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https://www.readbyqxmd.com/read/29778947/dissociable-contributions-of-dorsal-and-ventral-striatal-regions-on-a-rodent-cost-benefit-decision-making-task-requiring-cognitive-effort
#1
Mason M Silveira, Melanie Tremblay, Catharine A Winstanley
Cognitive effort is a ubiquitous process, yet surprisingly little is known about the brain mechanisms responsible for evaluating it. Here, we utilize the rat Cognitive Effort Task (rCET) to probe the striatum's role in deciding between options that vary in the amount of cognitive effort required for success. In the rCET, animals choose to perform either an easy trial, in which the attentional demand is low but the potential reward is small, or a difficult trial which is more attentionally demanding but can yield twice the sugar pellets...
April 24, 2018: Neuropharmacology
https://www.readbyqxmd.com/read/29778931/monitoring-tool-usage-in-surgery-videos-using-boosted-convolutional-and-recurrent-neural-networks
#2
Hassan Al Hajj, Mathieu Lamard, Pierre-Henri Conze, Béatrice Cochener, Gwenolé Quellec
This paper investigates the automatic monitoring of tool usage during a surgery, with potential applications in report generation, surgical training and real-time decision support. Two surgeries are considered: cataract surgery, the most common surgical procedure, and cholecystectomy, one of the most common digestive surgeries. Tool usage is monitored in videos recorded either through a microscope (cataract surgery) or an endoscope (cholecystectomy). Following state-of-the-art video analysis solutions, each frame of the video is analyzed by convolutional neural networks (CNNs) whose outputs are fed to recurrent neural networks (RNNs) in order to take temporal relationships between events into account...
May 9, 2018: Medical Image Analysis
https://www.readbyqxmd.com/read/29778857/development-of-a-risk-score-based-on-aortic-calcification-to-predict-1-year-mortality-after-transcatheter-aortic-valve-replacement
#3
Pierre Lantelme, Hélène Eltchaninoff, Muriel Rabilloud, Géraud Souteyrand, Marion Dupré, Marco Spaziano, Marc Bonnet, Clément Becle, Benjamin Riche, Eric Durand, Erik Bouvier, Jean-Nicolas Dacher, Pierre-Yves Courand, Lucie Cassagnes, Eduardo E Dávila Serrano, Pascal Motreff, Loic Boussel, Thierry Lefèvre, Brahim Harbaoui
OBJECTIVES: The aim of this study was to develop a new scoring system based on thoracic aortic calcification (TAC) to predict 1-year cardiovascular and all-cause mortality. BACKGROUND: A calcified aorta is often associated with poor prognosis after transcatheter aortic valve replacement (TAVR). A risk score encompassing aortic calcification may be valuable in identifying poor TAVR responders. METHODS: The C4 CAPRI (4 Cities for Assessing CAlcification PRognostic Impact) multicenter study included a training cohort (1,425 patients treated using TAVR between 2010 and 2014) and a contemporary test cohort (311 patients treated in 2015)...
May 11, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29778763/oscillation-patterns-of-local-field-potentials-in-the-dorsal-striatum-and-sensorimotor-cortex-during-the-encoding-maintenance-and-decision-stages-for-the-ordinal-comparison-of-sub-and-supra-second-signal-durations
#4
REVIEW
Bon-Mi Gu, Keshav Kukreja, Warren H Meck
Ordinal comparison of successively presented signal durations requires a) the encoding of the first signal duration (standard), b) maintenance of temporal information specific to the standard duration in memory, and c) timing of the second signal duration (comparison) during which a comparison is made of the first and second durations. Rats were first trained to make ordinal comparisons of signal durations within three time ranges using 0.5, 1.0, and 3.0-s standard durations. Local field potentials were then recorded from the dorsal striatum and sensorimotor cortex in order to investigate the pattern of neural oscillations during each phase of the ordinal-comparison process...
May 17, 2018: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/29778518/an-innovative-medical-school-curriculum-to-address-human-papillomavirus-vaccine-hesitancy
#5
Abigail M Schnaith, Erica M Evans, Caleb Vogt, Andrea M Tinsay, Thomas E Schmidt, Katelyn M Tessier, Britt K Erickson
BACKGROUND: Vaccination rates against Human Papillomavirus (HPV) in the US remain alarmingly low. Physicians can significantly influence a parent's decision to vaccinate their children. However, medical education often lacks training on specific strategies for communicating with vaccine hesitant parents. METHODS: We created an innovative curriculum designed to teach medical students how to address HPV vaccine hesitancy. The curriculum consisted of (1) a presentation on the epidemiology, biology, and disease morbidity associated with HPV, (2) a video that teaches specific communication strategies and (3) role-playing simulations...
May 16, 2018: Vaccine
https://www.readbyqxmd.com/read/29778122/provider-language-proficiency-and-decision-making-when-caring-for-limited-english-proficiency-children-and-families
#6
Yolanda N Evans, Sarah A Rafton, Eriberto Michel, Beth E Ebel
OBJECTIVE: To examine associations between self-assessed language ability and provision of clinical care without professional interpretation. METHODS: We conducted an anonymous web-based survey of pediatric residents at a large pediatric training program. Respondents self-rated their language ability, and then reported on their willingness to deliver clinical care without professional interpretation in standardized clinical scenarios. RESULTS: All pediatric residents completed the survey (n=81; 100%)...
June 2018: Journal of the National Medical Association
https://www.readbyqxmd.com/read/29777650/modeling-dengue-vector-population-using-remotely-sensed-data-and-machine-learning
#7
Juan M Scavuzzo, Francisco Trucco, Manuel Espinosa, Carolina B Tauro, Marcelo Abril, Carlos M Scavuzzo, Alejandro C Frery
Mosquitoes are vectors of many human diseases. In particular, Aedes ægypti (Linnaeus) is the main vector for Chikungunya, Dengue, and Zika viruses in Latin America and it represents a global threat. Public health policies that aim at combating this vector require dependable and timely information, which is usually expensive to obtain with field campaigns. For this reason, several efforts have been done to use remote sensing due to its reduced cost. The present work includes the temporal modeling of the oviposition activity (measured weekly on 50 ovitraps in a north Argentinean city) of Aedes ægypti (Linnaeus), based on time series of data extracted from operational earth observation satellite images...
May 16, 2018: Acta Tropica
https://www.readbyqxmd.com/read/29777617/simulation-in-urology-to-train-non-technical-skills-in-ward-rounds
#8
K Somasundram, H Spence, A J Colquhoun, C Mcilhenny, C S Biyani, S Jain
OBJECTIVE: We have designed an exercise to train newly appointed Urology trainees in non-technical skills on ward rounds as a part of a simulation 'boot camp'. This paper reports our experience, including a qualitative analysis of participant feedback on the utility of this method of training. PATIENTS AND METHODS: The simulations took place in a high-fidelity simulated ward bay. Forty-eight doctors with formal Urology training ranging between 2-60 months (mean 19...
May 19, 2018: BJU International
https://www.readbyqxmd.com/read/29777464/the-key-features-approach-to-assess-clinical-decisions-validity-evidence-to-date
#9
REVIEW
G Bordage, G Page
The key-features (KFs) approach to assessment was initially proposed during the First Cambridge Conference on Medical Education in 1984 as a more efficient and effective means of assessing clinical decision-making skills. Over three decades later, we conducted a comprehensive, systematic review of the validity evidence gathered since then. The evidence was compiled according to the Standards for Educational and Psychological Testing's five sources of validity evidence, namely, Content, Response process, Internal structure, Relations to other variables, and Consequences, to which we added two other types related to Cost-feasibility and Acceptability...
May 17, 2018: Advances in Health Sciences Education: Theory and Practice
https://www.readbyqxmd.com/read/29775736/surgical-consent-practice-in-the-uk-following-the-montgomery-ruling-a-national-cross-sectional-questionnaire-study
#10
Chris McKinnon, Dafydd Loughran, Roísín Finn, Madeline Coxwell-Matthewman, Deva Sanjeeva Jeyaretna, Adam P Williams
BACKGROUND: The Supreme Court case of Montgomery vs Lanarkshire Health Board in 2015 was a landmark case for consent practice in the UK which shifted focus from a traditional paternalistic model of consent towards a more patient-centered approach. Widely recognised as the most significant legal judgment on informed consent in the last 30 years, the case was predicted to have a major impact on the everyday practice of surgeons working in the UK National Health Service (NHS). Two years after the legal definition of informed consent was redefined, we carried out an audit of surgical consent practice across the UK to establish the impact of the Montgomery ruling on clinical practice...
May 15, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29775510/educational-intervention-on-delirium-assessment-using-confusion-assessment-method-icu-cam-icu-in-a-general-intensive-care-unit
#11
Vimala Ramoo, Harlinna Abu, Vineya Rai, Surindar Kaur Surat Singh, Ayuni Asma' Baharudin, Mahmoud Danaee, Raveena Rajalachimi R Thinagaran
AIMS AND OBJECTIVES: The primary objective was to assess intensive care unit nurses' knowledge of intensive care unit delirium and delirium assessment before and after an educational intervention. In addition, nurses' perception on the usefulness of a delirium assessment tool and barriers against delirium assessment were assessed as secondary objectives. BACKGROUND: Early identification of delirium in intensive care units is crucial for patient care. Hence, nurses require adequate knowledge to enable appropriate evaluation of delirium using standardised practice and assessment tools...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29775421/probability-of-heat-intolerance-standardized-interpretation-of-heat-tolerance-testing-results-versus-specialist-judgment
#12
Haggai Schermann, Erin Craig, Einat Yanovich, Itay Ketko, Gary Kalmanovich, Ran Yanovich
CONTEXT:   The heat-tolerance test (HTT) is a screening tool for secondary prevention of exertional heat illness by the Israel Defense Forces. To discern participant tolerance, recruits are exposed to intermediate environmental and exercise stresses, and their physiological responses, core temperature, and heart rate are monitored. When their physiological measures rise at a higher rate or exceed the upper levels of absolute values compared with other participants, heat intolerance (HI) is diagnosed...
April 2018: Journal of Athletic Training
https://www.readbyqxmd.com/read/29775080/mindfulness-meditation-and-interprofessional-cardiopulmonary-resuscitation-a-mixed-methods-pilot-study
#13
Diana J Kelm, Jennifer L Ridgeway, Becca L Gas, Monali Mohan, David A Cook, Darlene R Nelson, Roberto P Benzo
PROBLEM: Mindfulness training includes mindfulness meditation, which has been shown to improve both attention and self-awareness. Medical providers in the intensive care unit often deal with difficult situations with strong emotions, life-and-death decisions, and both interpersonal and interprofessional conflicts. The effect of mindfulness meditation training on healthcare providers during acute care tasks such as cardiopulmonary resuscitation remains unknown. Mindfulness meditation has the potential to improve provider well-being and reduce stress in individuals involved in resuscitation teams, which could then translate into better team communication and delivery of care under stress...
May 18, 2018: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/29774777/current-research-status-of-palliative-care-in-mainland-china
#14
Tao Wang, Alex Molassiotis, Betty Pui Man Chung, Jing-Yu Tan
OBJECTIVES: This study aimed to obtain an overview of the current research status of palliative care in Mainland China and identify research directions for future studies by characterizing palliative care studies conducted among patients with any life-limiting illness in Mainland China and published in a peer-reviewed journal before November 2016. METHODS: A review guide with 7 categories was initially developed based on existing international palliative care definitions and guidelines through content analysis...
January 1, 2018: Journal of Palliative Care
https://www.readbyqxmd.com/read/29772447/one-to-one-specialling-and-sitters-in-acute-care-hospitals-a-scoping-review
#15
REVIEW
Victoria J Wood, Cecilia Vindrola-Padros, Nick Swart, Michelle McIntosh, Sonya Crowe, Stephen Morris, Naomi J Fulop
BACKGROUND: One to one specialling is a type of care which is provided to ensure the safety of patients who may be suffering from cognitive impairment, exhibit challenging behaviour, or may be at risk of falls or of causing harm to themselves or others. Care such as this, often referred to as 'specialling' or 'sitting' is common practice in most hospitals around the world, but there is a lack of evidence regarding its cost effectiveness and the quality of care provided. AIM: The aim of this scoping review was to explore the breadth and scope of literature on one to one specialling, sitters and similar types of care in acute secondary care settings, in order to identify the challenges and concerns relating to the quality of care (process and outcomes) and cost effectiveness emerging from the literature, and determine the implications of this for policy, practice and future research...
April 30, 2018: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29772102/novel-nomograms-for-castration-resistant-prostate-cancer-and-survival-outcome-in-patients-with-de-novo-bone-metastatic-prostate-cancer
#16
Jinge Zhao, Guangxi Sun, Banghua Liao, Xingming Zhang, Cameron M Armstrong, Xiaoxue Yin, Jiandong Liu, Junru Chen, Yaojing Yang, Peng Zhao, Qidun Tang, Zhenghao Wang, Zhibin Chen, Xiong Li, Qiang Wei, Xiang Li, Ni Chen, Allen C Gao, Pengfei Shen, Hao Zeng
OBJECTIVES: To develop nomograms predicting the incidence of castration resistant prostate cancer (CRPC) and overall survival (OS) for de novo metastatic prostate cancer (mPCa). MATERIALS AND METHODS: Data from 449 de novo mPCa patients were retrospectively analyzed. Patients were randomly divided into the training (n=314, 70%) and validation cohort (n=135, 30%). Predictive factors were selected by Cox-proportional model and further used for building predictive models...
May 17, 2018: BJU International
https://www.readbyqxmd.com/read/29772072/the-forensic-confirmation-bias-a-comparison-between-experts-and-novices
#17
Claire A J van den Eeden, Christianne J de Poot, Peter J van Koppen
A large body of research has described the influence of context information on forensic decision-making. In this study, we examined the effect of context information on the search for and selection of traces by students (N = 36) and crime scene investigators (N = 58). Participants investigated an ambiguous mock crime scene and received prior information indicating suicide, a violent death or no information. Participants described their impression of the scene and wrote down which traces they wanted to secure...
May 17, 2018: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29771930/perspectives-of-human-verification-via-binary-qrs-template-matching-of-single-lead-and-12-lead-electrocardiogram
#18
Vessela Krasteva, Irena Jekova, Ramun Schmid
OBJECTIVE: This study aims to validate the 12-lead electrocardiogram (ECG) as a biometric modality based on two straightforward binary QRS template matching characteristics. Different perspectives of the human verification problem are considered, regarding the optimal lead selection and stability over sample size, gender, age, heart rate (HR). METHODS: A clinical 12-lead resting ECG database, including a population of 460 subjects with two-session recordings (>1 year apart) is used...
2018: PloS One
https://www.readbyqxmd.com/read/29771817/high-value-cost-conscious-communication-skills-in-undergraduate-medical-education-validity-evidence-for-scores-derived-from-two-standardized-patient-scenarios
#19
Neena Natt, Stephanie R Starr, Darcy A Reed, Yoon Soo Park, Liselotte N Dyrbye, Andrea N Leep Hunderfund
INTRODUCTION: Training in high-value, cost-conscious care (HVCCC) is increasingly being incorporated into medical school curricula, but students may have limited opportunities to engage patients in HVCCC conversations. The aim of this study was to develop two standardized patient scenarios with associated checklists, hypothesizing that resulting scores would allow for valid formative assessments of HVCCC communication skills. METHODS: Scenarios were designed to generate a less-is-more conversation (in response to a patient requesting an unnecessary test) and a shared decision-making conversation (in response to a patient choosing between multiple effective treatment options)...
May 15, 2018: Simulation in Healthcare: Journal of the Society for Simulation in Healthcare
https://www.readbyqxmd.com/read/29771664/guided-policy-exploration-for-markov-decision-processes-using-an-uncertainty-based-value-of-information-criterion
#20
Isaac J Sledge, Matthew S Emigh, Jose C Principe
Reinforcement learning in environments with many action-state pairs is challenging. The issue is the number of episodes needed to thoroughly search the policy space. Most conventional heuristics address this search problem in a stochastic manner. This can leave large portions of the policy space unvisited during the early training stages. In this paper, we propose an uncertainty-based, information-theoretic approach for performing guided stochastic searches that more effectively cover the policy space. Our approach is based on the value of information, a criterion that provides the optimal tradeoff between expected costs and the granularity of the search process...
June 2018: IEEE Transactions on Neural Networks and Learning Systems
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