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https://www.readbyqxmd.com/read/28088505/gaps-in-the-public-s-knowledge-about-chronic-pain-representative-sample-of-hispanic-residents-from-five-states
#1
Barbara J Turner, Yuanyuan Liang, Natalia Rodriguez, Melissa A Valerio, Andrea Rochat, Jennifer S Potter, Paula Winkler
: Educating the general public about chronic pain and its care is a national health priority. We evaluated knowledge, attitudes, and beliefs (KAB) of a five-state, population-based sample of Hispanics aged 35-75 without chronic pain, representing over 8.8 million persons. A web-based survey assessed KAB using an adapted version of the Survey of Pain Attitudes-Brief and self-reported knowledge about chronic pain (nothing, a little, a lot). In unweighted analyses of participants (n=346), mean age was 52...
January 11, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28086858/the-influence-of-adding-modified-zirconium-oxide-titanium-dioxide-nano-particles-on-mechanical-properties-of-orthodontic-adhesive-an-in-vitro-study
#2
Nayef H Felemban, Mohamed I Ebrahim
BACKGROUND: The purpose of this in-vitro study was to examine the effect of incorporating different concentrations of Zirconium oxide-Titanium dioxide (ZrO2-TiO2) nanoparticles, which can have antibacterial properties, on the mechanical properties of an orthodontic adhesive. METHODS: ZrO2-TiO2 (Zirconium oxide, HWNANO, Hongwu International Group Ltd, China) -Titanium dioxide, Nanoshell, USA) nanopowder were incorporated into orthodontic adhesive (Transbond XT, 3 M Unitek, Monrovia, USA) with different concentrations (0...
January 13, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28077291/in-vitro-dentin-barrier-cytotoxicity-testing-of-some-dental-restorative-materials
#3
R D Jiang, H Lin, G Zheng, X M Zhang, Q Du, M Yang
OBJECTIVES: To investigate the cytotoxicity of four dental restorative materials in three-dimensional (3D) L929 cell cultures using a dentin barrier test. METHODS: The cytotoxicities of light-cured glass ionomer cement (Vitrebond), total-etching adhesive (GLUMA Bond5), and two self-etching adhesives (GLUMA Self Etch and Single Bond Universal) were evaluated. The permeabilities of human dentin disks with thicknesses of 300, 500, and 1000μm were standardized using a hydraulic device...
January 8, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28064238/myeloid-malignancies-and-the-microenvironment
#4
Claudia Korn, Simón Méndez-Ferrer
Research in the last few years has revealed a sophisticated interaction network between multiple bone marrow (BM) cells that regulate different hematopoietic stem cell (HSC) properties, such as proliferation, differentiation, localization and self-renewal during homeostasis. These mechanisms are essential to keep the physiological HSC numbers in check and interfere with malignant progression. Besides the identification of multiple mutations and chromosomal aberrations driving the progression of myeloid malignancies, alterations in the niche compartment recently gained attention in contributing to disease progression...
November 15, 2016: Blood
https://www.readbyqxmd.com/read/28062651/an-activist-s-argument-that-participant-values-should-guide-risk-benefit-ratio-calculations-in-hiv-cure-research
#5
David Evans
The patient empowerment movement, spurred by AIDS activism in the 1980s, quickly evolved to encompass how study participants are considered and treated in clinical research. Initially, people fearing death of AIDS sought early access to experimental medications that had not undergone rigorous testing in hopes of extending their lives. Thirty years on, scientists are asking a different set of ethical questions about clinical research, this time in the pursuit of either a sterilising cure or long-term remission for HIV...
January 6, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28059624/pre-clinical-development-of-gene-modification-of-hematopoietic-stem-cells-with-chimeric-antigen-receptors-for-cancer-immunotherapy
#6
Sarah M Larson, Laurel C Truscott, Tzu-Ting Chiou, Amie Patel, Roy Kao, Andy Tu, Tulika Tyagi, Xiang Lu, David Elashoff, Satiro N De Oliveira
Patients with refractory or recurrent B-lineage hematologic malignancies have less than 50% of chance of cure despite intensive therapy and innovative approaches are needed. We hypothesize that gene modification of hematopoietic stem cells (HSC) with an anti-CD19 chimeric antigen receptor (CAR) will produce a multi-lineage, persistent immunotherapy against B-lineage malignancies that can be controlled by the HSVsr39TK suicide gene. High-titer third-generation self-inactivating lentiviral constructs were developed to deliver a second-generation CD19-specific CAR and the herpes simplex virus thymidine kinase HSVsr39TK to provide a suicide gene to allow ablation of gene-modified cells if necessary...
January 6, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28052216/pattern-of-hydroxyapatite-crystal-growth-on-bleached-enamel-following-the-application-of-two-antioxidants-an-atomic-force-microscope-study
#7
Chitra P Bhusari, Divya S Sharma
OBJECTIVES: This study observed the topographical pattern of hydroxyapatite deposition and growth (D&G) on bleached enamel following application of two antioxidants (sodium ascorbate and catalase) using atomic force microscope. STUDY DESIGN: Twenty enamel specimens (4×3×2mm), prepared from extracted impacted third molars, were mounted in self-cure acrylic and randomly grouped as: Group I-untreated; Group II- 35%H2O2; Group III- 35%H2O2 + artificial saliva; Group IV- 35%H2O2 + catalase+ artificial saliva; Group V- 35%H2O2 + sodium ascorbate+ artificial saliva...
2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28050982/effect-of-tannic-acid-on-bond-strength-of-etch-and-rinse-and-self-etch-adhesive-systems-in-dentin-of-primary-teeth
#8
Masoumeh Ebrahimi, Alireza Sarraf Shirazi, Faraneh Abdolhoseinpour, Mojtaba Abdollahi
INTRODUCTION: One of the possible mechanisms for the gradual destruction of bond strength in dentin-resin interface, could be due to the demineralized unstable collagen matrix. Use of protease inhibitors, such as tannic acid (TA) could prevent destruction of collagen fibers. The aim of this study was to compare the TA effect on bond strength of etch and rinse and self-etch adhesive systems in the dentin of primary teeth. MATERIALS AND METHODS: This in vitro study was done on 40 extracted primary molar teeth...
January 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28042259/comparison-of-compressive-strength-among-three-different-intracanal-post-materials-in-primary-anterior-teeth-an-in-vitro-study
#9
Nilavu Nilavarasan, R Hemalatha, R Vijayakumar, V S Hariharan
OBJECTIVE: The objective of our study was to compare the fracture resistance and the mode of failure among three different post materials in primary anterior teeth. MATERIALS AND METHODS: A total of sixty extracted primary anterior teeth were selected for the study. The samples were divided into three groups of twenty teeth each: Group I (Ribbond), Group II (Omega loop), and Group III (Glass fiber post). Pulp therapy was followed by intracanal post and crown buildup...
October 2016: European Journal of Dentistry
https://www.readbyqxmd.com/read/28032892/facing-the-dilemma-of-patient-centred-psoriasis-care-a-qualitative-study-identifying-patient-needs-in-dermatological-outpatient-clinics
#10
L R Khoury, L Skov, T Møller
BACKGROUND: Caregivers must be aware of patients' current needs by providing care responsive to the patients' values and preferences and by identifying what approach improves and encourages patients to participate in their treatment and disease management. Patients with psoriasis healthcare needs perhaps change as medical knowledge improves, new drugs emerge and the healthcare system improves its efficiency due to constant structural development. OBJECTIVES: To explore the unmet needs and health perceptions of people with psoriasis, regarding interaction with clinicians and the structure inherent to consultations in a hospital outpatient dermatological clinic...
December 29, 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/28029082/probiotics-in-curing-allergic-and-inflammatory-conditions-research-progress-and-futuristic-vision
#11
Kuldeep Dhama, Shyma K Latheef, Ashok Kumar Munjal, Rekha Khandia, Hari Abdul Samad, Hafiz M N Iqbal, Sunil K Joshi
BACKGROUND: Probiotics constitute the viable and beneficial microbes, which offer a dietary means to sustain the balance of gastro-intestinal (GI) microflora. Owing to their multiple health benefits, these have recently gained wide attention among researchers for exploring their potential in safeguarding the health of humans and animals. Probiotics could also modulate host-immune responses, thereby help in counteracting the immunological dysfunctions. Probiotics can inhibit the systemic invasion of pathogens entering through the GI mucosa/ oral cavity and have been found to possess effective prophylactic and therapeutic utilities against various infectious pathogens as well as non-infectious diseases and disorders...
December 26, 2016: Recent Patents on Inflammation & Allergy Drug Discovery
https://www.readbyqxmd.com/read/28028417/a-twofold-comparison-between-dual-cure-resin-modified-cement-and-glass-ionomer-cement-for-orthodontic-band-cementation
#12
Hanaa El Attar, Omnia Elhiny, Ghada Salem, Ahmed Abdelrahman, Mazen Attia
AIM: To test the solubility of dual cure resin modified resin cement in a food simulating solution and the shear bond strength compared to conventional Glass ionomer cement. MATERIALS AND METHOD: The materials tested were self-adhesive dual cure resin modified cement and Glass Ionomer (GIC). Twenty Teflon moulds were divided into two groups of tens. The first group was injected and packed with the modified resin cement, the second group was packed with GIC. To test the solubility, each mould was weighed before and after being placed in an analytical reagent for 30 days...
December 15, 2016: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28027422/care-related-predictors-for-negative-intrusive-thoughts-after-prostate-cancer-diagnosis-data-from-the-prospective-lappro-trial
#13
Thordis Thorsteinsdottir, Heiddis Valdimarsdottir, Arna Hauksdottir, Johan Stranne, Ulrica Wilderäng, Eva Haglind, Gunnar Steineck
OBJECTIVE: Negative intrusive thoughts about one's prostate cancer have been associated with depressive mood and impaired quality of life among prostate cancer patients. However, little is known about possible predictors for negative intrusive thoughts among this group. We aimed to identify health- and care-related predictors for such thoughts among a population of men newly diagnosed with prostate cancer and undergoing radical prostatectomy. METHODS: In the LAPPRO-trial, 3154 men (80%) answered study-specific questionnaires at admission and three months after surgery...
December 27, 2016: Psycho-oncology
https://www.readbyqxmd.com/read/28026084/a-cocatalytic-effect-between-meldrum-s-acid-and-benzoxazine-compounds-in-preparation-of-high-performance-thermosetting-resins
#14
Yi Chen, Liang-Kai Lin, Shu-Jen Chiang, Ying-Ling Liu
In this work, a cocatalytic effect between Meldrum's acid (MA) and benzoxazine (Bz) compounds has been explored to build up a self-promoting curing system. Consequently, the MA/Bz reactive blend exhibits a relatively low reaction temperature compared to the required temperatures for the cross-linking reactions of the pure MA and Bz components. This feature is attractive for energy-saving processing issues. Moreover, the thermosetting resins based on the MA/Bz reactive blends have been prepared. The MA component can generate additional free volume in the resulting resins, so as to trap air in the resin matrix and consequently to bring low dielectric constants to the resins...
December 27, 2016: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/28004437/desolvation-induced-origami-of-photocurable-polymers-by-digit-light-processing
#15
Zeang Zhao, Jiangtao Wu, Xiaoming Mu, Haosen Chen, H Jerry Qi, Daining Fang
Self-folding origami is of great interest in current research on functional materials and structures, but there is still a challenge to develop a simple method to create freestanding, reversible, and complex origami structures. This communication provides a feasible solution to this challenge by developing a method based on the digit light processing technique and desolvation-induced self-folding. In this new method, flat polymer sheets can be cured by a light field from a commercial projector with varying intensity, and the self-folding process is triggered by desolvation in water...
December 22, 2016: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/28002695/clinical-effectiveness-of-different-polishing-systems-and-self-etch-adhesives-in-class-v-composite-resin-restorations-two-year-randomized-controlled-clinical-trial
#16
J-H Jang, H-Y Kim, S-M Shin, C-O Lee, D S Kim, K-K Choi, S-Y Kim
The aim of this randomized controlled clinical trial was to compare the clinical effectiveness of different polishing systems and self-etch adhesives in class V composite resin restorations. A total of 164 noncarious cervical lesions (NCCLs) from 35 patients were randomly allocated to one of four experimental groups, each of which used a combination of polishing systems and adhesives. The two polishing systems used were Sof-Lex XT (Sof), a multistep abrasive disc, and Enhance/Pogo (EP), a simplified abrasive-impregnated rubber instrument...
January 2017: Operative Dentistry
https://www.readbyqxmd.com/read/27994319/comparative-evaluation-of-microhardness-of-dentin-treated-with-4-titanium-tetrafluoride-and-1-23-acidic-phosphate-fluoride-gel-before-and-after-exposure-to-acidic-ph-an-ex-vivo-study
#17
Vivek Kandanuru, Koppolu Madhusudhana, Vamsi Krishna Ramachandruni, Harish Madhav Vitta, Lenin Babu
AIM: The aim of this study was to comparatively evaluate the effect of 4% titanium tetrafluoride (TiF4) and 1.23% acidic phosphate fluoride (APF) gel on the microhardness of human coronal dentin. MATERIALS AND METHODS: Thirty noncarious extracted premolars were collected and sectioned buccolingually with the help of diamond disk. Exposing the sectioned surface, teeth were embedded in self-cure acrylic. Exposed coronal dentin was polished with abrasive papers starting with 220-5000 grit...
November 2016: Journal of Conservative Dentistry: JCD
https://www.readbyqxmd.com/read/27984272/association-of-sociodemographic-factors-with-spirituality-and-hope-in-patients-with-diabetic-foot-ulcers
#18
Geraldo Magela Salomé, Sergio Aguinaldo de Almeida, Bruno Mendes, Maiume Roana Ferreira de Carvalho, José Carlos Bueno, Marcelo Renato Massahud, Lydia Masako Ferreira
OBJECTIVE: To evaluate levels of spirituality and hope in patients with diabetic foot ulcers (DFUs) according to sociodemographic factors. DESIGN: This was a primary, prospective, descriptive, analytical, and clinical study. Questionnaires assessing sociodemographic and clinical characteristics of the patients, the Spirituality Self-rating Scale (SSRS), and the Herth Hope Index (HHI) were administered to all participants. SETTING: University-affiliated skilled nursing center and outpatient wound care clinic in Pouso Alegre, Brazil...
January 2017: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/27983936/silencing-of-btbd7-inhibited-epithelial-mesenchymal-transition-and-6-chemoresistance-in-cd133-lung-carcinoma-a549-cells
#19
Li-Zhou Fang, Jian-Qing Zhang, Ling Liu, Wei-Ping Fu, Jing-Kui Shu, Jia-Gang Feng, Xiao Liang
<p>Cancer stem cell (CSC) are responsible for the tumorigenesis and recurrence, so targeting CSCs is a potentialeffective method to cure cancers. BTB/POZ domain-containing protein 7 (Btbd7) has been found in various cancers, including lung cancer and liver cancer, but the role of Btbd7 in non-small cell lung cancer (NSCLC) CSC self-renewal and chemoresistance were still unknown.</p><p>Therefore, in this study, we first found that the radio of tumor sphere formation and stem cell transcription factors in CD133+ cells were dramatically enhanced than parental cells, which indicated successfully sorting the CD133+ cells from A549...
October 26, 2016: Oncology Research
https://www.readbyqxmd.com/read/27982188/tensile-strength-of-resin-cements-used-with-base-metals-in-a-simulating-passive-cementation-technique-for-implant-supported-prostheses
#20
Hilmo Barreto Leite Falcão, Ricardo Faria Ribeiro, Raphael Freitas de Souza, Ana Paula Macedo, Rossana Pereira de Almeida
The aim of this study was to analyze the tensile strength of two different resin cements used in passive cementation technique for implant-supported prosthesis. Ninety-six plastic cylinders were waxed in standardized forms, cast in commercially pure titanium, nickel-chromium and nickel-chromium-titanium alloys. Specimens were cemented on titanium cylinders using self-adhesive resin cement or conventional dual-cured resin cement. Specimens were divided in 12 groups (n=8) in accordance to metal, cement and ageing process...
October 2016: Brazilian Dental Journal
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