Areez Shafqat, Hassan Elmaleh, Ali Mushtaq, Zaina Firdous, Omer Ashruf, Debduti Mukhopadhyay, Maheen Ahmad, Mahnoor Ahmad, Shahzad Raza, Faiz Anwer
AL amyloidosis is caused by the excessive production of nonfunctional immunoglobulins, leading to the formation of amyloid fibrils that damage vital organs, especially the heart and kidneys. AL amyloidosis presents with non-specific symptoms such as fatigue, weight loss, numbness, pain, and nephrotic syndrome. Consequently, diagnosis is often delayed, and patients typically present with advanced disease at diagnosis. The Pavia renal staging model stratifies patients based on their likelihood of progressing to dialysis...
March 18, 2024: Journal of Clinical Medicine