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https://www.readbyqxmd.com/read/28102713/factors-associated-with-the-status-of-meniscal-tears-following-meniscal-repair-concomitant-with-anterior-cruciate-ligament-reconstruction
#1
Takehiko Matsushita, Kanto Nagai, Daisuke Araki, Toshikazu Tanaka, Tomoyuki Matsumoto, Kotaro Nishida, Masahiro Kurosaka, Ryosuke Kuroda
Purpose Anterior cruciate ligament (ACL) injuries are often accompanied by meniscal tears. Meniscal repair is typically performed during ACL reconstruction. However, retear of the meniscus after repair is frequent. The purpose of this study was to analyze the factors associated with meniscal healing after meniscal repair concomitant with ACL reconstruction. Materials and Methods Eighty-seven meniscal repairs in 87 patients who received meniscal repair combined with ACL reconstruction and received second-look arthroscopy at a mean of postoperatively 15...
January 19, 2017: Connective Tissue Research
https://www.readbyqxmd.com/read/28097689/investigating-magnetic-susceptibility-of-human-knee-joint-at-7-tesla
#2
Hongjiang Wei, Russell Dibb, Kyle Decker, Nian Wang, Yuyao Zhang, Xiaopeng Zong, Weili Lin, Daniel B Nissman, Chunlei Liu
PURPOSE: To evaluate the magnetic susceptibility properties of different anatomical structures within the knee joint using quantitative susceptibility mapping (QSM). METHODS: A collagen tissue model was simulated and ex vivo animal cartilage experiments were conducted at 9.4 Tesla (T) to evaluate the B0 orientation-dependent magnetic susceptibility contrast observed in cartilage. Furthermore, nine volunteers (six healthy subjects without knee pain history and three patients with known knee injury, between 29 and 58 years old) were scanned using gradient-echo acquisitions on a high-field 7T MR scanner...
January 17, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28095754/3d-co-culture-of-meniscal-cells-and-mesenchymal-stem-cells-in-collagen-type-i-hydrogel-on-a-small-intestinal-matrix-a-pilot-study-towards-equine-meniscus-tissue-engineering
#3
Antje Kremer, Iris Ribitsch, Jenny Reboredo, Julia Dürr, Monika Egerbacher, Florien Jenner, Heike Walles
Meniscal injuries are the most frequently encountered soft tissue injuries in the equine stifle joint. Due to the inherent limited repair potential of meniscal tissue, meniscal injuries do not only affect the meniscus itself but also lead to impaired joint homeostasis and secondary osteoarthritis. The presented study compares 3D co-culture constructs of primary equine mesenchymal stem cells (MSC) and meniscus cells (MC) seeded on three different scaffolds - a cell-laden collagen type I hydrogel (Col I gel), a tissue-derived small intestinal matrix scaffold (SIS-muc) and a combination thereof - for their qualification to be applied for meniscus tissue engineering...
January 18, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28093371/sonographically-guided-knee-meniscus-injections-feasibility-techniques-and-validation
#4
Michael R Baria, Jacob L Sellon, Dan Lueders, Jay Smith
BACKGROUND: There is a growing interest in the use of biologic agents such as platelet-rich plasma and mesenchymal stem/stromal cells to treat musculoskeletal injuries, including meniscal tears. Although prior research has documented the role of diagnostic ultrasound to evaluate meniscal tears, sonographically guided (SG) techniques to specifically deliver therapeutic agents into the meniscus have not been described. OBJECTIVE: To describe and validate SG injection techniques for the body and posterior horn of the medial and lateral meniscus...
January 13, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28090449/ultrashort-time-to-echo-magnetic-resonance-techniques-for-the-musculoskeletal-system
#5
REVIEW
Palanan Siriwanarangsun, Sheronda Statum, Reni Biswas, Won C Bae, Christine B Chung
Magnetic resonance (MR) imaging has been widely implemented as a non-invasive modality to investigate musculoskeletal (MSK) tissue disease, injury, and pathology. Advancements in MR sequences provide not only enhanced morphologic contrast for soft tissues, but also quantitative biochemical evaluation. Ultrashort time to echo (UTE) sequence, in particular, enables novel morphologic and quantitative evaluation of previously unseen MSK tissues. By using short minimum echo times (TE) below 1 msec, the UTE sequence can unveil short T2 properties of tissues including the deepest layers of the articular cartilage, cartilaginous endplate at the discovertebral junction, the meniscus, and the cortical bone...
December 2016: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28090444/bone-marrow-edema-like-lesions-bmels-are-associated-with-higher-t1%C3%AF-and-t2-values-of-cartilage-in-anterior-cruciate-ligament-acl-reconstructed-knees-a-longitudinal-study
#6
Jingshan Gong, Valentina Pedoia, Luca Facchetti, Thomas M Link, C Benjamin Ma, Xiaojuan Li
BACKGROUND: To evaluate the longitudinal changes of bone marrow edema-like lesions (BMELs) in patients after anterior cruciate ligament (ACL) reconstruction and to investigate the effect of BMELs on cartilage matrix composition changes measured using MR T1ρ and T2 mapping. METHODS: Patients with acute ACL tear were enrolled in a prospective study. MR imaging was performed at baseline (before surgeries) and at 6-month, 1-year and 2-year after ACL reconstruction...
December 2016: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28089224/loading-of-the-medial-meniscus-in-the-acl-deficient-knee-a-multibody-computational-study
#7
Trent M Guess, Swithin Razu
The menisci of the knee reduce tibiofemoral contact pressures and aid in knee lubrication and nourishment. Meniscal injury occurs in half of knees sustaining anterior cruciate ligament injury and the vast majority of tears in the medial meniscus transpire in the posterior horn region. In this study, computational multibody models of the knee were derived from medical images and passive leg motion for two female subjects. The models were validated against experimental measures available in the literature and then used to evaluate medial meniscus contact force and internal hoop tension...
January 11, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28060534/is-it-necessary-to-repair-stable-ramp-lesions-of-the-medial-meniscus-during-anterior-cruciate-ligament-reconstruction
#8
Xin Liu, Hui Zhang, Hua Feng, Lei Hong, Xue-Song Wang, Guan-Yang Song
BACKGROUND: A special type of meniscal lesion involving the peripheral attachment of the posterior horn of the medial meniscus (PHMM), termed a "ramp lesion," is commonly associated with an anterior cruciate ligament (ACL) injury. However, its treatment is still controversial. Recently, stable ramp lesions treated with abrasion and trephination alone have been shown to have good clinical outcomes after ACL reconstruction. HYPOTHESIS: Stable ramp lesions treated with abrasion and trephination alone during ACL reconstruction will result in similar clinical outcomes compared with those treated with surgical repair...
December 1, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28057910/arthroscopic-detection-of-medial-meniscal-injury-in-small-breed-dogs-with-the-use-of-a-joint-distractor
#9
Joo-Ho Kim, Su-Young Heo, Hae-Beom Lee
The goal of the present study was to evaluate the diagnostic value of a joint distractor in arthroscopy in small-breed dogs. Sixty stifle joints, which were collected from thirty cadavers, were used in this study. To simulate different injuries, no medial meniscal tear, a full-thickness vertical longitudinal tear, a partial-thickness vertical longitudinal tear, full- and partial-thickness vertical longitudinal tears, or a peripheral detachment were made on the caudal horn of the medial meniscus of each stifle joint along with cranial cruciate ligament (CrCL) rupture...
January 4, 2017: Journal of Veterinary Science
https://www.readbyqxmd.com/read/28056527/osteochondral-allograft-transplantation-of-the-knee
#10
Rachel M Frank, Simon Lee, David Levy, Sarah Poland, Maggie Smith, Nina Scalise, Gregory L Cvetanovich, Brian J Cole
BACKGROUND: Osteochondral allograft transplantation (OAT) is being performed with increasing frequency, and the need for reoperations is not uncommon. PURPOSE: To quantify survival for OAT and report findings at reoperations. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: A review of prospectively collected data of 224 consecutive patients who underwent OAT by a single surgeon with a minimum follow-up of 2 years was conducted...
December 1, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28038475/readability-of-online-sources-regarding-meniscal-tears
#11
Jonathan D Hodax, Grayson L Baird, Trevor McBride, Brett D Owens
Meniscal injuries are extremely common, with an incidence of 8.3 per 1,000 person/years in young, active individuals. Patients often turn to the internet to glean information about their injuries, and even to guide decision making about treatment. Much research has been done demonstrating that a reading level of eighth grade or lower is appropriate for accurately communicating written information to patients, yet medical practitioners often fail to meet this requirement. To better examine the information patients receive about meniscal injuries, we set out to evaluate the reading level and content of three commonly used search terms on the three search engines with the largest market share...
December 30, 2016: Journal of Knee Surgery
https://www.readbyqxmd.com/read/28028568/arthroscopic-all-inside-ramp-lesion-repair-using-the-posterolateral-transseptal-portal-view
#12
Sohrab Keyhani, Jin Hwan Ahn, René Verdonk, Mehran Soleymanha, Mohammadreza Abbasian
PURPOSE: The purpose of this study was to evaluate and describe the clinical results and outcomes of a novel method for all-inside suture repair of medial meniscus ramp lesions through posteromedial and posterolateral transseptal portals during anterior cruciate ligament (ACL) reconstruction. Further, this investigation compared the posterolateral view to the notch view for diagnosis and repair. METHODS: Between 2011 and 2014, 166 patients had ramp lesions concomitantly with ACL injury; 128 patients (107 men and 21 women) were enrolled in the study after qualification...
December 27, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28026970/engineering-3d-bioplotted-scaffolds-to-induce-aligned-extracellular-matrix-deposition-for-musculoskeletal-soft-tissue-replacement
#13
Paul B Warren, Pedro Huebner, Jeffrey T Spang, Rohan A Shirwaiker, Matthew B Fisher
PURPOSE: Tissue engineering and regenerative medicine approaches have the potential to overcome the challenges associated with current treatment strategies for meniscus injuries. 3D-Bioplotted scaffolds are promising, but have not demonstrated the ability to guide the formation of aligned collagenous matrix in vivo, which is critical for generating functional meniscus tissue. In this study, we evaluate the ability of 3D-Bioplotted scaffold designs with varying interstrand spacing to induce the deposition of aligned matrix in vivo...
December 27, 2016: Connective Tissue Research
https://www.readbyqxmd.com/read/28018086/leukocyte-poor-platelet-rich-plasma-to-treat-degenerative-meniscal-tear-a-case-report
#14
J P Betancourt, W D Murrell
A traumatic and/or degenerative meniscus lesion is thought to be a clinical manifestation of early-onset osteoarthritis (OA), which is a chronic progressive condition that can cause substantial pain and disability. Platelet-rich plasma (PRP) is an emerging treatment option that has been reported to improve healing. Here, we present a case of a 29-year-old woman, with left anterior and medial knee pain, without history of trauma or injury. The patient was managed with leukocyte-poor PRP injections derived from her peripheral blood with high concentrations of platelets, platelet-derived growth factors, and bioactive proteins, with a total follow-up of 30 months...
October 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28005443/identification-and-characterization-of-adult-mouse-meniscus-stem-progenitor-cells
#15
Laura W Gamer, Rui Rui Shi, Ashira Gendelman, Dylan Mathewson, Jackson Gamer, Vicki Rosen
Meniscal damage is a common problem that accelerates the onset of knee osteoarthritis. Stem cell based tissue engineering treatment approaches have shown promise in preserving meniscal tissue and restoring meniscal function. The purpose of our study was to identify meniscus-derived stem/progenitor cells (MSPCs) from mouse, a model system that allows for in vivo analysis of the mechanisms underlying meniscal injury and healing. MSPCs were isolated from murine menisci grown in explant culture and characterized for stem cell properties...
December 22, 2016: Connective Tissue Research
https://www.readbyqxmd.com/read/28005104/potential-operating-room-fire-hazard-of-bone-cement
#16
Udai S Sibia, Kevin Connors, Sarah Dyckman, Hamid R Zahiri, Ivan George, Adrian E Park, James H MacDonald
Approximately 600 cases of operating room (OR) fires are reported annually. Despite extensive fire safety education and training, complete elimination of OR fires still has not been achieved. Each fire requires an ignition source, a fuel source, and an oxidizer. In this case report, we describe the potential fire hazard of bone cement in the OR. A total knee arthroplasty was performed with a standard medial parapatellar arthrotomy. Tourniquet control was used. After bone cement was applied to the prepared tibial surface, the surgeon used an electrocautery device to resect residual lateral meniscus tissue-and started a fire in the operative field...
November 2016: American Journal of Orthopedics
https://www.readbyqxmd.com/read/28002905/arthroscopic-all-inside-treatment-of-popliteomeniscal-fascicles-tears-surgical-technique-and-results-from-the-first-6-consecutive-patients
#17
R Simonetta, G Di Vico, R Papalia, S Vasta, V Denaro
Athletes whose knees are subjected to sudden changes of direction and high jumps such as martial arts athletes, dancers, wrestlers and football players are at higher risk of injuring popliteomeniscal fascicles. Painful squatting and mechanical symptoms such as locking sensation are common. Current available treatments includes open or arthroscopic in repair. Arthroscopic repair with all-inside device can relieve symptoms and restore knee function. Six patients from two surgical centers with isolated popliteomeniscal fascicles tears were treated with arthroscopic all-inside repair...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/27984833/-injuries-during-equestrian-vaulting
#18
M Endruweit, J Dargel, J Siewe, I Becker, R Sobottke
Background: Vaulting is the least studied equestrian sports regarding the occurrence of injuries. As its sequences of motion do not compare to riding, vaulting must be assessed separately. Material and Methods: This retrospective, questionnaire-aided survey was aimed to gain insight into the overall frequency of injuries among equestrian vaulters. The second part of the study looked into the knee injuries that occurred. Survey forms were sent to 60 vaulting and equestrian clubs all over Germany, making for a response rate of 63 %...
December 2016: Sportverletzung Sportschaden: Organ der Gesellschaft Für Orthopädisch-Traumatologische Sportmedizin
https://www.readbyqxmd.com/read/27965260/ccl2-ccr2-but-not-ccl5-ccr5-mediates-monocyte-recruitment-inflammation-and-cartilage-destruction-in-osteoarthritis
#19
Harini Raghu, Christin M Lepus, Qian Wang, Heidi H Wong, Nithya Lingampalli, Francesca Oliviero, Leonardo Punzi, Nicholas J Giori, Stuart B Goodman, Constance R Chu, Jeremy B Sokolove, William H Robinson
OBJECTIVES: While various monocyte chemokine systems are increased in expression in osteoarthritis (OA), the hierarchy of chemokines and chemokine receptors in mediating monocyte/macrophage recruitment to the OA joint remains poorly defined. Here, we investigated the relative contributions of the CCL2/CCR2 versus CCL5/CCR5 chemokine axes in OA pathogenesis. METHODS: Ccl2-, Ccr2-, Ccl5- and Ccr5-deficient and control mice were subjected to destabilisation of medial meniscus surgery to induce OA...
December 13, 2016: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/27956221/ethylene-glycol-and-glycerol-loading-and-unloading-in-porcine-meniscal-tissue
#20
Talal A Takroni, Hana Yu, Leila Laouar, Adetola B Adesida, Janet A W Elliott, Nadr M Jomha
The development of a long-term storage method for meniscus, a complex tissue of the knee prone to injury, would improve the procedure and outcomes of meniscus transplantation. Cryopreservation uses cryoprotective agents (CPAs) including ethylene glycol (EG) and glycerol to preserve a variety of live tissues, and understanding of the CPA permeation kinetics will be critical in designing a vitrification protocol for meniscus. The purpose of this preliminary study was to understand the loading and unloading behaviours of EG and glycerol in meniscus by observing their efflux...
December 9, 2016: Cryobiology
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