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https://www.readbyqxmd.com/read/29779184/limbic-system-structure-volumes-and-associated-neurocognitive-functioning-in-former-nfl-players
#1
Christian Lepage, Marc Muehlmann, Yorghos Tripodis, Jakob Hufschmidt, Julie Stamm, Katie Green, Pawel Wrobel, Vivian Schultz, Isabelle Weir, Michael L Alosco, Christine M Baugh, Nathan G Fritts, Brett M Martin, Christine Chaisson, Michael J Coleman, Alexander P Lin, Ofer Pasternak, Nikos Makris, Robert A Stern, Martha E Shenton, Inga K Koerte
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with exposure to repetitive head impacts. CTE has been linked to disruptions in cognition, mood, and behavior. Unfortunately, the diagnosis of CTE can only be made post-mortem. Neuropathological evidence suggests limbic structures may provide an opportunity to characterize CTE in the living. Using 3 T magnetic resonance imaging, we compared select limbic brain regional volumes - the amygdala, hippocampus, and cingulate gyrus - between symptomatic former National Football League (NFL) players (n = 86) and controls (n = 22)...
May 19, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29779059/youth-responses-to-school-shootings-a-review
#2
REVIEW
Áine Travers, Tracey McDonagh, Ask Elklit
PURPOSE OF REVIEW: This paper aims to synthesize research relating to youth responses to school shootings between 2014 and 2017. The main questions it addresses are how such events impact young people psychologically, and what risk or protective factors may contribute to different trajectories of recovery? RECENT FINDINGS: Recent research suggests that most young people exposed to school shootings demonstrate resilience, exhibiting no long-term dysfunction. However, a minority will experience severe and chronic symptoms...
May 19, 2018: Current Psychiatry Reports
https://www.readbyqxmd.com/read/29779039/differences-between-traumatic-and-non-traumatic-causes-of-acl-revision-surgery
#3
Vera Jaecker, Tabea Zapf, Jan-Hendrik Naendrup, Ajay C Kanakamedala, Thomas Pfeiffer, Sven Shafizadeh
PURPOSE: The purpose of this study was to evaluate and classify causes for anterior cruciate ligament (ACL) reconstruction failure. It was hypothesized that specific technical and biological reconstruction aspects would differ when comparing traumatic and non-traumatic ACL reconstruction failures. MATERIALS AND METHODS: One hundred and forty-seven consecutive patients who experienced ACL reconstruction failure and underwent revision between 2009 and 2014 were analyzed...
May 19, 2018: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29778829/a-qualitative-investigation-of-the-attitudes-and-beliefs-about-physical-activity-and-post-traumatic-osteoarthritis-in-young-adults-3-10-years-after-an-intra-articular-knee-injury
#4
Allison M Ezzat, Mariana Brussoni, Jackie L Whittaker, Carolyn A Emery
OBJECTIVE: To understand the influence of the injury experience on current attitudes and beliefs about physical activity (PA) and the development of post-traumatic osteoarthritis (PTOA) in youth and young adults 3-10 years after a sport-related knee injury. DESIGN: Qualitative study. SETTING: University Sports Medical/Research Center. PARTICIPANTS: 20 young adults 3-10 years subsequent to intra-articular knee injury...
May 4, 2018: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29778611/traumatic-aorto-cisterna-chlyi-fistula-with-treatment-of-aortic-pseudoaneurysm-with-ct-guided-thrombin-injection
#5
Brian M Freeman, Benjamin C Powell, A Michael Devane, Allyson L Hale, Sagar S Gandhi
INTRODUCTION: Only 3 cases of aorto-cisterna chyli fistula have been described in the literature but none with a resulting pseudoaneurysm (PSA). CASE REPORT: A 68-year-old man presented following a motor vehicle collision. Imaging revealed a retroperitoneal hematoma with enhancement of the cisterna chyli, representing aortic to cisterna chyli fistula. Three days later CTA showed resolution of the fistula, but revealed a PSA. The patient underwent arteriography that confirmed the PSA, and then a CT-guided thrombin injection was performed...
May 17, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29778418/correlation-between-translational-and-rotational-kinematic-abnormalities-and-osteoarthritis-like-damage-in-two-in-vivo-sheep-injury-models
#6
Mehdi Shekarforoush, Jillian E Beveridge, David A Hart, Cyril B Frank, Nigel G Shrive
The relations between kinematic abnormalities and post traumatic osteoarthritis have not yet been clearly elucidated. This study was conducted to determine the finite helical axes parameters and the tibiofemoral translation vector in the knee joints of two surgically induced injury sheep models: anterior cruciate ligament and medial collateral ligament transection (ACL/MCL Tx) (n = 5) and lateral meniscectomy (n = 5). We hypothesized that morphological damage in the experimental joints would be correlated to alterations in these kinematic variables...
May 16, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29778303/the-physiopathologic-interplay-between-stem-cells-and-tissue-niche-in-muscle-regeneration-and-the-role-of-il-6-on-muscle-homeostasis-and-diseases
#7
Laura Forcina, Carmen Miano, Antonio Musarò
Skeletal muscle is a complex, dynamic tissue characterized by an elevated plasticity. Although the adult muscle is mainly composed of multinucleated fibers with post mitotic nuclei, it retains a remarkable ability to regenerate in response to traumatic events. The regenerative potential of the adult skeletal muscle relies in the activity of satellite cells, mononucleated cells residing within the muscle in intimate association with myofibers. Satellite cells normally remain quiescent in their sublaminar position, sporadically entering the cell cycle to guarantee an efficient cellular turnover, by fusing with pre-existing myofibers, and to maintain the stem cell pool...
May 16, 2018: Cytokine & Growth Factor Reviews
https://www.readbyqxmd.com/read/29778284/-clinical-and-epidemiological-profile-of-pediatric-uveitis-course-of-inflammatory-uveitis-treated-with-anti-tnf-alpha
#8
D Osswald, A C Rameau, C Speeg-Schatz, J Terzic, A Sauer
INTRODUCTION: Uveitis is the leading cause of acquired childhood blindness with a prevalence of 30 cases per 100,000 inhabitants. There are multiple causes ; nevertheless, there is no standardized etiological assessment. The goal of our study is to define an epidemiological and clinical profile of uveitis diagnosed in a university hospital and their course when treated with anti-tumor necrosis factor (TNF) α. PATIENTS AND METHODS: All cases of uveitis under 18 years old, from 1994 to 2016, were included...
May 16, 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29778092/magnetic-resonance-imaging-for-detecting-root-avulsions-in-traumatic-adult-brachial-plexus-injuries-protocol-for-a-systematic-review-of-diagnostic-accuracy
#9
Ryckie G Wade, Yemisi Takwoingi, Justin C R Wormald, John P Ridgway, Steven Tanner, James J Rankine, Grainne Bourke
BACKGROUND: Adult brachial plexus injuries (BPI) are becoming more common. The reconstruction and prognosis of pre-ganglionic injuries (root avulsions) are different to other types of BPI injury. Preoperative magnetic resonance imaging (MRI) is being used to identify root avulsions, but the evidence from studies of its diagnostic accuracy are conflicting. Therefore, a systematic review is needed to address uncertainty about the accuracy of MRI and to guide future research. METHODS: We will conduct a systematic search of electronic databases alongside reference tracking...
May 19, 2018: Systematic Reviews
https://www.readbyqxmd.com/read/29778065/reliability-of-the-sub-components-of-the-instrumented-timed-up-and-go-test-in-ambulatory-children-with-traumatic-brain-injury-and-typically-developed-controls
#10
Mark A Newman, Mark A Hirsch, Richard D Peindl, Nahir A Habet, Tobias J Tsai, Michael S Runyon, Toan Huynh, Nigel Zheng
BACKGROUND: Studies have evaluated the test-re-test reliability of subcomponents of the timed up and-go test in adults by using body-worn inertial sensors. However, studies in children have not been reported in the literature. RESEARCH QUESTION: To evaluate the within-session reliability of subcomponents of a newly developed electronically augmented timed 'upand-go' test (EATUG) in ambulatory children with traumatic brain injury (TBI) and children with typical development (TD)...
May 16, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29778052/self-reported-nonsuicidal-self-injury-nssi-and-sex-as-self-injury-sasi-relationship-to-abuse-risk-behaviors-trauma-symptoms-self-esteem-and-attachment
#11
Maria Zetterqvist, Carl Göran Svedin, Cecilia Fredlund, Gisela Priebe, Marie Wadsby, Linda S Jonsson
This study focuses on a conceptually unexplored behavior among adolescents who report deliberately using sex as a means of self-injury. In a large high school-based sample (n = 5743), adolescents who engaged in sex as self-injury (SASI, n = 43) were compared to adolescents who reported direct nonsuicidal self-injury (NSSI, n = 933) and those who reported both NSSI and SASI (n = 82). Results showed that significantly more adolescents with SASI had experience of penetrating sexual abuse, as well as more sexual partners compared to those with NSSI...
May 7, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29778050/the-association-between-ptsd-and-facial-affect-recognition
#12
Christian L Williams, Melissa E Milanak, Matt R Judah, Howard Berenbaum
The major aims of this study were to examine how, if at all, having higher levels of PTSD would be associated with performance on a facial affect recognition task in which facial expressions of emotion are superimposed on emotionally valenced, non-face images. College students with trauma histories (N = 90) completed a facial affect recognition task as well as measures of exposure to traumatic events, and PTSD symptoms. When the face and context matched, participants with higher levels of PTSD were significantly more accurate...
May 5, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29778039/identifying-the-trauma-recovery-needs-of-maltreated-children-an-examination-of-child-welfare-workers-effectiveness-in-screening-for-traumatic-stress
#13
Adrienne Whitt-Woosley, Ginny Sprang, David G Royse
Children in the child welfare system comprise a group characterized by exposure to trauma via experiences of maltreatment, under circumstances presenting multiple risk factors for traumatic stress. High rates of posttraumatic stress have been observed in this population. However, there is currently no standard for the universal screening of children in child welfare for trauma exposure and traumatic stress. This study examined the trauma experiences of a sample of maltreated children and whether their child welfare workers were effective screeners of traumatic stress symptoms...
May 16, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29777982/documentation-and-analysis-of-traumatic-injuries-in-clinical-forensic-medicine-involving-structured-light-three-dimensional-surface-scanning-versus-photography
#14
Awatif Shamata, Tim Thompson
Non-contact three-dimensional (3D) surface scanning has been applied in forensic medicine and has been shown to mitigate shortcoming of traditional documentation methods. The aim of this paper is to assess the efficiency of structured light 3D surface scanning in recording traumatic injuries of live cases in clinical forensic medicine. The work was conducted in Medico-Legal Centre in Benghazi, Libya. A structured light 3D surface scanner and ordinary digital camera with close-up lens were used to record the injuries and to have 3D and two-dimensional (2D) documents of the same traumas...
May 10, 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29777967/rates-and-correlates-of-disordered-eating-among-women-veterans-in-primary-care
#15
Laura J Buchholz, Paul R King, Laura O Wray
Rates of disordered eating may be higher among women veterans than civilians, and are associated with co-occurring mental health (MH) conditions, such as depression, post-traumatic stress disorder (PTSD), and alcohol misuse. Although evidence suggests that these conditions are common in primary care settings, limited research has examined symptoms of disordered eating among women veterans in primary care. This study used a cross-sectional design to examine rates and MH correlates of disordered eating among women veterans treated in a primary care setting...
May 16, 2018: Eating Behaviors
https://www.readbyqxmd.com/read/29777892/surgically-treated-de-novo-cervico-medullary-arachnoid-cyst-in-a-symptomatic-adult-patient
#16
William Clifton, Gazanfar Rahmathulla, Kourosh Tavanaiepour, Dunbar Alcindor, George Jakubek, Daryoush Tavanaiepour
Arachnoid cysts are a relatively common finding in adult patients, especially with the advent of advanced imaging techniques. The overall incidence ranges from 1-2%, and the majority are clinically silent1,2 . Arachnoid cysts are postulated to arise by congenital anomalies or trauma1 . De novo formation of arachnoid cysts has been reported, but is exceptionally rare and mostly found in the pediatric population after head trauma3-5 . There have only been two reported cases of symptomatic de novo arachnoid cyst formation in adult patients to date, both with histories of head trauma6,7 ...
May 16, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29777885/posttraumatic-cerebrospinal-fluid-leak-associated-with-an-upper-cervical-meningeal-diverticulum
#17
Noriya Enomoto, Hideo Mure, Toshiyuki Okazaki, Mai Azumi, Shinya Okita, Shinji Nagahiro, Yasushi Takagi
Spontaneous intracranial hypotension (SIH) has been increasingly recognized as a phenomenon caused by cerebrospinal fluid (CSF) leaks; however, its pathogenesis is still unclear. Here, we report two cases of SIH as a result of CSF leak from a meningeal diverticulum at the C2 nerve root sleeve. The first case is that of a 46-year-old man who had suffered from orthostatic headache after a bicycle accident at age 45. Computed tomography (CT) myelography revealed CSF leaks at the C1/2 level. He underwent epidural blood patch (EBP) therapy, but it was unsuccessful...
May 16, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29777884/neurosurgical-management-of-self-inflicted-cranial-crossbow-injury
#18
Charles G Kulwin, Andrew DeNardo, Saad Khairi, Troy Payner
BACKGROUND: While gun-related penetrating traumatic brain injuries make up the majority of cranial missile injuries, low-velocity penetrating injuries present significant clinical difficulties that cannot necessarily be identically managed. Bow hunting is an increasingly popular pastime, and a crossbow allows a unique mechanism to cause a self-inflicted cranial injury with a large, low-velocity projectile. Historically, arrow removal is described in an operating room setting, which provides limited knowledge of the location of vascular injury in the setting of post-removal hemorrhage, and may represent an inefficient use of operating room availability...
May 16, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29777771/assessing-the-longer-term-effects-of-mild-traumatic-brain-injury-on-self-reported-driving-ability
#19
John Bernstein, Matthew Calamia
BACKGROUND: Mild traumatic brain injury (mTBI) may have long-term cognitive and functional consequences, and recent mTBI is associated with impaired performance on measures related to driving ability. However, it remains unclear whether prior mTBI history is associated with poorer driving performance. OBJECTIVE: To examine the longer-term effects of mTBI on self-reported driving ability. DESIGN: Retrospective, cross-sectional study. SETTING: Online...
May 16, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29777694/gapdh-targeted-therapy-a-new-approach-for-secondary-damage-after-traumatic-brain-injury-on-rats
#20
Vladimir F Lazarev, Elizaveta A Dutysheva, Elena Y Komarova, Elena R Mikhaylova, Irina V Guzhova, Boris A Margulis
Massive neuronal death caused by a neurodegenerative pathology or damage due to ischaemia or traumatic brain injury leads to the appearance of cytosolic proteins in the extracellular space. We found that one of the most abundant cellular polypeptides, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), appearing in the medium of dying cells or body fluids is able to form aggregates that are cytotoxic to adjacent cells. Since we previously showed that the hydrocortisone derivative RX624 can inhibit the ability of GAPDH to transport the enzyme complex with polyglutamine and reduce the cytotoxicity of the complex, we explored the effects of GAPDH on SH-SY5Y neuroblastoma cells...
May 16, 2018: Biochemical and Biophysical Research Communications
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