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https://www.readbyqxmd.com/read/29352204/local-structure-nucleation-sites-and-crystallization-behavior-and-their-effects-on-magnetic-properties-of-fe81si-x-b10p8-xcu1-x%C3%A2-%C3%A2-0-8
#1
C C Cao, Y G Wang, L Zhu, Y Meng, X B Zhai, Y D Dai, J K Chen, F M Pan
In this work, an attempt has been made to reveal critical factors dominating the crystallization and soft magnetic properties of Fe81Si x B10P8-xCu1 (x = 0, 2, 4, 6 and 8) alloys. Both melt spun and annealed alloys are characterized by differential scanning calorimetry, X-ray diffractometry, Mössbauer spectroscopy, transmission electron microscopy, positron annihilation lifetime spectroscopy and magnetometry. The changes in magnetic interaction between Fe atoms and chemical homogeneity can well explain the variation of magnetic properties of Fe81Si x B10P8-xCu1 amorphous alloys...
January 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29352132/design-of-non-equiatomic-medium-entropy-alloys
#2
Yang Zhou, Dong Zhou, Xi Jin, Lu Zhang, Xingyu Du, Bangsheng Li
High-entropy alloys have attracted much attention due to their unique microstructures and excellent properties. Since their invention more than ten years ago, research attention has been mainly focused on the study of multicomponent alloys with equiatomic or near-equiatomic compositions. Here we propose a novel design of non-equiatomic medium-entropy alloys that contain one matrix element and several equiatomic alloying elements. To verify the utility of this new design, a series of Co-free Fex(CrNiAl)100-x (at...
January 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29350397/the-burden-of-non-melanoma-skin-cancers-in-auckland-new-zealand
#3
Ashwini Pondicherry, Richard Martin, Ineke Meredith, Jack Rolfe, Patrick Emanuel, Mark Elwood
BACKGROUND/OBJECTIVES: As the New Zealand Cancer Registry does not require mandatory reporting of non-melanoma skin cancers (NMSC), basal cell carcinomas (BCC) and squamous cell carcinomas (SCC), the clinical burden of these diseases is unknown. METHODS: A retrospective review of all patients with histopathology performed allowed us to estimate invasive BCC and SCC in the Auckland region in 2008 (population 1.44 million). RESULTS: During this period, a total of 21 236 NMSC were diagnosed among 13 996 patients, consisting of 5611 SCC lesions (26%) and 15 525 (74%) BCC...
January 19, 2018: Australasian Journal of Dermatology
https://www.readbyqxmd.com/read/29349770/retrospective-audit-of-patients-referred-for-further-treatment-following-mohs-surgery-for-non-melanoma-skin-cancer
#4
Edmund Wee, Michelle S Goh, Vanessa Estall, Albert Tiong, Angela Webb, Catherine Mitchell, William Murray, Phillip Tran, Christopher J McCormack, Michael Henderson, Emma L Hiscutt
BACKGROUND/OBJECTIVES: To describe the characteristics, subsequent management and outcomes of patients referred for further management following Mohs micrographic surgery (MMS) for basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). METHODS: Retrospective analysis of patients referred to a quaternary cancer centre from 2000 to 2015. RESULTS: In total, 83 lesions in 82 patients were referred for further management; 52 (62%) were SCC and 80 (96%) were located in the head and neck...
January 18, 2018: Australasian Journal of Dermatology
https://www.readbyqxmd.com/read/29348525/cordybislactone-a-stereoisomer-of-the-14-membered-bislactone-clonostachydiol-from-the-hopper-pathogenic-fungus-cordyceps-sp-bcc-49294-revision-of-the-absolute-configuration-of-clonostachydiol
#5
Ken-Ichi Ojima, Arunrat Yangchum, Pattiyaa Laksanacharoen, Kanoksri Tasanathai, Donnaya Thanakitpipattana, Hidetoshi Tokuyama, Masahiko Isaka
Cordybislactone (3), a new stereoisomer of the 14-membered bislactone clonostachydiol, together with its open ring analog (4), was isolated from the hopper pathogenic fungus Cordyceps sp. BCC 49294. The relative and absolute configurations of 3 were determined by chemical derivatizations, including the modified Mosher's method. The stereochemistry of clonostachydiol was determined using the natural compound isolated from Xylaria sp. BCC 4297. The result revealed that the absolute configuration of clonostachydiol, previously determined by synthesis, should be revised to its enantiomer...
January 18, 2018: Journal of Antibiotics
https://www.readbyqxmd.com/read/29348431/a-synthetic-combinatorial-approach-to-disabling-deviant-hedgehog-signaling
#6
C-W Fan, N Yarravarapu, H Shi, O Kulak, J Kim, C Chen, L Lum
Mutations in components of the Hedgehog (HH) signal transduction pathway are found in the majority of basal cell carcinoma (BCC) and medulloblastoma incidents. Cancerous cells with intrinsic or acquired resistance to antagonists targeting the seven transmembrane effector Smoothened (SMO) frequently invoke alternative mechanisms for maintaining deviant activity of the GLI DNA binding proteins. Here we introduce a chemical agent that simultaneously achieves inhibition of SMO and GLI activity by direct targeting of the SMO heptahelical domain and the GLI-modifying enzymes belonging to the histone deacetylase (HDAC) family...
January 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29348199/origins-of-low-symmetry-phases-in-asymmetric-diblock-copolymer-melts
#7
Kyungtae Kim, Akash Arora, Ronald M Lewis, Meijiao Liu, Weihua Li, An-Chang Shi, Kevin D Dorfman, Frank S Bates
Cooling disordered compositionally asymmetric diblock copolymers leads to the formation of nearly spherical particles, each containing hundreds of molecules, which crystallize upon cooling below the order-disorder transition temperature (TODT). Self-consistent field theory (SCFT) reveals that dispersity in the block degrees of polymerization stabilizes various Frank-Kasper phases, including the C14 and C15 Laves phases, which have been accessed experimentally in low-molar-mass poly(isoprene)-b-poly(lactide) (PI-PLA) diblock copolymers using thermal processing strategies...
January 18, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29347305/antiswarming-structure-and-dynamics-of-repulsive-chemically-active-particles
#8
Wen Yan, John F Brady
Chemically active Brownian particles with surface catalytic reactions may repel each other due to diffusiophoretic interactions in the reaction and product concentration fields. The system behavior can be described by a "chemical" coupling parameter Γ_{c} that compares the strength of diffusiophoretic repulsion to Brownian motion, and by a mapping to the classical electrostatic one component plasma (OCP) system. When confined to a constant-volume domain, body-centered cubic (bcc) crystals spontaneously form from random initial configurations when the repulsion is strong enough to overcome Brownian motion...
December 2017: Physical Review. E
https://www.readbyqxmd.com/read/29347271/machine-learning-approach-for-local-classification-of-crystalline-structures-in-multiphase-systems
#9
C Dietz, T Kretz, M H Thoma
Machine learning is one of the most popular fields in computer science and has a vast number of applications. In this work we will propose a method that will use a neural network to locally identify crystal structures in a mixed phase Yukawa system consisting of fcc, hcp, and bcc clusters and disordered particles similar to plasma crystals. We compare our approach to already used methods and show that the quality of identification increases significantly. The technique works very well for highly disturbed lattices and shows a flexible and robust way to classify crystalline structures that can be used by only providing particle positions...
July 2017: Physical Review. E
https://www.readbyqxmd.com/read/29346953/quantum-statistical-effects-in-the-mass-transport-of-interstitial-solutes-in-a-crystalline-solid
#10
C H Woo, Haohua Wen
The impact of quantum statistics on the many-body dynamics of a crystalline solid at finite temperatures containing an interstitial solute atom (ISA) is investigated. The Mori-Zwanzig theory allows the many-body dynamics of the crystal to be formulated and solved analytically within a pseudo-one-particle approach using the Langevin equation with a quantum fluctuation-dissipation relation (FDR) based on the Debye model. At the same time, the many-body dynamics is also directly solved numerically via the molecular dynamics approach with a Langevin heat bath based on the quantum FDR...
September 2017: Physical Review. E
https://www.readbyqxmd.com/read/29346937/uhlenbeck-ford-model-phase-diagram-and-corresponding-states-analysis
#11
Rodolfo Paula Leite, Pedro Antonio Santos-Flórez, Maurice de Koning
Using molecular dynamics simulations and nonequilibrium thermodynamic-integration techniques we compute the Helmholtz free energies of the body-centered-cubic (bcc), face-centered-cubic (fcc), hexagonal close-packed, and fluid phases of the Uhlenbeck-Ford model (UFM) and use the results to construct its phase diagram. The pair interaction associated with the UFM is characterized by an ultrasoft, purely repulsive pair potential that diverges logarithmically at the origin. We find that the bcc and fcc are the only thermodynamically stable crystalline phases in the phase diagram...
September 2017: Physical Review. E
https://www.readbyqxmd.com/read/29346530/bacterioplankton-composition-in-tropical-high-elevation-lakes-of-the-andean-plateau
#12
Pablo Aguilar, Cristina Dorador, Irma Vila, Ruben Sommaruga
High-elevation lakes in the tropics are subject to extreme environmental fluctuations and microbes may harbour a unique genomic repertoire, but their composition and diversity are largely unknown. Here we compared the planktonic bacterial community composition (BCC) and diversity of three tropical lakes located in the high Andean plateau (???4400 m above sea level) during the dry and wet season. Diversity in these lakes was higher in the cool and wet season than in the warm and dry one. OTUs composition was significantly different among lakes and between seasons...
January 16, 2018: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/29346379/a-putative-lateral-flagella-of-the-cystic-fibrosis-pathogen-burkholderia-dolosa-regulates-swimming-motility-and-host-cytokine-production
#13
Damien Roux, Matthew Schaefers, Bradley S Clark, Molly Weatherholt, Diane Renaud, David Scott, John J LiPuma, Gregory Priebe, Craig Gerard, Deborah R Yoder-Himes
Burkholderia dolosa caused an outbreak in the cystic fibrosis clinic at Boston Children's Hospital and was associated with high mortality in these patients. This species is part of a larger complex of opportunistic pathogens known as the Burkholderia cepacia complex (Bcc). Compared to other species in the Bcc, B. dolosa is highly transmissible; thus understanding its virulence mechanisms is important for preventing future outbreaks. The genome of one of the outbreak strains, AU0158, revealed a homolog of the lafA gene encoding a putative lateral flagellin, which, in other non-Bcc species, is used for movement on solid surfaces, attachment to host cells, or movement inside host cells...
2018: PloS One
https://www.readbyqxmd.com/read/29344710/radiation-doses-to-operators-in-hepatobiliary-interventional-procedures
#14
Sarah Degiorgio, Roberta Gerasia, Ferdinanda Liotta, Luigi Maruzzelli, Kelvin Cortis, Roberto Miraglia, Angelo Luca
PURPOSE: The primary aim of this study is to provide a summary of operators' radiation doses during hepatobiliary fluoroscopic guided procedures. In addition, patient dose in these procedures was also documented. MATERIALS AND METHODS: A total of 283 transarterial chemoembolisation (TACE) and 302 biliary procedures, including 52 percutaneous transhepatic cholangiogram (PTC), 36 bilioplasty and 214 biliary catheter changes (BCC) performed over 14 months, were included...
January 17, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29341657/triple-junction-at-the-triple-point-resolved-on-the-individual-particle-level
#15
M Chaudhuri, E Allahyarov, H Löwen, S U Egelhaaf, D A Weitz
At the triple point of a repulsive screened Coulomb system, a fcc crystal, a bcc crystal, and a fluid phase coexist. At their intersection, these three phases form a liquid groove, the triple junction. Using confocal microscopy, we resolve the triple junction on a single-particle level in a model system of charged PMMA colloids in a nonpolar solvent. The groove is found to be extremely deep and the incommensurate solid-solid interface to be very broad. Thermal fluctuations hence appear to dominate the solid-solid interface...
September 22, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29341291/dermoscopy-of-basal-cell-carcinoma
#16
REVIEW
A Wozniak-Rito, I Zalaudek, L Rudnicka
Dermoscopy is widely used in dermatological practice. The method increases the accuracy of basal cell carcinoma (BCC) detection. Pigmented and nonpigmented variants of basal cell carcinoma present different dermoscopic features. Specific dermoscopy criteria have been recognized in different subtypes of BCC. Differentiation of superficial BCC from other subtypes is the most important issue, as it may determine further management decisions.
January 17, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29340714/taxonomical-resolution-and-distribution-of-bacterioplankton-along-the-vertical-gradient-reveals-pronounced-spatiotemporal-patterns-in-contrasted-temperate-freshwater-lakes
#17
J Keshri, A S Pradeep Ram, P A Nana, T Sime-Ngando
We examined the relationship between viruses and co-occurring bacterial communities across spatiotemporal scale in two contrasting freshwater lakes, namely meromictic Lake Pavin and dimictic Lake Aydat (Central France). Next-generation sequencing of 16S rRNA genes suggested distinct patterns in bacterioplankton community composition (BCC) between the lakes over depths and seasons. BCC were generally dominated by members of Actinobacteria, Proteobacteria, and Bacteroidetes covering about 95% of all sequences...
January 16, 2018: Microbial Ecology
https://www.readbyqxmd.com/read/29331385/guidelines-of-care-for-the-management-of-basal-cell-carcinoma
#18
Christian Baum, Jeremy S Bordeaux, Marc Brown, Klaus J Busam, Daniel B Eisen, Vivek Iyengar, Clifford Lober, David J Margolis, Jane Messina, Alexander Miller, Stanley Miller, Eliot Mostow, Christen Mowad, Kishwer Nehal, Kristi Schmitt-Burr, Aleksandar Sekulic, Paul Storrs, Joyce Teng, Siegrid Yu, Conway Huang, Kevin Boyer, Wendy Smith Begolka, Murad Alam, John Y S Kim, Jeffrey H Kozlow, Bharat Mittal, Jeffrey Moyer, Thomas Olencki, Phillip Rodgers
Basal cell carcinoma (BCC) is the most common form of human cancer, with a continually increasing annual incidence in the United States. When diagnosed early, the majority of BCCs are readily treated with office-based therapy, which is highly curative. In these evidence-based guidelines of care, we provide recommendations for the management of patients with BCC, as well as an in-depth review of the best available literature in support of these recommendations. We discuss biopsy techniques for a clinically suspicious lesion and offer recommendations for the histopathologic interpretation of BCC...
January 3, 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29331120/on-the-mechanical-stability-of-the-body-centered-cubic-phase-and-the-emergence-of-a-metastable-ci16-phase-in-classical-hard-sphere-solids
#19
Vadim B Warshavsky, David M Ford, Peter A Monson
The stability of the body-centered cubic (bcc) solid phase of classical hard spheres is of intrinsic interest and is also relevant to the development of perturbation theories for bcc solids of other model systems. Using canonical ensemble Monte Carlo, we simulated systems initialized in a perfect bcc lattice at various densities in the solid region. We observed that the systems rapidly evolved into one of four structures that then persisted for the duration of the simulation. Remarkably, one of these structures was identified as cI16, a cubic crystalline structure with 16 particles in the unit cell, which has recently been observed experimentally in lithium and sodium solids at high pressures...
January 14, 2018: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29331035/noninvasive-optical-spectroscopy-for-identification-of-non-melanoma-skin-cancer-pilot-study
#20
David J Carpenter, Mirabelle B Sajisevi, Nikita Chapurin, Clifford Scott Brown, Tracy Cheng, Gregory M Palmer, Daniel S Stevenson, Caroline L Rao, Russell P Hall, Charles R Woodard
OBJECTIVE: Optical spectroscopy offers a noninvasive alternative to biopsy as a first-line screening tool for suspicious skin lesions. This study sought to define several optical parameters across malignant and benign tissue types. STUDY DESIGN: Prospective pilot trial utilizing the Zenalux IM1 optical spectroscopy device from April 2016 to February 2017. For each skin lesion, provider pre-biopsy probability of malignancy was compared to histolopathologic diagnosis...
January 13, 2018: Lasers in Surgery and Medicine
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