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https://www.readbyqxmd.com/read/29740476/milk-composition-for-admixed-dairy-cattle-in-tanzania
#1
Evans K Cheruiyot, Rawlynce C Bett, Joshua O Amimo, Fidalis D N Mujibi
It is well established that milk composition is affected by the breed and genotype of a cow. The present study investigated the relationship between the proportion of exotic genes and milk composition in Tanzanian crossbred dairy cows. Milk samples were collected from 209 animals kept under smallholder production systems in Rungwe and Lushoto districts of Tanzania. The milk samples were analyzed for the content of components including fat, protein, casein, lactose, solids-not-fat (SNF), and the total solids (TS) through infrared spectroscopy using Milko-Scan FT1 analyzer (Foss Electric, Denmark)...
2018: Frontiers in Genetics
https://www.readbyqxmd.com/read/29740017/atoh1-rfx1-rfx3-transcription-factors-facilitate-the-differentiation-and-characterisation-of-inner-ear-hair-cell-like-cells-from-patient-specific-induced-pluripotent-stem-cells-harbouring-a8344g-mutation-of-mitochondrial-dna
#2
Yen-Chun Chen, Chia-Ling Tsai, Yau-Huei Wei, Yu-Ting Wu, Wei-Ting Hsu, Hung-Ching Lin, Yi-Chao Hsu
Degeneration or loss of inner ear hair cells (HCs) is irreversible and results in sensorineural hearing loss (SHL). Human-induced pluripotent stem cells (hiPSCs) have been employed in disease modelling and cell therapy. Here, we propose a transcription factor (TF)-driven approach using ATOH1 and regulatory factor of x-box (RFX) genes to generate HC-like cells from hiPSCs. Our results suggest that ATOH1/RFX1/RFX3 could significantly increase the differentiation capacity of iPSCs into MYO7AmCherry -positive cells, upregulate the mRNA expression levels of HC-related genes and promote the differentiation of HCs with more mature stereociliary bundles...
April 19, 2018: Cell Death & Disease
https://www.readbyqxmd.com/read/29724829/genome-sequences-of-two-novel-papillomaviruses-isolated-from-healthy-skin-of-pudu-puda-and-cervus-elaphus-deer
#3
Beatriz Mengual-Chuliá, Ulrich Wittstatt, Philipp Olias, Ignacio G Bravo
We report the complete genome sequences of Pudu puda papillomavirus 1 (PpudPV1) and Cervus elaphus papillomavirus 2 (CelaPV2), isolated from healthy skin hair follicles of a Southern pudu and a red deer, respectively. PpudPV1 is basal to the DyokappaPVs, whereas CelaPV2 is basal to the XiPVs (Beta-XiPV crown group).
May 3, 2018: Genome Announcements
https://www.readbyqxmd.com/read/29692954/-kindia-pavetteae-rubiaceae-a-new-cliff-dwelling-genus-with-chemically-profiled-colleter-exudate-from-mt-gangan-republic-of-guinea
#4
Martin Cheek, Sékou Magassouba, Melanie-Jayne R Howes, Tokpa Doré, Saïdou Doumbouya, Denise Molmou, Aurélie Grall, Charlotte Couch, Isabel Larridon
A new genus Kindia (Pavetteae, Rubiaceae) is described with a single species, Kindia gangan , based on collections made in 2016 during botanical exploration of Mt Gangan, Kindia, Republic of Guinea in West Africa. The Mt Gangan area is known for its many endemic species including the only native non-neotropical Bromeliaceae Pitcairnia feliciana . Kindia is the fourth endemic vascular plant genus to be described from Guinea . Based on chloroplast sequence data, the genus is part of Clade II of tribe Pavetteae...
2018: PeerJ
https://www.readbyqxmd.com/read/29662168/genome-wide-association-meta-analysis-of-individuals-of-european-ancestry-identifies-new-loci-explaining-a-substantial-fraction-of-hair-color-variation-and-heritability
#5
Pirro G Hysi, Ana M Valdes, Fan Liu, Nicholas A Furlotte, David M Evans, Veronique Bataille, Alessia Visconti, Gibran Hemani, George McMahon, Susan M Ring, George Davey Smith, David L Duffy, Gu Zhu, Scott D Gordon, Sarah E Medland, Bochao D Lin, Gonneke Willemsen, Jouke Jan Hottenga, Dragana Vuckovic, Giorgia Girotto, Ilaria Gandin, Cinzia Sala, Maria Pina Concas, Marco Brumat, Paolo Gasparini, Daniela Toniolo, Massimiliano Cocca, Antonietta Robino, Seyhan Yazar, Alex W Hewitt, Yan Chen, Changqing Zeng, Andre G Uitterlinden, M Arfan Ikram, Merel A Hamer, Cornelia M van Duijn, Tamar Nijsten, David A Mackey, Mario Falchi, Dorret I Boomsma, Nicholas G Martin, David A Hinds, Manfred Kayser, Timothy D Spector
Hair color is one of the most recognizable visual traits in European populations and is under strong genetic control. Here we report the results of a genome-wide association study meta-analysis of almost 300,000 participants of European descent. We identified 123 autosomal and one X-chromosome loci significantly associated with hair color; all but 13 are novel. Collectively, single-nucleotide polymorphisms associated with hair color within these loci explain 34.6% of red hair, 24.8% of blond hair, and 26.1% of black hair heritability in the study populations...
April 16, 2018: Nature Genetics
https://www.readbyqxmd.com/read/29626271/bursal-immunopathology-responses-of-specific-pathogen-free-chickens-and-red-jungle-fowl-infected-with-very-virulent-infectious-bursal-disease-virus
#6
Mohd Isa Farhanah, Abdul Rahaman Yasmin, Nguyen Phuc Khanh, Swee Keong Yeap, Mohd Hair-Bejo, Abdul Rahman Omar
Very virulent infectious bursal disease virus (vvIBDV) targets B lymphocytes in the bursa of Fabricius (BF), causing immunosuppression and increased mortality rates in young birds. There have been few studies on the host immune response following vvIBDV infection at different inoculum doses in chickens with different genetic backgrounds. In this study, we characterized the immune responses of specific-pathogen-free (SPF) chickens and Malaysian red jungle fowl following infection with vvIBDV strain UPM0081 at 103...
April 6, 2018: Archives of Virology
https://www.readbyqxmd.com/read/29621642/adipose-derived-stem-cells-improve-full-thickness-skin-grafts-in-a-rat-model
#7
Silvana Bellini Vidor, Paula Barros Terraciano, Fernanda Soldatelli Valente, Verônica Machado Rolim, Cristiana Palma Kuhl, Laura Silveira Ayres, Tuane Nerissa Alves Garcez, Natália Emerim Lemos, Cristiano Ely Kipper, Sabrina Beal Pizzato, David Driemeier, Elizabeth Obino Cirne-Lima, Emerson Antonio Contesini
To investigate the effects of heterologous adipose-derived stem cells (ADSCs) on autologous full-thickness skin grafts, we designed a first-intention healing model using Wistar rats. We harvested and sutured two full-thickness skin grafts in the dorsal recipient beds of 15 rats, randomized into three groups. In the treatment group, 1 × 106 ADSCs resuspended in saline solution (200 μL) were administered subcutaneously to the skin graft. The control group received only saline solution subcutaneously, whereas the negative control group did not receive any treatment...
March 28, 2018: Research in Veterinary Science
https://www.readbyqxmd.com/read/29606656/engaging-oral-health-students-in-learning-basic-science-through-assessment-that-weaves-in-personal-experience
#8
Delyse Leadbeatter, Jinlong Gao
Learning basic science forms an essential foundation for oral health therapy and dentistry, but frequently students perceive it as difficult, dry, and disconnected from clinical practice. This perception is encouraged by assessment methods that reward fact memorization, such as objective examinations. This study evaluated use of a learner-centered assessment portfolio designed to increase student engagement with basic science in an oral health therapy program at the University of Sydney, Australia. The aim of this qualitative study based on focus groups was to investigate students' engagement with basic science courses following introduction of the portfolio...
April 2018: Journal of Dental Education
https://www.readbyqxmd.com/read/29574979/allergic-contact-dermatitis-caused-by-1-naphthol-a-red-coupler-in-a-purple-permanent-oxidative-hair-dye
#9
Thomas King, Ruth Sabroe, Catherine Holden
No abstract text is available yet for this article.
March 25, 2018: Contact Dermatitis
https://www.readbyqxmd.com/read/29531489/increased-iron-deficiency-and-iron-deficiency-anemia-in-children-with-zinc-deficiency
#10
Ayse Betul Ergul, Cem Turanoglu, Cigdem Karakukcu, Serap Karaman, Yasemin Altuner Torun
Objective: The aim of the present study is to determine the presence of iron (Fe) deficiency and Fe deficiency anemia in children with zinc (Zn) deficiency. Materials and Methods: This retrospective study comprised 560 patients aged 6 months to 16 years in whom Zn levels in hair samples were measured concurrently with serum levels of ferritin, Fe, Fe-binding capacity, and blood count analysis. For all patients, we retrospectively assessed serum ferritin, serum Fe, Fe-binding capacity, transferrin saturation index, red blood cell count, hemoglobin levels, hematocrit, mean corpuscular volume (MCV), mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, and red cell distribution width (RDW)...
February 2018: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/29530020/fatty-fish-intake-and-cognitive-function-fins-kids-a-randomized-controlled-trial-in-preschool-children
#11
RANDOMIZED CONTROLLED TRIAL
Jannike Øyen, Ingrid Kvestad, Lisa Kolden Midtbø, Ingvild Eide Graff, Mari Hysing, Kjell Morten Stormark, Maria Wik Markhus, Valborg Baste, Livar Frøyland, Berthold Koletzko, Hans Demmelmair, Lisbeth Dahl, Øyvind Lie, Marian Kjellevold
BACKGROUND: Marine resources including fatty fish are important sources of n-3 long chain polyunsaturated fatty acids (n-3 LC-PUFAs), which are important for brain development. To our knowledge, this is the first randomized controlled trial (RCT) investigating the impact of fatty fish on cognition in preschool children. The purpose of the trial was to investigate whether an increased intake of fatty fish compared to meat improves cognitive function in children 4-6 years old. METHODS: The children (n = 232) in this two-armed RCT, Fish Intervention Studies-KIDS (FINS-KIDS) were recruited from 13 kindergartens in Bergen, Norway...
March 12, 2018: BMC Medicine
https://www.readbyqxmd.com/read/29506886/is-eye-color-related-to-dental-injection-pain-a-prospective-randomized-single-blind-study
#12
Jason Hyde, Sara Fowler, Melissa Drum, Al Reader, John Nusstein, Mike Beck
INTRODUCTION: Recent studies have investigated the relationship between pain perception and specific phenotypes such as red hair color and various eye colors. Further investigations into biomarkers as they relate to pain could be useful in understanding underlying genetic components involved in these pathways. Additionally, it would be clinically useful to determine if a patient would be more likely to experience pain during dental treatment based on eye color. The purpose of this study was to investigate a link between eye color and perceived injection pain in healthy, asymptomatic white women...
May 2018: Journal of Endodontics
https://www.readbyqxmd.com/read/29502289/comparison-of-meat-quality-characteristics-and-fatty-acid-composition-of-finished-goat-kids-from-indigenous-and-dairy-breeds
#13
Hulya Yalcintan, Bulent Ekiz, Mustafa Ozcan
The aim of the study was to compare the certain carcass and meat quality traits and also fatty acid composition of goat kids from indigenous breeds (Gokceada and Hair Goat) and dairy breeds (Saanen and Maltese). A total 40 male kids from Saanen, Gokceada, Maltese and Hair Goat breeds were collected from commercial farms after weaning. Kids were finished for 56 days with grower concentrate and alfalfa hay in the sheepfold until slaughter. Higher mean values were found for Saanen kids in terms of slaughter weight, hot carcass weight and real dressing compared with Maltese, Hair Goat and Gokceada kids under the same intensive conditions...
March 3, 2018: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29468283/activation-of-wnt-%C3%AE-catenin-signaling-is-involved-in-hair-growth-promoting-effect-of-655-nm-red-light-and-led-in-in-vitro-culture-model
#14
Le Han, Ben Liu, Xianyan Chen, Haiyan Chen, Wenjia Deng, Changsheng Yang, Bin Ji, Miaojian Wan
Activation of the Wnt/β-catenin signaling pathway plays an important role in hair follicle morphogenesis and hair growth. Recently, low-level laser therapy (LLLT) was evaluated for stimulating hair growth in numerous clinical studies, in which 655-nm red light was found to be most effective and practical for stimulating hair growth. We evaluated whether 655-nm red light + light-emitting diode (LED) could promote human hair growth by activating Wnt/β-catenin signaling. An in vitro culture of human hair follicles (HFs) was irradiated with different intensities of 655-nm red light + LED, 21 h7 (an inhibitor of β-catenin), or both...
April 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29458150/pink1-protects-auditory-hair-cells-and-spiral-ganglion-neurons-from-cisplatin-induced-ototoxicity-via-inducing-autophagy-and-inhibiting-jnk-signaling-pathway
#15
Qianqian Yang, Gaoying Sun, Haiyan Yin, Hongrui Li, Zhixin Cao, Jinghan Wang, Meijuan Zhou, Haibo Wang, Jianfeng Li
Phosphatase and tensin homologue (PTEN)-induced putative kinase 1 (PINK1) gene encodes a serine/threonine kinase, which acts as a molecular sensor of mitochondrial health necessary for mitochondrial quality control. The present study was designed to examine whether PINK1 expressed in C57BL/6 murine cochlea and HEI-OC1 cells and, if so, to investigate the possible mechanisms underlying the action of PINK1 in cisplatin-induced death of sensory hair cells (HCs) and spiral ganglion neurons (SGNs) in vitro. The expression pattern of PINK1, formation of parkin particles, and autophagy were determined by immunofluorescent staining...
May 20, 2018: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/29435234/epizoochorous-dispersal-by-ungulates-depends-on-fur-grooming-and-social-interactions
#16
Océane Liehrmann, Flore Jégoux, Marie-Alice Guilbert, Francis Isselin-Nondedeu, Sonia Saïd, Yann Locatelli, Christophe Baltzinger
The transport phase of the animal-mediated plant dispersal process is critical to dispersal effectiveness as it determines the spatial distribution of the diaspores released and their chance for further recruitment. Assessing this specific phase of the dispersal process generally requires combining diaspore retention times with the associated distances covered. Here, we specifically tested the effect of grooming behavior, interindividual contacts and ungulate fur on diaspore retention times and associated dispersal distances for the hooked diaspores of Xanthium strumarium L...
February 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29403185/standardization-of-smp-procedure-and-its-impact-on-outcome
#17
Rachita S Dhurat, Sujit J S Shanshanwal, Ameet L Dandale
Background: Cosmetic deformities can result from various types of alopecia or even post hair transplantation procedures. Patients with such deformities seek aesthetically appealing longer-lasting options. Scalp concealers are commonly used by men and women to camouflage these deformities. Scalp micropigmentation (SMP) is one of the concealers recently gaining popularity. Objectives: SMP is a novel technique wherein microdot tattoos are placed in a stippling pattern to mimic hair follicles that are cut close to the scalp and various variables affecting its outcome were evaluated...
July 2017: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/29392864/an-efficient-method-for-eccrine-gland-isolation-from-human-scalp
#18
LETTER
Francisco Jimenez, Majid Alam, Irene Hernandez, Enrique Poblet, Jonathan A Hardman, Ralf Paus
We describe a simple and efficient method to isolate eccrine sweat glands from the human scalp. This method is inspired by the hair graft harvesting method used in hair transplantation. Based on the recently described anatomical relationship between the scalp hair follicle and the eccrine gland, we have found that scalp follicular unit grafts are an excellent eccrine gland isolation source, especially for the coiled component. In order to make the gland visible for stereoscopic microdissection, the follicular units need to be previously stained with a vital dye like methylene blue or neutral red...
February 2, 2018: Experimental Dermatology
https://www.readbyqxmd.com/read/29319595/pythium-keratitis-leading-to-fatal-cavernous-sinus-thrombophlebitis
#19
Anubha Rathi, Arunaloke Chakrabarti, Tushar Agarwal, Neelam Pushker, Mukesh Patil, Hemant Kamble, Jeewan S Titiyal, Rishi Mohan, Seema Kashyap, Sanjay Sharma, Seema Sen, Gita Satpathy, Namrata Sharma
PURPOSE: To report a case of Pythium insidiosum keratitis leading to fatal cavernous sinus thrombophlebitis. METHODS: Case report. RESULTS: A 70-year-old man presented with excruciating pain, redness, and diminution of vision in his left eye for 2 weeks after washing his hair with tap water. A total corneal ulcer with surrounding infiltrates and associated corneal thinning was present. Corneal scraping revealed the presence of Gram-positive cocci...
April 2018: Cornea
https://www.readbyqxmd.com/read/29318991/in-vitro-investigation-of-the-pediculicidal-activities-of-the-volatile-oil-components-of-some-medical-plants-raised-in-turkey
#20
M Emin Limoncu, Cüneyt Balcıoğlu, Tuğba Oyur, Gizem Zeybek, Ulvi Zeybek
OBJECTIVE: The human head louse Pediculus capitis has recently acquired resistance to commercially available insecticides, which has expanded the search concerning the pediculicidal activities of some herbal products. The present study aimed to assess the in vitro pediculicidal activities of volatile oils extracted from 10 medical plants raised in Turkey: Rosa damascena (red provins rose), Pelargonium graveolens (geranium), Lavandula angustifolia (lavender), Salvia triloba (salvia), Rosmarinus officinalis (rosemary; two different chemotypes), Citrus bergamia (citrus tree), Cymbopogon nardus (citronella), Citrus limonum (lemon), and Cymbopogon flexuosus (lemongrass)...
December 2017: Türkiye Parazitolojii Dergisi
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