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Survivors of childhood cancer

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https://www.readbyqxmd.com/read/28538707/self-esteem-and-academic-difficulties-in-preadolescents-and-adolescents-healed-from-paediatric-leukaemia
#1
Marta Tremolada, Livia Taverna, Sabrina Bonichini, Giuseppe Basso, Marta Pillon
Adolescents with cancer may demonstrate problems in their self-esteem and schooling. This study aims to screen the preadolescents and adolescents more at risk in their self-esteem perception and schooling difficulties post-five years from the end of therapy. Twenty-five paediatric ex-patients healed from leukaemia were recruited at the Haematology-Oncologic Clinic (University of Padua). The mean age of the children was 13.64 years (Standard Deviation (SD)) = 3.08, range = 10-19 years), most were treated for acute lymphoblastic leukaemia (ALL) (84%) and relatively equally distributed by gender...
May 24, 2017: Cancers
https://www.readbyqxmd.com/read/28530852/long-term-risk-of-subsequent-malignant-neoplasms-after-treatment-of-childhood-cancer-in-the-dcog-later-study-cohort-role-of-chemotherapy
#2
Jop C Teepen, Flora E van Leeuwen, Wim J Tissing, Eline van Dulmen-den Broeder, Marry M van den Heuvel-Eibrink, Helena J van der Pal, Jacqueline J Loonen, Dorine Bresters, Birgitta Versluys, Sebastian J C M M Neggers, Monique W M Jaspers, Michael Hauptmann, Margriet van der Heiden-van der Loo, Otto Visser, Leontien C M Kremer, Cécile M Ronckers
Purpose Childhood cancer survivors (CCSs) are at increased risk for subsequent malignant neoplasms (SMNs). We evaluated the long-term risk of SMNs in a well-characterized cohort of 5-year CCSs, with a particular focus on individual chemotherapeutic agents and solid cancer risk. Methods The Dutch Childhood Cancer Oncology Group-Long-Term Effects After Childhood Cancer cohort includes 6,165 5-year CCSs diagnosed between 1963 and 2001 in the Netherlands. SMNs were identified by linkages with the Netherlands Cancer Registry, the Dutch Pathology Registry, and medical chart review...
May 22, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28530506/racial-differences-in-20-year-cardiovascular-mortality-risk-among-childhood-and-young-adult-cancer-survivors
#3
Amy M Berkman, Abenaa M Brewster, Lee W Jones, Jun Yu, J Jack Lee, S Andrew Peng, Abigail Crocker, Joann L Ater, Susan C Gilchrist
PURPOSE: Whether cardiovascular disease (CVD) risk differs according to race and cancer type among survivors of childhood or young adulthood cancers is unknown. METHODS: Data from the years 1973-2011 were analyzed using the Surveillance, Epidemiology, and End Results (SEER) registries. Cases were categorized by ICD-0-3/WHO 2008 Adolescent and Young Adult classification. CVD death was determined by ICD-10 codes for diseases of the heart, atherosclerosis, cerebrovascular diseases, or other diseases of the arteries...
May 22, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28526663/effects-of-using-child-personas-in-the-development-of-a-digital-peer-support-service-for-childhood-cancer-survivors
#4
Pontus Wärnestål, Petra Svedberg, Susanne Lindberg, Jens M Nygren
BACKGROUND: Peer support services have the potential to support children who survive cancer by handling the physical, mental, and social challenges associated with survival and return to everyday life. Involving the children themselves in the design process allows for adapting services to authentic user behaviors and goals. As there are several challenges that put critical requirements on a user-centered design process, we developed a design method based on personas adapted to the particular needs of children that promotes health and handles a sensitive design context...
May 18, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28503890/co-morbidity-and-quality-of-life-in-childhood-cancer-survivors-treated-with-proton-beam-therapy
#5
Hiroko Fukushima, Takashi Fukushima, Ryoko Suzuki, Atsushi Iwabuchi, Kyoko Hidaka, Kouji Masumoto, Ai Muroi, Tetsuya Yamamoto, Masashi Mizumoto, Hideyuki Sakurai, Ryo Sumazaki
INTRODUCTION: The ratio of childhood cancer survival achieves over 80% recently. Various adverse events among childhood cancer survivors (CCSs) has been reported. Proton beams are able to avoid unnecessary irradiation to normal/vital organs. We conducted a quality of life (QOL) study for CCSs who were treated with proton beam therapy (PBT). MATERIALS AND METHODS: We included those treated with PBT to the brain, head, or neck ≤15 years old at the University of Tsukuba Hospital from 1983 to 2011...
May 14, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28499444/a-french-national-breast-and-thyroid-cancer-screening-programme-for-survivors-of-childhood-adolescent-and-young-adult-caya-cancers-denacapst-programme
#6
Charlotte Demoor-Goldschmidt, Delphine Drui, Isabelle Doutriaux, Gérard Michel, Pascal Auquier, Agnès Dumas, Claire Berger, Valérie Bernier, Sandrine Bohrer, Pierre-Yves Bondiau, Bruno Filhon, Brice Fresneau, Claire Freycon, Dinu Stefan, Sylvie Helfre, Angela Jackson, Christine Kerr, Anne Laprie, Julie Leseur, Marc-André Mahé, Caroline Oudot, Claire Pluchard, Stéphanie Proust, Hélène Sudour-Bonnange, Céline Vigneron, Nathalie Lassau, Martin Schlumberger, Cécile Faure Conter, Florent de Vathaire
BACKGROUND: Survival of childhood, adolescent and young adult (CAYA) cancers has increased with progress in the management of the treatments and has reached more than 80% at 5 years. Nevertheless, these survivors are at great risk of second cancers and non-malignant co-morbidities in later life. DeNaCaPST is a non-interventional study whose aim is to organize a national screening for thyroid cancer and breast cancer in survivors of CAYA cancers. It will study the compliance with international recommendations, with the aim, regarding a breast screening programme, of offering for every woman living in France, at equal risk, an equal screening...
May 12, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28486495/long-term-inpatient-disease-burden-in-the-adult-life-after-childhood-cancer-in-scandinavia-aliccs-study-a-cohort-study-of-21-297-childhood-cancer-survivors
#7
Sofie de Fine Licht, Kathrine Rugbjerg, Thorgerdur Gudmundsdottir, Trine G Bonnesen, Peter Haubjerg Asdahl, Anna Sällfors Holmqvist, Laura Madanat-Harjuoja, Laufey Tryggvadottir, Finn Wesenberg, Henrik Hasle, Jeanette F Winther, Jørgen H Olsen
BACKGROUND: Survivors of childhood cancer are at increased risk for a wide range of late effects. However, no large population-based studies have included the whole range of somatic diagnoses including subgroup diagnoses and all main types of childhood cancers. Therefore, we aimed to provide the most detailed overview of the long-term risk of hospitalisation in survivors of childhood cancer. METHODS AND FINDINGS: From the national cancer registers of Denmark, Finland, Iceland, and Sweden, we identified 21,297 5-year survivors of childhood cancer diagnosed with cancer before the age of 20 years in the periods 1943-2008 in Denmark, 1971-2008 in Finland, 1955-2008 in Iceland, and 1958-2008 in Sweden...
May 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28478851/-having-cancer-was-awful-but-also-something-good-came-out-post-traumatic-growth-among-adult-survivors-of-pediatric-and-adolescent-cancer
#8
Eduardo R Zamora, Jaehee Yi, Jesmin Akter, Jonghee Kim, Echo L Warner, Anne C Kirchhoff
PURPOSE: The cancer experience may cultivate positive psychological changes that can help reduce distress during adult survivors of childhood and adolescent cancer life course. The aim of this study is to examine the positive impact of cancer in adult survivors utilizing posttraumatic growth as a guiding framework. METHOD: Participants were identified and recruited through the Utah Cancer Registry. Eligible cases were diagnosed with cancer age ≤20 years from 1973 to 2009, born in Utah, and were age ≥18 at study...
June 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28472357/thyroid-dysfunction-and-autoimmune-thyroid-diseases-among-atomic-bomb-survivors-exposed-in-childhood
#9
Misa Imaizumi, Waka Ohishi, Eiji Nakashima, Nobuko Sera, Kazuo Neriishi, Michiko Yamada, Yoshimi Tatsukawa, Ikuno Takahashi, Saeko Fujiwara, Keizo Sugino, Takao Ando, Toshiro Usa, Atsushi Kawakami, Masazumi Akahoshi, Ayumi Hida
Context: The risk of thyroid cancer increases and persists for decades among individuals exposed to ionizing radiation in childhood, while long-term effects of childhood exposure to medium to low doses radiation on thyroid dysfunction and autoimmune thyroid diseases have remained unclear. Objective: To evaluate radiation-dose responses for the prevalence of thyroid dysfunction and autoimmune thyroid disease among atomic -bomb survivors exposed in childhood. Design, Setting, and Participants: Hiroshima and Nagasaki atomic-bomb survivors who were younger than 10 years old at exposure underwent thyroid examinations at the Radiation Effects Research Foundation between 2007 and 2011, which was 62-66 years after the bombing...
May 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28463966/no-evidence-of-response-bias-in-a-population-based-childhood-cancer-survivor-questionnaire-survey-results-from-the-swiss-childhood-cancer-survivor-study
#10
Corina S Rueegg, Micòl E Gianinazzi, Gisela Michel, Marcel Zwahlen, Nicolas X von der Weid, Claudia E Kuehni
PURPOSE: This is the first study to quantify potential nonresponse bias in a childhood cancer survivor questionnaire survey. We describe early and late responders and nonresponders, and estimate nonresponse bias in a nationwide questionnaire survey of survivors. METHODS: In the Swiss Childhood Cancer Survivor Study, we compared characteristics of early responders (who answered an initial questionnaire), late responders (who answered after ≥1 reminder) and nonresponders...
2017: PloS One
https://www.readbyqxmd.com/read/28463101/healthy-cooking-classes-at-a-children-s-cancer-hospital-and-patient-survivor-summer-camps-initial-reactions-and-feasibility
#11
Margaret Raber, Karla Crawford, Joya Chandra
OBJECTIVE: Childhood cancer survivors (CCS) have been shown to practise suboptimal dietary intake and may benefit from nutrition interventions during and after treatment. Cooking classes have become popular for encouraging healthy eating behaviours in community-based programming and academic research; however, literature on teaching cooking classes in CCS is limited. The purpose of the present study was to address the development and implementation of classes for CCS based on a recently developed framework of healthy cooking behaviour...
May 2, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28458460/childbirth-and-fertility-preservation-in-childhood-and-adolescent-cancer-patients-a-second-national-survey-of-japanese-pediatric-endocrinologists
#12
Yoko Miyoshi, Tohru Yorifuji, Reiko Horikawa, Ikuko Takahashi, Keisuke Nagasaki, Hiroyuki Ishiguro, Ikuma Fujiwara, Junko Ito, Mari Oba, Hiroyuki Fujisaki, Masashi Kato, Chikako Shimizu, Tomoyasu Kato, Kimikazu Matsumoto, Haruhiko Sago, Tetsuya Takimoto, Hiroshi Okada, Nao Suzuki, Susumu Yokoya, Tsutomu Ogata, Keiichi Ozono
Although existing guidelines recommend long-term follow-up of childhood cancer survivors (CCSs), their fertility has not been fully investigated in Japan. To address this issue, we organized a working panel consisting of medical specialists in foundation hospitals. We conducted questionnaire surveys targeting pediatric endocrinologists regarding reproduction in pediatric and adolescent cancer patients in collaboration with the CCS committee of the Japanese Society for Pediatric Endocrinology (JSPE). The first questionnaire was sent to 178 directors or councilors of the JSPE, and the second was sent to those who had provided answers on their experience with childbirth or fertility preservation...
2017: Clinical Pediatric Endocrinology: Case Reports and Clinical Investigations: Official Journal of the Japanese Society for Pediatric Endocrinology
https://www.readbyqxmd.com/read/28457709/pregnancy-complications-in-survivors-of-childhood-cancer
#13
Vicki Brower
No abstract text is available yet for this article.
April 27, 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28455678/early-nutrition-and-physical-activity-interventions-in-childhood-cancer-survivors
#14
REVIEW
Fang Fang Zhang, Michael J Kelly, Aviva Must
PURPOSE OF REVIEW: Childhood cancer survivors experience excessive weight gain early in treatment. Lifestyle interventions need to be initiated early in cancer care to prevent the early onset of obesity and cardiovascular disease (CVD). We reviewed the existing literature on early lifestyle interventions in childhood cancer survivors and consider implications for clinical care. RECENT FINDINGS: Few lifestyle interventions focus on improving nutrition in childhood cancer survivors...
April 28, 2017: Current Obesity Reports
https://www.readbyqxmd.com/read/28453181/understanding-predictors-of-continued-long-term-pediatric-cancer-care-across-the-region-a-report-from-the-consortium-for-new-england-childhood-cancer-survivors
#15
Jennifer J G Welch, Lisa B Kenney, Priya Hirway, G Naheed Usmani, Nina Kadan-Lottick, Satkiran S Grewal, Mary Huang, Heather Bradeen, Jeremy Ader, Lisa Diller, Cindy L Schwartz
BACKGROUND: Many survivors of childhood cancer do not receive recommended longitudinal oncology care. Factors present at the time of childhood cancer diagnosis may identify patients who are vulnerable to poor adherence to follow-up. METHODS: This cohort of survivors of acute lymphoblastic leukemia (ALL) diagnosed from 1996 to 1999 at seven Consortium for New England Childhood Cancer Survivors institutions was evaluated for attendance at oncology clinics at 5 and 10 years from diagnosis...
April 28, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28452142/impact-of-sleep-fatigue-and-systemic-inflammation-on-neurocognitive-and-behavioral-outcomes-in-long-term-survivors-of-childhood-acute-lymphoblastic-leukemia
#16
Yin Ting Cheung, Tara M Brinkman, Daniel A Mulrooney, Yasmin Mzayek, Wei Liu, Pia Banerjee, Angela Panoskaltsis-Mortari, Deokumar Srivastava, Ching-Hon Pui, Leslie L Robison, Melissa M Hudson, Kevin R Krull
BACKGROUND: Long-term survivors of childhood acute lymphoblastic leukemia (ALL) are at risk for neurocognitive impairment, which may be associated with fatigue, sleep problems, systemic inflammation, and oxidative stress. We examined these associations among survivors of childhood ALL treated with chemotherapy only. METHODS: Survivors of childhood ALL (male, n = 35 and female, n = 35; mean age, 14.3 years [standard deviation, 4.7 years] and mean years from diagnosis, 7...
April 27, 2017: Cancer
https://www.readbyqxmd.com/read/28451645/frailty-and-quality-of-life-in-adult-survivors-of-childhood-cancer
#17
Kirsten K Ness, Carrie R Howell, Kari L Bjornard
INTRODUCTION: Adult survivors of childhood cancer are at risk for frailty, a state of diminished physiologic reserve, typically seen in older adults, associated with morbidity and mortality. They are also at risk for poor quality of life. This review explores potential associations between frailty and quality of life and proposes potential interventions that may prevent or remediate frail health. AREAS COVERED AND LITERATURE SEARCH: A literature search using MEDLINE and EMBASE was undertaken using key words: childhood cancer survivors and each of the following: frailty, physical performance, emotional health, and quality of life...
2017: Expert Review of Quality of Life in Cancer Care
https://www.readbyqxmd.com/read/28434047/late-renal-toxicity-of-treatment-for-childhood-malignancy-risk-factors-long-term-outcomes-and-surveillance
#18
Roderick Skinner
Chronic glomerular and tubular nephrotoxicity is reported in 20-50% and 20-25%, respectively, of children and adolescents treated with ifosfamide and 60-80% and 10-30%, respectively, of those given cisplatin. Up to 20% of children display evidence of chronic glomerular damage after unilateral nephrectomy for a renal tumour. Overall, childhood cancer survivors have a ninefold higher risk of developing renal failure compared with their siblings. Such chronic nephrotoxicity may have multiple causes, including chemotherapy, radiotherapy exposure to kidneys, renal surgery, supportive care drugs and tumour-related factors...
April 22, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28425203/educational-and-career-goal-attainments-in-young-adult-childhood-cancer-survivors
#19
Lisa Bashore, Emma Breyer
PURPOSE: Examine the educational and career outcomes of young adult childhood cancer survivors. DESIGN AND METHODS: Descriptive study design using a survey sent to 336 survivors. Quantitative and qualitative data were analyzed separately. RESULTS: Only 50 completed surveys were returned. Having a central nervous system tumor and radiation were associated with physical impairments. Four themes also emerged: future as medical professionals, dreams fallen short, peer relationships, and positive outlook on life...
April 2017: Journal for Specialists in Pediatric Nursing: JSPN
https://www.readbyqxmd.com/read/28419648/the-role-of-body-image-dissatisfaction-in-the-association-between-treatment-related-scarring-or-disfigurement-and-psychological-distress-in-adult-survivors-of-childhood-cancer
#20
Stefanie C Vuotto, Rohit P Ojha, Chenghong Li, Cara Kimberg, James L Klosky, Kevin R Krull, Deo Kumar Srivastava, Leslie L Robison, Melissa M Hudson, Tara M Brinkman
PURPOSE: To examine the potential mediating role of body image dissatisfaction on the association between treatment-related scarring/disfigurement and psychological distress in adult survivors of childhood cancer. METHODS: Participants included 1,714 adult survivors of childhood cancer (mean[SD] age at evaluation = 32.4[8.0] years, time since diagnosis = 24.1[8.1] years) enrolled in the St. Jude Lifetime Cohort Study. Survivors completed measures of body image, emotional distress and posttraumatic stress symptoms (PTSS)...
April 18, 2017: Psycho-oncology
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