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https://www.readbyqxmd.com/read/28515057/delaying-acl-reconstruction-and-treating-with-exercise-therapy-alone-may-alter-prognostic-factors-for-5-year-outcome-an-exploratory-analysis-of-the-kanon-trial
#1
Stephanie R Filbay, Ewa M Roos, Richard B Frobell, Frank Roemer, Jonas Ranstam, L Stefan Lohmander
AIM: Identify injury-related, patient-reported and treatment-related prognostic factors for 5-year outcomes in acutely ACL-ruptured individuals managed with early reconstruction plus exercise therapy, exercise therapy plus delayed reconstruction or exercise therapy alone. METHODS: Exploratory analysis of the Knee Anterior Cruciate Ligament, Nonsurgical versus Surgical Treatment (KANON) trial (ISRCTN84752559). Relationships between prognostic factors (baseline cartilage, meniscus and osteochondral damage, baseline extension deficit, baseline patient-reported outcomes, number of rehabilitation visits, graft/contralateral ACL rupture, non-ACL surgery and ACL treatment strategy) and 5-year Knee Injury and Osteoarthritis Outcome Score (KOOS) pain, symptoms, sport/recreation and quality of life (QOL) scores were explored using multivariable linear regression...
May 17, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28511649/il-10-ameliorates-tnf-%C3%AE-induced-meniscus-degeneration-in-mature-meniscal-tissue-in-vitro
#2
P Behrendt, K Häfelein, A Preusse-Prange, A Bayer, A Seekamp, B Kurz
BACKGROUND: Joint inflammation causes meniscus degeneration and can exacerbate post-traumatic meniscus injuries by extracellular matrix degradation, cellular de-differentiation and cell death. The aim of this study was to examine whether anti-inflammatory interleukin-10 exerts protective effects in an in vitro model of TNF-α-induced meniscus degeneration. METHODS: Meniscus tissue was harvested from the knees of adult cows. After 24 h of equilibrium explants were simultaneously treated with bovine TNF-α and IL-10...
May 16, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28507957/arthroscopic-synovectomy-in-bilateral-lipoma-arborescens
#3
Paolo Fornaciari, Pascal A Schai, Michael O Kurrer, G Ulrich Exner
INTRODUCTION: Lipoma arborescens (LA) is an uncommon condition that consists of a villous lipomatous proliferation of the synovial membrane. Open synovectomy has been previously selected as a curative treatment option. In recent years, some authors have published good results with arthroscopic interventions. We describe a well-documented case of bilateral LA of the knees treated with staged arthroscopic synovectomy. CASE REPORT: A 48-year-old North American woman without a history of trauma presented with recurrent effusions and mild pain in both knee joints for many years...
November 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28506133/clinical-outcomes-following-surgically-repaired-bucket-handle-meniscus-tears
#4
Michael J Moses, David E Wang, Maxwell Weinberg, Eric J Strauss
OBJECTIVES: Meniscus tears are one of the most common knee injuries. Our goal is to investigate the failure rate for surgically repaired bucket-handle meniscus tears and compare clinical outcomes of repairs that failed versus those that did not, at a minimum 2-year follow-up interval. METHODS: 51 patients were identified in this retrospective cohort study who experienced bucket-handle meniscus tears that were isolated or with concomitant ACL injury. Inclusion criteria included age range from 13-55 years, confirmed bucket-handle meniscus tear by MRI and intraoperatively, and at least two-years of post-operative follow-up following index repair...
May 16, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28499922/critical-analysis-of-the-lever-test-for-diagnosis-of-anterior-cruciate-ligament-insufficiency
#5
Patrick A Massey, Joshua D Harris, Leland A Winston, David M Lintner, Domenica A Delgado, Patrick C McCulloch
PURPOSE: To critically analyze the "lever test" in detecting anterior cruciate ligament (ACL) tears and to compare its accuracy with the Lachman, anterior drawer (AD), and pivot shift tests. METHODS: From June 2014 to June 2015, 91 subjects were analyzed. Inclusion criteria were subjects aged 16 to 60 years, presenting after a knee injury with subjective swelling, or an objective effusion and an uninjured normal contralateral knee for comparison. Exclusion criteria included previous knee ligamentous reconstruction, fracture of the distal femur or proximal tibia, bilateral knee injuries, or known cruciate ligament tear...
May 9, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28488835/incidence-of-injury-and-illness-in-south-african-professional-male-football-players-a-prospective-cohort-study
#6
Helen Bayne, Martin Schwellnus, Dina Janse Van Rensburg, Jhano Botha, Lervasen Pillay
BACKGROUND: Medical illnesses and sports-related injuries both have an effect on athlete health and performance. Epidemiology of injury and illness has been extensively researched during international football tournaments and the European football season. Reports on injury location and severity differ across geographical regions, and there is limited information on injury epidemiology in African football leagues. No studies have investigated the illness burden in football in Africa. METHODS: This was a prospective cohort study involving two football teams over the 10- month duration of the 2015/16 Premier Soccer League in South Africa...
May 9, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28469288/friction-properties-of-a-new-silk-fibroin-scaffold-for-meniscal-replacement
#7
Daniela Warnecke, N B Schild, S Klose, H Joos, R E Brenner, O Kessler, N Skaer, R Walker, M Freutel, A Ignatius, L Dürselen
The menisci protect the articular cartilage by reducing contact pressure in the knee. To restore their function after injury, a new silk fibroin replacement scaffold was developed. To elucidate its tribological properties, friction of the implant was tested against cartilage and glass, where the latter is typically used in tribological cartilage studies. The silk scaffold exhibited a friction coefficient against cartilage of 0.056, which is higher than meniscus against cartilage but in range of the requirements for meniscal replacements...
May 2017: Tribology International
https://www.readbyqxmd.com/read/28451597/outcomes-and-complications-after-all-epiphyseal-anterior-cruciate-ligament-reconstruction-in-skeletally-immature-patients
#8
Eric J Wall, Paul J Ghattas, Emily A Eismann, Gregory D Myer, Preston Carr
BACKGROUND: The safest and most effective technique for anterior cruciate ligament (ACL) reconstruction in skeletally immature patients is currently unknown. PURPOSE: To evaluate the functional and patient-reported outcomes of a specific all-epiphyseal ACL reconstruction technique in which the graft, bone tunnels, and fixation do not cross the knee growth plates. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: Twenty-seven patients (23 boys, 4 girls; mean age, 11 years; range, 8-15 years) underwent an all-epiphyseal ACL reconstruction with a single femoral transverse epiphyseal tunnel and primarily split tibial epiphyseal tunnels...
March 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28450773/mcmurray-s-test-and-joint-line-tenderness-for-medial-meniscus-tear-are-they-accurate
#9
Yogendra Gupta, Deepak Mahara, Arjun Lamichhane
BACKGROUND: Meniscus tears are the most common injury of the knee. The McMurray's test and Joint line tenderness for diagnosing meniscus tear have been widely tested, but results reported by different authors vary. The wide variations reported have an impact on clinical decision concerning whether to go for other diagnostic tests before going for diagnostic arthroscopy, which is considered as the gold standard.The purpose of this study was to determine the diagnostic value of Joint line tenderness and McMurray's test, as clinical signs, to diagnose underlying medial meniscus tears...
November 2016: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/28447141/the-iliotibial-band-and-anterolateral-capsule-have-a-combined-attachment-to-the-segond-fracture
#10
Marcio Albers, Humza Shaikh, Elmar Herbst, Kentaro Onishi, Kanto Nagai, Volker Musahl, Freddie H Fu
The purpose of this report was to describe the injury mechanism, surgical findings, and outcomes in a 21-year-old professional female football player who presented with a complete anterior cruciate ligament (ACL) rupture and Segond fracture. Interview and video analysis were performed to elicit the injury mechanism. Clinical examination and imaging revealed a complete ACL tear, Segond fracture, lateral meniscus tear, MCL sprain, and posterolateral corner sprain. Examination under anaesthesia revealed Grade 2 pivot shift and varus/valgus instability...
April 26, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28437755/an-in-vitro-study-of-cartilage-meniscus-tribology-to-understand-the-changes-caused-by-a-meniscus-implant
#11
Sara Ehsani Majd, Aditya Iman Rizqy, Hans J Kaper, Tannin A Schmidt, Roel Kuijer, Prashant K Sharma
Active lifestyles increase the risk of meniscal injury. A permanent meniscus implant of polycarbonate urethane (PCU) is a promising treatment to postpone/prevent total knee arthroplasty. Study of the changes in articular cartilage tribology in the presence of PCU is essential in developing the optimum meniscus implant. Therefore, a cartilage-meniscus reciprocating, sliding model was developed in vitro, mimicking the stance and swing phases of the gait cycle. The meniscus was further replaced with PCU and surface-modified PCUs (with C18 chains, mono-functional polydimethylsiloxane groups and mono-functional polytetrafluoroethylene groups) to study the changes...
April 18, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28434217/bilateral-hypoplasia-of-the-medial-and-lateral-menisci
#12
Yoon-Seok Youm, Sung-Do Cho, Hye-Yong Cho, Tae-Wook Kang
Hypoplasia of the meniscus is a very rare congenital abnormality, with only a few cases reported to date. A 9-year-old girl visited our hospital due to lateral knee pain following a hyperextension injury to the left knee. Magnetic resonance imaging showed hypoplasia of the medial and lateral menisci, as well as a posterior horn tear of the lateral meniscus, in both knee joints. To our knowledge, this is the first report of a patient with hypoplasia of the medial and lateral menisci in both knee joints.
April 25, 2017: Knee Surgery & related Research
https://www.readbyqxmd.com/read/28425824/isolated-acl-versus-multiple-knee-ligament-injury-associations-with-patient-characteristics-cartilage-status-and-meniscal-tears-identified-during-acl-reconstruction
#13
Ronald W B Wyatt, Maria C S Inacio, Kate D Bellevue, Alan L Schepps, Gregory B Maletis
OBJECTIVES: The objectives of this study were to determine (1) if patients undergoing reconstruction of an isolated anterior cruciate ligament (ACL) tear had different characteristics (age, gender, body mass index [BMI]) than patients undergoing ACL reconstruction (ACLR) with multiple knee ligament (MKL) tears and (2) whether there was a difference in prevalence of articular cartilage injury and meniscus tears between these two groups. METHODS: Patients undergoing primary ACLR between February 2005 and June 2013 were identified through an ACLR registry...
May 4, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28409107/a-transosseous-bone-bridge-repair-for-posterior-horn-meniscal-root-tears-during-anterior-cruciate-ligament-reconstruction
#14
Jonathan M Frank, Daniel J Liechti, Jack Anavian, Thomas R Hackett
Meniscal root tears occur in isolation or concurrently with ligamentous knee injury and cause significantly altered knee mechanics with the loss of normal meniscus hoop stress. This loss of normal meniscus function can result in abnormal knee kinematics and, subsequently, more rapid degenerative changes of the knee articular surface. In the setting of anterior cruciate ligament tear, the posterolateral meniscus root is most commonly damaged. Several techniques exist for meniscus root repair; however, none have been shown to be clearly superior...
February 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28407495/stem-cell-delivery-in-tissue-specific-hydrogel-enabled-meniscal-repair-in-an-orthotopic-rat-model
#15
Xiaoning Yuan, Yiyong Wei, Aránzazu Villasante, Johnathan J D Ng, Derya E Arkonac, Pen-Hsiu Grace Chao, Gordana Vunjak-Novakovic
Interest in non-invasive injectable therapies has rapidly risen due to their excellent safety profile and ease of use in clinical settings. Injectable hydrogels can be derived from the extracellular matrix (ECM) of specific tissues to provide a biomimetic environment for cell delivery and enable seamless regeneration of tissue defects. We investigated the in situ delivery of human mesenchymal stem cells (hMSCs) in decellularized meniscus ECM hydrogel to a meniscal defect in a nude rat model. First, decellularized meniscus ECM hydrogel retained tissue-specific proteoglycans and collagens, and significantly upregulated expression of fibrochondrogenic markers by hMSCs versus collagen hydrogel alone in vitro...
July 2017: Biomaterials
https://www.readbyqxmd.com/read/28406879/physical-examination-of-the-knee-meniscus-cartilage-and-patellofemoral-conditions
#16
Robert D Bronstein, Joseph C Schaffer
The knee is one of the most commonly injured joints in the body. Its superficial anatomy enables diagnosis of the injury through a thorough history and physical examination. Examination techniques for the knee described decades ago are still useful, as are more recently developed tests. Proper use of these techniques requires understanding of the anatomy and biomechanical principles of the knee as well as the pathophysiology of the injuries, including tears to the menisci and extensor mechanism, patellofemoral conditions, and osteochondritis dissecans...
May 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28400662/early-anterior-cruciate-ligament-reconstruction-can-save-meniscus-without-any-complications
#17
Chang-Ik Hur, Eun-Kyoo Song, Sung-Kyu Kim, Seung-Hun Lee, Jong-Keun Seon
BACKGROUND: Early ACL reconstruction, before retuning to activity eliminates recurrent episodes of instability and thereby decreases chances of meniscal and cartilage injury. However, there are no clear and uniform guidelines regarding the timing of ACL reconstruction or clarity in the definition of early and delayed reconstruction to reduce the complications after reconstruction in the ACL injured knee. The purpose of this study was to compare the clinical outcome, stability, muscle power, and postural control after early and delayed anterior cruciate ligament (ACL) reconstruction...
March 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28397004/the-frequency-of-cartilage-lesions-in-non-injured-knees-with-symptomatic-meniscus-tears-results-from-an-arthroscopic-and-nir-near-infrared-spectroscopic-investigation
#18
Gunter Spahn, Holger Plettenberg, Martin Hoffmann, Holm-Torsten Klemm, Christoph Brochhausen-Delius, Gunther O Hofmann
INTRODUCTION: Are symptomatic tear injuries to the menisci of the knee frequently or always associated with cartilage damage to the corresponding articular surfaces and other joint surfaces, respectively? METHODS: A total of 137 patients (medial n = 127; lateral n = 10) underwent a meniscus resection. These patients showed no signs of a clear radiographic arthrosis and no MRI-detectable cartilage lesions > grade II. Traumatic injury was ruled out with a thorough medical history...
April 10, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28383764/risk-factors-for-radiographic-joint-space-narrowing-and-patient-reported-outcomes-of-post-traumatic-osteoarthritis-after-acl-reconstruction-data-from-the-moon-cohort
#19
Morgan H Jones, Kurt P Spindler
The Multicenter Orthopaedic Outcomes Network (MOON) is an NIH-funded prospective, longitudinal cohort of over 3,500 patients who have undergone anterior cruciate ligament reconstruction (ACLR) by 14 sports medicine surgeons at 7 academic medical centers. Patient reported outcome questionnaires (PRO's) are completed at baseline and multiple timepoints after surgery, and a nested cohort of patients return for radiographs to assess the development of joint space changes. We review the risk factors for worse patient reported outcomes, the predictors of clinically significant symptoms of post-traumatic osteoarthritis (PTOA), and the factors associated with more radiographic joint space narrowing...
April 6, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28364144/current-advances-in-the-development-of-natural-meniscus-scaffolds-innovative-approaches-to-decellularization-and-recellularization
#20
REVIEW
Yunbin Chen, Jiaxin Chen, Zeng Zhang, Kangliang Lou, Qi Zhang, Shengyu Wang, Jinhu Ni, Wenyue Liu, Shunwu Fan, Xianfeng Lin
The increasing rate of injuries to the meniscus indicates the urgent need to develop effective repair strategies. Irreparably damaged menisci can be replaced and meniscus allografts represent the treatment of choice; however, they have several limitations, including availability and compatibility. Another approach is the use of artificial implants but their chondroprotective activities are still not proved clinically. In this situation, tissue engineering offers alternative natural decellularized extracellular matrix (ECM) scaffolds, which have shown biomechanical properties comparable to those of native menisci and are characterized by low immunogenicity and promising regenerative potential...
March 31, 2017: Cell and Tissue Research
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