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https://www.readbyqxmd.com/read/27913068/occult-infratemporal-fossa-neurofibroma-presenting-with-persistent-unilateral-tinnitus-and-middle-ear-effusion-more-than-meets-the-eye
#1
Lucas P Carlstrom, Kathryn M Van Abel, Matthew L Carlson, Eric J Moore, Janalee K Stokken
Herein, we present the case of a previously healthy 54year-old female who developed several weeks of unilateral tinnitus and aural fullness. She subsequently underwent unilateral pressure equalization tube placement at an outside institution after exam demonstrated a middle ear effusion, conductive hearing loss and normal nasopharyngoscopy. Ultimately, an MRI revealed an occult mass in the infratemporal fossa (ITF), which was successfully removed via an endoscopic transnasal ITF approach. Following resection of a histopathologically confirmed benign neurofibroma, she reported complete resolution of her symptoms...
November 23, 2016: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/27911234/ventriculostomy-associated-hemorrhage-a-risk-assessment-by-radiographic-simulation
#2
Faith C Robertson, Muhammad M Abd-El-Barr, Srinivasan Mukundan, William B Gormley
OBJECTIVE Ventriculostomy entry sites are commonly selected by freehand estimation of Kocher's point or approximations from skull landmarks and a trajectory toward the ipsilateral frontal horn of the lateral ventricles. A recognized ventriculostomy complication is intracranial hemorrhage from cortical vessel damage; reported rates range from 1% to 41%. In this report, the authors assess hemorrhagic risk by simulating traditional ventriculostomy trajectories and using CT angiography (CTA) with venography (CTV) data to identify potential complications, specifically from cortical draining veins...
December 2, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27908187/dosimetric-characterization-of-mri-only-treatment-planning-for-brain-tumors-in-atlas-based-pseudo-ct-images-generated-from-standard-t1-weighted-mr-images
#3
Benjamin Demol, Christine Boydev, Juha Korhonen, Nick Reynaert
PURPOSE: Magnetic resonance imaging (MRI)-only radiotherapy treatment planning requires accurate pseudo-CT (pCT) images for precise dose calculation. The current work introduced an atlas-based method combined with MR intensity information. pCT analyses and Monte Carlo dose calculations for intracranial stereotactic treatments were performed. METHODS: Twenty-two patients, representing 35 tumor targets, were scanned using a 3D T1-weighted MRI sequence according to the clinical protocol...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27906848/calculation-of-an-optic-nerve-injury-risk-profile-before-sphenoid-sinus-surgery
#4
Erdem Atalay Cetinkaya, Koray Koc, Mehmet Fatih Kucuk, Pinar Koc, Nuray Bayar Muluk, Cemal Cingi
OBJECTIVES: Our objective was to analyze variations in the optic nerve (ON) course and surrounding structures in an effort to construct an optic nerve injury risk profile before endoscopic intranasal sphenoidal, or endoscopic endonasal transphenoidal, skull-base surgery, and eventually to construct and formulate a common classification by combining the known classes. The authors used computed tomography (CT) toward this end. METHODS: The authors retrospectively reviewed 200 consecutive CT scans (400 sides) of the paranasal sinuses...
November 30, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27906102/radiation-induced-osteosarcoma-of-the%C3%A2-skull-base-after-radiation-therapy-in-a-patient-with-nasopharyngeal-carcinoma-a%C3%A2-case-report-and-review-of-the%C3%A2-literature
#5
Yassine Echchikhi, Hasna Loughlimi, Asmae Touil, Tayeb Kebdani, Noureddine Benjaafar
BACKGROUND: Radiation-induced osteosarcomas are a recognized complication of radiation therapy. Owing to the fact that it is rare, publications on radiation-induced osteosarcoma of the skull base are limited to a small series and some case reports. CASE PRESENTATION: We describe a rare case of a patient with a skull base radiation-induced osteosarcoma treated 11 years before with ionizing radiation for an undifferentiated carcinoma of the nasopharynx. The patient was treated with chemotherapy alone, but he died after the third cycle...
December 1, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27905167/preoperative-surgical-simulation-and-validation-of-the-line-of-resection-in-anterolateral-craniofacial-resection-of-advanced-sinonasal-sinus-carcinoma
#6
Naoki Nishio, Masazumi Fujii, Yuichiro Hayashi, Mariko Hiramatsu, Takashi Maruo, Kenichiro Iwami, Yuzuru Kamei, Shunjiro Yagi, Keisuke Takanari, Yasushi Fujimoto
BACKGROUND: The purpose of this study was to assess the usefulness and accuracy of preoperative 3D virtual simulation of anterolateral craniofacial resection in cases of advanced sinonasal sinus carcinoma. METHODS: Seven patients with advanced (T4 classification) sinonasal sinus carcinoma who underwent anterolateral craniofacial resection in our hospital between 2011 and 2013 were included in this study. Postsimulation CT images were fused with postoperative CT images and differences between the planned and actual osteotomy were measured in 3 regions of the skull base...
December 1, 2016: Head & Neck
https://www.readbyqxmd.com/read/27901492/genomic-and-transcriptomic-characterization-of-skull-base-chordoma
#7
Jason K Sa, In-Hee Lee, Sang Duk Hong, Doo-Sik Kong, Do-Hyun Nam
Skull base chordoma is a primary rare malignant bone-origin tumor showing relatively slow growth pattern and locally destructive lesions, which can only be characterized by histologic components. There is no available prognostic or therapeutic biomarker to predict clinical outcome or treatment response and the molecular mechanisms underlying chordoma development still remain unexplored. Therefore, we sought out to identify novel somatic variations that are associated with chordoma progression and potentially employed as therapeutic targets...
November 25, 2016: Oncotarget
https://www.readbyqxmd.com/read/27901326/tuberculuma-sellae-meningiomas-a-systematic-review-of-transcranial-approaches-in-the-endoscopic-era
#8
Mazda Turel, Georgios Tsermoulas, Abdulmounem Yasssin-Kassab, Deven Reddy, Hugo Andrade-Barazarte, Lior Gonen, Gelareh Zadeh, Fred Gentili
INTRODUCTION: With the advent of skull base endoscopy, tuberculum sellae meningiomas (TSMs) are currently operated both from the traditional transcranial (TC) route as well as the extended endonasal endoscopic trasnssphenoidal approach (EETS). The aim of this study was to conduct a systematic review of TSMs excised via the TC route in the modern era when the EETS excision is gaining popularity. EVIDENCE ACQUISITION: We performed a systematic review in the medical literature following the PRISMA guidelines...
November 30, 2016: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/27900036/management-of-pediatric-head-and-neck-rhabdomyosarcoma-a-case-series-of-36-patients
#9
Joanna Radzikowska, Wojciech Kukwa, Andrzej Kukwa, Anna M Czarnecka, Maciej Kawecki, Fei Lian, Cezary Szczylik, Antoni Krzeski
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in the pediatric population. In 35% of cases, RMS develops in the head and neck (H&N) region, and only combined therapy is recognized as a curative treatment. However, recent advances in skull base and reconstructive surgery, along with microsurgery and endoscopic surgery, have strengthened the role of surgery as an important part of RMS treatment. In the present study, 36 pediatric RMS cases (24 males and 12 females) were analyzed after surgical treatment...
November 2016: Oncology Letters
https://www.readbyqxmd.com/read/27898607/effects-of-intratympanic-dexamethasone-on-high-dose-radiation-ototoxicity-in-vivo
#10
Christine T Dinh, Si Chen, John Dinh, Stefania Goncalves, Esperanza Bas, Kyle Padgett, Perry Johnson, Nagy Elsayyad, Fred Telischi, Thomas Van De Water
BACKGROUND: Stereotactic radiosurgery for lateral skull base tumors can cause hearing loss when the cochleae are exposed to high doses of single-fraction radiation. Currently, there are no known nondosimetric preventative treatments for radiation-induced ototoxicity. HYPOTHESIS: Intratympanic (IT) dexamethasone (DXM), a synthetic steroid, protects against radiation-induced auditory hair cell (HC) and hearing losses in rats in vivo. METHODS: Seven rats received radiation (12 Gy) to both cochleae...
November 24, 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27895493/ct-diagnosed-severe-skull-base-bone-destruction-predicts-distant-bone-metastasis-in-early-n-stage-nasopharyngeal-carcinoma
#11
Wei Yi, Zhi-Gang Liu, Xian Li, Jiao Tang, Chang-Bin Jiang, Jing-Ye Hu, Zi-Wei Tu, Hui Wang, Dao-Li Niu, Yun-Fei Xia
Bone metastasis is the most frequent type of distant metastasis in nasopharyngeal carcinoma (NPC). In this study, we investigated the correlation between the skull base bone destruction and the distant bone metastasis in patients with NPC. A total of 449 cases with NPC who were diagnosed and had definitive radiotherapy from 2001 to 2006 were enrolled in this study. The skull base bone destruction was diagnosed by computed tomography (CT) in all cases, and 191 patients also underwent magnetic resonance imaging scan...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/27891396/endoscopic-excision-of-symptomatic-simple-bone-cyst-at-skull-base
#12
Prashant Gunawat, Salman Tehran Shaikh, Vikram Karmarkar, Chandrashekhar Deopujari, Nishit Shah
Seizure is a classical feature of intra axial brain parenchymal lesion. Simple bone cyst is an unusual bony pathology at skull base presenting with unexpected symptoms of complex partial seizures. Skull base neuro-endoscopy has managed such lesions more effectively with reduced post-operative morbidity as compared to transcranial approach. This case report discusses a 20-year-old male who presented with 3 episodes of seizure over a time period of 10 months. MRI brain revealed T1 hypo and T2 hyper intense cystic lesion in middle cranial fossa with no enhancement on contrast administration...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27890191/skull-base-imaging-in-the-era-of-minimal-access-surgery
#13
EDITORIAL
Nafi Aygun
No abstract text is available yet for this article.
January 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/27890190/imaging-of-the-sella-and-parasellar-region
#14
REVIEW
John L Go, Anandh G Rajamohan
The sella and parasellar region, found between the anterior and central skull base, represents the central aspect of the skull base. Given the location of the pituitary gland in this location, small lesions in this location may have major physiologic effects on the human body. This article reviews the anatomy, development, and pathologic processes that may involve this region.
January 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/27890189/diplopia-what-to-double-check-in-radiographic-imaging-of-double-vision
#15
REVIEW
Claudia F E Kirsch, Karen Black
When patients see double with both eyes open, known as "binocular diplopia," this may be a harbinger of underlying life-threatening causes. This article presents pertinent anatomy, critical abnormality, and radiographic features that should be double checked for in diplopia. Key areas requiring a double check using the acronym VISION include Vascular, Infectious and Inflammatory, the Scalp for giant cell arteritis, Sphenoid and Skull base in trauma, Increased intracranial pressure (pseudotumor cerebri), Onset of new headaches or psychosis, and Neoplasm...
January 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/27890188/imaging-of-the-central-skull-base
#16
REVIEW
Lindsey M Conley, C Douglas Phillips
The skull base is a complex bony and soft tissue interface that is divided anatomically into compartments. This article will focus specifically on the central skull base, which has a complex embryologic development and anatomy. Multiple entities from notochord remnants, neoplasm, infection, and other abnormalities may occur, and imaging is critical for depicting skull base pathology.
January 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/27890187/imaging-of-paranasal-sinuses-and-anterior-skull-base-and-relevant-anatomic-variations
#17
REVIEW
Estushi Iida, Yoshimi Anzai
This article reviews the normal anatomy and variants of the anterior skull base and sinonasal cavities that are relevant to endoscopic sinus and skull base surgery. Radiologists should be aware of sinonasal anatomy that can be impediments to surgical access and increase risk of vascular or cranial nerve injury during surgery. Imaging features of the paranasal sinuses and anterior skull base pathologies are also discussed.
January 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/27890186/advanced-imaging-techniques-of-the-skull-base
#18
REVIEW
Elliot Dickerson, Ashok Srinivasan
Although conventional imaging can depict the anatomy of the head and neck with exquisite detail, it often falls short in its ability to characterize tissue physiology and abnormality; this is especially seen in the posttherapy setting where benign posttreatment changes and recurrent tumors can show intense postcontrast enhancement and similar features on conventional imaging. Advanced imaging can evaluate tissue physiology and, along with conventional imaging, provide a more accurate assessment of the skull base...
January 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/27890185/high-resolution-three-dimensional-mr-imaging-of-the-skull-base-compartments-boundaries-and-critical-structures
#19
REVIEW
Ari Meir Blitz, Nafi Aygun, Daniel A Herzka, Masaru Ishii, Gary L Gallia
High-resolution 3D MRI of the skull base allows for a more detailed and accurate assessment of normal anatomic structures as well as the location and extent of skull base pathologies than has previously been possible. This article describes the techniques employed for high-resolution skull base MRI including pre- and post-contrast constructive interference in the steady state (CISS) imaging and their utility for evaluation of the many small structures of the skull base, focusing on those regions and concepts most pertinent to localization of cranial nerve palsies and in providing pre-operative guidance and post-operative assessment...
January 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/27890183/imaging-evaluation-and-treatment-of-vascular-lesions-at-the-skull-base
#20
REVIEW
Gaurav Jindal, Timothy Miller, Prashant Raghavan, Dheeraj Gandhi
A wide range of congenital and acquired vascular entities may occur in the skull base. Although some are diagnosed incidentally and merit no treatment, others may require surgical or image-guided endovascular or percutaneous approaches for management. The complex anatomy of the skull base can make diagnosis challenging. A combination of computed tomography scans and MR imaging, and catheter angiography may be required for diagnosis and mapping. Endovascular treatment plays an important part in many of the acquired vascular lesions, such as vascular neoplasms and traumatic dissections/aneurysms...
January 2017: Radiologic Clinics of North America
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