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Bone scintigraphy

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https://www.readbyqxmd.com/read/28325501/imaging-in-myositis-ossificans-bone-scintigraphy-and-18f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography
#1
Marta Sánchez Aguilar, Rosario García Jiménez, Isabel Borrego Dorado
No abstract text is available yet for this article.
March 16, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/28324923/topotecan-vincristine-doxorubicin-in-stage-4-high-risk-neuroblastoma-patients-failing-to-achieve-a-complete-metastatic-response-to-rapid-cojec-a-siopen-study
#2
Loredana Amoroso, Giovanni Erminio, Guy Makin, Andrew Dj Pearson, Penelope Brock, Dominique Valteau-Couanet, Victoria Castel, Marlène Pasquet, Genevieve Laureys, Caroline Thomas, Roberto Luksch, Ruth Ladenstein, Riccardo Haupt, Alberto Garaventa
Purpose: Metastatic response to induction therapy for high-risk neuroblastoma is a prognostic factor. In the International Society of Paediatric Oncology Europe Neuroblastoma (SIOPEN) HR-NBL-1 protocol, only patients with metastatic complete response (CR) or partial response (PR) with ≤3 abnormal skeletal areas on 123iodine-metaiodobenzylguanidine ([123I]mIBG) scintigraphy and no bone marrow disease proceed to high dose therapy (HDT). In this study, topotecan-vincristine-doxorubicin (TVD) was evaluated in patients failing to achieve these criteria, with the aim of improving the metastatic response rate...
March 21, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28324123/long-term-bone-scintigraphy-results-after-intravenous-zoledronate-in-paget-s-disease-of-bone
#3
Ian R Reid, Katherine Maslowski
Zoledronate produces long-term normalization of biochemical markers in Paget's disease but whether this implies the absence of active disease is unknown. We have determined whether bone scintigraphy, a more sensitive index of disease activity, is also normalized ≥5 years after treatment with zoledronate. A consecutive case series of 11 individuals with Paget's disease treated with zoledronate 5 mg ≥5 years previously is reported. Eight patients received a single zoledronate infusion and were assessed 55-120 months later...
March 21, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28315917/a-pediatric-hypophosphatemic-rickets-on-mri-99m-tc-mdp-bone-scan-and-18-f-fdg-pet-ct
#4
Changyun Xu, Chao Ma, Yongli Bai
We present a case of a 13 years old boy who was hospitalized with a 10 months history of progressive pain and weakness in his lower extremities. The laboratory tests revealed slightly decreased phosphate and 25-hydroxyvitamin D3, high alkaline phosphatase, normal calcium and parathyroid hormone (PTH). Magnetic resonance imaging (MRI) showed multiple patchy lesions indicating bone destruction in the metaphyses and epiphyses of the left knee. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) revealed a generalized decrease of bone density in axial bones with slightly increased (18)F-FDG metabolism...
March 20, 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28314325/mic1-gdf15-as-a-bone-metastatic-disease-biomarker
#5
Jindra Windrichova, Radka Fuchsova, Radek Kucera, Ondrej Topolcan, Ondrej Fiala, Jindrich Finek, Dagmar Slipkova
AIM: The aim of the study was to evaluate MIC1/GDF15 as a biomarker in the monitoring of bone metastases occurrence. PATIENTS AND METHODS: The assessed group included patients diagnosed with: prostate cancer, breast cancer, lung cancer and colorectal cancer. Patients were divided into two groups based on the scintigraphy of the occurrence of bone metastases. Group 0 contained 55 patients without bone metastases, that served as the control group. Group 1 contained 75 patients with bone metastases...
March 2017: Anticancer Research
https://www.readbyqxmd.com/read/28301606/usefulness-of-bone-scintigraphy-for-the-diagnosis-of-complex-regional-pain-syndrome-1-a-systematic-review-and-bayesian-meta-analysis
#6
Maria M Wertli, Florian Brunner, Johann Steurer, Ulrike Held
BACKGROUND: Since 2007, the Budapest criteria are recommended for the diagnosis of Complex Regional Pain Syndrome (CRPS) 1. The usefulness of bone scintigraphy (BS, index test) for the diagnosis of CRPS 1 remains controversial. Imperfect reference tests (RT) result in underestimation of the diagnostic accuracy of BS. Further, biased results can occur when a dependency between the RT and BS exists. The objective was to assess the impact of different RTs, specifically the Budapest criteria, and the assumed imperfect nature of the RT on the diagnostic accuracy of BS...
2017: PloS One
https://www.readbyqxmd.com/read/28288045/lower-extremity-pseudomyogenic-hemangioendothelioma-on-bone-scintigraphy-and-pet-ct
#7
Simone Krebs, Serena Monti, Natasha Lewis, Alessandro Luciano, Lapo Rastrelli, Lorenzo Mannelli
An otherwise healthy 33-year-old man presents with new pain involving the right leg. Radiographs of the femur showed scattered lucent lesions. An MRI of the knee demonstrated nonspecific cortical-based lesions. Biopsy confirmed pseudomyogenic hemangioendothelioma. MDP bone scan and F-FDG PET/CT were obtained to evaluate for extent of disease demonstrating disease limited to the bone of the right leg. Interestingly, the FDG and MDP uptake and CT appearance of the disease were not entirely concordant, with some lesions being lytic on CT and associated with FDG and MDP uptake, other lesions being CT silent and either MDP or FDG avid...
March 10, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28288044/the-accessory-sacroiliac-joint-diagnosed-with-bone-spect-ct
#8
Ji-Hun Kang, Min-Woo Kim, Eun Ha Moon, Young Jun Kim, Ki Pi Yu
The accessory sacroiliac (SI) joint is not rare and can be one of the causes of lower back pain. We present a case of a 35-year-old woman with chronic lower back pain. Conventional radiography was equivocal, and bone scintigraphy showed a focus of mildly increased uptake in left SI joint region. SPECT/CT revealed increased uptakes in the accessory articulations between both sacral alae and iliac bones, and confirmed the diagnosis of accessory SI joint. This case illustrates the SPECT/CT findings of the accessory SI joint...
March 10, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28268124/-usefulness-of-nuclear-medicine-in-erdheim-chester-disease-a-lille-experience
#9
A Adens, P Landy, L Terriou, C Baillet, A Beron, M Lambert, D Launay, D Huglo
INTRODUCTION: Erdheim-Chester disease is a rare form of non-langerhans histiocytosis and its etiology is still not well established. The aims of the study were to assess the value of the bone scintigraphy and the (18)F-FDG PET/CT for the diagnostic and for the latter in the therapeutic evaluation. METHODS: We retrospectively reviewed 49 patients suspected of Erdheim-Chester disease between 2004 and 2016. Bone scintigraphy was compared with histopathology and PET-CT to conventional morphological examinations and bone scintigraphy...
March 3, 2017: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/28266288/parathyroid-adenomas-in-adults-and-adolescents-critical-appraisal-and-surgical-strategy-in-18-cases
#10
Mihai Radu Diaconescu, Ioan Costea, Mihai Glod, Radu Terinte, Smaranda Diaconescu
Background: Our study underline scarcity of isolated case reports or small case series of parathyroid adenoma (PA) published in autochthonous medical literature,their variable clinical expression among the "historic" varieties but also the diagnostic difficulties and delays of diagnosis as well consecration of surgery as the golden therapeutic standard of this disorder. PATIENTS AND METHOD: Demographic, clinical presentations, laboratory and imaging data, operative findings and procedures together with pathology account and outcome from the case reports of 18 patients with documented PHP were retrospectively analyzed...
January 2017: Chirurgia
https://www.readbyqxmd.com/read/28265641/-nuclear-medicine-in-germany-updated-key-data-and-trends-from-official-statistics
#11
Dirk Hellwig, Jörg Marienhagen, Karin Menhart, Jirka Grosse
AIM: Updated presentation of the spectrum of nuclear medicine in-vivo examinations and therapies from officially available statistics on out-patient and in-patient care as well as trends of structural data on nuclear medicine in Germany. METHODS: Data from the German Federal Health Monitoring, from the frequency statistics of the statutory health insurance for out-patients and from the German Medical Association were used and supplemented by data from selective literature searches...
March 7, 2017: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/28263216/incidental-99m-tc-hdp-uptake-in-a-dominant-thyroid-nodule-on-bone-scan
#12
Deepa Shetty, Grace Yung, Roberto Russo, Robert Mansberg
A 67-year-old woman was referred for a bone scan for evaluation of increasing serum alkaline phosphatase levels. Bone scan revealed no abnormal uptake in the skeleton. However, intense hypervascularity and delayed tracer uptake were incidentally identified in an enlarged right thyroid gland. A thyroid scintigraphy, contrast-enhanced CT of the neck, and sonographic evaluation of the abnormality were subsequently organized to characterize the lesion. An ultrasound-guided fine-needle aspiration revealed a benign follicular pattern (Bethesda II), and histopathology of the right hemithyroidectomy confirmed a dominant nodule within a nodular goiter...
March 3, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28256425/comparison-of-99m-tc-mdp-spect-qualitative-vs-quantitative-results-in-patients-with-suspected-condylar-hyperplasia
#13
D F López Buitrago, J Ruiz Botero, C M Corral, A R Carmona, A Sabogal
OBJECTIVE: To compare qualitative vs quantitative results of Single Photon Emission Computerised Tomography (SPECT), calculated from percentage of (99m)Tc-MDP (methylene diphosphonate) uptake, in condyles of patients with a presumptive clinical diagnosis of condylar hyperplasia. MATERIALS AND METHOD: A retrospective, descriptive study was conducted on the (99m)Tc-MDP SPECT bone scintigraphy reports from 51 patients, with clinical impression of facial asymmetry related to condylar hyperplasia referred by their specialist in orthodontics or maxillofacial surgery, to a nuclear medicine department in order to take this type of test...
February 28, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28256403/the-utility-of-99m-tc-dpd-scintigraphy-in-the-diagnosis-of-cardiac-amyloidosis-an-australian-experience
#14
Peter T Moore, Matthew K Burrage, Emily Mackenzie, W Philip Law, Dariusz Korczyk, Peter Mollee
BACKGROUND: The uptake of bone-seeking radiotracers in the amyloid heart is well recognised. 99(m)Tc-DPD has been shown to be highly sensitive for cardiac transthyretin (ATTR) amyloid in an overseas population, but is not registered for use in Australia. We explored its utility as a diagnostic tool within our population. METHODS: Patients diagnosed with AL and ATTR (wild-type and inherited) cardiac amyloidosis were prospectively recruited from the Princess Alexandra Hospital Amyloidosis Centre...
February 16, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28248672/can-imaging-modalities-be-used-as-follow-up-criteria-after-brucellar-sacroiliitis-treatment
#15
Aybars Bilgeturk, Hanefi Cem Gul, Ahmet Karakas, Gurkan Mert, Cumhur Artuk, Can Polat Eyigun
INTRODUCTION: This study aimed to identify a follow-up modality that can be used to evaluate therapeutic responses in patients receiving treatment for brucellar sacroillitis and to determine whether antibiotherapy can be stopped. METHODOLOGY: A total of 32 patients with sacroiliac joint involvement demonstrated via magnetic resonance imaging or bone scintigraphy were followed up and treated. Patients received 200 mg/day of doxycycline and 600-900 mg/day of rifampicin for 3-21 months, and 1 g/day of streptomycin for 21 days...
February 28, 2017: Journal of Infection in Developing Countries
https://www.readbyqxmd.com/read/28244493/imaging-response-during-therapy-with-radium-223-for-castration-resistant-prostate-cancer-with-bone-metastases-analysis-of-an-international-multicenter-database
#16
D Keizman, M O Fosboel, H Reichegger, A Peer, E Rosenbaum, M-C Desax, V Neiman, P M Petersen, J Mueller, R Cathomas, M Gottfried, H Dresler, D Sarid, W Mermershtain, K Rouvinov, J Mortensen, S Gillessen, G Daugaard, A Omlin
BACKGROUND: The imaging response to radium-223 therapy is at present poorly described. We aimed to describe the imaging response to radium-223 treatment. METHODS: We retrospectively evaluated the computed tomography (CT) and bone scintigraphy response of metastatic castration-resistant prostate cancer (CRPC) patients treated with radium-223, in eight centers in three countries. RESULTS: A total of 130 patients were included, the majority (n=84, 65%) received radium-223 post docetaxel...
February 28, 2017: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/28243844/3d-spect-ct-fusion-using-image-data-projection-of-bone-spect-onto-3d-volume-rendered-ct-images-feasibility-and-clinical-impact-in-the-diagnosis-of-bone-metastasis
#17
Yuji Ogata, Tadaki Nakahara, Kenichi Ode, Yohji Matsusaka, Mari Katagiri, Yu Iwabuchi, Kazunari Itoh, Akira Ichimura, Masahiro Jinzaki
PURPOSE: We developed a method of image data projection of bone SPECT into 3D volume-rendered CT images for 3D SPECT/CT fusion. The aims of our study were to evaluate its feasibility and clinical usefulness. METHODS: Whole-body bone scintigraphy (WB) and SPECT/CT scans were performed in 318 cancer patients using a dedicated SPECT/CT systems. Volume data of bone SPECT and CT were fused to obtain 2D SPECT/CT images. To generate our 3D SPECT/CT images, colored voxel data of bone SPECT were projected onto the corresponding location of the volume-rendered CT data after a semi-automatic bone extraction...
February 27, 2017: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/28242981/hepatitis-c-virus-related-arthritis-bone-scintigraphic-appearances
#18
Gul Ege Aktas, Ali Sarikaya, Ozan Kandemir
A symptomatic joint involvement and arthralgia are frequent in patients with chronic hepatitis C virus (HCV) infection. However, HCV infection-related arthritis (HCVrA) affects up to 4-11% of the subjects suffering from disease. We reported a patient with HCVrA presented with the commonly accepted diagnostic clinical signs and laboratory parameters. The painful joints distinctly demonstrated increased uptake of Tc-99 m methylene diphosphonate in scintigraphy and normal findings in radiography.
January 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28240671/solitary-thumb-acrometastasis-identified-on-bone-scintigraphy
#19
Peng Xie, Jianmin Huang
A 45-year-old man with a history of adenocarcinoma in the right lung 3 years ago underwent a Tc-MDP bone scan to evaluate possible osseous metastasis. The images demonstrated intense activity in the region of left thumb, while the tracer uptakes in other bones were not typical of metastases. A CT of the hand showed diffuse sclerotic changes with destructed trabecular structure in the proximal phalanx of the left thumb. The left thumb was subsequently resected, and the pathological examination of the resected left first metacarpal bone confirmed the diagnosis of metastasis of lung adenocarcinoma...
February 24, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28240655/impending-atypical-femoral-fracture-in-patients-with-medullary-thyroid-cancer-with-skeletal-metastasis-treated-with-long-term-bisphosphonate-and-denosumab
#20
Mitsuru Koizumi, Tabu Gokita, Kazuhisa Toda
Atypical femoral fractures (AFFs) occur in osteoporosis patients receiving long-term bisphosphonate. Atypical femoral fractures also occur in cancer patients receiving long-term bisphosphonate or denosumab, but the prevalence is low. We describe a 53-year-old woman with a history of medullary thyroid cancer and skull metastasis who was prescribed bisphosphonate for 6 years and denosumab for 1.5 years, consecutively. Bone scintigraphy performed because of spontaneous groin pain showed uptake in the lateral aspect of the left femur, which was confirmed as impending AFF...
February 24, 2017: Clinical Nuclear Medicine
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