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https://www.readbyqxmd.com/read/28743900/long-term-hepatitis-b-infection-in-a-scalable-hepatic-co-culture-system
#1
Benjamin Y Winer, Tiffany S Huang, Eitan Pludwinski, Brigitte Heller, Felix Wojcik, Gabriel E Lipkowitz, Amit Parekh, Cheul Cho, Anil Shrirao, Tom W Muir, Eric Novik, Alexander Ploss
Hepatitis B virus causes chronic infections in 250 million people worldwide. Chronic hepatitis B virus carriers are at risk of developing fibrosis, cirrhosis, and hepatocellular carcinoma. A prophylactic vaccine exists and currently available antivirals can suppress but rarely cure chronic infections. The study of hepatitis B virus and development of curative antivirals are hampered by a scarcity of models that mimic infection in a physiologically relevant, cellular context. Here, we show that cell-culture and patient-derived hepatitis B virus can establish persistent infection for over 30 days in a self-assembling, primary hepatocyte co-culture system...
July 25, 2017: Nature Communications
https://www.readbyqxmd.com/read/28741292/effect-of-mdp-based-silane-and-different-surface-conditioner-methods-on-bonding-of-resin-cements-to-zirconium-framework
#2
Hatice Özdemir, Nuran Yanikoğlu, Nurdan Sağsöz
PURPOSE: To determine the shear bond strength (SBS) between zirconium framework and resin cements after different surface conditioner methods and after application of 10-methacryloyloxydecyl dihydrogen phosphate (MDP) based silane and a bonding agent mix. MATERIALS AND METHODS: 128 disc-shaped zirconium-oxide specimens were prepared. Specimens were placed in autopolymerizing acrylic resin. The bonding surface of specimens was smoothed consecutively with 600-, 800-, and 1200-grit silicon carbide papers under water cooling...
July 24, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/28736604/comparison-between-three-glass-fiber-post-cementation-techniques
#3
Guido Migliau, Luca Piccoli, Stefano Di Carlo, Giorgio Pompa, Laith Konstantinos Besharat, Marco Dolci
OBJECTIVE: The aim of this experimental study was to compare the traditional cement systems with those of the latest generation, to assess if indeed these could represent of viable substitutes in the cementation of indirect restorations, and in the specific case of endodontic posts. METHODS: The assessment of the validity of the cementing methods was performed according to the test of the push-out, conducted on sections obtained from the roots of treated teeth. The samples were divided into three groups...
January 2017: Annali di Stomatologia
https://www.readbyqxmd.com/read/28735788/effect-of-mineral-trioxide-aggregate-apical-plug-thickness-on-fracture-resistance-of-immature-teeth
#4
Ersan Çiçek, Neslihan Yılmaz, M Murat Koçak, Baran Can Sağlam, Sibel Koçak, Burcu Bilgin
INTRODUCTION: The aim of this study was to compare the fracture resistance of simulated immature teeth after using different thicknesses of mineral trioxide aggregate (MTA) apical plugs. METHODS: Fifty-two human maxillary anterior teeth were used. Five teeth were the positive control group; they were prepared using Peeso reamers to simulate immature teeth without any access cavity preparation. Access cavities of the 47 teeth were prepared, and the canals were instrumented with Peeso reamers...
July 20, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28729803/anterosuperior-rehabilitation-with-metal-free-fixed-prosthesis-based-on-zirconia
#5
Sthelen Nayara Cenci, Igor Alessandro Gontarsky, Marcella Goetz Moro, Lidia Olga Bach Pinheiro, Adriana Postiglione Bührer Samra
The loss of upper front dental elements causes functional and psychosocial problems to the affected individuals. In this case report, the treatment planning considered hard and soft tissue loss for a complex fixed partial denture (FPD) rehabilitation. The six-element, all-ceramic FPD was manufactured using a computer-aided design/computer-aided manufacturing system with zirconia framework, veneered with leucite-reinforced ceramic. Ceramic artificial gum was also produced to guarantee tooth-facial proportions as well as lip support, promoting both esthetics and phonetics...
April 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/28729794/assessment-of-resin-dentin-interfacial-morphology-of-two-ethanol-based-universal-adhesives-a-scanning-electron-microscopy-study
#6
Mohamed Moustafa Awad
OBJECTIVE: The objective of this study was to assess the resin-dentin interfacial morphology created by two universal adhesives using scanning electron microscopy (SEM). MATERIALS AND METHODS: The occlusal surfaces of ten (n = 5) molars were reduced to expose a flat surface of dentin. Two universal adhesives, Scotchbond Universal Adhesive and Tetric N-Bond Universal, were independently applied to air-dried dentin. Light-cured resin-based composite restorative materials were used to incrementally build a composite "buildup...
April 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/28729789/in-vitro-evaluation-of-microleakage-under-orthodontic-brackets-bonded-with-different-adhesive-systems
#7
Ramin Atash, Ali Fneiche, Sibel Cetik, Babak Bahrami, Alain Balon-Perin, Maria Orellana, Régine Glineur
OBJECTIVE: Adhesives systems have a drawback when utilized for bonding orthodontic brackets: they shrink during photopolymerization creating microleakage. The aim of this study was to assess the stability of different orthodontic adhesives around brackets and enamel. MATERIALS AND METHODS: Sixty noncarious mandibular premolars extracted for orthodontic reasons were randomly divided into six groups of adhesives used for bonding brackets to dental enamel: NeoBond(®) Light Cure Adhesive Kit, Transbond™ Plus Self-Etching, Victory V-Slot APC PLUS(®) + Transbond™ MIP, Rely-A-Bond(®) Kit, Light Cure Orthodontic Adhesive Kit (OptiBond(®)), and Transbond™ MIP...
April 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/28723368/definition-of-success-after-surgery-for-female-stress-incontinence-or-voiding-dysfunction-an-attempt-at-standardization
#8
REVIEW
Maude E Carmel, Donna Y Deng, Tamsin J Greenwell, Philippe E Zimmern
CONTEXT: There is currently no standardized definition of success for surgery for stress urinary incontinence (SUI) and voiding dysfunction (VD) in women. OBJECTIVE: To review the use of outcome measures (OMs) and definitions of success in the literature on SUI and VD surgery in women in an attempt to provide recommendations for future publications. EVIDENCE ACQUISITION: A PubMed search of all English language full-text articles on SUI and VD surgery in women published between 2010 and 2015 was performed...
August 2016: European Urology Focus
https://www.readbyqxmd.com/read/28722001/enamel-color-changes-following-orthodontic-treatment
#9
REVIEW
Akshaya Pandian, Sukanya Ranganathan, Sridevi Padmanabhan
OBJECTIVE: To evaluate and compare the effect of various orthodontic bonding systems and clean up procedures on quantitative enamel colour change. MATERIALS AND METHODS: A literature search was done to identify the studies that assessed the quantitative enamel colour change associated with the various bonding systems and cleanup procedures. Electronic database (Pub Med, Cochrane and Google Scholar) were searched. First stage screening was performed and the abstracts were selected according to the initial selection criteria...
May 2017: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/28717520/modeling-chronic-dacryocystitis-in-rabbits-by-nasolacrimal-duct-obstruction-with-self-curing-resin
#10
Kai Hou, Tao Ai, Rong Liu, Nan Xiang, Jing Jin, Weikun Hu, Ban Luo
We established a chronic dacryocystitis model by injecting of 0.05, 0.1, and 0.15 ml self-curing resin via the lacrimal punctum in rabbits. Animals were randomized into four groups (n = 11 animals/group). The control group received 0.15 ml normal saline. Within three months postinjection, epiphora and eye discharge were observed. At the 90th day postlacrimal passage irrigation, CT dacryocystography was performed to find changes in the lacrimal image, and hematoxylin and eosin staining was made to identify pathological changes of the lacrimal sac...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28713120/sealing-ability-of-esthetic-post-and-core-systems
#11
Thamer Almohareb
AIM: To review the literature on the sealing ability of esthetic post systems with different cementation techniques. BACKGROUND: An important factor for successful root canal treatment is the development of a coronal seal to the treated root canal system. Review result: The current literature describes promising results using fiber posts with a dual-cure, self-etch resin cement system. However, none of the published results describe a post system or cementation technique that achieved a homogeneous and tight coronal seal...
July 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28708376/self-healing-nano-textured-vascular-like-materials-mode-i-crack-propagation
#12
Minwook Lee, Soumyadip Sett, Seongpil An, Sam Sukgoo Yoon, Alexander L Yarin
Here we investigate crack propagation initiated from an initial notch in a self-healing material. The crack propagation in the core-shell nanofiber mats formed by co-electrospinning and the composites reinforced by them is in focus. All samples are observed from the crack initiation until complete failure. Due to the short-time experiments done on purpose, the resin and cure released from the cores of the core-shell nanofibers could not achieve a complete curing and stop crack growth, especially given the fact that no heating was used...
July 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28707966/targeted-molecular-ablation-of-cancer-stem-cells-for-curing-gastrointestinal-cancers
#13
Yong Seok Kim, Ho Jae Lee, Jong-Min Park, Young-Min Han, Napapan Kangwan, Ji Young Oh, Dong Yoon Lee, Ki Baik Hahm
Abundance of the ATPase-binding cassette (ABC) transporters and deranged self-renewal pathways characterize the presence of cancer stem cells (CSCs) in gastrointestinal cancers (GI cancers), which play crucial roles in tumorigenesis, chemotherapy resistance, tumor recurrence, and cancer metastasis. Therefore, in order to ensure high cure rates, chemoquiescence, CSCs should be ablated. Recent advances in either understanding CSCs or biomarker identification enable scientists to develop techniques for ablating CSCs and clinicians to provide cancer cure, especially in GI cancers characterized by inflammation-driven carcinogenesis...
July 14, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28703320/5-aminolevulinic-acid-patch-pdt-in-the-treatment-of-actinic-cheilitis
#14
Sonja Radakovic, Adrian Tanew
BACKGROUND: Actinic cheilitis (AC) is a common disease caused by chronic ultraviolet exposure. OBJECTIVE: Alacare is a self-adhesive, skin coloured 5-aminolaevulinic acid (ALA) patch that has been developed for the treatment of mild to moderate actinic keratosis (AK). Considering the good results in the treatment of AK, the standardized delivery of ALA and the simple application Alacare patch PDT appears as an interesting treatment option for AC. METHODS: We retrospectively assessed the efficacy, tolerability and cosmetic outcome of Alacare patch PDT in eleven patients with AC...
July 13, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28702394/osteoid-osteoma-radiofrequency-ablation-treatment-guided-by-computed-tomography-a-case-series
#15
Rosana Raquel Endo, Natalia Fabris Gama, Suely Akiko Nakagawa, Chiang Jeng Tyng, Wu Tu Chung, Fábio Fernando Eloi Pinto
The osteoid osteoma is a benign primary bone tumor that affects mainly males in the second and third decades of life. Radiographic findings show a radiolucent nidus surrounded by reactive sclerotic bone, particularly in the long bones of the lower extremity. Clinically, it presents persistent pain, which is worse at night and improves with salicylates. It can be a self-limiting injury, with an average duration of three years, but because of pain intensity and intolerance to prolonged use of nonsteroidal anti-inflammatories, surgical treatment is an option...
May 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28701043/in-situ-x-ray-tomography-study-of-cement-exposed-to-co2-saturated-brine
#16
Elvia Anabela Chavez Panduro, Malin Torsæter, Kamila Gawel, Ruben Bjørge, Alain Gibaud, Yi Yang, Stefan Bruns, Yi Zheng, Henning Osholm Sørensen, Dag W Breiby
For successful CO2 storage in underground reservoirs, the potential problem of CO2 leakage needs to be addressed. A profoundly improved understanding of the behavior of fractured cement under realistic subsurface conditions including elevated temperature, high pressure and the presence of CO2 saturated brine is required. Here, we report in-situ X-ray micro computed tomography (µ-CT) studies visualizing the micro-structural changes upon exposure of cured Portland cement with a leak path to CO2 saturated brine at high pressure...
July 12, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28692844/comparative-bonding-ability-to-dentin-of-a-universal-adhesive-system-and-monomer-conversion-as-functions-of-extended-light-curing-times-and-storage
#17
Paula Costa Pinheiro Sampaio, Paula de Castro Kruly, Clara Cabral Ribeiro, Leandro Augusto Hilgert, Patrícia Nóbrega Rodrigues Pereira, Polliana Mendes Candia Scaffa, Vinicius Di Hipólito, Paulo Henrique Perlatti D'Alpino, Fernanda Cristina Pimentel Garcia
OBJECTIVES: The purpose of this in vitro study was to evaluate the bonding ability and monomer conversion of a universal adhesive system applied to dentin as functions of different curing times and storage. The results were compared among a variety of commercial adhesives. MATERIALS AND METHODS: Flat superficial dentin surfaces were exposed on human molars and assigned into one of the following adhesives (n = 15): total-etch Adper Single Bond 2 (SB) and Optibond Solo Plus (OS), self-etch Optibond All in One (OA) and Clearfil SE Bond (CSE), and Scotchbond Universal Adhesive in self-etch mode (SU)...
June 27, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28691454/temperature-changes-of-one-piece-implants-during-the-setting-of-acrylic-resin-temporary-crown-the-effect-of-implant-diameter-an-in-vitro-study
#18
O Cohen, D Lauritano, O Moses, Z Ormianer, H Tal, R Kolerman, F Carinci, S Matalon
The purpose of this work is to evaluate changes in temperature of one-piece titanium implant surface during the setting of acrylic resin temporary crowns and to correlate thermal changes to implant diameter. Thirty-three one-piece implants (ARRP, Alpha-Biotec) were divided into 3 groups according to diameter size (G1=3 mm, G2=3.3 mm, G3=3.6 mm). Implants were mounted on an acrylic glass apparatus. Thermocouples were positioned at the most coronal thread. Lower incisor temporary polycarbonate crowns were filled with 80 μL of self-curing acrylic resin and positioned immediately on the implant abutment...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28691092/instant-tough-bonding-of-hydrogels-for-soft-machines-and-electronics
#19
Daniela Wirthl, Robert Pichler, Michael Drack, Gerald Kettlguber, Richard Moser, Robert Gerstmayr, Florian Hartmann, Elke Bradt, Rainer Kaltseis, Christian M Siket, Stefan E Schausberger, Sabine Hild, Siegfried Bauer, Martin Kaltenbrunner
Introducing methods for instant tough bonding between hydrogels and antagonistic materials-from soft to hard-allows us to demonstrate elastic yet tough biomimetic devices and machines with a high level of complexity. Tough hydrogels strongly attach, within seconds, to plastics, elastomers, leather, bone, and metals, reaching unprecedented interfacial toughness exceeding 2000 J/m(2). Healing of severed ionic hydrogel conductors becomes feasible and restores function instantly. Soft, transparent multilayered hybrids of elastomers and ionic hydrogels endure biaxial strain with more than 2000% increase in area, facilitating soft transducers, generators, and adaptive lenses...
June 2017: Science Advances
https://www.readbyqxmd.com/read/28690641/prostate-cancer-stem-cell-markers-drive-progression-therapeutic-resistance-and-bone-metastasis
#20
REVIEW
Koran S Harris, Bethany A Kerr
Metastatic or recurrent tumors are the primary cause of cancer-related death. For prostate cancer, patients diagnosed with local disease have a 99% 5-year survival rate; however, this 5-year survival rate drops to 28% in patients with metastatic disease. This dramatic decline in survival has driven interest in discovering new markers able to identify tumors likely to recur and in developing new methods to prevent metastases from occurring. Biomarker discovery for aggressive tumor cells includes attempts to identify cancer stem cells (CSCs)...
2017: Stem Cells International
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