keyword
MENU ▼
Read by QxMD icon Read
search

Cyclops

keyword
https://www.readbyqxmd.com/read/29450655/transcription-factors-network-in-root-endosymbiosis-establishment-and-development
#1
REVIEW
Issa Diédhiou, Diaga Diouf
Root endosymbioses are mutualistic interactions between plants and the soil microorganisms (Fungus, Frankia or Rhizobium) that lead to the formation of nitrogen-fixing root nodules and/or arbuscular mycorrhiza. These interactions enable many species to survive in different marginal lands to overcome the nitrogen-and/or phosphorus deficient environment and can potentially reduce the chemical fertilizers used in agriculture which gives them an economic, social and environmental importance. The formation and the development of these structures require the mediation of specific gene products among which the transcription factors play a key role...
February 15, 2018: World Journal of Microbiology & Biotechnology
https://www.readbyqxmd.com/read/29400462/copper-ii-triflate-as-a-reusable-catalyst-for-the-synthesis-of-trans-4-5-diamino-cyclopent-2-enones-in-water
#2
Rafael F A Gomes, Nuno R Esteves, Jaime A S Coelho, Carlos A M Afonso
Trans-4,5-diamino-cyclopent-2-enones (CP) are usually prepared by Lewis acid-catalyzed condensation of furfural and a secondary amine in an organic solvent. The reaction proceeds through the formation of a Stenhouse salt (SS) intermediate followed by an electrocyclization reaction to afford the desired CP. Herein, we described the use of Cu(OTf)2 as a very efficient catalyst for the synthesis of CP in water at room temperature. Furthermore, the mild reaction conditions, catalyst reusability and outstanding functional group tolerance suggests that this CP platform can be further used in chemical biology...
February 5, 2018: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29388660/effective-and-diastereoselective-preparation-of-dispiro-cyclopent-3-ene-bisoxindoles-via-novel-3-2-annulation-of-isoindigos-and-mbh-carbonates
#3
Hong-Xia Ren, Lin Peng, Xiang-Jia Song, Li-Guo Liao, Ying Zou, Fang Tian, Li-Xin Wang
A novel and diastereoselective [3 + 2] annulation of isoindigos and Morita-Baylis-Hillman carbonates has been developed for the highly efficient and one-step preparation of highly steric dispiro[cyclopent-3'-ene]bisoxindoles with two all-carbon quaternary spirocenters and three adjacent cycles in excellent yields (up to >99%) and diastereoselectivities (up to >20 : 1) under mild conditions within a few minutes. A series of dispiro[cyclopent-3'-ene]bisoxindoles were obtained and scale-up experiment was conducted with excellent results demonstrating the potential applications of this protocol...
February 1, 2018: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/29381352/design-and-mechanism-of-s-3-amino-4-difluoromethylenyl-cyclopent-1-ene-1-carboxylic-acid-a-highly-potent-%C3%AE-aminobutyric-acid-aminotransferase-inactivator-for-the-treatment-of-addiction
#4
Jose I Juncosa, Kenji Takaya, Hoang V Le, Matthew J Moschitto, Pathum M Weerawarna, Romila Mascarenhas, Dali Liu, Stephen L Dewey, Richard B Silverman
γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the central nervous system. Inhibition of GABA aminotransferase (GABA-AT), a pyridoxal 5'-phosphate (PLP)-dependent enzyme that degrades GABA, has been established as a possible strategy for the treatment of substance abuse. The raised GABA levels that occur as a consequence of this inhibition have been found to antagonize the rapid release of dopamine in the ventral striatum (nucleus accumbens) that follows an acute challenge by an addictive substance...
January 30, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29323768/copper-catalyzed-enantioselective-arylative-desymmetrization-of-prochiral-cyclopentenes-with-diaryliodonium-salts
#5
Hua Wu, Qian Wang, Jieping Zhu
A copper-catalyzed enantioselective arylative desymmetrization of prochiral cyclopentenes with diaryliodonium salts was developed. In the presence of a catalytic amount of the in situ generated chiral copper-bisoxazoline complex, reaction of 4-substituted or 4,4-disubstituted cyclopent-1-enes with the diaryliodonium hexafluoroarsenate afforded the chiral arylated products in good yields with excellent enantioselectivities. Use of the cyclohexyl-containing Box ligand was essential for the high enantioselectivity...
January 11, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29287288/-the-cyclops-breast-as-result-after-resection-of-a-large-recurrence-of-breast-cancer-a-rare-case-report
#6
Katarina Teresa Wishart, Dorrit Winterholer, Inja Bogdan, Elmar Fritsche
No abstract text is available yet for this article.
December 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/29204489/the-cyclops-lesion-after-bicruciate-retaining-total-knee-replacement
#7
Mark A Klaassen, Jerry L Aikins
The cyclops lesion is a localized anterior arthrofibrosis most commonly seen following anterior cruciate ligament reconstruction. The lesion forms at the anterior cruciate ligament insertion creating a painful extension block between femoral intercondylar notch and tibial plateau. We present 2 cases (3 knees) in which cyclops lesions appeared atypically following bicruciate-retaining total knee replacement. Two lesions occurred in a single patient following bilateral knee replacement. One lesion occurred in an active sportswoman...
December 2017: Arthroplasty Today
https://www.readbyqxmd.com/read/29200384/-from-cyclops-to-reality-a-fresh-look-at-the-genetics-of-holoprosencephaly
#8
Valérie Dupé, Christèle Dubourg, Marie de Tayrac, Véronique David
No abstract text is available yet for this article.
November 2017: Médecine Sciences: M/S
https://www.readbyqxmd.com/read/29198590/clinical-outcomes-of-single-anteromedial-bundle-biologic-augmentation-sambba-technique-for-anterior-cruciate-ligament-reconstruction-with-consideration-of-tibial-remnant-size
#9
Hervé Ouanezar, William G Blakeney, Levi Reina Fernandes, Amrut Borade, Charles Latrobe, Eduardo Frois Temponi, Bertrand Sonnery-Cottet
PURPOSE: The primary aim of this study was to evaluate the functional outcomes, knee stability, complications, and reoperations associated with anatomic anterior cruciate ligament (ACL) reconstruction using the single anteromedial bundle biological augmentation (SAMBBA) technique in a consecutive series of 128 patients with a minimum follow-up of 24 months. A secondary aim was to compare larger preserved ACL remnants with smaller preserved remnants. METHODS: Patients who underwent primary anatomic ACL reconstruction using the SAMBBA technique from July 2013 to October 2014 were analyzed...
November 30, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29187569/dynamics-of%C3%A2-lotus-japonicus%C3%A2-ethylene-production-in-response-to-compatible-nod-factor
#10
Dugald Elgin Reid, Huijun Liu, Simon Kelly, Yasuyuki Kawaharada, Terry Mun, Stig U Andersen, Guilhem J Desbrosses, Jens Stougaard
Establishment of symbiotic nitrogen-fixation in legumes is regulated by the plant hormone ethylene, but it has remained unclear whether and how its biosynthesis is regulated by the symbiotic pathway. We established a sensitive ethylene detection system for Lotus japonicus and found that ethylene production increased as early as six hours after inoculation with Mesorhizobium loti. This ethylene response was dependent on Nod factor production by compatible rhizobia. Analyses of nodulation mutants showed that perception of Nod factor was required for ethylene emission, while downstream transcription factors including CYCLOPS, NIN and ERN1 were not required for this response...
November 29, 2017: Plant Physiology
https://www.readbyqxmd.com/read/29177328/synthesis-of-cyclopent-2-enones-from-furans-using-a-nebulizer-based-continuous-flow-photoreactor
#11
Georgios I Ioannou, Tamsyn Montagnon, Dimitris Kalaitzakis, Spiros A Pergantis, Georgios Vassilikogiannakis
A series of hydroxycyclopent-2-enones and methoxycyclopent-2-enones have been synthesized in a single operation from simple furan substrates using an innovative continuous flow nebulizer system (NebPhotOX). Photooxygenation of the furan substrates takes place in an aerosol within the NebPhotOX system.
November 27, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/29158707/a-novel-monocyclic-triterpenoid-and-a-norsesquaterpenol-from-the-aerial-parts-of-suaeda-monoica-forssk-ex-j-f-gmel-with-cell-proliferative-potential
#12
Mansour S Al-Said, Nasir A Siddiqui, Mohamed Ahmed Mukhair, Mohammad K Parvez, Perwez Alam, Mohd Ali, Anzarul Haque
Suaeda monoica Forssk. ex J.F. Gmel (Chenopodiaceae), a mangrove herb, is distributed in tropical Africa, Arabian Peninsula, India, Pakistan, Palestine and Jordan. The plant parts are used to treat sore throat, hepatitis, wounds, rheumatism, paralysis, asthma, snakebites, skin disease and ulcer. Two new phytoconstituents characterized as 13,17-octahydropentalene-4,4,10,23-tetramethyl-17,21-diisopropyl-tetradecahydrocyclo-[a]-phenanthrene-(14), 20(23), 21(30)-trien-5α-ol (SMC-3) and [1,4,4-trimethyl-cyclopent-1(5)-enyl]-9,10,17,21-tetramethyl-9α-ol-16α (17α)-epoxy heptadecan-6,10-dione (SMC-4) belong to the class norsesquaterpenol and monocyclic triterpenoid, respectively, along with two known compounds 3-epi-lupeol (SMC-1) and 4-cyclopentylpyrocatechol (SMC-2) have been isolated from the ethanol extract of aerial parts of S...
November 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/29140250/gdf3-is-required-for-robust-nodal-signaling-during-germ-layer-formation-and-left-right-patterning
#13
Jose L Pelliccia, Granton A Jindal, Rebecca D Burdine
Vertebrate embryonic patterning depends on signaling from Nodal, a TGFβ superfamily member. There are three Nodal orthologs in zebrafish; southpaw directs left-right asymmetries, while squint and cyclops function earlier to pattern mesendoderm. TGFβ member Vg1 is implicated in mesoderm formation but the role of the zebrafish ortholog, Growth differentiation factor 3 (Gdf3), has not been fully explored. We show that zygotic expression of gdf3 is dispensable for embryonic development, while maternally deposited gdf3 is required for mesendoderm formation and dorsal-ventral patterning...
November 15, 2017: ELife
https://www.readbyqxmd.com/read/29110480/lewis-acid-triggered-vinylcyclopropane-cyclopentene-rearrangement
#14
Olga A Ivanova, Alexey O Chagarovskiy, Alexey N Shumsky, Vasiliy D Krasnobrov, Irina I Levina, Igor V Trushkov
We report a mild Lewis acid-induced isomerization of donor-acceptor cyclopropanes, containing an alkenyl moiety and diverse electron-withdrawing group(s) at the adjacent positions, into substituted cyclopentenes. We have found that 1,1,2-trisubstituted cyclopent-3-enes were exclusively obtained in yield of 51 to 99% when cyclopropanes with 2-substituted alkenyl group as a donor underwent isomerization. For cyclopropanes bearing trisubstituted alkenyl group either the corresponding cyclopent-3-enes or isomeric cyclopent-2-enes having two acceptor groups at the C(1) atom were formed, with the reaction selectivity being determined by the applied Lewis acid...
November 7, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29061823/synthesis-of-2-substituted-benzothiazole-derivatives-and-their-in-vitro-anticancer-effects-and-antioxidant-activities-against-pancreatic-cancer-cells
#15
Nuray Uremis, Muhammed Mehdi Uremis, Fatma Inanc Tolun, Mustafa Ceylan, Adem Doganer, Akif Hakan Kurt
Pancreatic cancer is one of the deadliest malignancies characterized by strong resistance to almost all chemotherapeutic agents and radiotherapy. In this study, we aimed to investigate the anticancer effect, enzymatic antioxidant activity [superoxide dismutase (SOD), glutathione peroxidase (GPx)] and total antioxidant capacity (TAC) of synthesized benzothiazole compounds against adenocarcinoma cancer cells (PANC-1). 2-((1S,2S)-2-((E)-4-nitrostyryl)cyclopent-3-en-1-yl)benzo[d]thiazole and 2-((1S,2S)-2-((E)-4-fluorostyryl) cyclopent-3-en-1-yl)benzo[d]thiazole containing 2-substituted benzothiazole group were synthesized in two steps...
November 2017: Anticancer Research
https://www.readbyqxmd.com/read/29059375/translational-co-regulation-of-a-ligand-and-inhibitor-by-a-conserved-rna-element
#16
Andreas Zaucker, Agnieszka Nagorska, Pooja Kumari, Nikolai Hecker, Yin Wang, Sizhou Huang, Ledean Cooper, Lavanya Sivashanmugam, Shruthi VijayKumar, Jan Brosens, Jan Gorodkin, Karuna Sampath
In many organisms, transcriptional and post-transcriptional regulation of components of pathways or processes has been reported. However, to date, there are few reports of translational co-regulation of multiple components of a developmental signaling pathway. Here, we show that an RNA element which we previously identified as a dorsal localization element (DLE) in the 3'UTR of zebrafish nodal-related1/squint (ndr1/sqt) ligand mRNA, is shared by the related ligand nodal-related2/cyclops (ndr2/cyc) and the nodal inhibitors, lefty1 (lft1) and lefty2 mRNAs...
October 20, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29032676/following-the-molecular-mechanism-of-decarbonylation-of-unsaturated-cyclic-ketones-using-bonding-evolution-theory-coupled-with-nci-analysis
#17
Ehsan Zahedi, Samaneh Shaabani, Abolfazl Shiroudi
The synergetic use of bonding evolution theory (BET) and noncovalent interaction (NCI) analysis allows to obtain new insight into the bond breaking/forming processes and electron redistribution along the reaction path to understand the molecular mechanism of a reaction and recognize regions of strong and weak electron pairing. This viewpoint has been considered for cheletropic extrusion of CO from unsaturated cyclic ketones cyclohepta-3,5-dien-1-one CHD, cyclopent-3-en-1-one CPE, and bicyclo[2.2.1]hept-2-en-7-one BCH by using hybrid functional MPWB1K in conjugation with aug-cc-pVTZ basis set...
November 1, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28945515/multiple-nodulation-genes-are-up-regulated-during-establishment-of-reniform-nematode-feeding-sites-in-soybean
#18
Nathan Wayne Redding, Paula Agudelo, Christina E Wells
The semi-endoparastic reniform nematode (Rotylenchulus reniformis) infects over 300 plant species. Females penetrate host roots and induce formation of complex, multinucleate feeding sites called syncytia. While anatomical changes associated with reniform nematode infection are well documented, little is known about their molecular basis. We grew soybean (Glycine max) in a split-root growth system, inoculated half of each root system with R. reniformis, and quantified gene expression in infected and control root tissue at four dates after inoculation...
September 15, 2017: Phytopathology
https://www.readbyqxmd.com/read/28925289/a-new-antifungal-benzoic-acid-ester-from-uvaria-narum
#19
Alka Elizabeth Varghese, Balaji Govindan, Jyothilakshmi Madhavankutty, Antony Thomas Valiyaveetil, Madhusudhanan Karadka, Sabulal Baby
Uvaria narum has been used for gastrointestinal problems, jaundice, fever and skin diseases in traditional and ethnomedical practices. Our preliminary antifungal screening of various leaf extracts of U. narum revealed very good antifungal activity for its acetone extract. Active principle of U. narum leaf acetone extract was isolated by bioactivity-guided fractionation and characterised as a new molecule, 2-E-(2″-oxo-5″-acetoxy cyclopent-3″-en-1″-ylidene) ethyl benzoate, by NMR, IR and mass spectroscopic analyses...
September 19, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28902609/knee-extension-loss-secondary-to-a-cyclops-like-gouty-tophus-a-case-report-and-literature-review
#20
Michael Doany, Nicole Lopez, Andrew Rokito
While gouty arthritis of the knee is not uncommon, associated mechanical block to extension is a rarely seen complication. This report presents a unique case of extension loss due to a single, isolated intra-articular gouty tophus. Only a few similar reports have been described in the literature involving cases that are often initially suspected to be related to inherent structural knee pathology as opposed to a systemic condition or illness.
May 2017: Bulletin of the Hospital for Joint Diseases
keyword
keyword
50778
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"