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https://www.readbyqxmd.com/read/29793197/association-of-low-moderate-urine-arsenic-and-qt-interval-cross-sectional-and-longitudinal-evidence-from-the-strong-heart-study
#1
Katherine A Moon, Yiyi Zhang, Eliseo Guallar, Kevin A Francesconi, Walter Goessler, Jason G Umans, Lyle G Best, Barbara V Howard, Richard B Devereux, Peter M Okin, Ana Navas-Acien
Epidemiologic studies suggest that chronic exposure to arsenic is related to cardiovascular disease (CVD), but the pathophysiological link remains uncertain. We evaluated the association of chronic low-moderate arsenic exposure and arsenic metabolism with baseline difference and annual change in ECG measures (QT interval, JT interval, PR interval, QRS duration, and QT dispersion) using linear mixed models in the Strong Heart Study main cohort (N = 1174, median age 55 years) and family study (N = 1695 diabetes-free, median age 36 years)...
May 21, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29792925/change-in-patient-reported-outcomes-in-patients-with-and-without-mechanical-symptoms-undergoing-arthroscopic-meniscal-surgery-a-prospective-cohort-study
#2
Kenneth Pihl, Aleksandra Turkiewicz, Martin Englund, L Stefan Lohmander, Uffe Jørgensen, Nis Nissen, Jeppe Schjerning, Jonas B Thorlund
OBJECTIVE: Patients with degenerative or traumatic meniscal tears are at high risk of developing knee osteoarthritis. We investigated if younger (≤40 years) and older (>40 years) patients with preoperative mechanical symptoms improved more in patient-reported outcomes after meniscal surgery than those without mechanical symptoms. DESIGN: Patients from Knee Arthroscopy Cohort Southern Denmark (KACS) undergoing arthroscopic surgery for a meniscal tear completed online questionnaires before surgery, and at 12 and 52 weeks follow-up...
May 21, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29792238/mapping-the-neuroanatomic-substrates-of-cognition-in-familial-attention-deficit-hyperactivity-disorder
#3
Rachel Muster, Saadia Choudhury, Wendy Sharp, Steven Kasparek, Gustavo Sudre, Philip Shaw
BACKGROUND: While the neuroanatomic substrates of symptoms of attention deficit hyperactivity disorder (ADHD) have been investigated, less is known about the neuroanatomic correlates of cognitive abilities pertinent to the disorder, particularly in adults. Here we define the neuroanatomic correlates of key cognitive abilities and determine if there are associations with histories of psychostimulant medication. METHODS: We acquired neuroanatomic magnetic resonance imaging data from 264 members of 60 families (mean age 29...
May 24, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29791895/effect-of-postprandial-administration-of-esomeprazole-on-reflux-symptoms-in-gastroesophageal-reflux-disease-a-randomized-controlled-trial
#4
Doron Boltin, Ibrahim Zvidi, Maria Raskin, Hen Kayless, Hemda Schmilovitz-Weiss, Rachel Gingold-Belfer, Yaron Niv, Ram Dickman
BACKGROUND: Esomeprazole is commonly administered with food; however, clinical data to support this practice are lacking. We aimed to determine the effect of postprandial ingestion of esomeprazole on reflux symptoms among patients with gastroesophageal reflux disease (GERD). METHODS: Consecutive patients with GERD adequately controlled with esomeprazole 40 mg daily, entered a 2-week lead-in period during which esomeprazole was administered 30 min before breakfast...
May 23, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29791516/the-relevance-of-restrained-eating-behavior-for-circadian-eating-patterns-in-adolescents
#5
Stefanie A J Koch, Ute Alexy, Tanja Diederichs, Anette E Buyken, Sarah Roßbach
BACKGROUND: Restrained Eating, i.e. the tendency to restrict dietary intake to control body-weight, often emerges during adolescence and may result in changes in circadian eating patterns. OBJECTIVE: The objective of the present investigation was to determine the cross-sectional relevance of restrained eating for characteristics of circadian eating pattern in adolescents and whether changes in restrained eating are accompanied by concurrent changes in circadian eating pattern over the course of adolescence...
2018: PloS One
https://www.readbyqxmd.com/read/29791504/periconceptional-maternal-dairy-rich-dietary-pattern-is-associated-with-prenatal-cerebellar-growth
#6
Francesca Parisi, Melek Rousian, Irene V Koning, Sten P Willemsen, Jeanne H M de Vries, Eric A P Steegers, Régine P M Steegers-Theunissen
BACKGROUND: Maternal nutrition during pregnancy has been related to intrauterine brain development and neurodevelopmental disabilities in adult life. We aim to investigate associations between periconceptional maternal dietary patterns and prenatal cerebellar growth from the first trimester onwards. MATERIALS AND METHODS: 126 women with singleton non-malformed pregnancies were enrolled before 8 weeks of gestation in the Rotterdam periconceptional cohort between 2013 and 2015...
2018: PloS One
https://www.readbyqxmd.com/read/29791488/comparison-of-the-validity-of-smear-and-culture-conversion-as-a-prognostic-marker-of-treatment-outcome-in-patients-with-multidrug-resistant-tuberculosis
#7
Kefyalew Addis Alene, Kerri Viney, Hengzhong Yi, Emma S McBryde, Kunyun Yang, Liqiong Bai, Darren J Gray, Zuhui Xu, Archie C A Clements
BACKGROUND: The World Health Organization (WHO) has conditionally recommended the use of sputum smear microscopy and culture examination for the monitoring of multidrug-resistant tuberculosis (MDR-TB) treatment. We aimed to assess and compare the validity of smear and culture conversion at different time points during treatment for MDR-TB, as a prognostic marker for end-of-treatment outcomes. METHODS: We undertook a retrospective observational cohort study using data obtained from Hunan Chest Hospital, China and Gondar University Hospital, Ethiopia...
2018: PloS One
https://www.readbyqxmd.com/read/29790612/split-axilla-comparison-study-of-0-5-mhz-invasive-bipolar-radiofrequency-treatment-using-insulated-microneedle-electrodes-for-primary-axillary-hyperhidrosis
#8
S B Cho, J Park, Z Zheng, K H Yoo, H Kim
BACKGROUND: Energy-delivering devices can be used to induce thermal coagulation of the eccrine sweat glands for treating primary axillary hyperhidrosis (PAH). OBJECTIVE: The objective of this study was to compare the efficacy and safety of invasive, bipolar radiofrequency (RF) treatment for PAH. METHODS: A split-axilla study was performed to compare the clinical outcomes of 0.5 MHz, invasive, bipolar RF treatment with treatment settings of a longer conduction time and lower power (LC/LP) vs a shorter conduction time and higher power (SC/HP) for treating PAH...
May 23, 2018: Skin Research and Technology
https://www.readbyqxmd.com/read/29790073/effect-of-low-back-pain-risk-stratification-strategy-on-patient-outcomes-and-care-processes-the-match-randomized-trial-in-primary-care
#9
Dan Cherkin, Benjamin Balderson, Rob Wellman, Clarissa Hsu, Karen J Sherman, Sarah C Evers, Rene Hawkes, Andrea Cook, Martin D Levine, Diane Piekara, Pam Rock, Katherine Talbert Estlin, Georgie Brewer, Mark Jensen, Anne-Marie LaPorte, John Yeoman, Gail Sowden, Jonathan C Hill, Nadine E Foster
BACKGROUND: The STarT Back strategy for categorizing and treating patients with low back pain (LBP) improved patients' function while reducing costs in England. OBJECTIVE: This trial evaluated the effect of implementing an adaptation of this approach in a US setting. DESIGN: The Matching Appropriate Treatments to Consumer Healthcare needs (MATCH) trial was a pragmatic cluster randomized trial with a pre-intervention baseline period. Six primary care clinics were pair randomized, three to training in the STarT Back strategy and three to serve as controls...
May 22, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29789346/maternal-polycystic-ovarian-syndrome-and-offspring-growth-the-upstate-kids-study
#10
Griffith A Bell, Rajeshwari Sundaram, Sunni L Mumford, Hyojun Park, Miranda Broadney, James L Mills, Erin M Bell, Edwina H Yeung
BACKGROUND: Polycystic ovarian syndrome (PCOS) is the most common cause of female infertility and is associated with higher levels of circulating androgens. Exposure to higher levels of androgens in utero may be a risk factor for obesity among children of women with PCOS. METHODS: We examined whether maternal PCOS was associated with differences in offspring growth and obesity in the Upstate KIDS study, a prospective cohort study of infants born in New York State (excluding New York City) oversampled for fertility treatments and multiple births...
May 22, 2018: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/29789278/the-effectiveness-of-a-computer-tailored-e-learning-program-for-practice-nurses-to-improve-their-adherence-to-smoking-cessation-counseling-guidelines-randomized-controlled-trial
#11
Dennis de Ruijter, Math Candel, Eline Suzanne Smit, Hein de Vries, Ciska Hoving
BACKGROUND: Improving practice nurses' (PN) adherence to smoking cessation counseling guidelines will benefit the quality of smoking cessation care and will potentially lead to higher smoking abstinence rates. However, support programs to aid PNs in improving their guideline uptake and adherence do not exist yet. OBJECTIVE: The aim of this study was to assess the effects of a novel computer-tailored electronic learning (e-learning) program on PNs' smoking cessation guideline adherence...
May 22, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29789266/microvascular-volume-in-symptomatic-achilles-tendons-is-associated-with-visa-a-score
#12
S F E Praet, J H Ong, C Purdam, M Welvaert, G Lovell, L Dixon, J E Gaida, J Anglim, S Manzanero, N Vlahovich, D Hughes, G Waddington
OBJECTIVES: The role of neovascularisation in tendinopathy is still poorly understood, potentially due to technical limitations of conventional power Doppler ultrasound. This study aimed to investigate the association between contrast-enhanced ultrasound (CEUS) microvascular volume (MV), Victorian Institute of Sports Assessment-Achilles (VISA-A) scores and intrinsic Achilles tendon tenderness, as well as two different Power Doppler modes. DESIGN: Cross-sectional study...
May 15, 2018: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29789185/variation-in-post-thaw-sperm-quality-of-white-tailed-deer-bucks-odocoileus-virginianus-during-rut
#13
Jamie L Stewart, Clifford F Shipley, Robyn E Ellerbrock, Fabio S Lima, Igor F Canisso
White-tailed deer farming is a growing industry in the United States, with breeding operations contributing significantly to the industry's economic impact. Artificial insemination with frozen semen allows for selection and dissemination of valuable genetics, yet surprisingly little is known regarding the best time throughout rut to perform semen cryopreservation. The objective of this study was to compare semen quality following cryopreservation of white-tailed deer bucks collected early in the breeding season (September, n = 6), at peak rut (December, n = 8), and late season (March, n = 7)...
May 19, 2018: Animal Reproduction Science
https://www.readbyqxmd.com/read/29789099/building-capacity-for-change-evaluation-of-an-organisation-wide-leadership-development-program
#14
Tim Schultz, Jodie Shoobridge, Gill Harvey, Libby Carter, Alison Kitson
Objective. This study evaluated Leading 4 Change, a change leadership development program designed to support healthcare middle managers through a period of significant organisational change and enhance workplace resilience. Methods. A mixed methods evaluation was conducted within the program's framework of a quality improvement activity. Quantitative measures were participant responses (n=160) to online questionnaires, which were compared before and after the program, using an uncontrolled pre-post study design...
May 23, 2018: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/29788935/maternal-anemia-is-a-potential-risk-factor-for-anemia-in-children-aged-6-59-months-in-southern-africa-a-multilevel-analysis
#15
Peter A M Ntenda, Owen Nkoka, Paul Bass, Thomas Senghore
BACKGROUND: The effect of maternal anemia on childhood hemoglobin status has received little attention. Thus, we examined the potential association between maternal anemia and childhood anemia (aged 6-59 months) from selected Southern Africa countries. METHODS: A cross-sectional study using nationally representative samples of children aged 6-59 months from the 2010 Malawi, 2011 Mozambique, 2013 Namibia, and 2010-11 Zimbabwe demographic and health surveys (DHS) was conducted...
May 22, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29788542/accuracy-of-visual-inspection-performed-by-community-health-workers-in-cervical-cancer-screening
#16
REVIEW
Susan D Driscoll, Ruth M Tappen, David Newman, Kathi Voege-Harvey
BACKGROUND: Cervical cancer remains the leading cause of cancer and mortality in low-resource areas with healthcare personnel shortages. Visual inspection is a low-resource alternative method of cervical cancer screening in areas with limited access to healthcare. OBJECTIVES: To assess accuracy of visual inspection performed by community health workers (CHWs) and licensed providers, and the effect of provider training on visual inspection accuracy. SEARCH STRATEGY: Five databases and four websites were queried for studies published in English up to December 31, 2015...
May 22, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29788458/are-globals-for-health-well-being-and-quality-of-life-interchangeable-a-mixed-methods-study-in-ankylosing-spondylitis-patients-and-controls
#17
Astrid van Tubergen, Anouk Gulpen, Robert Landewé, Annelies Boonen
Objective: Patients' experience of overall health is often assessed through a single-item global question. Here, we evaluated among patients with AS and population controls whether single-item questions on the constructs health, well-being and quality of life (QoL) are interchangeable. Methods: In a mixed quantitative and qualitative approach, all subjects scored the three single-item globals on a numeric rating scale (0-10, best). Next, they indicated for each of the questions which aspects they had been considering when scoring...
May 19, 2018: Rheumatology
https://www.readbyqxmd.com/read/29788083/evaluation-of-an-intensive-interdisciplinary-pain-treatment-based-on-acceptance-and-commitment-therapy-for-adolescents-with-chronic-pain-and-their-parents-a-nonrandomized-clinical-trial
#18
Mike K Kemani, Marie Kanstrup, Abbie Jordan, Line Caes, Jeremy Gauntlett-Gilbert
Objective: Parental factors are central in the development and maintenance of chronic pain in youths. Only a handful of studies have investigated the impact of psychological treatments for pediatric chronic pain on parental factors, and the relationships between changes in parental and adolescent factors. In the current study, we evaluated the effects of an intensive interdisciplinary pain treatment (IIPT) program based on Acceptance and Commitment Therapy (ACT) for adolescents with chronic pain, on adolescent and parental variables, and the relationship between parental psychological flexibility and adolescent pain acceptance...
May 17, 2018: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29788038/testing-a-longitudinal-compensation-model-in-premanifest-huntington-s-disease
#19
Sarah Gregory, Jeffrey D Long, Stefan Klöppel, Adeel Razi, Elisa Scheller, Lora Minkova, Eileanoir B Johnson, Alexandra Durr, Raymund A C Roos, Blair R Leavitt, James A Mills, Julie C Stout, Rachael I Scahill, Sarah J Tabrizi, Geraint Rees
The initial stages of neurodegeneration are commonly marked by normal levels of cognitive and motor performance despite the presence of structural brain pathology. Compensation is widely assumed to account for this preserved behaviour, but despite the apparent simplicity of such a concept, it has proven incredibly difficult to demonstrate such a phenomenon and distinguish it from disease-related pathology. Recently, we developed a model of compensation whereby brain activation, behaviour and pathology, components key to understanding compensation, have specific longitudinal trajectories over three phases of progression...
May 17, 2018: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29787891/development-of-postural-control-in-infancy-in-cerebral-palsy-and-cystic-periventricular-leukomalacia
#20
Anke G Boxum, Linze-Jaap Dijkstra, Sacha la Bastide-van Gemert, Elisa G Hamer, Tjitske Hielkema, Heleen A Reinders-Messelink, Mijna Hadders-Algra
BACKGROUND: Development of postural problems in Cerebral Palsy (CP) is largely unknown. Postural muscle activity is organized into two levels: 1) direction-specificity; 2) fine-tuning of direction-specific activity. AIM: To study development of postural control until 21 months corrected age in subgroups of infants at very high-risk (VHR) of CP: a) with and without CP at 21 months; b) with and without cystic periventricular leukomalacia (cPVL), the brain lesion with highest risk of CP...
May 19, 2018: Research in Developmental Disabilities
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