Yi Nong, Eike Steinig, Georgina L Pollock, George Taiaroa, Glen P Carter, Ian R Monk, Stanley Pang, Denise A Daley, Geoffrey W Coombs, Brian M Forde, Patrick N A Harris, Norelle L Sherry, Benjamin P Howden, Shivani Pasricha, Sarah L Baines, Deborah A Williamson
The past decade has seen an increase in the prevalence of sequence type (ST) 45 methicillin-resistant Staphylococcus aureus (MRSA), yet the underlying drivers for its emergence and spread remain unclear. To better understand the worldwide dissemination of ST45 S. aureus, we performed phylogenetic analyses of Australian isolates, supplemented with a global population of ST45 S. aureus genomes. Our analyses revealed a distinct lineage of multidrug-resistant ST45 MRSA harbouring qacA, predominantly found in Australia and Singapore...
March 21, 2024: Communications Biology