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https://www.readbyqxmd.com/read/28737932/ins-and-outs-in-environmental-and-occupational-safety-studies-of-asthma-and-engineered-nanomaterials
#1
Marina A Dobrovolskaia, Michael R Shurin, Valerian E Kagan, Anna A Shvedova
According to the Centers for Disease Control and Prevention, approximately 25 million Americans suffer from asthma. The disease total annual cost is about $56 billion and includes both the direct and indirect costs of medications, hospital stays, missed work, and decreased productivity. Air pollution with xenobiotics, bacterial agents, and industrial nanomaterials, such as carbon nanotubes, contribute to the exacerbation of this condition and are a point of particular attention in environmental toxicology as well as in occupational health and safety research...
July 24, 2017: ACS Nano
https://www.readbyqxmd.com/read/28735331/evaluation-of-the-levels-and-quality-of-microbial-contamination-in-medical-emergency-departments-in-comparison-to-other-workplaces
#2
Agata Bielawska-Drózd, Bożena Wlizło-Skowronek, Piotr Cieślik, Izabela Winnicka, Ewa Skopińska-Różewska, Leszek Kubiak, Dorota Żakowska, Aleksandra Brewczyńska, Janusz Kocik
Work in Hospital Emergency Departments (HEDs) exposes both the emergency ward staff and patients to infectious and in other way harmful biological agents. The results of this study shows the presence of pathogenic bacteria isolated by three different methods. It revealed 9.8% of pathogens detected by imprint method, 10.5% of pathogens by swabbing method, 17.6% and 22% in HEDs corridors and rooms, respectively, by air sampling method. In control workplaces (offices) pathogenic bacteria reached the level of 6...
January 2, 2017: Polish Journal of Microbiology
https://www.readbyqxmd.com/read/28728715/robotic-lobectomy-and-segmentectomy-technical-details-and-results
#3
REVIEW
Benjamin Wei, Robert J Cerfolio
Robotic-assisted pulmonary lobectomy can be considered for patients fit for conventional lobectomy. Contraindications include prohibitive lung function or medical comorbidities, multistation N2, gross N2 disease, or evidence of N3 disease. Team training, familiarity with equipment, troubleshooting, and preparation are critical for successful robotic lobectomy. Similar to video-assisted thoracoscopic surgery (VATS) lobectomy, robotic lobectomy is associated with decreased blood loss, blood transfusion, air leak, chest tube duration, duration of stay, and mortality compared with thoracotomy...
August 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28728621/high-flow-heated-humidified-air-via-nasal-cannula-treats-cpap-intolerant-children-with-obstructive-sleep-apnea
#4
Stephen Hawkins, Stephanie Huston, Kristen Campbell, Ann Halbower
STUDY OBJECTIVES: Continuous positive airway pressure (CPAP) is effective but challenging for children with obstructive sleep apnea (OSA). High-flow air via open nasal cannula (HFNC) as treatment in children remains controversial. We report the efficacy of HFNC in children with OSA and CPAP intolerance, a titration protocol, and a discussion of potential mechanisms. METHODS: Patients aged 1 to 18 years with OSA (defined by obstructive apnea-hypopnea index [OAHI] greater than 1 event/h) and CPAP intolerance were enrolled...
July 14, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28725909/skeletal-fluorosis-due-to-fluorocarbon-inhalation-from-an-air-dust-cleaner
#5
Katherine Peicher, Naim M Maalouf
Skeletal fluorosis (SF) is an osteosclerotic metabolic bone disorder caused by excessive ingestion or inhalation of fluoride. SF is extremely rare in developed countries. We report a case of SF due to inhalational abuse from a fluoride-containing air dust cleaner. A 33-year-old man with no past medical history presented with progressively worsening low back pain for 2 years. Physical examination was notable for loss of lumbar lordosis and tenderness over the lumbar spine. Radiographs were notable for uniform generalized osteosclerosis in the long bones, entire spine, rib cage, and pelvic bones, and loss of the normal lumbar curvature...
July 20, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28725312/two-cases-of-pneumatosis-cystoides-intestinalis-with-intraperitoneal-free-air
#6
Kensuke Wada, Nobuhiro Takeuchi, Masakazu Emori, Masanori Takada, Yusuke Nomura, Akihito Otsuka
Intraperitoneal free air (IFA) is sometimes accompanied by pneumatosis cystoides intestinalis (PCI); therefore, proper diagnosis is essential for PCI management. We report two cases of PCI with IFA. A 70-year-old female taking anti-psychotic medication for schizophrenia presented with repeated vomiting and high-grade fever. Computed tomography revealed small, linear gaseous cysts in the intestinal wall along with IFA. Although there was no sign of peritoneal irritation, intestinal perforation was not excluded...
June 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28724142/the-aging-physician-and-the-medical-profession-a-review
#7
E Patchen Dellinger, Carlos A Pellegrini, Thomas H Gallagher
Importance: The issue of the aging physician and when to cease practice has been controversial for many years. There are reports of prominent physicians who practiced after becoming dangerous in old age, but the profession has not demonstrated the ability to prevent this. A mandatory retirement age could be discriminatory and take many competent physicians out of practice and risk a physician shortage. An increasing body of evidence regarding the relationship between physicians' age and performance has led organizations, such as the American College of Surgeons, to revisit this challenge...
July 19, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28723769/overlooked-diagnosis-of-infected-paratracheal-air-cysts-in-patients-with-respiratory-symptoms-case-report
#8
Kyungsoo Bae, Kyung N Jeon, Mi J Park, Seung J Lee, Ho C Kim, Seung I Cha, Joung H Byun, Jong W Kim
RATIONALE: Infected paratracheal air cysts as the focus of respiratory symptoms can be overlooked in practice because of nonspecific symptoms and physician's scant knowledge for this entity. We report 2 cases of infected paratracheal air cyst diagnosed at chest computed tomography (CT) and bronchoscopy/endobronchial ultrasound. PATIENT CONCERN: Two patients visited our hospital with respiratory symptoms, including cough, sputum, and fever. DIAGNOSES: Chest CT showed paratracheal cystic lesions with air-fluid level in the thoracic inlet...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28720185/statin-therapy-in-low-risk-air-force-aviators-with-isolated-hypercholesterolemia
#9
Anthony P Tvaryanas, Heather J Mahaney, Valarie M Schroeder, Genny M Maupin
INTRODUCTION: This study evaluated the use of statin therapy in U.S. Air Force (USAF) aviators with isolated hypercholesterolemia in terms of compliance with clinical practice guidelines (CPGs) and effectiveness in reducing low-density lipoprotein cholesterol (LDL-C) and coronary heart disease (CHD) risk. METHODS: This was a mixed design, 8-yr retrospective study that included 8185 participants with isolated hypercholesterolemia, of which 1458 (17.81%) were prescribed statin monotherapy...
August 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28719404/predictive-factors-for-hearing-outcomes-after-canaloplasty-in-patients-with-congenital-aural-atresia
#10
Jungmin Ahn, Sun Young Baek, Kyunga Kim, Yang-Sun Cho
OBJECTIVE: The aim of this study was to determine the most important factors in preoperative imaging, including components of Jahrsdoefer score (J score), and favorable prognostic factors for postoperative hearing results after canaloplasty for congenital aural atresia. STUDY DESIGN: Retrospective review of medical records. SETTING, PATIENTS, INTERVENTION, MAIN OUTCOME MEASURE: One hundred eight patients who underwent canaloplasty by a single surgeon between January 2011 and July 2014 were included...
July 17, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28717826/operator-radiation-exposure-during-transradial-coronary-angiography-effect-of-single-vs-double-catheters
#11
A Tarighatnia, L Pourafkari, A Farajollahi, A H Mohammadalian, M Ghojazadeh, N D Nader
BACKGROUND: The right radial artery has gained popularity as the preferred access site for coronary angiography. To save time and limit the radiation exposure of operators and patients, newly designed catheters can be used to access both the right and left coronary arteries. The aim of this study was to compare operator radiation exposure between single-catheter (SCA) and two-catheter approaches (TCA). METHODS: In all, 256 patients undergoing diagnostic coronary angiography via the right radial artery in a high-volume medical center were randomized to either the SCA or TCA group...
July 17, 2017: Herz
https://www.readbyqxmd.com/read/28713086/intensifying-approach-to-the-therapy-of-patients-with-constellation-of-the-diseases-chronic-obstructive-pulmonary-disease-and-osteoarthritis
#12
Vyacheslav N Zhdan, Maksim М Potyazhenko, Galina S Khaymenova, Nadezhda N Lyulka, Tatyana V Dubrovinskaya, Igor V Ivanitsky
INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is one of 21st century. About 210 million people all over the world are suffering with COPD, and annually 3 million people die of it. Under the influence of different factors, such as smoking, air prolusion, evaporation of chemicals, poisoning effect of chemical firings, inflammation processes take place in lungs, and if it is prolonged and take place simultaneously with morphological changes in the lungs, it it provide the de4velopment of the systemic inflammation process...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28712959/associations-between-long-term-exposure-to-air-pollution-glycosylated-hemoglobin-and-diabetes
#13
Trenton Honda, Vivian C Pun, Justin Manjourides, Helen Suh
BACKGROUND: Air pollution exposures have been shown to adversely impact health through a number of biological pathways associated with glucose metabolism. However, few studies have evaluated the associations between air pollution and glycosylated hemoglobin (HbA1c) levels. Further, no studies have evaluated these associations in US populations or investigated whether associations differ in diabetic as compared to non-diabetic populations. To address this knowledge gap, we investigated the associations between airborne fine particulate matter (PM2...
June 26, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28710612/-diagnostic-quality-of-triage-algorithms-for-mass-casualty-incidents
#14
A R Heller, N Salvador, M Frank, J Schiffner, R Kipke, C Kleber
BACKGROUND: Regarding survival and quality of life, recent mass casualty incidents have once more emphasized the importance of early identification of the correct degree of injury or illness, to enable prioritizing treatment of patients and transportation to an appropriate hospital. The present study investigated international triage algorithms in terms of sensitivity (SE) and specificity (SP) as well as the process duration in a relevant emergency patient cohort. METHODS: A total of 500 consecutive air rescue missions were evaluated by means of standardized patient records...
July 14, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/28709967/advances-in-asthma-2016-designing-individualized-approaches-to-management
#15
William C Anderson, Andrea Apter, Cullen M Dutmer, Daniel A Searing, Stanley J Szefler
In this years Advances in Asthma review we discuss viral infections in asthma and potential therapeutic agents, the microbiome, novel genetic associations with asthma, air quality and climate effects on asthma, exposures during development and long term sequelae of childhood asthma, patient centered outcome research, and precision medicine. In addition, we discuss application of biomarkers to precision medicine, and new information on asthma medications. New evidence indicates that rhinovirus-triggered asthma exacerbations become more severe as the degree of sensitization to dust mite and mouse increase...
July 11, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28708814/chirp-evoked-otoacoustic-emissions-and-middle-ear-absorbance-for-monitoring-ototoxicity-in-cystic-fibrosis-patients
#16
Angela C Garinis, Douglas H Keefe, Lisa L Hunter, Denis F Fitzpatrick, Daniel B Putterman, Garnett P McMillan, Jeffrey A Gold, M Patrick Feeney
OBJECTIVES: The goal of this study was to investigate the use of transient-evoked otoacoustic emissions (TEOAEs) and middle ear absorbance measurements to monitor auditory function in patients with cystic fibrosis (CF) receiving ototoxic medications. TEOAEs were elicited with a chirp stimulus using an extended bandwidth (0.71 to 8 kHz) to measure cochlear function at higher frequencies than traditional TEOAEs. Absorbance over a wide bandwidth (0.25 to 8 kHz) provides information on middle ear function...
July 13, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28705430/effect-of-long-term-exposure-to-air-pollution-on-anxiety-and-depression-in-adults-a-cross-sectional-study
#17
Cristina Vert, Gonzalo Sánchez-Benavides, David Martínez, Xavier Gotsens, Nina Gramunt, Marta Cirach, José Luis Molinuevo, Jordi Sunyer, Mark J Nieuwenhuijsen, Marta Crous-Bou, Mireia Gascon
BACKGROUND: The association between exposure to air pollutants and mental disorders among adults has been suggested, although results are not consistent. OBJECTIVE: To analyze the association between long-term exposure to air pollution and history of anxiety and depression disorders and of medication use (benzodiazepines and antidepressants) in adults living in Barcelona. METHODS: A total of 958 adults (45-74 years old) residents in Barcelona, most of them having at least one of their parents diagnosed with dementia (86%), and participating in the ALFA (Alzheimer and Families) study, were included...
July 3, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28705149/f-treegc-a-questionnaire-based-family-tree-creation-software-for-genetic-counseling-and-genome-cohort-studies
#18
RANDOMIZED CONTROLLED TRIAL
Tomoharu Tokutomi, Akimune Fukushima, Kayono Yamamoto, Yasushi Bansho, Tsuyoshi Hachiya, Atsushi Shimizu
BACKGROUND: The Tohoku Medical Megabank project aims to create a next-generation personalized healthcare system by conducting large-scale genome-cohort studies involving three generations of local residents in the areas affected by the Great East Japan Earthquake. We collected medical and genomic information for developing a biobank to be used for this healthcare system. We designed a questionnaire-based pedigree-creation software program named "f-treeGC," which enables even less experienced medical practitioners to accurately and rapidly collect family health history and create pedigree charts...
July 14, 2017: BMC Medical Genetics
https://www.readbyqxmd.com/read/28704070/geographic-variation-in-mentally-unhealthy-days-air-pollution-and-altitude-perspectives
#19
Hoehun Ha
Ha, H. Geographic variation in mentally unhealthy days: air pollution and altitude perspectives. High Alt Med Biol 00:000-000, 2017.- Background: Mental health incorporates our emotional, psychological, and social well-being and it is critical at each phase of life, from youth and preadulthood through adulthood. METHODS: We assessed the association between mentally unhealthy days (MUDs), air pollutant concentrations, and altitude on the basis of cross-county studies. Data on poor mental health days for the United States were based on health-related telephone surveys conducted by the Behavioral Risk Factor Surveillance System (BRFSS)...
July 13, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28702305/increased-risk-of-pneumonia-in-residents-living-near-poultry-farms-does-the-upper-respiratory-tract-microbiota-play-a-role
#20
Lidwien A M Smit, Gert Jan Boender, Wouter A A de Steenhuijsen Piters, Thomas J Hagenaars, Elisabeth G W Huijskens, John W A Rossen, Marion Koopmans, Gonnie Nodelijk, Elisabeth A M Sanders, Joris Yzermans, Debby Bogaert, Dick Heederik
BACKGROUND: Air pollution has been shown to increase the susceptibility to community-acquired pneumonia (CAP). Previously, we observed an increased incidence of CAP in adults living within 1 km from poultry farms, potentially related to particulate matter and endotoxin emissions. We aim to confirm the increased risk of CAP near poultry farms by refined spatial analyses, and we hypothesize that the oropharyngeal microbiota composition in CAP patients may be associated with residential proximity to poultry farms...
2017: Pneumonia
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