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transvaginal mesh complications

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https://www.readbyqxmd.com/read/28010993/adverse-events-after-first-single-mesh-and-non-mesh-surgical-procedures-for-stress-urinary-incontinence-and-pelvic-organ-prolapse-in-scotland-1997-2016-a-population-based-cohort-study
#1
Joanne R Morling, David A McAllister, Wael Agur, Colin M Fischbacher, Cathryn M A Glazener, Karen Guerrero, Leanne Hopkins, Rachael Wood
BACKGROUND: Concerns have been raised about the safety of surgery for stress urinary incontinence and pelvic organ prolapse using transvaginal mesh. We assessed adverse outcomes after first, single mesh procedures and comparable non-mesh procedures. METHODS: We did a cohort study of women in Scotland aged 20 years or older undergoing a first, single incontinence procedure or prolapse procedure during 1997-98 to 2015-16 identified from a national hospital admission database...
December 20, 2016: Lancet
https://www.readbyqxmd.com/read/28010989/mesh-graft-or-standard-repair-for-women-having-primary-transvaginal-anterior-or-posterior-compartment-prolapse-surgery-two-parallel-group-multicentre-randomised-controlled-trials-prospect
#2
Cathryn Ma Glazener, Suzanne Breeman, Andrew Elders, Christine Hemming, Kevin G Cooper, Robert M Freeman, Anthony Rb Smith, Fiona Reid, Suzanne Hagen, Isobel Montgomery, Mary Kilonzo, Dwayne Boyers, Alison McDonald, Gladys McPherson, Graeme MacLennan, John Norrie
BACKGROUND: The use of transvaginal mesh and biological graft material in prolapse surgery is controversial and has led to a number of enquiries into their safety and efficacy. Existing trials of these augmentations are individually too small to be conclusive. We aimed to compare the outcomes of prolapse repair involving either synthetic mesh inlays or biological grafts against standard repair in women. METHODS: We did two pragmatic, parallel-group, multicentre, randomised controlled trials for our study (PROSPECT [PROlapse Surgery: Pragmatic Evaluation and randomised Controlled Trials]) in 35 centres (a mix of secondary and tertiary referral hospitals) in the UK...
December 20, 2016: Lancet
https://www.readbyqxmd.com/read/27980522/ultrasound-imaging-in-urogynecology-state-of-the-art-2016
#3
Michał Bogusiewicz
The role of ultrasound imaging in urogynecology is not clearly defined. Despite significant developments in visualization techniques and interpretation of images, pelvic ultrasound is still more a tool for research than for clinical practice. Structures of the lower genitourinary tract and pelvic floor can be visualized from different approaches: transperineal, introital, transvaginal, abdominal or endoanal. According to contemporary guidelines and recommendations, the role of ultrasound in urogynecology is limited to the measurement of post-void residue...
November 2016: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/27942792/transvaginal-uterosacral-ligament-hysteropexy-a-video-tutorial
#4
Rodolfo Milani, Matteo Frigerio, Federico Spelzini, Stefano Manodoro
INTRODUCTION AND HYPOTHESIS: Uterine-sparing procedures could be attractive in patients concerned about fertility preservation and corporeal image changes. Transvaginal uterosacral ligaments (USLs) hysteropexy can provide a mesh-free technique for uterine suspension. This video is intended to serve as a tutorial for surgical steps. METHODS: A 38-year-old woman with symptomatic stage III POP desired preserving fertility. After proper counseling, the patient was admitted for vaginal hysteropexy through bilateral high USL suspension according to the featured technique...
December 10, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27902825/association-between-the-amount-of-vaginal-mesh-used-with-mesh-erosions-and-repeated-surgery-after-repairing-pelvic-organ-prolapse-and-stress-urinary-incontinence
#5
Bilal Chughtai, Matthew D Barber, Jialin Mao, James C Forde, Sharon-Lise T Normand, Art Sedrakyan
Importance: Mesh, a synthetic graft, has been used in pelvic organ prolapse (POP) repair and stress urinary incontinence (SUI) to augment and strengthen weakened tissue. Polypropylene mesh has come under scrutiny by the US Food and Drug Administration. Objective: To examine the rates of mesh complications and invasive reintervention after the placement of vaginal mesh for POP repair or SUI surgery. Design, Setting, and Participants: This investigation was an observational cohort study at inpatient and ambulatory surgery settings in New York State...
November 30, 2016: JAMA Surgery
https://www.readbyqxmd.com/read/27886523/two-years-follow-up-of-270-patients-treated-by-transvaginal-mesh-for-anterior-and-or-apical-prolapse
#6
Florence Hugele, Laure Panel, Camille Farache, Amgad Kashef, Arnaud Cornille, Christophe Courtieu
OBJECTIVE: The aim of this study was to assess the 1 and 2 years outcomes of transvaginal single incision mesh surgery (SIMS) for anterior pelvic organ prolapse (POP). MATERIAL AND METHODS: This was a prospective study including all patients from November 2008 to December 2012 who underwent SIMS for symptomatic anterior prolapse stage≥2, according to the POP Quantification (POP-Q). Symptoms and quality of life were assessed using validated questionnaires: Pelvic Floor Distress Inventory (PFDI-20), Pelvic Floor Impact questionnaire (PFIQ-7), and Prolapse/Incontinence Sexual Questionnaire (PISQ-12)...
January 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27866958/use-of-concomitant-stress-incontinence-surgery-at-time-of-pelvic-organ-prolapse-surgery-since-release-of-the-2011-fda-health-notification-on-serious-complications-associated-with-transvaginal-mesh
#7
Alice Drain, Aqsa Khan, Erin L Ohmann, Benjamin M Brucker, Scott Smilen, Nirit Rosenblum, Victor W Nitti
PURPOSE: There is controversy regarding performing concomitant anti-incontinence procedures at the time of pelvic organ prolapse (POP) repair. Data supports improvement in stress urinary incontinence (SUI) with concomitant sling, but increased adverse events. We assessed trends in preoperative SUI evaluation, concomitant anti-incontinence procedure at POP surgery, and post-operative anti-incontinence procedures at our institution before and after the 2011 FDA Public Health Notification pertaining to vaginal mesh...
November 17, 2016: Journal of Urology
https://www.readbyqxmd.com/read/27833469/a-novel-approach-to-mesh-revision-after-sacrocolpopexy
#8
Melissa L Dawson, Rinko Rebecca, Nima M Shah, Kristene E Whitmore
Pelvic organ prolapse (POP) is the herniation of pelvic organs to or beyond the vaginal walls. POP affects 50% of parous women; of those women, 11% will need surgery based on bothersome symptoms. Transvaginal mesh has been used for vaginal augmentation since the 1990s. Complications from mesh use are now more prominent, and include chronic pelvic pain, dyspareunia, vaginal mesh erosion, and urinary and defecatory dysfunction. Presently, there is no consensus regarding treatment of these complications. Reported herein are two cases of women with defecatory dysfunction and pain after sacrocolpopexy who underwent mesh revision procedures performed with both urogynecologic and colorectal surgery...
2016: Reviews in Urology
https://www.readbyqxmd.com/read/27780347/indications-and-complications-associated-with-the-removal-of-506-pieces-of-vaginal-mesh-used-in-pelvic-floor-reconstruction-a-multicenter-study
#9
John R Miklos, Orawee Chinthakanan, Robert D Moore, Deborah R Karp, Gladys M Nogueiras, G Willy Davila
STUDY OBJECTIVE: Synthetic mesh utilized to treat stress urinary incontinence (SUI) and pelvic organ prolapse (POP) can often result in postoperative complications. The objectives of this study were to determine: 1) the most common indications for mesh removal; 2) the incidences of the removal of specific mesh procedures (such as suburethral sling [SUS], transvaginal mesh [TVM], or sacrocolpopexy); and 3) the idences and types of surgical complications associated with mesh removal. DESIGN: This was a retrospective study...
October 26, 2016: Surgical Technology International
https://www.readbyqxmd.com/read/27773649/postoperative-urinary-retention-and-urinary-tract-infections-predict-midurethral-sling-mesh-complications
#10
Nahid Punjani, Jennifer Winick-Ng, Blayne Welk
OBJECTIVE: To determine if postoperative urinary retention and urinary tract infections (UTIs) were predictors of future mesh complications requiring surgical intervention after midurethral sling (MUS). MATERIALS AND METHODS: Administrative data in Ontario, Canada, between 2002 and 2013 were used to identify all women who underwent a mesh-based MUS. The primary outcome was revision of the transvaginal mesh sling (including mesh removal/erosion/fistula, or urethrolysis)...
January 2017: Urology
https://www.readbyqxmd.com/read/27762470/association-of-urodynamics-and-lower-urogenital-tract-nerve-growth-factor-after-synthetic-vaginal-mesh-implantation-on-a-rat-model
#11
Tsia-Shu Lo, Yi-Hao Lin, Hsiao-Chien Chu, Eileen Feliz M Cortes, Leng Boi Pue, Yiap Loong Tan, Ma Clarissa Uy-Patrimonio
AIM: By investigating the association of urodynamics and urogenital nerve growth factor (NGF) levels in vaginal mesh surgery, we may be able to associate the likelihood of postoperative lower urinary tract symptoms developing as a result of synthetic mesh implanted for pelvic floor reconstructive surgery. METHODS: Thirty-eight female Sprague-Dawley rats were divided into three groups: mesh, sham (no mesh), and control. Urodynamic study and NGF analysis of the urogenital tissues were done and results were compared among all groups...
October 20, 2016: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/27757813/reasons-for-and-against-use-of-non-absorbable-synthetic-mesh-during-pelvic-organ-prolapse-repair-according-to-the-prolapsed-compartment
#12
REVIEW
Stavros Kontogiannis, Evangelia Goulimi, Konstantinos Giannitsas
Awareness and reporting of mesh-related complications of pelvic organ prolapse repairs have increased in recent years. As a result, deciding whether to use a mesh or not has become a difficult task for urogynecologists. Our aim was to summarize reasons for and against the use of mesh in prolapse repair based on a review of relevant literature. Scopus and PubMed databases were searched for papers reporting on the efficacy and safety of native tissue versus non-absorbable, synthetic mesh prolapse repairs. Randomized controlled trials, systematic reviews, and meta-analyses were included...
January 2017: Advances in Therapy
https://www.readbyqxmd.com/read/27636217/analysis-of-surgical-outcomes-and-determinants-of-litigation-among-women-with-transvaginal-mesh-complications
#13
Dani Zoorob, Mickey Karram, Anna Stecher, Rose Maxwell, James Whiteside
OBJECTIVES: To identify litigation predictors among women with complications of transvaginal mesh. METHODS: Chart review and patient survey were conducted among women who had undergone a complication-related explant of a transvaginal prolapse or incontinence sling mesh. Trained study personnel administered a 57-question survey addressing subjective complaints related to bowel, bladder, sexual dysfunction, and development of pain or recurrent prolapse. These data were analyzed with respect to the subject's reported pursuit of litigation related to the mesh complication...
September 16, 2016: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/27619780/anatomical-and-functional-outcomes-of-prolift-transvaginal-mesh-for-treatment-of-pelvic-organ-prolapse
#14
Wan Song, Tae Heon Kim, Jin Woo Chung, Won Jin Cho, Ha Na Lee, Young Suk Lee, Kyu-Sung Lee
OBJECTIVES: To evaluate anatomical and functional outcomes of the Prolift Transvaginal Mesh for treatment of pelvic organ prolapse (POP) with regard to safety and satisfaction. METHODS: We reviewed the medical records of 163 patients who underwent POP repair with Prolift Transvaginal Mesh between December 2005 and March 2012. An "optimal" anatomic outcome was defined as Pelvic Organ Prolapse Quantification System (POP-Q) stage 0, and a "satisfactory" anatomic outcome was defined as POP-Q stage 1...
September 2016: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/27562466/mesh-complications-and-failure-rates-after-transvaginal-mesh-repair-compared-with-abdominal-or-laparoscopic-sacrocolpopexy-and-to-native-tissue-repair-in-treating-apical-prolapse
#15
Vani Dandolu, Megumi Akiyama, Gayle Allenback, Prathamesh Pathak
OBJECTIVE: Our objective was to quantitate the extent of complications and failure rate for apical prolapse repair with transvaginal mesh (TVM) use versus sacrocolpopexy over a minimum of 2 years of follow-up. METHODS: Truven CCAE and Medicare Supplemental databases 2008-2013 were used for analysis. Patients with apical prolapse repair via transvaginal mesh (TVMR), abdominal sacrocolpopexy (ASCP), laparoscopic sacrocolpopexy (LSCP), or native tissue repair (NTR) and continuously enrolled for years were in the study cohort...
August 25, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27549225/transvaginal-mesh-a-historical-review-and-update-of-the-current-state-of-affairs-in-the-united-states
#16
Shilpa Iyer, Sylvia M Botros
INTRODUCTION: Transvaginal mesh usage has been at the forefront of popular media and academic debate for the past 10 years. Several US Food and Drug Administration (FDA) communications, society statements, and research articles have been written in an attempt to define and articulate the classification system, safety data, and efficacy of this approach to transvaginal surgery. In this review, we explore the history of transvaginal mesh surgery for pelvic organ prolapse (POP), review FDA and society statements, and research current practice in the United States...
August 22, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27530521/transvaginal-sling-excision-tips-and-tricks
#17
Marisa M Clifton, Howard B Goldman
INTRODUCTION AND HYPOTHESIS: Complications of synthetic midurethral sling surgery include bladder outlet obstruction, mesh extrusion, and vaginal pain. A treatment of these complications is transvaginal mesh removal. The objectives of this video are to present cases of complications after sling placement and describe techniques to help with successful sling removal. METHODS: Three patients are presented in this video. One experienced urinary hesitancy and was found to have bladder outlet obstruction on urodynamic study...
January 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/27517341/exploring-the-basic-science-of-prolapse-meshes
#18
Rui Liang, Katrina Knight, Steve Abramowitch, Pamela A Moalli
PURPOSE OF REVIEW: Polypropylene mesh has been widely used in the surgical repair of pelvic organ prolapse. However, low but persistent rates of complications related to mesh, most commonly mesh exposure and pain, have hampered its use. Complications are higher following transvaginal implantation prompting the Food and Drug Administration to release two public health notifications warning of complications associated with transvaginal mesh use (PHN 2008 and 2011) and to upclassify transvaginal prolapse meshes from Class II to Class III devices...
October 2016: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27465100/quality-of-life-in-women-of-non-reproductive-age-with-transvaginal-mesh-repair-for-pelvic-organ-prolapse-a-cohort-study
#19
Tanja Hüsch, René Mager, Erika Ober, Ralf Bentler, Kurt Ulm, Axel Haferkamp
BACKGROUND: Transvaginal mesh repair has been discredited due to high complications rates in the past years. Therefore, we evaluated the quality of life (QoL) and complication rates after transvaginal mesh (TVM) repair for pelvic organ prolapse (POP). METHODS: A total of 148 women who underwent TVM repair for symptomatic POP were retrospectively enrolled. Complication rates and functional outcomes were retrospectively assessed and validated, standardised questionnaires were used prospectively for evaluation of QoL...
September 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/27460448/stress-urinary-incontinence-surgery-trends-in-academic-female-pelvic-medicine-and-reconstructive-surgery-urology-practice-in-the-setting-of-the-food-and-drug-administration-public-health-notifications
#20
Goran Rac, Austin Younger, James Q Clemens, Kathleen Kobashi, Aqsa Khan, Victor Nitti, Ilana Jacobs, Gary E Lemack, Elizabeth T Brown, Roger Dmochowski, Lara MacLachlan, Arthur Mourtzinos, David Ginsberg, Michelle Koski, Ross Rames, Eric S Rovner
AIMS: To investigate the possible effects of the Food and Drug Administration (FDA) Public Health Notifications in 2008 and 2011 regarding surgical trends in transvaginal mesh (TVM) placement for stress urinary incontinence (SUI) and related mesh revision surgery in Female Pelvic Medicine & Reconstructive Surgery (FPMRS) practice in tertiary care academic medical centers in the United States. METHODS: Surgical volume for procedures performed primarily by FPMRS surgeons at eight academic institutions across the US was collected using Current Procedural Terminology (CPT) codes for stress urinary incontinence repair and revision surgeries from 2007 to 2013...
July 26, 2016: Neurourology and Urodynamics
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