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https://www.readbyqxmd.com/read/28730160/epigenetic-interactions-between-alcohol-and-cannabinergic-effects-focus-on-histone-modification-and-dna-methylation
#1
Tiyash Parira, Alejandra Laverde, Marisela Agudelo
Epigenetic studies have led to a more profound understanding of the mechanisms involved in chronic conditions. In the case of alcohol addiction, according to the National Institute on Alcohol Abuse and Alcoholism, 16 million adults suffer from Alcohol Use Disorders (AUDs). Even though therapeutic interventions like behavioral therapy and medications to prevent relapse are currently available, no robust cure exists, which stems from the lack of understanding the mechanisms of action of alcohol and the lack of development of precision medicine approaches to treat AUDs...
April 2017: Journal of Alcoholism and Drug Dependence
https://www.readbyqxmd.com/read/28723265/a-text-mining-analysis-of-the-public-s-reactions-to-the-opioid-crisis
#2
Elizabeth M Glowacki, Joseph B Glowacki, Gary B Wilcox
BACKGROUND: Opioid abuse has become an epidemic in the United States. On August 25, 2016, the former Surgeon General of the United States sent an open letter to care providers asking for their help with combatting this growing health crisis. Social media forums like Twitter allow for open discussions among the public and up-to-date exchanges of information about timely topics like opioids. Therefore, the goal of the current study is to identify the public's reactions to the opioid epidemic by identifying the most popular topics tweeted by users...
July 19, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28705298/methamphetamine-related-disorders
#3
Euphrosyne Gouzoulis-Mayfrank, Roland Härtel-Petri, Willem Hamdorf, Ursula Havemann-Reinecke, Stephan Mühlig, Norbert Wodarz
BACKGROUND: Methamphetamine is considered more dangerous than other stimulants because of its acute complications, long-term neurotoxicity, and potential for drug dependence. Until now, there have been no evidence-based guidelines for the treatment of methamphetamine-related disorders, either in Germany or abroad. METHODS: A systematic literature search was performed on the treatment of methamphetamine-related disorders. Based on this literature review, a multidisciplinary expert panel developed recommendations using the nominal group technique...
June 30, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28692400/developing-syndromic-surveillance-to-monitor-and-respond-to-adverse-health-events-related-to-psychoactive-substance-use-methods-and-applications
#4
Michelle L Nolan, Hillary V Kunins, Ramona Lall, Denise Paone
INTRODUCTION: Recent increases in drug overdose deaths, both in New York City and nationally, highlight the need for timely data on psychoactive drug-related morbidity. We developed drug syndrome definitions for syndromic surveillance to monitor drug-related emergency department (ED) visits in real time. MATERIALS AND METHODS: We used 2012 archived syndromic surveillance data from New York City hospitals to develop definitions for psychoactive drug-related syndromes...
July 2017: Public Health Reports
https://www.readbyqxmd.com/read/28687475/double-jeopardy-predictors-of-elevated-lethality-risk-among-intimate-partner-violence-victims-seen-in-emergency-departments
#5
Laura Brignone, Anu Manchikanti Gomez
Many intimate partner homicide victims visit emergency departments (EDs) prior to their deaths, yet their lethality risk is not well understood. eHealth interventions for intimate partner violence (IPV) improve provider information, tailor care to victim need and link victims to services. We analyzed ED patients' lethality risk using one such intervention, Domestic Violence Report and Referral (DVRR). DVRR records were assessed for 263 female patients aged 16 and older seen for IPV at an urban, high-traffic, Northern California ED in 2014-15...
July 4, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28671025/a-typology-of-sex-offending-against-minors-an-empirical-study-of-rape-and-molestation-cases-in-china
#6
Bin Liang, Ming Hu
Efforts to classify sexual offending and offenders continued to evolve over the years based on criteria such as offender and victim characteristics, offender-victim relationships, the nature of sexual offenses, and other situational factors. This current study draws up a typology of sexual offending against minors based on 436 adjudicated rape and child molestation cases in China. Specifically, sexual offending against minors is classified into six major categories, including opportunistic offenses, serial offenses, dating couple offenses, educator abuses, gang/party offenses, and incest offenses...
June 1, 2017: Sexual Abuse: a Journal of Research and Treatment
https://www.readbyqxmd.com/read/28668759/adverse-childhood-experiences-among-youth-reported-to-child-welfare-results-from-the-national-survey-of-child-adolescent-wellbeing
#7
Antonio R Garcia, Meera Gupta, Johanna K P Greeson, Allison Thompson, Christina DeNard
The negative influence of adverse childhood experiences (ACEs) on social, emotional, and behavioral (SEB) outcomes are well documented. However, no research to date has examined the effect of ACEs on SEB outcomes in youth who received mental health services after reporting to the child welfare system. This study's analyses of data from the National Survey of Child and Adolescent Well-Being II revealed that the most prevalent ACEs included hospitalization for a medical condition, neglect, and exposures to domestic and community violence...
June 29, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28667832/effect-of-previous-posttraumatic-stress-in-the-perinatal-period
#8
Pamela A Geller, Emily C Stasko
OBJECTIVE: To review the extant literature on the effect of traumatic experiences that pre-date conception, pregnancy, and the postpartum period (perinatal period) and present a thematic overview of current issues in this relatively new area of inquiry. DATA SOURCES: Electronic databases CINAHL, PsychINFO, and PubMed were searched. Manual searches of bibliographies supplemented the electronic search. STUDY SELECTION: Peer-reviewed articles written in English on the role of posttraumatic stress disorder during the perinatal period were included...
June 28, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28661223/when-lying-changes-memory-for-the-truth
#9
Henry Otgaar, Alysha Baker
In the legal field, victims and offenders frequently lie to avoid talking about serious incidents, such as past experiences of sexual abuse or criminal involvement. Although these individuals may initially lie about an experienced event, oftentimes these same people eventually abandon their lies and are forthcoming with what truly happened. To date, it is unclear whether such lying affects later statements about one's memory for the experienced event. The impetus of the present review is to compile the current state of knowledge on the effects of lying on memory...
June 22, 2017: Memory
https://www.readbyqxmd.com/read/28658817/salient-features-of-a-proposed-adolescent-health-policy-draft-for-india
#10
Janmejaya Samal, Ranjit Kumar Dehury
India is one of the most populous countries in the world. The adolescent population in India constitutes about one fifth of the total Indian population. Adolescent phase is a transitional phase in life and the adolescents are neither child nor adult at this stage and are full of energy, have significant drive and new ideas. The relatively lower death rate and relatively good health status of the adolescents has always been a misleading measure to adolescent health and thus given lesser priorities. In order to respond effectively to the needs of adolescent health and development, it is important to place adolescence in a life-span perspective within dynamic sociological, cultural and economic realities...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28650185/sexual-misconduct-in-prison-what-factors-affect-whether-incarcerated-women-will-report-abuses-committed-by-prison-staff
#11
Sheryl P Kubiak, Hannah J Brenner, Deborah Bybee, Rebecca Campbell, Cristy E Cummings, Kathleen M Darcy, Gina Fedock, Rachael Goodman-Williams
More than 80,000 prisoners each year are sexually victimized during incarceration, but only about 8% report victimization to correctional authorities. Complicating reporting is the fact that half of the perpetrators are staff members. Given the restrictive and highly regulated prison environment, studies that examine reporting behaviors are difficult to conduct and to date information available relied on those who have reported or hypothetical victimization studies. This study uses an ecological framework and archival data from a class action lawsuit of sexual misconduct to determine predictors of reporting...
June 26, 2017: Law and Human Behavior
https://www.readbyqxmd.com/read/28649144/motivational-interviewing-or-counseling-medical-therapies-or-no-intervention-to-improve-tobacco-cessation-in-adults-and-adolescents
#12
Abigail R Norris, Jan E Miller
CLINICAL QUESTION: In adults and adolescents using cigarettes and/or smokeless tobacco, is motivational interviewing (MI) more effective compared to counseling, medical therapies or no intervention for improving tobacco cessation? ANSWER: Yes. Evidence is modest but conclusive that using MI alone or in conjunction with other therapies results in greater rates of tobacco cessation compared to interventions that did not include MI. LEVEL OF EVIDENCE OF THE ANSWER: A...
March 2017: Journal of the Oklahoma State Medical Association
https://www.readbyqxmd.com/read/28645961/cognitive-screening-and-behavioural-observation-of-functional-ability-in-patients-with-multiple-episode-schizophrenia-an-exploratory-study
#13
Eva Norlin Bagge, Eva Esbjörnsson, Katharina S Sunnerhagen
OBJECTIVES: To evaluate the usability of a neuropsychological screening instrument and two observation scales of everyday behaviour to describe cognitive and functional capacity of patients with multiepisode schizophrenia and considerable care needs, who frequently refuse to participate in cognitive testing or performance-based functional measurement. SETTING: One psychiatric unit specialised in severe mental illness at the Sahlgrenska University Hospital, Gothenburg, Sweden...
June 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28641534/interest-of-single-hair-analysis-to-document-drug-exposure-literature-review-and-a-case-report-involving-zuclopenthixol
#14
Nathalie Allibe, Pascal Kintz, Amandine Faure, François Paysant, Anne-Pascale Michard-Lenoir, Françoise Stanke-Labesque, Virginie Scolan, Hélène Eysseric-Guerin
The analysis of hair to detect drugs and drugs of abuse is performed in various contexts, including child protection cases, abstinence control programs, and workplace drug testing. This alternative matrix offers several advantages, such as a large detection window (months) and non-invasive collection. Segmental analysis of multiple hair strands for drugs and metabolites has been widely reported in the literature over the past three decades, whereas a review of the literature showed that there are only 26 articles that report the analysis of a single hair...
June 22, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28625767/early-life-stress-perturbs-the-function-of-microglia-in-the-developing-rodent-brain-new-insights-and-future-challenges
#15
REVIEW
Frances K Johnson, Arie Kaffman
The role of the innate immune system in mediating some of the consequences of childhood abuse and neglect has received increasing attention in recent years. Most of the work to date has focused on the role that neuroinflammation plays in the long-term adult psychiatric and medical complications associated with childhood maltreatment. The effects of stress-induced neuroinflammation on neurodevelopment have received little attention because until recently this issue has not been studied systematically in animal models of early life stress...
June 15, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28599850/tobacco-and-alcohol-use-during-adolescence-interactive-mechanisms-in-animal-models
#16
REVIEW
Yael Abreu-Villaça, Alex C Manhães, Thomas E Krahe, Claudio C Filgueiras, Anderson Ribeiro-Carvalho
There is a strong association between tobacco smoking and the consumption of alcoholic beverages. When compared to the effects of either drug on its own, the combined use may lead to worsened outcomes, such as less successful quitting attempts and increased likelihood of developing mood disorders. Co-consumption most frequently begins during adolescence, a developmental period that is characterized by an increased risk for substance use disorders. However, to date, most studies that have contributed to the current state of knowledge on the mechanisms that underlie tobacco or alcohol use/abuse, and their consequences, adopted adult animal models...
June 6, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/28592582/adverse-childhood-or-adult-experiences-and-risk-of-bilateral-oophorectomy-a-population-based-case-control-study
#17
Liliana Gazzuola Rocca, Carin Y Smith, Brandon R Grossardt, Stephanie S Faubion, Lynne T Shuster, Elizabeth A Stewart, Walter A Rocca
OBJECTIVES: Bilateral oophorectomy has commonly been performed in conjunction with hysterectomy even in women without a clear ovarian indication; however, oophorectomy may have long-term deleterious consequences. To better understand this surgical practice from the woman's perspective, we studied the possible association of adverse childhood or adult experiences with the subsequent occurrence of bilateral oophorectomy. DESIGN: Population-based case-control study...
June 7, 2017: BMJ Open
https://www.readbyqxmd.com/read/28582944/good-job-bad-job-the-employment-experiences-of-women-in-recovery-from%C3%A2-substance-abuse
#18
Joyce K Sinakhone, Bronwyn A Hunter, Leonard A Jason
BACKGROUND: Women in metropolitan areas have lower employment participation and employment rates than men. Although women face multiple challenges in the labor market, those who have a history of substance use and are abstinent may have a greater disadvantage in obtaining viable employment opportunities due to factors associated with substance use. No research to date has examined employment experiences among women in recovery from substance use. OBJECTIVE: This study examined employment characteristics and experiences of women who had a history of substance use and lived in sober-living environments in urban areas...
June 1, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28582653/gender-matters-experiences-and-consequences-of-digital-dating-abuse-victimization-in-adolescent-dating-relationships
#19
Lauren A Reed, Richard M Tolman, L Monique Ward
Digital dating abuse (DDA) behaviors include the use of digital media to monitor, control, threaten, harass, pressure, or coerce a dating partner. In this study, 703 high school students reported on the frequency of DDA victimization, whether they were upset by these incidents, and how they responded. Results suggest that although both girls and boys experienced DDA at similar rates of frequency (with the exception of sexual coercion), girls reported that they were more upset by these behaviors. Girls also expressed more negative emotional responses to DDA victimization than boys...
August 2017: Journal of Adolescence
https://www.readbyqxmd.com/read/28581646/triangulation-and-parent-adolescent-relationships-implications-for-adolescent-dating-competence-and-abuse
#20
Gregory M Fosco, Mengya Xia, Mark G Lynn, John H Grych
This study focuses on family predictors of conflict behavior in adolescent dating relationships, drawing on family systems and socialization perspectives. Mother-adolescent, father-adolescent, and triadic relationships each was examined as predictors of adolescent dating outcomes that hold importance for developmental and prevention science (positive conflict resolution, verbal abuse, and physical abuse). We conducted a longitudinal analysis using a 6-month longitudinal design with 236 ethnically diverse high school students...
September 2016: Journal of Research on Adolescence: the Official Journal of the Society for Research on Adolescence
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