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https://www.readbyqxmd.com/read/28636235/stem-cell-based-tooth-and-periodontal-regeneration
#1
Lei Hu, Yi Liu, Songlin Wang
Currently regeneration of tooth and periodontal damage still remains great challenge. Stem cell-based tissue engineering raised novel therapeutic strategies for tooth and periodontal repair. Stem cells for tooth and periodontal regeneration include dental pulp stem cells (DPSCs), periodontal ligament stem cells (PDLSCs), stem cells from the dental apical papilla (SCAPs), and stem cells from human exfoliated deciduous teeth (SHEDs), dental follicle stem cells (DFSCs), dental epithelial stem cells (DESCs), bone marrow mesenchymal stem cells (BMMSCs), adipose-derived stem cells (ADSCs), embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs)...
June 21, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28629602/management-of-dentin-hypersensitivity-by-practitioners-in-the-national-dental-practice-based-research-network
#2
Dorota T Kopycka-Kedzierawski, Cyril Meyerowitz, Mark S Litaker, Marc W Heft, Nirmala Tasgaonkar, Marianne R Day, Andretta Porter-Williams, Valeria V Gordan, Robin L Yardic, Timothy M Lawhorn, Gregg H Gilbert
BACKGROUND: Dentin hypersensitivity (DH) is a condition commonly encountered in clinical dental practice. The authors conduct a study to identify the treatments recommended to manage DH among dentists in the United States. METHODS: The authors conducted a multicenter study of 1,862 patients with DH who received a diagnosis and were treated by 171 dentists with the National Dental Practice-Based Research Network. RESULTS: The most common treatment recommended was desensitizing over-the-counter (OTC) potassium nitrate toothpaste (alone or in combination with other treatments) for 924 of 1,862 patients (50%)...
June 16, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28629008/multi-walled-carbon-nanotubes-graphene-oxide-hybrid-and-nanohydroxyapatite-composite-a-novel-coating-to-prevent-dentin-erosion
#3
Sídnei Nahorny, Hudson Zanin, Vinie Abreu Christino, Fernanda Roberta Marciano, Anderson Oliveira Lobo, Luís Eduardo Silva Soares
To date is emergent the development of novel coatings to protect erosion, especially to preventive dentistry and restorative dentistry. Here, for the first time we report the effectiveness of multi-walled carbon nanotube/graphene oxide hybrid carbon-base material (MWCNTO-GO) combined with nanohydroxyapatite (nHAp) as a protective coating for dentin erosion. Fourier transform Raman spectroscopy (FT-Raman), scanning electron (SEM), and transmission electron (TEM) microscopy were used to investigated the coatings and the effect of acidulated phosphate fluoride gel (APF) treatment on bovine teeth root dentin before and after erosion...
October 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28628822/spatial-distribution-of-trace-element-ca-normalized-ratios-in-primary-and-permanent-human-tooth-enamel
#4
Théo Tacail, Lenka Kovačiková, Jaroslav Brůžek, Vincent Balter
The trace elements distribution embedded in tooth enamel offers a means to study exposure of toxic metals and allows the reconstruction of dietary behaviors. The quantification of most of the elements with a spatial high resolution (~50μm) is routinely achieved using laser ablation inductively coupled plasma mass spectrometry (LA-ICPMS). However, the lack of a comprehensive framework of trace elements distribution in enamel jeopardizes any endorsed sampling strategy using LA-ICPMS. The present work is an effort to improve our knowledge on this issue...
June 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28626288/assessment-of-radicular-dentin-permeability-after-irradiation-with-co2-laser-and-endodontic-irrigation-treatments-with-thermal-imaging
#5
Heajin Cho, Robert C Lee, Kenneth H Chan, Daniel Fried
Previous studies have demonstrated that the permeability changes due to the surface modification of dentin can be quantified via thermal imaging during dehydration. The CO2 laser has been shown to remove the smear layer and disinfect root canals. Moreover, thermal modification via CO2 laser irradiation can be used to convert dentin into a highly mineralized enamel-like mineral. The purpose of this study is to evaluate the radicular dentin surface modification after CO2 laser irradiation by measuring the permeability with thermal imaging...
January 28, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28626204/intrapulpal-temperature-changes-during-curing-of-different-bulk-fill-restorative-materials
#6
Elif Yasa, Cigdem Atalayin, Gamze Karacolak, Tugrul Sari, L Sebnem Turkun
The aim of this study was to evaluate the intrapulpal temperature changes during the curing of different bulk-fill restorative materials. Ten mandibular molar teeth were selected and occlusal surfaces were removed to obtain a standard 0.5 mm occlusal dentin thickness. Five bulk-fill restorative materials and a conventional resin composite (control) were applied. The intrapulpal temperature changes during the curing of these materials were determined by a device simulating pulpal blood microcirculation. The difference between the initial and maximum temperature values (Δt), was recorded...
June 15, 2017: Dental Materials Journal
https://www.readbyqxmd.com/read/28621833/multiple-external-cervical-root-resorptions-after-home-bleaching-treatment-with-22-carbamide-peroxide
#7
Glauco Rodrigues Velloso, Marcos Motta de Freitas, Adriana Terezinha Neves Novellino Alves, Alan Roger Santos Silva, Eliane Dos Santos Porto Barboza, Vittorio Moraschini
Invasive multiple cervical root resorptions after vital tooth bleaching is a rare condition. The aim of this article is to present a case of multiple external cervical root resorptions (ECRR) after a misguided home whitening treatment. A 34-year-old male patient presented with slight sensitivity and mobility in several teeth. Despite the manufacturer's recommendations, the patient used a 22% carbamide peroxide-based tooth bleaching gel at home for 4 consecutive days, at night, on the upper and lower arches...
June 16, 2017: Australian Dental Journal
https://www.readbyqxmd.com/read/28621288/photodvnamic-therapy-in-endodontics
#8
Zahed Mohammadi, Hamid Jafarzadeh, Sousan Shalavi, Jun-Ichiro Kinoshita
Commonly used irrigants do not always eradicate the entire microbial flora in infected root canals. Therefore, several other strategies, such as photodynamic therapy (PDT) have been developed. Photoactivated disinfection is based on the interaction of a photosensitive antibacterial agent and a light source. It uses a nontoxic dye named photosensitizer (PS) and low-intensity visible light. In oxygen presentation, these combine to produce some cytotoxic species. The PS molecules attach to bacteria membrane. Irradiation with a specific wavelength of the light may lead to the production of singlet oxygen, resulting in rupture of the microbial cell wall...
June 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28621281/evaluation-of-microleakage-in-class-v-restorations-with-three-different-adhesive-systems
#9
Shamim Anjum, Azar Malik, Satish Sharma
AIM: This study was conducted to evaluate the microleakage of class V cavities restored with composite resin and different adhesive systems. MATERIALS AND METHODS: In this experimental epidemiological investigation, a total of 75 freshly extracted human teeth were collected. The teeth were randomly divided into three groups (n = 25). Three different intermediate adhesive materials (Clearfil SE Bond, Single Bond, and Xeno III) were used for each group. RESULTS: On testing without the application of occlusal load, the maximum microleakage was seen for group III (Xeno III) followed by group I (Clearfil SE) and then group II (Single Bond)...
June 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28621270/influence-of-hand-instrumentation-and-ultrasonic-scaling-on-the-microleakage-of-various-cervical-restorations-an-in-vitro-study
#10
Bita Rohani, Mehrdad Barekatain, Shirin Z Farhad, Navid Haghayegh
INTRODUCTION: In cervical lesions, various restorative materials can be inserted, which can be affected by the application of periodontal scalers. This study evaluated and compared the marginal seal of class V glass ionomer, composite resin, and amalgam restorations after subjecting them to hand instrumentation and ultrasonic scaling. MATERIALS AND METHODS: In this experimental study, 30 sound human first premolars were selected. In each tooth, buccal and lingual cavities (4 mm mesiodistal width, 3 mm occlusogingival height, and 2 mm depth) were made...
June 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28620631/the-effect-of-titanium-tetrafluoride-and-sodium-hypochlorite-on-the-shear-bond-strength-of-methacrylate-and-silorane-based-composite-resins-an-in-vitro-study
#11
Farahnaz Sharafeddin, Fatemeh Koohpeima, Nader Razazan
STATEMENT OF THE PROBLEM: The bond strength of composites with different adhesive systems with dentin is an important factor in long term durability of composite restorations. The effect of titanium tetrafluoride (TiF4) as anti caries agent and sodium hypochlorite (NaOCl) as disinfectant on the shear bond of nanofilled and silorane based composite resins have not been investigated in previous studies. PURPOSE: This study was conducted to determine bond strength between dentin and two composite systems, by means of shear bond test using TiF4 and NaOCl...
June 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28620244/specific-ablation-of-mouse-fam20c-in-cells-expressing-type-i-collagen-leads-to-skeletal-defects-and-hypophosphatemia
#12
Peihong Liu, Su Ma, Hua Zhang, Chao Liu, Yongbo Lu, Li Chen, Chunlin Qin
FAM20C mutations in humans cause Raine syndrome and our previous studies showed that global inactivation of mouse Fam20C led to bone and dental defects. By crossbreeding 2.3  kb Col 1a1-Cre mice with Fam20C (flox/flox) mice, we created 2.3  kb Col 1a1-Cre;Fam20C (foxl/flox) (cKO) mice, in which Fam20C was inactivated in cells expressing Type I collagen. This study showed that the long bones of cKO mice were shorter and had a lower level of mineralization compared to the normal mice. The collagen fibrils in Fam20C-deficient bone were disorganized and thicker while the growth plate cartilage in cKO mice was disorganized and wider compared to the normal mice...
June 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28615078/characterisation-of-roseomonas-mucosa-isolated-from-the-root-canal-of-an-infected-tooth
#13
Nina Diesendorf, Stefanie Köhler, Walter Geißdörfer, Tanja Grobecker-Karl, Matthias Karl, Andreas Burkovski
OBJECTIVE: The genus Roseomonas comprises a group of pink-pigmented, slow-growing, aerobic, non-fermentative Gram-negative bacteria, which have been isolated from environmental sources such as water and soil, but are also associated with human infections. In the study presented here, Roseomonas mucosa was identified for the first time as part of the endodontic microbiota of an infected root canal and characterised in respect to growth, antibiotic susceptibility and biofilm formation. RESULTS: The isolated R...
June 14, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28613154/seal-or-varnish-a-randomised-controlled-trial-to-determine-the-relative-cost-and-effectiveness-of-pit-and-fissure-sealant-and-fluoride-varnish-in-preventing-dental-decay
#14
Ivor Gordon Chestnutt, Simon Hutchings, Rebecca Playle, Sarah Morgan-Trimmer, Deborah Fitzsimmons, Nadine Aawar, Lianna Angel, Sharron Derrick, Cheney Drew, Ceri Hoddell, Kerenza Hood, Ioan Humphreys, Nigel Kirby, Tin Man Mandy Lau, Catherine Lisles, Maria Zeta Morgan, Simon Murphy, Jacqueline Nuttall, Kateryna Onishchenko, Ceri Phillips, Timothy Pickles, Charlotte Scoble, Julia Townson, Beverley Withers, Barbara Lesley Chadwick
BACKGROUND: Fissure sealant (FS) and fluoride varnish (FV) have been shown to be effective in preventing dental caries when tested against a no-treatment control. However, the relative clinical effectiveness and cost-effectiveness of these interventions is unknown. OBJECTIVE: To compare the clinical effectiveness and cost-effectiveness of FS and FV in preventing dental caries in first permanent molars (FPMs) in 6- and 7-year-olds and to determine their acceptability...
April 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28611332/gingival-tissue-proliferation-into-the-tooth-following-iatrogenic-miniscrew-insertion-a-newer-underreported-complication
#15
Thavarajah Rooban, Nathamuni Rengarajan Krishnaswamy, Valai Kasim Shakeel Ahmed
Miniscrew implant (MSI) has been reported to be an excellent, supportive orthodontic anchorage tool. The placement of MSI is not free from complication and foremost of which is penetration of MSI into the vital tooth structures. This case report is probably the first to report a newer underreported complication. Interestingly, a small bit of gingival tissue was found deep inside the dentin of the tooth, surviving and proliferating in the MSI-damaged zone. This case report is probably the first to give direct histological evidence in humans that a MSI can cause implantation phenomenon which has the potential to give rise to numerous pathologies including pulpal, periodontal, and cystic transformation...
March 2017: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/28610709/effect-of-dimethyl-sulfoxide-on-dentin-collagen
#16
P Mehtälä, D H Pashley, L Tjäderhane
OBJECTIVES: Infiltration of adhesive on dentin matrix depends on interaction of surface and adhesive. Interaction depends on dentin wettability, which can be enhanced either by increasing dentin surface energy or lowering the surface energy of adhesive. The objective was to examine the effect of dimethyl sulfoxide (DMSO) on demineralized dentin wettability and dentin organic matrix expansion. METHODS: Acid-etched human dentin was used for sessile drop contact angle measurement to test surface wetting on 1-5% DMSO-treated demineralized dentin surface, and linear variable differential transformer (LVDT) to measure expansion/shrinkage of dentinal matrix...
June 10, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28609509/connective-tissue-graft-and-crown-resin-composite-restoration-for-the-treatment-of-gingival-recession-associated-with-noncarious-cervical-lesions-case-series
#17
Camila Augusto Silveira, Ingrid Fernandes Mathias, Felipe Lucas da Silva Neves, Nídia Cristina Castro Dos Santos, Cássia Fernandes Araújo, Maria Aparecida Neves Jardini, Eduardo Bresciani, Mauro Pedrine Santamaria
The purpose of this case series is to describe a restorative and surgical approach to treat the combined defect (CD)-gingival recession associated with noncarious cervical lesions (NCCL)-through connective tissue graft in combination with partial resin composite filling, restoring the crown zone plus 1 mm of the NCCL. A total of 10 patients were included. Bleeding on probing, probing depth, relative gingival recession, clinical attachment level, CD height, and dentin hypersensitivity were measured. The treatment provided statistically significant gain in clinical attachment level and shallow probing depths...
July 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28608628/the-role-of-microrna-143-5p-in-the-differentiation-of-dental-pulp-stem-cells-into-odontoblasts-by-targeting-runx2-via-the-opg-rankl-signaling-pathway
#18
Fu-Liang Zhan, Xin-Yang Liu, Xing-Bo Wang
This study aims to elucidate the mechanisms by which microRNA-143-5p (miR-143-5p) targets runt-related transcription factor 2 (Runx2) in the differentiation of dental pulp stem cells (DPSCs) into odontoblasts, through regulating the osteoprotegerin receptor activator of the nuclear factor-κB ligand (OPG/RANKL) signaling pathway. Following transfection, DPSCs were divided into blank, control, miR-143-5p mimics, miR-143-5p inhibitors, miR-143-5p inhibitors + siRunx2 and siRunx2 groups. Alkaline phosphatase (ALP) activity and mineralized nodules were detected using ALP kit and alizarin red staining...
June 13, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28608463/effect-of-etching-on-bonding-of-a-self-etch-adhesive-to-dentine-affected-by-amelogenesis-imperfecta
#19
Don Jeevanie Epasinghe, Cynthia Kar Yung Yiu
AIM: Dentine affected by amelogenesis imperfecta (AI) is histologically altered due to loss of hypoplastic enamel and becomes hypermineralized. In the present study, we examined the effect of additional acid etching on microtensile bond strength of a self-etch adhesive to AI-affected dentine. METHODS: Flat coronal dentine obtained from extracted AI-affected and non-carious permanent molars were allocated to two groups: (a) Clearfil SE Bond (control); and (b) Clearfil SE Bond and additional etching with 34% phosphoric acid for 15 seconds...
June 13, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28607556/factors-affecting-the-periapical-status-of-root-filled-canals-a-cross-sectional-study-at-the-undergraduate-level
#20
George Moreira Costa, Suelleng Maria Santos Soares, Paula Cristina Pelli Paiva, Flaviana Dornela Verli, Patrícia Furtado Gonçalves, Sangela Maria da Silva Pereira, Rudys Rodolfo De Jesus Tavarez, Janir Alves Soares, Etevaldo Matos Maia Filho
OBJECTIVE: The aim was to evaluate the influence of multiple factors on the periapical status of endodontically treated (ET) teeth. METHODS: The patients were clinically and radiographically reevaluated after root canal therapy. The quality of the root-filled canals, coronal restorations, intraradicular posts, dental caries, and periodontal parameters were associated with the teeth's periapical status. RESULTS: The 122 patients provided 154 ET teeth; 97...
2017: International Journal of Dentistry
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