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https://www.readbyqxmd.com/read/29786707/biocompatible-alkyl-cyanoacrylates-and-their-derivatives-as-bio-adhesives
#1
REVIEW
Jay M Korde, Balasubramanian Kandasubramanian
Cyanoacrylate adhesives and their homologues have elicited interest over the past few decades owing to their applications in the biomedical sector, extending from tissue adhesives to scaffolds to implants to dental material and adhesives, because of their inherent biocompatibility and ability to polymerize solely with moisture, thanks to which they adhere to any substrate containing moisture such as the skin. The ability to tailor formulations of alkyl cyanoacrylate to form derivative compounds to meet application requirements along with their biodegradability in conjunction with their inherent biocompatibility make them highly sought after candidates in the biomedical sector...
May 22, 2018: Biomaterials Science
https://www.readbyqxmd.com/read/29778468/herd-level-associations-between-human-animal-relationship-management-fecal-cortisol-metabolites-and-udder-health-of-organic-dairy-cows
#2
S Ivemeyer, C Simantke, A Ebinghaus, P H Poulsen, J T Sorensen, T Rousing, R Palme, U Knierim
Impact patterns of human-animal relationship (HAR) and herd stress level on udder health were investigated in a cross-sectional study on 30 German and Danish organic dairy herds also taking into account influencing factors regarding housing and management. Cow behavior (avoidance distance, tolerance to tactile interaction, release behavior) was assessed in tests, milkers' behavior recorded during milking, and information about contacts with animals during routine work gathered by interview. Additionally, stockpersons' attitudes were recorded via questionnaires...
May 16, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29777253/translation-inhibition-corrects-aberrant-localization-of-mutant-alanine-glyoxylate-aminotransferase-possible-therapeutic-approach-for-hyperoxaluria
#3
Ruth Belostotsky, Roman Lyakhovetsky, Michael Y Sherman, Fanny Shkedy, Shimrit Tzvi-Behr, Roi Bar, Bernd Hoppe, Björn Reusch, Bodo B Beck, Yaacov Frishberg
Primary hyperoxaluria type 1 is a severe kidney stone disease caused by abnormalities of the peroxisomal alanine-glyoxylate aminotransferase (AGT). The most frequent mutation G170R results in aberrant mitochondrial localization of the active enzyme. To evaluate the population of peroxisome-localized AGT, we developed a quantitative Glow-AGT assay based on the self-assembly split-GFP approach and used it to identify drugs that can correct mislocalization of the mutant protein. In line with previous reports, the Glow-AGT assay showed that mitochondrial transport inhibitors DECA and monensin increased peroxisomal localization of the mutant...
May 18, 2018: Journal of Molecular Medicine: Official Organ of the "Gesellschaft Deutscher Naturforscher und Ärzte"
https://www.readbyqxmd.com/read/29773528/a-digital-app-to-aid-detection-monitoring-and-management-of-dyslexia-in-young-children-dimmand-protocol-for-a-digital-health-and-education-solution
#4
Mariam R Sood, Annet Toornstra, Martin I Sereno, Mark Boland, Daniele Filaretti, Anuj Sood
BACKGROUND: Dyslexia, a specific learning difficulty and a disability as defined in the Equality Act 2010, is a lifelong condition that affects a child from the start of education. Dyslexia is characterized by difficulties in language processing (reading, spelling, and writing) which do not correspond with the child's general intellectual abilities. Although dyslexia cannot be cured, there is a consensus that interventions are more effective and have greater impact the earlier they are administered...
May 17, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29771077/-observation-of-flupentixol-and-melitracen-on-curative-effect-of-sudden-deafness-patients-with-anxiety-and-depression-in-different-stages
#5
T Zhang, G D Yu
Objective: To investigate the efficacy of flupentixol melitracen on different stages of sudden deafness patients with anxiety and depression. Method: Totally one hundred and sixty-three sudden deafness patients with anxiety and depression were randomly divided into two groups: experimental group(81 cases) and control group (82 cases). All patients were given routine treatment for 2 weeks. The experimental group was given oral flupentixol melitracen (1 tablet/day)for a period of 3 months. The hearing, tinnitus effect and vertigo treatment course were observed and compared...
May 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29768265/disease-burden-psychological-well-being-and-attitudes-regarding-the-set-of-emergency-medication-in-adults-with-insect-venom-allergy
#6
Marthe-Lisa Schaarschmidt, Mandy Gutknecht, Lisa Schoeben, Astrid Schmieder
BACKGROUND: Insect venom allergy is common and greatly impairs patients' quality of life. Additionally, low compliance with carrying emergency medication is reported. The aim of our study was to analyze the disease burden, levels of anxiety and depression, and to evaluate attitudes towards the set of emergency medication in affected patients. METHODS: Between April 2016 and January 2017, patients ≥18 years visiting our department because of an insect venom allergy were asked to complete a paper-based questionnaire...
May 16, 2018: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29763597/a-hem-o-lok-induced-tracheoesophageal-fistula-cured-by-temporary-airway-stenting-modified-with-three-dimensional-printing
#7
Yichao Han, Su Yang, Wei Huang, Zhongmin Wang, Hecheng Li
We present the case of a fistula between the trachea and the esophagogastric anastomosis in a 58-year-old male after esophagectomy. A Hem-o-Lok clip used at the time to ligate the azygos vein was discovered by esophagoscopy and bronchoscopy to be eroding into the both structures. A covered self-expandable Y-shaped metallic tracheobronchial stent was customized with a 3D printed airway model and inserted in place, with endoscopic injection of fibrin glue to the anastomotic site. 64 days after implantation, the stent was withdrawn with complete healing of the fistula...
May 12, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29763434/ibuprofen-versus-pivmecillinam-for-uncomplicated-urinary-tract-infection-in-women-a-double-blind-randomized-non-inferiority-trial
#8
Ingvild Vik, Marianne Bollestad, Nils Grude, Anders Bærheim, Eivind Damsgaard, Thomas Neumark, Lars Bjerrum, Gloria Cordoba, Inge Christoffer Olsen, Morten Lindbæk
BACKGROUND: Although uncomplicated urinary tract infections (UTIs) are often self-limiting, most patients will be prescribed antibiotic treatment. We assessed whether treatment with ibuprofen was non-inferior to pivmecillinam in achieving symptomatic resolution by day 4, with a non-inferiority margin of 10%. METHODS AND FINDINGS: This was a randomized, controlled, double-blind non-inferiority trial. We recruited patients from 16 sites in a general practice setting in Norway, Sweden, and Denmark...
May 2018: PLoS Medicine
https://www.readbyqxmd.com/read/29762187/reliability-of-the-osstell-implant-stability-quotient-and-penguin-resonance-frequency-analysis-to-evaluate-implant-stability
#9
Gul Buyukguclu, Zeynep Ozkurt-Kayahan, Ender Kazazoglu
PURPOSE: To evaluate the reliability of the Osstell implant stability quotient (ISQ) and Penguin resonance frequency analysis (RFA) devices in measuring implant stability. MATERIALS AND METHODS: Forty implants were embedded in self-curing acrylic resin, soft-lining material, polyvinyl siloxane impression material, and polycarboxylate cement (n = 10). After the initial setting times were completed, the stability of each implant was measured with Osstell ISQ and Penguin RFA with 3 repeated measurements...
May 10, 2018: Implant Dentistry
https://www.readbyqxmd.com/read/29756132/comparison-between-five-cad-cam-systems-for-fit-of-zirconia-copings
#10
Syed Rashid Habib, Asim Khaled Al Otaibi, Talal Ali Al Anazi, Samer Mosleh Al Anazi
OBJECTIVE: The aim of this in-vitro study was to investigate the marginal and internal fit of zirconia copings fabricated by five CAD/CAM (computer-aided design/computer-assisted manufacture) systems. METHOD AND MATERIALS: A typodont mandibular right first molar was prepared according to ideal parameters for a zirconia crown, scanned digitally, and 100 identical resin dies fabricated by 3D printing. Samples were randomly divided into five groups and sent to CAD/CAM systems for zirconia copings (A, Ceramill-Motion 2, Amann Girrbach; B, Weiland, Ivoclar Vivadent; C, Cerec, Ivoclar Vivadent; D, Prettau Zirconia, Zirkonzahn; E, Cad4dent)...
2018: Quintessence International
https://www.readbyqxmd.com/read/29750050/does-the-internet-promote-the-unregulated-use-of-fecal-microbiota-transplantation-a-potential-public-health-issue
#11
Jonathan Philip Segal, Faisal Abbasi, Cynthia Kanagasundaram, Ailsa Hart
Introduction: The Internet has become an increasingly popular resource for medical information. Fecal microbiota transplantation (FMT) has changed the treatment of Clostridium difficile with cure rates of 81% following one infusion of FMT, further studies have since validated these findings. The Medicines and Health care Products Regulatory Agency has classified FMT as a medicine and hence should be only utilized in strict clinical settings. Methods: We searched Facebook, Twitter, Google, and YouTube using the words "Faecal Microbiota Transplantation" and "FMT"...
2018: Clinical and Experimental Gastroenterology
https://www.readbyqxmd.com/read/29743687/rapid-energy-efficient-manufacturing-of-polymers-and-composites-via-frontal-polymerization
#12
Ian D Robertson, Mostafa Yourdkhani, Polette J Centellas, Jia En Aw, Douglas G Ivanoff, Elyas Goli, Evan M Lloyd, Leon M Dean, Nancy R Sottos, Philippe H Geubelle, Jeffrey S Moore, Scott R White
Thermoset polymers and composite materials are integral to today's aerospace, automotive, marine and energy industries and will be vital to the next generation of lightweight, energy-efficient structures in these enterprises, owing to their excellent specific stiffness and strength, thermal stability and chemical resistance1-5 . The manufacture of high-performance thermoset components requires the monomer to be cured at high temperatures (around 180 °C) for several hours, under a combined external pressure and internal vacuum 6 ...
May 2018: Nature
https://www.readbyqxmd.com/read/29742254/effects-of-three-silane-primers-and-five-adhesive-agents-on-the-bond-strength-of-composite-material-for-a-computer-aided-design-and-manufacturing-system
#13
Ayano Shinohara, Yohsuke Taira, Michino Sakihara, Takashi Sawase
Objective The objective of this study was to evaluate the effects of combinations of silane primers and adhesive agents on the bond strength of a composite block for a computer-aided design and manufacturing system. Material and Methods Three silane primers [Clearfil Ceramic Primer (CP), Super-Bond PZ Primer (PZ), and GC Ceramic Primer II (GP)] were used in conjunction with five adhesive agents [G-Premio Bond (P-Bond), Repair Adhe Adhesive (R-Adhesive), Super-Bond D-Liner Dual (SB-Dual), Super-Bond C&B (SB-Self), and SB-Dual without tributylborane derivative (SB-Light)]...
2018: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/29742232/can-low-fusing-glass-application-affect-the-marginal-misfit-and-bond-strength-of-y-tzp-crowns
#14
Monize Carelli Felipe Antunes, Jean Soares Miranda, Ronaldo Luís Almeida de Carvalho, Rodrigo Furtado de Carvalho, Estevão Tomomitsu Kimpara, Rodrigo Othávio de Assunção E Souza, Fabíola Pessôa Pereira Leite
To evaluate the effect of different surface treatments on the marginal misfit and retentive strength between Y-TZP crowns and an epoxy resin. Forty (40) epoxy resin (G10) abutments (height: 5mm, conicity: 60, finish line: large chamfer) with equal dimensions were milled and included in polyurethane to simulate the periodontal ligament. Next, 40 Y-TZP crowns (thickness: 1mm) were milled (Cerec in Lab) and randomly divided into four groups (n=10) according to the surface treatment: GS(glaze spray), GP(glaze powder/liquid), P(zirconia primer) and RS(tribochemical silica coating)...
2018: Brazilian Oral Research
https://www.readbyqxmd.com/read/29736385/psychological-interventions-influence-patients-attitudes-and-beliefs-about-their-chronic-pain
#15
Audrey Vanhaudenhuyse, Aline Gillet, Nicole Malaise, Irène Salamun, Stéphanie Grosdent, Didier Maquet, Anne-Sophie Nyssen, Marie-Elisabeth Faymonville
Background: Patients' changing attitudes and beliefs about pain are considered as improvements in the treatment of chronic pain. Multidisciplinary approaches to pain allow modifications of coping strategies of patients, from passive to active. Methods: We investigate how two therapeutic treatments impact patients' attitudes and beliefs regarding pain, as measured with the Survey of Pain Attitudes (SOPA). We allocated 415 patients with chronic pain either to psychoeducation combined with physiotherapy, self-hypnosis combined with self-care learning, or to control groups...
April 2018: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29732230/strangulation-of-the-penis-by-a-metallic-ring-prevention-is-better-than-cure
#16
Hamza Ichaoui, Sataa Sallami, Ahmed Samet, Zied Bokal, Hassan Touinsi
Strangulation of the penis is a rare condition that requires emergency management. Several objects, metallic or not, can be placed on the penis to increase sexual performance or for self-erotic intentions especially in psychotic patients with unusual sexual impulses. The problem of removing the foreign body and repairing the damage is a real challenge for the practitioner and a great stress for the patient. We report a case of a 42-year-old schizophrenic patient who presented to the emergency department for a strangulation of the penis secondary to a metal ring placed at the base of the penis 10 days before the consultation without urinary disorder...
2018: Case Reports in Urology
https://www.readbyqxmd.com/read/29728545/antibacterial-effect-and-tensile-bond-strength-of-self-etching-adhesive-resins-with-and-without-methacryloyloxydodecylpyridinium-bromide-an-in-vitro-study
#17
Madhuram Krishnamurthy, V Naveen Kumar, Ashok Leburu, Chakravarthy Dhanavel, Kasiswamy E Selvendran, Nehrudhas Praveen
Aim: The aim of the present study was to compare the antibacterial activity of a self-etching primer containing antibacterial monomer methacryloyloxydodecylpyridinium bromide (MDPB) (Clearfil protect bond) with a conventional self-etching primer without MDPB (Clearfil SE bond) against Streptococcus mutans and the effect of incorporation of MDPB on the tensile bond strength of the experimental self-etching primer (Clearfil protect bond). Materials and methods: The antibacterial activity of the self-etching primers was assessed using agar disk diffusion method and the diameters of the zones of inhibition were measured and ranked...
April 1, 2018: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29722950/-adipose-derived-stem-cells-for-the-treatment-of-penile-erectile-dysfunction-an-update
#18
REVIEW
Yi Wang, Ya-Min Wang, Chen Chen, Yi-Chun Wang, Ning-Hong Song
Adipose-derived stem cells (ADSCs) are pluripotent stem cells isolated from the adipose tissue and have the potential for self-renewal and multi-directional differentiation into neurogenic cells, smooth muscle cells, endothelial cells, and so on. Erectile dysfunction (ED) is a common male sexual dysfunction that has a negative impact on the lives of the patients and their partners. Current treatments of ED include surgery and medication, with oral 5-phosphodiesterase inhibitors as the first-line drugs. However, a small number of the patients are not sensitive to these therapies and cannot be improved or cured pathologically...
June 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29709240/hygroscopic-expansion-of-self-adhesive-resin-cements-and-the-integrity-of-all-ceramic-crowns
#19
Magdalena Kirsten, Ragai Edward Matta, Renan Belli, Ulrich Lohbauer, Manfred Wichmann, Anselm Petschelt, José Zorzin
OBJECTIVE: Low pH neutralization and subsequent remnant hydrophilicity can lead to hygroscopic expansion of self-adhesive resin cements (SARCs) after water storage. The aim of this in vitro study was to investigate the effects of hygroscopic expansion of SARCs, used as luting and partial core build-up material, on integrity and cement gap thickness increase of all-ceramic CAD/CAM crowns. METHODS: Human third molars (n=48) were prepared and anatomical all-ceramic CAD/CAM crowns were manufactured (VITABLOCS Mark II, VITA Zahnfabrik)...
April 27, 2018: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/29698650/yeast-prions-compared-to-functional-prions-and-amyloids
#20
REVIEW
Reed B Wickner, Herman K Edskes, Moonil Son, Evgeny E Bezsonov, Morgan DeWilde, Mathieu Ducatez
Saccharomyces cerevisiae is an occasional host to an array of prions, most based on self-propagating, self-templating amyloid filaments of a normally soluble protein. [URE3] is a prion of Ure2p, a regulator of nitrogen catabolism, while [PSI+] is a prion of Sup35p, a subunit of the translation termination factor Sup35p. In contrast to the functional prions, [Het-s] of Podospora anserina and [BETA] of yeast, the amyloid-based yeast prions are rare in wild strains, arise sporadically, have an array of prion variants for a single prion protein sequence, have a folded in-register parallel β-sheet amyloid architecture, are detrimental to their hosts, arouse a stress response in the host, and are subject to curing by various host anti-prion systems...
April 23, 2018: Journal of Molecular Biology
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