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https://www.readbyqxmd.com/read/29161472/a-young-child-with-fever-alopecia-and-skin-nodules-a-clinicopathological-conference
#1
Pandiarajan Vignesh, Aman Gupta, Deepti Suri, Debajyoti Chatterjee, Uma Nahar Saikia, Amita Trehan, Surjit Singh
The illness started as a continuous high-grade fever noted up to 103°F.. Subsequently, he also developed red painful skin nodules that initially appeared over shins and later progressed to involve thighs, trunks, upper extremities, and face. The nodules also appeared over scalp and there was a was a progressive loss of scalp hair. This article is protected by copyright. All rights reserved.
November 21, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29152297/sudden-swelling-and-redness-of-the-toe
#2
Vera Tengattini, Michela Magnano, Annalisa Patrizi, Iria Neri
The presence of history of redness and swelling of toe in an infant without history of trauma is typical of hair threat tourniquet syndrome. The treatment simply involves incision and removal of hair fibers. Physicians should be aware of this syndrome because early diagnosis and treatment avoid serious complications.
November 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/29124788/need-for-multiscale-planning-for-conservation-of-urban-bats
#3
Travis Gallo, Elizabeth W Lehrer, Mason Fidino, R Julia Kilgour, Patrick J Wolff, Seth Magle
For over a century there have been continual efforts to incorporate nature into urban planning. These efforts - known as urban reconciliation- aim to manage and create habitats that support biodiversity within cities. Given that species select habitat at different spatial scales, understanding the scale at which urban species respond to their environment is critical to the success of urban reconciliation efforts. We assessed species-habitat relationships for common bat species at local (50-m), medium (500-m), and broad (1-km) spatial scales in the Chicago metropolitan area and predicted bat activity across the greater Chicago region...
November 10, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/29110673/clinical-outcomes-of-graves-ophthalmopathy-treated-with-intensity-modulated-radiation-therapy
#4
Yong-Jiang Li, Yong Luo, Wei-Min He, Ping Li, Feng Wang
BACKGROUND: Radiation for Graves' ophthalmopathy (GO) has traditionally utilized lateral opposing fields (LOF) or three-dimensional conformal radiotherapy (3DCRT) technique. The current study was conducted to report clinical outcomes and therapeutic effects of intensity modulated radiation therapy (IMRT) in treating GO patients. METHODS: One hundred sixteen patients with GO were treated with IMRT as initial local therapy between July 2010 and August 2013, with a median follow-up of 62 months (range 45-81 months)...
November 6, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/29081812/peptide-inhibitor-of-complement-c1-inhibits-the-peroxidase-activity-of-hemoglobin-and-myoglobin
#5
Pamela S Hair, Kenji M Cunnion, Neel K Krishna
Hemoglobin is the natural carrier of oxygen in red blood cells (RBCs). While intracellular hemoglobin provides life-sustaining oxygen transport, extracellular free hemoglobin displays toxicity due to inherent peroxidase activity generating reactive oxygen species that subsequently react with the hemoglobin molecule to produce toxic heme degradation products resulting in free radicals, oxidative stress damage, and lipid peroxidation. We have recently demonstrated that Peptide Inhibitor of Complement C1 (PIC1) inhibits peroxidase activity of the heme-based enzyme myeloperoxidase...
2017: International Journal of Peptides
https://www.readbyqxmd.com/read/29062845/efficacy-of-aloevera-cream-in-the-treatment-of-paederus-dermatitis-in-mice
#6
Ramin Khaghani, Iraj Mirzaii-Dizgah, Mostafa Ghasemi
BACKGROUND: Dermatitis caused by Paederus beetle involves many people around the world, especially Iran. The symptoms include redness, itching and severe irritation. This study evaluated the effectiveness of the Aloevera cream on the treatment of dermatitis caused by Paederus beetles. METHODS: Forty male 6-8 weeks BALB/C mice were randomly divided into four groups of 10 mice. After removing the mice's back hair, the backs of mice were marked by a circle with a diameter of 3 mm...
June 2017: Journal of Arthropod-borne Diseases
https://www.readbyqxmd.com/read/29048992/eurasian-red-squirrels-show-little-seasonal-variation-in-metabolism-in-food-enriched-habitat
#7
James M Turner, Stephanie Reher, Lisa Warnecke, Kathrin H Dausmann
Energy expenditure and ambient temperature (Ta) are intrinsically linked through changes in an animal's metabolic rate. While the nature of this relationship is stable, the breadth of change in thermoregulatory cost varies with body size and physiological acclimatization to season. To explore seasonal metabolic changes of small mammals, we studied a population of Eurasian red squirrels (Sciurus vulgaris) in a seminatural environment with a year-round supply of natural and supplemented food. In each season we measured the metabolic rate of wild-caught red squirrels, using open-flow respirometry, and hypothesized that individuals would make adjustments to contend with seasonal weather conditions...
November 2017: Physiological and Biochemical Zoology: PBZ
https://www.readbyqxmd.com/read/29037406/monitoring-changes-in-body-surface-temperature-associated-with-treadmill-exercise-in-dogs-by-use-of-infrared-methodology
#8
Maria Rizzo, Francesca Arfuso, Daniela Alberghina, Elisabetta Giudice, Matteo Gianesella, Giuseppe Piccione
The aim of this study was to evaluate the influence of moderate treadmill exercise session on body surface and core temperature in dog measured by means of two infrared instruments. Ten Jack Russell Terrier/Miniature Pinscher mixed-breed dogs were subjected to 15min of walking, 10min of trotting and 10min of gallop. At every step, body surface temperature (Tsurface) was measured on seven regions (neck, shoulder, ribs, flank, back, internal thigh and eye) using two different methods, a digital infrared camera (ThermaCam P25) and a non-contact infrared thermometer (Infrared Thermometer THM010-VT001)...
October 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/29037398/thermoregulation-of-male-sheep-of-indigenous-or-exotic-breeds-in-a-tropical-environment
#9
Messy Hannear de Andrade Pantoja, Sérgio Novita Esteves, Manuel Antonio Chagas Jacinto, José Ricardo Macedo Pezzopane, Cláudia Cristina Paro de Paz, Jamile Andréa Rodrigues da Silva, José de Brito Lourenço Junior, Felipe Zandonadi Brandão, Ana Beatriz Bossois Moura, Narian Romanello, Daniela Botta, Alexandre Rossetto Garcia
Climate change has intensified the frequency of heat waves in the world, thereby exposing farm animals to stressful conditions. For better productive performance it is important to identify the most resilient genotypes. Thus, our objective was to evaluate the thermoregulatory responses of rams of tropical indigenous (Morada Nova and Santa Inês) and exotic breeds (Dorper and Texel), by monitoring the environmental and physiological indicators related to heat tolerance. The experiment was carried out in a tropical climate region (Cwa), in Brazil, for twelve months, which comprised spring, summer, autumn and winter...
October 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/29026752/hwa-hypoferritinemia-without-anemia-a-hidden-hematology-disorder
#10
Hassan A Al-Jafar
INTRODUCTION: Anemia is a condition, in which the number of red blood cells (RBC) and the hemoglobin (Hb) is insufficient to meet the body's physiologic needs. Hypoferritinemia without anemia (HWA) could cause masked clinical manifestations as general weakness, easy fatigability, depressed mode, and hair loss but with normal complete blood count (CBC) parameters. HWA is deferent from iron deficiency anemia (IDA) because there is no reduction in the RBC, Hb, or any of the other parameters of the CBC...
January 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/28967977/nail-involvement-in-alopecia-areata-a-questionnaire-based-survey-of-impact-on-quality-of-life-and-review-of-the-literature
#11
Yvonne B M Roest, Henrià T van Middendorp, Andrea W M Evers, Peter C M van de Kerkhof, Marcel C Pasch
Alopecia areata (AA) is an immune-mediated disease causing temporary or permanent hair loss. Up to 46% of patients with AA also have nail involvement. The aim of this study was to determine the presence, types, and clinical implications of nail changes in patients with AA. This questionnaire-based survey evaluated 256 patients with AA. General demographic variables, specific nail changes, nail-related quality of life (QoL), and treatment history and need were evaluated. Prevalence of nail involvement in AA was 64...
October 2, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28965590/the-association-between-mercury-levels-and-autism-spectrum-disorders-a-systematic-review-and-meta-analysis
#12
Tina Jafari, Noushin Rostampour, Aziz A Fallah, Afshin Hesami
BACKGROUND & AIMS: The relationship between mercury and autism spectrum disorders (ASD) has always been a topic of controversy among researchers. This study aimed to assess the relationship between ASD and mercury levels in hair, urine, blood, red blood cells (RBC), and brain through a meta-analysis. METHODS: A systematic search was performed in several databases including PubMed, ISI Web of Science, Cochrane register of controlled trials, Google Scholar, Scopus, and MagIran until June 2017...
December 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/28960300/differentiation-of-human-hair-by-colour-and-diameter-using-light-microscopy-digital-imaging-and-statistical-analysis
#13
M Mills, J Bonetti, T Brettell, L Quarino
This research introduces and evaluates a novel method that offers the potential of providing objective criteria to forensic microscopical hair comparisons. The method combines hair diameter with numeric characterisations of red, green, and blue colour content as determined with the use of digital imaging at defined locations of the hair. Thirty hairs were collected from each of twenty participants, all with naturally coloured brown hair. The hairs were examined with an Olympus BX53® polarising light microscope and digital images were viewed with an Olympus DP72® camera under 400× magnification...
September 27, 2017: Journal of Microscopy
https://www.readbyqxmd.com/read/28956383/-factors-influencing-induction-and-in-vitro-culture-of-hairy-roots-in-phytolacca-americana-l
#14
Heping Shi, Yuanfeng Zhu, Po Keung Eric Tsang, Cheuk Fai Stephen Chow, Zhen'ao Yu, Shengqin Huang
To use hairy roots for producing medicinal ingredients of Phytolacca americana L. we studied the factors influencing the induction and in vitro culture. Hairy roots could be incited from the veins of cut surface (morphological lower) of P. americana L. leaf explants around 18 days after infection with the strain of Agrobacterium rhizogenes ATCC15834. The highest rooting rate, 70%, was obtained when leaf explants were pre-cultured for 1 day, infected for 20 min, and co-cultured for 4 days. The transformation was confirmed by PCR amplification of rolC of Ri plasmid and silica gel thin-layer chromatography of opines from P...
February 25, 2017: Sheng Wu Gong Cheng Xue Bao, Chinese Journal of Biotechnology
https://www.readbyqxmd.com/read/28950052/melanocortin-1-receptor-mc1r-polymorphisms-influence-on-size-and-dermoscopic-features-of-nevi
#15
María Gabriela Vallone, Gemma Tell-Marti, Miriam Potrony, Aida Rebollo-Morell, Celia Badenas, Joan Anton Puig-Butille, Pol Gimenez-Xavier, Cristina Carrera, Josep Malvehy, Susana Puig
The melanocortin 1 receptor (MC1R) is a highly polymorphic gene. The loss-of-function MC1R variants ("R") have been strongly associated with red hair color phenotype and an increased melanoma risk. We sequenced the MC1R gene in 175 healthy individuals to assess the influence of MC1R on nevus phenotype. We identified that MC1R variant carriers had larger nevi both on the back [p-value = .016, adjusted for multiple parameters (adj. p-value)] and on the upper limbs (adj. p-value = .007). Specifically, we identified a positive association between the "R" MC1R variants and visible vessels in nevi [p-value = ...
September 26, 2017: Pigment Cell & Melanoma Research
https://www.readbyqxmd.com/read/28944964/wnt-%C3%AE-catenin-and-erk-pathway-activation-a-possible-mechanism-of-photobiomodulation-therapy-with-light-emitting-diodes-that-regulate-the-proliferation-of-human-outer-root-sheath-cells
#16
Jung E Kim, Young J Woo, Ki M Sohn, Kwan H Jeong, Hoon Kang
BACKGROUND: Outer root sheath cells (ORSCs) play important roles in maintaining hair follicle structure and provide support for the bulge area. The hair growth promoting effects of photobiomodulation therapy (PBMT) have been reported, but the mechanisms for this in human ORCs (hORSCs) have rarely been studied. OBJECTIVE: The aim of this study was to investigate the effect of various wavelengths of light-emitting diode (LED) irradiation on human ORSCs (hORSCs). METHODS: LED irradiation effects on hORSC proliferation and migration were examined with MTT assay, BrdU incorporation assay and migration assays...
September 25, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28929966/-a-case-with-scalp-pruritus-caused-by-dermanysus-gallinae-order-mesostigmata
#17
Mustafa Şengül, Nida Kaçar, Mehmet Karaca, Sedef Zeliha Öner, Çağrı Ergin
Dermanyssus gallinae is one of the important hematophagous ectoparasite species of poultry like chicken, pigeon and wild bird species. These ectoparasites in the form of nymphs or adults who can not find their hosts are also seen in mammals and even in humans. For this reason, they are considered as important for public health. The ectoparasite causes a clinical condition named gamasoidosis among pet owners and people who live or work close to animal shelters, barns and chicken farms. Pruritus dermatitis is also caused by D...
July 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28928635/d-tubocurarine-and-berbamine-alkaloids-that-are-permeant-blockers-of-the-hair-cell-s-mechano-electrical-transducer-channel-and-protect-from-aminoglycoside-toxicity
#18
Nerissa K Kirkwood, Molly O'Reilly, Marco Derudas, Emma J Kenyon, Rosemary Huckvale, Sietse M van Netten, Simon E Ward, Guy P Richardson, Corné J Kros
Aminoglycoside antibiotics are widely used for the treatment of life-threatening bacterial infections, but cause permanent hearing loss in a substantial proportion of treated patients. The sensory hair cells of the inner ear are damaged following entry of these antibiotics via the mechano-electrical transducer (MET) channels located at the tips of the hair cell's stereocilia. d-Tubocurarine (dTC) is a MET channel blocker that reduces the loading of gentamicin-Texas Red (GTTR) into rat cochlear hair cells and protects them from gentamicin treatment...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28923545/computational-model-for-vitamin-d-deficiency-using-hair-mineral-analysis
#19
Aboul Ella Hassanien, Alaa Tharwat, Hala S Own
Vitamin D deficiency is prevalent in the Arabian Gulf region, especially among women. Recent studies show that the vitamin D deficiency is associated with a mineral status of a patient. Therefore, it is important to assess the mineral status of the patient to reveal the hidden mineral imbalance associated with vitamin D deficiency. A well-known test such as the red blood cells is fairly expensive, invasive, and less informative. On the other hand, a hair mineral analysis can be considered an accurate, excellent, highly informative tool to measure mineral imbalance associated with vitamin D deficiency...
August 30, 2017: Computational Biology and Chemistry
https://www.readbyqxmd.com/read/28915118/delayed-diagnosis-of-proopiomelanocortin-pomc-deficiency-with-type-1-diabetes-in-a-9-year-old-girl-and-her-infant-sibling
#20
Elif Ozsu, Allison Bahm
BACKGROUND: Proopiomelanocortin (POMC) protein, encoded by the POMC gene, is the precursor of adrenocorticotropic hormone (ACTH) that is released from the anterior pituitary gland. Homozygous mutations in the POMC gene is associated with hyperphagia, severe and early-onset obesity, adrenal insufficiency, hypopigmentation of the skin and red hair. CASE PRESENTATION: A 9-year-old girl from a consanguineous family of Iraqi origin was diagnosed with type 1 diabetes...
October 26, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
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