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Bone scintigraphy

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https://www.readbyqxmd.com/read/28099265/observer-agreement-of-treatment-responses-on-planar-bone-scintigraphy-in-prostate-cancer-patients-importance-of-the-lesion-assessment-method
#1
Randi F Fonager, Helle D Zacho, Signe Albertsen, Joan Fledelius, June A Ejlersen, Mette H Christensen, Ramune Aleksyniene, José A Biurrun Manresa, Lars J Petersen
PURPOSE: The aim of this study was to assess observer agreement on the evaluation of treatment responses of bone metastases by bone scintigraphy (BS) using different scoring methods in prostate cancer patients. PATIENTS AND METHODS: Sixty-three paired BS from 55 patients were included. BS was performed before and after more than 12 weeks of anticancer treatment. A panel of experienced nuclear medicine physicians from several institutions evaluated treatment response using three different methods: (a) standard clinical assessment, (b) MD Anderson criteria, and (c) Prostate Cancer Working Group 2 (PCWG-2) criteria...
January 17, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28089085/the-timing-of-bone-spect-to-predict-osteonecrosis-after-internal-fixation-of-femur-neck-fractures
#2
Ji Wan Kim, Jin-Sook Ryu, Sora Baek, Seong-Eun Byun, Jae Suk Chang
BACKGROUND: Bone SPECT can be used after a femur neck fracture to assess the circulation of the femoral head in the immediate postoperative period because the blood supply is one of the major factors affecting bone uptake of radiotracer on bone scintigraphy. The purpose of our present study was to investigate whether osteonecrosis of the femoral head (OFH) after internal fixation of femoral neck fracture could be predicted by early and late bone SPECT. METHODS: This retrospective cohort study enrolled 44 patients (33 women; mean age, 66...
January 6, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28074210/diagnostic-value-of-additional-68-ga-psma-pet-before-223-ra-dichloride-therapy-in-patients-with-metastatic-prostate-carcinoma
#3
Axel Bräuer, Kambiz Rahbar, Julia Konnert, Martin Bögemann, Lars Stegger
PURPOSE: Medical imaging plays an important role in selecting patients with metastatic castration-resistant prostate cancer for (223)Ra-dichloride therapy of bone metastases. The purpose of this study was to investigate whether (68)Ga-PSMA-PET has incremental value over conventional imaging for selecting patients suitable for (223)Ra-dichloride therapy. METHODS: In 27 consecutive patients referred for (223)Ra-dichloride therapy additional (68)Ga-PSMA-PET/CT was performed and tracer distribution was evaluated systematically with respect to the detection of visceral metastases and bone metastases with inadequate uptake on bone scintigraphy...
January 11, 2017: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/28058659/three-minute-spect-ct-is-sufficient-for-the-assessment-of-bone-metastasis-as-add-on-to-planar-bone-scintigraphy-prospective-head-to-head-comparison-to-11-min-spect-ct
#4
Helle D Zacho, José A Biurrun Manresa, Ramune Aleksyniene, June A Ejlersen, Joan Fledelius, Henrik Bertelsen, Lars J Petersen
BACKGROUND: The aim of this study is to assess whether ultra-fast acquisition SPECT/CT (UF-SPECT/CT) can replace standard SPECT/CT (std-SPECT/CT) as "add-on" to whole-body bone scintigraphy (WB-BS) for the investigation of bone metastases. Consecutive cancer patients referred for WB-BS who underwent SPECT/CT in addition to WB-BS were included. Std-SPECT, UF-SPECT, and low-dose CT were performed (std-SPECT: matrix 128 × 128, zoom factor 1, 20 s/view, 32 views; UF-SPECT: identical parameters except for 10 s/view and 16 views, reducing the acquisition time from 11 to 3 min)...
December 2017: EJNMMI Research
https://www.readbyqxmd.com/read/28051224/erdheim-chester-disease-and-radiobiphosphonates-bone-scan-from-a-simple-peripheral-form-to-a-rare-axial-location-a-case-report
#5
Salah Oueriagli Nabih
The Erdheim-Chester disease is a rare form of non Langherans histiocytosis. It can be expressed by a multi systemic disease interesting: bone, lung, heart, brain, retro peritoneum, skin and retro-orbital tissue. The diagnosis is established under the radiological aspect, bone scan uptake and immunohistological profile. The bone lesions are almost constant and rather characteristic of bone scintigraphy. We related the case of a young female patient of 26 years old with Erdheim-Chester bone disease. Diagnosis was revealed by diabetes insipidus (nerve damage) and diffuses bones pain...
June 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/28050818/what-is-the-accuracy-of-nuclear-imaging-in-the-assessment-of-periprosthetic-knee-infection-a-meta-analysis
#6
REVIEW
Steven J Verberne, Remko J A Sonnega, Olivier P P Temmerman, Pieter G Raijmakers
BACKGROUND: In the assessment of possible periprosthetic knee infection, various imaging modalities are used without consensus regarding the most accurate technique. QUESTIONS/PURPOSES: To perform a meta-analysis to compare the accuracy of various applied imaging modalities in the assessment of periprosthetic knee infection. METHODS: A systematic review and meta-analysis was conducted with a comprehensive search of MEDLINE and Embase(®) in accordance with the PRISMA and Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) recommendations to identify clinical studies in which periprosthetic knee infection was investigated with different imaging modalities...
January 3, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28033224/skeletal-scintigraphy-in-radiation-induced-fibrosis-with-lymphedema
#7
Jieqi Wang, Arya M Iranmanesh, M Elizabeth Oates
Despite increasing reliance on CT, MRI, and FDG PET/CT for oncological imaging, whole-body skeletal scintigraphy remains a frontline modality for staging and surveillance of osseous metastatic disease. We present a 54-year-old woman with metastatic breast cancer who received palliative external-beam radiation to the left ilium. Serial follow-up Tc-MDP bone scans demonstrated progressive soft-tissue uptake in her left lower extremity, extending from thigh to leg, with associated enlargement and skin thickening, consistent with lymphedema related to radiation-induced fibrosis...
December 28, 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28018063/endoprosthetic-reconstruction-for-metastatic-phaeochromocytoma-in-the-distal-femur-a-case-report
#8
Kanchana Pala Srikanth, Chirukuri Srinivas, Lakshmipura Gangadharaiah Gowrishankarswamy, Chikkamuniyappa Chandrasekar
Metastatic spread of malignant phaeochromocytoma is known to involve multiple organs including the axial skeleton. Its presentation as a solitary lesion in the long bones of the extremities is extremely rare. We report a unique case of solitary metastatic phaeochromocytoma presenting in the distal femur, 16 years after excision of primary abdominal tumor. A 60 year old female, operated for adrenal phaeochromocytoma 16 years back was detected to have a bone tumor in her left distal femur. Chest and abdominal CT evaluation including bone scintigraphy confirmed the lesion to be solitary...
October 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28012704/tomosynthesis-a-new-radiologic-technique-for%C3%A2-rapid-diagnosis-of-scaphoid-fractures
#9
N Compton, L Murphy, F Lyons, J Jones, P MacMahon, J Cashman
Scaphoid fractures constitute 71% of all carpal bone fractures.(1) Early diagnosis and treatment has significant bearing on fracture union rates and better clinical outcomes. While displaced fractures can be readily seen on plain radiograph, undisplaced fractures can require advanced imaging modalities to confirm that diagnosis. Advanced imaging such as Magnetic Resonance Imaging (MRI), Computerised tomography (CT) and bone scintigraphy are routinely used for the diagnosis of scaphoid fractures but require significant radiation exposure, increased cost and can be difficult to access...
December 21, 2016: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/28004130/multifocal-bone-and-bone-marrow-lesions-in-children-mri-findings
#10
Maria Raissaki, Stelios Demetriou, Konstantinos Spanakis, Christos Skiadas, Nikolaos Katzilakis, Emmanouil G Velivassakis, Eftichia Stiakaki, Apostolos H Karantanas
Polyostotic bone and bone marrow lesions in children may be due to various disorders. Radiographically, lytic lesions may become apparent after loss of more than 50% of the bone mineral content. Scintigraphy requires osteoblastic activity and is not specific. MRI may significantly contribute to the correct diagnosis and management. Accurate interpretation of MRI examinations requires understanding of the normal conversion pattern of bone marrow in childhood and of the appearances of red marrow rests and hyperplasia...
December 21, 2016: Pediatric Radiology
https://www.readbyqxmd.com/read/27997429/combined-18f-fdg-pet-ct-and-68ga-dotatate-pet-ct-superscan-in-metastatic-pancreatic-neuroendocrine-tumor
#11
Mico Chan, Geoffrey Paul Schembri
Metastatic neureoendocrine tumor to bone is well recognized. Typically, this has an appearance of multiple focal lesions. We present an example of diffuse skeletal involvement on both F-FDG PET/CT and Ga DOTATATE PET/CT with a pattern similar to the superscan appearance described on skeletal scintigraphy.
December 16, 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27997420/collar-osteophytes-mimicking-osteonecrosis-in-planar-bone-scintigraphy-and-usefulness-of-spect-ct-images
#12
Jr-Jian Juang, Yi-Hsing Chen, Shih-Chuan Tsai, Wan-Yu Lin
The use of prednisolone is one major risk factor for osteonecrosis in patients with systemic lupus erythematosus. Bone scintigraphy can be a diagnostic tool for early diagnosis. We present a case who had collar osteophytes at the bilateral femoral heads, which mimicked osteonecrosis in the planar bone scintigram. An SPECT/CT scan avoided this pitfall and increased the diagnostic accuracy for osteonecrosis.
December 16, 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27995542/bone-scan-index-of-the-jaw-a-new-approach-for-evaluating-early-stage-anti-resorptive-agents-related-osteonecrosis
#13
Satoru Watanabe, Kenichi Nakajima, Atsushi Mizokami, Hiroshi Yaegashi, Natsuyo Noguchi, Shuichi Kawashiri, Masafumi Inokuchi, Seigo Kinuya
OBJECTIVE: A computer-aided diagnosis of bone scintigraphy using a bone scan index (BSI) has not been applied to a diagnosis of anti-resorptive agents-related osteonecrosis of the jaw (ARONJ). The aim of this study was to validate a diagnostic ability of BSI for early-stage ARONJ. METHODS: A total of 44 cancer patients treated with anti-resorptive drugs were evaluated retrospectively. All patients underwent bone scintigraphy and the tracer uptakes were analyzed by BSI...
December 19, 2016: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/27941343/detection-of-prostate-cancer-metastasis-by-whole-body-magnetic-resonance-imaging-combined-with-bone-scintigraphy-and-psa-levels
#14
Hengqing An, Ning Tao, Jia Li, Yonghui Guan, Wenguang Wang, Yujie Wang, Feng Wang
BACKGROUND/AIMS: The combined role of whole-body magnetic resonance imaging (WB-MRI), bone scintigraphy and prostate specific antigen (PSA) were considered in predicting metastases and prognosis of prostate cancer (PCa). METHODS: Totally 38 PCa patients underwent WB-MRI, bone scintigraphy and PSA detections, and 34 benign prostate hyperplasia (BPH) patients were checked with PSA. Pearson correlations were performed to determine associations among PSA, apparent diffusion coefficient (ADC) and Gleason scoring...
2016: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/27935768/hypertrophic-osteoarthropathy-clinical-and-imaging-features
#15
Felix Y Yap, Matthew R Skalski, Dakshesh B Patel, Aaron J Schein, Eric A White, Anderanik Tomasian, Sulabha Masih, George R Matcuk
Hypertrophic osteoarthropathy (HOA) is a medical condition characterized by abnormal proliferation of skin and periosteal tissues involving the extremities and characterized by three clinical features: digital clubbing (also termed Hippocratic fingers), periostosis of tubular bones, and synovial effusions. HOA can be a primary entity, known as pachydermoperiostosis, or can be secondary to extraskeletal conditions, with different prognoses and management implications for each. There is a high association between secondary HOA and malignancy, especially non-small cell lung cancer...
January 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/27923351/intra-and-inter-observer-reliability-of-a-new-standardized-diagnostic-method-using-spect-ct-in-patients-with-osteochondral-lesions-of-the-ankle-joint
#16
Geneviève Hassink, Enrique A Testa, André Leumann, Thomas Hügle, Helmut Rasch, Michael T Hirschmann
BACKGROUND: Single Photon Emission Computed Tomography-Computed Tomography (SPECT/CT) gains an important part of diagnostics in patients with osteochondral lesions (OCL). SPECT/CT is a hybrid imaging modality, which combines a 3D scintigraphy (SPECT) and computerized tomography (CT) into one single procedure and combines metabolic data, structural and mechanical information. The purpose of the study was to develop and evaluate a standardized method to anatomically localize and quantitatively analyze the bone SPECT tracer activity of the ankle joint using SPECT/CT...
December 7, 2016: BMC Medical Imaging
https://www.readbyqxmd.com/read/27922864/99mtc-mdp-uptake-in-diffuse-pleural-recurrences-of-pulmonary-neuroendocrine-carcinoma
#17
Taisong Wang, Wenli Qiao, Yan Xing, Jinhua Zhao
A 39-year-old woman with a history of pulmonary neuroendocrine carcinoma segmental palliative resection underwent a Tc-MDP bone scintigraphy to evaluate possible osseous metastases. The static images revealed diffuse elevated activity in the left hemithorax, more prominent in the lower thorax, which is suggestive of malignant pleural effusion. However, SPECT/CT images showed that the elevated activity was from pleura-based soft tissue masses, which were confirmed as recurrent tumor pathologically after biopsy...
December 3, 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27922152/diagnosis-of-chronic-osteomyelitis-by-combined-99m-tc-bone-and-99m-tc-anti-granulocyte-scintigraphy
#18
Anne Frölich, Gotthard Knoll, Manfred Bähre, Christoph Neumann
No abstract text is available yet for this article.
December 6, 2016: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/27919970/11c-acetate-pet-ct-compared-to-99mtc-hdp-bone-scintigraphy-in-primary-staging-of-high-risk-prostate-cancer
#19
Sara Strandberg, Camilla Thellenberg Karlsson, Mattias Ogren, Jan Axelsson, Katrine Riklund
AIM: The aim of this study was to evaluate the detection rate of bone metastases and the added value of (11)C-acetate (ACE) positron-emission tomography/computed tomography (PET/CT) compared to bone scintigraphy (BS) in high-risk prostate cancer (PC). MATERIALS AND METHODS: A total of 66 untreated patients with high-risk PC with ACE-PET/CT and planar BS findings within 3 months of each other were retrospectively enrolled. Findings were compared and verified with follow-up data after an average of 26 months...
2016: Anticancer Research
https://www.readbyqxmd.com/read/27919134/-a-case-of-metastatic-tubulocystic-carcinoma-of-the-kidney-treated-with-molecularly-targeted-therapy
#20
Fumihiko Urabe, Jun Miki, Takafumi Yanagisawa, Takahiro Kimura, Masataka Nakano, Masafumi Suzuki, Koichi Kishimoto, Shin Egawa
A 51-year-old man who presented with gross hematuria and back pain was found to have a right renal mass accompanied with lung and osseous metastases. The patient underwent transabdominal right nephrectomy. The histopathological examination revealed the tumor to be tubulocystic carcinoma of the kidney. After the patient received sunitinib therapy, contrast enhanced computed tomography revealed that the metastatic tumor size was stable in the bone and decreased in the lung. Unfortunately, 9 months after nephrectomy, bone scintigraphy revealed an increase in the size of the metastatic tumor in the bone...
November 2016: Hinyokika Kiyo. Acta Urologica Japonica
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