#1
RANDOMIZED CONTROLLED TRIAL
Nudrat Jehangir Khan, Sara Haider, Haider Gilani, Neelam Iqbal, Syed Affan Ali, Mohammad Arshad Abbasi
BACKGROUND: World has been facing an epidemic of non-communicable diseases including heart, metabolic and renal diseases. Renal diseases have been commonly diagnosed and managed in low- and middle-income countries. Objective was to compare efficacy and safety of Pregabalin and Gabapentin in uremic pruritus among patients of chronic kidney injury undergoing haemodialysis. It was a comparative cross-sectional study, conducted at the Department of nephrology Abbottabad International Medical Institute...
2022: Journal of Ayub Medical College, Abbottabad: JAMC
#2
JOURNAL ARTICLE
Ashima Ravindran, Rajesh Peringanazhi Kunnath, Anjali Sunny, Binoo Vimal
Background: Uremic pruritus (UP) affects many patients suffering from chronic kidney disease (CKD) and has a negative impact on the quality of life. The severity of UP ranges from sporadic discomfort to complete restlessness during both day and night time. It has become increasingly evident that central transmission and sensitization processes similar to those observed in chronic pain are important mechanisms of pruritus. Methodology: This was a randomized single-blind prospective-interventional study carried out for 6 weeks...
July 2020: Indian Journal of Palliative Care
#3
RANDOMIZED CONTROLLED TRIAL
Mariele Gobo-Oliveira, Vitória G Pigari, Matheus Sp Ogata, Hélio A Miot, Daniela Ponce, Luciana Pf Abbade
BACKGROUND: Uremic pruritus is a common symptom in chronic renal failure patients with undefined pathophysiology. Initial treatment involves topical therapy mainly in the form of moisturizers, however, in many cases, this is not sufficient to relieve itching. Systemic adjuvant therapy is therefore necessary, which commonly includes oral antihistamines, with limited success. Positive effects have been reported for gabapentin. OBJECTIVES: To evaluate the efficacy and safety of gabapentin vs...
August 1, 2018: European Journal of Dermatology: EJD
#4
REVIEW
Eli Johanne Nordal, Ingrid Os
BACKGROUND: Itching commonly occurs in patients with chronic renal failure, and can be a most distressful and sometimes disabling symptom. METHOD: This article is based on literature identified through a Pubmed search, textbooks and own clinical experience. RESULTS AND INTERPRETATION: Inflammatory processes seem to be important in the pathogenesis of uremic pruritus; mechanisms for interference from others factors are not fully understood...
May 3, 2007: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
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