Lorenzo Cohen, Suzanne C Danhauer, M Kay Garcia, Emily V Dressler, David I Rosenthal, Mark S Chambers, Andrew Cusimano, W Mark Brown, Jewel M Ochoa, Peiying Yang, Joseph S Chiang, Ora Gordon, Rhonda Crutcher, Jung K Kim, Michael P Russin, Joshua Lukenbill, Mercedes Porosnicu, Kathleen J Yost, Kathryn E Weaver, Glenn J Lesser
IMPORTANCE: Patients with head and neck cancer who undergo radiotherapy can develop chronic radiation-induced xerostomia. Prior acupuncture studies were single center and rated as having high risk of bias, making it difficult to know the benefits of acupuncture for treating radiation-induced xerostomia. OBJECTIVE: To compare true acupuncture (TA), sham acupuncture (SA), and standard oral hygiene (SOH) for treating radiation-induced xerostomia. DESIGN, SETTING, AND PARTICIPANTS: A randomized, blinded, 3-arm, placebo-controlled trial was conducted between July 29, 2013, and June 9, 2021...
May 1, 2024: JAMA Network Open