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https://www.readbyqxmd.com/read/28524897/transgender-patient-screening-breast-cancer-risk-assessment-and-screening-recommendations%C3%A2
#1
Deirdre Kiely
BACKGROUND: When a discrepancy exists between an individual's biologic sex and the deeply felt sense of being male or female, a transgender orientation may result. 
. OBJECTIVES: The purpose of this article is to summarize breast cancer risk assessment and screening recommendations for transgender individuals. 
. METHODS: A review of the literature was done to determine if evidence-based screening guidelines exist for transgender individuals and how they can be applied to clinical practice...
June 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28524765/what-can-critical-suicidology-do
#2
Jennifer White
Critical suicidology is an emerging area of scholarship and praxis that brings together academics, community activists, service users, practitioners, policy makers, family members and persons with lived experience, to rethink what it means to study suicide and enact practices of suicide prevention in more diverse and creative, less psycho-centric and less depoliticized, ways. In this paper I begin to articulate what it might mean to "think like a critical suicidologist," the questions that might get asked from this position, the academic and activist allies who might get recruited to the cause, and the potential cracks we might open up in pursuit of a more hopeful, life-affirming, and just future...
May 19, 2017: Death Studies
https://www.readbyqxmd.com/read/28523498/maldi-msi-analysis-of-cytological-smears-the-study-of-thyroid-cancer
#3
Niccolò Mosele, Andrew Smith, Manuel Galli, Fabio Pagni, Fulvio Magni
Fine needle aspiration (FNA) biopsies are the current gold-standard for the preoperative evaluation of thyroid nodules. However, a significant number of them (15-30%) are unable to be affirmatively diagnosed and are given an "indeterminate for malignancy" final report, meaning that the malignant nature of the thyroid nodule remains unknown and the recommended therapeutic approach is total thyroidectomy. Furthermore, cytomorphological evaluation of biopsies taken post-surgery indicates that approximately 80% of nodules within this group of patients are in fact benign, and the total thyroidectomy unwarranted...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28514530/curious-thoughtful-and-affirmative-young-children-s-meanings-of-participation-in-healthcare-situations-when-using-an-interactive-communication-tool
#4
Anna Stålberg, Anette Sandberg, Thomas Larsson, Imelda Coyne, Maja Söderbäck
AIM: to describe young children's demonstrated participation in healthcare situations while using an interactive communication tool. BACKGROUND: participation is a multidimensional concept influenced by situational and contextual issues. In child participation, verbal and non-verbal communicative expressions are of interest, as both demonstrate the child's perspective. Children have a right to participate in all situations that matter to them, for instance healthcare situations...
May 17, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28513292/analysis-of-cutting-oil-emulsion-destabilization-by-aluminium-sulfate
#5
Nattawin Chawaloesphonsiya, Pascal Guiraud, Pisut Painmanakul
The destabilization mechanism of the high stable cutting-oil emulsion by aluminium sulfate (Al2(SO4)3) was investigated since it can affect properties of aggregates and following separation units. Al2(SO4)3 dosage and pH were key factors in the destabilization. The effective separation occurred when precipitated Al(OH)3 is dominated at the neutral pH of 6.5-7.0. The best separation can be achieved when solid flocs were formed at 1.0 mM, which exceeded the dosage from the CCC of 0.75 mM. Two different mechanisms were proved for the emulsion destabilization depending upon the Al(3+) concentration under this pH range...
May 17, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28511167/gut-microbiota-changes-as-a-risk-factor-for-obesity
#6
Krystyna B Kvit, Natalia V Kharchenko
INTRODUCTION: The number of obese people in recent decades is increasing significantly. Among the many aspects of obesity in the last decade, the role and importance of changes in the gut microbiota (GM) attracts special attention. The aim of the review was to analyze the results of studies, focused on the role of gut microbiota in the obesity development. MATERIALS AND METHODS: Screening was conducted on 33 researches, which examined the role of the gut microbiota balance in the development of obesity...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28510577/are-horses-capable-of-mirror-self-recognition-a-pilot-study
#7
Paolo Baragli, Elisa Demuru, Chiara Scopa, Elisabetta Palagi
Mirror Self-Recognition (MSR) unveils complex cognitive, social and emotional skills and it has been found only in humans and few other species, such as great apes, dolphins, elephants and magpies. In this pilot study, we tested if horses show the capacity of MSR. Four subjects living socially under naturalistic conditions were selected for the experiment. We adopted the classical mark test, which consists in placing a coloured mark on an out-of-view body part, visible only through mirror inspection. If the animal considers the image as its own, it will use its reflection to detect the mark and will try to explore it...
2017: PloS One
https://www.readbyqxmd.com/read/28506803/peg-coated-and-doxorubicin-loaded-multimodal-gadolinium-oxide-nanoparticles-for-simultaneous-drug-delivery-and-imaging-applications
#8
Shailja Kumar, Virendra Kumar Meena, Puja Panwar Hazari, Rakesh Kumar Sharma
We report water-in-oil microemulsion mediated synthesis of polyethylene glycol (PEG(1)) coated Gd2O3 nanoparticles (NPs(2)) loaded with fluorescent anti-cancer drug doxorubicin (dox(3)) for synchronous drug delivery, optical and magnetic resonance (MR(4)) imaging applications. These PEG covered Gd2O3 NPs loaded with dox (Gd-PEG-dox NPs) were found to possess spherical morphology with 13nm size as measured from TEM and the hydrodynamic diameter comes out to be 37nm as determined from DLS. Fluorescence spectra and fluorescence microscopy images confirmed optical activity of the NPs...
May 12, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28506127/living-into-death-a-case-for-an-iterative-fortified-and-cross-sector-approach-to-advance-care-planning
#9
Rebecca Llewellyn, Chrystal Jaye, Richard Egan, Wayne Cunningham, Jessica Young, Peter Radue
Advance care planning (ACP) has been framed as best practice for quality palliative care, yet a growing body of literature affirms the need for an early iterative ACP process to begin when people are young and healthy. A significant gap appears to exist in the literature regarding the utility of death conversations outside the end-of-life context. Could 'death conversations' early in life be an effective tool by which doctor and patient can co-construct a more healthful way of life, and realistic relationship with death? And what variables must be taken into account for these conversations to proceed successfully? This paper provides a narrative exploration of the value of death conversations in the clinical context in New Zealand...
May 16, 2017: Anthropology & Medicine
https://www.readbyqxmd.com/read/28504531/the-role-of-familiarity-in-correcting-inaccurate-information
#10
Briony Swire, Ullrich K H Ecker, Stephan Lewandowsky
People frequently continue to use inaccurate information in their reasoning even after a credible retraction has been presented. This phenomenon is often referred to as the continued influence effect of misinformation. The repetition of the original misconception within a retraction could contribute to this phenomenon, as it could inadvertently make the "myth" more familiar-and familiar information is more likely to be accepted as true. From a dual-process perspective, familiarity-based acceptance of myths is most likely to occur in the absence of strategic memory processes...
May 15, 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
https://www.readbyqxmd.com/read/28502912/thinking-styles-and-quality-of-university-life-among-deaf-or-hard-of-hearing-and-hearing-students
#11
Sanyin Cheng, Li-Fang Zhang
The authors explored how thinking styles relate to quality of university life among deaf or hard of hearing (DHH) and hearing university students in mainland China. The first of two studies affirmed the validity and reliability of a modified version of the Quality of University Life Measure (QULM; Sirgy, Grezskowiak, & Rahtz, 2007) among 833 university students (366 DHH, 467 hearing). The second investigated relationships between thinking styles and quality of university life; the Thinking Styles Inventory-Revised II (Sternberg, Wagner, & Zhang, 2007) and modified QULM were administered to 542 students (256 DHH, 286 hearing)...
2017: American Annals of the Deaf
https://www.readbyqxmd.com/read/28501792/healing-ministry-and-palliative-care-in-christianity
#12
S Stephen Jayard, Nishant A Irudayadason, J Charles Davis
Death is inevitable, but that does not mean it can be planned or imposed. It is an ethical imperative that we attend to the unbearable pain and suffering of patients with incurable and terminal illnesses. This is where palliative care plays a vital role. Palliative care has been growing faster in the world of medicine since its emergence as a specialty in the last decade. Palliative care helps to reduce physical pain while affirming the aspect of human suffering and dying as a normal process. The goal of palliative care is to improve the quality of life both of the patient and the family...
May 3, 2017: Indian Journal of Medical Ethics
https://www.readbyqxmd.com/read/28501750/development-validation-and-application-of-a-novel-liquid-chromatography-tandem-mass-spectrometry-assay-measuring-uracil-5-6-dihydrouracil-5-fluorouracil-5-6-dihydro-5-fluorouracil-%C3%AE-fluoro-%C3%AE-ureidopropionic-acid-and-%C3%AE-fluoro-%C3%AE-alanine-in-human-plasma
#13
Ottiniel Chavani, Berit Packert Jensen, R Matthew Strother, Christopher M Florkowski, Peter M George
The plasma 5,6-dihydrouracil/uracil (UH2/U) ratio is a possible phenotypic marker of dihydropyrimidine dehydrogenase (DPD) activity, hence an index of 5-fluorouracil (5-FU) response and toxicity. Studies have re-affirmed the value of 5-FU and 5,6-dihydro-5-fluorouracil (FUH2) for therapeutic drug monitoring (TDM). However, FUH2 has limited stability in plasma, necessitating expedited plasma separation and freezing, where routine compliance may not be easy. The metabolites α-fluoro-β-ureidopropionic acid (FUPA) and α-fluoro-β-alanine (FβAL) are stable in plasma and are probable candidates for TDM...
May 6, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28499256/from-common-to-rare-zingiberaceae-plants-a-metabolomics-study-using-gc-ms
#14
Gina B Barbosa, Nirupama S Jayasinghe, Siria H A Natera, Ellen D Inutan, Nonita P Peteros, Ute Roessner
Zingiberaceae plants, commonly known as gingers, have been popular for their medicinal and culinary uses since time immemorial. In spite of their numerous health-promoting applications, many Zingiberaceae plants still receive no scientific attention. Moreover, existing reports mostly focused only on the Zingiberaceae rhizomes. Here, untargeted metabolite profiling using Gas Chromatography - Mass Spectrometry (GC-MS) was used to compare the metabolic composition of leaves and rhizomes of the more common gingers, Zingiber officinale Rosc...
May 9, 2017: Phytochemistry
https://www.readbyqxmd.com/read/28496355/cannabis-as-a-substitute-for-prescription-drugs-a-cross-sectional-study
#15
James M Corroon, Laurie K Mischley, Michelle Sexton
BACKGROUND: The use of medical cannabis is increasing, most commonly for pain, anxiety and depression. Emerging data suggest that use and abuse of prescription drugs may be decreasing in states where medical cannabis is legal. The aim of this study was to survey cannabis users to determine whether they had intentionally substituted cannabis for prescription drugs. METHODS: A total of 2,774 individuals were a self-selected convenience sample who reported having used cannabis at least once in the previous 90 days...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28496289/what-if-reading-is-easy-but-unimportant-how-students-patterns-of-affirming-and-undermining-motivation-for-reading-information-texts-predict-different-reading-outcomes
#16
Emily Q Rosenzweig, Allan Wigfield
Many affirming and undermining motivational constructs affect students as they read information texts, but few researchers have explored how these motivations are patterned within students. In this study we used cluster analysis to classify middle school students (n = 1,134) based on their patterns of self-efficacy, perceived difficulty, value, and devalue for reading school information texts. We then compared how the patterns predicted students' language arts grades, science information text comprehension, and dedication to reading school information texts...
January 2017: Contemporary Educational Psychology
https://www.readbyqxmd.com/read/28493970/elevation-of-secondary-metabolites-synthesis-in-brassica-campestris-ssp-chinensis-l-via-exogenous-inoculation-of-piriformospora-indica-with-appropriate-fertilizer
#17
Muhammad Khalid, Danial Hassani, Muhammad Bilal, Jianli Liao, Danfeng Huang
This work evaluated the impact of exogenous soil inoculation of beneficial fungal strain Piriformospora indica on phytochemical changes and the related genes expression of Chinese cabbage (Brassica campestris ssp. chinensis L.) by greenhouse pot experiments. High performance liquid chromatography (HPLC) affirmed that among the different combinations of fungal and organic fertilizer treatments, the phenolic acids and flavonoids were considerably enriched in organic fertilizer and fungi (OP) followed by organic fertilizer, biochar, fungi (OBP) treated plants...
2017: PloS One
https://www.readbyqxmd.com/read/28493826/targeting-the-apoptotic-mcl-1-puma-interface-with-a-dual-acting-compound
#18
Jiyuan Liu, Zhen Tian, Nan Zhou, Xueying Liu, Chenyi Liao, Beilei Lei, Jianing Li, Shengyong Zhang, Hui Chen
Despite intensive efforts in the search for small molecules with anti-cancer activity, it remains challenging to achieve both high effectiveness and safety, since many agents lack the selectivity to only act on cancer cells. The interface of two apoptotic proteins, myeloid cell leukemia-1 (Mcl-1) and p53 upregulated modulator of apoptosis (PUMA), has been recently affirmed as a target for treating cancers, as the disruption of Mcl-1-PUMA binding can reduce cancer cell survival and protect normal cells from apoptosis...
April 20, 2017: Oncotarget
https://www.readbyqxmd.com/read/28493658/factors-associated-with-delayed-diagnosis-of-mood-and-or-anxiety-disorders
#19
Ricky Cheung, Siobhan O'Donnell, Nawaf Madi, Elliot Goldner
INTRODUCTION: This study examined the association between time to diagnosis and sociodemographic and clinical characteristics as well as time to diagnosis and physical and mental health status, among Canadian adults with a self-reported mood and/or anxiety disorder diagnosis. METHODS: We used data from the 2014 Survey on Living with Chronic Diseases in Canada-Mood and Anxiety Disorders Component. The study sample (n=3212) was divided into three time to diagnosis subgroups: long (> 5 years), moderate (1-5 years) and short (< 1 year)...
May 2017: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/28493492/dehydroacetic-acid-derivatives-bearing-amide-and-urea-moieties-as-effective-anion-receptors
#20
Nikola Bregovic, Nikola Cindro, Branimir Bertoša, Dajana Barišić, Leo Frkanec, Krunoslav Užarević, Vladislav Tomišić
Three novel derivatives of dehydroacetic acid comprising amide and urea subunits were synthesized and their anion binding properties investigated. The studied compounds selectively bind acetate and dihydrogen phosphate in acetonitrile and dimethyl sulfoxide among a series of halides and oxyanions. The corresponding complexation processes were characterized by means of 1H NMR titrations revealing the 1:1 complex stoichiometry in most cases, with the exception of dihydrogen phosphate which formed 2:1 (anion:ligand) complexes in acetonitrile...
May 11, 2017: Chemistry: a European Journal
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