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https://www.readbyqxmd.com/read/28301219/management-of-comorbid-bipolar-disorder-and-substance-use-disorders
#1
Ihsan M Salloum, Edson Sherwood Brown
BACKGROUND: The comorbidity of substance use disorders (SUDs) in bipolar disorder is among the highest in psychiatric disorders. Evidence-based controlled psychosocial or pharmacological interventions trials, which may guide treatment decisions, have not been systematically reviewed. OBJECTIVE: To present a narrative review of the public health and clinical significance of this condition, including diagnostic and treatment implications, and to evaluate controlled trials conducted to date...
March 16, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28297025/association-of-stimulant-use-with-dopaminergic-alterations-in-users-of-cocaine-amphetamine-or-methamphetamine-a-systematic-review-and-meta-analysis
#2
Abhishekh H Ashok, Yuya Mizuno, Nora D Volkow, Oliver D Howes
Importance: Stimulant use disorder is common, affecting between 0.3% and 1.1% of the population, and costs more than $85 billion per year globally. There are no licensed treatments to date. Several lines of evidence implicate the dopamine system in the pathogenesis of substance use disorder. Therefore, understanding the nature of dopamine dysfunction seen in stimulant users has the potential to aid the development of new therapeutics. Objective: To comprehensively review the in vivo imaging evidence for dopaminergic alterations in stimulant (cocaine, amphetamine, or methamphetamine) abuse or dependence...
March 15, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28292456/prevention-of-and-interventions-for-dating-and-sexual-violence-in-adolescence
#3
REVIEW
Elizabeth Miller
Dating violence (also known as adolescent relationship abuse) and sexual violence are prevalent from the middle school years throughout adolescence, peak in young adulthood, and are associated with multiple poor physical and mental health consequences. By offering universal education and brief anticipatory guidance with all adolescent patients about healthy and unhealthy relationships and sexual consent, health care providers can help promote healthy adolescent sexual relationships, ensure youth know about available resources and supports for relationship abuse and sexual violence (including how to help a friend), and facilitate connections to victim service advocates, both for prevention and intervention...
April 2017: Pediatric Clinics of North America
https://www.readbyqxmd.com/read/28288554/the-associations-between-substance-use-sexual-behaviors-bullying-deviant-behaviors-health-and-cyber-dating-abuse-perpetration
#4
Joris Van Ouytsel, Elizabeth Torres, Hye Jeong Choi, Koen Ponnet, Michel Walrave, Jeff R Temple
Dating violence is an important public health concern and is considered to be a form of school violence. While digital technologies have enabled perpetrators of dating violence to target their victims online (cyber dating abuse), little is known about how this form of perpetration relates to specific adolescent risk behaviors. This brief research report focuses on the associations between substance use, sexual behaviors, deviant behaviors, self-reported health, and cyber dating abuse perpetration. Participants included 705 ethnically diverse adolescents ( n = 408; 57...
April 2017: Journal of School Nursing: the Official Publication of the National Association of School Nurses
https://www.readbyqxmd.com/read/28285304/men-s-views-on-depression-a-systematic-review-and-metasynthesis-of-qualitative-research
#5
Silvia Krumm, Carmen Checchia, Markus Koesters, Reinhold Kilian, Thomas Becker
BACKGROUND: According to the concept of "male depression," depression among men might be underdiagnosed and undertreated because of gender differences in symptoms and coping. There is evidence that men experience atypical depressive symptoms including irritability, aggression, substance abuse, and increased risk behavior. To date, a substantial number of qualitative studies on men's views on depression has been conducted in the last few decades. METHODS: Based on a systematic review and metasynthesis of qualitative studies on men's subjective perspectives on depression, we aim at a comprehensive understanding of men's subjective views on depression with a specific focus on masculinity constructions...
March 11, 2017: Psychopathology
https://www.readbyqxmd.com/read/28253948/-long-term-outcomes-of-the-treatment-of-pediatric-femoral-shaft-fractures-treated-with-bryant-s-vertical-traction
#6
J Urban, P Toufar, M Kloub
PURPOSE OF THE STUDY The paper aimed to evaluate the long-term outcomes of the treatment of diaphyseal femur fractures in children treated with Bryant's vertical traction. Moreover, we also assessed the size of overgrowth in the injured femur. MATERIAL AND METHODS The study included 23 patients with 23 femoral shaft fractures treated with Bryant's vertical traction at our department in 2009-2014. The following parameters were assessed: sex, ïnjured side, weight, age, mechanism of injury, potential abuse, type of fracture, duration of traction, and total length of hospital stay...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28248631/working-together-to-connect-care-a-metropolitan-tertiary-emergency-department-and-community-care-program
#7
Debra Harcourt, Clancy McDonald, Leonie Cartlidge-Gann, John Burke
Objective Frequent attendance by people to an emergency department (ED) is a global concern. A collaborative partnership between an ED and the primary and community healthcare sectors has the potential to improve care for the person who frequently attends the ED. The aims of the Working Together to Connect Care program are to decrease the number of presentations by providing focused community support and to integrate all healthcare services with the goal of achieving positive, patient-centred and directed outcomes...
March 2, 2017: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/28239898/early-signal-of-diverted-use-of-tropicamide-eye-drops-in-france
#8
Camille Ponté, Christian Pi, Aurore Palmaro, Emilie Jouanjus, Maryse Lapeyre-Mestre
BACKGROUND: Tropicamide is a mydriatic drug used as eye-drops for diagnostic or therapeutic purposes. From 2013, a diverted use by intravenous route has been suspected in Eastern Europe in opioids users. To recent date, no signal of a misuse has been identified in France. PURPOSE: To investigate an early signal of a diverted use of tropicamide eye drops and to collect information regarding motives of misusing and tropicamide-induced effects. METHODS: Information was obtained at 1/ regional level (Midi-Pyrénées area): reimbursement data and pharmacists' reports on suspicious requests, 2/ national level: reimbursement data and prescriptions suggesting possible abuse from the OSIAP (Ordonnances Suspectes, Indicateur d'Abus Possible) survey and 3/ international level: VigiBase® reports and Web sources...
February 27, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28238208/ask-me-self-reported-features-of-adolescents-experiencing-neglect-or-emotional-maltreatment-a-rapid-systematic-review
#9
REVIEW
A M Naughton, L E Cowley, V Tempest, S A Maguire, M K Mann, A M Kemp
BACKGROUND: Neglect is often overlooked in adolescence, due in part to assumptions about autonomy and misinterpretation of behaviors being part of normal adolescent development. Emotional maltreatment (abuse or neglect) has a damaging effect throughout the lifespan, but is rarely recognized amongst adolescents. Our review aims to identify features that adolescents experiencing neglect and/ or emotional maltreatment report. METHOD: A rapid review methodology searched 8 databases (1990-2014), supplemented by hand searching journals, and references, identifying 2,568 abstracts...
February 26, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28237191/child-sexual-abuse-and-exploitation-a-global-glimpse
#10
Howard Dubowitz
The view of what constitutes child abuse and neglect is dependent on the laws, cultural context, local thresholds and the availability. Since 1982, the International Society for the Prevention of Child Abuse and Neglect (ISPCAN) has conducted surveillance of child maltreatment and child protection every two years, published in World Perspectives on Child Abuse. It is hoped that up to date information will inform the development of laws, policies and programs to better address child abuse and neglect. This article is based on data on child sexual abuse and exploitation from 73 countries gathered online in 2015-16 for the 12 edition of World Perspectives...
February 22, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28216980/long-term-prognosis-in-patients-continuing-taking-antithrombotics-after-peptic-ulcer-bleeding
#11
Xi-Xu Wang, Bo Dong, Biao Hong, Yi-Qun Gong, Wei Wang, Jue Wang, Zhen-Yu Zhou, Wei-Jun Jiang
AIM: To investigate the long-term prognosis in peptic ulcer patients continuing taking antithrombotics after ulcer bleeding, and to determine the risk factors that influence the prognosis. METHODS: All clinical data of peptic ulcer patients treated from January 1, 2009 to January 1, 2014 were retrospectively collected and analyzed. Patients were divided into either a continuing group to continue taking antithrombotic drugs after ulcer bleeding or a discontinuing group to discontinue antithrombotic drugs...
January 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28216378/gender-differences-in-adverse-childhood-experiences-collective-violence-and-the-risk-for-addictive-behaviors-among-university-students-in-tunisia
#12
Sana El Mhamdi, Andrine Lemieux, Ines Bouanene, Arwa Ben Salah, Motohiro Nakajima, Kamel Ben Salem, Mustafa al'Absi
Adverse childhood experiences (ACE) have been linked to a variety of addictive behaviors. The recent adaptation of the ACE measure by the World Health Organization (WHO) allows for the assessment of the negative role of additional adverse experiences, such as extra-familial violence. To date, the relationship between extra-familial violence and addictive behaviors has not been assessed. We report the contribution of ACEs, including the new scales for extra-familial violence, on the risk for mental health problems and addictive behaviors by gender in a sample of young adults in Tunisia...
February 16, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28194935/a-potential-pet-radiotracer-for-the-5-ht2c-receptor-synthesis-and-in-vivo-evaluation-of-4-3-18-f-fluorophenethoxy-pyrimidine
#13
Juhyeon Kim, Byung Seok Moon, Byung Chul Lee, Ho-Young Lee, Hak Joong Kim, Hyunah Choo, Ae Nim Pae, Yong Seo Cho, Sun-Joon Min
The serotonin 2C receptor subtype (5-HT2C) is an excitatory 5-HT receptor widely distributed throughout the central nerve system. As the 5-HT2C receptor displays multiple actions on various neurotransmitter systems including glutamate, dopamine, epinephrine and -aminobutyric acid (GABA), abnormalities of the 5-HT2C receptor are associated with psychiatric diseases such as depression, schizophrenia, drug abuse, and anxiety. Up to date, three kinds of 5-HT2C PET radiotracers such as [11C]N-methylated arylazepine (1), [11C]WAY-163909 (2), [18F]fluorophenylcyclopropane (3) have been developed, but they may not be suitable for in vivo 5-HT2C imaging study due to their modest specific binding...
February 14, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/28165152/memory-errors-in-alibi-generation-how-an-alibi-can-turn-against-us
#14
William E Crozier, Deryn Strange, Elizabeth F Loftus
Alibis play a critical role in the criminal justice system. Yet research on the process of alibi generation and evaluation is still nascent. Indeed, similar to other widely investigated psychological phenomena in the legal system - such as false confessions, historical claims of abuse, and eyewitness memory - the basic assumptions underlying alibi generation and evaluation require closer empirical scrutiny. To date, the majority of alibi research investigates the social psychological aspects of the process...
February 6, 2017: Behavioral Sciences & the Law
https://www.readbyqxmd.com/read/28161446/drunk-bugs-chronic-vapour-alcohol-exposure-induces-marked-changes-in-the-gut-microbiome-in-mice
#15
Veronica L Peterson, Nicholas J Jury, Raúl Cabrera-Rubio, Lorraine A Draper, Fiona Crispie, Paul D Cotter, Timothy G Dinan, Andrew Holmes, John F Cryan
The gut microbiota includes a community of bacteria that play an integral part in host health and biological processes. Pronounced and repeated findings have linked gut microbiome to stress, anxiety, and depression. Currently, however, there remains only a limited set of studies focusing on microbiota change in substance abuse, including alcohol use disorder. To date, no studies have investigated the impact of vapour alcohol administration on the gut microbiome. For research on gut microbiota and addiction to proceed, an understanding of how route of drug administration affects gut microbiota must first be established...
April 14, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28156433/psychosocial-distress-screening-in-the-health-care-safety-net
#16
Theora Cimino, Anne Kinderman, Leslie Safier, Heather A Harris
91 Background: Recognizing that psychosocial distress (PSD) is underestimated in patients with cancer, the Commission on Cancer mandated screening using a validated tool. Studies of PSD screening exist, but none to date in a diverse, multicultural safety net setting where patients face challenges such as homelessness, mental illness, and substance abuse, which may augment PSD. METHODS: We performed a retrospective cohort study of patients with cancer offered PSD screening during 2015...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28139252/childhood-sexual-abuse-sexual-motives-and-adolescent-sexual-risk-taking-among-males-and-females-receiving-child-welfare-services
#17
Christine Wekerle, Abby L Goldstein, Masako Tanaka, Lil Tonmyr
Childhood sexual abuse (CSA) is associated with multiple negative outcomes, including increased risky sexual behavior. To date, the majority of research on the relationship between CSA and risky sex in adolescence has been limited, with a lack of focus on males and youth receiving child welfare services. Participants in the current study were 297 youth (mean age=15.98; SD=1.01, 57.6% female) from the child welfare system who reported being sexually active at the time of the survey. CSA was associated with severity of other types of maltreatment for both genders, and exposure to intimate partner violence for females only...
January 27, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28138269/utilization-of-dating-apps-by-men-who-have-sex-with-men-for-persuading-other-men-toward-substance-use
#18
Smith Boonchutima, Watsayut Kongchan
BACKGROUND: Dating apps play a major role in connecting men who are interested in meeting other men for sex. Besides finding a partner, these tools are also exploited for other activities such as encouraging people to get involved in the habit of illicit drug consumption (substance use). METHODS: This study evaluated the overall usage of dating apps among Thai men who have sex with men (MSMs), with an emphasis on abusing these apps to convey messages encouraging substance use...
2017: Psychology Research and Behavior Management
https://www.readbyqxmd.com/read/28130957/immunoassay-screening-in-urine-for-synthetic-cannabinoids-an-evaluation-of-the-diagnostic-efficiency
#19
Florian Franz, Verena Angerer, Hanna Jechle, Melanie Pegoro, Harald Ertl, Georg Weinfurtner, David Janele, Christian Schlögl, Matthias Friedl, Stefan Gerl, Reinhard Mielke, Ralf Zehnle, Matthias Wagner, Bjoern Moosmann, Volker Auwärter
BACKGROUND: The abuse of synthetic cannabinoids (SCs) as presumed legal alternative to cannabis poses a great risk to public health. For economic reasons many laboratories use immunoassays (IAs) to screen for these substances in urine. However, the structural diversity and high potency of these designer drugs places high demands on IAs regarding cross-reactivity of the antibodies used and detection limits. METHODS: Two retrospective studies were carried out in order to evaluate the capability of two homogenous enzyme IAs for the detection of currently prevalent SCs in authentic urine samples...
January 28, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28130893/perceptions-of-psychological-abuse-versus-physical-abuse-and-their-relationship-with-mental-health-outcomes
#20
B S Sandra F Masci, Sonya Sanderson
Prior research has been limited in examining at what degree aggressive actions are initially perceived negatively. Thepresent research examined whether anxiety, depression, and posttraumatic stress disorder (PTSD) symptoms were associated with prior abuse or with being attributed to past or present relationships. Scales such as the Dating Relationship Profile (DRP) and hypothetical scenarios of abuse perpetration were used. This study hypothesized that acceptability ratings from hypothetical scenarios would predict answers on DRP items measuring whether physical or psychological abuse is considered acceptable in relationships...
January 27, 2017: Violence and Victims
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