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https://www.readbyqxmd.com/read/28318582/purulent-vaginal-discharge-in-grazing-dairy-cows-risk-factors-reproductive-performance-and-prostaglandin-f2%C3%AE-treatment
#1
M J Giuliodori, M Magnasco, R P Magnasco, I M Lacau-Mengido, R L de la Sota
The objectives of this study were to assess the association of a 4-point scale of vaginal discharge score (VDS) with time to pregnancy to define criteria for a practical case of purulent vaginal discharge (PVD) in dairy cows, to test the risk factors for PVD, and, finally, the effect of a dose of PGF2α on cure and reproductive performance. In experiment 1, grazing Holstein cows (n = 2,414) had their vaginal discharge scored at ∼32 d in milk (DIM) on a 4-point scale, the effect of VDS on the hazard of pregnancy by 300 DIM was then assessed to derive a case definition of PVD...
March 16, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28318156/-comparative-evaluation-of-the-marginal-accuracy-of-single-crowns-fabricated-computer-using-aided-design-computer-aided-manufacturing-methods-self-curing-resin-and-luxatemp
#2
Yuan Jianming, Tang Ying, Pan Feng, Xu Weixing
OBJECTIVE: This study aims to compare the marginal accuracy of single crowns fabricated using self-curing resin, Luxatemp, and computer aided design/computer aided manufacturing (CAD/CAM) methods in clinical application. METHODS: A total of 30 working dies, which were obtained from 30 clinical teeth prepared with full crown as standard, were created and made into 30 self-curing resin, Luxatemp, and CAD/CAM single crowns. The restorations were seated on the working dies, and stereomicroscope was used to observe and measure the thickness of reference points...
December 1, 2016: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28306203/highly-stretchable-superhydrophobic-composite-coating-based-on-self-adaptive-deformation-of-hierarchical-structures
#3
Xin Hu, Changyu Tang, Zhoukun He, Hong Shao, Keqin Xu, Jun Mei, Woon-Ming Lau
With the rapid development of stretchable electronics, functional textiles, and flexible sensors, water-proof protection materials are required to be built on various highly flexible substrates. However, maintaining the antiwetting of superhydrophobic surface under stretching is still a big challenge since the hierarchical structures at hybridized micro-nanoscales are easily damaged following large deformation of the substrates. This study reports a highly stretchable and mechanically stable superhydrophobic surface prepared by a facile spray coating of carbon black/polybutadiene elastomeric composite on a rubber substrate followed by thermal curing...
March 17, 2017: Small
https://www.readbyqxmd.com/read/28302961/getting-to-the-heart-of-the-matter-in-cancer-novel-approaches-to-targeting-cancer-stem-cells
#4
Hugh Colvin, Masaki Mori
Cancer is one of the leading causes of deaths worldwide. While cancers may initially show good response to chemotherapy or radiotherapy, it is not uncommon for them to recur at a later date. This phenomenon may be explained by the existence of a small population of cancer stem cells, which are inherently resistant to anti-cancer treatment as well as being capable of self-renewal. Therefore, while most of the tumour bulk consisting of cells that are not cancer stem cells respond to treatment, the cancer stem cells remain, leading to disease recurrence...
2017: Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
https://www.readbyqxmd.com/read/28298991/fracture-resistance-of-endodontically-treated-teeth-with-different-direct-corono-radicular-restoration-methods
#5
Horieh Moosavi, Safora Afshari, Fatemeh Manari
BACKGROUND: Endodontically treated teeth are widely considered to be more susceptible to fracture than vital teeth. Obturation procedures and post placement have been a main cause of vertical root fracture. MATERIAL AND METHODS: Forty-eight human premolars with standardized weakened roots were endodontically treated and allocated to four experimental groups (n=12). After root canal treatment, in group 1, fiber posts #1 were cemented in root canals using Estelite Core Quick, and the crowns were restored with resin composite...
March 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28298987/effect-of-different-concentrations-of-specific-inhibitor-of-matrix-metalloproteinases-on-the-shear-bond-strength-of-self-adhesive-resin-cements-to-dentin
#6
Mohammad-Esmaeel Ebrahimi-Chaharom, Mehdi Abed-Kahnamoui, Mahmoud Bahari, Hamed Hamishehkar, Mahya Gharouni
BACKGROUND: Considering the probability of chemical and enzymatic reactions between matrix metalloproteinases (MMPs) in the dentin structure and their specific inhibitors, the aim of the present study was to evaluate the effect of different concentrations of specific inhibitor of MMPs (galardin) on the shear bond strength of self-adhesive resin cements to dentin. MATERIAL AND METHODS: Forty-eight sound human premolars were mounted in self-cured acrylic resin after removal of the enamel on the buccal and lingual surfaces...
March 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28291956/physical-activity-motivation-and-benefits-in-people-with-multiple-sclerosis
#7
Kimberly S Fasczewski, Diane L Gill, Sara M Rothberger
PURPOSE: Multiple sclerosis is a degenerative neurological disease that affects 2.1 million people worldwide. There is no cure, but an expanding body of research supports the positive impact of physical activity and suggests physical activity has benefits for the individual's psychological and physical well-being. MATERIAL AND METHODS: Using Self-Determination Theory as a framework, mixed methods with a focus on qualitative interviews were used to explore physical activity motivation and benefits with a sample of highly active people with multiple sclerosis (n = 15)...
March 14, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28279480/illness-perceptions-and-changes-in-lifestyle-following-a-gynecological-cancer-diagnosis-a-longitudinal-analysis
#8
Marlou E C L van Broekhoven, Belle H de Rooij, Johanna M A Pijnenborg, M Caroline Vos, Dorry Boll, Roy F P M Kruitwagen, Lonneke V van de Poll-Franse, Nicole P M Ezendam
OBJECTIVE: This study explores patterns of lifestyle change and whether more threatening illness perceptions are associated with lifestyle changes post-treatment for smoking, alcohol consumption and Body Mass Index (BMI) among gynecological cancer patients. METHODS: In total, 395 cancer patients (N=221 endometrial; N=174 ovarian) were included in this secondary analysis of longitudinal data. Lifestyle outcomes were assessed through self-reported questionnaires after initial treatment and 6, 12, and 18months of follow-up...
March 6, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28275457/willingness-to-participate-and-take-risks-in-hiv-cure-research-survey-results-from-400-people-living-with-hiv-in-the-us
#9
EDITORIAL
Karine Dubé, David Evans, Laurie Sylla, Jeff Taylor, Bryan J Weiner, Asheley Skinner, Harsha Thirumurthy, Joseph D Tucker, Stuart Rennie, Sandra B Greene
INTRODUCTION: Participation in early-phase HIV cure studies includes clinical risks with little to no likelihood of clinical benefit. Examining the willingness of people living with HIV to participate is important to guide study design and informed consent. Our study examined the overall willingness of people living with HIV to participate in HIV cure research in the US, focusing on perceived risks and benefits of participation. METHODS: We undertook an online survey of adults living with HIV in the US...
January 1, 2017: Journal of Virus Eradication
https://www.readbyqxmd.com/read/28269212/low-cost-rapid-prototyping-of-liquid-crystal-polymer-based-magnetic-microactuators-for-glaucoma-drainage-devices
#10
Hyunsu Park, Simon John, Hyowon Lee
Glaucoma is one of the leading causes of blindness in the world. Although there is no cure for glaucoma, pharmaceutical or surgical interventions are known to delay the progression of this debilitating disease. In recent years, implantation of glaucoma drainage devices (GDD) have increased due to their ability to manage IOP better than other therapeutic approaches. However, only 50% of the implanted devices remain functional after 5 years often due to biofouling. Here, we report our latest progress towards developing self-clearing GDDs using integrated magnetic microactuators...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28258661/polymerization-mode-of-self-adhesive-dual-cured-dental-resin-cements-light-cured-through-various-restorative-materials
#11
Ji Suk Shim, Jeong Kyung Kang, Nayansi Jha, Jae Jun Ryu
OBJECTIVE: The aim of this study was to investigate the polymerization mode of self-adhesive, dual-cured resin cements light-cured through overlying materials with different degree of translucency by measuring the degree of conversion (DC). MATERIALS AND METHODS: Three kinds of self-adhesive, dual-cured resin cements (G-CEM LinkAce(TM) , Maxcem Elite(TM) , and BisCem(®) ) were light-cured through three different restorative materials that included porcelain-fused metal (PFM), zirconia, and lithium disilicate...
March 4, 2017: Journal of Esthetic and Restorative Dentistry
https://www.readbyqxmd.com/read/28258345/effect-of-pessary-use-on-hydronephrosis-in-women-with-advanced-pelvic-organ-prolapse-a-self-selected-interventional-trial
#12
Christina E Dancz, Daphne Walker, Diane Thomas, Nuzhath Hussain, Begüm Özel
INTRODUCTION AND HYPOTHESIS: The purpose of this study was to determine the proportion of women who demonstrate improvement in hydronephrosis after pessary placement for advanced pelvic organ prolapse (POP). METHODS: This was a planned subset analysis of a prospective study on the prevalence of hydronephrosis in women with advanced POP. Women with anterior or apical POP ≥1 cm past the hymenal remnant were enrolled and screened for hydronephrosis. All were offered expectant management, pessary placement or surgery...
March 3, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28245928/evaluation-of-dental-adhesive-systems-incorporating-an-antibacterial-monomer-eugenyl-methacrylate-egma-for-endodontic-restorations
#13
A Almaroof, S A Niazi, L Rojo, F Mannocci, S Deb
OBJECTIVE: The purpose of this study was to incorporate EgMA, an antibacterial monomer into two commercial dental adhesive systems for their application in endodontic restoration with the aim to disinfect the root canal space before curing and to inhibit bacterial growth on their surfaces after being cured. METHODS: EgMA monomer was added at 20%wt. into the formulation of the single-component self-etch, Clearfil Universal Bond™ (CUB) and into the catalyst and the adhesive components of the total-etch Adper Scotchbond-multipurpose™ (SBMP) adhesive systems...
February 25, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28245276/plasmid-interference-for-curing-antibiotic-resistance-plasmids-in-vivo
#14
Muhammad Kamruzzaman, Shereen Shoma, Christopher M Thomas, Sally R Partridge, Jonathan R Iredell
Antibiotic resistance increases the likelihood of death from infection by common pathogens such as Escherichia coli and Klebsiella pneumoniae in developed and developing countries alike. Most important modern antibiotic resistance genes spread between such species on self-transmissible (conjugative) plasmids. These plasmids are traditionally grouped on the basis of replicon incompatibility (Inc), which prevents coexistence of related plasmids in the same cell. These plasmids also use post-segregational killing ('addiction') systems, which poison any bacterial cells that lose the addictive plasmid, to guarantee their own survival...
2017: PloS One
https://www.readbyqxmd.com/read/28243818/effect-of-radiant-heat-on-conventional-glass-ionomer-cements-during-setting-by-using-a-blue-light-diode-laser-system-445%C3%A2-nm
#15
Dimitrios Dionysopoulos, Kosmas Tolidis, Dimitrios Strakas, Paris Gerasimou, Thrasyvoulos Sfeikos, Norbert Gutknecht
The aim of this in vitro study was to evaluate the effect of radiant heat on surface hardness of three conventional glass ionomer cements (GICs) by using a blue diode laser system (445 nm) and a light-emitting diode (LED) unit. Additionally, the safety of the laser treatment was evaluated. Thirty disk-shaped specimens were prepared of each tested GIC (Equia Fil, Ketac Universal Aplicap and Riva Self Cure). The experimental groups (n = 10) of the study were as follows: group 1 was the control group of the study; in group 2, the specimens were irradiated for 60 s at the top surface using a LED light-curing unit; and in group 3, the specimens were irradiated for 60 s at the top surface using a blue light diode laser system (445 nm)...
February 27, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28239154/anti-trypanosomatid-drug-discovery-an-ongoing-challenge-and-a-continuing-need
#16
REVIEW
Mark C Field, David Horn, Alan H Fairlamb, Michael A J Ferguson, David W Gray, Kevin D Read, Manu De Rycker, Leah S Torrie, Paul G Wyatt, Susan Wyllie, Ian H Gilbert
The WHO recognizes human African trypanosomiasis, Chagas disease and the leishmaniases as neglected tropical diseases. These diseases are caused by parasitic trypanosomatids and range in severity from mild and self-curing to near invariably fatal. Public health advances have substantially decreased the effect of these diseases in recent decades but alone will not eliminate them. In this Review, we discuss why new drugs against trypanosomatids are required, approaches that are under investigation to develop new drugs and why the drug discovery pipeline remains essentially unfilled...
February 27, 2017: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/28238780/ly6-plaur-domain-containing-3-has-a-role-in-the-maintenance-of-colorectal-cancer-stem-like-cells
#17
Liming Wang, Yoshihiko Hirohashi, Tadashi Ogawa, Min Shen, Rui Takeda, Aiko Murai, Eri Yamamoto, Terufumi Kubo, Munehide Nakatsugawa, Takayuki Kanaseki, Tomohide Tsukahara, Toshihiko Nishidate, Kenji Okita, Goro Kutomi, Noriyuki Sato, Ichiro Takemasa, Toshihiko Torigoe
Colorectal carcinoma (CRC) is one of the most frequently diagnosed cancers and the leading cause of cancer-related death for both men and women. Recent studies have revealed that a small sub-population of cancer cells, termed cancer stem-like cells (CSCs)/cancer-initiating cells (CICs), are endowed with tumor-initiating ability, self-renewal ability and differentiation ability. CSCs/CICs are resistant to current therapies including chemotherapy and radiotherapy. Thus, CSCs/CICs are responsible for recurrence and metastasis, and eradication of CSCs/CICs is essential to cure cancer...
February 24, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28236695/investigation-of-the-elastic-modulus-tensile-and-flexural-strength-of-five-skull-simulant-materials-for-impact-testing-of-a-forensic-skin-skull-brain-model
#18
Lisa Falland-Cheung, J Neil Waddell, Kai Chun Li, Darryl Tong, Paul Brunton
Conducting in vitro research for forensic, impact and injury simulation modelling generally involves the use of a skull simulant with mechanical properties similar to those found in the human skull. For this study epoxy resin, fibre filled epoxy resin, 3D-printing filaments (PETG, PLA) and self-cure acrylic denture base resin were used to fabricate the specimens (n=20 per material group), according to ISO 527-2 IBB and ISO20795-1. Tensile and flexural testing in a universal testing machine was used to measure their tensile/flexural elastic modulus and strength...
February 20, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28227442/low-cost-rapid-prototyping-of-liquid-crystal-polymer-based-magnetic-microactuators-for-glaucoma-drainage-devices
#19
Hyunsu Park, Simon John, Hyowon Lee, Hyunsu Park, Simon John, Hyowon Lee, Simon John, Hyowon Lee, Hyunsu Park
Glaucoma is one of the leading causes of blindness in the world. Although there is no cure for glaucoma, pharmaceutical or surgical interventions are known to delay the progression of this debilitating disease. In recent years, implantation of glaucoma drainage devices (GDD) have increased due to their ability to manage IOP better than other therapeutic approaches. However, only 50% of the implanted devices remain functional after 5 years often due to biofouling. Here, we report our latest progress towards developing self-clearing GDDs using integrated magnetic microactuators...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224754/evaluation-of-iso-4049-water-sorption-and-water-solubility-of-resin-cements
#20
Johannes A Müller, Nadja Rohr, Jens Fischer
The aim of this study was to evaluate the water sorption and solubility test design of ISO 4049 for resin cements. Sorption and solubility of six dual-curing resin cements [RelyX Unicem 2 Automix (RUN), Multilink Speed CEM (MLS), Panavia SA Plus (PSA), RelyX Ultimate (RUL), Multilink Automix (MLA), and Panavia V5 (PV5)] were analyzed by storage in distilled water after dual-curing. In addition, sorption and solubility during thermal cycling were assessed with self-cured and dual-cured specimens. After water storage, all cements revealed sorption in the range of 30 μg mm(-3) except for PV5, for which sorption was markedly lower (mean ± SD = 20...
February 21, 2017: European Journal of Oral Sciences
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