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Emilija Stojanović, Nikola Aksović, Nenad Stojiljković, Ratko Stanković, Aaron T Scanlan, Zoran Milanović
Stojanović, E, Aksović, N, Stojiljković, N, Stanković, R, Scanlan, AT, and Milanović, Z. Reliability, usefulness, and factorial validity of change-of-direction speed tests in adolescent basketball players. J Strength Cond Res XX(X): 000-000, 2018-The purposes of this study were to (1) determine the reliability, usefulness, and factorial validity of change-of-direction speed (CODS) tests in adolescent basketball players and (2) evaluate positional differences in test performances. Elite, adolescent male basketball players (n = 53; 17...
June 20, 2018: Journal of Strength and Conditioning Research
Naglaa A Mostafa, Magda Assaf, Sami Elhakim, Mona R E Abdel-Halim, Eman El-Nabarawy, Khaled Ghareeb
BACKGROUND: The distinction of trichoepithelioma from basal cell carcinoma in small superficial biopsies is important but often challenging. This has inspired many scientists to test the validity of immunohistochemical markers in the differential diagnosis. OBJECTIVES: to develop an immunohistochemical protocol that helps in differentiation between both TE and BCC with higher sensitivity and specificity. METHODS: Using standard immunohistochemical techniques, we examined 10 TEs and 19 BCCs for the expression of CK19, Ki67, Androgen receptors (AR), CD10, and PHLDA1...
June 19, 2018: Journal of Cutaneous Pathology
Fenghua Ding, Matthew L Nisbet, Hongwei Yu, Weiguo Zhang, Liyuan Chai, P Shiv Halasyamani, Kenneth R Poeppelmeier
Single crystals of two new metal tellurates Bi MTeO6 ( M = Al, Ga) with a honeycomb layered structure were obtained by the molten flux method and characterized. The Bi MTeO6 compounds both crystallize into a non-centrosymmetric trigonal space group of P312 (no. 149) with cell parameters of a = 5.0667(8) Å, c = 4.9920(16) Å and a = 5.107(3) Å, c = 4.932(6) Å, respectively. The non-centrosymmetry of BiAlTeO6 and BiGaTeO6 originates from the packing order of the octahedra. In these two structures, TeO6 octahedra and MO6 octahedra share edges and form a honeycomb open-framework with [Te MO6 ]∞ layers...
June 15, 2018: Inorganic Chemistry
Julia M Jones, Darren J Player, Neil R W Martin, Andrew J Capel, Mark P Lewis, Vivek Mudera
There are several three-dimensional (3D) skeletal muscle (SkM) tissue engineered models reported in the literature. 3D SkM tissue engineering (TE) aims to recapitulate the structure and function of native ( in vivo ) tissue, within an in vitro environment. This requires the differentiation of myoblasts into aligned multinucleated myotubes surrounded by a biologically representative extracellular matrix (ECM). In the present work, a new commercially available 3D SkM TE culture chamber manufactured from polyether ether ketone (PEEK) that facilitates suitable development of these myotubes is presented...
2018: Frontiers in Physiology
Xiuyuan Chen, Bensheng Qiu
PURPOSE: Ultrashort echo time (UTE) sequences play a key role in imaging and quantifying short T2 species. However, almost all of the relevant studies was conducted at relatively high fields. The purpose of this work was to further explore the feasibility of UTE imaging and T2* measurement for short T2 species at low fields. METHODS: A 2D UTE sequence with an echo time (TE) of 0.37 ms was developed on a 0.35 T permanent magnet scanner. This sequence acquires multiecho images to fit the monoexponential signal decay model for quantitative T2* calculations...
June 4, 2018: Biomedical Engineering Online
Mingxia Zhang, Lili Yuan, Fucheng Yao, Ping Cao, Jianrong Rong, Bin Zhang, Jie Su
BACKGROUND: Human epididymis protein 4 (HE4) is an emerging fibrotic biomarker which has been studied in chronic kidney disease cohorts. However, it is unclear if the serum level of HE4 may be altered in patients with liver fibrosis and cirrhosis. METHODS: we assessed serum HE4 concentrations in patients (n = 366) with chronic liver diseases (CLD) and compared to matched healthy controls (n = 366). Liver stiffness measurement (LSM) by transient elastography (TE, FibroScan) was also performed on all patients...
June 1, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
Ching-Bin Ke, Te-Ling Lu, Jian-Lian Chen
Oxygen and nitrogen capacitively coupled plasma (CCP) was used to irradiate mixtures of aliphatic acids in high boiling point solvents to synthesize fluorescent carbon dots (C-dots). With a high fluorescence intensity, the C-dots obtained from the O₂/CCP radiation of a 1-ethyl-3-methylimidazolium dicyanamide ionic liquid solution of citric acid were characterized with an average diameter of 8.6 nm (σ = 1.1 nm), nitrogen and oxygen bonding functionalities, excitation-independent emissions, and upconversion fluorescence...
May 26, 2018: Nanomaterials
Felicia M Bloemendaal, Pim J Koelink, Karin A van Schie, Theo Rispens, Charlotte P Peters, Christianne J Buskens, Jarmila D van der Bilt, Willem A Bemelman, Hannelie Korf, João G Sabino, Cyriel Y Ponsioen, Anje A Te Velde, Geert R A M D'Haens, Gijs R van den Brink, Manon E Wildenberg
Background and Aims: We have recently shown that the mode of action of IgG1 anti-TNF antibodies in inflammatory bowel disease (IBD) requires Fcγ-receptor (FcR) engagement on macrophages. Here we examine the effect of Fcγ-receptor signaling by anti-TNF on macrophage IL-12/IL-23 secretion. Methods: Cytokine production by human inflammatory macrophages was assessed at the level of RNA and or protein. TNF-anti-TNF immune complex formation was determined by size-exclusion chromatography and signaling visualized by immunofluorescence...
May 30, 2018: Journal of Crohn's & Colitis
Rodolfo César de Oliveira Anderson, Rafael Parelli Bovo, Denis Vieira Andrade
As ectotherms, amphibians may exhibit changes in their thermal biology associated with spatial and temporal environmental contingencies. However, our knowledge on how amphibian´s thermal biology responds to seasonal changes in the environment is restricted to a few species, mostly from temperate regions, in a marked contrast with the high species diversity found in the Neotropics. We investigated whether or not the seasonal variation in climatic parameters from a high-montane ombrophilous forest in the Brazilian Atlantic Forest could lead to concurrent adjustments in the thermal biology of the terrestrial toad Rhinella icterica...
May 2018: Journal of Thermal Biology
C L Donohoe, A W Phillips, E Flynn, C Donnison, C L Taylor, R C F Sinclair, D Saunders, A Immanuel, S M Griffin
Thoracic epidural (TE) analgesia has been the standard of care for transthoracic esophagectomy patients since the 1990s. Multimodal anesthesia using intrathecal diamorphine, local anesthetic infusion catheters (LAC) into the paravertebral space and rectus sheaths and intravenous opioid postoperatively represent an alternative option for postoperative analgesia. While TE can provide excellent pain control, it may inhibit early postoperative recovery by causing hypotension and reducing mobilization. The aim of this study is to determine whether multimodal analgesia with LAC was effective with respect to adequate pain management, and compare its impact on hypotension and mobility...
May 24, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
D K Jones, D C Alexander, R Bowtell, M Cercignani, F Dell'Acqua, D J McHugh, K L Miller, M Palombo, G J M Parker, U S Rudrapatna, C M W Tax
The key component of a microstructural diffusion MRI 'super-scanner' is a dedicated high-strength gradient system that enables stronger diffusion weightings per unit time compared to conventional gradient designs. This can, in turn, drastically shorten the time needed for diffusion encoding, increase the signal-to-noise ratio, and facilitate measurements at shorter diffusion times. This review, written from the perspective of the National Facility for In Vivo MR Imaging of Human Tissue Microstructure, an initiative to establish a shared 300 mT/m-gradient facility amongst the microstructural imaging community, describes ten advantages of ultra-strong gradients for microstructural imaging...
May 21, 2018: NeuroImage
Teng Fang, Xinbing Zhao, Tiejun Zhu
Half-Heusler (HH) compounds, with a valence electron count of 8 or 18, have gained popularity as promising high-temperature thermoelectric (TE) materials due to their excellent electrical properties, robust mechanical capabilities, and good high-temperature thermal stability. With the help of first-principles calculations, great progress has been made in half-Heusler thermoelectric materials. In this review, we summarize some representative theoretical work on band structures and transport properties of HH compounds...
May 19, 2018: Materials
Te-Ching Chen, Jennifer D Parker, Jason Clark, Hee-Choon Shin, Jennifer R Rammon, Vicki L Burt
This report describes the methods used to create NHANES 2011-2014 sample weights and variance units for the public-use data files, including sample weights for selected subsamples, such as the fasting subsample. The impacts of sample design changes on estimation for NHANES 2011-2014 and the addition of the NHANES National Youth Fitness Survey (NNYFS) 2012 are described. Approaches that data users can employ to modify sample weights when combining survey cycles or when combining subsamples are also included.
January 2018: Vital and Health Statistics. Series 2, Data Evaluation and Methods Research
Ali Pirasteh, Qing Yuan, Diego Hernando, Scott B Reeder, Ivan Pedrosa, Takeshi Yokoo
PURPOSE: To assess the reproducibility of biexponential R2 -relaxometry MRI for estimation of liver iron concentration (LIC) between proprietary and nonproprietary analysis methods. METHODS: This single-center retrospective study, approved by investigational review board and compliant with the Health Insurance Portability and Accountability Act, included 40 liver MRI exams in 38 subjects with suspected or known iron overload. From spin-echo images of the liver, acquired at 5 different echo times (TE = 6-18 ms), biexponential R2 maps were calculated using 1 proprietary (FerriScan, Resonance Health Ltd...
May 16, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
Yushuai Wang, Weiqi Liang, Tian Tang
The evolutionary dynamics of the conflict between transposable elements (TEs) and their host genome remain elusive. This conflict will be intense in stress-adapted plants as stress can often reactivate TEs. Mangroves reduce TE load convergently in their adaptation to intertidal environments and thus provide a unique opportunity to address the host-TE conflict and its interaction with stress adaptation. Using the mangrove Rhizophora apiculata as a model, we investigated methylation and short interfering RNA (siRNA) targeting patterns in relation to the abundance and age of long terminal repeat (LTR) retrotransposons...
May 15, 2018: New Phytologist
Ratna N G B Tan, Steffen C Pauws, Evelyne van Loon, Vivanne E H J Smits, Enrico Lopriore, Arjan B Te Pas
Background: Venous blood gas (VBG) is frequently used in the neonatal unit as alternative for capillary blood gas (CBG). However, studies reporting correlation are conflicting and data on interchangeability in neonates are lacking. Objective: We investigated the correlation and interchangeability of the components between VBG and CBG in infants admitted to the neonatal intensive care unit. Methods: In a prospective study in the neonatal unit in Leiden University Medical Center (Netherlands), simultaneously VBG and CBG were withdrawn in neonates when both venous puncture and intravenous access as blood gas monitoring was indicated...
2018: Frontiers in Pediatrics
A Sengottuvelan, P Balasubramanian, J Will, A R Boccaccini
Three dimensional TiO2 scaffolds are receiving renewed attention for bone tissue engineering (TE) due to their biocompatibility and attractive mechanical properties. However the bioactivity of these scaffolds is comparatively lower than that of bioactive glass or hydroxyapatite (HA) scaffolds. One strategy to improve bioactivity is to functionalize the surface of the scaffolds using biomolecules. Alkaline phosphatase (ALP) was chosen in this study due to its important role in the bone mineralization process...
June 2017: Bioactive Materials
Chia-Jen Liu, Te-Chun Yeh, Su-Hsuan Hsu, Chao-Mei Chu, Chih-Kuang Liu, Mingchih Chen, Sheng-Jean Huang
BACKGROUND: The scientific contributions (publications) and international influence (citations) from authors providing the palliative care (PC)-related literature has a limited number of bibliometric reports. We aimed to analyze PC-related literature using the Institute for Scientific Information Web of Science (WoS) database. METHODS: WoS database was used to retrieve publications with the following key words with title: "palliative care" OR "End of Life care" OR "terminal care...
January 1, 2018: American Journal of Hospice & Palliative Care
Konstantinos Konstantinou, Tae Hoon Lee, Felix C Mocanu, Stephen R Elliott
The radiation hardness of amorphous Ge2 Sb2 Te5 phase-change random-access memory material has been elucidated by ab initio molecular-dynamics simulations. Ionizing radiation events have been modeled to investigate their effect on the atomic and electronic structure of the glass. Investigation of the short- and medium-range order highlights a structural recovery of the amorphous network after exposure to the high-energy events modeled in this study. Analysis of the modeled glasses reveals specific structural rearrangements in the local atomic geometry of the glass, as well as an increase in the formation of large shortest-path rings...
May 7, 2018: Proceedings of the National Academy of Sciences of the United States of America
Kalen J Petersen, Jacqueline A Reid, Srijata Chakravorti, Meher R Juttukonda, Giulia Franco, Paula Trujillo, Adam J Stark, Benoit M Dawant, Manus J Donahue, Daniel O Claassen
The dentato-rubro-thalamic tract (DRTT) regulates motor control, connecting the cerebellum to the thalamus. This tract is modulated by deep-brain stimulation in the surgical treatment of medically refractory tremor, especially in essential tremor, where high-frequency stimulation of the thalamus can improve symptoms. The DRTT is classically described as a decussating pathway, ascending to the contralateral thalamus. However, the existence of a nondecussating (i.e. ipsilateral) DRTT in humans was recently demonstrated, and these tracts are arranged in distinct regions of the superior cerebellar peduncle...
May 4, 2018: NeuroImage
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