Ting Geng, Qigang Sun, Jingliang He, Yulu Chen, Wenhao Cheng, Jing Shen, Bin Liu, Meiqi Zhang, Sen Wang, Kadirya Asan, Mengwei Song, Qi Gao, Yizhuo Song, Ruotong Liu, Xing Liu, Yuanyuan Ding, Aixin Jing, Xiaoqing Ye, Hongyu Ren, Kaile Zeng, Ying Zhou, Boyu Zhang, Shaojie Ma, Wei Liu, Shunfang Liu, Jing Ji
CXXC5, a zinc-finger protein, is known for its role in epigenetic regulation via binding to unmethylated CpG islands in gene promoters. As a transcription factor and epigenetic regulator, CXXC5 modulates various signaling processes and acts as a key coordinator. Altered expression or activity of CXXC5 has been linked to various pathological conditions, including tumorigenesis. Despite its known role in cancer, CXXC5's function and mechanism in ovarian cancer are unclear. We analyzed multiple public databases and found that CXXC5 is highly expressed in ovarian cancer, with high expression correlating with poor patient prognosis...
April 18, 2024: Cellular Signalling