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https://www.readbyqxmd.com/read/28929726/-factors-associated-to-medical-visits-comparison-among-italians-and-immigrants-resident-in-italy
#1
Anteo Di Napoli, Monica Perez, Alessandra Rossi, Daniele Spizzichino, Laura Iannucci, Lidia Gargiulo, Daniela Panaccione, Concetta Mirisola, Alessio Petrelli
OBJECTIVES: to evaluate the role of factors potentially associated with the use of medical visits by the immigrant population living in Italy, making a comparison with the Italian population. DESIGN: cross-sectional study based on the representative sample of the population residing in Italy considered in the Survey "Health and use of health services" conducted by the Italian National Institute of Statistics (Istat) in 2013. SETTING AND PARTICIPANTS: the study was conducted on a sample of citizens aged 18-64 years (72,476 individuals) representing a population of 37,290,440 residents in Italy (33...
May 2017: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/28927764/how-to-value-patient-values-cesarean-sections-for-the-periviable-fetus-and-home-births
#2
REVIEW
Howard Minkoff, Fouad Atallah
Respect for patient autonomy involves providing sufficient information to patients to allow them to make informed decisions, and then honoring their requests unless they are unethical or futile. At times, the factors that patients consider may not be purely biologic ones but rather will include "spiritual" factors (a sense of control in a home birth). When patients balance biologic risks against spiritual gain, physicians may not be comfortable giving deference to patients' choice. In order to explicate this issue we explore two clinical scenarios: home birth, and cesarean section for a periviable fetus; and we consider futility and limits on affirmative autonomy...
September 15, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28926764/synthesis-antimicrobial-antiquorum-sensing-antitumor-and-cytotoxic-activities-of-new-series-of-cyclopenta-hepta-b-thiophene-and-fused-cyclohepta-b-thiophene-analogs
#3
Somaya A Abdel-Rahman, Nadia S El-Gohary, Eman R El-Bendary, Saadia M El-Ashry, Mona I Shaaban
New series of cyclopenta(hepta)[b]thiophene and fused cyclohepta[b]thiophene analogs were synthesized. The new analogs were assessed for antibacterial efficacy toward Escherichia coli ATCC 12435, Bacillus cereus UW 85 and Staphylococcus aureus. Compounds 5a, 6b and 12 showed eminent activity toward all selected bacterial strains compared to ampicillin. The antifungal efficacy of the same analogs was also examined toward Candida albicans and Aspergillus fumigatus 293, whereas 5a,b and 12 showed excellent efficacy toward both of the tested fungi...
September 4, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28924062/national-trends-in-pediatricians-practices-and-attitudes-about-breastfeeding-1995-to-2014
#4
Lori Feldman-Winter, Kinga Szucs, Aubri Milano, Elizabeth Gottschlich, Blake Sisk, Richard J Schanler
BACKGROUND AND OBJECTIVES: The American Academy of Pediatrics (AAP) has affirmed breastfeeding as the preferred method of infant feeding; however, there has been little systematic examination of how pediatricians' recommendations, affiliated hospitals' policies, counseling practices, and attitudes toward breastfeeding have shifted over the past 2 decades. These trends were examined from 1995 to 2014. METHODS: Data are from the Periodic Survey (PS) of Fellows, a nationally representative survey of AAP members...
September 18, 2017: Pediatrics
https://www.readbyqxmd.com/read/28923146/cannon-ball-diagnosis-and-management-in-a-flight-attendant-candidate
#5
Meryem Zerrik, Houda Echchachoui, Zakaria Iloughmane, Choukri El'mhadi, Salaheddine Elkhader, Laila Benaissa, Mohamed Chemsi
BACKGROUND: ''Cannon ball'' opacities on chest X-rays are a common manifestation of hematogenous dissemination of a malignant tumor in the lungs. They indicate an advanced stage of disease with a very grim prognosis in terms of cure and survival. In aerospace medicine, this aspect means the patient is unfit for flight duties. Nonmetastatic etiologies of pulmonary nodules are rare. We report a case of cannon ball opacities discovered fortuitously during an admission visit. CASE REPORT: A 23-yr-old flight attendant candidate came to the Aeromedical Expertise Center of the Military Hospital in Rabat for medical evaluation...
October 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28922001/reasons-probably-won-t-change-your-mind-the-role-of-reasons-in-revising-moral-decisions
#6
Matthew L Stanley, Ashley M Dougherty, Brenda W Yang, Paul Henne, Felipe De Brigard
Although many philosophers argue that making and revising moral decisions ought to be a matter of deliberating over reasons, the extent to which the consideration of reasons informs people's moral decisions and prompts them to change their decisions remains unclear. Here, after making an initial decision in 2-option moral dilemmas, participants examined reasons for only the option initially chosen (affirming reasons), reasons for only the option not initially chosen (opposing reasons), or reasons for both options...
September 18, 2017: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/28919820/prediction-models-for-the-mortality-risk-in-chronic-dialysis-patients-a-systematic-review-and-independent-external-validation-study
#7
Chava L Ramspek, Pauline Wm Voskamp, Frans J van Ittersum, Raymond T Krediet, Friedo W Dekker, Merel van Diepen
OBJECTIVE: In medicine, many more prediction models have been developed than are implemented or used in clinical practice. These models cannot be recommended for clinical use before external validity is established. Though various models to predict mortality in dialysis patients have been published, very few have been validated and none are used in routine clinical practice. The aim of the current study was to identify existing models for predicting mortality in dialysis patients through a review and subsequently to externally validate these models in the same large independent patient cohort, in order to assess and compare their predictive capacities...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28918716/the-existential-underpinnings-of-intergroup-helping-when-normative-and-defensive-motivations-collide
#8
Gilad Hirschberger, Jenna Hayes, Adi Shtrul, Tsachi Ein-Dor
Five studies examined defensive intergroup helping-when responsibility for an out-group victim's injury decreases helping, whereas lack of responsibility increases helping when death is salient. In Study 1 ( N = 350), implicit death primes increased petition signings to allow a Palestinian child to receive medical treatment in Israel, when the child was a victim of Palestinian fire. When the child was a victim of Israeli fire, however, death primes decreased petition signings. Study 2 ( N = 200) partially replicated these effects on commitment to donate blood to an injured Palestinian child...
October 2017: Personality & Social Psychology Bulletin
https://www.readbyqxmd.com/read/28917969/hysterectomy-for-the-transgendered-male-a-review-of-perioperative-considerations-and-surgical-techniques-with-description-of-a-novel-2-port-laparoscopic-approach
#9
REVIEW
Cherie Q Marfori, Catherine Z Wu, Quinton Katler, Mollie Kotzen, Parisa Samimi, Matthew T Siedhoff
Transgendered individuals can suffer a significant amount of psychological distress which can be alleviated through hormonal treatments and/or gender-affirming surgery. The World Professional Association for Transgender Health (WPATH) considers a hysterectomy and BSO medically necessary gender-affirming procedures for the interested transgendered male. Several surgical approaches have been described in the literature, the majority of which endorse a laparoscopic approach. This review will summarize the available literature on surgical techniques in addition to reporting our institutional outcomes using a novel 2-port laparoscopic approach...
September 13, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28917139/a-good-abortion-experience-a-qualitative-exploration-of-women-s-needs-and-preferences-in-clinical-care
#10
Anna L Altshuler, Alison Ojanen-Goldsmith, Paul D Blumenthal, Lori R Freedman
What do women ending their pregnancies want and need to have a good clinical abortion experience? Since birth experiences are better studied, birth stories are more readily shared and many women who have had an abortion have also given birth, we sought to compare women's needs and preferences in abortion to those in birth. We conducted semi-structured intensive interviews with women who had both experiences in the United States and analyzed their intrapartum and abortion care narratives using grounded theory, identifying needs and preferences in abortion that were distinct from birth...
September 8, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28916537/reversibility-of-the-effects-of-natalizumab-on-peripheral-immune-cell-dynamics-in-ms-patients
#11
Tatiana Plavina, Kumar Kandadi Muralidharan, Geoffrey Kuesters, Daniel Mikol, Karleyton Evans, Meena Subramanyam, Ivan Nestorov, Yi Chen, Qunming Dong, Pei-Ran Ho, Diogo Amarante, Alison Adams, Jerome De Sèze, Robert Fox, Ralf Gold, Douglas Jeffery, Ludwig Kappos, Xavier Montalban, Bianca Weinstock-Guttman, Hans-Peter Hartung, Bruce A C Cree
OBJECTIVE: To characterize the reversibility of natalizumab-mediated changes in pharmacokinetics/pharmacodynamics in patients with multiple sclerosis (MS) following therapy interruption. METHODS: Pharmacokinetic/pharmacodynamic data were collected in the Safety and Efficacy of Natalizumab in the Treatment of Multiple Sclerosis (AFFIRM) (every 12 weeks for 116 weeks) and Randomized Treatment Interruption of Natalizumab (RESTORE) (every 4 weeks for 28 weeks) studies...
September 15, 2017: Neurology
https://www.readbyqxmd.com/read/28914704/rectoneovaginal-fistula-in-a-transgender-woman-successfully-repaired-using-a-buccal-mucosa-graft
#12
Molly Abbott Elmer-DeWitt, Hadley M Wood, Tracy Hull, Cecile A Unger
BACKGROUND: Rectoneovaginal fistulae (RnVFs) are abnormal connections between the rectum and a surgically created neovagina. Although very uncommon, they confer significant morbidity in patients and may require a multidisciplinary team approach to the repair. Risk factors for RnVF include rectal injury at the time of neovaginoplasty, malignancy in the neovagina, trauma (iatrogenic or otherwise), radiation, and neovaginal revision surgery. CASE DESCRIPTION: The patient is a 64-year-old transgender woman with recurrent RnVF following penile skin inversion neovaginoplasty, which was complicated by an intraoperative rectal injury...
September 13, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28913763/a-patient-specific-three-dimensional-hemodynamic-model-of-the-circle-of-willis
#13
Hamed Rezaie, Ali Ashrafizadeh, Afsaneh Mojra
Circle of Willis (CoW) is one of the most important cerebral arteries in the human body and various attempts have been made to study the hemodynamic of blood flow in this vital part of the brain. In the present study, blood flow in a patient specific CoW is numerically modeled to predict disease-prone regions of the CoW. Medical images and computer aided design software are used to construct a realistic three-dimensional model of the CoW for this particular case. The arteries are considered as elastic conduits and the interactions between arterial walls and the blood flow are taken into account...
September 14, 2017: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/28913696/clinicopathological-risk-factors-for-distant-metastasis-in-differentiated-thyroid-carcinoma-a-meta-analysis
#14
REVIEW
Huy Gia Vuong, Uyen N P Duong, Thong Quang Pham, Hung Minh Tran, Naoki Oishi, Kunio Mochizuki, Tadao Nakazawa, Lewis Hassell, Ryohei Katoh, Tetsuo Kondo
INTRODUCTION: Distant metastasis (DM) is not a frequent event in differentiated thyroid carcinoma (DTC) but has an adverse impact on mortality of patients with DTC. In the current study, we aimed to conduct a comprehensive systematic review and meta-analysis to investigate the risk factors for DM in DTCs and for each histological subtype. METHODS: Five electronic databases were searched from inception to December 2016 for relevant articles. Pooled odd ratios and 95% confidence interval were calculated using random-effect model...
September 14, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28910308/pulmonary-hypertension-among-5-to-18-year-old-children-with-sickle-cell-anaemia-in-nigeria
#15
Ogochukwu J Sokunbi, Ekanem N Ekure, Edamisan O Temiye, Roosevelt Anyanwu, Christy A N Okoromah
BACKGROUND: Pulmonary hypertension (PHT) is a significant cause of mortality in patients with sickle cell disease (SCD). Few studies on PHT in SCD have been carried out in children. This study aimed to estimate the prevalence of PHT in children with sickle cell anaemia (SCA) and determine its clinical and laboratory correlates. METHODS: In this cross sectional study, evaluation involved obtaining bio-data, history and physical examination findings in 175 SCA subjects with haemoglobin genotype SS aged 5 to 18 years and 175 age and sex matched controls with haemoglobin genotype AA...
2017: PloS One
https://www.readbyqxmd.com/read/28905211/three-nights-leg-thermal-therapy-could-improve-sleep-quality-in-patients-with-chronic-heart-failure
#16
Hiroyuki Sawatari, Mari K Nishizaka, Mami Miyazono, Shin-Ichi Ando, Shujiro Inoue, Masao Takemoto, Takafumi Sakamoto, Daisuke Goto, Tomoo Furumoto, Shintaro Kinugawa, Nobuko Hashiguchi, Anita Rahmawati, Hiroaki Chishaki, Tomoko Ohkusa, Chie Magota, Hiroyuki Tsutsui, Akiko Chishaki
Sleep quality is often impaired in patients with chronic heart failure (HF), which may worsen their quality of life and even prognosis. Leg thermal therapy (LTT), topical leg warming, has been shown to improve endothelial function, oxidative stress, and cardiac function in patients with HF. However, its short-term influence to sleep quality has not been evaluated in HF patients. Eighteen of 23 patients with stable HF received LTT (15 min of warming at 45 °C and 30 min of insulation) at bedtime for 3 consecutive nights and 5 patients served as control...
September 13, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28905204/racial-vs-self-affirmation-as-a-protective-mechanism-against-the-effects-of-racial-exclusion-on-negative-affect-and-substance-use-vulnerability-among-black-young-adults
#17
Michelle L Stock, Frederick X Gibbons, Janine B Beekman, Kipling D Williams, Laura S Richman, Meg Gerrard
Affirming one's racial identity may help protect against the harmful effects of racial exclusion on substance use cognitions. This study examined whether racial versus self-affirmation (vs. no affirmation) buffers against the effects of racial exclusion on substance use willingness and substance use word associations in Black young adults. It also examined anger as a potential mediator of these effects. After being included, or racially excluded by White peers, participants were assigned to a writing task: self-affirmation, racial-affirmation, or describing their sleep routine (neutral)...
September 13, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28903640/it-s-all-about-the-money-for-some-consequences-of-financially-contingent-self-worth
#18
Lora E Park, Deborah E Ward, Kristin Naragon-Gainey
Financial success is an important goal, yet striving for it is often associated with negative outcomes. One reason for this paradox is that financial pressures may be tied to basing self-worth on financial success. Studies 1a to 1c developed a measure of Financial Contingency of Self-Worth (Financial CSW), and found that it predicted more financial social comparisons, financial hassles, stress, anxiety, and less autonomy. In response to a financial (vs. academic) threat, higher Financial CSW participants experienced less autonomy, perceived financial problems more negatively, and disengaged from their financial problems (Study 2)...
May 2017: Personality & Social Psychology Bulletin
https://www.readbyqxmd.com/read/28903337/targeting-the-apoptotic-mcl-1-puma-interface-with-a-dual-acting-compound
#19
Jiyuan Liu, Zhen Tian, Nan Zhou, Xueying Liu, Chenyi Liao, Beilei Lei, Jianing Li, Shengyong Zhang, Hui Chen
Despite intensive efforts in the search for small molecules with anti-cancer activity, it remains challenging to achieve both high effectiveness and safety, since many agents lack the selectivity to only act on cancer cells. The interface of two apoptotic proteins, myeloid cell leukemia-1 (Mcl-1) and p53 upregulated modulator of apoptosis (PUMA), has been recently affirmed as a target for treating cancers, as the disruption of Mcl-1-PUMA binding can reduce cancer cell survival and protect normal cells from apoptosis...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28903182/molecular-estimation-of-alteration-in-intestinal-microbial-composition-in-hashimoto-s-thyroiditis-patients
#20
Hafiz Muhammad Ishaq, Imran Shair Mohammad, Hui Guo, Muhammad Shahzad, Yin Jian Hou, Chaofeng Ma, Zahid Naseem, Xiaokang Wu, Peijie Shi, Jiru Xu
The gut microbiota has a crucial effect on human health and physiology. Hypothyroid Hashimoto's thyroiditis (HT) is an autoimmune disorder manifested with environmental and genetic factors. However, it is hypothesized that intestinal microbes might play a vital role in the pathogenesis of HT. The aim of current was to investigate and characterize the gut microbial composition of HT patients both quantitatively and qualitatively. The fecal samples from 29 HT patients and 12 healthy individuals were collected...
September 9, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
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