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https://www.readbyqxmd.com/read/28727818/prep-in-italy-the-time-may-be-ripe-but-who-s-paying-the-bill-a-nationwide-survey-on-physicians-attitudes-towards-using-antiretrovirals-to-prevent-hiv-infection
#1
Antonio Di Biagio, Niccolò Riccardi, Alessio Signori, Renato Maserati, Silvia Nozza, Andrea Gori, Stefano Bonora, Marco Borderi, Diego Ripamonti, Maria Cristina Rossi, Giancarlo Orofino, Tiziana Quirino, Giuseppe Nunnari, Benedetto Maurizio Celesia, Salvatore Martini, Caterina Sagnelli, Giovanni Mazzola, Pietro Colletti, Dario Bartolozzi, Teresa Bini, Nicoletta Ladisa, Filippo Castelnuovo, Annalisa Saracino, Sergio Lo Caputo
Several studies have demonstrated the efficacy of the oral pre-exposure prophylaxis (PrEP) with tenofovir (with or without emtricitabine) on preventing HIV-negative partners of HIV infected patients to become infected through sexual contacts. PrEP is already available in the United States and now is approved by European Medicine Agency. In this setting we would like to gauge physicians' knowledge, acquaintance with and attitude to include PrEP in their clinical practice. A cross sectional survey was conducted among Italian physicians expert on antiretroviral therapy...
2017: PloS One
https://www.readbyqxmd.com/read/28727508/collective-stories-of-exercise-making-sense-of-gym-experiences-with-disabled-peers
#2
Emma V Richardson, Brett Smith, Anthony Papathomas
Using a dialogical narrative approach, we explored how disabled people made sense of their gym experiences as part of a peer group. Interviews were conducted with 18 disabled people (10 men and 8 women, aged 23-60) who had experience exercising in the gym as part of a group. Data were rigorously analyzed using a dialogical narrative analysis. Within their peer group, participants crafted a collective story that they used to resist disablism in the gym. The dialogical components of the collective story functioned to (a) validate participants' experiences of oppression in the gym, (b) forge an unspoken understanding with peers, (c) craft a more affirmative identity, and (d) instill a sense of empowerment in participants so that they can tell their own story...
July 2017: Adapted Physical Activity Quarterly: APAQ
https://www.readbyqxmd.com/read/28726178/being-of-two-minds-assessing-vacillating-and-simultaneous-ambivalence-with-the-density-matrix
#3
James Camparo, Lorinda B Camparo
Ambivalence is a common experience that permeates a broad range of research. Unfortunately, quantifying ambivalence has proven a daunting task, with researchers limited to studying vacillating ambivalence, VA (i.e., temporal oscillations between favor/disfavor evaluations of an attitude object). Here, we demonstrate the use of the density matrix to measure both VA and what we term "simultaneous ambivalence" (SA): ambivalence that manifests itself as "in the moment" concurrent favor/disfavor evaluations. In a methodological study we gave participants the option of either single-responding or double-responding to questionnaire items regarding a controversial topic (i...
July 19, 2017: Behavior Research Methods
https://www.readbyqxmd.com/read/28725144/comparative-study-of-antioxidant-activity-and-validated-rp-hptlc-analysis-of-rutin-in-the-leaves-of-different-acacia-species-grown-in-saudi-arabia
#4
Perwez Alam, Mohamed F Alajmi, Ahmed H Arbab, Mohammad K Parvez, Nasir A Siddiqui, Saleh I Alqasoumi, Adnan J Al-Rehaily, Mohammed S Al-Dosari, Omer A Basudan
The present study assessed the comparative antioxidant potential of the ethanol extract (EE) of leaves of four Acacia species (Acacia salicina, AS; Acacia laeta, AL; Acacia hamulosa AH; and Acacia tortilis, AT) grown in Saudi Arabia, including RP-HPTLC quantification of antioxidant biomarker rutin. In vitro DPPH radical scavenging and β-carotene-linoleic acid bleaching assays showed the promising antioxidant activities of Acacia extracts: ASEE (IC50: 60.39 and 324.65 μg/ml) >ALEE (IC50: 217.06 and 423...
July 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28724429/the-noncoding-rna-hoxd-as1-is-a-critical-regulator-of-the-metastasis-and-apoptosis-phenotype-in-human-hepatocellular-carcinoma
#5
Shan Lu, Jiansheng Zhou, Yimin Sun, Nan Li, Mingyong Miao, Binghua Jiao, Huan Chen
BACKGROUND: Despite accumulating evidence that long noncoding RNAs (lncRNAs) are associated with cancer development in multiple types of cancer, the biological roles of many lncRNAs in human hepatocellular carcinoma (HCC) metastasis have not been well characterized. METHODS: A lncRNA+ mRNA human gene expression microarray analysis was used to identify differentially expressed lncRNAs in metastatic HCC tissues compared to non-metastatic tissue. RESULTS: We observed remarkable overexpression of HOXD-AS1 in metastatic cancer tissues...
July 19, 2017: Molecular Cancer
https://www.readbyqxmd.com/read/28724009/the-dialog-between-health-and-foreign-policy-in-brazilian-cooperation-in-human-milk-banks
#6
Tiago Mocellin Pittas, Clarissa Franzoi Dri
Mother's milk is the primary source of nourishment in early infancy. When this source is unavailable, secondary sources may be used, such as human milk banks. The first milk bank in Brazil was created in 1943, and they have been used ever since. A national model was developed through a number of phases, culminating in the Brazilian Network of Human Milk Banks. This gave rise to a number of international cooperation projects, with the Brazilian model particularly relevant for developing nations. The main objective of this analysis is to understand what drives Brazil to promote milk banks internationally...
July 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28723670/quaking-5-suppresses-aggressiveness-of-lung-cancer-cells-through-inhibiting-%C3%AE-catenin-signaling-pathway
#7
Xuexia Zhou, Xuebing Li, Cuiyun Sun, Cuijuan Shi, Dan Hua, Lin Yu, Yanjun Wen, Feng Hua, Qian Wang, Qinghua Zhou, Shizhu Yu
Quaking-5 (QKI-5) belongs to the STAR (signal transduction and activation of RNA) family of RNA binding proteins and functions as a tumor suppressor in several human malignancies. In this study, we attempt to elucidate the role of QKI-5 in the pro-metastasis processes of lung cancer (LC) cells and the underlying mechanisms. We confirmed that QKI-5 was decreased in human LC tissues and cell lines, especially in high-metastatic cells. Moreover, QKI expression was positively correlated with LC patients' survival...
July 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/28723604/possible-joint-involvement-of-the-cochlea-and-semicircular-canals-in-the-perception-of-low-frequency-tinnitus-also-called-the-hum-or-taos-hum
#8
Franz Gunter Frosch
INTRODUCTION: "The hum" or "Taos hum" are common terms of a tinnitus with three remarkable features. OBJECTIVE: A possible common background is reevaluated for the three features of the hum: being sensitive on sound, head rotation, and long-distance air travel. MATERIALS AND METHODS: Questionnaires that were originally developed by Frosch were recalculated concerning the question of hum interactions with sounds. The question was split into the two affirmative answers a) "masking", which corresponds to the overrule of the hum by a sound, and b) "beats", which correspond to a nonlinear interaction with the hum as a Van der Pol-like oscillator...
June 1, 2017: International Tinnitus Journal
https://www.readbyqxmd.com/read/28721815/conjunctival-icterus-an-important-but-neglected-sign-of-clinically-relevant-hyperbilirubinemia-in-jaundiced-neonates
#9
Jon Freeman Watchko, Abeer Azzuqa
BACKGROUND: Conjunctival icterus is a largely neglected physical sign that may be helpful in identifying neonates with clinically relevant hyperbilirubinemia by practitioners in the hospital and outpatient clinic or parents at home. OBJECTIVE: A recent NICU based study reported that conjunctival icterus is often a sign of significant (TSB ≥ 17 mg/dl) hyperbilirubinemia and TSB levels ≥ 76th-95th percentile on the Bhutani nomogram. In contrast, others report that conjunctival icterus, although frequently present at high TSB levels, may also be detected at lower TSB concentrations; suggesting instead that its absence may help to rule out significant hyperbilirubinemia...
July 18, 2017: Current Pediatric Reviews
https://www.readbyqxmd.com/read/28721501/examining-transgender-health-through-the-international-classification-of-functioning-disability-and-health-s-icf-contextual-factors
#10
REVIEW
Melissa Jacob, Steven R Cox
PURPOSE: For many transgender individuals, medical intervention is necessary to live as their desired gender. However, little is known about Contextual Factors (i.e., Environmental and Personal) that may act as facilitators and barriers in the health of transgender individuals. Therefore, this paper sought to examine Contextual Factors of the World Health Organization's International Classification of Functioning, Disability, and Health that may facilitate or negatively impact the physical, psychological, and social functioning of transgender individuals...
July 18, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28719979/prevalence-of-protective-shielding-utilization-for-radiation-dose-reduction-in-adult-patients-undergoing-body-scanning-using-computed-tomography
#11
Shoaib Safiullah, Roshan M Patel, Brittany Uribe, Kyle Spradling, Chandana Lall, Lishi Zhang, Zhamshid Okhunov, Ralph Clayman, Jaime Landman
PURPOSE: Ionizing radiation is implicated in nearly 2% of malignancies in the United States; radiation shields prevent unnecessary radiation exposure during medical imaging. Contemporary radiation shield utilization for adult patients in the United States is poorly defined. Therefore, we evaluated the prevalence of protective shielding utilization in adult patients undergoing computed tomography scans in United States' hospitals. METHODS: An online survey was sent to established radiology departments randomly selected from the 2015 American Hospital Association Guide...
July 18, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28718874/everyday-territories-homelessness-outreach-work-and-city-space
#12
Robin James Smith, Tom Hall
This article develops a situational approach to understanding urban public life and, in particular, the production of urban territories. Our aim is to examine the ways in which city space might be understood as comprising multiple, shifting, mobile and rhythmed territories. We argue that such territories are best understood through attending to their everyday production and negotiation, rather than handling territory as an a priori construct. We develop this argument from the particular case of the street-level politics of homelessness and street care...
July 18, 2017: British Journal of Sociology
https://www.readbyqxmd.com/read/28717713/breaking-cancer-bad-news-to-patients-with-cancer-a-comprehensive-perspective-of-patients-their-relatives-and-the-public-example-from-a-middle-eastern-country
#13
Jamal Zekri, Syed Mustafa Karim
PURPOSE: Empowering patients with cancer requires that they be continuously informed about their condition. In some Eastern cultures, this concept is often opposed by caregivers. We aim to compare the extent of disclosure desired by actual and presumed patients with cancer and their relatives in our practice. METHODS: Nine questions reflecting possible bad news communication to patients from diagnosis to the end of life were designed to investigate the extent of desired disclosure and were answered by 100 patients (cohort I) and 103 accompanying relatives (cohort II) in an outpatient setting...
October 2016: Journal of Global Oncology
https://www.readbyqxmd.com/read/28714708/ethnic-identity-in-context-of-ethnic-discrimination-when-does-gender-and-other-group-orientation-increase-risk-for-depressive-symptoms-for-immigrant-origin-young-adults
#14
M Alexander Thibeault, Gabriela L Stein, Rosemery O Nelson-Gray
OBJECTIVES: Ethnic discrimination increases risk for depressive symptoms, but less is known about factors that influence the impact of this cultural challenge on psychological adjustment for immigrant-origin college students. Sociocultural identity development is especially relevant during emerging adulthood. Studies examining exacerbating or buffering impacts of ethnic identity have yielded mixed results. The current study examines conditions under which one aspect of ethnic identity, affirmation/belonging, moderates the impact of perceived ethnic discrimination stress on depressive symptoms...
July 17, 2017: Cultural Diversity & Ethnic Minority Psychology
https://www.readbyqxmd.com/read/28712419/the-relationship-between-childhood-adversities-and-fibromyalgia-in-the-general-population
#15
Aleksi Varinen, Elise Kosunen, Kari Mattila, Tuomas Koskela, Markku Sumanen
BACKGROUND: Fibromyalgia is a syndrome characterized by widespread pain and a variety of somatic symptoms. The international prevalence of fibromyalgia is 2-5%, but its current prevalence in Finland is unclear. Various adversities are linked to the onset of fibromyalgia. However, there is need for more data regarding the association between childhood physical abuse and fibromyalgia. Further, the association of childhood emotional stressors and fibromyalgia is disputed. The aim of the current study is to produce more information about that relationship using data from the Health and Social Support (HeSSup) Study...
August 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28710060/values-affirmation-intervention-reduces-achievement-gap-between-underrepresented-minority-and-white-students-in-introductory-biology-classes
#16
Hannah Jordt, Sarah L Eddy, Riley Brazil, Ignatius Lau, Chelsea Mann, Sara E Brownell, Katherine King, Scott Freeman
Achievement gaps between underrepresented minority (URM) students and their white peers in college science, technology, engineering, and mathematics classrooms are persistent across many white-majority institutions of higher education. Attempts to reduce this phenomenon of underperformance through increasing classroom structure via active learning have been partially successful. In this study, we address the hypothesis that the achievement gap between white and URM students in an undergraduate biology course has a psychological and emotional component arising from stereotype threat...
2017: CBE Life Sciences Education
https://www.readbyqxmd.com/read/28708447/coverage-for-gender-affirming-care-making-health-insurance-work-for-transgender-americans
#17
William V Padula, Kellan Baker
Many transgender Americans continue to remain uninsured or are underinsured because of payers' refusal to cover medically necessary, gender-affirming healthcare services-such as hormone therapy, mental health counseling, and reconstructive surgeries. Coverage refusal results in higher costs and poor health outcomes among transgender people who cannot access gender-affirming care. Research into the value of health insurance coverage for gender-affirming care for transgender individuals shows that the health benefits far outweigh the costs of insuring transition procedures...
July 14, 2017: LGBT Health
https://www.readbyqxmd.com/read/28705365/gender-quotas-for-women-in-national-politics-a-comparative-analysis-across-development-thresholds
#18
Jennifer Rosen
Women's share of global lower or single house parliamentary seats has increased by over 70% over the course of the 21st century. Yet these increases have not been uniform across countries. Rather countries with low levels of socioeconomic development have outpaced developed democracies in terms of the gains made in the formal political representation of women. One reasonable explanation for this trend is the adoption in many poorer countries of national gender quota legislation, that is, affirmative action laws intended to compensate for sex discrimination in the electoral process...
August 2017: Social Science Research
https://www.readbyqxmd.com/read/28704520/a-self-affirmation-exercise-does-not-improve-intentions-to-vaccinate-among-parents-with-negative-vaccine-attitudes-and-may-decrease-intentions-to-vaccinate
#19
Rachael D Reavis, Jacob B Ebbs, Adaobi K Onunkwo, L Mariah Sage
Two studies investigated the effectiveness of a self-affirmation exercise on vaccine safety beliefs and intent to vaccinate future children. In Study 1, a sample of 585 parents with at least one child under the age of 18 in the home participated through Amazon's MTurk. Participants were randomly assigned to one of four conditions in a 2 x 2 design. Participants read either correcting information refuting a link between the measles, mumps, and rubella (MMR) vaccine and autism or a control passage about bird feeding...
2017: PloS One
https://www.readbyqxmd.com/read/28704458/-the-care-is-the-best-you-can-give-at-the-time-health-care-professionals-experiences-in-providing-gender-affirming-care-in-south-africa
#20
Sarah Spencer, Talia Meer, Alex Müller
BACKGROUND: While the provision of gender affirming care for transgender people in South Africa is considered legal, ethical, and medically sound, and is-theoretically-available in both the South African private and public health sectors, access remains severely limited and unequal within the country. As there are no national policies or guidelines, little is known about how individual health care professionals providing gender affirming care make clinical decisions about eligibility and treatment options...
2017: PloS One
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