Donghee Han, Andrew Lin, Keiichiro Kuronuma, Evangelos Tzolos, Alan C Kwan, Eyal Klein, Daniele Andreini, Jeroen J Bax, Filippo Cademartiri, Kavitha Chinnaiyan, Benjamin J W Chow, Edoardo Conte, Ricardo C Cury, Gudrun Feuchtner, Martin Hadamitzky, Yong-Jin Kim, Jonathon A Leipsic, Erica Maffei, Hugo Marques, Fabian Plank, Gianluca Pontone, Todd C Villines, Mouaz H Al-Mallah, Pedro de Araújo Gonçalves, Ibrahim Danad, Heidi Gransar, Yao Lu, Ji-Hyun Lee, Sang-Eun Lee, Lohendran Baskaran, Subhi J Al'Aref, Yeonyee E Yoon, Alexander Van Rosendael, Matthew J Budoff, Habib Samady, Peter H Stone, Renu Virmani, Stephan Achenbach, Jagat Narula, Hyuk-Jae Chang, James K Min, Fay Y Lin, Leslee J Shaw, Piotr J Slomka, Damini Dey, Daniel S Berman
IMPORTANCE: Distinct plaque locations and vessel geometric features predispose to altered coronary flow hemodynamics. The association between these lesion-level characteristics assessed by coronary computed tomographic angiography (CCTA) and risk of future acute coronary syndrome (ACS) is unknown. OBJECTIVE: To examine whether CCTA-derived adverse geometric characteristics (AGCs) of coronary lesions describing location and vessel geometry add to plaque morphology and burden for identifying culprit lesion precursors associated with future ACS...
March 1, 2022: JAMA Cardiology