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https://www.readbyqxmd.com/read/28922026/characterization-of-quinolone-resistance-in-salmonella-enterica-from-farm-animals-in-china
#1
Ting-Ting Cao, Guo-Hui Deng, Liang-Xing Fang, Run-Shi Yang, Jian Sun, Ya-Hong Liu, Xiao-Ping Liao
This study was focused on the prevalence and antimicrobial susceptibilities of Salmonella directly isolated at animal clinics in Guangdong, People's Republic of China. The isolation rates from chickens, ducks, and pigs were 11.3% (11 of 97 samples), 15.4% (53 of 344 samples), and 3.0% (13 of 434 samples), respectively. Among the 77 Salmonella enterica isolates, the most predominant serovar was Typhimurium (81.8%, 63 isolates), followed by serovars Meleagridis (2.6%, 2 isolates) and Abaetetuba (1.3%, 1 isolate)...
September 18, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28920749/american-association-of-clinical-endocrinologists-and-american-college-of-endocrinology-disease-state-commentary-managing-thyroid-tumors-diagnosed-as-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features
#2
Zubair W Baloch, R Mack Harrell, Elise M Brett, Gregory Randolph, Jeffrey R Garber
This commentary summarizes the history and reclassification of noninvasive follicular thyroid neoplasm with papillary-like nuclei (NIFTP). It reviews the salient histopathologic features that are based on immunohistochemical and molecular profiles and serve as inclusion and exclusion criteria. The authors also provide their own point of view regarding the practical issues and possible concerns that may be raised by both clinicians and patients based on the diagnosis of NIFTP. ABBREVIATIONS: AACE = American Association of Clinical Endocrinologists EFVPTC = encapsulated FVPTC FNA = fine-needle aspiration FVPTC = follicular variant of papillary thyroid carcinoma NIFTP = noninvasive follicular thyroid neoplasm with papillary-like nuclear features PTC = papillary thyroid carcinoma...
September 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28916480/factors-associated-with-zonular-instability-during-cataract-surgery-in-eyes-with-acute-angle-closure-attack
#3
Junki Kwon, Kyung Rim Sung
PURPOSE: To compare the demographics and ocular characteristics, including anterior segment optical coherence tomography images and zonular instability in eyes with a history of acute angle closure (AAC) attack and subsequent cataract surgery. DESIGN: Retrospective, case-control study METHODS: Total 68 eyes of 56 patients with a history of AAC attack who underwent cataract surgery were enrolled. Fourteen eyes were assigned to the zonular instability (+) group and 54 were assigned to the zonular instability (-) group based on the presence of zonular instability during cataract surgery...
September 12, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28912764/resistance-to-antibiotics-biocides-preservatives-and-metals-in-bacteria-isolated-from-seafoods-co-selection-of-strains-resistant-or-tolerant-to-different-classes-of-compounds
#4
José L Romero, María J Grande Burgos, Rubén Pérez-Pulido, Antonio Gálvez, Rosario Lucas
Multi-drug resistant bacteria (particularly those producing extended-spectrum β-lactamases) have become a major health concern. The continued exposure to antibiotics, biocides, chemical preservatives, and metals in different settings such as the food chain or in the environment may result in development of multiple resistance or co-resistance. The aim of the present study was to determine multiple resistances (biocides, antibiotics, chemical preservatives, phenolic compounds, and metals) in bacterial isolates from seafoods...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28893357/fluoroquinolone-resistance-in-extended-spectrum-%C3%AE-lactamase-producing-klebsiella-pneumoniae-in-a-japanese-tertiary-hospital-silent-shifting-to-ctx-m-15-producing-k-pneumoniae
#5
Masashi Higashino, Mika Murata, Yoshitomo Morinaga, Norihiko Akamatsu, Junichi Matsuda, Kazuaki Takeda, Norihito Kaku, Kosuke Kosai, Naoki Uno, Hiroo Hasegawa, Katsunori Yanagihara
PURPOSE: Fluoroquinolone resistance (FQ-r) in extended-spectrum β-lactamase (ESBL) producers is an urgent health concern in countries where ESBL-producing K. pneumoniae (ESBL-Kpn) is prevalent. We investigated FQ-r in Japan where ESBL-Kpn is less prevalent. METHODOLOGY: Clinical ESBL-Kpn isolates from 2011 to 2013 were collected in Nagasaki University Hospital. The ESBL genotypes included CTX-M-15, and the mechanisms of FQ-r through plasmid-mediated quinolone resistance (PMQR) and mutations in quinolone resistance-determining regions (QRDRs) were examined...
September 12, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28889401/severity-of-drug-resistance-and-co-existence-of-enterococcus-faecalis-in-diabetic-foot-ulcer-infections
#6
Kavitha Shettigar, Deepika V Bhat, Kapaettu Satyamoorthy, Thokur Sreepathy Murali
The genes encoding aminoglycoside resistance in Enterococcus faecalis may promote collateral aminoglycoside resistance in polymicrobial wounds. We studied a total of 100 diabetic foot ulcer samples for infection and found 60 samples to be polymicrobial, 5 to be monomicrobial, and 35 samples to be culture negative. A total of 65 E. faecalis isolates were screened for six genes coding for aminoglycoside resistance, antibiotic resistance patterns, and biofilm production. Infectious Diseases Society of America/International Working Group on the Diabetic Foot system was used to classify the wound ulcers...
September 9, 2017: Folia Microbiologica
https://www.readbyqxmd.com/read/28888884/prevalence-of-antimicrobial-resistance-and-integron-gene-cassettes-in-escherichia-coli-isolated-from-yaks-poephagus-grunniens-in-aba-tibetan-autonomous-prefecture-china
#7
Xin Yang, Wencheng Zou, Jinxin Zeng, Shengze Xie, Tianwu An, Xiaolin Luo, Danyu Chen, Lan Feng, Guangyang Cheng, Run Cai, Qianru Huang, Hongning Wang
BACKGROUND: Escherichia coli (E. coli) is one of the most relevant opportunistic pathogenic bacteria as it may cause severe morbidity and mortality in yaks (poephagus grunniens). In recent years, several kinds of antibiotics have been widely used in Tibetan areas to treat the bacterial diseases, resulting in serious repercussions on the bacterial antibiotic resistance in yaks. This investigation was conducted in order to determine the prevalence of antimicrobial resistance and integron gene cassettes in E...
September 6, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28885674/the-outcome-of-transscleral-cyclophotocoagulation-for-the-management-of-acute-angle-closure
#8
Patrick J Chiam, Velota C T Sung
PURPOSE: To investigate the outcome of transscleral cyclophotocoagulation (TCP) in the treatment of acute angle closure (AAC) refractory to medical treatment. METHODS: This is a retrospective interventional case series. The inclusion criteria include patients diagnosed with AAC who had TCP. Pre-TCP and post-TCP intraocular pressure (IOP), visual acuity, and AAC treatment were analyzed. The complications and the results of subsequent treatments including lens extraction if performed were also assessed...
September 7, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28884601/systematic-review-of-aac-intervention-research-for-adolescents-and-adults-with-autism-spectrum-disorder
#9
Christine Holyfield, Kathryn D R Drager, Jennifer M D Kremkow, Janice Light
Much of augmentative and alternative communication (AAC) research for individuals with autism spectrum disorder has focused on young children. Given that the lives, communication, strengths, and needs of adolescents and adults with autism spectrum disorder are quite different from those of young children, the purpose of the current study was to consolidate current AAC intervention research findings specific to these individuals. A systematic review was conducted to identify and evaluate relevant research. Results indicate that AAC intervention benefits adolescents and adults with autism spectrum disorder...
September 8, 2017: Augmentative and Alternative Communication: AAC
https://www.readbyqxmd.com/read/28882450/the-8-oxo-deoxyguanosine-glycosylase-increases-its-migration-to-mitochondria-in-compensated-cardiac-hypertrophy
#10
Jorge E Vela-Guajardo, Perla Pérez-Treviño, Irais Rivera-Álvarez, Fabio A González-Mondellini, Julio Altamirano, Noemí García
Cardiac hypertrophy is a compensatory mechanism maladapted because it presents an increase in the oxidative stress which could be associated with the development of the heart failure. A mechanism proposed is by mitochondrial DNA (mtDNA) oxidation, which evolved to a vicious cycle because of the synthesis of proteins encoded in the genome is committed. Therefore, the aim of the present work was to evaluate the mtDNA damage and enzyme repairing the 8-oxo-deoxyguanosine glycosylase mitochondrial isoform 1-2a (OGG1-2a) in the early stage of compensated cardiac hypertrophy induced by abdominal aortic constriction (AAC)...
August 24, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28878891/epidemic-characterization-and-molecular-genotyping-of-shigella-flexneri-isolated-from-calves-with-diarrhea-in-northwest-china
#11
Zhen Zhu, Mingze Cao, Xuzheng Zhou, Bing Li, Jiyu Zhang
BACKGROUND: The widespread presence of antibiotics resistance genes in pathogenic bacteria can cause enormous problems. Food animals are one of the main reservoirs of intestinal pathogens that pose a potential risk to human. Analyzing the epidemiological characteristics and resistance patterns of Shigella flexneri in calves is necessary for animal and human health. METHODS AND RESULTS: A total of 54 Shigella flexneri isolates, including six serotypes (1a, 2a, 2b, 4a, 6 and Xv), were collected from 837 fecal samples obtained from 2014 to 2016...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/28876251/removal-of-phosphorus-using-suspended-reactive-filters-srfs-efficiency-and-potential-applications
#12
Agnieszka Karczmarczyk, Agnieszka Bus
The removal of phosphorus (P) from agricultural runoff is essential to reduce the threat of eutrophication in bodies of water. In this study, an alternative method of applying P reactive materials (RMs) in the form of suspended reactive filters (SRFs) is presented. The SRF method enables P which has already entered a body of water to be caught. In this study, an autoclaved aerated concrete (AAC) was used as the SRFs. The experiment was carried out in a laboratory in a hydraulic block of 1 m in width and 2 m in length...
September 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28874544/single-rat-muscle-na-channel-mutation-confers-batrachotoxin-autoresistance-found-in-poison-dart-frog-phyllobates-terribilis
#13
Sho-Ya Wang, Ging Kuo Wang
Poison-dart Phyllobates terribilis frogs sequester lethal amounts of steroidal alkaloid batrachotoxin (BTX) in their skin as a defense mechanism against predators. BTX targets voltage-gated Na(+) channels and enables them to open persistently. How BTX autoresistance arises in such frogs remains a mystery. The BTX receptor has been delineated along the Na(+) channel inner cavity, which is formed jointly by four S6 transmembrane segments from domains D1 to D4. Within the P. terribilis muscle Na(+) channel, five amino acid (AA) substitutions have been identified at D1/S6 and D4/S6...
September 5, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28873825/exploring-the-perspectives-of-people-who-use-alternative-and-augmentative-communication-aids-aac
#14
Katherine Broomfield, Karen Sage
This paper outlines the clinical doctoral research plan (funded by HEE/NIHR Integrated Clinical Academic Programme) to engage the wide range of people who use alternative and augmentative communication (AAC) to understand the perspectives of users in order to develop a Patient Reported Outcome Measure (PROM) to evaluate equipment and services.
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28873824/optimising-service-delivery-of-aac-at-devices-and-compensating-at-for-dyslexia
#15
Uta R Roentgen, Edith A V Hagedoren, Katrien D L Horions, Ruth J P Dalemans
To promote successful use of Assistive Technology (AT) supporting Augmentative and Alternative Communication (AAC) and compensating for dyslexia, the last steps of their provision, delivery and instruction, use, maintenance and evaluation, were optimised. In co-creation with all stakeholders based on a list of requirements an integral method and tools were developed.
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28873823/democratisation-of-aac-symbol-choices-using-technology
#16
E A Draffan, Mike Wald, Nadine Zeinoun, David Banes
The use of an online voting system has been developed to enable democratic choices of newly designed symbols to support speech, language and literacy skills in a localisation situation. The system works for those using and supporting Augmentative and Alternative Communication (AAC) symbols on electronic systems by the provision of simplified scales of acceptance and adapted grids. The methodology and results highlighted the importance of user participation at the outset and concrete examples of symbol adaptations that were found necessary to ensure higher levels of user satisfaction...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28873819/analysis-of-an-individual-s-language-to-improve-efficiency-of-an-aac-system
#17
Will Wade, Heidi Koester, Samantha McNeilly
The paper discusses the collection and analysis of a three-month language sample from an adult using a low-tech augmentative and alternative communication (AAC) system transcribed to analyse the frequency of words and letters to make suggestions for more efficiency.
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28872819/a-facile-approach-to-prepare-tough-and-responsive-ultrathin-physical-hydrogel-films-as-artificial-muscles
#18
Ye Tian, Xiaoshuang Wei, Zhi Jian Wang, Pengju Pan, Fangyuan Li, Daishun Ling, Zi Liang Wu, Qiang Zheng
We report a facile approach to prepare ultrathin physical hydrogel films based on Marangoni effect, which drives ethanol solution of poly(stearyl acrylate-co-acrylic acid) (P(SA-co-AAc)) to rapidly spread on water surface. The subsequent solvent exchange leads to sol-gel transition, where the long alkyl chains of SA units segregate to form physical crosslinking junctions. The resultant disk-shaped single-network (SN) gel films are uniform with tunable thickness (40-80 μm) and diameter (5-12 cm), and possess robust mechanical properties with tensile breaking stress, εb, and breaking strain, εb, being 0...
September 5, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28870291/genomic-characterization-of-an-extensively-drug-resistance-salmonella-enterica-serotype-indiana-strain-harboring-blandm-1-gene-isolated-from-a-chicken-carcass-in-china
#19
Wei Wang, Zixin Peng, Zulqarnain Baloch, Yujie Hu, Jin Xu, Wenhui Zhang, Séamus Fanning, Fengqin Li
OBJECTIVES: The objective of this study was to genetically characterize the antimicrobial resistance mechanisms of Salmonella enterica serotype Indiana C629 isolated from a chicken carcass in China in 2014. METHODS: Antimicrobial susceptibility against a panel of 23 antimicrobial agents was carried out on Salmonella enterica serotype Indiana C629 and assessed according to CLSI standards. Whole-genome sequencing of this isolate was conducted to obtain the complete genome of S...
November 2017: Microbiological Research
https://www.readbyqxmd.com/read/28870151/progression-of-arterial-stiffness-is-associated-with-changes-in-bone-mineral-markers-in-advanced-ckd
#20
Rathika Krishnasamy, Sven-Jean Tan, Carmel M Hawley, David W Johnson, Tony Stanton, Kevin Lee, David W Mudge, Scott Campbell, Grahame J Elder, Nigel D Toussaint, Nicole M Isbel
BACKGROUND: Arterial stiffness is an independent predictor of all-cause and cardiovascular mortality in patients with chronic kidney disease (CKD). There are limited prospective data however on progression of arterial stiffness in CKD, including evaluating associations with bone mineral markers such as fibroblast growth factor 23 (FGF23) and soluble α-klotho (sKl). METHODS: In this prospective, single-center, observational study, arterial stiffness [measured by pulse wave velocity (PWV)] and hormones influencing mineral homeostasis, including serum FGF23 and sKl, were compared between non-dialysis CKD stages 4/5 and healthy controls at baseline and 12 months (12 m)...
September 4, 2017: BMC Nephrology
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