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https://www.readbyqxmd.com/read/29353338/the-use-of-infant-confinement-equipment-in-community-based-child-care-centers-an-analysis-of-centers-participating-in-a-statewide-quality-rating-and-improvement-system
#1
Rena A Hallam, Kaitlin Bargreen, Hillary N Fouts, Laura Lessard, Christine Skrobot
Objectives Although infants increasingly spend time in community-based child care centers, little attention has been paid to their physical activity experiences while in group care. In particular, the use of devices to restrict infant mobility, such as bouncy seats, high chairs, cribs, and stationary activity centers, has received little attention in the physical activity literature. The current study examines the presence and use of these confinement devices in infant classrooms. Methods A secondary analysis of observational data in child care centers participating in Delaware's Quality Rating and Improvement System was conducted...
January 20, 2018: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29353331/construction-of-a-plasmid-vector-containing-epidermal-growth-factor-receptor-and-c-jun-shrna
#2
Hong Xiao, Ruinian Yang, Fang Yang, Yanan Zhao, Yin Liu
The objective of this study was to construct a plasmid vector for EGFR-hm-1 and C-Junh-825 small interfering RNA (siRNA). EGFR-hm-1 and C-Jun-hm-825 oligonucleotide fragments were synthesized and short hairpin RNA (shRNA) were amplified by PCR. Plasmids were isolated from E. coli TOP10 bacterium by restriction enzyme digestion using pst1 and BamH1 and oligonucleotide fragments were cloned into the pSilencer plasmid containing the U6 promoter. Recombinant clones were generated by transforming JM109 competent cells with plasmid vectors containing shRNA molecules...
January 20, 2018: Archives of Dermatological Research
https://www.readbyqxmd.com/read/29353312/child-labour-and-health-a-systematic-review
#3
REVIEW
Brice Lionel Batomen Kuimi, Oduro Oppong-Nkrumah, Jay Kaufman, Jose Ignacio Nazif-Munoz, Arijit Nandi
OBJECTIVES: This study aimed to synthesise the available knowledge, identify unexplored areas and discuss general limits of the published evidence. We focused on outcomes commonly hypothesised to be affected by child labour: nutritional status, harmful exposures and injuries. METHODS: Four electronic databases (EMBASE, MEDLINE, Scopus, ISI Web of Science) were searched in November 2017. All articles published since 1996, without restrictions on language, were considered for inclusion...
January 20, 2018: International Journal of Public Health
https://www.readbyqxmd.com/read/29353271/erythrocytes-and-skeletal-muscle-unsaturated-and-omega-6-fatty-acids-are-positively-correlated-after-caloric-restriction-and-exercise
#4
Miquel Martorell, Victoria Pons, Joan Carles Domingo, Xavier Capó, Antoni Sureda, Franchek Drobnic, Josep-Antoni Tur, Antoni Pons
BACKGROUND: Nutritional intervention studies with fatty acid (FA) supplements assess the efficacy of the intervention by measuring the changes in erythrocyte membrane lipid profiles reflected in tissue composition changes. The aim was to determine the effects of caloric restriction (CR) on erythrocytes lipid composition and to compare and correlate these changes with skeletal muscle acid profiles after CR. METHODS: Erythrocytes were obtained from 11 healthy men before and after 4 weeks of 33% CR in post-exercise conditions; muscle biopsies were obtained from the same athletes after 4 weeks of 33% CR in post-exercise conditions...
January 19, 2018: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/29353247/hydroxychloroquine-induced-restrictive-cardiomyopathy-a-case-report
#5
Muhammad U Dogar, Niel N Shah, Sameera Ishtiaq, Parin N Shah, Pratik Shah, Shawn Mathew, Timothy J Vittorio
No abstract text is available yet for this article.
January 20, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29353231/the-preterm-heart-in-childhood-left-ventricular-structure-geometry-and-function-assessed-by-echocardiography-in-6-year-old-survivors-of-periviable-births
#6
Lilly-Ann Mohlkert, Jenny Hallberg, Olof Broberg, Annika Rydberg, Cecilia Pegelow Halvorsen, Petru Liuba, Vineta Fellman, Magnus Domellöf, Gunnar Sjöberg, Mikael Norman
BACKGROUND: Preterm birth has been associated with increased risk of cardiovascular morbidity in adult life. We evaluated whether preterm birth is associated with deviating cardiac structure and function before school start. METHODS AND RESULTS: In total, 176 children aged 6 years and born extremely preterm (EXPT; gestational age of 22-26 weeks) and 134 children born at term (control [CTRL]) were studied. We used echocardiography to assess left heart dimensions, geometry, and functions...
January 20, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29353162/monolayers-of-a-tetrazine-containing-gemini-amphiphile-interplays-with-biomembrane-lipids
#7
Hiromichi Nakahara, Masayori Hagimori, Takahiro Mukai, Osamu Shibata
The property of a newly synthesized tetrazine derivative comprised of double C18-saturated hydrocarbon chain (C18-rTz-C18) has been studied in situ at the air-water interface. C18-rTz-C18 or a gemini amphiphile contributes to restriction of its tetrazine moiety on the interface, which is expected to be used for bioimaging and analytical reagents. Herein, to understand lateral interactions between Tz and biomembrane constituents, we investigated the interfacial behavior of Langmuir monolayers composed of C18-rTz-C18 and biomembrane lipids such as DPPC, DPPG, DPPE, PSM, and Cholesterol (Ch)...
January 17, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29353080/atlantic-salmon-adapted-to-seawater-for-9-weeks-develop-a-robust-immune-response-to-salmonid-alphavirus-upon-bath-challenge
#8
L J Moore, J Jarungsriapisit, T O Nilsen, S Stefansson, G L Taranger, C J Secombes, H C Morton, S Patel
Pancreas disease (PD) caused by salmonid alphavirus (SAV) is the most serious viral disease in Norwegian aquaculture. Study of the immune response to SAV will aid preventative measures including vaccine development. The innate immune response was studied in Atlantic salmon infected by either bath immersion (BI) or by intra-muscular (i.m.) injection (IM) with SAV subtype 3, two and nine weeks after seawater transfer (Phases A and B respectively). Phase A results have been previously published (Moore et al., 2017) and Phase B results are presented here together with a comparison of results achieved in Phase A...
January 15, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29353059/ask-family-kinases-are-required-for-optimal-nlrp3-inflammasome-priming
#9
David E Place, Parimal Samir, Rajendra Karki, Benoit Briard, Peter Vogel, Thirumala-Devi Kanneganti
Activation of the multimeric inflammasome complex leads to inflammatory responses to biotic and abiotic triggers. The inflammasome sensor, Nod-like receptor family Pyrin domain containing 3 (NLRP3), is activated by a range of stimuli and is tightly regulated to restrict excessive inflammation. Because NLRP3 responds broadly to cellular insults and regulates cell death similar to the stress-activated apoptosis signal-regulating kinases 1 and 2 (ASK1/2), we hypothesized that ASK1/2 may regulate NLRP3 activity...
January 15, 2018: American Journal of Pathology
https://www.readbyqxmd.com/read/29352817/the-association-between-sexual-behaviours-and-initiation-of-post-secondary-education-in-south-africa
#10
Annah V Bengesai, Hafiz T A Khan, Russell Dube
Although young people in South Africa are growing up in an era where their socioeconomic circumstances are seemingly better than those of their parents' generation, they face greater risks in their trajectory to adulthood. This is mainly because the environment in which they are making sexual decisions is also rapidly evolving. Currently, South Africa has the highest prevalence of HIV and AIDS in the world among young people aged 15-24. This study examined the effect of sexual behaviours initiated in adolescence on enrolment in post-secondary education...
January 21, 2018: Journal of Biosocial Science
https://www.readbyqxmd.com/read/29352709/analysis-of-gut-microbiota-diversity-and-auxiliary-diagnosis-as-a-biomarker-in-patients-with-schizophrenia-a-cross-sectional-study
#11
Yang Shen, Jintian Xu, Zhiyong Li, Yichen Huang, Ye Yuan, Jixiang Wang, Meng Zhang, Songnian Hu, Ying Liang
With the advent of sequencing technology, characterization of schizophrenia with underlying probing of gut microbiome can provide abundant clues for diagnosis and prognosis of schizophrenia. In this study, we first compared the difference of gut microbiota between schizophrenia patients and healthy controls by 16S rRNA sequencing. We further explored whether gut microbiota can be used as a biomarker to assist in the diagnosis of schizophrenia. We restricted inclusion criteria strictly to control confounding bias...
January 15, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29352701/bailout-surgical-explantation-of-a-transcatheter-valve-in-valve-for-subacute-thrombosis-when-there-is-no-time-for-anticoagulation-case-report-and-literature-review
#12
Francesco Notaristefano, Matteo Rocco Reccia, Salvatore Notaristefano, Roberto Annunziata, Rocco Sclafani, Giuseppe Ambrosio, Claudio Cavallini
Trancatheter heart valve (THV) thrombosis is effectively treated with anticoagulation but alternative therapies are required when a faster gradient reduction is needed. Open heart surgery has been rarely performed due to the high perioperative mortality and only five cases have been described so far. Here we describe a case of emergent surgical explantation for THV thrombosis after a valve-in-valve. A 67years old man underwent transcatheter aortic valve implantation for a failed surgical bioprosthesis Epic 21mm (St...
December 13, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29352665/complementary-and-alternative-medicine-cam-practices-and-dietary-patterns-in-children-with-inflammatory-bowel-disease-in-singapore-and-malaysia
#13
Fangyi Ong, Way Seah Lee, Charlotte Lin, Ruey Terng Ng, Shin Yee Wong, Su Lin Lim, Seng Hock Quak, Marion Aw
BACKGROUND: The use of complementary and alternative medicine (CAM) has been associated with adverse effects and self-imposed dietary restrictions. The prevalence of its use in Asian children with inflammatory bowel disease (IBD) is unknown. We aimed to determine the prevalence, types, and factors associated with the use of CAM among children with IBD from Singapore and Malaysia, and to ascertain if dietary restriction was prevalent in patients who used CAM. METHODS: A cross-sectional study was conducted in which parents of children with IBD attending two tertiary pediatric IBD referral centres in Singapore and Malaysia were interviewed...
December 26, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29352637/the-ability-of-topical-and-systemic-statins-to-increase-osteogenesis-around-dental-implants-a-systematic-review-of-histomorphometric-outcomes-in-animal-studies
#14
REVIEW
V Moraschini, D C F Almeida, J A Calasans-Maia, M Diuana Calasans-Maia
The purpose of this systematic review was to evaluate the quantitative histomorphometric outcomes of animal studies investigating statins as a pro-osteogenic agent to enhance the osseointegration of dental implants. Some animal studies have suggested a beneficial action of statins on bone tissue. Electronic and manual literature searches, without date or language restriction, ​​were performed by two independent review authors up to February 2017. Eligibility criteria included animal trials quantitatively analysing the pro-osteogenic effect of statins on dental implants...
January 15, 2018: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29352556/what-causes-psychosis-an-umbrella-review-of-risk-and-protective-factors
#15
Joaquim Radua, Valentina Ramella-Cravaro, John P A Ioannidis, Abraham Reichenberg, Nacharin Phiphopthatsanee, Taha Amir, Hyi Yenn Thoo, Dominic Oliver, Cathy Davies, Craig Morgan, Philip McGuire, Robin M Murray, Paolo Fusar-Poli
Psychosis is a heterogeneous psychiatric condition for which a multitude of risk and protective factors have been suggested. This umbrella review aimed to classify the strength of evidence for the associations between each factor and psychotic disorders whilst controlling for several biases. The Web of Knowledge database was searched to identify systematic reviews and meta-analyses of observational studies which examined associations between socio-demographic, parental, perinatal, later factors or antecedents and psychotic disorders, and which included a comparison group of healthy controls, published from 1965 to January 31, 2017...
February 2018: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
https://www.readbyqxmd.com/read/29352514/an-integrative-review-exploring-the-physical-and-psychological-harm-inherent-in-using-restraint-in-mental-health-inpatient-settings
#16
Pauline Cusack, Frank Patrick Cusack, Sue McAndrew, Mick McKeown, Joy Duxbury
In Western society, policy and legislation seeks to minimize restrictive interventions, including physical restraint; yet research suggests the use of such practices continues to raise concerns. Whilst international agreement has sought to define physical restraint, diversity in the way in which countries use restraint remains disparate. Research to date has reported on statistics regarding restraint, how and why it is used, and staff and service user perspectives about its use. However, there is limited evidence directly exploring the physical and psychological harm restraint may cause to people being cared for within mental health inpatient settings...
January 19, 2018: International Journal of Mental Health Nursing
https://www.readbyqxmd.com/read/29352494/the-effects-of-late-gestation-nutrient-restriction-of-dams-on-beef-heifer-intake-metabolites-and-hormones-during-an-ad-libitum-feeding-trial
#17
J E Tipton, R E Ricks, C T LeMaster, N M Long
This study's objective was to determine if nutrient restriction during late gestation affected beef heifer feed intake, body weight (BW) gain and endocrine regulation during a 10-week feeding trial. During the last 100 days of gestation, control (CON) dams were fed to increase body condition score (BCS). Whereas, nutrient-restricted dams (NR) and NR dams protein supplemented 3 days/week (NRS) were fed to decrease BCS by 1.2. After parturition, all cow-calf pairs were moved to a common pasture and fed in excess of requirements until weaning...
January 19, 2018: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29352356/assessment-of-noise-level-and-noise-propagation-generated-by-light-lift-helicopters-in-mountain-natural-environments
#18
Stefano Grigolato, Omar Mologni, Andrea Rosario Proto, Giuseppe Zimbalatti, Raffaele Cavalli
The use of helicopter rises discussion about environmental noise propagation especially when it operates in proximity of environmentally sensitive areas (ESAs) for an extended period because of its potential implications in wildlife behaviours. In order to support decisions on helicopter logging operation management in proximity of ESAs, this study focused on (i) analysing the noise spectrum of a light-lift helicopter during logging operations and on (ii) assessing the noise propagation in the surrounding environments...
January 20, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29352116/the-chemical-fluctuation-theorem-governing-gene-expression
#19
Seong Jun Park, Sanggeun Song, Gil-Suk Yang, Philip M Kim, Sangwoon Yoon, Ji-Hyun Kim, Jaeyoung Sung
Gene expression is a complex stochastic process composed of numerous enzymatic reactions with rates coupled to hidden cell-state variables. Despite advances in single-cell technologies, the lack of a theory accurately describing the gene expression process has restricted a robust, quantitative understanding of gene expression variability among cells. Here we present the Chemical Fluctuation Theorem (CFT), providing an accurate relationship between the environment-coupled chemical dynamics of gene expression and gene expression variability...
January 19, 2018: Nature Communications
https://www.readbyqxmd.com/read/29352077/whole-genome-sequencing-of-suppressor-dna-mixtures-identifies-pathways-that-compensate-for-chromosome-segregation-defects-in-schizosaccharomyces-pombe
#20
Xingya Xu, Li Wang, Mitsuhiro Yanagida
Suppressor screening is a powerful method to identify genes that when mutated, rescue the temperature sensitivity of the original mutation. Previously, however, identification of suppressor mutations has been technically difficult. Due to the small genome size of Schizosaccharomyces pombe, we developed a spontaneous suppressor screening technique, followed by a cost-effective sequencing method. Genomic DNAs of 10 revertants which survived at the restrictive temperature of the original temperature sensitive (ts) mutant were mixed together as one sample before constructing a library for sequencing...
January 19, 2018: G3: Genes—Genomes—Genetics
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