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https://www.readbyqxmd.com/read/28284488/agnosic-vision-is-like-peripheral-vision-which-is-limited-by-crowding
#1
Francesca Strappini, Denis G Pelli, Enrico Di Pace, Marialuisa Martelli
Visual agnosia is a neuropsychological impairment of visual object recognition despite near-normal acuity and visual fields. A century of research has provided only a rudimentary account of the functional damage underlying this deficit. We find that the object-recognition ability of agnosic patients viewing an object directly is like that of normally-sighted observers viewing it indirectly, with peripheral vision. Thus, agnosic vision is like peripheral vision. We obtained 14 visual-object-recognition tests that are commonly used for diagnosis of visual agnosia...
February 1, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28258660/pure-optic-ataxia-and-visual-hemiagnosia-extending-the-dual-visual-hypothesis
#2
Jurka R Meichtry, Dario Cazzoli, Silvia Chaves, Sebastian von Arx, Tobias Pflugshaupt, Roger Kalla, Claudio L Bassetti, Klemens Gutbrod, René M Müri
Goodale and Milner's two visual system hypothesis is an influential model for the understanding of the primate visual system. Lesions of either the ventral (occipito-temporal) or the dorsal (occipito-parietal) stream produce distinct and dissociated syndromes in humans: visual agnosia is typical for ventral damage, whereas optic ataxia (OA) for dorsal damage. We studied the case of a 59-year-old left-handed woman with a circumscribed lesion around the left posterior occipital sulcus, extending to the underlying white matter...
March 4, 2017: Journal of Neuropsychology
https://www.readbyqxmd.com/read/28255843/how-do-the-two-visual-streams-interact-with-each-other
#3
REVIEW
A D Milner
The current consensus divides primate cortical visual processing into two broad networks or "streams" composed of highly interconnected areas (Milner and Goodale 2006, 2008; Goodale 2014). The ventral stream, passing from primary visual cortex (V1) through to inferior parts of the temporal lobe, is considered to mediate the transformation of the contents of the visual signal into the mental furniture that guides memory, recognition and conscious perception. In contrast the dorsal stream, passing from V1 through to various areas in the posterior parietal lobe, is generally considered to mediate the visual guidance of action, primarily in real time...
March 2, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28254833/yellow-fever-vaccine-associated-neurological-disease-a-suspicious-case
#4
Pedro Beirão, Patrícia Pereira, Andreia Nunes, Pedro Antunes
A 70-year-old man with known cardiovascular risk factors, presented with acute onset expression aphasia, agraphia, dyscalculia, right-left disorientation and finger agnosia, without fever or meningeal signs. Stroke was thought to be the cause, but cerebrovascular disease investigation was negative. Interviewing the family revealed he had undergone yellow fever vaccination 18 days before. Lumbar puncture revealed mild protein elevation. Cultural examinations, Coxiella burnetti, and neurotropic virus serologies were negative...
March 2, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28223685/finger-posture-modulates-structural-body-representations
#5
Luigi Tamè, Elanah Dransfield, Thomas Quettier, Matthew R Longo
Patients with lesions of the left posterior parietal cortex commonly fail in identifying their fingers, a condition known as finger agnosia, yet are relatively unimpaired in sensation and skilled action. Such dissociations have traditionally been interpreted as evidence that structural body representations (BSR), such as the body structural description, are distinct from sensorimotor representations, such as the body schema. We investigated whether performance on tasks commonly used to assess finger agnosia is modulated by changes in hand posture...
February 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28180083/lateralized-occipital-degeneration-in-posterior-cortical-atrophy-predicts-visual-field-deficits
#6
Rebecca S Millington, Merle James-Galton, Mari N Maia Da Silva, Gordon T Plant, Holly Bridge
BACKGROUND: Posterior cortical atrophy (PCA), the visual variant of Alzheimer's disease, leads to high-level visual deficits such as alexia or agnosia. Visual field deficits have also been identified, but often inconsistently reported. Little is known about the pattern of visual field deficits or the underlying cortical changes leading to this visual loss. METHODS: Multi-modal magnetic resonance imaging was used to investigate differences in gray matter volume, cortical thickness, white matter microstructure and functional activity in patients with PCA compared to age-matched controls...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28164221/landmark-agnosia-evaluating-the-definition-of-landmark-based-navigation-impairment
#7
Ineke J M van der Ham, Marieke A G Martens, Michiel H G Claessen, Esther van den Berg
No abstract text is available yet for this article.
February 6, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/27956263/functional-modulation-of-contralateral-bias-in-early-and-object-selective-areas-after-stroke-of-the-occipital-ventral-cortices
#8
Maren Praß, Cathleen Grimsen, Manfred Fahle
Object agnosia is a rare symptom, occurring mainly after bilateral damage of the ventral visual cortex. Most patients suffering from unilateral ventral lesions are clinically non-agnosic. Here, we studied the effect of unilateral occipito-temporal lesions on object categorization and its underlying neural correlates in visual areas. Thirteen non-agnosic stroke patients and twelve control subjects performed an event-related rapid object categorization task in the fMRI scanner where images were presented either to the left or to the right of a fixed point...
December 9, 2016: Neuropsychologia
https://www.readbyqxmd.com/read/27903133/emotional-quotient-in-frontotemporal-dementia-vs-alzheimer-s-disease-the-role-of-socioemotional-agnosia
#9
Andrew R Carr, Mersal S Samimi, Pongsatorn Paholpak, Elvira E Jimenez, Mario F Mendez
INTRODUCTION: Socioemotional dysfunction distinguishes behavioural variant frontotemporal dementia (bvFTD) from other dementias. Patients with bvFTD not only have early social impairment and emotional blunting, but they also have agnosia of their socioemotional dysfunction. METHODS: To investigate the relationship between agnosia and dysfunction, we assessed self-knowledge of socioemotional dysfunction with an emotional quotient (EQ) scale administered to 12 patients with bvFTD and a comparison group of 12 age-matched patients with Alzheimer's disease (AD), and compared these self-ratings to caregiver ratings of social dysfunction and emotional blunting...
November 30, 2016: Cognitive Neuropsychiatry
https://www.readbyqxmd.com/read/27863703/reprint-of-object-based-attentional-facilitation-and-inhibition-are-neuropsychologically-dissociated
#10
Daniel T Smith, Keira Ball, Robert Swalwell, Thomas Schenk
Salient peripheral cues produce a transient shift of attention which is superseded by a sustained inhibitory effect. Cueing part of an object produces an inhibitory cueing effect (ICE) that spreads throughout the object. In dynamic scenes the ICE stays with objects as they move. We examined object-centred attentional facilitation and inhibition in a patient with visual form agnosia. There was no evidence of object-centred attentional facilitation. In contrast, object-centred ICE was observed in 3 out of 4 tasks...
November 15, 2016: Neuropsychologia
https://www.readbyqxmd.com/read/27821572/pearls-oy-sters-visual-agnosia-an-overlooked-cortical-sign
#11
Bruno Bergmans, Olivier Deryck, Rose Bruffaerts
No abstract text is available yet for this article.
November 8, 2016: Neurology
https://www.readbyqxmd.com/read/27777020/neurological-manifestations-of-autosomal-dominant-familial-alzheimer-s-disease-a-comparison-of-the-published-literature-with-the-dominantly-inherited-alzheimer-network-observational-study-dian-obs
#12
Mengxuan Tang, Davis C Ryman, Eric McDade, Mateusz S Jasielec, Virginia D Buckles, Nigel J Cairns, Anne M Fagan, Alison Goate, Daniel S Marcus, Chengjie Xiong, Ricardo F Allegri, Jasmeer P Chhatwal, Adrian Danek, Martin R Farlow, Nick C Fox, Bernardino Ghetti, Neill R Graff-Radford, Christopher Laske, Ralph N Martins, Colin L Masters, Richard P Mayeux, John M Ringman, Martin N Rossor, Stephen P Salloway, Peter R Schofield, John C Morris, Randall J Bateman
BACKGROUND: Autosomal dominant familial Alzheimer's disease (ADAD) is a rare disorder with non-amnestic neurological symptoms in some clinical presentations. We aimed to compile and compare data from symptomatic participants in the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS) with those reported in the literature to estimate the prevalences of non-amnestic neurological symptoms in participants with ADAD. METHODS: We prospectively collected data from the DIAN-OBS database, which recruited participants from study centres in the USA, Europe, and Australia, between Feb 29, 2008, and July 1, 2014...
December 2016: Lancet Neurology
https://www.readbyqxmd.com/read/27720525/predictive-value-of-modifications-of-the-prehospital-rapid-arterial-occlusion-evaluation-scale-for-large-vessel-occlusion-in-patients-with-acute-stroke
#13
David Carrera, Bruce C V Campbell, Jordi Cortés, Montse Gorchs, Marisol Querol, Xavier Jiménez, Mònica Millán, Antoni Dávalos, Natalia Pérez de la Ossa
BACKGROUND: Prehospital clinical scales to identify patients with acute stroke with a large vessel occlusion (LVO) and direct them to an endovascular-capable stroke center are needed. We evaluated whether simplification of the Rapid Arterial oCclusion Evaluation (RACE) scale, a 5-item scale previously validated in the field, could maintain its high performance to identify patients with LVO. METHODS: Using the original prospective validation cohort of the RACE scale, 7 simpler versions of the RACE scale were designed and retrospectively recalculated for each patient...
January 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27677897/impaired-velocity-processing-reveals-an-agnosia-for-motion-in-depth
#14
Martijn Barendregt, Serge O Dumoulin, Bas Rokers
Many individuals with normal visual acuity are unable to discriminate the direction of 3-D motion in a portion of their visual field, a deficit previously referred to as a stereomotion scotoma. The origin of this visual deficit has remained unclear. We hypothesized that the impairment is due to a failure in the processing of one of the two binocular cues to motion in depth: changes in binocular disparity over time or interocular velocity differences. We isolated the contributions of these two cues and found that sensitivity to interocular velocity differences, but not changes in binocular disparity, varied systematically with observers' ability to judge motion direction...
September 27, 2016: Psychological Science
https://www.readbyqxmd.com/read/27672976/poster-215-gustatory-agnosia-following-herpes-simplex-virus-encephalitis-a-case-report
#15
Shannon Schultz, Lori Grafton, David R Gater
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27649025/cognitive-world-neuropsychology-of-individual-differences
#16
Alfredo Ardila, Monica Rosselli
It is proposed that depending upon the specific pattern of cognitive abilities, each individual lives in an idiosyncratic "cognitive world." Brain pathology can be associated with some disturbed abilities, and frequently experiential changes (i.e., how the world is understood) are observed. Because these patients often are aware of their intellectual changes, they may represent excellent models to illustrate the diversity of cognitive interpretations an individual can have about the surrounding environmental conditions...
September 20, 2016: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/27530874/partial-kluver-bucy-syndrome-secondary-to-tubercular-meningitis
#17
Kunal Kishor Jha, Satyajeet Kumar Singh, Prem Kumar, Charu Dutt Arora
Tubercular meningitis (TBM) is a devastating extra pulmonary manifestation of tuberculosis and demonstrates a high neurological morbidity. A rare complication of this condition is Kluver-Bucy syndrome (KBS), which is a neurobehavioral disorder characterised by hyper-sexuality, visual agnosia, bulimia, placidity, hyperorality and memory deficits caused by lesions to the amygdala. The amygdala lesions can be due to many causes, including traumatic brain injury, systemic conditions and infections such as tuberculosis...
August 16, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27516006/molecular-mechanisms-underlying-neurodevelopmental-disorders-adhd-and-autism
#18
George Mihai Bădescu, Mădălina Fîlfan, Raluca Elena Sandu, Roxana Surugiu, Ovidiu Ciobanu, Aurel Popa-Wagner
Neurodevelopmental disorders such as attention deficit hyperactivity disorder and autism represent a significant economic burden, which justify vigorous research to uncover its genetics and developmental clinics for a diagnostic workup. The urgency of addressing attention deficit hyperactivity disorder comorbidities is seen in the chilling fact that attention deficit hyperactivity disorder (ADHD), mood disorders, substance use disorders and obesity each increase the risk for mortality. However, data about comorbidity is mainly descriptive, with mechanistic studies limited to genetic epidemiological studies that document shared genetic risk factors among these conditions...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27432262/neurological-soft-signs-in-chinese-adolescents-with-schizophrenia-and-schizotypal-personality-traits
#19
Xin Wang, Lin Cai, Lingyan Li, Yanjie Yang, Xiongzhao Zhu
OBJECTIVE: Neurological soft signs (NSSs) may reflect neurodevelopmental anomalies in association with the spectrum of schizophrenia disorders. We examined NSSs in Chinese adolescents with schizophrenia and schizotypal personality traits. METHODS: Eighty-seven schizophrenic adolescents (SCH group), 85 adolescents with only schizotypal personality traits (SPT group), and 88 healthy controls (HC group) were enrolled. The NSS subscales of the Cambridge Neurological Inventory (CNI) were administered to all 260 participants...
October 2016: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/27423559/can-patients-without-early-prominent-visual-deficits-still-be-diagnosed-of-posterior-cortical-atrophy
#20
A Suárez-González, S J Crutch, F Roldán Lora, E Franco-Macías, E Gil-Néciga
BACKGROUND: Early and progressive disabling visual impairment is a core feature for the diagnosis of posterior cortical atrophy (PCA). However, some individuals that fulfil criteria over time might initially present with an onset of prominent posterior dysfunction other than visuoperceptual. METHODS: The clinical profile of five patients with a predominantly 'non-visual' posterior presentation (PCA2) was investigated and compared with sixteen individuals with visually predominant PCA (PCA1) and eighteen with typical amnestic Alzheimer disease (tAD)...
August 15, 2016: Journal of the Neurological Sciences
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