keyword
MENU ▼
Read by QxMD icon Read
search

Cyclops

keyword
https://www.readbyqxmd.com/read/29204489/the-cyclops-lesion-after-bicruciate-retaining-total-knee-replacement
#1
Mark A Klaassen, Jerry L Aikins
The cyclops lesion is a localized anterior arthrofibrosis most commonly seen following anterior cruciate ligament reconstruction. The lesion forms at the anterior cruciate ligament insertion creating a painful extension block between femoral intercondylar notch and tibial plateau. We present 2 cases (3 knees) in which cyclops lesions appeared atypically following bicruciate-retaining total knee replacement. Two lesions occurred in a single patient following bilateral knee replacement. One lesion occurred in an active sportswoman...
December 2017: Arthroplasty Today
https://www.readbyqxmd.com/read/29200384/-from-cyclops-to-reality-a-fresh-look-at-the-genetics-of-holoprosencephaly
#2
Valérie Dupé, Christèle Dubourg, Marie de Tayrac, Véronique David
No abstract text is available yet for this article.
November 2017: Médecine Sciences: M/S
https://www.readbyqxmd.com/read/29198590/clinical-outcomes-of-single-anteromedial-bundle-biologic-augmentation-sambba-technique-for-anterior-cruciate-ligament-reconstruction-with-consideration-of-tibial-remnant-size
#3
Hervé Ouanezar, William G Blakeney, Levi Reina Fernandes, Amrut Borade, Charles Latrobe, Eduardo Frois Temponi, Bertrand Sonnery-Cottet
PURPOSE: The primary aim of this study was to evaluate the functional outcomes, knee stability, complications, and reoperations associated with anatomic anterior cruciate ligament (ACL) reconstruction using the single anteromedial bundle biological augmentation (SAMBBA) technique in a consecutive series of 128 patients with a minimum follow-up of 24 months. A secondary aim was to compare larger preserved ACL remnants with smaller preserved remnants. METHODS: Patients who underwent primary anatomic ACL reconstruction using the SAMBBA technique from July 2013 to October 2014 were analyzed...
November 30, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29187569/dynamics-of%C3%A2-lotus-japonicus%C3%A2-ethylene-production-in-response-to-compatible-nod-factor
#4
Dugald Elgin Reid, Huijun Liu, Simon Kelly, Yasuyuki Kawaharada, Terry Mun, Stig U Andersen, Guilhem J Desbrosses, Jens Stougaard
Establishment of symbiotic nitrogen-fixation in legumes is regulated by the plant hormone ethylene, but it has remained unclear whether and how its biosynthesis is regulated by the symbiotic pathway. We established a sensitive ethylene detection system for Lotus japonicus and found that ethylene production increased as early as six hours after inoculation with Mesorhizobium loti. This ethylene response was dependent on Nod factor production by compatible rhizobia. Analyses of nodulation mutants showed that perception of Nod factor was required for ethylene emission, while downstream transcription factors including CYCLOPS, NIN and ERN1 were not required for this response...
November 29, 2017: Plant Physiology
https://www.readbyqxmd.com/read/29177328/synthesis-of-cyclopent-2-enones-from-furans-using-a-nebulizer-based-continuous-flow-photoreactor
#5
Georgios I Ioannou, Tamsyn Montagnon, Dimitris Kalaitzakis, Spiros A Pergantis, Georgios Vassilikogiannakis
A series of hydroxycyclopent-2-enones and methoxycyclopent-2-enones have been synthesized in a single operation from simple furan substrates using an innovative continuous flow nebulizer system (NebPhotOX). Photooxygenation of the furan substrates takes place in an aerosol within the NebPhotOX system.
November 27, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/29158707/a-novel-monocyclic-triterpenoid-and-a-norsesquaterpenol-from-the-aerial-parts-of-suaeda-monoica-forssk-ex-j-f-gmel-with-cell-proliferative-potential
#6
Mansour S Al-Said, Nasir A Siddiqui, Mohamed Ahmed Mukhair, Mohammad K Parvez, Perwez Alam, Mohd Ali, Anzarul Haque
Suaeda monoica Forssk. ex J.F. Gmel (Chenopodiaceae), a mangrove herb, is distributed in tropical Africa, Arabian Peninsula, India, Pakistan, Palestine and Jordan. The plant parts are used to treat sore throat, hepatitis, wounds, rheumatism, paralysis, asthma, snakebites, skin disease and ulcer. Two new phytoconstituents characterized as 13,17-octahydropentalene-4,4,10,23-tetramethyl-17,21-diisopropyl-tetradecahydrocyclo-[a]-phenanthrene-(14), 20(23), 21(30)-trien-5α-ol (SMC-3) and [1,4,4-trimethyl-cyclopent-1(5)-enyl]-9,10,17,21-tetramethyl-9α-ol-16α (17α)-epoxy heptadecan-6,10-dione (SMC-4) belong to the class norsesquaterpenol and monocyclic triterpenoid, respectively, along with two known compounds 3-epi-lupeol (SMC-1) and 4-cyclopentylpyrocatechol (SMC-2) have been isolated from the ethanol extract of aerial parts of S...
November 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/29140250/gdf3-is-required-for-robust-nodal-signaling-during-germ-layer-formation-and-left-right-patterning
#7
Jose L Pelliccia, Granton A Jindal, Rebecca D Burdine
Vertebrate embryonic patterning depends on signaling from Nodal, a TGFβ superfamily member. There are three Nodal orthologs in zebrafish; southpaw directs left-right asymmetries, while squint and cyclops function earlier to pattern mesendoderm. TGFβ member Vg1 is implicated in mesoderm formation but the role of the zebrafish ortholog, Growth differentiation factor 3 (Gdf3), has not been fully explored. We show that zygotic expression of gdf3 is dispensable for embryonic development, while maternally deposited gdf3 is required for mesendoderm formation and dorsal-ventral patterning...
November 15, 2017: ELife
https://www.readbyqxmd.com/read/29110480/lewis-acid-triggered-vinylcyclopropane-cyclopentene-rearrangement
#8
Olga A Ivanova, Alexey O Chagarovskiy, Alexey N Shumsky, Vasiliy D Krasnobrov, Irina I Levina, Igor V Trushkov
We report a mild Lewis acid-induced isomerization of donor-acceptor cyclopropanes, containing an alkenyl moiety and diverse electron-withdrawing group(s) at the adjacent positions, into substituted cyclopentenes. We have found that 1,1,2-trisubstituted cyclopent-3-enes were exclusively obtained in yield of 51 to 99% when cyclopropanes with 2-substituted alkenyl group as a donor underwent isomerization. For cyclopropanes bearing trisubstituted alkenyl group either the corresponding cyclopent-3-enes or isomeric cyclopent-2-enes having two acceptor groups at the C(1) atom were formed, with the reaction selectivity being determined by the applied Lewis acid...
November 7, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29061823/synthesis-of-2-substituted-benzothiazole-derivatives-and-their-in-vitro-anticancer-effects-and-antioxidant-activities-against-pancreatic-cancer-cells
#9
Nuray Uremis, Muhammed Mehdi Uremis, Fatma Inanc Tolun, Mustafa Ceylan, Adem Doganer, Akif Hakan Kurt
Pancreatic cancer is one of the deadliest malignancies characterized by strong resistance to almost all chemotherapeutic agents and radiotherapy. In this study, we aimed to investigate the anticancer effect, enzymatic antioxidant activity [superoxide dismutase (SOD), glutathione peroxidase (GPx)] and total antioxidant capacity (TAC) of synthesized benzothiazole compounds against adenocarcinoma cancer cells (PANC-1). 2-((1S,2S)-2-((E)-4-nitrostyryl)cyclopent-3-en-1-yl)benzo[d]thiazole and 2-((1S,2S)-2-((E)-4-fluorostyryl) cyclopent-3-en-1-yl)benzo[d]thiazole containing 2-substituted benzothiazole group were synthesized in two steps...
November 2017: Anticancer Research
https://www.readbyqxmd.com/read/29059375/translational-co-regulation-of-a-ligand-and-inhibitor-by-a-conserved-rna-element
#10
Andreas Zaucker, Agnieszka Nagorska, Pooja Kumari, Nikolai Hecker, Yin Wang, Sizhou Huang, Ledean Cooper, Lavanya Sivashanmugam, Shruthi VijayKumar, Jan Brosens, Jan Gorodkin, Karuna Sampath
In many organisms, transcriptional and post-transcriptional regulation of components of pathways or processes has been reported. However, to date, there are few reports of translational co-regulation of multiple components of a developmental signaling pathway. Here, we show that an RNA element which we previously identified as a dorsal localization element (DLE) in the 3'UTR of zebrafish nodal-related1/squint (ndr1/sqt) ligand mRNA, is shared by the related ligand nodal-related2/cyclops (ndr2/cyc) and the nodal inhibitors, lefty1 (lft1) and lefty2 mRNAs...
October 20, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29032676/following-the-molecular-mechanism-of-decarbonylation-of-unsaturated-cyclic-ketones-using-bonding-evolution-theory-coupled-with-nci-analysis
#11
Ehsan Zahedi, Samaneh Shaabani, Abolfazl Shiroudi
The synergetic use of bonding evolution theory (BET) and noncovalent interaction (NCI) analysis allows to obtain new insight into the bond breaking/forming processes and electron redistribution along the reaction path to understand the molecular mechanism of a reaction and recognize regions of strong and weak electron pairing. This viewpoint has been considered for cheletropic extrusion of CO from unsaturated cyclic ketones cyclohepta-3,5-dien-1-one CHD, cyclopent-3-en-1-one CPE, and bicyclo[2.2.1]hept-2-en-7-one BCH by using hybrid functional MPWB1K in conjugation with aug-cc-pVTZ basis set...
November 1, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28945515/multiple-nodulation-genes-are-up-regulated-during-establishment-of-reniform-nematode-feeding-sites-in-soybean
#12
Nathan Wayne Redding, Paula Agudelo, Christina E Wells
The semi-endoparastic reniform nematode (Rotylenchulus reniformis) infects over 300 plant species. Females penetrate host roots and induce formation of complex, multinucleate feeding sites called syncytia. While anatomical changes associated with reniform nematode infection are well documented, little is known about their molecular basis. We grew soybean (Glycine max) in a split-root growth system, inoculated half of each root system with R. reniformis, and quantified gene expression in infected and control root tissue at four dates after inoculation...
September 15, 2017: Phytopathology
https://www.readbyqxmd.com/read/28925289/a-new-antifungal-benzoic-acid-ester-from-uvaria-narum
#13
Alka Elizabeth Varghese, Balaji Govindan, Jyothilakshmi Madhavankutty, Antony Thomas Valiyaveetil, Madhusudhanan Karadka, Sabulal Baby
Uvaria narum has been used for gastrointestinal problems, jaundice, fever and skin diseases in traditional and ethnomedical practices. Our preliminary antifungal screening of various leaf extracts of U. narum revealed very good antifungal activity for its acetone extract. Active principle of U. narum leaf acetone extract was isolated by bioactivity-guided fractionation and characterised as a new molecule, 2-E-(2″-oxo-5″-acetoxy cyclopent-3″-en-1″-ylidene) ethyl benzoate, by NMR, IR and mass spectroscopic analyses...
September 19, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28902609/knee-extension-loss-secondary-to-a-cyclops-like-gouty-tophus-a-case-report-and-literature-review
#14
Michael Doany, Nicole Lopez, Andrew Rokito
While gouty arthritis of the knee is not uncommon, associated mechanical block to extension is a rarely seen complication. This report presents a unique case of extension loss due to a single, isolated intra-articular gouty tophus. Only a few similar reports have been described in the literature involving cases that are often initially suspected to be related to inherent structural knee pathology as opposed to a systemic condition or illness.
May 2017: Bulletin of the Hospital for Joint Diseases
https://www.readbyqxmd.com/read/28862529/an-algorithmic-approach-to-rehabilitation-following-arthroscopic-surgery-for-arthrofibrosis-of-the-knee-a-case-series
#15
Brian J Eckenrode
BACKGROUND AND PURPOSE: Loss of knee range of motion (ROM) has been reported as the most common complication following anterior cruciate ligament reconstruction (ACLR). Arthrofibrosis of the knee, or specifically Cyclops syndrome, has been described as the formation of a scar tissue nodule adjacent to the tibial tunnel of the anterior cruciate ligament (ACL) graft. This lesion often results in loss of knee extension ROM, pain, and impaired function. CASE DESCRIPTIONS: Three consecutive patients were referred to physical therapy following arthroscopic knee surgery for lysis of adhesions of a Cyclops lesion from a previous ACLR...
September 1, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28818464/one-pot-synthesis-of-bioactive-cyclopentenones-from-%C3%AE-linolenic-acid-and-docosahexaenoic-acid
#16
Daniel Maynard, Sara Mareike Müller, Monika Hahmeier, Jana Löwe, Ivo Feussner, Harald Gröger, Andrea Viehhauser, Karl-Josef Dietz
Oxidation products of the poly-unsaturated fatty acids (PUFAs) arachidonic acid, α-linolenic acid and docosahexaenoic acid are bioactive in plants and animals as shown for the cyclopentenones prostaglandin 15d-PGJ2 and PGA2, cis-(+)-12-oxophytodienoic acid (12-OPDA), and 14-A-4 neuroprostane. In this study an inexpensive and simple enzymatic multi-step one-pot synthesis is presented for 12-OPDA, which is derived from α-linolenic acid, and the analogous docosahexaenoic acid (DHA)-derived cyclopentenone [(4Z,7Z,10Z)-12-[[-(1S,5S)-4-oxo-5-(2Z)-pent-2-en-1yl]-cyclopent-2-en-1yl] dodeca-4,7,10-trienoic acid, OCPD]...
August 1, 2017: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/28789611/role-of-the-gras-transcription-factor-ata-ram1-in-the-transcriptional-reprogramming-of-arbuscular-mycorrhiza-in-petunia-hybrida
#17
Mélanie K Rich, Pierre-Emmanuel Courty, Christophe Roux, Didier Reinhardt
BACKGROUND: Development of arbuscular mycorrhiza (AM) requires a fundamental reprogramming of root cells for symbiosis. This involves the induction of hundreds of genes in the host. A recently identified GRAS-type transcription factor in Petunia hybrida, ATA/RAM1, is required for the induction of host genes during AM, and for morphogenesis of the fungal endosymbiont. To better understand the role of RAM1 in symbiosis, we set out to identify all genes that depend on activation by RAM1 in mycorrhizal roots...
August 8, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28690383/molecular-docking-based-screening-of-listeriolysin-o-for-improved-inhibitors
#18
Sara Ghafari, Matin Komeilian, Mohaddese Sadat Hashemi, Sareh Oushani, Garshasb Rigi, Behnam Rashidieh, Kamran Yarahmadi, Fatemeh Khoddam
Listeriolysine-O (LLO) is a 50KDa protein responsible for Listeria monocytogenes pathogenicity. The structure of LLO (PDB ID: 4CDB) with domains D1 to D4 is known. Therefore, it is of interest to identify conserved regions among LLO variants for destabilizing oligomerization (50 mer complex) of its monomers using appropriate inhibitors. Therefore, it is of interest to identify suitable inhibitors for inhibiting LLO. Previous reports suggest the use of flavanoids like compounds for inhibiting LLO. Our interest is to identify improved compounds to destabilize LLO oligomerization...
2017: Bioinformation
https://www.readbyqxmd.com/read/28670852/chemical-composition-antioxidant-properties-%C3%AE-glucosidase-inhibitory-and-antimicrobial-activity-of-essential-oils-from-acacia-mollissima-and-acacia-cyclops-cultivated-in-tunisia
#19
Amira Jelassi, Manel Hassine, Malek Besbes Hlila, Hichem Ben Jannet
The genus Acacia is quite large and can be found in the warm subarid and arid parts, but little is known about its chemistry, especially the volatile parts. The volatile oils from fresh flowers of A. mollissima and A. cyclops (growing in Tunisia) obtained by hydrodistillation were analyzed by GC then GC/MS. Eighteen (94.7% of the total oil composition) and 23 (97.4%) compounds were identified in these oils, respectively. (E,E)-α-Farnesene (51.5%) and (E)-cinnamyl alcohol (10.7%) constituted the major compounds of the flower oil of A...
July 3, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28657903/light-induced-photoisomerization-of-a-diarylethene-molecular-switch-on-solid-surfaces
#20
Fabian Nickel, Matthias Bernien, Martin Herder, Sandro Wrzalek, Pantelis Chittas, Kai Kraffert, Lucas M Arruda, Lalminthang Kipgen, Dennis Krüger, Stefan Hecht, Wolfgang Kuch
Diarylethenes are molecular switches, the state of which can efficiently be controlled by illumination with ultraviolet or visible light. To use the change in the molecular properties when switching between the two states for a specific function, direct contact with solid surfaces is advantageous as it provides immobilization. Here we present a study of a diarylethene derivate (T-DAE, 1,2-bis(5-methyl-2-phenylthiazol-4-yl)cyclopent-1-ene) in direct contact with highly ordered graphite as well as with semimetallic Bi(1 1 1) surfaces by x-ray photoelectron spectroscopy, x-ray absorption spectroscopy and simulated spectra based on density functional theory...
September 20, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
keyword
keyword
50778
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"