Kelly Aubertin, Max Piffoux, Anna Sebbagh, Jeanne Gauthier, Amanda K A Silva, Florence Gazeau
Extracellular vesicles, secreted spontaneously or in response to stress by all cell types, are proposed as alternative biotherapies to cellular therapies and to synthetic nanomedicines. Their logistical advantages (storage, stability, availability, tolerance), their ability to cross biological barriers, to deliver their contents (proteins, lipids and nucleic acids) in order to modify their target cells, as well as their immunomodulatory and regenerative activities, are of growing interest for a very wide spectrum of diseases...
December 2021: Médecine Sciences: M/S