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https://www.readbyqxmd.com/read/28729371/geographic-atrophy-phenotype-identification-by-cluster-analysis
#1
Jordi Monés, Marc Biarnés
BACKGROUND/AIMS: To identify ocular phenotypes in patients with geographic atrophy secondary to age-related macular degeneration (GA) using a data-driven cluster analysis. METHODS: This was a retrospective analysis of data from a prospective, natural history study of patients with GA who were followed for ≥6 months. Cluster analysis was used to identify subgroups within the population based on the presence of several phenotypic features: soft drusen, reticular pseudodrusen (RPD), primary foveal atrophy, increased fundus autofluorescence (FAF), greyish FAF appearance and subfoveal choroidal thickness (SFCT)...
July 20, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28709680/patient-satisfaction-with-laser-sintered-removable-partial-dentures-a-crossover-pilot-clinical-trial
#2
Balqees Almufleh, Elham Emami, Omar Alageel, Fabiana de Melo, Francois Seng, Eric Caron, Samer Abi Nader, Ashwaq Al-Hashedi, Rubens Albuquerque, Jocelyne Feine, Faleh Tamimi
STATEMENT OF PROBLEM: Clinical data regarding newly introduced laser-sintered removable partial dentures (RPDs) are needed before this technique can be recommended. Currently, only a few clinical reports have been published, with no clinical studies. PURPOSE: This clinical trial compared short-term satisfaction in patients wearing RPDs fabricated with conventional or computer-aided design and computer-aided manufacturing (CAD-CAM) laser-sintering technology. MATERIAL AND METHODS: Twelve participants with partial edentulism were enrolled in this pilot crossover double-blinded clinical trial...
July 11, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28709674/accuracy-of-cad-cam-fabricated-removable-partial-dentures
#3
Christin Arnold, Jeremias Hey, Ramona Schweyen, Jürgen M Setz
STATEMENT OF PROBLEM: The conventional fabrication of removable partial dentures (RPDs) is a complex, error-prone, time-consuming, and expensive process. The use of computer-aided design and computer-aided manufacturing (CAD-CAM) techniques, especially rapid prototyping, promises a more effective method for fabricating RPD frameworks. PURPOSE: The purpose of this in vitro study was to evaluate the fit of RPD clasps fabricated by means of 4 different CAD-CAM-systems and to compare those fittings with that of the conventional lost-wax casting technique (LWT)...
July 11, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28705023/helping-hospitals-improve-patient-centeredness-assessing-the-impact-of-feedback-following-a-best-practices-workshop
#4
Christoph Kowalski, William H Yeaton, Kathrin Kuhr, Holger Pfaff
Regularly reported patient surveys are an important dimension of hospital quality management. This study investigates whether providing hospital staff with interim feedback on patient survey results following a best practices workshop can help hospitals improve patient centeredness. Standardized surveys with consecutive patient samples were administered in accredited breast cancer center (BCC) hospitals in one German state (18 million inhabitants), over a 6-month period, in 2012. Two studies were conducted by applying a combination of regression point displacement (RPD) and interrupted time series (ITS) designs...
June 2017: Evaluation & the Health Professions
https://www.readbyqxmd.com/read/28702749/evaluation-of-different-surgical-methods-in-treating-recurrent-patella-dislocation-after-three-dimensional-reconstruction
#5
Hao Du, Xiao-Xiao Tian, Fa-Qi Guo, Xiang-Ming Li, Tao-Tao Ji, Bin Li, Tong-Sen Li
PURPOSE: Recurrent patella dislocation (RPD) is the most common complication of patellar instability. The effects of different surgical techniques on the outcome of RPD treatments remain unclear. This study was conducted to compare the effects of three surgical techniques in treating RPD by three-dimensional (3D) reconstruction from computed tomography (CT) scans. METHODS: Sixty-eight patients with RPD and no previous surgical treatments who attended our hospital between October 2010 and 2013 were enrolled and randomly assigned into three groups: (1) medial patellofemoral ligament (MPFL) reconstruction and medial patellar retinaculum (MPR) plication group; (2) lateral patellar retinaculum (LPR) release and MPR plication group; and (3) MPFL reconstruction and LPR release group...
July 12, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28697645/biomechanical-investigation-of-prolonged-driving-in-an-ergonomically-designed-truck-seat-prototype
#6
Michelle Cardoso, Colin McKinnon, Dan Viggiani, Michel J Johnson, Jack P Callaghan, Wayne J Albert
A postural evaluation during a prolonged driving task was conducted to determine the ergonomic validity of a new freely adjustable truck seat prototype. Twenty participants were recruited to perform two 2-hour simulated driving sessions. Postures were assessed using motion capture, accelerometers and pressure pads. Subjective discomfort was also monitored in 15-minute increments using ratings of perceived discomfort (RPD) and the automotive seating discomfort questionnaire (ASDQ). Participants had a more neutral spine posture during the first hour of the drive and reported lower RPDs while sitting in the prototype...
July 11, 2017: Ergonomics
https://www.readbyqxmd.com/read/28697204/preliminary-clinical-application-of-removable-partial-denture-frameworks-fabricated-using-computer-aided-design-and-rapid-prototyping-techniques
#7
Hongqiang Ye, Jing Ning, Man Li, Li Niu, Jian Yang, Yuchun Sun, Yongsheng Zhou
PURPOSE: The aim of this study was to explore the application of computer-aided design and rapid prototyping (CAD/RP) for removable partial denture (RPD) frameworks and evaluate the fitness of the technique for clinical application. MATERIALS AND METHODS: Three-dimensional (3D) images of dentition defects were obtained using a lab scanner. The RPD frameworks were designed using commercial dental software and manufactured using selective laser melting (SLM). A total of 15 cases of RPD prostheses were selected, wherein each patient received two types of RPD frameworks, prepared by CAD/RP and investment casting...
July 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/28666108/effect-of-oregano-essential-oil-supplementation-to-a-reduced-protein-amino-acid-supplemented-diet-on-meat-quality-fatty-acid-composition-and-oxidative-stability-of-longissimus-thoracis-muscle-in-growing-finishing-pigs
#8
Chuanshang Cheng, Zuhong Liu, Yuanfei Zhou, Hongkui Wei, Xiaming Zhang, Mao Xia, Zhao Deng, Yi Zou, Siwen Jiang, Jian Peng
This study investigated the effects of reduced-protein, amino acid-supplemented diet supplementation with oregano essential oil (OEO) in pigs, from growing period to slaughter, on the meat quality, fatty acid composition, and oxidative stability of Longissimus thoracis (LT) muscle. Thirty-six barrows were randomly divided into three experimental treatments, namely, normal protein diet (NPD), reduced-protein, amino acid-supplemented diet (RPD), and identical RPD supplemented (250mg/kg feed) with OEO (OEO) treatments...
June 23, 2017: Meat Science
https://www.readbyqxmd.com/read/28664986/betaine-and-arginine-supplementation-of-low-protein-diets-improves-plasma-lipids-but-does-not-affect-hepatic-fatty-acid-composition-and-related-gene-expression-profiling-in-pigs
#9
Marta S Madeira, Eva A Rolo, Paula A Lopes, Denis A Ramos, Cristina M Alfaia, Virgínia M R Pires, Susana V Martins, Rui M A Pinto, José A M Prates
BACKGROUND: The individual and combined effects of betaine and arginine supplemented to reduced protein diets were investigated on plasma metabolites, hepatic fatty acid composition and mRNA levels of lipid-sensitive factors in commercial pigs. Betaine has previously been shown to reduce carcass fat deposition and arginine improves meat quality of finishing pigs. Forty male crossbred pigs were randomly assigned to one of five diets (n=8): 160 g kg(-1) of crude protein (NPD), 130 g kg(-1) of crude protein (RPD), RPD with 3...
June 30, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28661027/silica-scaffold-with-shifted-plumber-s-nightmare-networks-and-the-interconversion-to-diamond-networks
#10
Wenting Mao, Xin Cao, Qingqing Sheng, Lu Han, Shunai Che
The bicontinuous structures with hyperbolic surfaces have been found in a variety of natural and synthetic systems. Here, we present the synthesis and structural study of the shifted double-primitive networks, which is known as the rare "plumber's nightmare", and its interconversion to diamond-networks. The scaffold was fabricated by self-assembly of the amphiphilic triblock terpolymer and silica precursors. Electron crystallography indicates that the structure consists of two sets of hollow primitive-networks shifted along 0...
June 29, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28656121/quantitative-and-qualitative-characterization-of-gentiana-rigescens-franch-gentianaceae-on-different-parts-and-cultivations-years-by-hplc-and-ftir-spectroscopy
#11
Lu-Ming Qi, Ji Zhang, Yan-Li Zhao, Zhi-Tian Zuo, Hang Jin, Yuan-Zhong Wang
Gentiana rigescens Franch (Gentianaceae) is a famous medicinal plant for treatments of rheumatism, convulsion, and jaundice. Comprehensive investigation of different parts and cultivation years of this plant has not yet been conducted. This study presents the quantitative and qualitative characterization of iridoid glycosides from G. rigescens performed by HPLC and FTIR spectroscopy techniques. The accumulations of loganic acid, swertiamarin, gentiopicroside, and sweroside were determined. Results indicated that their content and distribution in different parts and cultivation years exhibit great variations...
2017: Journal of Analytical Methods in Chemistry
https://www.readbyqxmd.com/read/28652455/rapid-progressive-disease-after-nivolumab-therapy-in-three-patients-with-metastatic-renal-cell-carcinoma
#12
Yuki Kobari, Tsunenori Kondo, Toshio Takagi, Kenji Omae, Hayakazu Nakazawa, Kazunari Tanabe
BACKGROUND/AIM: Rapid progressive disease (RPD), accelerated tumour growth immediate after the initiation of immune checkpoint inhibitor therapy, has been reported in melanoma and lung cancer. Herein, we describe 3 cases of RPD during the initial phase of nivolumab treatment for metastatic renal cell carcinoma. PATIENTS AND METHODS: The first and second patients received nivolumab in the fourth-line setting. The third patient received nivolumab therapy as third-line treatment...
July 2017: In Vivo
https://www.readbyqxmd.com/read/28647437/inhibitory-control-is-not-lateralized-in-parkinson-s-patients
#13
G Mirabella, M Fragola, G Giannini, N Modugno, Daniel Lakens
Parkinson's disease (PD) is often characterized by asymmetrical symptoms, which are more prominent on the side of the body contralateral to the most extensively affected brain hemisphere. Therefore, lateralized PD presents an opportunity to examine the effects of asymmetric subcortical dopamine deficiencies on cognitive functioning. As it has been hypothesized that inhibitory control relies upon a right-lateralized pathway, we tested whether left-dominant PD (LPD) patients suffered from a more severe deficit in this key executive function than right-dominant PD patients (RPD)...
June 22, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28613056/-a-preliminary-study-on-the-forming-quality-of-titanium-alloy-removable-partial-denture-frameworks-fabricated-by-selective-laser-melting
#14
Y F Liu, H Yu, W N Wang, B Gao
Objective: To evaluate the processing accuracy, internal quality and suitability of the titanium alloy frameworks of removable partial denture (RPD) fabricated by selective laser melting (SLM) technique, and to provide reference for clinical application. Methods: The plaster model of one clinical patient was used as the working model, and was scanned and reconstructed into a digital working model. A RPD framework was designed on it. Then, eight corresponding RPD frameworks were fabricated using SLM technique...
June 9, 2017: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/28593728/association-of-risk-genotypes-of-arms2-loc387715-a69s-and-cfh-y402h-with-age-related-macular-degeneration-with-and-without-reticular-pseudodrusen-a-meta-analysis
#15
REVIEW
Mohammad Hossein Jabbarpoor Bonyadi, Mehdi Yaseri, Homayoun Nikkhah, Mortaza Bonyadi, Masoud Soheilian
To pool the results of published data regarding association of ARMS2/LOC387715 A69S, CFH Y402H and CFH I62V genotypes with age-related macular degeneration (AMD) with and without reticular pseudodrusen (RPD). The results of this pooled data used to estimate the contribution of each of these genes in the pathogenesis of RPD. Heterogeneity of studies was evaluated using Cochran Q-test and I(2) index. To modify the heterogeneity in the variables, we used the random effects model. Meta-analysis was performed using STATA...
June 8, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28590092/additive-manufacturing-a-novel-method-for-fabricating-cobalt-chromium-removable-partial-denture-frameworks
#16
Frank Alifui-Segbaya, Robert John Williams, Roy George
Additive manufacturing (AM) often referred to as 3D printing (3DP) has shown promise of being significantly viable in the construction of cobalt-chromium removable partial denture (RPD) frameworks. The current paper seeks to discuss AM technologies (photopolymerization processes and selective laser melting) and review their scope. The review also discusses the clinical relevance of cobalt-chromium RPD frameworks. All relevant publications in English over the last 10 years, when the first 3D-printed RPD framework was reported, are examined...
June 2017: European Journal of Prosthodontics and Restorative Dentistry
https://www.readbyqxmd.com/read/28573565/concentration-estimation-of-heavy-metal-in-soils-from-typical-sewage-irrigation-area-of-shandong-province-china-using-reflectance-spectroscopy
#17
Fei Wang, Chunfang Li, Jining Wang, Wentao Cao, Quanyuan Wu
Since sewage irrigation can markedly disturb the status of heavy metals in soils, a convenient and accurate technique for heavy metal concentration estimation is of utmost importance in the cropland using wastewater for irrigation. This study therefore assessed the feasibility of visible and near infrared reflectance (VINR) spectroscopy for predicting heavy metal contents including Cr, Cu, Ni, Pb, Zn, As, Cd, and Hg in the north plain of Longkou city, Shandong Province, China. A total of 70 topsoil samples were taken for in situ spectra measurement and chemical analysis...
July 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28564702/associations-between-%C3%AE-peripapillary-atrophy-and-reticular-pseudodrusen-in-early-age-related-macular-degeneration
#18
Aakriti Garg, Dana M Blumberg, Lama A Al-Aswad, Maris Oll, Suzanne Yzer, Max Forbes, Rando L Allikmets, Srilaxmi Bearelly
Purpose: Choroidal thinning has been associated with reticular pseudodrusen (RPD) and β-peripapillary atrophy (β-PPA), which have been linked to normal-tension glaucoma (NTG). This analysis sought to determine whether RPD are independently associated with β-PPA in early AMD patients. Secondary outcomes included the association of RPD and preexisting diagnosis of glaucoma, cup-to-disc ratio (CDR), subfoveal choroidal thickness (SFCT), and IOP. Methods: This prospective cross-sectional study examined 78 age- and sex-matched early AMD patients: 43 RPD patients (63 eyes) and 35 non-RPD patients (64 eyes)...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28561993/removable-partial-denture-alloys-processed-by-laser-sintering-technique
#19
Omar Alageel, Mohamed-Nur Abdallah, Ammar Alsheghri, Jun Song, Eric Caron, Faleh Tamimi
Removable partial dentures (RPDs) are traditionally made using a casting technique. New additive manufacturing processes based on laser sintering has been developed for quick fabrication of RPDs metal frameworks at low cost. The objective of this study was to characterize the mechanical, physical, and biocompatibility properties of RPD cobalt-chromium (Co-Cr) alloys produced by two laser-sintering systems and compare them to those prepared using traditional casting methods. The laser-sintered Co-Cr alloys were processed by the selective laser-sintering method (SLS) and the direct metal laser-sintering (DMLS) method using the Phenix system (L-1) and EOS system (L-2), respectively...
May 31, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28558680/arginine-supplementation-modulates-pig-plasma-lipids-but-not-hepatic-fatty-acids-depending-on-dietary-protein-level-with-or-without-leucine
#20
Marta Sofia Morgado Dos Santos Madeira, Eva Sofia Alves Rolo, Virgínia Maria Rico Pires, Cristina Maria Riscado Pereira Mateus Alfaia, Diogo Francisco Maurício Coelho, Paula Alexandra Antunes Brás Lopes, Susana Isabel Vargas Martins, Rui Manuel Amaro Pinto, José António Mestre Prates
BACKGROUND: In the present study, the effect of arginine and leucine supplementation, and dietary protein level, were investigated in commercial crossbred pigs to clarify their individual or combined impact on plasma metabolites, hepatic fatty acid composition and mRNA levels of lipid sensitive factors. The experiment was conducted on fifty-four entire male pigs (Duroc × Pietrain × Large White × Landrace crossbred) from 59 to 92 kg of live weight. Each pig was randomly assigned to one of six experimental treatments (n = 9)...
May 30, 2017: BMC Veterinary Research
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