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https://www.readbyqxmd.com/read/28499796/the-antenatal-urinary-tract-dilation-classification-system-accurately-predicts-severity-of-kidney-and-urinary-tract-abnormalities
#1
C D W Kaspar, M Lo, T E Bunchman, N Xiao
BACKGROUND: Urinary tract dilation (UTD) is a commonly diagnosed prenatal condition; however, it is currently unknown which features lead to benign and resolving or pathologic abnormalities. A consensus UTD classification system (antenatal UTD classification, UTD-A) was created by Nguyen et al. in 2014 [1], but has not yet been validated. OBJECTIVE: To evaluate the ability of the UTD-A system to identify kidney and urinary tract (KUT) abnormalities, assess whether UTD-A can predict severity of KUT conditions, and perform a cost analysis of screening ultrasound (US)...
April 21, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28493533/combination-diagnosis-of-multi-slice-spiral-computed-tomography-and-secretary-phospholipase-a2-iia-for-solitary-pulmonary-nodules
#2
Hongjun Hou, Zushan Xu, Hongsheng Zhang, Yan Xu
INTRODUCTION: This study was aimed to compare the diagnostic value of multi-slice spiral computed tomography (CT) and secretary phospholipase A2-IIa (sPLA2-IIa) in differentiating between malignant and benign solitary pulmonary nodules (SPNs). METHODS: A total of 223 patients with SPNs (91 patients with malignant SPNs and 132 patients with benign SPNs) were included from Weihai Central Hospital during October 2014 to December 2016. SPN diagnosis was confirmed in all patients using needle biopsy, surgery and bronchoscopy...
May 11, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28477165/diagnostic-accuracy-of-surface-coil-mri-in-assessing-cartilaginous-invasion-in-laryngeal-tumours-do-we-need-contrast-agent-administration
#3
Lorenzo Preda, Giorgio Conte, Luke Bonello, Caterina Giannitto, Elena Tagliabue, Sara Raimondi, Mohssen Ansarin, Luigi De Benedetto, Augusto Cattaneo, Fausto Maffini, Massimo Bellomi
OBJECTIVES: To assess the diagnostic accuracy of MRI performed using surface coils, with and without contrast medium, in predicting thyroid and cricoid cartilage infiltration in laryngeal tumours, and to investigate whether the radiologist's experience influences diagnostic accuracy. METHODS: We retrospectively enrolled patients with biopsy-proven laryngeal cancer who had undergone preoperative staging MRI and open surgery. Two radiologists with different experience (senior vs...
May 5, 2017: European Radiology
https://www.readbyqxmd.com/read/28474283/hucmncs-protect-vascular-endothelium-and-prevent-isr-after-endovascular-interventional-therapy-for-vascular-diseases-in-t2dm-rabbits
#4
Haixia Ding, Tong Zhang, Yaping Du, Bei Liu, Yueqin Liu, Fujun Wang
The therapeutic effect of transplantation of human umbilical cord blood cell-derived mononuclear cells (HUCMNCs) on treating in-stent restenosis (ISR) after endovascular interventional therapy (EIT) was evaluated in preclinical rabbit model of type 2 diabetes mellitus (T2DM)-related peripheral artery disease (PAD). HUCMNCs were transplanted to T2DM rabbits subjected to femoral artery occlusion surgery and received EIT. Serum concentration of soluble vascular endothelial cadherin (VE-cad) and plasma concentration of lipoprotein-associated phospholipase A2 (Lp-PLA2) were determined with enzyme-linked immunosorbent assay before and after the transplantation...
May 4, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/28460465/functional-characterisation-of-a-novel-ovarian-cancer-cell-line-nuoc-1
#5
Aiste McCormick, Eleanor Earp, Katherine Elliot, Gavin Cuthbert, Rachel O'Donnell, Brian T Wilson, Ruth Sutton, Charlotte Leeson, Huw D Thomas, Helen Blair, Sarah Fordham, John Lunec, James Allan, Richard J Edmondson
BACKGROUND: Cell lines provide a powerful model to study cancer and here we describe a new spontaneously immortalised epithelial ovarian cancer cell line (NUOC-1) derived from the ascites collected at a time of primary debulking surgery for a mixed endometrioid / clear cell / High Grade Serous (HGS) histology. RESULTS: This spontaneously immortalised cell line was found to maintain morphology and epithelial markers throughout long-term culture. NUOC-1 cells grow as an adherent monolayer with a doubling time of 58 hours...
April 18, 2017: Oncotarget
https://www.readbyqxmd.com/read/28446184/results-of-167-consecutive-cases-of-acetabular-fractures-using-the-kocher-langenbeck-approach-a-case-series
#6
Lukas L Negrin, David Seligson
BACKGROUND: Acetabular fractures are quite challenging injuries for the orthopedic surgeon because of their low incidence and their deep and complex anatomy. The objective of this study was to evaluate surgeon-independent parameters that might influence radiographic outcome and early complication rates of high-energy acetabular fractures treated by open reduction and internal fixation via the Kocher-Langenbeck approach, the golden standard for posterior access. METHODS: One hundred sixty-seven consecutive patients (111 males and 56 females) with a mean age of 41...
April 26, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28433374/peritoneal-fluid-cytokines-related-to-endometriosis-in-patients-evaluated-for-infertility
#7
Hilde Jørgensen, Abby S Hill, Michael T Beste, Manu P Kumar, Evan Chiswick, Peter Fedorcsak, Keith B Isaacson, Douglas A Lauffenburger, Linda G Griffith, Erik Qvigstad
OBJECTIVE: Our aim was to characterize peritoneal cytokine profiles in patients with infertility, with and without endometriosis, to illuminate potential differences in immune profiles that may reflect mechanistic differences between these two patient populations. DESIGN: Cross-sectional study. SETTING: University hospital and research center. PATIENT(S): Women undergoing laparoscopy for infertility investigation (n = 107)...
April 19, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28407019/comparison-between-titanium-mesh-and-autogenous-iliac-bone-graft-to-restore-vertebral-height-through-posterior-approach-for-the-treatment-of-thoracic-and-lumbar-spinal-tuberculosis
#8
COMPARATIVE STUDY
Yongjian Gao, Yunsheng Ou, Qianxing Deng, Bin He, Xing Du, Jianxiao Li
OBJECT: To compare the clinical efficacy of titanium mesh cages and autogenous iliac bone graft to restore vertebral height through posterior approach in patients with thoracic and lumbar spinal tuberculosis. METHOD: 59 patients with spinal tuberculosis underwent interbody fusion and internal fixation through posterior approach in our department from January 2011 to December 2013. In group A, 34 patients obtained titanium mesh for the reconstruction of vertebral height, among them 25 patients (group A1) suffered from single-segment spinal tuberculosis, and 9 patients, (group A2) had multi-segment spinal tuberculosis...
2017: PloS One
https://www.readbyqxmd.com/read/28399882/liver-necrosis-shortly-after-pancreaticoduodenectomy-with-resection-of-the-replaced-left-hepatic-artery
#9
Michihiro Yamamoto, Masazumi Zaima, Hidekazu Yamamoto, Hideki Harada, Junichiro Kawamura, Masahiro Yamada, Tekefumi Yazawa, Junya Kawasoe
BACKGROUND: Surgeons, in general, underestimate the replaced left hepatic artery (rLHA) that arises from the left gastric artery (LGA), compared with the replaced right hepatic artery (rRHA), especially in standard gastric cancer surgery. During pancreaticoduodenectomy (PD), preservation of the rRHA arising from the superior mesenteric artery (SMA) is widely accepted to prevent critical postoperative complications, such as liver necrosis, bile duct ischemia, and biliary anastomotic leakage...
April 11, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28387197/primary-hemiarthroplasty-for-treatment-of-unstable-pertrochanteric-femoral-fractures-ao-ota-type-31-a2-3-in-elderly-osteoporotic-patients
#10
Skender Ukaj, Bahri Gjyshinca, Vlora Podvorica, Fatime Ukaj, Granit Molliqaj, Arben Boshnjaku, Axel Gamulin
INTRODUCTION: The aim of this study was to prospectively analyze the role of primary hemiarthroplasty in unstable osteoporotic pertrochanteric fractures (AO/OTA Type 31 A2.3), with emphasis given to postoperative Functional Independent Measure (FIM) and Harris Hip Score (HHS). METHODS: Fifty-six consecutive patients (average age 78.25 ± 5.45), out of which 24 males (79.29 ± 4.99) and 32 females (77.47 ± 5.72), with unstable pertrochanteric femoral fractures, operated with primary hemiarthroplasty procedure from 2012 to 2014 were included in this prospective study with a follow-up of two years...
2017: SICOT-J
https://www.readbyqxmd.com/read/28372453/coloduodenal-and-enterocutaneous-fistula-in-twins-with-crohn%C3%A2-s-disease
#11
Maíia Pilar Ballester, David Martí, Marta Maia Boscá Watts, José Martín Arévalo, Miguel Mínguez
We present the case of a pair of 45-year-old monozygotic twins (A and B) diagnosed with Crohn's disease (CD) at age 20 (A) and 22 (B) with similar presenting symptoms: diarrhea, fever and weight loss. Both of them had duodenal and ileocolonic disease (A2, L3+L4 according to Montreal classification); twin B also presented jejunal involvement and perianal disease (B1p). They received treatment with antibiotics, corticosteroids, 5-ASA, azathioprine and anti-TNF with a poor control of activity. They both developed a coloduodenal fistula that required surgery...
April 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28365357/chronic-kidney-disease-is-more-common-in-locally-advanced-renal-cell-carcinoma
#12
Sumi Dey, Zachary Hamilton, Sabrina L Noyes, Conrad M Tobert, Jacob Keeley, Ithaar H Derweesh, Brian R Lane
OBJECTIVE: To retrospectively evaluate clinical predictors of CKD in RCC patients to identify associations between patient- and tumor-specific factors with poorer renal function. Chronic kidney disease (CKD) and renal cell carcinoma (RCC) are inter-related, with 26-44% of RCC patients having concomitant CKD at diagnosis. METHODS: Institutional registries from SH and UCSD were queried for preoperative GFR and proteinuria status prior to radical or partial nephrectomy...
March 29, 2017: Urology
https://www.readbyqxmd.com/read/28359639/lateral-para-olecranon-approach-for-the-treatment-of-distal-humeral-fracture
#13
Takuji Iwamoto, Taku Suzuki, Noboru Matsumura, Masaya Nakamura, Morio Matsumoto, Kazuki Sato
PURPOSE: To assess the outcomes of the lateral para-olecranon triceps-splitting approach for the treatment of distal humeral fracture. METHODS: Ten patients (3 males, 7 females) with a mean age of 59 years were retrospectively reviewed. There were 2 A2, 3 C1, and 5 C2 fractures according to the AO/ASIF classification. Types B3 and C3 fractures were excluded from this study because the olecranon osteotomy approach was indicated to visualize the anterior fragment...
May 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28350758/effects-of-ultralow-topic-estriol-dose-on-vaginal-health-and-quality-of-life-in-postmenopausal-women-who-underwent-surgical-treatment-for-pelvic-organ-prolapse
#14
Salvatore Caruso, Stefano Cianci, Salvatore Giovanni Vitale, Maria Grazia Matarazzo, Francesca Flavia Amore, Antonio Cianci
OBJECTIVE: To evaluate the efficacy of low concentrations of vaginal estriol gel in postmenopausal women with pelvic static disorders before and after vaginal surgical treatment, assessing vaginal health, sexual function, and quality of life (QoL). METHODS: Women affected by genital prolapse were enrolled. Vaginal health, QoL, and sexual function were investigated at baseline (T0), before surgery (T1), and 13 weeks after surgery (T2). At baseline, participants were randomized 1:1...
March 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28347710/prostanoids-in-the-pathophysiology-of-human-coronary-artery
#15
REVIEW
Gulsev Ozen, Xavier Norel
Coronary artery disease is one of the leading causes of death in wordwide. There is growing evidence that prostanoids are involved in the physiology and pathophysiology of the human coronary artery by controlling vascular tone, remodelling of the vascular wall or angiogenesis. In this review, the production of prostanoids and the expression of prostanoid receptors in human coronary artery in health or disease are described. In addition, the interactions between sex hormones and prostanoids, their participations in the development of coronary artery diseases have been addressed...
March 24, 2017: Prostaglandins & Other Lipid Mediators
https://www.readbyqxmd.com/read/28286182/crotalus-helleri-venom-preconditioning-reduces-postoperative-cerebral-edema-and-improves-neurological-outcomes-after-surgical-brain-injury
#16
Cherine H Kim, Devin W McBride, Prativa Sherchan, Carl E Person, Eric C K Gren, Wayne Kelln, Tim Lekic, William K Hayes, Jiping Tang, John H Zhang
INTRODUCTION: Postoperative cerebral edema is a devastating complication in neurosurgical patients. Loss of blood-brain barrier integrity has been shown to lead to the development of brain edema following neurosurgical procedures. The aim of this study was to evaluate preconditioning with Crotalus helleri venom (Cv-PC) as a potential preventive therapy for reducing postoperative brain edema in the rodent SBI model. C. helleri venom is known to contain phospholipase A2 (PLA2), an enzyme upstream to cyclooxygenase-2 (COX-2) in the inflammatory cascade, acts to increase the production of inflammatory mediators, such as prostaglandins...
March 9, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/28274519/regional-heterogeneity-in-the-mitral-valve%C3%A2-apparatus-in-patients-with-ischemic%C3%A2-mitral-regurgitation
#17
Feroze Mahmood, Ziyad O Knio, Lu Yeh, Rabia Amir, Robina Matyal, Azad Mashari, Robert C Gorman, Joseph H Gorman, Kamal R Khabbaz
BACKGROUND: Apical displacement of the coaptation point of the mitral valve (MV) in response to ischemic mitral regurgitation (IMR) represents remodeling of the MV apparatus. Whereas it implies chronicity, it lacks specificity in discriminating normal from a significantly remodeled MV apparatus. Regional aspects of MV remodeling have shown superior value over global remodeling in predicting recurrence after MV repair for IMR. Quite possibly, presence of specific regional changes in MV geometry that are unique to chronic IMR patients could also be used to diagnose the presence and track progression of remodeling...
April 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28273677/-first-results-with-a-resorbable-mgyrezr-compression-screw-in-unstable-scaphoid-fractures-show-extensive-bone-cysts
#18
Reinhard Meier, Martin Panzica
Osteosynthesis with headless compression screws is an established treatment option for unstable scaphoid fractures. Common implants are made of titanium alloy or steel and usually remain in place. Due to implant density and ferromagnetic properties, artefacts are common in postoperative imaging procedures, e.g. MRI. Now resorbable implants made of magnesium alloy (MgYREZr) have become available. They have biomechanical properties equivalent to human bone and may be used as an alternative to the nonresorbable screw systems...
February 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/28241726/-bone-cement-dry-prosthetic-with-internal-fixation-treat-senile-osteoporotic-femoral-fractures
#19
Y Jiang, X X Rong, P Chen, Y J Xu, G X Zhu
Objective: To explore the treatment of senile osteoporotic femoral fractures after using internal fixation of bone cement dry prosthetic. Methods: Twelve patients aged from 74 to 94 years with mean age of (84.0±2.5) years with internal fixation of bone cement dry prosthetic surgery who were treated at Department of Orthopaedics in Nanjing Medical University Affiliated Wuxi Second Hospital between May 2013 and May 2015 were retrospectively analyzed. There were 8 male and 4 female, 10 cases of tumble and 2 cases of traffic injury...
March 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28222145/cataract-surgery-causes-biomechanical-alterations-to-the-eye-detectable-by-corvis-st-tonometry
#20
Yoshitake Kato, Shunsuke Nakakura, Ryo Asaoka, Kanae Matsuya, Yuki Fujio, Yoshiaki Kiuchi
PURPOSE: Modern cataract surgery is generally considered to bring about modest and sustained intraocular pressure (IOP) reduction. However, the pathophysiological mechanism for this remains unclear. Moreover, a change in ocular biomechanical properties after surgery can affect the measurement of IOP. The aim of the study is to investigate ocular biomechanics, before and following cataract surgery, using Corvis ST tonometry (CST). PATIENTS AND METHODS: Fifty-nine eyes of 59 patients with cataract were analyzed...
2017: PloS One
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