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Bone scintigraphy

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https://www.readbyqxmd.com/read/28730243/a-52-year-old-man-with-gouty-arthritis-and-erosive-lesion-in-the-hip
#1
Vitorino Modesto Dos Santos, Viviane Vieira Passini Soares, Priscilla Souza de Faria, Francisca Germanya Morais Borges Viana, Mayza Lemes Duarte
The case study of peripheral and axial gouty arthritis is described in a 52-year-old man without concomitant clinical evidence of tophaceus gout on physical evaluation on admission. Gout is a metabolic disorder related to excess of uric acid in the extracellular compartment, and deposition of monosodium urate crystals in the joints and other sites. Arthritis and tophi are major manifestations, which more often involve the peripheral joints asymmetrically. Chronic tophaceous gout commonly develops after a decade of recurrent polyarticular gout...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28729430/imaging-chemokine-receptor-cxcr4-in-chronic-infection-of-the-bone-with-68-ga-pentixafor-pet-ct-first-insights
#2
Caroline Bouter, Birgit Meller, Carsten Oliver Sahlmann, Wieland Staab, Hans Jürgen Wester, Saskia Kropf, Johannes Meller
Due to its role in infection and inflammatory processes the chemokine receptor CXCR4 might be a potent target in imaging of infectious and inflammatory diseases. The aim of this pilot study was to determine whether the CXCR4 ligand (68)Ga-Pentixafor is suitable for imaging chronic infection of the bone. Methods: The study comprises 14 patients with suspected infection of the skeleton that underwent (68)Ga-Pentixafor-(68)Ga-Pentixafor-Positron emission tomography/computed tomography(PET/CT) between 04/2015 and 02/2017 in our facility...
July 20, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28726977/added-value-of-spect-spiral-ct-versus-spect-or-ct-alone-in-diagnosing-solitary-skeletal-lesions
#3
Yiqiu Zhang, Beilei Li, Hongcheng Shi, Haojun Yu, Yushen Gu, Yan Xiu
AIM: The aim of this study was to investigate the added value of SPECT/spiral CT versus SPECT or CT alone in the differential diagnosis of solitary skeletal lesions. METHODS: This was a retrospective study on a total of 69 patients who had a solitary skeletal "hot spot" that could not be definitively diagnosed using planar scintigraphy. Thus, SPECT/spiral CT was performed on the indeterminate lesions. SPECT, CT and SPECT/spiral CT images were independently interpreted by two experienced doctors who have both identification of CT and nuclear medicine...
July 20, 2017: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/28725949/tubulointerstitial-nephritis-induced-hypophosphatemic-osteomalacia-in-sj%C3%A3-gren-s-syndrome-a-case-report-and-review-of-the-literature
#4
REVIEW
Yan Geng, Youlu Zhao, Zhuoli Zhang
Sjögren's syndrome (SS) is a chronic autoimmune inflammatory disease that typically affects the salivary and lacrimal glands. Renal involvement is relatively uncommon and may precede other complaints. Tubulointestitial nephritis (TIN) is the most common renal involvement in SS. Osteomalacia occurring as the first manifestation of renal tubular disorder due to SS is very rare. We report a 39-year-old male who presented with polydipsia, polyuria, and multiple bone pain. Bone density test showed severe osteoporosis, and laboratory findings suggested hypokalemia, hypophosphatemia, and vitamin D deficiency, which supported the diagnosis of hypophosphatemic osteomalacia...
July 20, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28723520/bone-scan-index-as-an-imaging-biomarker-in-metastatic-castration-resistant-prostate-cancer-a-multicentre-study-based-on-patients-treated-with-abiraterone-acetate-zytiga-in-clinical-practice
#5
Mariana Reza, Mattias Ohlsson, Reza Kaboteh, Aseem Anand, Ingela Franck-Lissbrant, Jan-Erik Damber, Anders Widmark, Camilla Thellenberg-Karlsson, Lars Budäus, Thomas Steuber, Till Eichenauer, Per Wollmer, Lars Edenbrandt, Elin Trägårdh, Anders Bjartell
BACKGROUND: Abiraterone acetate (AA) prolongs survival in metastatic castration-resistant prostate cancer (mCRPC) patients. To measure treatment response accurately in bone, quantitative methods are needed. The Bone Scan Index (BSI), a prognostic imaging biomarker, reflects the tumour burden in bone as a percentage of the total skeletal mass calculated from bone scintigraphy. OBJECTIVE: To evaluate the value of BSI as a biomarker for outcome evaluation in mCRPC patients on treatment with AA according to clinical routine...
December 2016: European Urology Focus
https://www.readbyqxmd.com/read/28721304/imaging-features-of-paget-s-disease-on-11-c-choline-pet-ct
#6
Cameron E Leitch, Ajit H Goenka, Benjamin M Howe, Stephen M Broski
The purpose of this study was to investigate the appearance of Paget's disease (PD) on (11)C choline PET/CT and correlate these findings to serum alkaline phosphatase (ALP) level and skeletal scintigraphy. With IRB approval, our institutional (11)C choline PET/CT database (9/2005-6/2015) was searched for patients with PD. Site of osseous involvement, CT appearance, and multiple semi-quantitative measures were measured and correlated with ALP and degree of uptake on bone scan. Our search identified 10 males (mean age 79...
2017: American Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28707737/-18-f-sodium-fluoride-positron-emission-tomography-of-the-equine-distal-limb-exploratory-study-in-three-horses
#7
M Spriet, P Espinosa, A Z Kyme, K L Phillips, S A Katzman, L D Galuppo, P Stepanov, D Beylin
BACKGROUND: Positron Emission Tomography (PET) is a cross-sectional, functional imaging modality that has recently become available to the horse. The use of (18) F-sodium fluoride ((18) F-NaF), a PET bone tracer, has never been reported in this species. OBJECTIVES: To assess the feasibility of (18) F-NaF PET in the equine distal limb and explore possible applications in the horse in comparison with other imaging modalities. STUDY DESIGN: Exploratory descriptive study involving three research horses...
July 14, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28693433/prospective-evaluation-of-computer-assisted-analysis-of-skeletal-lesions-for-the-staging-of-prostate-cancer
#8
Lars J Petersen, Jesper C Mortensen, Henrik Bertelsen, Helle D Zacho
BACKGROUND: The purpose of this study was to compare the agreement of the bone scan index (BSI) using EXINI Bone(BSI) versus experts' readings in the initial staging for bone metastasis in prostate cancer. In addition, the diagnostic outcome was assessed in a large subset of patients where a true reference for metastases could be determined based on clinical and biochemical follow-up and/or supplementary imaging. METHODS: A total of 342 patients had a bone scintigraphy as part of routine staging for prostate cancer...
July 10, 2017: BMC Medical Imaging
https://www.readbyqxmd.com/read/28692495/the-clinical-significance-of-technetium-99m-methylene-diphosphonate-bone-scintigraphy-findings-in-patients-with-rhabdomyolysis
#9
Jeong Won Lee, Eun-Young Lee, Sae-Yong Hong, Ik Dong Yoo, Sang Mi Lee
OBJECTIVE: This study evaluated the relationship between bone scintigraphy finding and clinical factors and assessed the prognostic value of bone scintigraphy finding in patients with rhabdomyolysis. PATIENTS AND METHODS: We retrospectively enrolled 143 patients with rhabdomyolysis who had undergone bone scintigraphy. Bone scintigraphy was classified into three groups: no or equivocal soft tissue uptake, a localized uptake, and a diffuse uptake. The relationship of bone scintigraphy findings with clinical factors was evaluated...
July 7, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28682867/camurati-engelmann-disease-a-rare-cause-of-tetany-identified-on-bone-scintigraphy-a-case-report
#10
Peng Xie, Jian-Min Huang, Huan-Li Li, Xiao-Jie Huang, Ling-Ge Wei
RATIONALE: Camurati-Engelmann disease (i.e., progressive diaphyseal dysplasia) is an extremely rare autosomal dominant bone disorder. The most common clinical manifestations were chronic skeletal pain, waddling gait, muscular weakness. PATIENT CONCERNS: We described that a 27-year-old male with a 1-year history of intermittent tetany was referred for bone scintigraphy. The whole body bone scan images showed abnormal increased uptake of the tracer in the long bones of the upper and lower extremities as well as in the skull...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28680220/myofascial-pain-syndrome-on-tc99m-mdp-bone-scintigraphy
#11
Rola Aatif Hasan Hussain, Ammar Mohammed Saeed Ali, K Manivannan, S K Chirala
No abstract text is available yet for this article.
July 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28666404/neck-pain-associated-with-a-bony-metastatic-tumor
#12
Maria Alice Mainenti Pagnez, Leandro Calazans Nogueira, James M Elliott
A 78-year-old man was referred to physical therapy with a 5-month history of nontraumatic neck pain and reductions in active bilateral rotation without radiculopathy. Radiography and computed tomography taken 2 months prior demonstrated age-related multilevel degenerative disc disease. Following physical therapy with no improvement in symptoms, magnetic resonance imaging with contrast and bone scintigraphy were ordered by the physician. An expansile lesion in the right lateral mass of the atlas on magnetic resonance imaging was consistent with a metastatic activity...
July 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28657567/bone-scan-in-painful-knee-arthroplasty-obsolete-or-actual-examination
#13
Giuseppe Niccoli, Domenico Mercurio, Fabrizio Cortese
ptic loosening, instability and infection are the major causes of TKA failure. For many years, nuclear medicine (NM) imaging was helpful to frame a painful total joint arthroplasty. The differentiation of septic from aseptic prosthetic loosening is critical. The latest AAOS guidelines to detect periprosthetic joint infection (PJI) restrict the role of NM scintigraphy. On the other hand, several studies suggest that NM imaging plays an important role in the evaluation of patients with painful prosthesis, but its specificity in differentiating aseptic loosening from infection is low...
June 7, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/28639953/impressive-paget-disease-of-the-lumbar-spine-masks-the-coexisting-multiple-myeloma
#14
Xiao Zhong, Yunxia Ye, Xiaohong Ou
Multimodality imaging, including MRI, bone scintigraphy, and FDG PET/CT, was performed to evaluate a 49-year-old man who had right hip and lower limb pain for 4 months because possible malignancy was suspected. All 3 modalities showed obvious Paget disease of the lumbar spine. However, less impressive increased activity was also noted on FDG PET/CT images. Subsequent laboratory tests and pathology examination leads to diagnosis of multiple myeloma. Our case further confirms the notion that it is insufficient to focus on the most obvious and unintentionally overlook the less impressive findings in interpreting nuclear medicine images...
June 20, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28620059/anakinra-in-a-cohort-of-children-with-chronic-nonbacterial-osteomyelitis
#15
Manuela Pardeo, Denise Pires Marafon, Virginia Messia, Maria Carmen Garganese, Fabrizio De Benedetti, Antonella Insalaco
OBJECTIVE: To report efficacy and safety in patients with chronic nonbacterial osteomyelitis (CNO) unresponsive to nonsteroidal antiinflammatory drugs (NSAID) and bisphosphonates and/or glucocorticoids treated with anakinra. METHODS: Nine patients (6 females) with refractory CNO were treated with anakinra for at least 6 months. We recorded, at baseline and after 6 months of treatment, clinical and laboratory features, and number and distribution of bone lesions detected by 99mTc-MDP bone scintigraphy...
June 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28606069/when-to-perform-bone-scintigraphy-in-patients-with-newly-diagnosed-prostate-cancer-a-retrospective-study
#16
Yiwei Lin, Qiqi Mao, Bin Chen, Liujiang Wang, Ben Liu, Xiangyi Zheng, Liping Xie
BACKGROUND: To determine when a bone scintigraphy investigation is appropriate in patients with newly diagnosed prostate cancer (PCa). METHODS: We retrospectively reviewed 703 newly diagnosed PCa patients who were referred for bone scintigraphy. The association between age, prostate specific antigen (PSA), Gleason score (GS) and bone scintigraphy result were investigated by series of crude or stratified analysis. RESULTS: Overall, 15.08% (106/703) patients had bone metastases...
June 12, 2017: BMC Urology
https://www.readbyqxmd.com/read/28605001/determination-of-structural-femoral-head-allograft-viability-and-integrity-with-a-novel-diagnostic-tool-spect-ct-a-preliminary-study
#17
Kasım Kilicarslan, Nadir Yalcin, Vedat Bicici, Elif Ozdemir, Izzet Bingol, Seyda Turkolmez
OBJECTIVE: To evaluate the viability and integrity of fresh frozen bulk femoral head allografts obtained from the institutional bone bank that were used to reconstruct severe acetabular defects and to validate the SPECT/CT method which gives both anatomical and functional data for this purpose. METHODS: We retrospectively reviewed 9 patients (6 female, 3 male; mean age 63.6 years). Preoperative and postoperative leg lengths, existence of the Trendelenburg sign, range of motion of the hip, visual analogue score (VAS), Harris Hip Score (HHS) and any complication were assesed at each follow-up...
June 2, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28602048/injected-corticosteroids-for-treating-plantar-heel-pain-in-adults
#18
REVIEW
Judy A David, Venkatesan Sankarapandian, Prince Rh Christopher, Ahana Chatterjee, Ashish S Macaden
BACKGROUND: Plantar heel pain, commonly resulting from plantar fasciitis, often results in significant morbidity. Treatment options include nonsteroidal anti-inflammatory drugs (NSAIDs), orthoses, physical therapy, physical agents (e.g. extracorporeal shock wave therapy (ESWT), laser) and invasive procedures including steroid injections. OBJECTIVES: To assess the effects (benefits and harms) of injected corticosteroids for treating plantar heel pain in adults. SEARCH METHODS: We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register, the Cochrane Central Register of Controlled Trials (the Cochrane Library), MEDLINE, Embase, CINAHL, clinical trials registries and conference proceedings...
June 11, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28598184/surface-electromyography-before-and-after-orthognathic-surgery-and-condylectomy-in-active-laterognathia-a-case-report
#19
F Cullati, A Mapelli, G Beltramini, M Codari, C L Pimenta Ferreira, A Baj, A B Giannì, C Sforza
BACKGROUND: Condylar hyperplasia is a rare bone disease characterised by excessive development of mandibular condyle, which can lead to the development of asymmetric facial deformity together with malocclusion, mandibular deviation, TMJ and masticatory musculoskeletal system dysfunction. There is not a treatment protocol universally accepted. In order to determine the correct management, treatment and intervention timing of these patients, morphological examinations should be coupled with functional assessments...
June 2017: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28592305/incremental-diagnostic-utility-of-systematic-double-bed-spect-ct-for-bone-scintigraphy-in-initial-staging-of-cancer-patients
#20
Catherine Guezennec, Nathalie Keromnes, Philippe Robin, Ronan Abgral, David Bourhis, Solène Querellou, Romain de Laroche, Alexandra Le Duc-Pennec, Pierre-Yves Salaün, Pierre-Yves Le Roux
BACKGROUND: SPECT/CT has been shown to increase the diagnostic performance of bone scintigraphy for staging of malignancies. A systematic double-bed SPECT/CT of the trunk may allow further improvement. However, this would be balanced by higher dosimetry and longer acquisition time. The objective was to assess the incremental diagnostic utility of a systematic double-bed SPECT/CT acquisition for bone scintigraphy in initial staging of cancer patients, especially compared with the usual approach consisting in a whole body planar scan (WBS) plus one single-bed targeted SPECT/CT...
June 7, 2017: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
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