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https://www.readbyqxmd.com/read/28213848/intraoperative-blood-pressure-changes-during-cemented-versus-uncemented-bipolar-hemiarthroplasty-for-displaced-femoral-neck-fracture-a-multi-center-cohort-study-the-effect-of-bone-cement-for-bipolar-hemiarthroplasty-in-elderly-patients
#1
Shuichi Miyamoto, Junichi Nakamura, Satoshi Iida, Tomonori Shigemura, Shunji Kishida, Isao Abe, Munenori Takeshita, Yoshitada Harada, Sumihisa Orita, Seiji Ohtori
INTRODUCTION: The purpose of this study was to compare the cemented bipolar hemiarthroplasty with uncemented about the change of intraoperative blood pressure and the incidence of major complications in elderly patients with femoral neck fracture. MATERIALS AND METHODS: This multiple center prospective cohort study included only patients with acute displaced femoral neck fracture (Garden stage III or IV). All patients were treated with cemented or uncemented bipolar hemiarthroplasty using modified Hardinge or Watson-Jones approach in the lateral decubitus position...
February 17, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28163926/rapid-analgesia-for-prehospital-hip-disruption-rapid-protocol-for-feasibility-study-of-randomised-controlled-trial
#2
Jenna K Bulger, Alan Brown, Bridie A Evans, Greg Fegan, Simon Ford, Katy Guy, Sian Jones, Leigh Keen, Ashrafunnesa Khanom, Ian Pallister, Nigel Rees, Ian T Russell, Anne C Seagrove, Helen A Snooks
BACKGROUND: Adequate pain relief at the point of injury and during transport to hospital is a major challenge in all acute traumas, especially for those with hip fractures, whose injuries are difficult to immobilise and whose long-term outcomes may be adversely affected by administration of opiate analgesics. Fascia iliaca compartment block (FICB) is a procedure routinely undertaken by doctors and nurses in the emergency department for patients with hip fracture but not yet evaluated for use by paramedics at the scene of emergency calls...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28160810/non-battle-injuries-among-u-s-army-soldiers-deployed-to-afghanistan-and-iraq-2001-2013
#3
Avni A Patel, Keith G Hauret, Bonnie J Taylor, Bruce H Jones
INTRODUCTION: Many non-battle injuries among deployed soldiers are due to occupational-related tasks. Given that non-battle injuries are a significant cause of morbidity and mortality, occupational safety and health are of great concern to the military. Some of the leading causes of non-battle injuries in the military are also common in non-military occupational settings. Nationally, falls and motor-vehicle accidents are leading causes of non-fatal occupational injuries in the civilian workforce...
February 2017: Journal of Safety Research
https://www.readbyqxmd.com/read/28148657/orthopaedic-surgical-site-infection-surveillance-in-nhs-england-national-audit-of-current-practice
#4
REVIEW
E K Tissingh, A Sudlow, A Jones, J F Nolan
AIMS: The importance of accurate identification and reporting of surgical site infection (SSI) is well recognised but poorly defined. Public Health England (PHE) mandated collection of orthopaedic SSI data in 2004. Data submission is required in one of four categories (hip prosthesis, knee prosthesis, repair of neck of femur, reduction of long bone fracture) for one quarter per year. Trusts are encouraged to carry out post-discharge surveillance but this is not mandatory. Recent papers in the orthopaedic literature have highlighted the importance of SSI surveillance and the heterogeneity of surveillance methods...
February 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28144601/proximal-fifth-metatarsal-fractures-anatomy-classification-treatment-and-complications
#5
REVIEW
Chi Nok Cheung, Tun Hing Lui
CONTEXT: Fractures of proximal fifth metatarsal are one of the most common fractures of the foot. EVIDENCE ACQUISITION: A search of PubMed for studies on proximal fifth metatarsal fracture and Jones fracture focusing on the classification and management was performed. The reference list of the retrieved articles was searched for additional related studies. RESULTS: The vascular supply and soft tissue anatomy of the fifth metatarsal explains the increased risk of delayed union and non-union in fractures at the metaphyseal-diaphyseal junction...
December 2016: Archives of Trauma Research
https://www.readbyqxmd.com/read/28093944/healing-efficacy-of-fracture-targeted-gsk3%C3%AE-inhibitor-loaded-micelles-for-improved-fracture-repair
#6
Stewart A Low, Chris V Galliford, Yava L Jones-Hall, Jyoti Roy, Jiyuan Yang, Philip S Low, Jindřich Kopeček
AIM: To evaluate the fracture healing capabilities of a GSK3β inhibitor, 6-bromoindirubin-3'-oxime, coupled with an aspartic acid octapeptide in a micellar delivery system. MATERIALS & METHODS: The efficacy of the intravenously administered micelles to accelerate healing of femoral fracture in mice was evaluated. Micro-computed tomography analysis was employed to obtain bone density, total volume, relative volume, trabecular thickness and trabecular spacing. RESULTS: Both fracture bone mineral density and volume were significantly higher in the micelle treatment groups when compared with controls...
January 17, 2017: Nanomedicine
https://www.readbyqxmd.com/read/28058583/assessing-geotechnical-centrifuge-modelling-in-addressing-variably-saturated-flow-in-soil-and-fractured-rock
#7
Brendon R Jones, Luke B Brouwers, Warren D Van Tonder, Matthys A Dippenaar
The vadose zone typically comprises soil underlain by fractured rock. Often, surface water and groundwater parameters are readily available, but variably saturated flow through soil and rock are oversimplified or estimated as input for hydrological models. In this paper, a series of geotechnical centrifuge experiments are conducted to contribute to the knowledge gaps in: (i) variably saturated flow and dispersion in soil and (ii) variably saturated flow in discrete vertical and horizontal fractures. Findings from the research show that the hydraulic gradient, and not the hydraulic conductivity, is scaled for seepage flow in the geotechnical centrifuge...
January 5, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28040084/do-skeletal-muscle-mscs-in-humans-contribute-to-bone-repair-a-systematic-review
#8
Heather Owston, Peter V Giannoudis, Elena Jones
Mesenchymal stem cells (MSC) from bone marrow and periosteum are known to be heavily involved in fracture repair and bone regeneration is thought to be impaired when the surrounding skeletal muscle is damaged. Recent literature from mouse in vivo models suggest that cells originating from skeletal muscle can occupy a fracture callus during open fracture repair when periosteum is compromised. This systematic review set out to ascertain whether there are MSCs residing in human skeletal muscle and whether cells from human skeletal muscle are capable of forming bone in vitro and in vivo...
December 2016: Injury
https://www.readbyqxmd.com/read/28012704/tomosynthesis-a-new-radiologic-technique-for%C3%A2-rapid-diagnosis-of-scaphoid-fractures
#9
N Compton, L Murphy, F Lyons, J Jones, P MacMahon, J Cashman
Scaphoid fractures constitute 71% of all carpal bone fractures.(1) Early diagnosis and treatment has significant bearing on fracture union rates and better clinical outcomes. While displaced fractures can be readily seen on plain radiograph, undisplaced fractures can require advanced imaging modalities to confirm that diagnosis. Advanced imaging such as Magnetic Resonance Imaging (MRI), Computerised tomography (CT) and bone scintigraphy are routinely used for the diagnosis of scaphoid fractures but require significant radiation exposure, increased cost and can be difficult to access...
December 21, 2016: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/28002377/own-the-bone-a-system-based-intervention-improves-osteoporosis-care-after-fragility-fractures
#10
Andrew D Bunta, Beatrice J Edwards, William B Macaulay, Kyle J Jeray, Laura L Tosi, Clifford B Jones, Debra L Sietsema, John D Kaufman, Sarah A Murphy, Juhee Song, James A Goulet, Gary E Friedlaender, Marc F Swiontkowski, Douglas R Dirschl
BACKGROUND: The goal of this study was to evaluate the effectiveness of the American Orthopaedic Association's Own the Bone secondary fracture prevention program in the United States. METHODS: The objective of this quality improvement cohort study was dissemination of Own the Bone and implementation of secondary prevention (osteoporosis pharmacologic and bone mineral density [BMD] test recommendations). The main outcome measures were the number of sites implementing Own the Bone and implementation of secondary prevention, i...
December 21, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27999503/factors-affecting-the-union-of-opening-wedge-high-tibial-osteotomy-using-a-titanium-wedge-plate
#11
Husam T Nawas, Dharmpal V Vansadia, James R Heltsley, Misty Suri, Scott Montgomery, Deryk G Jones
BACKGROUND: Factors that can affect the success rate of high tibial osteotomy (HTO) include patient selection, surgical technique, type of fixation hardware, supplemental fixation, choice of bone graft, and rehabilitation protocol. The purpose of this study was to define the role of cortical hinge fractures in the risk of nonunion and collapse of opening wedge high tibial osteotomy. METHODS: A total of 60 patients (mean age, 40 years) who underwent 64 primary HTO procedures were identified from our operational database and observed at a mean follow-up of 2 years...
2016: Ochsner Journal
https://www.readbyqxmd.com/read/27995994/counteracting-bone-fragility-with-human-amniotic-mesenchymal-stem-cells
#12
Anna M Ranzoni, Michelangelo Corcelli, Kwan-Leong Hau, Jemma G Kerns, Maximilien Vanleene, Sandra Shefelbine, Gemma N Jones, Dafni Moschidou, Benan Dala-Ali, Allen E Goodship, Paolo De Coppi, Timothy R Arnett, Pascale V Guillot
The impaired maturation of bone-forming osteoblasts results in reduced bone formation and subsequent bone weakening, which leads to a number of conditions such as osteogenesis imperfecta (OI). Transplantation of human fetal mesenchymal stem cells has been proposed as skeletal anabolic therapy to enhance bone formation, but the mechanisms underlying the contribution of the donor cells to bone health are poorly understood and require further elucidation. Here, we show that intraperitoneal injection of human amniotic mesenchymal stem cells (AFSCs) into a mouse model of OI (oim mice) reduced fracture susceptibility, increased bone strength, improved bone quality and micro-architecture, normalised bone remodelling and reduced TNFα and TGFβ sigalling...
December 20, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27906924/reducing-harm-from-falls
#13
Shelley Jones, Sandy Blake, Richard Hamblin, Carmela Petagna, Carl Shuker, Alan F Merry
Serious adverse event reporting from district health boards (DHBs) brought in-hospital falls to the attention of the Health Quality & Safety Commission (the Commission) when it was incepted in 2010. In 2012, responding to the large numbers reported, the Commission began planning for a three-year programme to reduce harm from falls, initially to run 2013-2015. In this article we discuss the serious consequences of falls, and the challenges and practical considerations involved in reducing the risk of falling and the rate of falls...
December 2, 2016: New Zealand Medical Journal
https://www.readbyqxmd.com/read/27894507/do-simple-beside-lung-function-tests-predict-morbidity-after-rib-fractures
#14
Christopher A Butts, John J Brady, Sara Wilhelm, Laura Castor, Alicia Sherwood, Abby McCall, John Patch, Pamela Jones, Vicente Cortes, Adrian W Ong
BACKGROUND: We evaluated if incentive spirometry volume (ISV) and peak expiratory flow rate (PEFR) could predict acute respiratory failure (ARF) in patients with rib fractures. METHODS: Normotensive, co-operative patients were enrolled prospectively. ISV and PEFR were measured on admission, at 24 h and at 48 h by taking the best of three readings each time. The primary outcome, ARF, was defined as requiring invasive or noninvasive positive pressure ventilation...
November 19, 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27869630/a-prospective-evaluation-of-opioid-utilization-after-upper-extremity-surgical-procedures-identifying-consumption-patterns-and-determining-prescribing-guidelines
#15
REVIEW
Nayoung Kim, Jonas L Matzon, Jack Abboudi, Christopher Jones, William Kirkpatrick, Charles F Leinberry, Frederic E Liss, Kevin F Lutsky, Mark L Wang, Mitchell Maltenfort, Asif M Ilyas
BACKGROUND: Although adequate management of postoperative pain with oral analgesics is an important aspect of surgical procedures, inadvertent overprescribing can lead to excess availability of opioids in the community for potential diversion. The purpose of our study was to prospectively evaluate opioid consumption following outpatient upper-extremity surgical procedures to determine opioid utilization patterns and to develop prescribing guidelines. METHODS: All patients undergoing outpatient upper-extremity surgical procedures over a consecutive 6-month period had the following prospective data collected: patient demographic characteristics, surgical details, anesthesia type, and opioid prescription and consumption patterns...
October 19, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27856906/the-formation-of-peak-rings-in-large-impact-craters
#16
Joanna V Morgan, Sean P S Gulick, Timothy Bralower, Elise Chenot, Gail Christeson, Philippe Claeys, Charles Cockell, Gareth S Collins, Marco J L Coolen, Ludovic Ferrière, Catalina Gebhardt, Kazuhisa Goto, Heather Jones, David A Kring, Erwan Le Ber, Johanna Lofi, Xiao Long, Christopher Lowery, Claire Mellett, Rubén Ocampo-Torres, Gordon R Osinski, Ligia Perez-Cruz, Annemarie Pickersgill, Michael Poelchau, Auriol Rae, Cornelia Rasmussen, Mario Rebolledo-Vieyra, Ulrich Riller, Honami Sato, Douglas R Schmitt, Jan Smit, Sonia Tikoo, Naotaka Tomioka, Jaime Urrutia-Fucugauchi, Michael Whalen, Axel Wittmann, Kosei E Yamaguchi, William Zylberman
Large impacts provide a mechanism for resurfacing planets through mixing near-surface rocks with deeper material. Central peaks are formed from the dynamic uplift of rocks during crater formation. As crater size increases, central peaks transition to peak rings. Without samples, debate surrounds the mechanics of peak-ring formation and their depth of origin. Chicxulub is the only known impact structure on Earth with an unequivocal peak ring, but it is buried and only accessible through drilling. Expedition 364 sampled the Chicxulub peak ring, which we found was formed from uplifted, fractured, shocked, felsic basement rocks...
November 18, 2016: Science
https://www.readbyqxmd.com/read/27844118/the-cost-of-infection-in-severe-open-tibial-fractures-treated-with-a-free-flap
#17
Ulrik Kähler Olesen, Nicolas Jones Pedersen, Henrik Eckardt, Line Lykke-Meyer, Christian Thorsten Bonde, Upender Martin Singh, Martin McNally
PURPOSE: Open tibial fractures needing soft tissue cover are challenging injuries. Infection risk is high, making treatment difficult and expensive. Delayed skin closure has been shown to increase the infection rate in several studies. We aimed at calculating the direct and indirect cost of treatment, and to determine the effect of delayed skin closure on this cost. METHODS: We reviewed all records of patients treated with a free flap in our institution for an open tibial fracture from 2002 to 2013...
November 14, 2016: International Orthopaedics
https://www.readbyqxmd.com/read/27809990/the-roles-of-immune-cells-in-bone-healing-what-we-know-do-not-know-and-future-perspectives
#18
REVIEW
Jehan J El-Jawhari, Elena Jones, Peter V Giannoudis
Key events occurring during the bone healing include well-orchestrated and complex interactions between immune cells, multipotential stromal cells (MSCs), osteoblasts and osteoclasts. Through three overlapping phases of this physiological process, innate and adaptive immune cells, cytokines and chemokines have a significant role to play. The aim of the escalating immune response is to achieve an osseous healing in the shortest time and with the least complications facilitating the restoration of function. The uninterrupted progression of these biological events in conjunction with a favourable mechanical environment (stable fracture fixation) remains the hallmark of successful fracture healing...
November 2016: Injury
https://www.readbyqxmd.com/read/27800460/metacarpal-neck-fractures-a-review-of-surgical-indications-and-techniques
#19
REVIEW
Eric M Padegimas, William J Warrender, Christopher M Jones, Asif M Ilyas
CONTEXT: Hand injuries are a common emergency department presentation. Metacarpal fractures account for 40% of all hand fractures and can be seen in the setting of low or high energy trauma. The most common injury pattern is a metacarpal neck fracture. In this study, the authors aim to review the surgical indications for metacarpal neck fractures, the fixation options available along with the risk and benefits of each. EVIDENCE ACQUISITION: Literature review of the different treatment modalities for metacarpal neck fractures...
September 2016: Archives of Trauma Research
https://www.readbyqxmd.com/read/27797787/re-evaluation-of-low-intensity-pulsed-ultrasound-in-treatment-of-tibial-fractures-trust-randomized-clinical-trial
#20
Jason W Busse, Mohit Bhandari, Thomas A Einhorn, Emil Schemitsch, James D Heckman, Paul Tornetta, Kwok-Sui Leung, Diane Heels-Ansdell, Sun Makosso-Kallyth, Gregory J Della Rocca, Clifford B Jones, Gordon H Guyatt
OBJECTIVE:  To determine whether low intensity pulsed ultrasound (LIPUS), compared with sham treatment, accelerates functional recovery and radiographic healing in patients with operatively managed tibial fractures. DESIGN:  A concealed, randomized, blinded, sham controlled clinical trial with a parallel group design of 501 patients, enrolled between October 2008 and September 2012, and followed for one year. SETTING:  43 North American academic trauma centers...
October 25, 2016: BMJ: British Medical Journal
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