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Central line associated blood stream infections

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https://www.readbyqxmd.com/read/28687213/prevention-of-central-line-associated-bloodstream-infections
#1
REVIEW
Taison Bell, Naomi P O'Grady
Central venous catheters (CVCs) are commonly used in critically ill patients and offer several advantages to peripheral intravenous access. However, indwelling CVCs have the potential to lead to blood stream infections, with the risk increasing with an array of characteristics such as catheter choice, catheter location, insertion technique, and catheter maintenance. Evidence-based guidelines have led to a significant reduction in the incidence of blood stream infections associated with CVCs. The combination of guideline implementation and newer technologies has the potential to further reduce morbidity and mortality from infections related to CVCs...
July 5, 2017: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/28663107/prevention-of-central-venous-line-associated-bloodstream-infections-in-adult-intensive-care-units-a-systematic-review
#2
Diana Carolina Velasquez Reyes, Melissa Bloomer, Julia Morphet
BACKGROUND: In adult Intensive Care Units, the complexity of patient treatment requirements make the use of central venous lines essential. Despite the potential benefits central venous lines can have for patients, there is a high risk of bloodstream infection associated with these catheters. AIM: Identify and critique the best available evidence regarding interventions to prevent central venous line associated bloodstream infections in adult intensive care unit patients other than anti-microbial catheters...
June 26, 2017: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/28651859/dwell-time-and-risk-of-central-line-associated-bloodstream-infection-in-neonates
#3
Erica Sanderson, Kee Thai Yeo, Alex Yueping Wang, Ian Callander, Barbara Bajuk, Srinivas Bolisetty, Kei Lui
BACKGROUND: Umbilical venous catheters (UVC) or peripherally inserted central catheters (PICC), commonly used in high risk neonates, may have a threshold dwell time for subsequent increased risk of central line associated blood stream infection (CLABSI). AIM: To evaluate the CLABSI risks in neonates having either UVC, PICC or those having both sequentially. METHODS: Study included 3985 infants who had UVC or PICC inserted between 2007 and 2009 cared for in 10 regional Neonatal Intensive Care Units: 1392 having UVC only (Group 1), 1317 PICC only (Group 2) and 1276 both UVC and PICC (Group 3)...
June 23, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28439517/incidence-and-risk-factors-for-organ-space-infection-after-radiofrequency-assisted-hepatectomy-or-ablation-of-liver-tumors-in-a-single-center-more-than-meets-the-eye
#4
Ioannis Karavokyros, Stamatios Orfanos, Anastasios Angelou, Antonia Meropouli, Dimitrios Schizas, John Griniatsos, Emmanouil Pikoulis
INTRODUCTION: Surgical site infections (SSIs) and especially organ/space infection (O/SI) after resection or ablation of liver tumors are associated with increased morbidity and mortality. A secondary blood stream infection (BSI) is considered an O/SI but the exact prevalence is unknown. We aimed to investigate the incidence of O/SI and BSIs in a cohort of consecutive patients after liver resection or ablation, to seek for a possible connection between them and to search for potential risk factors...
2017: Frontiers in Surgery
https://www.readbyqxmd.com/read/28425261/central-line-associated-blood-stream-infections-characteristics-and-risk-factors-for-mortality-over-a-5-5-year-period
#5
Aynur Atilla, Zahide Doğanay, Hale Kefeli Çelik, Mehmet Derya Demirağ, Sırrı S Kiliç
BACKGROUND/AIM: Central line-associated bloodstream infections (CLABSIs) are associated with substantial morbidity and mortality and the infection rates vary in a wide range1397645907(high: 62.5%; low: 20%) in developing countries. We aimed to investigate the characteristics and the risk factors for mortality in patients with CLABSIs in intensive care units (ICUs) and provide the relevant data. MATERIALS AND METHODS: The electronic medical records database and file records obtained through active surveillance by an infection control committee of a hospital were screened to identify patients with CLABSIs hospitalized from January 2008 through July 2013...
April 18, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28368268/candida-blood-stream-infection-in-neonates-experience-from-a-tertiary-care-teaching-hospital-of-central-india
#6
Sriparna Basu Alam, Rajesh Kumar Mahfuz, Ragini Tilak Munirul Islam, Ashok Kumar Mondal
OBJECTIVE: To assess the epidemiology of neonatal Candida blood stream infection. METHODS: Medical records of neonates with Candida blood stream infection over five years (September 2010 to August 2015) were reviewed. Clinical details, species distribution and antifungal susceptibility were noted. RESULTS: 114 neonates developed Candida blood stream infection. Commonly isolated Candida species were C. tropicalis, C. albicans and C. parapsilosis...
March 29, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/28330584/central-line-associated-sepsis-in-children-receiving-parenteral-nutrition-in-oman
#7
Tawfiq T Al Lawati, Adawaiya Al Jamie, Nasra Al Mufarraji
Parenteral Nutrition (PN) is used when gut fails to provide complete nutrition. Central line Associate Blood Stream Infection (CLABSI) a major complication of this therapy. The objective of the study was to report the incidence of CLABSI and associated mortality in children receiving PN in the Royal Hospital and study the indication and duration of PN use. All children from the age of 0-48 months who received TPN outside NICU from the period between 1/1/2011 till 31/12/2014 were included. Data were retrieved from the hospital electronic data base...
March 16, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28321802/sepsis-risk-factors-in-infants-with-congenital-diaphragmatic-hernia
#8
Michaël Levy, Nolwenn Le Sache, Mostafa Mokhtari, Guy Fagherazzi, Gaelle Cuzon, Benjamin Bueno, Virginie Fouquet, Alexandra Benachi, Sergio Eleni Dit Trolli, Pierre Tissieres
BACKGROUND: Congenital diaphragmatic hernia (CDH) is a rare congenital anomaly and remains among the most challenging ICU-managed disease. Beside severe pulmonary hypertension, lung hypoplasia and major abdominal surgery, infective complications remain major determinants of outcome. However, the specific incidence of sepsis as well as associated risk factors is unknown. METHODS: This prospective, 4-year observational study took place in the pediatric intensive care and neonatal medicine department of the Paris South University Hospitals (Le Kremlin-Bicêtre, France), CDH national referral center and involved 62 neonates with CDH...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28283785/a-quality-improvement-initiative-to-reduce-central-line-infection-in-neonates-using-checklists
#9
Jacqueline E Taylor, Susan J McDonald, Arul Earnest, Jim Buttery, Bree Fusinato, Samantha Hovenden, Andrea Wallace, Kenneth Tan
Central line associated blood stream infections (CLABSI) are the most common complication of central catheters in neonates. These infections increase length of hospital stay, hospital costs and impact on mortality and morbidities. We performed a quasi-experimental study, over 24 months, utilising a pre-post design to determine the impact checklists had on central line infections. We introduced checklists for insertion, daily maintenance and procedural access based on the existing clinical guideline. Infections and compliance were monitored and reported back to the unit each month...
May 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28267981/healthcare-associated-infections-in-cardiac-surgery-patients-with-prolonged-intensive-care-unit-stay
#10
Michael Mazzeffi, James Gammie, Bradley Taylor, Sarah Cardillo, Nicholina Haldane-Lutterodt, Anthony Amoroso, Anthony Harris, Kerri Thom
BACKGROUND: Healthcare-associated infections (HAIs) are responsible for many deaths of hospitalized patients each year. Patients with prolonged hospitalization are at high risk for HAIs. Increased efforts have been made to decrease these infections, but a recent report from the Centers for Disease Control suggests that some HAIs may be increasing. We hypothesized that HAIs would remain frequent among cardiac surgery patients with prolonged intensive care unit stay and would be associated with increased mortality...
April 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28188037/determinants-of-outcomes-in-patients-with-simple-gastroschisis
#11
Fouad Youssef, Jean-Martin Laberge, Pramod Puligandla, Sherif Emil
PURPOSE: We analyzed the determinants of outcomes in simple gastroschisis (GS) not complicated by intestinal atresia, perforation, or necrosis. METHODS: All simple GS patients enrolled in a national prospective registry from 2005 to 2013 were studied. Patients below the median for total parenteral nutrition (TPN) duration (26days) and hospital stay (34days) were compared to those above. Univariate and multivariate logistic and linear regression analyses were employed using maternal, patient, postnatal, and treatment variables...
May 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28125827/do-clinicians-understand-quality-metric-data-an-evaluation-in-a-twitter-derived-sample
#12
Sushant Govindan, Vineet Chopra, Theodore J Iwashyna
OBJECTIVE: Despite significant efforts and cost, quality metrics do not consistently influence practice. While research has focused on improving data through statistical risk-adjustment, whether clinicians understand these data is unknown. Therefore, we assessed clinician comprehension of central line-associated blood stream infection (CLABSI) quality metric data. DESIGN: Cross-sectional survey with an 11-item test of CLABSI data comprehension. Each question assessed 1 of 3 concepts concerning CLABSI understanding: basic numeracy, risk-adjustment numeracy, and risk-adjustment interpretation...
January 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/28079867/reducing-peripherally-inserted-central-catheters-in-the-neonatal-intensive-care-unit
#13
A J Vachharajani, N A Vachharajani, H Morris, A Niesen, A Elward, D A Linck, A M Mathur
OBJECTIVE: Our objective was to safely reduce the number of peripherally inserted central catheters (PICCs) inserted in infants with umbilical venous catheter using quality improvement methods. STUDY DESIGN: In a tertiary neonatal intensive care unit, a questionnaire designed to prompt critical thinking around the decision to place a PICC, along with an updated standardized feeding guideline was introduced. PICC insertion in 86 infants with umbilical venous catheter (pre intervention) with birth weight 1000-1500 g were compared with 115 infants (post intervention) using Fisher's exact test...
April 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/27798663/epidemiology-of-blood-stream-infection-due-to-candida-species-in-a-tertiary-care-hospital-in-japan-over-12-years-importance-of-peripheral-line-associated-candidemia
#14
Masahiro Ishikane, Kayoko Hayakawa, Satoshi Kutsuna, Nozomi Takeshita, Norio Ohmagari
BACKGROUND: Candidemia is an important cause of mortality in healthcare settings. Peripheral lines are a source of candidemia, yet few studies have reported on the clinico-epidemiological features of candidemia due to peripheral-line associated blood stream infection (PLABSI). METHODS: We conducted a single-centre retrospective cohort study of all patients with candidemia between 2002 and 2013. PLABSI was defined as the presence of at least one of the following: the presence of phlebitis or the resolution of clinical symptoms after peripheral-line withdrawal, with careful exclusion of an alternative explanation for bacteraemia...
2016: PloS One
https://www.readbyqxmd.com/read/27730778/antibiotic-lock-therapy-in-the-era-of-gram-negative-resistance
#15
Rajeev Soman, Neha Gupta, Mitesh Suthar, Jatin Kothari, Alan Almeida, Anjali Shetty, Camilla Rodrigues
BACKGROUND: Central-line-associated blood-stream infection (CLABSI) is a highly consequential nosocomial infection. The most effective management includes the removal of the infected catheter. Retention of the catheter and antibiotic lock therapy (ALT) along with systemic antibiotics may be attempted only if there are unusual extenuating circumstances. CLABSIs due to Gram-negative bacteria (GNB) is more common in our setting and the organisms are often highly resistant. Hence, there is a need to explore the use of novel antimicrobials for catheter lock solutions along with antibiofilm agents...
February 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27618377/one-rural-hospital-s-experience-implementing-the-society-for-healthcare-epidemiology-of-america-guidelines-to-decrease-central-line-infections
#16
Maria H Curlej, Elizabeth Katrancha
In an effort to take advantage of the Highmark Quality Blue Initiative () requiring information from hospitals detailing their central line-associated blood stream infections (CLABSIs) surveillance system, quality improvement program, and statistics regarding the CLABSI events, this institution investigated the latest evidence-based recommendations to reduce CLABSIs. Recognizing the baseline rate of 2.4 CLABSIs per 1,000 central line days and its effect on patient outcomes and medical costs, this hospital made a commitment to improve their CLABSI outcomes...
September 2016: Journal of Trauma Nursing: the Official Journal of the Society of Trauma Nurses
https://www.readbyqxmd.com/read/27616655/risk-factors-for-bacteremia-and-central-line-associated-blood-stream-infections-in-children-with-acute-myelogenous-leukemia-a-single-institution-report
#17
COMPARATIVE STUDY
Ashley E J Rogers, Kristen M Eisenman, Susan A Dolan, Kristin M Belderson, Jocelyn R Zauche, Suhong Tong, Jane Gralla, Joanne M Hilden, Michael Wang, Kelly W Maloney, Samuel R Dominguez
BACKGROUND: Central line-associated blood stream infections (CLABSIs) are a source of high morbidity and mortality in children with acute myelogenous leukemia (AML). PROCEDURE: To understand the epidemiology and risk factors associated with the development of CLABSI in children with AML. METHODS: We retrospectively reviewed all patients with AML over a 5-year period between 2007 and 2011 at the Children's Hospital Colorado. Cases and controls were classified on the basis of the presence of a CLABSI as defined by the National Healthcare Safety Network...
March 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/27570854/prevalence-and-risk-factors-of-gram-negative-bacilli-causing-blood-stream-infection-in-patients-with-malignancy
#18
Fawzia E Al-Otaibi, Elham E Bukhari, Mona Badr, Abdulkarim A Alrabiaa
OBJECTIVES: To evaluate the epidemiology, risk factors, and antibiotic resistance of Gram negative bacteria (GNB) in patients with hematologic or solid organ malignancies.   METHODS: This is a retrospective study of 61 episodes of GNB bacteremia occurring in 56 patients with malignancy admitted to the Oncology Units in King Khalid University Hospital, Riyadh. Kingdom of Saudi Arabia during the period from January 2013 to October 2015. Data were retrieved from the computerized database of the microbiology laboratory and the patient's medical records...
September 2016: Saudi Medical Journal
https://www.readbyqxmd.com/read/27559470/a-project-to-reduce-the-rate-of-central-line-associated-bloodstream-infection-in-icu-patients-to-a-target-of-zero
#19
Muhammad Yaseen, Fahad Al-Hameed, Khalid Osman, Mansour Al-Janadi, Majid Al-Shamrani, Asim Al-Saedi, Abdulhakeem Al-Thaqafi
Central venous catheters (CVCs) are life-saving and the majority of patients in intensive care units (ICUs) have them placed in order to receive medicine and fluids. However, the use of these catheters can result in serious bloodstream infections. The rate of Central Line Associated Blood Stream Infection (CLABSI) in Adult Intensive Care Units (ICUs) at King Abdulaziz Medical City Jeddah (KAMC-J) at the start of the project was 2.0/1000 line days in 2008. The Central Line (CL) Bundle by the Institute of Healthcare Improvement (IHI) was implemented at the same time with monitoring of compliance to the CL Bundle...
2016: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/27484446/risk-factors-for-central-line-associated-bloodstream-infections
#20
Shilpa Tomar, Rakesh Lodha, Bimal Das, Seema Sood, Arti Kapil
OBJECTIVE: To carry out surveillance of central line associated bloodstream infections in a Pediatric intensive care unit (PICU) and determine associated risk factors. METHODS: This prospective study was conducted over 1.5 years in the PICU. CDC definitions for these infections were followed and associated risk factors were identified. RESULTS: Of 265 enrolled children with central line, 13 developed blood stream infections (incidence density 5...
September 8, 2016: Indian Pediatrics
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