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https://www.readbyqxmd.com/read/28645030/uptake-and-tissue-distributions-of-cadmium-selenium-and-zinc-in-striped-marsh-frog-tadpoles-exposed-during-early-post-embryonic-development
#1
Chantal M Lanctôt, Tom Cresswell, Steven D Melvin
Metals and metalloids released through anthropogenic activities can accumulate in aquatic organisms, resulting in adverse effects in sensitive species. We investigated the influence of feeding regime and exposure complexity (i.e., mixture) on bioaccumulation kinetics and body distribution of common metal(loid) pollutants in Limnodynastes peronii during early post-embryonic development. Tadpoles were exposed to radiolabelled (109)Cd, (75)Se and (65)Zn alone and in a mixture for 4 days, followed by 3 days depuration in clean water...
June 20, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28645012/associations-between-toxic-and-essential-trace-elements-in-maternal-blood-and-fetal-congenital-heart-defects
#2
Yanqiu Ou, Michael S Bloom, Zhiqiang Nie, Fengzhen Han, Jinzhuang Mai, Jimei Chen, Shao Lin, Xiaoqing Liu, Jian Zhuang
Prenatal exposure to toxic trace elements, including heavy metals, is an important public health concern. Few studies have assessed if individual and multiple trace elements simultaneously affect cardiac development. The current study evaluated the association between maternal blood lead (Pb), cadmium (Cd), chromium (Cr), copper (Cu), mercury (Hg), and selenium (Se) levels and congenital heart defects (CHDs) in offspring. This hospital-based case-control study included 112 case and 107 control infants. Maternal peripheral blood draw was made during gestational weeks 17-40 and used to determine trace element levels by inductively coupled plasma mass spectrometry...
June 20, 2017: Environment International
https://www.readbyqxmd.com/read/28644466/characterization-of-a-selenocysteine-ligated-p450-compound-i-reveals-direct-link-between-electron-donation-and-reactivity
#3
Elizabeth L Onderko, Alexey Silakov, Timothy H Yosca, Michael T Green
Strong electron-donation from the axial thiolate ligand of cytochrome P450 has been proposed to increase the reactivity of compound I with respect to C-H bond activation. However, it has proven difficult to test this hypothesis, and a direct link between reactivity and electron donation has yet to be established. To make this connection, we have prepared a selenolate-ligated cytochrome P450 compound I intermediate. This isoelectronic perturbation allows for direct comparisons with the wild-type enzyme. Selenium incorporation was achieved using a cysteine auxotrophic Escherichia coli strain...
July 2017: Nature Chemistry
https://www.readbyqxmd.com/read/28643462/selenium-doped-carbon-quantum-dots-se-cqds-for-free-radical-scavenging
#4
Feng Li, Tianyu Li, Chenxing Sun, Jiahao Xia, Yang Jiao, Huaping Xu
Heteroatom doping is an effective way to adjust the fluorescent properties of carbon quantum dots. However, selenium-doped carbon dots have rarely been reported even though selenium has unique chemical properties like redox-responsive properties owing to its special electronegativity. Herein, a facile and high-output strategy to fabricate selenium-doped carbon quantum dots (Se-CQDs) with green fluorescence (quantum yield 7.6 %) is developed through the hydrothermal treatment of selenocystine under mild conditions...
June 23, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28643423/heterocorrole-conformations-little-saddling-much-ruffling
#5
Jörn Rösner, Birte Cordes, Stefanie Bahnmüller, Gabor Homolya, Dimitri Sakow, Peter Schweyen, Richard Wicht, Martin Bröring
10-Heterocorrole complexes with oxygen, sulfur, and selenium at position 10 of the macrocycle, and with the divalent ions of nickel, copper, and palladium were prepared and investigated. The focus was set onto the size adaptation and matching mechanisms of cavity sizes vs. ionic radii in corrole-type macrocycles. A full set of single crystal X-ray analyses was obtained and revealed that in all but one case the N4 binding site of the ring-contracted tetrapyrrole is larger than necessary to bind the metal ion without deformation...
June 23, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28642916/the-antioxidant-effect-of-beackea-frutescence-microemulsions-dietary-supplements-on-skin-absorption-studies
#6
Mohd Zul Helmi Rozaini, Armiza Ahmad, Azizul Idris, Chen Fei Low, Mohd Effendy Abdul Wahid
Objective: To study the effect of two different microemulsions containing Beackea frutescence supplements composed of nerolidool, selenium and vitamin E on absorption effect related to skin health and skin aging. Materials and methods: A total of 39 volunteers with normal and healthy skin were divided into three groups (n = 13) and supplemented for a period of 12 weeks. Group 1 received a mixture of lutein (3 mg/day), lycopene (3 mg/day), α-tocopherol (10 mg/day), selenium (75 μg/day) and β-nerolidool (4...
December 2016: Acta Biomaterialia Odontologica Scandinavica
https://www.readbyqxmd.com/read/28641283/-healing-of-amyotrophic-lateral-sclerosis-a-case-report
#7
Inge Mangelsdorf, Harald Walach, Joachim Mutter
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a devastating disease leading to death within 3-5 years in most cases. New approaches to treating this disease are needed. Here, we report a successful therapy. CASE REPORT: In a 49-year-old male patient suffering from muscle weakness and fasciculations, progressive muscular atrophy, a variant of ALS, was diagnosed after extensive examinations ruling out other diseases. Due to supposed mercury exposure from residual amalgam, the patient's teeth were restored...
June 12, 2017: Complementary Medicine Research
https://www.readbyqxmd.com/read/28641185/mechanistic-understanding-of-low-methylmercury-bioaccessibility-from-crayfish-procambarus-clarkii-muscle-tissue
#8
Qian Peng, Ben K Greenfield, Fei Dang, Yu Gong, Wenbo Bu, Huan Zhong
Recent research indicates that dietary exposure to mercury and other metals from crayfish consumption poses a human health concern, particularly in regions with high crayfish-consuming populations. To better understand consumption risk from methylmercury (MeHg), we quantified MeHg bioaccessibility in edible tail muscle of cooked red swamp crayfish (Procambarus clarkii, collected from seven cities in China), versus cooked fillet tissue of two finfish species: yellow croaker (Larimichthys polyactis) and snakehead (Channa argus)...
June 19, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28640579/rapid-and-robust-quantification-of-p-xyleneselenocyanate-in-plasma-via-derivatization
#9
Wenyi Zheng, Fadwa Benkessou, Brigitte Twelkmeyer, Siyao Wang, Tobias Ginman, Håkan Ottosson, Manuchehr Abedi-Valugerdi, Maria Angels Subirana, Ying Zhao, Moustapha Hassan
p-Xyleneselenocyanate (p-XSC) is one of the most investigated selenium compounds in cancer-prevention and -therapy. Despite the potent anti-cancer property, there is still no proper method to perform the quantitative analysis of p-XSC in plasma. In this investigation, we aimed at developing a method based on liquid chromatography-mass spectrometry (LC-MS) for the measurement of p-XSC in plasma. Direct deproteinization was first used to extract parent p-XSC from plasma, but failed to achieve high recovery rate (< 2%) due to formation of selenium-sulfur bond between p-XSC and plasma protein...
June 22, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28639965/is-selenium-supplementation-in-autoimmune-thyroid-diseases-justified
#10
Kristian H Winther, Steen Bonnema, Laszlo Hegedüs
PURPOSE OF REVIEW: This review provides an appraisal of recent evidence for or against selenium supplementation in patients with autoimmune thyroid diseases, and discusses possible effect mechanisms. RECENT FINDINGS: Epidemiological data suggest an increased prevalence of autoimmune thyroid diseases under conditions of low dietary selenium intake. Two systematic reviews have evaluated controlled trials among patients with autoimmune thyroiditis and report that selenium supplementation decreases circulating thyroid autoantibodies...
July 20, 2017: Current Opinion in Endocrinology, Diabetes, and Obesity
https://www.readbyqxmd.com/read/28638904/dissolution-behaviour-and-activation-of-selenium-in-phosphonium-based-ionic-liquids
#11
Tao Zhang, Kai Schwedtmann, Jan J Weigand, Thomas Doert, Michael Ruck
The dissolution behaviour of grey selenium in phosphonium based ionic liquids (ILs) has been investigated for the first time by (31)P and (77)Se nuclear magnetic resonance (NMR) experiments. The investigations evidence the formation of trialkylphosphane selenides which can serve as a selenium reservoir in the subsequent formation of metal selenides.
June 22, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28638832/the-response-of-macro-and-micronutrient-nutrient-status-and-biochemical-processes-in-rats-fed-on-a-diet-with-selenium-enriched-defatted-rapeseed-and-or-vitamin-e-supplementation
#12
Michaela Rýdlová, Karolína Růnová, Jiřina Száková, Alena Fučíková, Anna Hakenová, Petr Mlejnek, Václav Zídek, Jana Tremlová, Oto Mestek, Antonín Kaňa, Jarmila Zídková, Magdalena Melčová, Klára Truhlářová, Pavel Tlustoš
The response of nutrient status and biochemical processes in (i) Wistar and (ii) spontaneously hypertensive (SHR) rats upon dietary intake of selenium- (Se-) enriched defatted rapeseed (DRS) and/or vitamin E fortification was examined to assess the health benefit of DRS in animal nutrition. Twenty-four individuals of each type of rat were used: The control group was fed with an untreated diet (Diet A). In Diets B and C, soybean meal was replaced with defatted DRS, which comprised 14% of the total diet. The selenized DRS application resulted in ~3-fold increase of Se content in the diet...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28638225/sodium-selenite-ameliorates-dextran-sulfate-sodium-induced-chronic-colitis-in-mice-by-decreasing-th1-th17-and-%C3%AE-%C3%AE-t-and-increasing-cd4-cd25-regulatory-t-cell-responses
#13
Li-Xuan Sang, Bing Chang, Jun-Feng Zhu, Fang-Li Yang, Yan Li, Xue-Feng Jiang, Da-Nan Wang, Chang-Long Lu, Xun Sun
AIM: To assess the effect of sodium selenite on the severity of dextran sulfate sodium (DSS)-induced colitis in C57BL/6 mice. METHODS: Mice were randomly divided into four groups (n = 10/group): normal group, selenium (Se) group, chronic colitis group, and Se + chronic colitis group. The mice were sacrificed on day 26. Survival rates, clinical symptoms, colon length, and histological changes were determined. The percentages and absolute numbers of immune system cells in the lamina propria lymphocytes (LPL) of the colon, the expression of mRNA in colon tissue, and the concentrations of Th1, Th17, and Treg cytokines in LPL from the large intestine, were measured...
June 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28634813/long-term-excessive-selenium-supplementation-induces-hypertension-in-rats
#14
Denise Grotto, Maria Fernanda Hornos Carneiro, Michele Mazzaron de Castro, Solange Cristina Garcia, Fernando Barbosa Junior
Selenium (Se) is an essential trace element involved in several biological pathways, naturally found in rocks, soils, and food. Even though the daily requirement of Se is achieved through a balanced diet, the use of Se supplements has been frequent. Due to the risk of toxic effects of having Se in excess, supplementation is still under debate. The aim was to evaluate the effects of long-term Se supplementation upon systolic blood pressure (SBP) and redox status of rats exposed to sodium selenite. Male Wistar rats were exposed to 2 and 6 mg/L of sodium selenite in drinking water for 85 days...
June 20, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28634111/levels-of-plasma-selenium-and-urinary-total-arsenic-interact-to-affect-the-risk-for-prostate-cancer
#15
Yu-Mei Hsueh, Chien-Tien Su, Horng-Sheng Shiue, Wei-Jen Chen, Yeong-Shiau Pu, Ying-Chin Lin, Cheng-Shiuan Tsai, Chao-Yuan Huang
This study investigated whether plasma selenium levels modified the risk for prostate cancer (PC) related to arsenic exposure. We conducted a case-control study that included 318 PC patients and 318 age-matched, healthy control subjects. Urinary arsenic profiles were examined using HPLC-HG-AAS and plasma selenium levels were measured by ICP-MS. We found that plasma selenium levels displayed a significant dose-dependent inverse association with PC. The odds ratio (OR) and 95% confidence interval (CI) for PC was 0...
June 17, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28631307/interventions-for-the-prevention-of-recurrent-erysipelas-and-cellulitis
#16
REVIEW
Adam Dalal, Marina Eskin-Schwartz, Daniel Mimouni, Sujoy Ray, Walford Days, Emmilia Hodak, Leonard Leibovici, Mical Paul
BACKGROUND: Erysipelas and cellulitis (hereafter referred to as 'cellulitis') are common bacterial skin infections usually affecting the lower extremities. Despite their burden of morbidity, the evidence for different prevention strategies is unclear. OBJECTIVES: To assess the beneficial and adverse effects of antibiotic prophylaxis or other prophylactic interventions for the prevention of recurrent episodes of cellulitis in adults aged over 16. SEARCH METHODS: We searched the following databases up to June 2016: the Cochrane Skin Group Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, and LILACS...
June 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28630379/the-association-between-telomere-length-and-mortality-in-bangladesh
#17
Samantha G Dean, Chenan Zhang, Jianjun Gao, Shantanu Roy, Justin Shinkle, Mekala Sabarinathan, Maria Argos, Lin Tong, Alauddin Ahmed, Md Tariqul Islam, Tariqul Islam, Muhammad Rakibuz-Zaman, Golam Sarwar, Hasan Shahriar, Mahfuzar Rahman, Md Yunus, Joseph H Graziano, Lin S Chen, Farzana Jasmine, Muhammad G Kibriya, Habibul Ahsan, Brandon L Pierce
Telomeres are tandem repeat sequences at the end of chromosomes that bind proteins to protect chromosome ends. Telomeres shorten with age, and shorter leukocyte telomere length (TL) has been associated with overall mortality in numerous studies. However, this association has not been tested in populations outside of Europe and the U.S. We assessed the association between TL and subsequent mortality using data on 744 mortality cases and 761 age-/sex-matched controls sampled from >27,000 participants from three longitudinal Bangladeshi cohorts: Health Effects of Arsenic Longitudinal Study (HEALS), HEALS Expansion (HEALS-E), and Bangladesh Vitamin E and Selenium Trial (BEST)...
June 15, 2017: Aging
https://www.readbyqxmd.com/read/28629290/functional-foods-how-functional-are-they-a-case-report-of-supplement-induced-psychosis
#18
Priyanka Yadav, Kyle Stigall, Hannah E Johnson, Abner O Rayapati, Nitin Chopra
There is rising evidence of patients' use of alternative and complementary medicine. The percentage of the U.S. population who used at least one dietary supplement increased from 42% in 1988-1994 to 53% in 2003-2006. We present a case of an Asian female in her 40s, with no previous psychiatric illness, who presented to the emergency room following a brief psychotic episode, during which she self-amputated the tips of her fingers, after using multivitamins and herbal supplements including ginseng, gui yuan rou (Chinese herb), astaxanthin, goji (Chinese fruit), selenium, saw palmetto, grape seed extract, citrus bioflavanoid, lutein (zeaxantin), resvexatrol, sun chlorella, spirulina powder, phytoceramides, phytoestrogen, glucosatrin, bromelain plus, and American bee pollen...
August 2016: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/28628778/effects-of-incubation-time-and-filtration-method-on-kd-of-indigenous-selenium-and-iodine-in-temperate-soils
#19
T Almahayni, E Bailey, N M J Crout, G Shaw
In this study, the effects of incubation time and the method of soil solution extraction and filtration on the empirical distribution coefficient (Kd) obtained by de-sorbing indigenous selenium (Se) and iodine (I) from arable and woodland soils under temperate conditions were investigated. Incubation time had a significant soil- and element-dependent effect on the Kd values, which tended to decrease with the incubation time. Generally, a four-week period was sufficient for the desorption Kd value to stabilise...
June 16, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28627947/-the-standardized-mortality-numbers-of-patients-with-gastrointestinal-tumors-and-cardiovascular-diseases-in-four-wine-regions-and-in-one-not-wine-region-of-hungary-between-2000-2010
#20
János Nagy, Sándor Sipka, Judit Kocsis, Zsolt Horváth
INTRODUCTION: Eating habits act on mortalities from gastrointestinal tumors and cardiovascular diseases. AIM: To investigate the role of wine drinking on these mortalities in Hungary. METHOD: The standardized mortality data of people from 206,159 subjects died of gastrointestinal tumors and cardiovascular diseases between 2000-2010 were compared in four wine regions: Tokaj (white), Eger (red), Balaton (white), Szekszárd/Villány (red) and in Hódmezővásárhely (not-wine region)...
June 2017: Orvosi Hetilap
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