keyword
MENU ▼
Read by QxMD icon Read
search

balanced

keyword
https://www.readbyqxmd.com/read/28445875/double-incision-approach-and-early-rehabilitation-in-a-complicated-bicondylar-br-tibial-plateau-fracture-a-case-report-br-br
#1
Saverio Affatato, Maurizio Montalti, Claudio Masetti, Federico Giardina, Alessandra Sudanese
OBJECTIVE: The main goal of this case was to report the treatment of bicondylar fractures of the tibial plateau and the restoration of the metaphyseo-diaphyseal dissociation. CLINICAL PRESENTATION AND INTERVENTION: A 54-year old man who was cycling had a road accident that caused a closed fracture of the right tibial plateau and proximal fibula diagnosed by x-rays. Patient had surgical procedure and was immobilized with a long-leg splint for 4 weeks. After immobilization, aggressive rehabilitation was done...
April 26, 2017: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/28445854/balance-training-in-individuals-with-parkinson-s-disease-therapist-supervised-vs-home-based-exercise-programme
#2
Elizabeth Maria Atterbury, Karen Estelle Welman
BACKGROUND: Poor locomotion and balance in Parkinson's disease (PD) often diminishes independence. Accordingly, gait is considered one of the most relevant rehabilitation outcomes, and home-based balance exercises might be a viable mode of exercise delivery for individuals with PD. However, research on PD interventions rarely indicate best practices to deliver exercises. Therefore, this study endeavoured to compare the efficacy of a home-based and therapist-supervised balance programme on gait parameters, dynamic balance, balance confidence and motivation in individuals diagnosed with PD...
April 4, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28445828/targeting-the-aryl-hydrocarbon-receptor-nuclear-translocator-complex-with-dmog-and-stemregenin-1-improves-primitive-hematopoietic-stem-cell-expansion
#3
Carlo Stephan Jackson, Chrisna Durandt, Ilse Janse van Rensburg, Vincent Praloran, Philippe Brunet de la Grange, Michael Sean Pepper
Culture conditions used for the expansion of hematopoietic stem and progenitor cells (HSCs and HPCs, collectively HSPCs) should ideally favor the self renewal of long-term HSCs. At 20% O2, the synthesis of HIF-1α is balanced by its hydroxylation and proteasomal degradation. This favors HSPC differentiation, but can be prevented by culturing CD34+ cord blood cells in the presence of dimethyloxaloylglycine (DMOG). This differentiation may also be reduced by culturing the cells in the presence of Stemregenin 1, an antagonist of the aryl hydrocarbon receptor (AhR)...
April 20, 2017: Stem Cell Research
https://www.readbyqxmd.com/read/28445732/the-hect-family-ubiquitin-ligase-eel-1-regulates-neuronal-function-and-development
#4
Karla J Opperman, Ben Mulcahy, Andrew C Giles, Monica G Risley, Rayna L Birnbaum, Erik D Tulgren, Ken Dawson-Scully, Mei Zhen, Brock Grill
Genetic changes in the HECT ubiquitin ligase HUWE1 are associated with intellectual disability, but it remains unknown whether HUWE1 functions in post-mitotic neurons to affect circuit function. Using genetics, pharmacology, and electrophysiology, we show that EEL-1, the HUWE1 ortholog in C. elegans, preferentially regulates GABAergic presynaptic transmission. Decreasing or increasing EEL-1 function alters GABAergic transmission and the excitatory/inhibitory (E/I) balance in the worm motor circuit, which leads to impaired locomotion and increased sensitivity to electroshock...
April 25, 2017: Cell Reports
https://www.readbyqxmd.com/read/28445712/consider-the-context-ras-erk-and-pi3k-akt-mtor-signaling-outcomes-are-pituitary-cell-type-specific
#5
REVIEW
Allyson K Roof, Arthur Gutierrez-Hartmann
Conserved signaling pathways are critical regulators of pituitary homeostasis and, when dysregulated, contribute to adenoma formation. Pituitary adenomas are typically benign and rarely progress to malignant cancer. Pituitary and other neuroendocrine cell types often display non-proliferative responses to ERK and PI3K, in contrast to non-endocrine cell types which typically proliferate in response to ERK and PI3K activation. These differences likely contribute to the infrequent progression to malignancy in many endocrine tumors...
April 23, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28445699/journey-of-cystatins-from-being-mere-thiol-protease-inhibitors-to-at-heart-of-many-pathological-conditions
#6
REVIEW
Anas Shamsi, Bilqees Bano
Cystatins are thiol proteinase inhibitors (TPI), present ubiquitously in animals, plants and micro-organisms. These are not merely inhibitors rather they are at heart of many pathological conditions ranging from diabetes to renal failure. These are essential for maintenance of protein balance of the cell; once this balance gets disturbed, it may lead to cell death. Thus, cystatins cannot be merely regarded as TPI's as these have been found to play a pivotal role in tumorigenesis and neurodegenerative diseases...
April 23, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28445586/predictors-of-outcome-among-patients-on-extracorporeal-membrane-oxygenation-as-a-bridge-to-lung-transplantation
#7
Amit Banga, Elizabeth Batchelor, Manish Mohanka, Srinivas Bollineni, Vaidehi Kaza, Jessica Mullins, Melissa Tran, Pietro Bajona, Matthias Peltz, Michael Wait, Fernando Torres
BACKGROUND: There is a lack of data regarding clinical variables associated with successful bridge to lung transplantation (LT) using extracorporeal membrane oxygenation (ECMO) support. METHODS: We reviewed the institutional database for patients supported with veno-venous (VV) or veno-arterial ECMO as a bridge to LT (n=25; mean age:50.6±14.2 years). We recorded clinical and laboratory variables, findings on echocardiogram and development of organ dysfunction along with hospital and one-year survival...
April 26, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/28445568/balancing-motherhood-career-and-medicine
#8
Ure Mezu-Chukwu
No abstract text is available yet for this article.
April 26, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28445533/influence-of-temperature-on-daily-locomotor-activity-in-the-crab-uca-pugilator
#9
Audrey M Mat, Gideon P Dunster, Valerio Sbragaglia, Jacopo Aguzzi, Horacio O de la Iglesia
Animals living in the intertidal zone are exposed to prominent temperature changes. To cope with the energetic demands of environmental thermal challenges, ectotherms rely mainly on behavioral responses, which may change depending on the time of the day and seasonally. Here, we analyze how temperature shapes crabs' behavior at 2 different times of the year and show that a transition from constant cold (13.5°C) to constant warm (17.5°C) water temperature leads to increased locomotor activity levels throughout the day in fiddler crabs (Uca pugilator) collected during the summer...
2017: PloS One
https://www.readbyqxmd.com/read/28445434/an-adaptive-clustering-approach-based-on-minimum-travel-route-planning-for-wireless-sensor-networks-with-a-mobile-sink
#10
Jiqiang Tang, Wu Yang, Lingyun Zhu, Dong Wang, Xin Feng
In recent years, Wireless Sensor Networks with a Mobile Sink (WSN-MS) have been an active research topic due to the widespread use of mobile devices. However, how to get the balance between data delivery latency and energy consumption becomes a key issue of WSN-MS. In this paper, we study the clustering approach by jointly considering the Route planning for mobile sink and Clustering Problem (RCP) for static sensor nodes. We solve the RCP problem by using the minimum travel route clustering approach, which applies the minimum travel route of the mobile sink to guide the clustering process...
April 26, 2017: Sensors
https://www.readbyqxmd.com/read/28445373/auricular-reconstruction-in-hemifacial-microsomia-with-an-expanded-two-flap-method
#11
Jin Qian, Zhibin Li, Tun Liu, Xu Zhou, Qingguo Zhang
BACKGROUND: Reconstruction of external ear is important for the child/adult with craniofacial deformities to achieve balance and harmony of the face and head. The aim of this study was to investigate the clinical application of an expanded two-flap method for auricular reconstruction in hemifacial microsomia. METHODS: Between January of 2014 and November of 2015, 111 hemifacial microsomia patients with microtia underwent auricular reconstruction with an expanded two-flap method...
May 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28445225/physical-fitness-and-body-composition-in-8-10-year-old-danish-children-are-associated-with-sports-club-participation
#12
Malte N Larsen, Claus M Nielsen, Christina Ørntoft, Morten Br Thomsen, Vibeke Manniche, Lone Hansen, Peter R Hansen, Jens Bangsbo, Peter Krustrup
We investigated whether physical fitness and body composition in 8-10-year-old Danish children are associated with sports club participation. The study included 423 schoolchildren, comprising 209 girls and 214 boys, of whom 67 and 74%, respectively, were active in sports clubs. Yo-Yo Intermittent Recovery level 1 for Children (YYIR1C), balance, jump and coordination tests, together with DXA scans, were used to determine exercise capacity and body composition. Children active in sports clubs had better (P<0...
April 18, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28445221/changes-in-personal-relationships-during-residency-and-their-effects-on-resident-wellness-a-qualitative-study
#13
Marcus Law, Michelle Lam, Diana Wu, Paula Veinot, Maria Mylopoulos
PURPOSE: Residency poses challenges for residents' personal relationships. Research suggests residents rely on family and friends for support during their training. The authors explored the impact of residency demands on residents' personal relationships and the effects changes in those relationships could have on their wellness. METHOD: The authors used a constructivist grounded theory approach. In 2012-2014, they conducted semistructured interviews with a purposive and theoretical sample of 16 Canadian residents from various specialties and training levels...
April 25, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28445213/learner-patient-and-supervisor-features-are-associated-with-different-types-of-cognitive-load-during-procedural-skills-training-implications-for-teaching-and-instructional-design
#14
Justin L Sewell, Christy K Boscardin, John Q Young, Olle Ten Cate, Patricia S O'Sullivan
PURPOSE: Cognitive load theory, focusing on limits of the working memory, is relevant to medical education; however, factors associated with cognitive load during procedural skills training are not well characterized. The authors sought to determine how features of learners, patients/tasks, settings, and supervisors were associated with three types of cognitive load among learners performing a specific procedure, colonoscopy, to identify implications for procedural teaching. METHOD: Data were collected through an electronically administered survey sent to 1,061 U...
April 25, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28445172/telehealth-intensive-care-unit-nurse-surveillance-of-sepsis
#15
Teresa A Rincon, E LaVerne Manos, Janet D Pierce
The purpose of this article is to describe the usability and human factors engineering standards used in development of a sepsis alert known as the sepsis prompt. Sensory processing, cognitive processing, signal detection, criterion response, and user satisfaction were evaluated with controlled user testing and critical incident response techniques. Nurses reported that the sepsis prompt was visible and distinct, making it easily detectable. The prompt provided a clear response mechanism and adequately balanced the number of false alerts with the likelihood of misses...
April 25, 2017: Computers, Informatics, Nursing: CIN
https://www.readbyqxmd.com/read/28445071/polymorphic-assembly-from-beveled-gold-triangular-nanoprisms
#16
Juyeong Kim, Xiaohui Song, Fei Ji, Binbin Luo, Nicole F Ice, Qipeng Liu, Qiao Zhang, Qian Chen
The shape anisotropy of nanoparticle building blocks is of critical importance in determining their packing symmetry and assembly directionality. While there has been extensive research on the effect of their overall geometric shapes, the importance of nanometer morphology details is not well-recognized or understood. Here we draw on shape-anisotropic gold triangular nanoprism building blocks synthesized based on a method we recently developed; besides the "large-scale" triangular prism shape (79.8 nm in side length and 22...
April 26, 2017: Nano Letters
https://www.readbyqxmd.com/read/28444869/assessment-of-the-usage-of-biodegradable-polymeric-matrix-in-vaginal-devices-to-sustain-progesterone-release-in-cows
#17
José Rodrigo Valim Pimentel, Milton Maturana Filho, Lucio Cardozo-Filho, José Augusto M Agnelli, Jefter Nascimento, Ed Hoffmann Madureira
The usage of timed artificial insemination (TAI) at a low cost leading to better reproductive rates has been the aim of several research groups in the field. Usually during TAI protocols, sustained progesterone (P4 ) release devices are employed. Most devices are constituted of a nylon skeleton covered with a silicon layer with P4 . A device based on biopolymers was developed in order to reduce costs and decrease its environmental impact. In this study, we compared the kinetics of sustained progesterone release among devices manufactured with a polymeric blend made of polyhydroxybutyrate-valerate (PHBV) and poly-ε-caprolactone (PCL) (DISP) which were compared with DIB® (Internal Bovine Device) used as the control...
April 25, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/28444680/-disability-after-stroke-a-longitudinal-study-in-moderate-and-severe-stroke-patients-included-in-a-multidisciplinary-rehabilitation-program
#18
E Noe-Sebastian, M Balasch-Bernat, C Colomer-Font, B Moliner-Munoz, C Rodriguez Sanchez-Leiva, P Ugart, R Llorens, J Ferri-Campos
INTRODUCTION: Stroke is a recognized cause of disability among adults. However the impact that the deficits that occur after a moderate/severe stroke have on long-term disability, as well as the response of the resultant deficits to rehabilitation, are not completely understood. PATIENTS AND METHODS: A total of 396 patients with a modified Rankin score >= 3 after an ischemic (n = 221) or hemorrhagic (n = 175) stroke were included in this study. All patients were assessed with cognitive, behavior, emotional, motor and functional domains...
May 1, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28444664/endocrine-complications-of-surgical-treatment-of-thyroid-cancer-an-update
#19
Pedro Iglesias, Juan José Díez
Postoperative hypoparathyroidism (HypoPT) and hypothyroidism (HypoT) are the main endocrine complications after the surgical treatment for thyroid cancer. Postsurgical HypoPT can be transient, protracted or permanent. Its frequency varies according to the underlying cervical pathology, surgical technique, and mainly the experience of the surgeon. Risk factors for HypoPT include aggressiveness of the tumor, extent of surgery, the presence of parathyroid gland in the pathologic specimen, and surgeon experience...
April 25, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/28444510/starvation-signals-in-yeast-are-integrated-to-coordinate-metabolic-reprogramming-and-stress-response-to-ensure-longevity
#20
REVIEW
Nianshu Zhang, Lu Cao
Studies on replicative and chronological aging in Saccharomyces cerevisiae have greatly advanced our understanding of how longevity is regulated in all eukaryotes. Chronological lifespan (CLS) of yeast is defined as the age-dependent viability of non-dividing cell populations. A number of nutrient sensing and signal transduction pathways (mainly TOR and PKA) have been shown to regulate CLS, yet it is poorly understood how the starvation signals transduced via these pathways lead to CLS extension. Using reporters whose expressions are induced by glucose starvation, we have screened the majority of the 'signaling' mutants in the yeast genome and identified many genes that are necessary for stress response...
April 25, 2017: Current Genetics
keyword
keyword
50730
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"