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Segundo J González, Blaise Mooney, Hui-Yi Lin, Xiuhua Zhao, John V Kiluk, Nazanin Khakpour, Christine Laronga, M Catherine Lee
Ultrasound (US) allows real-time tumor assessment. We evaluated the volumetric limits of 2-D and 3-D US, compared with magnetic resonance imaging (MRI), with a prospective institutional review board-approved clinical evaluation of US-to-MRI volumetric correlation. US images of pre- and post-neoadjuvant breast cancers were obtained. Volume discrepancy was evaluated with the non-parametric Wilcoxon signed-rank test. Expected inter-observer variability <14% was evaluated as relative paired difference (RPD); clinical relevance was gauged with the volumetric standard error of the mean (SEM)...
February 7, 2017: Ultrasound in Medicine & Biology
Zhihong Hu, Yue Shi, Kiran Nandanan, Srinivas R Sadda
Historically, regular drusen and geographic atrophy (GA) have been recognized as the hallmarks of nonneovascular age-related macular degeneration (AMD). Recent imaging developments have revealed another distinct nonneovascular AMD phenotype, reticular pseudodrusen (RPD). We develop an approach to semiautomatically quantify retinal surfaces associated with various AMD lesions (i.e., regular drusen, RPD, and GA) in spectral domain (SD) optical coherence tomography (OCT) images. More specifically, a graph-based algorithm was used to segment multiple retinal layers in SD-OCT volumes...
January 2017: Neurophotonics
Tibor Janči, Davor Valinger, Jasenka Gajdoš Kljusurić, Lara Mikac, Sanja Vidaček, Mile Ivanda
This study was focused on development of a rapid and sensitive method for histamine determination in fish based on Surface Enhanced Raman Spectroscopy (SERS) using simple and widely available silver colloid SERS substrate. Extraction of histamine with 0.4M perchloric acid and purification with 1-butanol significantly shortened sample preparation (30min) and provided clear SERS spectra with characteristic Raman bands of histamine. Principal component analysis effectively distinguished SERS spectra of fish samples with different histamine content...
June 1, 2017: Food Chemistry
M I González-Martín, I Revilla, A M Vivar-Quintana, E V Betances Salcedo
This study analyses the presence of pesticides in 106 samples of raw propolis from Spain and Chile. The components detected and quantified using gas chromatography mass spectrometry were as follows: triamidefon present in 70.1% of the samples with concentrations between 0.35 and 42.17mg/kg, and dicofol detected in 7.5% of the samples with concentrations between 0.39 and 2.83mg/kg. Diclorofluanid, procymidone, folpet, propham and metazachlor were also detected but only in a small number of samples. Near infrared spectroscopy with a remote reflectance fibre-optic probe was used to detect samples contaminated with triadimefon via partial least squares discriminant, with a R(2) value of 0...
April 1, 2017: Talanta
W A Goodall, A C Greer, N Martin
Removable partial dentures (RPDs) are widely used to replace missing teeth in order to restore both function and aesthetics for the partially dentate patient. Conventional RPD design is frequently bilateral and consists of a major connector that bridges both sides of the arch. Some patients cannot and will not tolerate such an extensive appliance. For these patients, bridgework may not be a predictable option and it is not always possible to provide implant-retained restorations. This article presents unilateral RPDs as a potential treatment modality for such patients and explores indications and contraindications for their use, including factors relating to patient history, clinical presentation and patient wishes...
January 27, 2017: British Dental Journal
Josep Badal, Marc Biarnés, Jordi Monés
PURPOSE: To describe the appearance of reticular pseudodrusen on multicolor imaging and to evaluate its diagnostic accuracy as compared with the two modalities that may be considered the current reference standard, blue light and infrared imaging. METHODS: Retrospective study in which all multicolor images (constructed from images acquired at 486 nm-blue, 518 nm-green and 815 nm-infrared) of 45 consecutive patients visited in a single center was reviewed. Inclusion criteria involved the presence of >1 reticular pseudodrusen on a 30° × 30° image centered on the fovea as seen with the blue light channel derived from the multicolor imaging...
January 21, 2017: International Ophthalmology
Maria Vittoria Cicinelli, Alessandro Rabiolo, Alessandro Marchese, Luigi de Vitis, Adriano Carnevali, Lea Querques, Francesco Bandello, Giuseppe Querques
AIMS: To describe the vascular changes in patients affected by non-neovascular age-related macular degeneration (AMD), featuring reticular pseudodrusen (RPD), drusen, or both RPD and drusen by means of optical coherence tomography angiography (OCT-A). METHODS: Cross-sectional observational case series. Patients with non-neovascular AMD presenting at the Medical Retina Service of the Department of Ophthalmology, University Vita-Salute San Raffaele in Milan were recruited...
January 5, 2017: British Journal of Ophthalmology
Cholpajsorn Junhom, Natthida Weerapreeyakul, Waraporn Tanthanuch, Kanjana Thumanu
We evaluated the feasibility of FTIR microspectroscopy combined with partial least squares regression (PLS-R) for determination of resistance in HepG2 cells. Cell viability testing was performed using neutral red assay for the concentration of cisplatin resulting in 50% antiproliferation (IC50). The resistance index (RI) is the ratio of the IC50 in resistant HepG2 cells vs. parental HepG2 cells. Principal component and unsupervised hierarchical cluster analyses were applied and a differentiation of samples of cells (parental, 1...
January 3, 2017: Experimental Cell Research
E Shekel, D Epstein, D Levin
PURPOSE: To determine the tissue equivalence of a brass mesh bolus (RPD) in the setting of a reconstructed chest wall irradiation METHODS: We measured breast skin dose delivered by a tangential field plan on an anthropomorphic phantom using Mosfet and nanoDot (Landauer) dosimeters in five different locations on the breast. We also measured skin dose using no bolus, 5mm and 10 mm superflab bolus. In the Eclipse treatment planning system (Varian, Palo Alto, CA) we calculated skin dose for different bolus thicknesses, ranging from 0 to 10 mm, in order to evaluate which calculation best matches the brass mesh measurements, as the brass mesh cannot be simulated due to artefacts...
June 2016: Medical Physics
Canan Bural, Begum Buzbas, Sebnem Ozatik, Gulsen Bayraktar, Yusuf Emes
This case report describes the fabrication of a distal extension removable partial denture (RPD) of a 65-year-old man with implant support. Loss of fibroelasticity of the peripheral tissues and reduced mandibular vestibular sulcular depth due to a previous surgical resection and radiotherapy at the right side were the main clinical factors that created difficulty for denture retention and stability. The fabrication of a mandibular RPD supported by anterior teeth and two bilaterally placed implants in the molar area to convert from Kennedy Class 1 design to Kennedy Class 3 implant-bounded RPD is reported...
October 2016: European Journal of Dentistry
Mark D Girgis, Mazen S Zenati, Jennifer Steve, David L Bartlett, Amer Zureikat, Herbert J Zeh, Melissa E Hogg
INTRODUCTION: The aim was to evaluate the impact of obesity on perioperative outcomes in patients undergoing robotic pancreaticoduodenectomy (RPD) compared to open pancreaticoduodenectomy (OPD). METHODS: A retrospective review of all pancreaticoduodenectomies from 9/2011 to 4/2015 was performed. Obesity was defined as body mass index (BMI) > 30 kg/m(2). RESULTS: Of 474 pancreaticoduodenectomies performed: RPD = 213 (45%) and OPD = 261 (55%)...
December 27, 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
Matthew T McMillan, Amer H Zureikat, Melissa E Hogg, Stacy J Kowalsky, Herbert J Zeh, Michael H Sprys, Charles M Vollmer
Importance: The adoption of robotic pancreatoduodenectomy (RPD) is gaining momentum; however, its impact on major outcomes, including pancreatic fistula, has yet to be adequately compared with open pancreatoduodenectomy (OPD). Objective: To demonstrate that use of RPD does not increase the incidence of clinically relevant pancreatic fistula (CR-POPF) compared with OPD. Design, Setting, and Participants: Data were accrued from 2846 patients who underwent pancreatoduodenectomies (OPDs, n = 2661; RPDs, n = 185), performed by 51 surgeons at 17 institutions worldwide (2003-2015)...
December 28, 2016: JAMA Surgery
Can Li, Fei Wang, Lixuan Zang, Hengchang Zang, Manel Alcalà, Lei Nie, Mingyu Wang, Lian Li
Nowadays, as a powerful process analytical tool, near infrared spectroscopy (NIRS) has been widely applied in process monitoring. In present work, NIRS combined with multivariate analysis was used to monitor the ethanol precipitation process of fraction I+II+III (FI+II+III) supernatant in human albumin (HA) separation to achieve qualitative and quantitative monitoring at the same time and assure the product's quality. First, a qualitative model was established by using principal component analysis (PCA) with 6 of 8 normal batches samples, and evaluated by the remaining 2 normal batches and 3 abnormal batches...
March 15, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Gifty E Acquah, Brian K Via, Oladiran O Fasina, Lori G Eckhardt
Fourier transform infrared reflectance (FTIR) spectroscopy has been used to predict properties of forest logging residue, a very heterogeneous feedstock material. Properties studied included the chemical composition, thermal reactivity, and energy content. The ability to rapidly determine these properties is vital in the optimization of conversion technologies for the successful commercialization of biobased products. Partial least squares regression of first derivative treated FTIR spectra had good correlations with the conventionally measured properties...
2016: Journal of Analytical Methods in Chemistry
Cheng Li, Tianlun Zhao, Cong Li, Lei Mei, En Yu, Yating Dong, Jinhong Chen, Shuijin Zhu
Near infrared (NIR) spectroscopy combined with Monte Carlo uninformative variable elimination (MC-UVE) and nonlinear calibration methods employed to determine gossypol content in cottonseeds were investigated. The reference method was performed by high performance liquid chromatography coupled to an ultraviolet detector (HPLC-UV). MC-UVE was employed to extract the effective information from the full NIR spectra. Nonlinear calibration methods were applied to establish the models compared with the linear method...
April 15, 2017: Food Chemistry
Christian G Kirchler, Cornelia K Pezzei, Krzysztof B Beć, Sophia Mayr, Mika Ishigaki, Yukihiro Ozaki, Christian W Huck
In the present work the performances of one benchtop and two different types of miniaturized near-infrared (NIR)-spectrometers were tested and compared for the first time by the determination of the rosmarinic acid (RA) content of dried and powdered Rosmarini folium. The recorded NIR spectra were utilized in hyphenation with multivariate data analysis (MVA) to calculate Partial Least Squares (PLS) regression models. Quality parameters obtained from Cross Validation (CV) revealed that the benchtop NIR-device "NIRFlex N-500 FT-NIR spectrometer" achieved the best result with a R(2) of 0...
December 15, 2016: Analyst
Long Peng, Shengrong Lin, Yong Li, Weidong Xiao
BACKGROUND: Although robotic pancreaticoduodenectomy (RPD) has been successfully performed since 2003, its advantages over open pancreaticoduodenectomy (OPD) are still uncertain. The aim of this systematic review and meta-analysis was to compare the clinical outcomes of RPD to those of OPD. METHODS: A systematic literature review was performed to identify RPD versus OPD comparative studies published between January 2003 and January 2016. Intraoperative outcomes, post-operative outcomes and oncologic safety were evaluated...
December 7, 2016: Surgical Endoscopy
Cheolmin Yun, Jaemoon Ahn, Minjung Kim, Soon-Young Hwang, Seong-Woo Kim, Jaeryung Oh
Purpose: The purpose of this study was to investigate the relationship between the ocular perfusion pressure (OPP) and subfoveal choroidal thickness (CT) in eyes with early age-related macular degeneration (AMD) with or without reticular pseudodrusen (RPD). Methods: We evaluated the clinical history, blood pressure parameters, fundus photography, and optical coherence tomography images of consecutive patients with early AMD. We calculated the mean OPP from blood pressure and intraocular pressure...
December 1, 2016: Investigative Ophthalmology & Visual Science
Ju-Won Eom, Young-Jun Lim, Myung-Joo Kim, Ho-Beom Kwon
STATEMENT OF PROBLEM: Whether the implant abutment in implant-assisted removable partial dentures (IARPDs) functions as a natural removable partial denture (RPD) tooth abutment is unknown. PURPOSE: The purpose of this 3-dimensional finite element study was to analyze the biomechanical behavior of implant crown, bone, RPD, and IARPD. MATERIAL AND METHODS: Finite element models of the partial maxilla, teeth, and prostheses were generated on the basis of a patient's computed tomographic data...
November 30, 2016: Journal of Prosthetic Dentistry
Khoirul Muslim, Maury A Nussbaum
Traditional posterior load carriage (PLC), typically performed without the use of an assistive device, is associated with a high prevalence of low back pain (LBP). However, there are few studies that have evaluated potential interventions to reduce exposures to LBP risk factors. This work examined the effects of a simple, potentially low-cost intervention using an assistive device (i.e., carrying aid) on exposures to factors related to LBP risk during PLC. Torso kinematics and kinetics, slip risk, and ratings of perceived discomfort (RPD) were obtained during simulated PLC on a walkway...
March 2017: Applied Ergonomics
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