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https://www.readbyqxmd.com/read/29140755/expression-of-concern
#1
(no author information available yet)
The Journal Editors hereby issue this note of an expression of concern for the following publication: Benjamin, A. J., Jr., Kepes, S., & Bushman, B. J. (2017). Effects of weapons on aggressive thoughts, angry feelings, hostile appraisals, and aggressive behavior: A meta-analytic review of the weapons effect literature. Personality and Social Psychology Review. Advance online publication. doi:10.1177/1088868317725419 The authors of this manuscript contacted the editors indicating they had discovered some errors in the computation of effect sizes in their meta-analysis...
November 1, 2017: Personality and Social Psychology Review
https://www.readbyqxmd.com/read/29138097/gastric-microbiota-an-emerging-player-in-helicobacter-pylori-induced-gastric-malignancies
#2
J Luis Espinoza, Ayumi Matsumoto, Hirokazu Tanaka, Itaru Matsumura
The complex diversity of nonpathogenic microbes that colonize the human body, known as microbiota, exert considerable effects on physiological homeostasis, and immune regulation. Helicobacter pylori (H. pylori) is a bacterium that frequently colonizes human stomach and is a major pathogenic agent for peptic ulcer diseases, gastric cancer, and mucosa-associated lymphoid tissue (MALT) lymphoma. Due to its acidic pH and peristaltic movements, the stomach has been considered a hostile environment for most microorganisms, however various commensal microorganisms are capable of colonizing the stomach to form a stomach niche...
November 11, 2017: Cancer Letters
https://www.readbyqxmd.com/read/29134588/encapsulation-strategies-of-bacteriophage-felix-o1-for-oral-therapeutic-application
#3
Golam S Islam, Qi Wang, Parviz M Sabour
Due to emerging antibiotic-resistant strains among the pathogens, a variety of strategies, including therapeutic application of bacteriophages, have been suggested as a possible alternative to antibiotics in food animal production. As pathogen-specific biocontrol agents, bacteriophages are being studied intensively. Primarily their applications in the food industry and animal production have been recognized in the USA and Europe, for pathogens including Salmonella, Campylobacter, Escherichia coli, and Listeria...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29132291/hiv-prevention-needs-for-men-who-have-sex-with-men-in-swaziland
#4
Bhekie Sithole
Men who have sex with men (MSM) have a high HIV burden and also often face multiple other challenges accessing HIV services, including legal and social issues. Although Swaziland recently started responding with interventions for MSM, significant gaps still exist both in information and programming. This study aimed to explore the HIV prevention needs of MSM in Swaziland, including factors elevating their risks and vulnerabilities to HIV infection; to find out what HIV prevention strategies exist; and to determine how best to meet the prevention needs of MSM...
December 2017: African Journal of AIDS Research: AJAR
https://www.readbyqxmd.com/read/29131873/longitudinal-trajectories-of-mental-health-in-australian-children-aged-4-5-to-14-15-years
#5
Daniel Christensen, Michael T Fahey, Rebecca Giallo, Kirsten J Hancock
Mental health can affect young people's sense of wellbeing and life satisfaction, their ability to participate in employment and education, and their onward opportunities in life. This paper offers a rare opportunity to longitudinally examine mental health in a population-representative study of children aged 4-5 years to 14-15 years. Using data from the Longitudinal Study of Australian Children (LSAC), this study examined maternally-reported child mental health over a 10 year period, in order to understand their initial mental health status early in life and its change over time, as measured by the Strengths and Difficulties Questionnaire...
2017: PloS One
https://www.readbyqxmd.com/read/29129690/monoterpenoid-perillyl-alcohol-impairs-metabolic-flexibility-of-candida-albicans-by-inhibiting-glyoxylate-cycle
#6
Moiz A Ansari, Zeeshan Fatima, Kamal Ahmad, Saif Hameed
The metabolic pathway such as glyoxylate cycle (GC) enables Candida albicans, to survive under glucose deficient conditions prevalent in the hostile niche. Thus its key enzymes (Isocitrate lyase; ICL and malate synthase; MLS) represent attractive targets against C. albicans. We have previously reported the antifungal potential of a natural monoterpenoid perillyl alcohol (PA). The present study uncovers additional role of PA as a potent GC inhibitor. We explored that PA phenocopied ICL1 deletion mutant and were hypersensitive under low carbon utilizing conditions...
November 9, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29129382/the-cryoelectron-microscopy-structure-of-the-type-1-chaperone-usher-pilus-rod
#7
Manuela K Hospenthal, Dawid Zyla, Tiago R D Costa, Adam Redzej, Christoph Giese, James Lillington, Rudi Glockshuber, Gabriel Waksman
Adhesive chaperone-usher pili are long, supramolecular protein fibers displayed on the surface of many bacterial pathogens. The type 1 and P pili of uropathogenic Escherichia coli (UPEC) play important roles during urinary tract colonization, mediating attachment to the bladder and kidney, respectively. The biomechanical properties of the helical pilus rods allow them to reversibly uncoil in response to flow-induced forces, allowing UPEC to retain a foothold in the unique and hostile environment of the urinary tract...
November 7, 2017: Structure
https://www.readbyqxmd.com/read/29128569/lysophosphatidic-acid-receptor-1-is-important-for-intestinal-epithelial-barrier-function-and-susceptibility-to-colitis
#8
Songbai Lin, Yiran Han, Kayte Jenkin, Sei-Jung Lee, Maiko Sasaki, Jan-Michael Klapproth, Peijian He, C Chris Yun
Intestinal epithelial cells form a barrier that is critical in protecting the host from the hostile luminal environment. Previously, we showed that lysophosphatidic acid receptor 1 (LPAR1) regulates proliferation of intestinal epithelial cells such that the absence of LPA1 mitigates epithelial wound healing process. This study provides evidence that LPA1 is important for the maintenance of epithelial barrier integrity. The epithelial permeability, determined by fluorescently labeled dextran flux and transepithelial resistance, is increased in Lpar1(-/-) (Lpa1(-/-)) mouse intestine...
November 8, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/29126022/the-impact-of-police-presence-on-angry-and-aggressive-driving
#9
Predrag Stanojević, Mark J M Sullman, Dragan Jovanović, Dragana Stanojević
An extensive body of research has found that angry and aggressive driving are both significantly related to crash involvement. There has also been a large body of research investigating the situational factors related to angry and aggressive driving, but one interesting question that has not yet been answered is whether the enforcement of traffic laws causes or reduces angry and aggressive driving. The independent region of Northern Kosovo represents a unique opportunity to investigate the impact of a lack of traffic enforcement on driving behaviour...
November 7, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29124568/pkng-supports-mycobacterial-adaptation-in-acidic-environment
#10
Ruchi Paroha, Rashmi Chourasia, Rajesh Mondal, Shivendra K Chaurasiya
Mycobacterium tuberculosis (Mtb), causative agent of human tuberculosis (TB), has the remarkable ability to adapt to the hostile environment inside host cells. Eleven eukaryotic like serine-threonine protein kinases (STPKs) are present in Mtb. Protein kinase G (PknG) has been shown to promote mycobacterial survival inside host cells. A homolog of PknG is also present in Mycobacterium smegmatis (MS), a fast grower, non-pathogenic mycobacterium. In the present study, we have analyzed the role of PknG in mycobacteria during exposure to acidic environment...
November 9, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/29122280/the-psychological-impact-of-external-fixation-using-the-ilizarov-or-orthofix-lrs-method-to-treat-tibial-osteomyelitis-with-a-bone-defect
#11
Alimujiang Abulaiti, Yilizati Yilihamu, Tayierjiang Yasheng, Yamuhanmode Alike, Aihemaitijiang Yusufu
OBJECTIVE: To examine the psychological impact of external fixation for a tibial bone defect due to osteomyelitis, and to compare the Orthofix limb reconstruction system (LRS) with the Ilizarov external fixator. MATERIALS AND METHODS: The SCL-90-R questionnaire was administered at four different time points (before surgery, while patients wore the external fixation device, when the device was removed, and two to three months after). The scores at the four time points were compared, as were the two different methods of external fixation (Orthofix LRS vs...
November 6, 2017: Injury
https://www.readbyqxmd.com/read/29121918/-no-generics-doctor-the-perspective-of-general-practitioners-in-two-french-regions
#12
Béatrice Riner, Adèle Bussy, Jeannie Hélène-Pelage, Nycrees Moueza, Sébastien Lamy, Philippe Carrère
BACKGROUND: Generic medicines are essential to controlling health expenditures. Their market share is still small in France. The discourse and practices of prescribers may play a major role in their use. The purpose of this study was to explore the knowledge, attitudes and practices of general practitioners (GPs) toward generic medicines in two French regions with the lowest penetration rate of these products. METHODS: An observational study was carried out from October 2015 to February 2016 in Guadeloupe and Martinique...
November 9, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29121811/evidence-for-two-levels-of-intimate-partner-violence-and-aggression-among-incarcerated-young-male-violent-offenders
#13
Anna-Kari Sjödin, Märta Wallinius, Eva Billstedt, Björn Hofvander, Thomas Nilsson
Furthering knowledge of the subset of incarcerated partner violent offenders distinguished by aggression, anger, and hostility is relevant, as these offenders are guilty of the more severe kinds of intimate partner violence (IPV). Our aim was to identify groups with different patterns of IPV among convicted young Swedish male offenders, using data from the Development of Aggressive Antisocial Behavior Study, including 171 young men (18-25 years) convicted of a violent crime. Cluster analysis was used to identify different clusters based on amount and severity of IPV in combination with measures of anger, hostility, aggression, and psychopathic personality traits...
November 1, 2017: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/29120411/alternative-polyadenylation-of-zeb1-promotes-its-translation-during-genotoxic-stress-in-pancreatic-cancer-cells
#14
Ilaria Passacantilli, Valentina Panzeri, Pamela Bielli, Donatella Farini, Emanuela Pilozzi, Gianfranco Delle Fave, Gabriele Capurso, Claudio Sette
Pancreatic ductal adenocarcinoma (PDAC) is characterized by extremely poor prognosis. The standard chemotherapeutic drug, gemcitabine, does not offer significant improvements for PDAC management due to the rapid acquisition of drug resistance by patients. Recent evidence indicates that epithelial-to-mesenchymal transition (EMT) of PDAC cells is strictly associated to early metastasization and resistance to chemotherapy. However, it is not exactly clear how EMT is related to drug resistance or how chemotherapy influences EMT...
November 9, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/29120275/ethnic-differences-in-psychosocial-factors-in-methadone-maintenance-hmong-versus-non-hmong
#15
Gavin Bart
Little is known about the characteristics of U.S.-based Asian populations undergoing methadone maintenance treatment for opioid use disorders. We evaluated psychosocial factors in 76 Hmong and 130 non-Hmong on methadone maintenance for at least two months in a single urban methadone maintenance clinic. Assessments included the Addiction Severity Index 5th Edition, the Symptom Checklist-90, and the Structured Clinical Interview for DSM-IV Axis I Disorders. The Hmong were older, predominately male, and on lower doses of methadone than the non-Hmong...
November 9, 2017: Journal of Ethnicity in Substance Abuse
https://www.readbyqxmd.com/read/29120199/are-we-in-crisis-national-mental-health-and-treatment-trends-in-college-counseling-centers
#16
Henry Xiao, Dever M Carney, Soo Jeong Youn, Rebecca A Janis, Louis G Castonguay, Jeffrey A Hayes, Benjamin D Locke
The current state of college student mental health is frequently labeled a "crisis," as the demand for services and severity of symptomatology have appeared to increase in recent decades. Nationally representative findings are presented from the Center for Collegiate Mental Health, a practice research network based in the United States, composed of more than 340 university and college counseling centers, in an effort to illuminate trends in symptom severity and patterns in treatment utilization for the campus treatment seeking population...
November 2017: Psychological Services
https://www.readbyqxmd.com/read/29120019/cellular-protection-mechanisms-that-minimise-accumulation-of-mutations-in-intestinal-tissue
#17
Jacco van Rheenen, Lotte Bruens
The epithelial lining of the intestine is constantly exposed to a hostile environment containing a mixture of gastric acids, consumed harmful substances and microbes. It is widely accepted that the intestine has multiple mechanisms to protect itself against tissue damage. Here, we review three cellular protection mechanisms that protect intestinal tissue against accumulation of somatic mutations: the conveyer belt-like structure, stem cell competition and crypt fusion. We highlight the events that can perturb these cellular protection mechanisms, and their impact on accumulation of new (oncogenic) mutations...
November 9, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29117202/oil-palm-monoculture-induces-drastic-erosion-of-an-amazonian-forest-mammal-fauna
#18
Ana Cristina Mendes-Oliveira, Carlos A Peres, Paula Cristina R de A Maués, Geovana Linhares Oliveira, Ivo G B Mineiro, Susanne L Silva de Maria, Renata C S Lima
Oil palm monoculture comprises one of the most financially attractive land-use options in tropical forests, but cropland suitability overlaps the distribution of many highly threatened vertebrate species. We investigated how forest mammals respond to a landscape mosaic, including mature oil palm plantations and primary forest patches in Eastern Amazonia. Using both line-transect censuses (LTC) and camera-trapping (CT), we quantified the general patterns of mammal community structure and attempted to identify both species life-history traits and the environmental and spatial covariates that govern species intolerance to oil palm monoculture...
2017: PloS One
https://www.readbyqxmd.com/read/29116642/the-relation-between-patient-characteristics-and-their-carers-use-of-a-directive-versus-collaborative-support-stance
#19
Josie Geller, Megumi Iyar, Suja Srikameswaran, Joanna Zelichowska, Yuan Zhou, Erin C Dunn
OBJECTIVES: Collaborative support provided by carers (family and friends) of individuals with eating disorders has been shown to be integral to patient motivation and clinical outcome. Little is known about factors that contribute to carers' use of collaborative, as opposed to directive, support stance. This exploratory research investigated associations between patient characteristics and carers' support beliefs and behaviors. METHOD: Eating disorder patients (n = 72) completed measures of readiness for change, eating disorder, and psychiatric symptom severity, and interpersonal functioning...
November 8, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/29113863/long-term-outcomes-after-carotid-artery-stenting-of-patients-with-prior-neck-irradiation-or-surgery
#20
Ho-Hin K Choy, Damianos G Kokkinidis, Ryan Cotter, Gagan D Singh, R Kevin Rogers, Stephen W Waldo, John R Laird, Ehrin J Armstrong
BACKGROUND: Carotid artery stenting (CAS) is often performed in patients with carotid artery stenosis who have relative contraindications to carotid endarterectomy (CEA), including hostile neck anatomy (e.g., history of neck irradiation or prior surgery). We examined the impact of hostile neck anatomy on long-term outcomes after CAS. METHODS: All carotid artery stent procedures performed at two institutions from 2006 to 2016 were reviewed. Routine duplex carotid ultrasound was used to assess target lesion restenosis at regular intervals...
September 21, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
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