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https://www.readbyqxmd.com/read/29331282/development-testing-and-implementation-of-a-training-curriculum-for-nonphysician-health-workers-to-reduce-cardiovascular-disease
#1
Maheer Khan, Pablo Lamelas, Hadi Musa, Jared Paty, Tara McCready, Robby Nieuwlaat, Eleonor Ng, Patricio Lopez-Jaramillo, Jose Lopez-Lopez, Khalid Yusoff, Fadhlina A Majid, Kien Keat Ng, Len Garis, Oyere Onuma, Salim Yusuf, Jon-David Schwalm
BACKGROUND: Cardiovascular disease (CVD) is the leading cause of death worldwide. The need to address CVD is greatest in low- and middle-income countries where there is a shortage of trained health workers in CVD detection, prevention, and control. OBJECTIVES: Based on the growing evidence that many elements of chronic disease management can be shifted to nonphysician health care workers (NPHW), the HOPE-4 (Heart Outcomes Prevention and Evaluation Program) aimed to develop, test, and implement a training curriculum on CVD prevention and control in Colombia, Malaysia, and low-resource settings in Canada...
January 10, 2018: Global Heart
https://www.readbyqxmd.com/read/29331161/hormone-therapy-gender-affirmation-surgery-and-their-association-with-recent-suicidal-ideation-and-depression-symptoms-in-transgender-veterans
#2
Raymond P Tucker, Rylan J Testa, Tracy L Simpson, Jillian C Shipherd, John R Blosnich, Keren Lehavot
BACKGROUND: Access to transition-related medical interventions (TRMIs) for transgender veterans has been the subject of substantial public interest and debate. To better inform these important conversations, the current study investigated whether undergoing hormone or surgical transition intervention(s) relates to the frequency of recent suicidal ideation (SI) and symptoms of depression in transgender veterans. METHODS: This study included a cross-sectional, national sample of 206 self-identified transgender veterans...
January 14, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29331000/evaluation-of-peer-assisted-learning-in-evidence-based-medicine-course-a-pilot-study-at-university-of-glasgow
#3
Syed Hamid Habib, Muhammad Omar Malik, Sadia Fatima, Inayat Shah
BACKGROUND: Peer Assisted Learning (PAL) is a well-established approach in learning and is increasingly being utilized in the medical education system. It is a process where active help of peer group members is taken for learning. This study aimed to look at the impact of peer assisted learning on the students at the end of the session. METHODS: Sixteen Postgraduate students attending Evidence Based Medicine (EBM) course spanning over two semesters (6 months each) were recruited...
October 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29330732/touching-the-spirit-re-enchanting-the-person-in-the-body
#4
Peggy L Determeyer, Julie E Kutac
In this essay, we argue that touch constitutes a sacred connection between the patient and practitioner. When touch is avoided or overlooked, the enigmatic inner workings of the body are ignored as those aspects of the body that can be quantified and ultimately controlled are emphasized. In utilizing touch as a fundamental way of opening up space for the sacred, the practitioner affirms the humanity for both the patient and herself. Only by returning to the senses can practitioners resist the dehumanizing effects of machinery and re-enchant the health-care profession in caring for persons they have sworn to serve...
January 12, 2018: Journal of Religion and Health
https://www.readbyqxmd.com/read/29329112/master-protocols-in-lung-cancer-experience-from-lung-master-protocol
#5
Vincent K Lam, Vassiliki Papadimitrakopoulou
PURPOSE OF REVIEW: Contemporary advances in the understanding of the molecular and immunologic basis of metastatic lung cancer have firmly changed its treatment paradigm to a personalized, biomarker-driven approach. However, the majority of lung-cancer patients [especially lung squamous cell carcinoma (LUSC)] still do not have effective targeted therapeutic options. Master protocols, such as Lung-MAP, represent an innovative clinical trial approach designed to accelerate evaluation of novel biomarker-driven therapies...
January 10, 2018: Current Opinion in Oncology
https://www.readbyqxmd.com/read/29320998/the-perceptions-and-experiences-of-women-who-achieved-and-did-not-achieve-a-waterbirth
#6
Lucy Lewis, Yvonne L Hauck, Caroline Crichton, Courtney Barnes, Corrinne Poletti, Helen Overing, Louise Keyes, Brooke Thomson
BACKGROUND: There is a gap in knowledge and understanding relating to the experiences of women exposed to the opportunity of waterbirth. Our aim was to explore the perceptions and experiences of women who achieved or did not achieve their planned waterbirth. METHODS: An exploratory design using critical incident techniques was conducted between December 2015 and July 2016, in the birth centre of the tertiary public maternity hospital in Western Australia. Women were telephoned 6 weeks post birth...
January 10, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29320643/2017-american-association-of-clinical-endocrinologists-endocrine-society-update-on-transgender-medicine-case-discussions
#7
Vin Tangpricha, Sabine E Hannema, Michael S Irwig, Walter J Meyer, Joshua D Safer, Wylie C Hembree
OBJECTIVE: Increased numbers of transgender and gender-nonconforming people are presenting to physicians in the United States and abroad due to increased public recognition and acceptance and increased access to healthcare facilities. However, there are still gaps in medical knowledge among endocrinologists and other health care professionals. The purpose of these cases is to present several common clinical vignettes of transgender people presenting in an office setting that illustrate some of the key recommendations of the Endocrine Society's revised Endocrine Treatment of Gender Dysphoria/Gender Incongruent Persons guidelines, cosponsored by the American Association of Clinical Endocrinologists...
December 2017: Endocrine Practice
https://www.readbyqxmd.com/read/29320559/characterization-of-the-naive-murine-antibody-repertoire-using-unamplified-high-throughput-sequencing
#8
Trisha A Rettig, Claire Ward, Bailey A Bye, Michael J Pecaut, Stephen K Chapes
Antibody specificity and diversity are generated through the enzymatic splicing of genomic gene segments within each B cell. Antibodies are heterodimers of heavy- and light-chains encoded on separate loci. We studied the antibody repertoire from pooled, splenic tissue of unimmunized, adult female C57BL/6J mice, using high-throughput sequencing (HTS) without amplification of antibody transcripts. We recovered over 90,000 heavy-chain and over 135,000 light-chain immunoglobulin sequences. Individual V-, D-, and J-gene segment usage was uniform among the three mouse pools, particularly in highly abundant gene segments, with low frequency V-gene segments not being detected in all pools...
2018: PloS One
https://www.readbyqxmd.com/read/29319883/trait-specific-processes-of-convergence-and-conservatism-shape-ecomorphological-evolution-in-ground-dwelling-squirrels
#9
Bryan S McLean, Kristofer M Helgen, H Thomas Goodwin, Joseph A Cook
Our understanding of mechanisms operating over deep timescales to shape phenotypic diversity often hinges on linking variation in one or few trait(s) to specific evolutionary processes. When distinct processes are capable of similar phenotypic signatures, however, identifying these drivers is difficult. We explored ecomorphological evolution across a radiation of ground-dwelling squirrels whose history includes convergence and constraint, two processes that can yield similar signatures of standing phenotypic diversity...
January 10, 2018: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/29319738/the-use-of-nanoparticles-in-wound-treatment-a-systematic-review
#10
Maria Michelle Pereira Silva, Maria Isis Freire de Aguiar, Andrea Bezerra Rodrigues, Maira Di Ciero Miranda, Michell Ângelo Marques Araújo, Isaura Letícia Tavares Palmeira Rolim, Angela Maria Alves E Souza
OBJECTIVE: To analyze the effects of nanoparticle-based dressings on the wound healing process in in vitro animals and human cells based on scientific evidence. METHOD: A systematic review of the literature in LILACS, PubMed and Science Direct databases. The articles were selected and evaluated for the level of evidence by the application of STROBE. RESULTS: The sample consisted of 12 articles. The application of the products occurred in surgical wounds, burns, infected wounds and gingival ulcers in laboratory animals, as well as in vitro tests, demonstrating that among other advantages, the nanoparticle-based dressings increased the healing speed, had good antibacterial capacity and were non cytotoxic agents...
January 8, 2018: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/29319435/black-lgb-identities-and-perceptions-of-same-sex-marriage
#11
Jess Lee
The 2015 SCOTUS ruling legalizing same-sex marriage was hailed as a universal victory for the lesbian, gay, and bisexual (LGB) community, but the pervasive support mobilized to achieve this goal may mask important dissension and inequality within the community. Specifically, how race may shape or perpetuate inequalities in the LGB community through same-sex marriage has largely been absent from the discussion. Focusing on the perceived impact of same-sex marriage in respondents' lives, I investigate the relationship between black LGBs' perception of same-sex marriage legalization and their intersectional identities and community membership...
January 10, 2018: Journal of Homosexuality
https://www.readbyqxmd.com/read/29318948/a-comparative-clinical-study-of-temporomandibular-disorder-patients-in-the-otolaryngology-clinic-versus-a-rheumatology-clinic
#12
Kamal G Effat, Abeer Berty
Objective Temporomandibular disorders (TMD) may be associated with local or widespread symptoms, including pain. The aim of this study was to compare clinical features of TMD patients presenting to an otolaryngology clinic with TMD patients presenting to a rheumatology clinic. Methods The study included 107 patients in the otolaryngology setting and 103 patients in the rheumatology setting. A comparison between both groups was made regarding the clinical data. Results Patients in the otolaryngology setting featured more otological symptoms, compared with those in the rheumatology setting...
January 10, 2018: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/29317058/whole-body-periodic-acceleration-pgz-as-a-non-invasive-preconditioning-strategy-for-pediatric-cardiac-surgery
#13
Jose A Adams, Peter Pastuszko, Arkady Uryash, David Wilson, Jose R Lopez Padrino, Vinay Nadkarni, Anna Pastuszko
We hypothesized that pGz has cardio and neuroprotective effects due to upregulation of pathways which include eNOS, anti-apoptotic, and anti-inflammatory pathways. We analyze protein expression of these pathways in the brain of neonatal piglets, as well as report on the myocardial function after Deep Hypothermic Circulatory Arrest (DHCA) and pGz preconditioning. Animal data affirms both a cardio and neuroprotective role for pGz. These findings suggest that pGz can be a simple, non-invasive cardio and neuroprotective strategy preconditioning strategy in children requiring surgical intervention...
January 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29316727/cloning-and-functional-analysis-of-phosphoethanolamine-methyltransferase-promoter-from-maize-zea-mays-l
#14
Gai-Li Niu, Wei Gou, Xiang-Long Han, Cheng Qin, Li-Xin Zhang, Abd El-Fatah Abomohra, Muhammad Ashraf
Betaine, a non-toxic osmoprotectant, is believed to accumulate considerably in plants under stress conditions to maintain the osmotic pressure and promote a variety of processes involved in growth and development. Phosphoethanolamine N-methyltransferase (PEAMT), a key enzyme for betaine synthesis, is reported to be regulated by its upstream promoter. In the present investigation, by using the transgenic approach, a 1048 bp long promoter region of ZmPEAMT gene from Zea mays was cloned and functionally characterized in tobacco...
January 8, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29314429/nurses-handoff-and-patient-safety-culture-in-perinatal-care-units
#15
Mi Yu, Hyang Yuol Lee, Gwen Sherwood, Eun Man Kim
AIM AND OBJECTIVES: This study aimed to examine nursing handoff, identify causes of handoff errors, evaluate current methods of handoff, and determine the factors associated with handoff evaluation in delivery rooms and neonatal units of hospitals in South Korea. BACKGROUND: Handoff is a critical communication process in clinical settings. Less attention has been paid to the handoff practice to assure safe perinatal care in hospitals. DESIGN: This is a cross-sectional descriptive study...
January 3, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29313738/abstention-from-drug-use-and-delinquency-increasing-among-youth-in-the-united-states-2002-2014
#16
Michael G Vaughn, Erik J Nelson, Sehun Oh, Christopher P Salas-Wright, Matt DeLisi, Katie J Holzer
BACKGROUND: Trends in abstaining from substance use and delinquency among adolescent's ages 12-17 in the United States was examined. METHODS: Data was derived from the National Survey on Drug Use and Health (NSDUH) involving non-Hispanic white, African American, and Hispanic respondents (n = 98,620) and spanning the years 2002-2014. Logistic regression was used to examine significance of trend year and correlates of low-risk and high-risk behavioral groups relative to abstaining...
January 9, 2018: Substance Use & Misuse
https://www.readbyqxmd.com/read/29313190/structural-inequities-and-social-networks-impact-hormone-use-and-misuse-among-transgender-women-in-los-angeles-county
#17
Kirsty Clark, Jesse B Fletcher, Ian W Holloway, Cathy J Reback
In order to reduce gender dysphoria and combat stigma, transgender women often affirm their gender through social and medical transition, which may include cross-sex hormone therapy. This study examined associations between medically monitored hormone use and hormone misuse (non-prescribed hormone use including "fillers"), structural inequities (access to housing, health insurance, and income), and social network dynamics among 271 transgender women in Los Angeles. Hormone use status was coded trichotomously (hormone use, hormone misuse, no hormone use), and robust multinomial logistic regression as well as novel social network analysis was conducted to examine associations...
January 8, 2018: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/29306387/attitudes-and-perceptions-of-radiographers-applying-lead-pb-protection-in-general-radiography-an-ethnographic-study
#18
C M Hayre, S Blackman, K Carlton, A Eyden
INTRODUCTION: Since the discovery of X-rays by Rontgen in 1895, lead (Pb) has been used to limit ionising radiation for both operators and patients due to its high density and high atomic number (Z = 82). This study explores the attitudes and perceptions of diagnostic radiographers applying Pb protection during general radiographic examinations, an area underexplored within a contemporary radiographic environment(s). METHODS: This paper presents findings from a wider ethnographic study undertaken in the United Kingdom (UK)...
February 2018: Radiography
https://www.readbyqxmd.com/read/29306369/can-placing-lead-rubber-inferolateral-to-the-light-beam-diaphragm-limit-ionising-radiation-to-multiple-radiosensitive-organs
#19
C Hayre, H Bungay, C Jeffery, C Cobb, J Atutornu
INTRODUCTION: This article investigates a practical method of reducing the impact of scattered radiation during a lateral radiographic projection of the elbow. The light beam diaphragm (LBD) is generally accepted to limit ionising radiation using horizontal and longitudinal lead shutters, yet this article evidences further dose limitation by placing lead-rubber inferolateral to the LBD device. METHODS: Using an anthropomorphic phantom and arm construction scattered radiation was recorded at multiple radiosensitive organs...
February 2018: Radiography
https://www.readbyqxmd.com/read/29303359/bayesian-penalised-likelihood-reconstruction-q-clear-of-18f-fluciclovine-pet-for-imaging-of-recurrent-prostate-cancer-semi-quantitative-and-clinical-evaluation
#20
Eugene J Teoh, Daniel R McGowan, David M Schuster, Maria Tsakok, Fergus V Gleeson, Kevin M Bradley
OBJECTIVE: 18F-Fluciclovine (FACBC) is an amino acid PET radiotracer approved for recurrent prostate cancer imaging. We investigate the use of Bayesian penalised likelihood (BPL) reconstruction for 18F-fluciclovine PET. METHODS: Fifteen 18F-fluciclovine scans were reconstructed using OSEM, OSEM+point spread function modeling (PSF) and BPL using β values 100-600. Lesion SUVmax, organ SUVmean and standard deviation were measured. De-identified reconstructions (OSEM, PSF, BPL using β200-600) from 10 cases were visually analysed by two readers who indicated their most and least preferred reconstructions, and scored overall image quality (IQ), noise level, background marrow IQ and lesion conspicuity...
January 5, 2018: British Journal of Radiology
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