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Post-isometric relaxation

Gokcen Telli, Yasemin Erac, Banu Cahide Tel, Bulent Gumusel
Adrenomedullin 2/intermedin (AM2/IMD) is a member of calcitonin related gene peptide family and an important nitric oxide mediated vasorelaxant in various vascular beds. However, the mechanism of post receptor-interaction is not clear and may differ depending on tissue type and species. In this study, we aimed to investigate the exact mechanism and the role of BKCa and calcium channels on the vasorelaxant effect of AM2/IMD in rat PA. Changes in the AM2/IMD-mediated vasorelaxation were evaluated in the presence of various inhibitors...
March 24, 2018: Peptides
M S Mazaev, V A Malchevskiy, N Y Prokopev, D A Khrupa
AIM: The objective of the present study was to evaluate the outcome the application of the technique for the post-isometric relaxation of the muscles of the lumbosacral region of the spine and of the lumbosacral junction as a component of the combined rehabilitation on the manifestations of the flexion contracture in the hip joint in the men at the age of 50-60 years following amputation of the lower limb at the hip level throughout the course of the rehabilitative process. MATERIALS AND METHODS: A total of 243 patients who had undergone ablation of a femur available for the examination...
December 28, 2017: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
Maryam Goudarzian, Samira Ghavi, Ardalan Shariat, Hossein Shirvani, Mostafa Rahimi
This study was designed to evaluate the effects of whole body vibration (WBV) exercise, mental training (MT), and the concurrent effect of WBV and MT on lower body balance, neuromuscular performance, and leg muscle strength in elderly men. In a randomized control trial study with parallel group design, 42 older men (mean±standard deviation age, 68±5.78 years) were randomly divided into four groups: WBV (n=11), MT (n=12), WBV+MT (n=10), and control (n=9) groups. The protocol of training consisted of three sessions per week for 8 weeks and about 30 min for each session...
October 2017: Journal of Exercise Rehabilitation
Trevor J Allen, Tyson Jones, Anthony Tsay, David L Morgan, Uwe Proske
Isometric exercise is often prescribed during rehabilitation from injury to maintain muscle condition and prevent disuse atrophy. However, such exercise can lead to muscle soreness and damage. Here we investigate which parameters of isometric contractions are responsible for the damage. Bouts of 30 repetitions of maximum voluntary contractions of elbow flexors in 38 subjects were carried out and peak force, soreness, and tenderness were measured before the exercise, immediately afterwards, at 2 h, and at 24 h postexercise...
February 1, 2018: Journal of Applied Physiology
Jianyou Zhang, Hui Liu, Shitong Li, Jin Wu, Jianhong Sun
The present study aimed to investigate the effects of acute sepsis on diaphragm contractility and relaxation, via examining the Ca2+‑uptake function of sarco/endoplasmic reticulum Ca2+ adenosine triphosphatase (SERCA), and the protein levels of SERCA1, SERCA2 and the ryanodine receptor (RyR) of the sarcoplasmic reticulum (SR). A sepsis rat model was established through cecal ligation and puncture (CLP). A total of 6 and 12 h following CLP, the isometric contractile and relaxation parameters of the diaphragm were measured...
October 2017: Molecular Medicine Reports
Sumiaki Maeo, Yukino Ando, Hiroaki Kanehisa, Yasuo Kawakami
We investigated localization of damage within the knee extensors (KEs) and plantar flexors (PFs) induced by downhill running (DR) by using transverse relaxation time (T2)-weighted magnetic resonance imaging (MRI). Fourteen young adults performed 45-min DR (-15% slope) at their maximal tolerable velocity. At pre- and 24, 48, and 72 h post-exercise, T2-MRI was scanned and T2 values for each muscle composing KEs and PFs at proximal, middle, and distal sites were calculated. Maximal isometric torque and rate of torque development (RTD: 0-30, 0-50, 0-100, 0-200 ms) were also measured...
July 18, 2017: Scientific Reports
Ian C Smith, Rene Vandenboom, A Russell Tupling
Repeated stimulation of unfatigued rodent fast-twitch skeletal muscle accelerates the kinetics of tension relaxation through an unknown mechanism. This effect varies with muscle type and stimulation parameters, and has been observed at physiological temperatures for submaximal but not maximal contractions. The purpose of this study was to compare relaxation kinetics of C57BL/6 mouse lumbrical muscles ex vivo from maximal isometric force (500 Hz for 20 ms) when evoked before (pre) and after (post) an intervening tetanic contraction at 37°C...
August 15, 2017: Journal of Experimental Biology
Rebecca Louise Jones, Cleveland Thomas Barnett, Joel Davidson, Billy Maritza, William D Fraser, Roger Harris, Craig Sale
PURPOSE: In fresh muscle, supplementation with the rate-limiting precursor of carnosine, β-alanine (BA), results in a decline in muscle half-relaxation time (HRT) potentially via alterations to calcium (Ca2+ ) handling. Accumulation of hydrogen cation (H+ ) has been shown to impact Ca2+ signalling during muscular contraction, carnosine has the potential to serve as a cytoplasmic regulator of Ca2+ and H+ coupling, since it binds to both ions. The present study examined the effect of BA supplementation on intrinsic in-vivo isometric knee extensor force production and muscle contractility in both fresh and fatigued human skeletal muscle assessed during voluntary and electrically evoked (nerve and superficial muscle stimulation) contractions...
May 2017: European Journal of Applied Physiology
S Maeo, A Saito, S Otsuka, X Shan, H Kanehisa, Y Kawakami
This study examined localization of muscle damage within the quadriceps femoris induced by different types of eccentric exercises by using transverse relaxation time (T2 )-weighted magnetic resonance imaging (MRI). Thirty-three young males performed either of the following three exercises: single-joint eccentric contraction of the knee extensors (KE), eccentric squat (S), or downhill walking (DW) (n=11/exercise). KE and S consisted of 5-set×10-lowering of 90% one-repetition maximum load. DW was performed for 60 minutes with -10% slope, 6 km/h velocity, and 20% body mass load carried...
January 2018: Scandinavian Journal of Medicine & Science in Sports
Matti Munukka, Benjamin Waller, Arja Häkkinen, Miika T Nieminen, Eveliina Lammentausta, Urho M Kujala, Juha Paloneva, Hannu Kautiainen, Ilkka Kiviranta, Ari Heinonen
PURPOSE: To study the relationship between 12-month leisure-time physical activity (LTPA) level and changes in estimated biochemical composition of tibiofemoral cartilage in postmenopausal women with mild knee osteoarthritis (OA). METHODS: Originally, 87 volunteer postmenopausal women, age 60 to 68 yr, with mild knee OA (Kellgren Lawrence I/II and knee pain) participated in a randomized controlled, 4-month aquatic training trial (RCT), after which 76 completed the 12-month postintervention follow-up period...
July 2017: Medicine and Science in Sports and Exercise
Carla Silva-Batista, Daniel Montie Corcos, Renato Barroso, Fabian J David, Hélcio Kanegusuku, Cláudia Forjaz, Marco Túlio DE Mello, Hamilton Roschel, Valmor Tricoli, Carlos Ugrinowitsch
PURPOSE: This study compared the effects of resistance training (RT) and RT with instability (RTI) on neuromuscular and total training volume (TTV) outcomes obtained as part of the Instability Resistance Training Trial in Parkinson's disease. It also used a linear multiple regression (forward stepwise method) to identify the contribution of neuromuscular outcomes to previously published improvements in the timed-up-and-go test and the Unified Parkinson's Disease Rating Scale, motor subscale score...
April 2017: Medicine and Science in Sports and Exercise
Eisuke Ochi, Yosuke Tsuchiya, Kazunori Nosaka
PURPOSE: This study compared maximal eccentric (ECC) and concentric (CON) contractions of the elbow flexors for changes in transverse relaxation time (T2) and indirect markers of muscle damage. METHODS: Twelve young men performed five sets of six maximal isokinetic (30°/s) ECC with one arm followed by CON with the other arm. Magnetic resonance images to assess T2 and cross-sectional area (CSA) of biceps brachii, brachialis, and brachioradialis, and measurements of maximal voluntary isometric contraction (MVC) torque, range of motion (ROM), and muscle soreness were taken before, immediately after, and 1, 3, and 5 days after each exercise...
December 2016: European Journal of Applied Physiology
Erol Çakmak, Özlem Yönem, Bülent Saraç, Mesut Parlak, Cumali Çelik, Hilmi Ataseven, İhsan Bağcivan
BACKGROUND: Relaxing the sphincter of Oddi (SO) is an important process during endoscopic retrograde cholangiopancreatography (ERCP) procedures. This issue suggests that the easier the sphincterotomy and cannulation, the more post-ERCP complications decrease. AIMS: To compare the relaxant effects of ataciguat (a novel soluble guanylyl cyclase activator) and zaprinast (an inhibitor of phosphodiesterase 5) on sheep SO in vitro, thus testing whether they can be used during ERCP...
July 2016: Balkan Medical Journal
Nicole C Dabbs, Christopher D Black, John C Garner
Determining muscle contractile properties following exercise is critical in understanding neuromuscular function. Following high intensity training, individuals often experience exercise induced muscle damage (EIMD). The purpose of this investigation was to determine the effect of whole-body vibration (WBV) on muscle contractile properties following EIMD. Twenty-seven females volunteered for 7 sessions and were randomly assigned to a treatment or control group. Muscle contractile properties were assessed via voluntary torque (VT), peak twitch torque (TT), time to reach peak torque, half relaxation time of twitch torque, percent activation (%ACT), rate of rise (RR), rate of decline (RD), mean and peak electromyography during maximum voluntary isometric contraction...
October 2016: Journal of Electromyography and Kinesiology
T E Odinets, Yu A Briskin
UNLABELLED: A frequent consequence of the treatment of breast cancer is the postmastectomy syndrome that combines psycho-emotional and functional disorders in various body systems. AIM: The objective of the present study was to evaluate the influence of the program of differential physical rehabilitation on the functional state of the autonomic nervous system in the women with the postmastectomy syndrome at the stationary stage of the rehabilitative treatment. MATERIAL AND METHODS: The study included 50 presenting with the postmastectomy syndrome following radical mastectomy as described by J...
May 2016: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
Thomas P Burghardt, Katalin Ajtai, Xiaojing Sun, Naoko Takubo, Yihua Wang
Muscle myosins transduce ATP free energy into actin displacement to power contraction. In vivo, myosin side chains are modified post-translationally under native conditions, potentially impacting function. Single myosin detection provides the 'bottom-up' myosin characterization probing basic mechanisms without ambiguities inherent to ensemble observation. Macroscopic muscle physiological experimentation provides the definitive 'top-down' phenotype characterizations that are the concerns in translational medicine...
May 2016: Open Biology
Le Li, Henry Shin, Xiaoyan Li, Sheng Li, Ping Zhou
This study assessed changes in electrical impedance myography (EIM) at different levels of isometric muscle contraction as well as during exhaustive exercise at 60% maximum voluntary contraction (MVC) until task failure. The EIM was performed on the biceps brachii muscle of 19 healthy subjects. The results showed that there was a significant difference between the muscle resistance (R) measured during the isometric contraction and when the muscle was completely relaxed. Post hoc analysis shows that the resistance increased at higher contractions (both 60% MVC and MVC), however, there were no significant changes in muscle reactance (X) during the isometric contractions...
April 22, 2016: Sensors
María E Latorre, Adrian L Lifschitz, Peter P Purslow
The heat-solubility of intramuscular collagen is usually conducted in 1/4 Ringer's solution at pH7.4, despite this ionic strength and pH being inappropriate for post-rigor meat. The current work studied the percentage of soluble collagen and hydrothermal isometric tension characteristics of perimysial strips on bovine semitendinosus muscles in either 1/4 Ringer's solution, distilled water, PBS, or a solution of the same salt concentration as 1/4 Ringer's but at pH5.6. Values of % soluble collagen were lower at pH7...
August 2016: Meat Science
Spencer A Murphy, Reivian Berrios, P Andrew Nelson, Francesco Negro, Dario Farina, Brian Schmit, Allison Hyngstrom
The purpose of this study was to use high density surface EMG recordings to quantify stroke-related abnormalities in motor unit firing behavior during repeated sub-maximal knee extensor contractions. A high density surface EMG system (sEMG) was used to record and extract single motor unit firing behavior in the vastus lateralis muscle of 6 individuals with chronic stroke and 8 controls during repeated sub-maximal isometric knee extension contractions. Paretic motor unit firing rates were increased with subsequent contractions (6...
2015: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Suthichan Malai, Sopa Pichaiyongwongdee, Prasert Sakulsriprasert
OBJECTIVE: To determine the immediate effect of hold-relax (HR) stretching of the iliopsoas muscle on pain, transversus abdominis (TrA) activation capacity, lumbar stability level, lumbar lordosis angle and iliopsoas muscle length in chronic non-specific low back pain (CNSLBP) with lumbar hyperlordosis. MATERIAL AND METHOD: Participants aged from 30-55 years with CNSLBP with lumbar hyperlordosis were divided in two groups: (Group 1) Intervention group received 10-second isometric contraction ofthe iliopsoas muscle (HR), 10-second rest, 20-second static stretch, 5 repetitions...
June 2015: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
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