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https://www.readbyqxmd.com/read/28813496/uneven-distribution-of-enamel-dentine-and-cementum-in-cheek-teeth-of-domestic-horses-equus-caballus-a-micro-computed-tomography-study
#1
Lauritz Martin Englisch, Kathrin Kostrzewa, Susan Kopke, Klaus Failing, Carsten Staszyk
BACKGROUND: Hypsodont equine cheek teeth possess large dental crowns, resting partly in the bony alveolus. Over a horse's life cheek teeth erupt continuously to compensate for occlusal wear of 3-4 mm per year. Parts of the crown initially resting in the bony alveolus become progressively exposed at the occlusal surface with time. Hitherto, it is unclear whether the typical structure of the equine occlusal surface, composed of a complex arrangement of enamel, dentin and cementum, remains constant or undergoes structural changes with age...
2017: PloS One
https://www.readbyqxmd.com/read/28811640/a-reciprocal-interaction-between-%C3%AE-catenin-and-osterix-in-cementogenesis
#2
Hwajung Choi, Tak-Heun Kim, Siqin Yang, Jeong-Chae Lee, Hyung-Keun You, Eui-Sic Cho
Although accumulating evidence indicates that both β-catenin and osterix (Osx) are essential for bone and tooth development, few studies have investigated the interaction of these two key proteins in the context of cementogenesis. In this study, we used transgenic mice with constitutively active β-catenin and inactive Osx in the dental mesenchyme to address this question. We found that cementoblasts with constitutively active β-catenin require Osx to produce excessive cellular cementum, and that ablation of Osx prevents this abnormal accumulation...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28771955/mineral-features-of-connective-dental-hard-tissues-in-hypoplastic-amelogenesis-imperfecta
#3
Rym Kammoun, Catherine Behets, Lamia Mansour, Sonia Ghoul-Mazgar
To explore the mineral features of dentin and cementum in hypoplastic AI teeth MATERIALS AND METHODS: Forty four (44) teeth cleaned and free of caries were used: 20 control and 24 affected by hypoplastic amelogenesis imperfecta. Thirty-two teeth were studied by pQCT, cut in sections and analysed under microradiography, polarized light microscopy and confocal Raman spectroscopy. Eight teeth were observed under scanning electron microscope. Four teeth were used for an X-ray diffraction. The mineral density data were analysed statistically with the Mann-Whitney U test, using GraphPad InStat Software RESULTS: Both coronal and radicular dentin were less mineralized in AI teeth when compared to control (respectively 6...
August 3, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28766808/investigation-of-the-regenerative-potential-of-necrotic-mature-teeth-following-different-revascularisation-protocols
#4
Sarah Hossam Fahmy, Ehab El Sayed Hassanien, Mohamed Mokhtar Nagy, Kariem Mostafa El Batouty, Mohamed Mekhemar, Karim Fawzy El Sayed, El Hassan Hassanein, Jörg Wiltfang, Christof Dörfer
This study aimed to assess the revascularisation potential of necrotic mature teeth in a dog model following different protocols. Periapical infection was induced in 54 mature premolars. Teeth were distributed into seven groups: (1) Double-antibiotic-paste/Blood clot, (2) Ciprofloxacin/collagen, (3) Double-antibiotic-paste/Collagen, (4) Modified Tri-antibiotic-paste /collagen, (5) Ciprofloxacin/Gelfoam, (6) Double-antibiotic-paste/Gelfoam, and (7) Modified Triantibiotic- paste/Gelfoam. Positive and negative controls included infected and healthy teeth, respectively, (n = 12 roots/group)...
August 2, 2017: Australian Endodontic Journal: the Journal of the Australian Society of Endodontology Inc
https://www.readbyqxmd.com/read/28764948/effects-of-the-incorporation-of-%C3%AE%C2%B5-aminocaproic-acid-chitosan-particles-to-fibrin-on-cementoblast-differentiation-and-cementum-regeneration
#5
Chan Ho Park, Joung-Hwan Oh, Hong-Moon Jung, Yoonnyoung Choi, Saeed Rahman, Sungtae Kim, Tae-Il Kim, Hong-In Shin, Yun-Sil Lee, Frank H Yu, Jeong-Hwa Baek, Hyun-Mo Ryoo, Kyung Mi Woo
Cementum formation on the exposed tooth-root surface is a critical process in periodontal regeneration. Although various therapeutic approaches have been developed, regeneration of integrated and functional periodontal complexes is still wanting. Here, we found that the OCCM30 cementoblasts cultured on fibrin matrix express substantial levels of matrix proteinases, leading to the degradation of fibrin and the apoptosis of OCCM30 cells, which was reversed upon treatment with a proteinase inhibitor, ε-aminocaproic acid (ACA)...
July 29, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28764922/tissue-specific-mineralization-defects-in-the-periodontium-of-the-hyp-mouse-model-of-x-linked-hypophosphatemia
#6
Benjamin R Coyac, Guillaume Falgayrac, Brigitte Baroukh, Lotfi Slimani, Jérémy Sadoine, Guillaume Penel, Martin Biosse-Duplan, Thorsten Schinke, Agnès Linglart, Marc D McKee, Catherine Chaussain, Claire Bardet
X-linked hypophosphatemia (XLH) is a dento-osseous disorder caused by inactivating mutations in the PHEX gene, leading to renal phosphate wasting and hypophosphatemia, and impaired mineralization of bones and teeth. In the oral cavity, recent reports suggest a higher susceptibility of XLH patients to periodontitis, where patients present with impaired tooth cementum - a bone-like tissue involved in tooth attachment to the jaw bones and post-eruption tooth positioning - and a higher frequency of intrabony defects...
July 29, 2017: Bone
https://www.readbyqxmd.com/read/28762889/orthodontic-management-of-a-dental-concrescence-a-case-report
#7
Nicky David Stanford, Sara Hosni, Tim Morris
Dental concrescence is a rare dental abnormality resulting in the joining of two teeth at the level of the cementum. This is the first reported case of the orthodontic management of a dental concrescence and the options for patient treatment are discussed. In this case, a compromised occlusal result was accepted with restorative masking of the affected teeth.
August 1, 2017: Journal of Orthodontics
https://www.readbyqxmd.com/read/28761940/management-of-ankylotic-root-resorption-following-dental-trauma-a-short-review-and-proposal-of-a-treatment-protocol
#8
Shaul Lin, Malka Ashkenazi, Munir Karawan, Sorin T Teich, Zvi Gutmacher
Ankylotic root resorption is a serious complication following traumatic dental injuries. The aetiology of root resorption includes acute injury to the cementum and periodontal ligament, and subsequent biological processes that propagate the harm. The aim of the present paper is to present a structured treatment protocol for teeth that have experienced trauma and are at risk of developing ankylotic root resorption, followed by a decoronation protocol for situations in which ankylotic root resorption developed...
July 31, 2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28758304/subgingival-debridement-end-point-methods-and-how-often
#9
REVIEW
Isabelle Laleman, Simone Cortellini, Senne De Winter, Esteban Rodriguez Herrero, Christel Dekeyser, Marc Quirynen, Wim Teughels
Subgingival debridement is the part of nonsurgical therapy which aims to remove the biofilm without intentionally removing the cementum or subgingival calculus. The objective of this review was to describe the end point of this therapy, the different methods used and how often it should be carried out. The literature shows that several methods are currently available for subgingival debridement, namely hand instrumentation, (ultra)sonic instrumentation, laser, photodynamic therapy and air-polishing. None of these methods seems superior to any other regarding clinical benefits or microbiological differences...
October 2017: Periodontology 2000
https://www.readbyqxmd.com/read/28755493/osteoinductive-porous-biphasic-calcium-phosphate-ceramic-as-an-alternative-to-autogenous-bone-grafting-in-the-treatment-of-mandibular-bone-critical-size-defects
#10
Paula Sanches Santos, Tania Mary Cestari, Jéssica Botto Paulin, Renato Martins, Caroline Andrade Rocha, Ricardo Vinícius Nunes Arantes, Bruna Carolina Costa, Cássio Morilla Dos Santos, Gerson Francisco Assis, Rumio Taga
The bone-induction capacity of a porous biphasic calcium phosphate (pBCP) using heterotopic implantation in mouse (mHI-model) and its efficacy as substitute for autograft in mandibular critical-size defect in rabbit (rabMCSD-model) was investigated. In mHI-model, pBCP was implanted into the thigh muscles and bone formation was histomorphometrically and immunohistochemically evaluated. In rabMCSD-model, 13 mm bone defects were treated with pBCP or autograft and bone repair comparatively evaluated by radiographic and histomorphometric methods...
July 29, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28727472/relieving-dry-mouth-varying-levels-of-ph-found-in-bottled-water
#11
Bailey Jean Fisher, Angela Spencer, Van Haywood, Gayathri Konchady
It is estimated that 30% of people older than 60 years suffer from hyposalivation or dry mouth. Drinking water frequently has been recommended as a safe, non-pharmacologic way to combat hyposalivation. The saliva in patients with dry mouth is acidic. Beverages consumed daily may have an erosive potential on teeth. The pH and the mineral content of the beverage determine its erosive potential. An acidic beverage, therefore, may have harmful effects on mineralized tooth structures, causing erosion of enamel, dentin, and cementum...
July 2017: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/28717633/cementum-and-dentin-repair-following-root-damage-caused-by-the-insertion-of-self-tapping-and-self-drilling-miniscrews
#12
Majid Ghanbarzadeh, Farzin Heravi, Reihaneh Abrishamchi, Hooman Shafaee, Narges Ghazi, Parya Heravi, Hamid Ghanbarzadeh
OBJECTIVE: The aim of this study was to evaluate the histological responses of cementum, root dentin, and pulp following intentional root injuries caused via self-tapping and self-drilling miniscrews. MATERIALS AND METHODS: Fourteen patients (with a mean age of 15.7 years and age range of 14-18 years) who were scheduled for the extraction of all four first premolars as part of their orthodontic treatment plan participated in this study. The roots of the right and the left quadrants' first premolars were designedly injured using self-tapping miniscrews and self-drilling miniscrews, respectively...
July 2017: Journal of Orthodontic Science
https://www.readbyqxmd.com/read/28692806/microrna-155-3p-mediates-tnf-%C3%AE-inhibited-cementoblast-differentiation
#13
X Wang, H Sun, H Liao, C Wang, C Jiang, Y Zhang, Z Cao
Periodontitis is a prevalent and chronic inflammatory disease that is interrelated with systemic health. Periodontitis can be promoted by tumor necrosis factor α (TNF-α). Cementum, a vital part of the periodontium, is a bone-like mineralized tissue that is produced by cementoblasts. Our laboratory previously revealed that TNF-α inhibits cementoblast differentiation and mineralization. However, how TNF-α modulates cementoblast differentiation and mineralization remains largely unknown. MicroRNA-155 (miR-155) is induced and regulates TNF-α-inhibited osteogenic differentiation...
July 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28691462/odontomas-review-of-the-literature-and-case-reports
#14
C Gervasoni, A Tronchet, S Spotti, S Valsecchi, V Palazzolo, S Riccio, A D Aiuto, L Azzi, A Di Francesco
Odontomas are one of the most common Odontogenic Tumors of the jaw. The exact etiology of odontomas is unknown. Histologically they are composed of various formations of dental tissue (enamel, dentin, cementum and sometimes pulp). In the WHO classification, they are divided into complex odontoma and compound odontoma. Clinically, odontomas are generally asymptomatic and only in rare cases cause swelling, pain, suppuration or bony expansion. Radiologically, the tumor is initially lucent, but with time, it develops small calcifications, which eventually coalesce to form a radiodense lesion with a lucent rim...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28688217/yes-associated-protein-1-promotes-the-differentiation-and-mineralization-of-cementoblast
#15
Beining Yang, Hualing Sun, Fangfang Song, Yanru Wu, Jiawei Wang
Yes-associated protein 1 (YAP1) transcriptional coactivator is a mediator of mechanosensitive signaling. Cementum, which covers the tooth root surface, continuously senses external mechanical stimulation. Cementoblasts are responsible for the mineralization and maturation of the cementum. However, the effect of YAP1 on cementoblast differentiation remains largely unknown. In this study, we initially demonstrated that YAP1 overexpression enhanced the mineralization ability of cementoblasts. YAP1 upregulated the mRNA and protein expression of several cementogenesis markers, such as alkaline phosphatase (ALP), runt-related transcription factor 2 (Runx2), osteocalcin (OCN), and dentin matrix acidic phosphoprotein 1 (DMP1)...
July 8, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28688184/root-surface-temperature-variation-during-mechanical-removal-of-root-canal-filling-material-an-in-vitro-study
#16
Martín García-Cuerva, Lucía Horvath, Laura Pinasco, Verónica Ciparelli, Ariel Gualtieri, Ana C Casadoumecq, Pablo Rodríguez, Carlos Gonzalez-Zanotto
The aim of this study was to analyze in vitro temperature changes on the outer surface of the dental root during mechanical filling removal procedures. Thirty recently extracted single-rooted lower premolars were cut transversally at 16 mm from the apex in order to standardize sample length. Endodontic treatment was performed on them. The filling material was subsequently removed using Gates Glidden (G1, G2, G3); Peeso (P1, P2, P3) and PostecPlus FRC (FRC) reamers while temperatures were measured on the outer surface using a digital device with thermocouple at 0, 2, 4, 6, 8, 10 and 15 seconds...
April 2017: Acta Odontológica Latinoamericana: AOL
https://www.readbyqxmd.com/read/28681425/localization-of-relm-%C3%AE-fizz2-is-associated-with-cementum-formation
#17
Akihiro Hosoya, Akira Takahama, Hiroaki Nakamura
Resistin-like molecule-β/found in inflammatory zone 2 (RELM-β/FIZZ2) is a cysteine-rich secretory protein that is localized in the epithelium of the gastrointestinal tract and lung alveoli. Previous reports have suggested that this protein regulates glucose metabolism and inflammation. In the present study, to analyze the involvement of RELM-β/FIZZ2 in tooth development, we immunohistochemically examined the localization of RELM-β/FIZZ2 in tooth germs of embryonic days (E) 15-20 and postnatal days (P) 7-42 rats...
July 6, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28677589/regeneration-of-periapical-lesions-post-endodontic-treatment-and-periapical-surgeries-in-experimental-animals-utilizing-thermo-responsive-nano-%C3%AE-tricalcium-phosphate-chitosan-hydrogel-a-proof-of-concept
#18
Wafa I Abdel-Fattah, Salma Hassan El Ashry, Ghareib W Ali, Mohamed Aiad Abdel Hamid, Amina Gamal El-Din, Bassma El-Ashry
Using phosphate nanoparticles/polymeric hydrogels presents an interesting approach, especially concerning the reduced particle migration and enhanced biocompatibility. The current work aims to achieve a proof of concept for the development of a thermo-sensitive nano β-tricalcium phosphate (β-TCP)/chitosan (Cs)/glycerophosphate (Gl)/glyoxal (Gly) hydrogel to be applied in periapical surgeries post endodontic treatment. Physicochemical characterization using x-ray powder diffraction, Fourier transform infrared, TEM and SEM was performed...
July 5, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28665752/signaling-pathways-critical-for-tooth-root-formation
#19
J Wang, J Q Feng
Tooth is made of an enamel-covered crown and a cementum-covered root. Studies on crown dentin formation have been a major focus in tooth development for several decades. Interestingly, the population prevalence for genetic short root anomaly (SRA) with no apparent defects in crown is close to 1.3%. Furthermore, people with SRA itself are predisposed to root resorption during orthodontic treatment. The discovery of the unique role of Nfic (nuclear factor I C; a transcriptional factor) in controlling root but not crown dentin formation points to a new concept: tooth crown and root have different control mechanisms...
June 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28654783/fibulins-and-matrilins-are-novel-structural-components-of-the-periodontium-in-the-mouse
#20
Andrea Schubert, Boris Schminke, Nicolai Miosge
Periodontitis refers to inflammatory disease of the periodontal structures (the gingiva, dental cementum, periodontal ligament (PDL) and alveolar bone) that ultimately leads to their destruction. Whereas collagens are well-examined main components of the periodontium, little is known about the other structural proteins that make up this tissue. The aim of this study was to identify new extracellular matrix (ECM) components, including fibulins and matrilins, in the periodontium of mice. After sacrificing 14 mice (Sv/129 strain), jaws were prepared...
June 13, 2017: Archives of Oral Biology
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