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https://www.readbyqxmd.com/read/28822746/outcomes-of-early-adolescent-donor-hearts-in-adult-transplant-recipients
#1
Shivank Madan, Snehal R Patel, Peter Vlismas, Omar Saeed, Sandhya Murthy, Stephen Forest, William Jakobleff, Daniel Sims, Jacqueline M Lamour, Daphne T Hsu, Julia Shin, Daniel Goldstein, Ulrich P Jorde
OBJECTIVES: This study sought to determine outcomes of adult recipients of early adolescent (EA) (10 to 14 years) donor hearts. BACKGROUND: Despite a shortage of donor organs, EA donor hearts (not used for pediatric patients) are seldom used for adults because of theoretical concerns for lack of hormonal activation and changes in left ventricular mass. Nonetheless, the outcomes of adult transplantation using EA donor hearts are not clearly established. METHODS: All adult (≥18 years of age) heart transplant recipients in the United Network for Organ Sharing database between April 1994 and September 2015 were eligible for this analysis...
August 3, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28822514/anthropometric-indicators-as-predictor-of-pre-diabetes-in-indian-adolescents
#2
Umeshwar Pandey, Tanu Midha, Yashwant Kumar Rao, Pravin Katiyar, Pranay Wal, Samarjeet Kaur, Dinesh Singh Martolia
INTRODUCTION: In India, there are approximately 41 million diabetics to date. Impaired glucose tolerance or pre-diabetes may occur as early as adolescence. OBJECTIVE: To find out the cut-off values of body mass index (BMI) and waist circumference to predict pre-diabetes in adolescents in north India. METHODS: A cross-sectional study was conducted among 526 students aged 17-19 years, in the Institute of Paramedical Sciences, Chatrapati Shahuji Maharaj University, Kanpur...
July 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28818770/hereditary-multiple-exostoses-as-a-novel-cause-of-bilateral-popliteal-artery-aneurysms-in-the-elderly
#3
Eliza J Ferrari, Rory K Crotty, Katharina Eikermann-Haerter, James R Stone
Hereditary multiple exostoses (HME) is a genetic condition characterized by the development of multiple osteochondromas during childhood and adolescence. On rare occasions, these bony tumors can be associated with vascular injury, most commonly involving the popliteal artery. Such patients typically present with vascular complications in adolescence and young adulthood. We report an autopsy study of an elderly man who presented with bilateral popliteal artery pseudoaneurysms in the setting of HME at age 81...
July 8, 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/28818416/adolescent-sports-participation-e-cigarette-use-and-cigarette-smoking
#4
Phil Veliz, Sean Esteban McCabe, Vita V McCabe, Carol J Boyd
INTRODUCTION: Although sport participation among adolescents has been found to lower the risk of traditional cigarette smoking, no studies to date have assessed if this type of physical activity lowers the risk of e-cigarette use among adolescents. METHODS: National data from the 2014 and 2015 Monitoring the Future study of 12th-grade students were used and analyses were conducted in 2016. Measures for past 30-day e-cigarette use and traditional cigarette smoking were used to assess differences between adolescents who participated in at least one competitive sport during the past year and adolescents who did not...
August 14, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28815331/meta-analysis-of-the-long-term-treatment-effects-of-psychological-interventions-in-youth-with-ptsd-symptoms
#5
REVIEW
Jana Gutermann, Laura Schwartzkopff, Regina Steil
To date, the long-term effectiveness of psychological treatments in reducing post-traumatic stress disorder symptoms in children and adolescents has not been investigated extensively. This meta-analysis quantifies the long-term effects of psychological interventions in children and adolescents with PTSD symptoms and examines the period-dependent follow-up (FU) effects based on 47 studies. The mean FU effect sizes (ESs) for PTSD symptoms ranged from medium (between treatment ESs for controlled studies) to large (within treatment ESs for uncontrolled studies; pooled analysis including all studies)...
August 16, 2017: Clinical Child and Family Psychology Review
https://www.readbyqxmd.com/read/28814369/intraosseous-leiomyoma-of-the-jaw-in-an-adolescent
#6
Adaia Valls-Ontañón, Laura Pozuelo-Arquimbau, Gemma Mateu-Esquerda, Carlos Arranz-Obispo, Sílvia Cuscó-Albors, Mireia Melero-Luque, Arnaud Morla, Antoni Marí-Roig
Leiomyoma is a benign tumor of the smooth muscle that rarely occurs in the mouth as an intraosseous lesion. The purposes of this paper are to: (1) present a case of an intraosseous solid leiomyoma of the mandible in a 13-year-old child, who presented with a well-defined unilocular radiolucency in the right mandible incidentally discovered during a routine dental radiographic examination; and (2) conduct a review of the literature to describe clinicopathological features and management of intraosseous jaw leiomyoma (IJL)...
May 15, 2017: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/28812816/the-challenges-of-projecting-the-public-health-impacts-of-marijuana-legalization-in-canada-comment-on-legalizing-and-regulating-marijuana-in-canada-review-of-potential-economic-social-and-health-impacts
#7
Stephanie Lake, Thomas Kerr
A recent editorial in this journal provides a summary of key economic, social, and public health considerations of the forthcoming legislation to legalize, regulate, and restrict access to marijuana in Canada. As our government plans to implement an evidence-based public health framework for marijuana legalization, we reflect and expand on recent discussions of the public health implications of marijuana legalization, and offer additional points of consideration. We select two commonly cited public concerns of marijuana legalization - adolescent usage and impaired driving - and discuss how the underdeveloped and equivocal body of scientific literature surrounding these issues limits the ability to predict the effects of legalization...
September 10, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28810945/teen-dating-violence-predicting-physical-and-sexual-violence-and-mental-health-symptoms-among-heterosexual-adolescent-males
#8
Peter Fawson, Timothy Jones, Bobby Younce
This study investigated the prevalence of female-to-male intimate partner violence (IPV) and mental health symptoms among 589 male high school students. Participants completed questionnaires asking if they had experienced dating violence victimization, mental health symptoms, and violent attitudes. Correlations revealed strong positive associations between sexual, physical, and psychological IPV among male victims. Multiple regression found significant predictors of negative mental health consequences were experiencing psychological violence, experiencing physical violence, and having attitudes that accept violence...
August 15, 2017: Violence and Victims
https://www.readbyqxmd.com/read/28807769/reduced-intensity-haploidentical-bone-marrow-transplantation-with-post-transplant-cyclophosphamide-for-solid-tumors-in-pediatric-and-young-adult-patients
#9
Nicolas J Llosa, Kenneth R Cooke, Allen Chen, Christopher Gamper, Orly Klein, Elias Zambidis, Brandon Luber, Gary Rosner, Nicholas Siegel, Mary Jo Holuba, Nancy Robey, Masanori Hayashi, Richard J Jones, Ephraim Fuchs, Matthias Holdhoff, David M Loeb, Heather J Symons
High risk, recurrent, or refractory solid tumors in pediatric, adolescent and young adult (AYA) patients have an extremely poor prognosis despite current intensive treatment regimens. We piloted an allogeneic bone marrow transplant (alloBMT) platform using a reduced intensity conditioning (RIC) and partially HLA-mismatched (haploidentical) related donors for this population of pediatric and AYA solid tumor patients. Sixteen patients received a fludarabine, cyclophosphamide (Cy), melphalan and low dose total body irradiation (TBI) RIC haploidentical BMT (haploBMT) followed by post-transplantation cyclophosphamide (PTCy), mycophenolate mofetil (MMF) and sirolimus...
August 11, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28803504/the-pharmacological-management-of-nafld-in-children-and-adolescents
#10
Savinda Liyanagedera, Robert Patrick Williams, Silvio Veraldi, Valerio Nobili, Jake P Mann
Non-alcoholic fatty liver disease (NAFLD) represents a spectrum, including 'simple' steatosis, non-alcoholic steatohepatitis (NASH), and fibrosis. Increasing prevalence of NAFLD has followed the international rise in obesity and lifestyle modification is the mainstay therapy for children. To date, pharmacological trials have had varying efficacy but a large number of new agents are in early phase trials for adults. Areas covered: This review explores the effect of current and potential future paediatric NAFLD treatments in terms of histological and biochemical endpoints...
August 21, 2017: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/28801730/prospective-changes-in-neural-alcohol-cue-reactivity-in-at-risk-adolescents
#11
Tam T Nguyen-Louie, Kelly E Courtney, Lindsay M Squeglia, Kara Bagot, Sonja Eberson, Robyn Migliorini, Alexis R Alcaraz, Susan F Tapert, Carmen Pulido
Adolescence represents an ideal time for elucidating the etiology of cue reactivity profiles. This study examined the influence of three risk factors consistently associated with heavy adolescent drinking on alcohol cue reactivity. Youth were first assessed while still naïve to alcohol (12-14 years old) and followed after transitioning into alcohol use (17-21 years old). The effects of family history of substance use disorder, sex, and history of early of dating (i.e., before 14 years of age) on BOLD response contrast to alcohol picture cues were examined in a linear mixed model, controlling for age and alcohol use patterns at follow-up...
August 11, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28801423/comparative-efficacy-and-acceptability-of-antidepressants-psychological-interventions-and-their-combination-for-depressive-disorder-in-children-and-adolescents-protocol-for-a-network-meta-analysis
#12
Xinyu Zhou, Andrea Cipriani, Yuqing Zhang, Pim Cuijpers, Sarah E Hetrick, John R Weisz, Juncai Pu, Cinzia Del Giovane, Toshiaki A Furukawa, Jürgen Barth, David Coghill, Stefan Leucht, Lining Yang, Arun V Ravindran, Peng Xie
INTRODUCTION: Depressive disorder is common in children and adolescents, with important consequences and serious impairments in terms of personal and social functioning. While both pharmacological and psychological interventions have been shown to be effective, there is still uncertainty about the balance between these and what treatment strategy should be preferred in clinical practice. Therefore, we aim to compare and rank in a network meta-analysis (NMA) the commonly used psychological, pharmacological and combined interventions for depressive disorder in children and adolescents...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28800060/relationship-between-physical-activity-level-and-psychosocial-and-socioeconomic-factors-and-issues-in-children-and-adolescents-with-asthma-a-scoping-review
#13
Thomas Westergren, Sveinung Berntsen, Mette Spliid Ludvigsen, Hanne Aagaard, Elisabeth O C Hall, Yngvar Ommundsen, Lisbeth Uhrenfeldt, Liv Fegran
BACKGROUND: Asthma is a heterogeneous chronic airway disease which may reduce capability for physical activity. In healthy peers, physical activity is influenced by psychosocial and socioeconomic factors. Knowledge about the role of these factors has not been mapped in children and adolescents with asthma. OBJECTIVE: The main objective of this scoping review was to identify psychosocial and socioeconomic factors associated with physical activity level in children and adolescents with asthma in the literature...
August 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28795347/health-related-quality-of-life-in-individuals-with-down-syndrome-results-from-a-non-interventional-longitudinal-multi-national-study
#14
Diana Rofail, Daniel Froggatt, Rafael de la Torre, Jamie Edgin, Priya Kishnani, Renaud Touraine, Sarah Whitwham, Lisa Squassante, Omar Khwaja, Xavier Liogier D'Ardhuy
INTRODUCTION: To date, there is little research on health-related quality of life (HRQoL) in Down syndrome (DS), and existing research is variable with regard to reported HRQoL in DS. There are also no HRQoL measures developed specifically to be used with individuals with Down syndrome. METHODS: A multi-national, longitudinal, 24-week non-interventional study was conducted in adolescents and adults with DS. HRQoL was assessed (n = 90) using the parent-report KIDSCREEN-27 questionnaire...
August 9, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28794052/pediatric-match-trial-opens-enrollment
#15
(no author information available yet)
The largest basket study to date of targeted agents in children and adolescents began enrolling patients in late July. Pediatric MATCH will study seven drugs to start; researchers plan to add at least two more in the near future.
August 9, 2017: Cancer Discovery
https://www.readbyqxmd.com/read/28791542/etiology-of-teen-dating-violence-among-adolescent-children-of-alcoholics
#16
Jennifer A Livingston, Rina D Eiden, Jared Lessard, Meghan Casey, James Henrie, Kenneth E Leonard
Family processes in early life have been implicated in adolescent involvement in teen dating violence, yet the developmental pathways through which this occurs are not well understood. In this study, etiological pathways from parental psychopathology and marital conflict in infancy to involvement in dating violence in late adolescence were examined in a sample of children at high-risk due to parental alcohol problems. Families (N = 227) recruited when the child was 12 months of age were assessed at 12-, 24-, 36-months, kindergarten, 6th, 8th, and 12th grades...
August 8, 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/28777175/non-rapid-eye-movement-sleep-and-overlap-parasomnias
#17
Muna Irfan, Carlos H Schenck, Michael J Howell
PURPOSE OF REVIEW: This article reviews the spectrum of non-rapid eye movement (non-REM) sleep parasomnias, including sleepwalking, confusional arousals, and sleep terrors, which represent the range of phenotypic disorders of arousal from non-REM sleep that occurs in children and adults. RECENT FINDINGS: The International Classification of Sleep Disorders, Third Edition (ICSD-3) classifies parasomnias according to the sleep stage they emerge from: REM, non-REM, or other...
August 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28768492/the-effect-of-youth-assertive-community-treatment-a-systematic-prisma-review
#18
Richard Vijverberg, Robert Ferdinand, Aartjan Beekman, Berno van Meijel
BACKGROUND: During the past decades deinstitutionalisation policies have led to a transition from inpatient towards community mental health care. Many European countries implement Assertive Community Treatment (ACT) as an alternative for inpatient care for "difficult to reach" children and adolescents with severe mental illness. ACT is a well-organized low-threshold treatment modality; patients are actively approached in their own environment, and efforts are undertaken to strengthen the patient's motivation for treatment...
August 2, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28767962/cyber-dating-abuse-in-affective-and-sexual-relationships-a-literature-review
#19
Roberta Matassoli Duran Flach, Suely Ferreira Deslandes
Cyber culture with its related e-commerce, expanded since the 2000s through the advent of social network platforms, incites participants to engage in hyper-exposure and spectacularization of their private lives, with inherent consequences for personal image and privacy, publicizing private matters (especially those pertaining to sexuality and corporality) in the digital media. This raises the need to understand how the phenomenon of cyber dating abuse in affective and sexual relationships is conceptualized and characterized in scientific studies, which health problems are associated with it, and which social technologies are suggested for intervention...
July 27, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28766318/teen-dating-violence-victimization-among-high-school-students-a-multilevel-analysis-of-school-level-risk-factors
#20
Elizabeth M Parker, Sarah Lindstrom Johnson, Katrina J Debnam, Adam J Milam, Catherine P Bradshaw
BACKGROUND: Much etiologic research has focused on individual-level risk factors for teen dating violence (TDV); therefore, less is known about school-level and neighborhood-level risk factors. We examined the association between alcohol outlet density around high schools and TDV victimization and the association between markers of physical disorder around schools and TDV victimization among adolescents. METHODS: Data come from high school students participating in the Maryland Safe and Supportive Schools Initiative...
September 2017: Journal of School Health
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