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https://www.readbyqxmd.com/read/29160964/examining-depression-in-patients-on-dialysis
#1
Allison A Treadwell
This study measured the prevalence of depression in 39 patients on hemodialysis and peritoneal dialysis in two urban outpatient facilities in the southeastern United States. Additionally, it evaluated the number of patients who sought and scheduled a mental health evaluation after screening and education. The prevalence of mild to severely depressed individuals among participants in this study was 36%, affirming previous findings of depressive symptoms in the ESRD population. Results suggest that patients with ESRD are at a higher risk for depression than the general population...
July 2017: Nephrology Nursing Journal: Journal of the American Nephrology Nurses' Association
https://www.readbyqxmd.com/read/29160462/access-to-medicines-relations-with-the-institutionalization-of-pharmaceutical-services
#2
Rafael Damasceno de Barros, Ediná Alves Costa, Djanilson Barbosa Dos Santos, Gisélia Santana Souza, Juliana Álvares, Augusto Afonso Guerra, Francisco de Assis Acurcio, Ione Aquemi Guibu, Karen Sarmento Costa, Margô Gomes de Oliveira Karnikowski, Orlando Mario Soeiro, Silvana Nair Leite
OBJETIVE: To analyze the relationship between access to medicines by the population and the institutionalization of pharmaceutical services in Brazilian primary health care. METHODS: This study is part of the Pesquisa Nacional sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos - Serviços 2015 (PNAUM - National Survey on Access, Use and Promotion of Rational Use of Medicines - Services 2015), a cross-sectional, exploratory, and evaluative study composed of an information survey in a representative sample of cities, stratified by Brazilian regions...
November 13, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29159310/factors-associated-with-gender-affirming-surgery-and-age-of-hormone-therapy-initiation-among-transgender-adults
#3
Noor Beckwith, Sari L Reisner, Shayne Zaslow, Kenneth H Mayer, Alex S Keuroghlian
Purpose: Gender-affirming surgeries and hormone therapy are medically necessary treatments to alleviate gender dysphoria; however, significant gaps exist in the research and clinical literature on surgery utilization and age of hormone therapy initiation among transgender adults. Methods: We conducted a retrospective review of electronic health record data from a random sample of 201 transgender patients of ages 18-64 years who presented for primary care between July 1, 2010 and June 30, 2015 (inclusive) at an urban community health center in Boston, MA...
2017: Transgender Health
https://www.readbyqxmd.com/read/29158769/physicians-duty-to-recontact-and-update-genetic-advice
#4
Yvonne A Stevens, Grant D Senner, Gary E Marchant
This perspective addresses whether physicians have a duty to recontact former or current patients to update clinical advice based on newly discovered genomic information. Genetic information is unique compared with other medical data in that the underlying data do not appreciably change during the patients' lifetime, but the clinical significance of that information will continue to evolve. Based on relevant case law and guidelines, there is no general, established legal duty for physicians to affirmatively recontact former or current patients to update clinical advice based on newly discovered genetic information...
2017: Personalized Medicine
https://www.readbyqxmd.com/read/29157902/interaction-of-catecholamine-precursor-l-dopa-with-lysozyme-a-biophysical-insight
#5
Saima Nusrat, Aiman Masroor, Masihuz Zaman, Mohd Khursheed Siddiqi, Mohammad Rehan Ajmal, Nida Zaidi, Ali Saber Abdelhameed, Rizwan Hasan Khan
The current study comprises of an inclusive biophysical study, enlightening the binding of L-3, 4-dihydroxyphenylalanine (L-Dopa) with human lysozyme (HL) and hen egg white lysozyme (HEWL). Spectroscopic and molecular docking tools have been utilized to study the interaction of L-Dopa with both HL and HEWL. Spectrofluorimetric measurements exhibited that L-Dopa quenched the HL and HEWL intrinsic fluorescence. A binding constant (Kb) of ∼10(4)M(-1) for both HL and HEWL was obtained, asserting a significant binding...
November 17, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29156233/trans-cervical-resection-of-a-separate-substernal-goitre
#6
Henry To, Antara Karmakar, Stephen Farrell, Steve Manolas
INTRODUCTION: A separate substernal goitre which is not continuous with the main cervical thyroid proves a unique challenge for resection. A trans-cervical approach is preferred but may be hazardous due to the possibility of ectopic thyroid tissue with alternate blood supply. PRESENTATION OF CASE: A 72year old female who had a previous left hemithyroidectomy presents with a symptomatic central substernal thyroid mass. Following radiological work-up, the separate goitre was carefully removed via a trans-cervical approach and avoidance of sternotomy...
November 10, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29154610/identity-concealment-in-transgender-adults-a-qualitative-assessment-of-minority-stress-and-gender-affirmation
#7
Brian A Rood, Meredith R Maroney, Jae A Puckett, Ariel K Berman, Sari L Reisner, David W Pantalone
Minority individuals might conceal their identity in social contexts in an effort to avoid stigma and victimization. Unfortunately, identity concealment is thought to impact psychological distress in transgender and gender nonconforming (TGNC) individuals. Thus, through 30 in-depth interviews, we sought to understand if and how identity concealment was experienced by TGNC individuals. Findings indicated that (a) TGNC identity concealment is a source of stress, (b) individuals might conceal their TGNC identity based on social context, (c) concealment of assigned sex and gender history can function to affirm one's true gender identity, and (d) concealment of gender history is a rejection of one's assigned sex...
2017: American Journal of Orthopsychiatry
https://www.readbyqxmd.com/read/29153849/cutting-balloon-and-high-pressure-balloon-dilation-for-palliative-treatment-of-congenital-double-chambered-right-ventricle-and-primary-infundibular-stenosis-in-a-golden-retriever-dog
#8
Karsten E Schober, Jaylyn Rhinehart, Rebecca Kohnken, John D Bonagura
Combined cutting balloon and high-pressure balloon dilation was performed in a dog with a double-chambered right ventricle and severe infundibular stenosis of the right ventricular outflow tract. The peak systolic pressure gradient across the stenosis decreased by 65% after dilation (from 187 mmHg before to 66 mmHg after) affirming the intervention as successful. However, early re-stenosis occurred within 3 months leading to exercise intolerance, exercise-induced syncope, and right-sided congestive heart failure...
November 16, 2017: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/29153536/frailty-in-hospitalized-older-adults-comparing-different-frailty-measures-in-predicting-short-and-long-term-patient-outcomes
#9
Edward Chong, Esther Ho, Jewel Baldevarona-Llego, Mark Chan, Lynn Wu, Laura Tay, Yew Yoong Ding, Wee Shiong Lim
OBJECTIVES: Data for the assessment of frailty in acutely ill hospitalized older adults remains limited. Using the Frailty Index (FI) as "gold standard," we compared (1) the diagnostic performance of 3 frailty measures (FRAIL, Clinical Frailty Scale [CFS], and Tilburg Frailty Indicator [TFI]) in identifying frailty, and (2) their ability to predict negative outcomes at 12 months after enrollment. DESIGN: Prospective cohort study. PARTICIPANTS: We recruited 210 patients (mean age 89...
November 15, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29151825/a-network-of-helping-generalized-reciprocity-and-cooperative-behavior-in-response-to-peer-and-staff-affirmations-and-corrections-among-therapeutic-community-residents
#10
Nathan J Doogan, Keith Warren
Background: Clinical theory in therapeutic communities (TCs) for substance abuse treatment emphasizes the importance of peer interactions in bringing about change. This implies that residents will respond in a more prosocial manner to peer versus staff intervention and that residents will interact in such a way as to maintain cooperation. Method: The data consist of electronic records of peer and staff affirmations and corrections at four corrections-based therapeutic community units...
2017: Addiction Research & Theory
https://www.readbyqxmd.com/read/29149520/compassion-in-practice-evaluating-the-awareness-involvement-and-perceived-impact-of-a-national-nursing-and-midwifery-strategy-amongst-health-care-professionals-in-nhs-trusts-in-england
#11
Helen Allan, Mike O'Driscoll, Liang Liu, Kevin Corbett, Laura Serrant
AIM: To report the findings from an evaluation of the impact of the Compassion in Practice Vision & Strategy (CiPVS) (National Health Service England (NHSE), 2012) on nursing, midwifery and care staff. BACKGROUND: The CiPVS was a programme of work to highlight the importance of compassionate care following the Francis Report in 2013 into the deficits in care in an NHS hospital trust. It was launched by NHS England in 2012 at a time when fiscal cuts were introduced by the Department of Health in England...
November 17, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29148337/hospital-compare-and-hospital-choice-public-reporting-and-hospital-choice-by-hip-replacement-patients-in-texas
#12
Robert S Blake, Harold D Clarke
The Centers for Medicare & Medicaid Services publicizes comparative performance data on Hospital Compare, a website maintained to support consumer decision making. Given the agency's goal, this study investigates the relationship between public reporting and hospital choices of hip replacement patients in Texas. Estimating individual-level valuations of provider characteristics allowing for heterogeneity across patients, we find consumer selections and hospitals' displayed performance vary together in time...
March 1, 2017: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/29143629/from-erasure-to-opportunity-a-qualitative-study-of-the-experiences-of-transgender-men-around-pregnancy-and-recommendations-for-providers
#13
Alexis Hoffkling, Juno Obedin-Maliver, Jae Sevelius
BACKGROUND: Some transgender men retain their uterus, get pregnant, and give birth. However, societal attitudes about gender have erected barriers to openly being pregnant and giving birth as a transgender man. Little research exists regarding transgender men's reproductive needs. Anecdotal observations suggest that social change and increasing empowerment of transgender men may result in increasing frequency and openness about pregnancy and birth. Specific needs around conception, pregnancy, and newborn care may arise from transphobia, exogenous testosterone exposure, or from having had (or desiring) gender-affirming surgery...
November 8, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29142421/extract-of-bauhinia-vahlii-shows-antihyperglycemic-activity-reverses-oxidative-stress-and-protects-against-liver-damage-in-streptozotocin-induced-diabetic-rats
#14
Ahmed H Elbanna, Mohammed M Nooh, Engy A Mahrous, Amal E Khaleel, Taha S Elalfy
Background: Several studies have affirmed the effectiveness of some Bauhinia plants as antihyperglycemic agents. Objective: We investigated the possible effect of Bauhinia vahlii leaves extract in reducing hyperglycemia and reversing signs of organ damage associated with diabetes in streptozotocin (STZ) rat model. Materials and Methods: Both polar fraction of the B. vahlii leaves (defatted ethanolic extract [DEE]) and nonpolar fraction (n-hexane extract) were evaluated in vitro for α-glucosidase inhibition and 2,2-diphenyl-1-picrylhydrazyl radical scavenging potential...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29140778/visual-communication-and-cognition-in-everyday-decision-making
#15
Claudine Jaenichen
Understanding cognition and the context of decision-making should be prioritized in the design process in order to accurately anticipate the outcome for intended audiences. A thorough understanding of cognition has been excluded from being a part of foundational design principals in visual communication. By defining leisure, direct, urgent, and emergency scenarios and providing examples of work that deeply considers the viewer's relationship to the design solution in context of these scenarios allows us to affirm the relevancy of cognition as a design variable and the importance of projects that advocate public utility...
November 2017: IEEE Computer Graphics and Applications
https://www.readbyqxmd.com/read/29140557/withdrawn-pharmacological-cardioversion-for-atrial-fibrillation-and-flutter
#16
REVIEW
John Cordina, Gillian E Mead
BACKGROUND: Atrial fibrillation is the commonest cardiac dysrhythmia. It is associated with significant morbidity and mortality. There are two approaches to the management of atrial fibrillation: controlling the ventricular rate or converting to sinus rhythm in the expectation that this would abolish its adverse effects. OBJECTIVES: To assess the effects of pharmacological cardioversion of atrial fibrillation in adults on the annual risk of stroke, peripheral embolism, and mortality...
November 15, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29138982/characterizing-the-hiv-prevention-and-care-continua-in-a-sample-of-transgender-youth-in-the-u-s
#17
Sari L Reisner, Laura Jadwin-Cakmak, Jaclyn M White Hughto, Miguel Martinez, Liz Salomon, Gary W Harper
In the U.S., transgender and other gender minority (TG) youth are an at-risk group understudied in HIV prevention and treatment. This study sought to characterize the HIV prevention and care continua in a diverse sample of 181 sexually-active TG ages 16-24 years (mean age = 20.7 years; 76.8% trans feminine; 69.1% youth of color) recruited July-December 2015 in 14 U.S. cities. Overall, 30.9% reported living with HIV, of which 71.4% were on antiretroviral therapy (ART) and 55.0% were medication adherent; 65...
November 14, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/29138569/post-marketing-observational-program-of-the-effectiveness-of-fluvoxamine-for-the-treatment-of-depression-in-patients-with-neurological-disorders-the-friends-study
#18
Nikolay N Yahno, Anastasia V Fedotova
In a prospective, non-blinded, uncontrolled, multicenter, post-marketing, observational study (FRIENDS; NCT02043197), fluvoxamine (50-300 mg/day for 90 days) was effective for the treatment of depression in 299 adult patients (age ≥18 years) with neurological disorders at baseline. The therapeutic effect of fluvoxamine was measured by means of changes in the Hospital Anxiety and Depression Scale depression and anxiety scores (HADS-D and HADS-A, respectively), global severity of illness, and clinical condition (measured using the Clinical Global Improvement [CGI] scale)...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29137254/quaking-5-suppresses-aggressiveness-of-lung-cancer-cells-through-inhibiting-%C3%AE-catenin-signaling-pathway
#19
Xuexia Zhou, Xuebing Li, Cuiyun Sun, Cuijuan Shi, Dan Hua, Lin Yu, Yanjun Wen, Feng Hua, Qian Wang, Qinghua Zhou, Shizhu Yu
Quaking-5 (QKI-5) belongs to the STAR (signal transduction and activation of RNA) family of RNA binding proteins and functions as a tumor suppressor in several human malignancies. In this study, we attempt to elucidate the role of QKI-5 in the pro-metastasis processes of lung cancer (LC) cells and the underlying mechanisms. We confirmed that QKI-5 was decreased in human LC tissues and cell lines, especially in high-metastatic cells. Moreover, QKI expression was positively correlated with LC patients' survival...
October 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29135660/preferably-not-my-surgery-a-survey-of-patient-and-family-member-comfort-with-concurrent-and-overlapping-surgeries
#20
Jonathan P Edgington, Michael E Petravick, Olumuyiwa A Idowu, Michael J Lee, Lewis L Shi
BACKGROUND: Concurrent and overlapping surgical procedures are a timely topic. The 2 largest publications on the topic were limited to a journalistic overview and a government committee report. Since then, a recent survey of paid individuals found that they disapprove of overlapping surgical procedures in many cases. Still, we are aware of no work that specifically polled patients and their family members about their beliefs on concurrent and overlapping surgical procedures. We hypothesized that patients and family members will be uncomfortable with 1 surgeon performing overlapping or concurrent surgical procedures...
November 15, 2017: Journal of Bone and Joint Surgery. American Volume
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