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https://www.readbyqxmd.com/read/28614606/antagonism-of-trichoderma-isolates-against-leucoagaricus-gongylophorus-singer-m%C3%A3-ller
#1
Mariela Otoni do Nascimento, Renato de Almeida Sarmento, Gil Rodrigues Dos Santos, Cléia Almeida de Oliveira, Danival José de Souza
Filamentous fungi from the genus Trichoderma are commonly found in soil. They are considered facultative mycoparasites, and are antagonists of other fungi such as the cultivar of leaf-cutting ants (Leucoagaricus gongylophorus). The aim of the present study was to bioprospect Trichoderma spp. from different soils collected from Gurupi, Tocantins, Brazil, for antagonistic effects against the mutualistic fungus of leaf-cutting ants. To isolate filamentous fungi, samples were collected from six locations. Preliminarily, isolates were identified by morphological analysis as belonging to Trichoderma...
June 14, 2017: Journal of Basic Microbiology
https://www.readbyqxmd.com/read/28612429/bioprospecting-challenges-in-unusual-environments
#2
EDITORIAL
Kristie Tanner, Cristina Vilanova, Manuel Porcar
No abstract text is available yet for this article.
June 14, 2017: Microbial Biotechnology
https://www.readbyqxmd.com/read/28609211/bioprospecting-of-functional-cellulases-from-metagenome-for-second-generation-biofuel-production-a-review
#3
Rameshwar Tiwari, Lata Nain, Nikolaos E Labrou, Pratyoosh Shukla
Second generation biofuel production has been appeared as a sustainable and alternative energy option. The ultimate aim is the development of an industrially feasible and economic conversion process of lignocellulosic biomass into biofuel molecules. Since, cellulose is the most abundant biopolymer and also represented as the photosynthetically fixed form of carbon, the efficient hydrolysis of cellulose is the most important step towards the development of a sustainable biofuel production process. The enzymatic hydrolysis of cellulose by suites of hydrolytic enzymes underlines the importance of cellulase enzyme system in whole hydrolysis process...
June 13, 2017: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/28584911/bioprospecting-for-%C3%AE-lactam-resistance-genes-using-a-metagenomics-guided-strategy
#4
Chao Yang, Ying Yang, You Che, Yu Xia, Liguan Li, Wenguang Xiong, Tong Zhang
Emergence of new antibiotic resistance bacteria poses a serious threat to human health, which is largely attributed to the evolution and spread of antibiotic resistance genes (ARGs). In this work, a metagenomics-guided strategy consisting of metagenomic analysis and function validation was proposed for rapidly identifying novel ARGs from hot spots of ARG dissemination, such as wastewater treatment plants (WWTPs) and animal feces. We used an antibiotic resistance gene database to annotate 76 putative β-lactam resistance genes from the metagenomes of sludge and chicken feces...
June 5, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28571495/phytochemical-characterisation-and-bioprospection-for-antibacterial-and-antioxidant-activities-of-lippia-alba-brown-ex-britton-wilson-verbenaceae
#5
Graziela Teixeira de Oliveira, Jaqueline Maria Siqueira Ferreira, William Gustavo Lima, Lucas Ferreira Alves, Joaquim Maurício Duarte-Almeida, Luciana Alves Rodrigues Dos Santos Lima
Ethanol extract and fractions obtained from fresh and dry aerial parts of Lippia alba were examined in order to determine their phytochemical composition, antioxidant capacity and antibacterial activities. The ethanol extracts and fractions exhibited an antioxidant effect by the DPPH assay, especially samples of fresh plant. HPLC analysis of the ethyl acetate fractions identified the presence of phenolic acids and flavonoids. The ethanol extract and fractions showed activity against reference and multidrug-resistant strains of Staphylococcus aureus and Enterococcus faecalis (MIC range 2000-250 μg/mL)...
June 1, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28545664/a-phenolic-glycoside-from-flacourtia-indica-induces-heme-mediated-oxidative-stress-in-plasmodium-falciparum-and-attenuates-malaria-pathogenesis-in-mice
#6
Shiv Vardan Singh, Ashan Manhas, Suriya P Singh, Sonali Mishra, Nimisha Tiwari, Parmanand Kumar, Karuna Shanker, Kumkum Srivastava, Koneni V Sashidhara, Anirban Pal
BACKGROUND: Flacourtia indica is especially popular among the various communities of many African countries where it is being used traditionally for the treatment of malaria. In our previous report, we have identified some phenolic glycosides from the aerial parts of F. indica as promising antiplasmodial agents under in vitro conditions. PURPOSE: Antimalarial bioprospection of F. indica derived phenolic glycoside in Swiss mice (in vivo) with special emphasis on its mode of action...
July 1, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/28538688/in-silico-study-and-bioprospection-of-the-antibacterial-and-antioxidant-effects-of-flavone-and-its-hydroxylated-derivatives
#7
Camila de Albuquerque Montenegro, Gregório Fernandes Gonçalves, Abrahão Alves de Oliveira Filho, Andressa Brito Lira, Thays Thyara Mendes Cassiano, Natanael Teles Ramos de Lima, José Maria Barbosa-Filho, Margareth de Fátima Formiga Melo Diniz, Hilzeth Luna Freire Pessôa
Flavonoid compounds are widely used as natural protective species, which can act as anti-inflammatory, antioxidant, anticoagulant, antihypertensive and antitumor agents. This study set out to investigate the probable pharmacological activities, along with the antibacterial and antioxidant effects, of flavone and its hydroxy derivatives: 3-hydroxyflavone, 5-hydroxyflavone and 6-hydroxyflavone. To do so, we investigated their pharmacological characteristics, using in silico tests that indicate likelihood of activity or inactivity, with the PASS online software, and the antimicrobial potential against Gram positive and Gram negative bacteria was also analyzed, including bacteria of clinical importance...
May 24, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28528426/building-a-bio-based-industry-in-the-middle-east-through-harnessing-the-potential-of-the-red-sea-biodiversity
#8
REVIEW
Jens Nielsen, John Archer, Magbubah Essack, Vladimir B Bajic, Takashi Gojobori, Ivan Mijakovic
The incentive for developing microbial cell factories for production of fuels and chemicals comes from the ability of microbes to deliver these valuable compounds at a reduced cost and with a smaller environmental impact compared to the analogous chemical synthesis. Another crucial advantage of microbes is their great biological diversity, which offers a much larger "catalog" of molecules than the one obtainable by chemical synthesis. Adaptation to different environments is one of the important drives behind microbial diversity...
May 20, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28525726/characterization-of-an-ionic-liquid-tolerant-%C3%AE-xylosidase-from-a-marine-derived-fungal-endophyte
#9
Anindita Sengupta, Angela Zabala, Si Yu Tan, Arthur Broadstock, T S Suryanarayanan, Venkat Gopalan
Ionic liquids (ILs) are used in lignocellulosic biomass (LCB) pretreatment due to their ability to disrupt the extensive hydrogen-bonding network in cellulose and hemicellulose, and thereby decrease LCB recalcitrance to subsequent enzymatic degradation. However, this approach necessitates development of a cellulases and hemicellulases that can tolerate ~20% (w/v) IL, an amount that either co-precipitates with the sugar polymers after the initial pretreatment or is typically used in single-pot biomass deconstructions...
May 19, 2017: Biochemistry and Cell Biology, Biochimie et Biologie Cellulaire
https://www.readbyqxmd.com/read/28523076/metaproteomics-guided-selection-of-targeted-enzymes-for-bioprospecting-of-mixed-microbial-communities
#10
Jutta Speda, Bengt-Harald Jonsson, Uno Carlsson, Martin Karlsson
BACKGROUND: Hitherto, the main goal of metaproteomic analyses has been to characterize the functional role of particular microorganisms in the microbial ecology of various microbial communities. Recently, it has been suggested that metaproteomics could be used for bioprospecting microbial communities to query for the most active enzymes to improve the selection process of industrially relevant enzymes. In the present study, to reduce the complexity of metaproteomic samples for targeted bioprospecting of novel enzymes, a microbial community capable of producing cellulases was maintained on a chemically defined medium in an enzyme suppressed metabolic steady state...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28512279/antimicrobial-potential-of-plant-extracts-and-chemical-fractions-of-sideroxylon-obtusifolium-roem-schult-t-d-penn-on-oral-microorganisms
#11
Thaíse Pd Sampaio, Nathália Ao Cartaxo-Furtado, Ana Cd de Medeiros, Harley S Alves, Pedro L Rosalen, Jozinete V Pereira
AIM: The aim of this study is to evaluate the in vitro antimicrobial activity of plant extracts and chemical fractions of Sideroxylon obtusifolium T.D. Penn on Streptococcus mutans, Streptococcus oralis, Streptococcus salivarius, Streptococcus parasanguinis, and Candida albicans as well as to identify the chemical classes found in the bioactive extracts possessing better activity. MATERIALS AND METHODS: Freeze-dried hydroalcoholic extracts of the bark and leaves (LC and LF respectively) and ethanol extracts of bark and leaves (EC and EF respectively) of S...
May 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28480140/high-diversity-and-suggested-endemicity-of-culturable-actinobacteria-in-an-extremely-oligotrophic-desert-oasis
#12
Hector Fernando Arocha-Garza, Ricardo Canales-Del Castillo, Luis E Eguiarte, Valeria Souza, Susana De la Torre-Zavala
The phylum Actinobacteria constitutes one of the largest and anciently divergent phyla within the Bacteria domain. Actinobacterial diversity has been thoroughly researched in various environments due to its unique biotechnological potential. Such studies have focused mostly on soil communities, but more recently marine and extreme environments have also been explored, finding rare taxa and demonstrating dispersal limitation and biogeographic patterns for Streptomyces. To test the distribution of Actinobacteria populations on a small scale, we chose the extremely oligotrophic and biodiverse Cuatro Cienegas Basin (CCB), an endangered oasis in the Chihuahuan desert to assess the diversity and uniqueness of Actinobacteria in the Churince System with a culture-dependent approach over a period of three years, using nine selective media...
2017: PeerJ
https://www.readbyqxmd.com/read/28476677/ethnobotanical-study-of-medicinal-plants-used-by-ribeirinhos-in-the-north-araguaia-microregion-mato-grosso-brazil
#13
Reginaldo Vicente Ribeiro, Isanete Geraldini Costa Bieski, Sikiru Olaitan Balogun, Domingos Tabajara de Oliveira Martins
ETHNOPHARMACOLOGICAL IMPORTANCE: Currently, in many traditional communities, such as the riverine community in the North Araguaia microregion (Mato Grosso, Brazil), plant knowledge and use represent the main, if not the only, therapeutic resource for the maintenance of health and/or treatment of diseases. This study aimed to identify and document species of medicinal plants used by local experts from riverine communities in the North Araguaia microregion in Mato Grosso State, and to further chemical and pharmacological studies on species selected based on searches in the relevant literature...
May 2, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28468277/sampling-terrestrial-environments-for-bacterial-polyketides
#14
REVIEW
Patrick Hill, Graham W Heberlig, Christopher N Boddy
Bacterial polyketides are highly biologically active molecules that are frequently used as drugs, particularly as antibiotics and anticancer agents, thus the discovery of new polyketides is of major interest. Since the 1980s discovery of polyketides has slowed dramatically due in large part to the repeated rediscovery of known compounds. While recent scientific and technical advances have improved our ability to discover new polyketides, one key area has been under addressed, namely the distribution of polyketide-producing bacteria in the environment...
April 29, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28420137/modification-of-the-mycotoxin-deoxynivalenol-using-microorganisms-isolated-from-environmental-samples
#15
Nina M Wilson, Nicole McMaster, Dash Gantulga, Cara Soyars, Susan P McCormick, Ken Knott, Ryan S Senger, David G Schmale
The trichothecene mycotoxin deoxynivalenol (DON) is a common contaminant of wheat, barley, and maize. New strategies are needed to reduce or eliminate DON in feed and food products. Microorganisms from plant and soil samples collected in Blacksburg, VA, USA, were screened by incubation in a mineral salt media containing 100 μg/mL DON and analysis by gas chromatography mass spectrometry (GC/MS). Two mixed cultures derived from soil samples consistently decreased DON levels in assays using DON as the sole carbon source...
April 15, 2017: Toxins
https://www.readbyqxmd.com/read/28376612/marine-algicolous-endophytic-fungi-a-promising-drug-resource-of-the-era
#16
REVIEW
Manomi Sarasan, Jayesh Puthumana, Neema Job, Jeonghoon Han, Jae-Seong Lee, Rosamma Philip
Endophytic fungi have currently been acknowledged, as the most promising source of bioactive compounds for drug discovery and considerable progress has been made in exploring their diversity, species richness, and bioprospecting. Fungal endophytes from unique environmental settings offer a pool of potentially useful medicinal entities. Due to the constant stresses imposed on macroalgae by marine environment, it is believed that algae and their associated endophytic symbionts represent a good source of structurally diverse bioactive secondary metabolites...
April 5, 2017: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28376308/differential-colonization-by-bioprospected-rhizobial-bacteria-associated-to-common-bean-in-different-cropping-systems-i-i
#17
Josiele Polzin de Oliveira-Francesquini, Mariangela Hungria, Daiani Cristina Savi, Chirlei Glienke, Rodrigo Aluizio, Vanessa Kava, Lygia Vitória Galli-Terasawa
In this study, we evaluated the diversity of rhizobia isolated from root nodules on common bean (<i>Phaseolus vulgaris</i>) derived from Andean and Mesoamerican centers and grown under field and greenhouse conditions. Genetic characterization of isolates was performed by sequencing analyses of the 16S rRNA and two housekeeping genes, <i>rec</i>A and <i>gln</i>II, and by the amplification of <i>nif</i>H. Symbiotic efficiency was evaluated by examining nodulation, plant-biomass production and plant-N accumulation...
April 4, 2017: Canadian Journal of Microbiology
https://www.readbyqxmd.com/read/28367143/comparative-mrna-expression-profiles-of-riboflavin-biosynthesis-genes-in-lactobacilli-isolated-from-human-feces-and-fermented-bamboo-shoots
#18
Kiran Thakur, Sudhir K Tomar, Zhao-Jun Wei
With the aim to bioprospect potent riboflavin producing lactobacilli, the present study was carried out to evaluate the relative mRNA expression of riboflavin biosynthesis genes namely Rib 1, Rib 2, Rib 3, and Rib 4 from potent riboflavin producers obtained from our previous studies. All the four genes were successfully cloned and sequenced for further analysis by in silico procedures. As studied by non-denaturing Polyacrylamide gel electrophoresis, no difference in size of all the four genes among those of various lactobacilli was observed...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28335513/bioactive-potential-of-marine-macroalgae-from-the-central-red-sea-saudi-arabia-assessed-by-high-throughput-imaging-based-phenotypic-profiling
#19
Stephan Kremb, Constanze Müller, Philippe Schmitt-Kopplin, Christian R Voolstra
Marine algae represent an important source of novel natural products. While their bioactive potential has been studied to some extent, limited information is available on marine algae from the Red Sea. This study aimed at the broad discovery of new bioactivities from a collection of twelve macroalgal species from the Central Red Sea. We used imaging-based High-Content Screening (HCS) with a diverse spectrum of cellular markers for detailed cytological profiling of fractionated algal extracts. The cytological profiles for 3 out of 60 algal fractions clustered closely to reference inhibitors and showed strong inhibitory activities on the HIV-1 reverse transcriptase in a single-enzyme biochemical assay, validating the suggested biological target...
March 20, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28330085/bioprospecting-and-biotechnological-applications-of-fungal-laccase
#20
REVIEW
Pooja Upadhyay, Rahul Shrivastava, Pavan Kumar Agrawal
Laccase belongs to a small group of enzymes called the blue multicopper oxidases, having the potential ability of oxidation. It belongs to enzymes, which have innate properties of reactive radical production, but its utilization in many fields has been ignored because of its unavailability in the commercial field. There are diverse sources of laccase producing organisms like bacteria, fungi and plants. In fungi, laccase is present in Ascomycetes, Deuteromycetes, Basidiomycetes and is particularly abundant in many white-rot fungi that degrade lignin...
June 2016: 3 Biotech
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