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https://www.readbyqxmd.com/read/28447141/the-iliotibial-band-and-anterolateral-capsule-have-a-combined-attachment-to-the-segond-fracture
#1
Marcio Albers, Humza Shaikh, Elmar Herbst, Kentaro Onishi, Kanto Nagai, Volker Musahl, Freddie H Fu
The purpose of this report was to describe the injury mechanism, surgical findings, and outcomes in a 21-year-old professional female football player who presented with a complete anterior cruciate ligament (ACL) rupture and Segond fracture. Interview and video analysis were performed to elicit the injury mechanism. Clinical examination and imaging revealed a complete ACL tear, Segond fracture, lateral meniscus tear, MCL sprain, and posterolateral corner sprain. Examination under anaesthesia revealed Grade 2 pivot shift and varus/valgus instability...
April 26, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28437755/an-in-vitro-study-of-cartilage-meniscus-tribology-to-understand-the-changes-caused-by-a-meniscus-implant
#2
Sara Ehsani Majd, Aditya Iman Rizqy, Hans J Kaper, Tannin A Schmidt, Roel Kuijer, Prashant K Sharma
Active lifestyles increase the risk of meniscal injury. A permanent meniscus implant of polycarbonate urethane (PCU) is a promising treatment to postpone/prevent total knee arthroplasty. Study of the changes in articular cartilage tribology in the presence of PCU is essential in developing the optimum meniscus implant. Therefore, a cartilage-meniscus reciprocating, sliding model was developed in vitro, mimicking the stance and swing phases of the gait cycle. The meniscus was further replaced with PCU and surface-modified PCUs (with C18 chains, mono-functional polydimethylsiloxane groups and mono-functional polytetrafluoroethylene groups) to study the changes...
April 18, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28434217/bilateral-hypoplasia-of-the-medial-and-lateral-menisci
#3
Yoon-Seok Youm, Sung-Do Cho, Hye-Yong Cho, Tae-Wook Kang
Hypoplasia of the meniscus is a very rare congenital abnormality, with only a few cases reported to date. A 9-year-old girl visited our hospital due to lateral knee pain following a hyperextension injury to the left knee. Magnetic resonance imaging showed hypoplasia of the medial and lateral menisci, as well as a posterior horn tear of the lateral meniscus, in both knee joints. To our knowledge, this is the first report of a patient with hypoplasia of the medial and lateral menisci in both knee joints.
April 25, 2017: Knee Surgery & related Research
https://www.readbyqxmd.com/read/28425824/isolated-acl-versus-multiple-knee-ligament-injury-associations-with-patient-characteristics-cartilage-status-and-meniscal-tears-identified-during-acl-reconstruction
#4
Ronald W B Wyatt, Maria C S Inacio, Kate D Bellevue, Alan L Schepps, Gregory B Maletis
OBJECTIVES: The objectives of this study were to determine (1) if patients undergoing reconstruction of an isolated anterior cruciate ligament (ACL) tear had different characteristics (age, gender, body mass index [BMI]) than patients undergoing ACL reconstruction (ACLR) with multiple knee ligament (MKL) tears and (2) whether there was a difference in prevalence of articular cartilage injury and meniscus tears between these two groups. METHODS: Patients undergoing primary ACLR between February 2005 and September 2013 were identified through an ACLR registry...
April 20, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28409107/a-transosseous-bone-bridge-repair-for-posterior-horn-meniscal-root-tears-during-anterior-cruciate-ligament-reconstruction
#5
Jonathan M Frank, Daniel J Liechti, Jack Anavian, Thomas R Hackett
Meniscal root tears occur in isolation or concurrently with ligamentous knee injury and cause significantly altered knee mechanics with the loss of normal meniscus hoop stress. This loss of normal meniscus function can result in abnormal knee kinematics and, subsequently, more rapid degenerative changes of the knee articular surface. In the setting of anterior cruciate ligament tear, the posterolateral meniscus root is most commonly damaged. Several techniques exist for meniscus root repair; however, none have been shown to be clearly superior...
February 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28407495/stem-cell-delivery-in-tissue-specific-hydrogel-enabled-meniscal-repair-in-an-orthotopic-rat-model
#6
Xiaoning Yuan, Yiyong Wei, Aránzazu Villasante, Johnathan J D Ng, Derya E Arkonac, Pen-Hsiu Grace Chao, Gordana Vunjak-Novakovic
Interest in non-invasive injectable therapies has rapidly risen due to their excellent safety profile and ease of use in clinical settings. Injectable hydrogels can be derived from the extracellular matrix (ECM) of specific tissues to provide a biomimetic environment for cell delivery and enable seamless regeneration of tissue defects. We investigated the in situ delivery of human mesenchymal stem cells (hMSCs) in decellularized meniscus ECM hydrogel to a meniscal defect in a nude rat model. First, decellularized meniscus ECM hydrogel retained tissue-specific proteoglycans and collagens, and significantly upregulated expression of fibrochondrogenic markers by hMSCs versus collagen hydrogel alone in vitro...
July 2017: Biomaterials
https://www.readbyqxmd.com/read/28406879/physical-examination-of-the-knee-meniscus-cartilage-and-patellofemoral-conditions
#7
Robert D Bronstein, Joseph C Schaffer
The knee is one of the most commonly injured joints in the body. Its superficial anatomy enables diagnosis of the injury through a thorough history and physical examination. Examination techniques for the knee described decades ago are still useful, as are more recently developed tests. Proper use of these techniques requires understanding of the anatomy and biomechanical principles of the knee as well as the pathophysiology of the injuries, including tears to the menisci and extensor mechanism, patellofemoral conditions, and osteochondritis dissecans...
May 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28400662/early-anterior-cruciate-ligament-reconstruction-can-save-meniscus-without-any-complications
#8
Chang-Ik Hur, Eun-Kyoo Song, Sung-Kyu Kim, Seung-Hun Lee, Jong-Keun Seon
BACKGROUND: Early ACL reconstruction, before retuning to activity eliminates recurrent episodes of instability and thereby decreases chances of meniscal and cartilage injury. However, there are no clear and uniform guidelines regarding the timing of ACL reconstruction or clarity in the definition of early and delayed reconstruction to reduce the complications after reconstruction in the ACL injured knee. The purpose of this study was to compare the clinical outcome, stability, muscle power, and postural control after early and delayed anterior cruciate ligament (ACL) reconstruction...
March 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28397004/the-frequency-of-cartilage-lesions-in-non-injured-knees-with-symptomatic-meniscus-tears-results-from-an-arthroscopic-and-nir-near-infrared-spectroscopic-investigation
#9
Gunter Spahn, Holger Plettenberg, Martin Hoffmann, Holm-Torsten Klemm, Christoph Brochhausen-Delius, Gunther O Hofmann
INTRODUCTION: Are symptomatic tear injuries to the menisci of the knee frequently or always associated with cartilage damage to the corresponding articular surfaces and other joint surfaces, respectively? METHODS: A total of 137 patients (medial n = 127; lateral n = 10) underwent a meniscus resection. These patients showed no signs of a clear radiographic arthrosis and no MRI-detectable cartilage lesions > grade II. Traumatic injury was ruled out with a thorough medical history...
April 10, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28383764/risk-factors-for-radiographic-joint-space-narrowing-and-patient-reported-outcomes-of-post-traumatic-osteoarthritis-after-acl-reconstruction-data-from-the-moon-cohort
#10
Morgan H Jones, Kurt P Spindler
The Multicenter Orthopaedic Outcomes Network (MOON) is an NIH-funded prospective, longitudinal cohort of over 3,500 patients who have undergone anterior cruciate ligament reconstruction (ACLR) by 14 sports medicine surgeons at 7 academic medical centers. Patient reported outcome questionnaires (PRO's) are completed at baseline and multiple timepoints after surgery, and a nested cohort of patients return for radiographs to assess the development of joint space changes. We review the risk factors for worse patient reported outcomes, the predictors of clinically significant symptoms of post-traumatic osteoarthritis (PTOA), and the factors associated with more radiographic joint space narrowing...
April 6, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28364144/current-advances-in-the-development-of-natural-meniscus-scaffolds-innovative-approaches-to-decellularization-and-recellularization
#11
REVIEW
Yunbin Chen, Jiaxin Chen, Zeng Zhang, Kangliang Lou, Qi Zhang, Shengyu Wang, Jinhu Ni, Wenyue Liu, Shunwu Fan, Xianfeng Lin
The increasing rate of injuries to the meniscus indicates the urgent need to develop effective repair strategies. Irreparably damaged menisci can be replaced and meniscus allografts represent the treatment of choice; however, they have several limitations, including availability and compatibility. Another approach is the use of artificial implants but their chondroprotective activities are still not proved clinically. In this situation, tissue engineering offers alternative natural decellularized extracellular matrix (ECM) scaffolds, which have shown biomechanical properties comparable to those of native menisci and are characterized by low immunogenicity and promising regenerative potential...
March 31, 2017: Cell and Tissue Research
https://www.readbyqxmd.com/read/28358780/the-cure-that-lies-within-the-mind-body-connection-in-orthopaedics
#12
Erin Sullivan, Jeremy Hudson
The mind and the body are clearly intertwined in ways that are only now being discovered. In the orthopaedic world, injuries and diseases are often classified and described in a very organized, discrete fashion-The radius is fractured, the ACL or meniscus or rotator cuff is torn, the ankle is sprained, and/or the lumbar spine has a disc herniation. Although it is, in many ways, almost comforting to think about injuries or orthopaedic issues in this manner, what about the many patients who fail to fall into this classification? What about the thousands of patients with severe unexplained chronic pain or patients who just are not improving with the typical treatment algorithm...
March 2017: Orthopaedic Nursing
https://www.readbyqxmd.com/read/28355098/meniscus-beyond-mechanics-using-biology-to-advance-our-understanding-of-meniscus-injury-and-treatment
#13
Muhammad Farooq Rai, Amy L McNulty
Meniscus tissues were historically considered vestigial structures in the knee, and largely remained an unexplored and underappreciated area of research. However, this concept was refuted with the discovery that loss of meniscus tissue leads to joint degeneration and development of osteoarthritis (OA). These findings have led to a growing interest in the role of the meniscus in knee stability and joint health and have brought the meniscus to the forefront of orthopaedic research. While the critical role of the meniscus in joint health has been established, little is known about the biomechanical, biochemical, and molecular signaling pathways that are involved in meniscus homeostasis and pathogenesis...
March 29, 2017: Connective Tissue Research
https://www.readbyqxmd.com/read/28345597/post-traumatic-osteoarthritis-in-mice-following-mechanical-injury-to-the-synovial-joint
#14
Muhammad Farooq Rai, Xin Duan, James D Quirk, Nilsson Holguin, Eric J Schmidt, Nobuaki Chinzei, Matthew J Silva, Linda J Sandell
We investigated the spectrum of lesions characteristic of post-traumatic osteoarthritis (PTOA) across the knee joint in response to mechanical injury. We hypothesized that alteration in knee joint stability in mice reproduces molecular and structural features of PTOA that would suggest potential therapeutic targets in humans. The right knees of eight-week old male mice from two recombinant inbred lines (LGXSM-6 and LGXSM-33) were subjected to axial tibial compression. Three separate loading magnitudes were applied: 6N, 9N, and 12N...
March 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28345407/knee-menisci
#15
James Kevin Bryceland, Andrew John Powell, Thomas Nunn
The menisci of the knees are semicircular fibrocartilaginous structures consisting of a hydrophilic extracellular matrix containing a network of collagen fibers, glycoproteins, and proteoglycans maintained by a cellular component. The menisci are responsible for more than 50% of load transmission across the knee and increase joint congruity thereby also aiding in fluid film lubrication of the joint. In the United Kingdom, meniscal tears are the most common form of intra-articular knee injury and one of the commonest indications for orthopedic intervention...
April 2017: Cartilage
https://www.readbyqxmd.com/read/28334504/redd1-deficiency-impairs-autophagy-and-mitochondrial-biogenesis-in-articular-cartilage-and-increases-the-severity-of-experimental-osteoarthritis
#16
Oscar Alvarez-Garcia, Tokio Matsuzaki, Merissa Olmer, Lars Plate, Jeffery W Kelly, Martin K Lotz
Objective REDD1 is an endogenous inhibitor of mTOR that regulates cellular stress responses. REDD1 expression is decreased in aged and osteoarthritis (OA) cartilage and it regulates mTOR signaling and autophagy in articular chondrocytes in vitro. The present study investigated the effects of REDD1 deletion in vivo using a mouse model of experimental OA. Methods Severity of OA was histologically assessed in 4-month-old wild-type and in Redd1(-/-) mice subjected to surgical destabilization of the medial meniscus (DMM)...
March 23, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/28318650/the-distribution-of-vascular-endothelial-growth-factor-in-human-meniscus-and-a-meniscal-injury-model
#17
Zhichao Lu, Takayuki Furumatsu, Masataka Fujii, Ami Maehara, Toshifumi Ozaki
BACKGROUND: The meniscus plays an important role in controlling the complex biomechanics of the knee. Meniscus injury is common in the knee joint. The perimeniscal capillary plexus supplies the outer meniscus, whereas the inner meniscus is composed of avascular tissue. Angiogenesis factors, such as vascular endothelial growth factor (VEGF), have important roles in promoting vascularization of various tissues. VEGF-mediated neovascularization is beneficial to the healing of injured tissues...
March 15, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28293698/anterolateral-ligament-abnormalities-are-associated-with-peripheral-ligament-and-osseous-injuries-in-acute-ruptures-of-the-anterior-cruciate-ligament
#18
Camilo Partezani Helito, Paulo Victor Partezani Helito, Renata Vidal Leão, Marco Kawamura Demange, Marcelo Bordalo-Rodrigues
PURPOSE: Few studies have used MRI to identify the ALL. As it was shown that it is not possible to precisely characterize this ligament in all examination, it is important to identify concomitant lesions that can help in diagnosing ALL abnormalities. It is important to characterise this injury due to its association with anterolateral knee instability. Thus, the present study was performed to determine the frequency of ALL injuries in patients with acute ACL rupture and to analyse its associated knee lesions...
March 14, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28289817/the-all-inside-meniscal-repair-technique-has-less-risk-of-injury-to-the-lateral-geniculate-artery-than-the-inside-out-repair-technique-when-suturing-the-lateral-meniscus
#19
Adrián Cuéllar, Ricardo Cuéllar, Jorge Díaz Heredia, Asier Cuéllar, Ignacio García-Alonso, Miguel Angel Ruiz-Ibán
PURPOSE: To evaluate the risk of injury to the inferior lateral geniculate artery with two different techniques for lateral meniscus repair. METHODS: Eight cadaveric knees were used. Inside-out sutures and an all-inside suture device were placed at the most lateral edge of the popliteal hiatus, and 15 and 30 mm anterior to this point. The minimum distances between the sutures and the inferior lateral geniculate artery were measured through a limited lateral arthrotomy...
March 13, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28282214/clinical-and-radiographic-outcomes-of-meniscus-surgery-and-future-targets-for-biologic-intervention-a-review-of-data-from-the-moon-group
#20
Robert W Westermann, Morgan Jones, David Wasserstein, Kurt P Spindler
Meniscus injury and treatment occurred with the majority of anterior cruciate ligament reconstructions (ACLR) in the multicenter orthopaedic outcomes (MOON) cohort. We describe the patient reported outcomes, radiographic outcomes and predictors of pain from meniscus injuries and treatment in the setting of ACLR. Patient reported outcomes improve significantly following meniscus repair with ACLR, but differences exist based on the meniscus injury laterally (medial or lateral). Patients undergoing medial meniscus repair have worse patient-reported outcomes and more pain compared to those with uninjured menisci...
March 10, 2017: Connective Tissue Research
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