treatment strategies...
July 2017: Injury
https://www.readbyqxmd.com/read/28062525/parathyroid-hormone-1-34-and-skeletal-anabolic-action-the-use-of-parathyroid-hormone-in-bone-formation
#15
L Osagie-Clouard, A Sanghani, M Coathup, T Briggs, M Bostrom, G Blunn
Intermittently administered parathyroid hormone (PTH 1-34) has been shown to promote bone formation in both human and animal studies. The hormone and its analogues stimulate both bone formation and resorption, and as such at low doses are now in clinical use for the treatment of severe osteoporosis. By varying the duration of exposure, parathyroid hormone can modulate genes leading to increased bone formation within a so-called 'anabolic window'. The osteogenic mechanisms involved are multiple, affecting the stimulation of osteoprogenitor cells, osteoblasts, osteocytes and the stem cell niche, and ultimately leading to increased osteoblast activation, reduced osteoblast apoptosis, upregulation of Wnt/β-catenin signalling, increased stem cell mobilisation, and mediation of the RANKL/OPG pathway...
January 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/28026725/-operative-treatment-for-saddle-shaped-femoral-heads
#16
M Burian, P Dungl, J Chomiak, M Ošťádal, R Kubeš, O Schwarz
PURPOSE OF THE STUDY A saddle-shaped deformity of the femoral head has a poor prognosis due to rapid development of secondary changes. A new method of treatment by intra-articular anteromedial wedge reduction osteotomy (AWRO) of the femoral head may preserve the hip for the future. This study was designed to ascertain that this invasive technique was safe and effective and to confirm our hypothesis that AWRO significantly improved functional and radiological parameters of the hip joint. MATERIAL AND METHODS Patients who underwent AWRO between 2010 and 2013 were enrolled in this study...
2016: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/27909582/ebola-research-funding-a-systematic-analysis-1997-2015
#17
Joseph Ra Fitchett, Amos Lichtman, Damilola T Soyode, Ariel Low, Jimena Villar de Onis, Michael G Head, Rifat Atun
BACKGROUND: The latest outbreak of Ebola in West Africa overwhelmed the affected countries, with the impact on health extending far beyond Ebola-related deaths that have exceeded 11 000. The need to promptly mobilise resources to control emerging infections is widely recognized. Yet, data on research funding for emerging infections remains inadequately documented. METHODS: We defined research investment as all funding flows for Ebola and/or Marburg virus from 1997 to April 2015 whose primary purpose was to advance knowledge and new technologies to prevent or cure disease...
December 2016: Journal of Global Health
https://www.readbyqxmd.com/read/27806951/therapeutic-interventions-for-improving-self-reported-function-in-patients-with-chronic-ankle-instability-a-systematic-review
#18
REVIEW
Kyle B Kosik, Ryan S McCann, Masafumi Terada, Phillip A Gribble
OBJECTIVE: To identify which therapeutic intervention may be most effective for improving self-reported function in patients with chronic ankle instability (CAI). DESIGN: Systematic literature review. Articles were appraised using the Downs and Black Checklist by 3 reviewers. DATA SOURCES: PubMed along with CINAHL, MEDLINE and SPORTDiscus within EBSCOhost for pertinent articles from their inception through August 2016. ELIGIBILITY CRITERIA FOR SELECTED STUDIES: Articles included were required to (1) be written in English, (2) report adequate data to calculate effect sizes, (3) identify patients with CAI, (4) use some form of therapeutic intervention and (5) use a self-reported questionnaire as a main outcome measurement...
January 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/27716215/kinematic-real-time-feedback-is-more-effective-than-traditional-teaching-method-in-learning-ankle-joint-mobilisation-a-randomised-controlled-trial
#19
RANDOMIZED CONTROLLED TRIAL
Manuel González-Sánchez, Maria Ruiz-Muñoz, Ana Belén Ávila-Bolívar, Antonio I Cuesta-Vargas
BACKGROUND: To analyse the effect of real-time kinematic feedback (KRTF) when learning two ankle joint mobilisation techniques comparing the results with the traditional teaching method. METHODS: Double-blind randomized trial. SETTINGS: Faculty of Health Sciences. PARTICIPANTS: undergraduate students with no experience in manual therapy. Each student practised intensely for 90 min (45 min for each mobilisation) according to the random methodology assigned (G1: traditional method group and G2: KRTF group)...
October 6, 2016: BMC Medical Education
https://www.readbyqxmd.com/read/27676991/isokinetic-muscular-strengthening-of-upper-limb-versus-passive-movement-in-chronic-stroke-patients-randomised-controlled-trial
#20
Flavia Coroian, Jérôme Froger, H-Y Bonnin Koang, Claire Jourdan, Karima Bakhti, Marc Julia, Audrey Jaussent, Christian Hérisson, Isabelle Laffont
OBJECTIVE: The sensori-motor impairment of upper limb (UL) affects more than 50% of patients after stroke. The objective of this work was to study the efficiency of isokinetic muscle strengthening (IMS) in the chronic phase of stroke in this population. MATERIAL/PATIENTS AND METHODS: The patients underwent 6 weeks of outpatient rehabilitation, 3 days per week, combining physiotherapy (twice/day) and occupational therapy every day. The program was completed by 30 minutes elbow and wrist concentric slow speed IMS of flexor and extensor muscles, in the study group versus 30 minutes passive mobilisation of the joints carried out by the same isokinetic dynamometer in the control group...
September 2016: Annals of Physical and Rehabilitation Medicine
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