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JOURNAL ARTICLE
Luping Qu, Yong Luo, Cong Li, Zhengliang Du, Xie Li, Jiaolin Cui
CuInTe2 (CIT) is one of the typical ternary chalcogenides known for its characteristic mixed polyanionic/polycationic site defects, making it a subject of continuous interest in the field of thermoelectrics. In this work, we propose a chemical composition modulation strategy for CIT by alloying GeTe and then introducing a copper deficiency (denoted by VCu ). This strategy aims to unpin its Fermi level ( F r ) and shift F r into the valence band (VB) while simultaneously enabling coupling between the optical and acoustic phonon, thereby providing an extra phonon scattering path at low frequencies...
April 23, 2024: ACS Applied Materials & Interfaces
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JOURNAL ARTICLE
Thomas Pincez, Helder Fernandes, Mony Fahd, Marlène Pasquet, Wadih Abou Chahla, Jérome Granel, Stéphane Ducassou, Caroline Thomas, Nathalie Garnier, Eric Jeziorski, Sophie Bayart, Pascal Chastagner, Nathalie Cheikh, Corinne Guitton, Catherine Paillard, Julien Lejeune, Frédéric Millot, Valérie Li-Thiao Te, Coralie Mallebranche, Isabelle Pellier, Martin Castelle, Corinne Armari-Alla, Liana Carausu, Christophe Piguet, Joy Benadiba, Claire Pluchart, Jean-Louis Stephan, Marianna Deparis, Claire Briandet, Eric Doré, Aude Marie-Cardine, Vincent Barlogis, Guy Leverger, Sébastien Héritier, Nathalie Aladjidi, Thierry Leblanc
Refractory chronic immune thrombocytopenia (r-cITP) is one of the most challenging situations in chronic immune thrombocytopenia (cITP). Pediatric r-cITP is inconsistently defined in literature, contributing to the scarcity of data. Moreover, no evidence is available to guide the choice of treatment. We compared seven definitions of r-cITP including five pediatric definitions in 886 patients with cITP (median [min-max] follow-up 5.3 [1.0-29.3] years). The pediatric definitions identified overlapping groups of various sizes (4%-20%) but with similar characteristics (higher proportion of immunopathological manifestations [IM] and systemic lupus erythematosus [SLE]), suggesting that they adequately captured the population of interest...
April 23, 2024: American Journal of Hematology
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JOURNAL ARTICLE
C S M Wong, L L Y Mak, V K H Lee, R C L Lo, M M H Chung, F Chu, C K Yeung, M F Yuen, H H L Chan
INTRODUCTION: Methotrexate (MTX) is effective for treating psoriasis and psoriatic arthritis, but its potential hepatoxicity remains a concern. Liver biopsy, the gold standard for detecting MTX-induced liver injury, is invasive and carries considerable risk. Transient elastography (TE) offers a non-invasive alternative for detecting advanced liver fibrosis. This study investigated the performance of TE in detecting MTX-induced liver fibrosis among Chinese psoriasis patients, compared with liver biopsy...
April 2024: Hong Kong Medical Journal
#4
Olivia R Ortiz, Tara Norris
Many opportunistic infections (OIs) seen early in the human immunodeficiency virus (HIV) epidemic receded in prevalence with the advent of antiretroviral therapy (ART). Despite the availability of early detection and treatment of HIV as well as guidelines for near-universal screening, there remains a sizable population of individuals living with HIV who are not yet aware of their HIV status. These individuals are at risk for OIs such as toxoplasmosis, which would otherwise be preventable with ART and appropriate prophylaxis...
April 2024: Curēus
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JOURNAL ARTICLE
Calebe P Mendes, Wido R Albert, Zachary Amir, Marc Ancrenaz, Eric Ash, Badrul Azhar, Henry Bernard, Jedediah Brodie, Tom Bruce, Elliot Carr, Gopalasamy Reuben Clements, Glyn Davies, Nicolas J Deere, Yoan Dinata, Christl A Donnelly, Somphot Duangchantrasiri, Gabriella Fredriksson, Benoit Goossens, Alys Granados, Andrew Hearn, Jason Hon, Tom Hughes, Patrick Jansen, Kae Kawanishi, Margaret Kinnaird, Sharon Koh, Alice Latinne, Matthew Linkie, Federica Loi, Anthony J Lynam, Erik Meijaard, Jayasilan Mohd-Azlan, Jonathan H Moore, Senthilvel K S S Nathan, Dusit Ngoprasert, Wilson Novarino, Ilyas Nursamsi, Timothy O'Brien, Robert Ong, John Payne, Dolly Priatna, D Mark Rayan, Glen Reynolds, Rustam Rustam, Sasidhran Selvadurai, Amanda Shia, Muhammad Silmi, Pablo Sinovas, Kriangsak Sribuarod, Robert Steinmetz, Matthew J Struebig, Ronglarp Sukmasuang, Sunarto Sunarto, Tarmizi Tarmizi, Arjun Thapa, Carl Traeholt, Oliver R Wearn, Hariyo B Wibisono, Andreas Wilting, Seth Timothy Wong, Siew Te Wong, Jettie Word, Wen Xuan Chiok, Zainal Zahari Zainuddin, Matthew Scott Luskin
Information on tropical Asian vertebrates has traditionally been sparse, particularly when it comes to cryptic species inhabiting the dense forests of the region. Vertebrate populations are declining globally due to land-use change and hunting, the latter frequently referred as "defaunation." This is especially true in tropical Asia where there is extensive land-use change and high human densities. Robust monitoring requires that large volumes of vertebrate population data be made available for use by the scientific and applied communities...
April 22, 2024: Ecology
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JOURNAL ARTICLE
Mathieu Varache, Siân Rizzo, Edward J Sayers, Lucy Newbury, Anna Mason, Chia-Te Liao, Emilie Chiron, Nathan Bourdiec, Adam Jones, Donald J Fraser, Philip R Taylor, Arwyn T Jones, David W Thomas, Elaine L Ferguson
The acute kidney injury (AKI) and dose-limiting nephrotoxicity, which occurs in 20-60% of patients following systemic administration of colistin, represents a challenge in the effective treatment of multi-drug resistant Gram-negative infections. To reduce clinical toxicity of colistin and improve targeting to infected/inflamed tissues, we previously developed dextrin-colistin conjugates, whereby colistin is designed to be released by amylase-triggered degradation of dextrin in infected and inflamed tissues, after passive targeting by the enhanced permeability and retention effect...
April 18, 2024: RSC Pharm
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JOURNAL ARTICLE
Hakan Diler, Asuman Şahan, Kemal Alparslan Erman
OBJECTIVE: In this study, we develop a tool that can be used by tennis coaches to evaluate the groundstroke (forehand and backhand) technique of preadolescent tennis players. METHODS: The participants of the study were 60 children (30 males and 30 females) aged 10-12 years, with at least two years of training in tennis. The Groundstroke Correction Checklist (GCC) was translated into Turkish by using a blind procedure. The Turkish translation was then evaluated by 15 coaches of the Turkish Tennis Federation who had at least a level-3 coaching license and more than five years of coaching experience...
2024: Frontiers in sports and active living
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Neil E Wilson, Mark A Elliott, Ravi Prakash Reddy Nanga, Sophia Swago, Walter R Witschey, Ravinder Reddy
PURPOSE: This goal of this study was to optimize spectrally selective 1 H MRS methods for large volume acquisition of low concentration metabolites with downfield resonances at 7T and 3T, with particular attention paid to detection of nicotinamide adenine dinucleotide (NAD + ) and tryptophan. METHODS: Spectrally selective excitation was used to avoid magnetization transfer effects with water, and various sinc pulses were compared to a pure-phase E-BURP pulse. Localization using a single slice selective pulse was compared to voxel-based localization that used three orthogonal refocusing pulses, and low bandwidth refocusing pulses were used to take advantage of the chemical shift displacement of water...
April 12, 2024: medRxiv
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JOURNAL ARTICLE
Ghada Dushaq, Solomon Serunjogi, Srinivasa R Tamalampudi, Mahmoud Rasras
Tunable optical materials are indispensable elements in modern optoelectronics, especially in integrated photonics circuits where precise control over the effective refractive index is essential for diverse applications. Two-dimensional materials like transition metal dichalcogenides (TMDs) and graphene exhibit remarkable optical responses to external stimuli. However, achieving distinctive modulation across short-wave infrared (SWIR) regions while enabling precise phase control at low signal loss within a compact footprint remains an ongoing challenge...
April 19, 2024: Light, Science & Applications
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JOURNAL ARTICLE
Jordan Wiebe, Nikhi P Singh, Steven Dawson, Jessica Berns, Connor Drake, Carla Fisher, Kandice Ludwig, R Jason VonDerHaar, Mary E Lester, Aladdin H Hassanein
BACKGROUND AND PURPOSE: Within, we compare the short-term outcomes of patients receiving same day mastectomy and tissue expander reconstruction for those discharged on postoperative day one versus those discharged immediately following surgery to explore the safety, efficacy, and potential impact on hospital processes. METHODS: This was a retrospective review of patients undergoing mastectomy with immediate TE reconstruction from March 2019 to March 2021. Patients were stratified into two cohorts; observation overnight (OBS), and discharge on same day of surgery (DC)...
April 12, 2024: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
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Thomas J Crotty, Gerard P Sexton, Fergal Kavanagh, John Kinsella, Paul Lennon, Conrad V Timon, Conall W R Fitzgerald
Tracheoesophageal puncture and voice prosthesis placement is the preferred method of voice restoration following total laryngectomy. Although this is a safe and effective means of optimizing voice, severe complications can occur. We present the case of a patient who developed cerebritis and ventriculitis secondary to a tracheoesophageal prosthesis eroding his cervical vertebrae 20 years following pharyngo-laryngo-esophagectomy. Despite optimal antimicrobial therapy, he deteriorated and succumbed to his disease...
April 2024: Journal of Surgical Case Reports
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JOURNAL ARTICLE
Bobby K Cheon, Meegan R Smith, Julia M P Bittner, Lucy K Loch, Hannah E Haynes, Bess F Bloomer, Jennifer A Te-Vazquez, Andrea I Bowling, Sheila M Brady, Marian Tanofsky-Kraff, Kong Y Chen, Jack A Yanovski
OBJECTIVES: Low social standing and teasing are independently associated with increased body mass index (BMI) and overeating in children. However, children with low social status may be vulnerable to teasing. METHODS: We tested the statistical interaction of subjective social status (SSS) and subjective socioeconomic status (SSES) and teasing distress on BMI, fat mass index (FMI), and eating in the absence of hunger (EAH) in children (Mage = 13.09 years, SD = 2...
April 18, 2024: Journal of Pediatric Psychology
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JOURNAL ARTICLE
Jean-David Larouche, Céline M Laumont, Assya Trofimov, Krystel Vincent, Leslie Hesnard, Sylvie Brochu, Caroline Côté, Juliette F Humeau, Éric Bonneil, Joel Lanoix, Chantal Durette, Patrick Gendron, Jean-Philippe Laverdure, Ellen R Richie, Sébastien Lemieux, Pierre Thibault, Claude Perreault
Transposable elements (TEs) are repetitive sequences representing ~45% of the human and mouse genomes and are highly expressed by medullary thymic epithelial cells (mTECs). In this study, we investigated the role of TEs on T-cell development in the thymus. We performed multiomic analyses of TEs in human and mouse thymic cells to elucidate their role in T-cell development. We report that TE expression in the human thymus is high and shows extensive age- and cell lineage-related variations. TE expression correlates with multiple transcription factors in all cell types of the human thymus...
April 18, 2024: ELife
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Mitch M Matoga, Evaristar Kudowa, Joachim Chikuni, Mercy Tsidya, Jennifer Tseka, Beatrice Ndalama, Naomi Bonongwe, Esther Mathiya, Edward Jere, Dumbo Yatina, Blessings Kamtambe, Martin Kapito, Mina C Hosseinipour, Charles S Chasela, Sara Jewett
INTRODUCTION: Uptake of voluntary medical male circumcision (VMMC) remains a challenge in many settings. Innovative implementation strategies are required to scale-up VMMC uptake. METHODOLOGY: RITe was a multi-faceted intervention comprising transport reimbursement (R), intensified health education (IHE) and SMS/Telephone tracing (Te), which increased the uptake of VMMC among uncircumcised men with sexually transmitted infections (STIs) in Malawi. Using a concurrent exploratory mixed-method approach, we assessed the intervention's acceptability, feasibility and appropriateness among men with STIs and healthcare workers (HCWs) at Bwaila District Hospital...
April 4, 2024: medRxiv
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JOURNAL ARTICLE
Saikat Santra, Prashant Singh
Resetting is a renewal mechanism in which a process is intermittently repeated after a random or fixed time. This simple act of stop and repeat profoundly influences the behavior of a system as exemplified by the emergence of nonequilibrium properties and expedition of search processes. Herein we explore the ramifications of stochastic resetting in the context of a single-file system called random average process (RAP) in one dimension. In particular, we focus on the dynamics of tracer particles and analytically compute the variance, equal time correlation, autocorrelation, and unequal time correlation between the positions of different tracer particles...
March 2024: Physical Review. E
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JOURNAL ARTICLE
Lana Mukharesh, Katie A Krone, Thomas E Hamilton, Hester F Shieh, Charles J Smithers, Zachary A Winthrop, Eleanor D Muise, Russell W Jennings, Somala Mohammed, Farokh R Demehri, Benjamin Zendejas, Gary A Visner
BACKGROUND: Tracheobronchomalacia (TBM) is characterized by excessive dynamic airway collapse. Severe TBM can be associated with substantial morbidity. Children with secondary TBM associated with esophageal atresia/tracheoesophageal fistula (EA/TEF) and vascular-related airway compression (VRAC) demonstrate clinical improvement following airway pexy surgery. It is unclear if children with severe primary TBM, without secondary etiologies (EA/TEF, vascular ring, intrinsic pulmonary pathology, or complex cardiac disease) demonstrate clinical improvement following airway pexy surgery...
April 17, 2024: Pediatric Pulmonology
#17
JOURNAL ARTICLE
Haoyao Liu, Osman Tuncay Agar, Ali Imran, Colin J Barrow, Frank R Dunshea, Hafiz A R Suleria
Passion fruits, renowned globally for their polyphenolic content and associated health benefits, have enjoyed growing attention from consumers and producers alike. While global cultivar development progresses, Australia has pioneered several native cultivars tailored for its distinct planting conditions. Despite their cultivation, comprehensive studies on the phenolic profiles and antioxidant capacities of these Australian-native passion fruits are notably lacking. This study aims to investigate and compare the polyphenolic content present in the by-products, which are peel (L), and consumable portions, which are the pulp and seeds (P), of four indigenous cultivars: 'Misty Gem' (MG), 'Flamengo' (FG), 'Sweetheart' (SW), and 'Panama' (SH)...
April 2024: Food Science & Nutrition
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JOURNAL ARTICLE
Yasmeen M Bashmil, Frank R Dunshea, Rudi Appels, Hafiz A R Suleria
Green bananas contain a substantial amount of resistant starch (RS), dietary fiber (DF), and phytochemicals, which exhibit potent antioxidant capabilities, primarily attributable to the abundance of polyphenols. The objective of this study was to assess the variations in the contents and bioaccessibility of RS, DF, and phenolic compounds in three types of Australian green bananas (Cavendish " Musa acuminata ", Ladyfinger " Musa paradisiaca L.", and Ducasse " Musa balbisiana "), along with their antioxidant capacities, and the production of short-chain fatty acids (SCFAs) following in vitro simulated gastrointestinal digestion and colonic fermentation...
March 29, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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JOURNAL ARTICLE
H Naik, R J Singh, S P Dange, W Jang
Studies on charge distribution have been carried out in the epi-cadmium neutron induced fission of 238 Pu for the first time. Experimentally fractional cumulative yields (FCY) and independent yields (IY) of various fission products have been measured by using an off-line γ-ray spectrometric technique. From the FCY values, the charge distribution parameters such as the isobaric width parameter (σZ ), most probable charge (ZP ) and the charge polarization (ΔΖEXPT ) as a function of fragment mass were obtained...
April 7, 2024: Applied Radiation and Isotopes
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JOURNAL ARTICLE
Rigele Te, Bo Zhu, Haobo Ma, Xiuhua Zhang, Shaohui Chen, Yuguang Huang, Geqi Qi
BACKGROUND: Adequate preoperative evaluation of the post-intubation hemodynamic instability (PIHI) is crucial for accurate risk assessment and efficient anesthesia management. However, the incorporation of this evaluation within a predictive framework have been insufficiently addressed and executed. This study aims to developed a machine learning approach for preoperatively and precisely predicting the PIHI index values. METHODS: In this retrospective study, the valid features were collected from 23,305 adult surgical patients at Peking Union Medical College Hospital between 2012 and 2020...
April 9, 2024: BMC Anesthesiology
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