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https://www.readbyqxmd.com/read/28725499/the-effect-of-metacarpophalangeal-joint-hyperextension-on-outcomes-in-the-surgical-treatment-of-carpometacarpal-joint-arthritis
#1
David M Brogan, Rose M van Hogezand, Nikola Babovic, Brian Carlsen, Sanjeev Kakar
Purpose  In the surgical treatment of thumb carpometacarpal (CMC) joint arthritis, the effect of mild preoperative metacarpophalangeal (MCP) hyperextension on postoperative functional outcomes is unknown. We sought to examine outcomes after surgical treatment of CMC arthritis in patients with and without mild preexisting MCP deformity. Methods  A retrospective review was conducted to analyze the functional outcomes of patients treated for CMC arthritis at a single institution from March 1998 to May 2009...
August 2017: Journal of Wrist Surgery
https://www.readbyqxmd.com/read/28719976/radiographic-analysis-of-simulated-first-dorsal-interosseous-and-opponens-pollicis-loading-upon-thumb-cmc-joint-subluxation-a-cadaver-study
#2
Julie E Adams, Virginia O'Brien, Erik Magnusson, Benjamin Rosenstein, David J Nuckley
BACKGROUND: Therapy programs to treat thumb carpometacarpal (CMC) arthritis may engage selective activation and reeducation of thenar muscles, particularly the first dorsal interosseous (FDI) and opponens pollicis (OP) to reduce subluxation of the joint. We describe the effect of simulated selective activation of the FDI and OP muscles upon radiographic subluxation of the thumb CMC joint. METHODS: In a cadaver model of CMC subluxation, loads were applied to the FDI, the OP, and then concomitantly at 0%, 25%, 50%, 75%, and 100% maximal loads and radial subluxation of the joint and reduction in subluxation was measured...
February 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28584977/andrographolide-benefits-rheumatoid-arthritis-via-inhibiting-mapk-pathways
#3
Zun-Zhong Li, Ju-Peng Tan, Li-Li Wang, Qing-Hua Li
Andrographolide (AD) is the main compound distributed in medicinal herb Andrographis paniculata and exhibits anti-inflammatory activity. AD has been used for the treatment of multiple inflammatory diseases. However, the therapeutic value of AD on human rheumatoid arthritis (RA) remains unclear. In this study, we investigated the effects of AD on collagen-induced arthritis (CIA) and human RA synovial fibroblasts (RA-SFs). CIA mice were treated with AD (dissolved in 0.5% CMC-Na, 100 mg/kg per day) or vehicle (0...
June 6, 2017: Inflammation
https://www.readbyqxmd.com/read/28478845/influence-of-age-and-gender-on-normative-passive-range-of-motion-values-of-the-carpometacarpal-joint-of-the-thumb
#4
Joyce White, Lisa Coppola, Andrea Skomurski, Emma Mitchell-Rekrut
STUDY DESIGN: Cross-sectional clinical measurement study. INTRODUCTION: The carpometacarpal (CMC) joint of the thumb is a complex joint making accurate measurement of range of motion (ROM) challenging. There are limited normative data available to base rehabilitative decisions, which is unfortunate as this joint is frequently affected by arthritis and is critical to hand function. PURPOSE OF THE STUDY: To provide passive ROM values for the first CMC joint and investigate the effects of age and gender...
May 3, 2017: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
https://www.readbyqxmd.com/read/28465206/thumb-carpometacarpal-joint-denervation-for-primary-osteoarthritis-a-prospective-study-of-31-thumbs
#5
T Giesen, H J Klein, A Franchi, J A Medina, D Elliot
We present the results of a prospective study of 31 thumbs in 30 patients affected by primary osteoarthritis at the thumb carpometacarpal (CMC1) joint who were treated with denervation of the involved joint. For every operated hand, the Kapandji score, key-pinch strength, grip strength and pain on a visual analogue scale were evaluated preoperatively and postoperatively at 2 weeks, 6 weeks, 3 months, 6 months and 1 year. The patients' satisfaction was determined. The Kapandji score and key-pinch strength improved significantly in all patients...
June 2017: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/28160900/evidence-based-practice-in-the-surgical-treatment-of-thumb-carpometacarpal-joint-arthritis
#6
Frank Yuan, Oluseyi Aliu, Kevin C Chung, Elham Mahmoudi
PURPOSE: Thumb carpometacarpal (CMC) arthritis contributes considerably to functional disability in the aging adult United States (US) population. Owing to the increasing growth in this segment of our population, its burden on health care resources will increase in the future. Variations exist in the degree of complexity and cost among different surgical treatments. We examined the national trends of the surgical treatment of thumb CMC arthritis and hypothesized that current practice patterns are not supported by evidence favoring the simpler trapeziectomy-only procedure...
February 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28149211/biomechanical-comparison-of-suture-button-suspensionplasty-and-lrti-for-basilar-thumb-arthritis
#7
Mihir J Desai, David M Brogan, Marc J Richard, Suhail K Mithani, Fraser J Leversedge, David S Ruch
Background: The purpose of this study was to compare the initial biomechanical strength of trapeziectomy and suture-button suspensionplasty (SBS) with ligament reconstruction and tendon interposition (LRTI) for thumb carpometacarpal (CMC) arthritis in a cadaveric model. Methods: Eight matched pairs of below-elbow cadaveric arms were used for this study. Each specimen was randomly assigned to either receive a trapeziectomy and LRTI (LRTI group) or trapeziectomy and SBS (SBS group). Using previously described and validated testing protocols, physiological key pinch was simulated...
December 2016: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/27924250/first-carpo-metacarpal-joint-arthritis-interpositional-arthroplasty-using-trapezium
#8
Chirag Kapoor, Ankur Kansagra, Maulik Jhaveri, Aditya Merh, Paresh Golwala
Thumb pain secondary to arthritis at the basal joint of the thumb is a common condition, especially in women, and can be quite disabling. An accurate diagnosis can be readily made from the history and examination. Reconstructive procedures for each stage of the disease are aimed at relieving pain and restoring thumb motion and strength. There are a number of methods available to treat this condition both conservatively and surgically with variable success rates. We present a case of a middle-aged female with first carpo-metacarpal (CMC) joint arthritis in whom we have tried a new technique in which the trapezium is excised, crushed, put in a sponge covering and then inserted back in the void created after excision...
November 3, 2016: Curēus
https://www.readbyqxmd.com/read/27803128/stat-mutations-as-program-switchers-turning-primary-immunodeficiencies-into-autoimmune-diseases
#9
REVIEW
Tiziana Lorenzini, Laura Dotta, Mauro Giacomelli, Donatella Vairo, Raffaele Badolato
STAT proteins are a family of transcription factors that mediate cellular response to cytokines and growth factors. Study of patients with familial susceptibility to pathogens and/or autoimmune diseases has led to the identification of 7 inherited disorders that are caused by mutations of 4 STAT family genes. Homozygous or compound heterozygous mutations of STAT1 lead to complete or partial forms of STAT1 deficiency that are associated with susceptibility to intracellular pathogens and herpetic infections. Patients with heterozygous STAT1 gain-of-function (GOF) mutations usually present with chronic mucocutaneous candidiasis (CMC) but may also experience bacterial and viral infections, autoimmune manifestations, lymphopenia, cerebral aneurysms, and increased risk to develop tumors...
January 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/27517022/measurement-of-quality-of-life-among-patient-undergoing-arthroplasty-of-the-thumb-to-treat-cmc-arthritis
#10
Marcio Aurélio Aita, Rafael Saleme Alves, Luis Felipe Longuino, Carlos Henrique Vieira Ferreira, Douglas Hideki Ikeuti, Luciano Muller Reis Rodrigues
OBJECTIVE: To present the clinical and functional results, including measurement of quality of life, of patients undergoing trapeziometacarpal arthroplasty. METHOD: This was a prospective evaluation on 45 patients (53 thumbs) with a diagnosis of idiopathic rhizarthrosis who underwent resection arthroplasty and interposition of an uncemented Ascension(®) implant, made of pyrocarbon. The clinical and functional results were analyzed through radiography, range of motion (ROM) in degrees (°), visual analog scale (VAS) for pain and the disability of arm, shoulder and hand (DASH) questionnaire for quality of life...
July 2016: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/27418894/increased-complications-in-trapeziectomy-with-ligament-reconstruction-and-tendon-interposition-compared-with-trapeziectomy-alone
#11
Aparajit Naram, Keith Lyons, Douglas M Rothkopf, Edward R Calkins, Thomas Breen, Marci Jones, John V Shufflebarger
BACKGROUND: In the treatment of basal joint arthritis of the thumb, recent studies suggest equivalent outcomes with regard to long-term pain, mobility, and strength, in patients undergoing either trapeziectomy alone or trapeziectomy with ligament reconstruction and tendon interposition (LRTI). The goal of this study was to investigate risk factors for complications in carpometacarpal (CMC) arthroplasty. METHODS: We conducted a retrospective chart review of 5 surgeons at a single institution performing CMC arthroplasties from November 2006 to November 2012...
March 2016: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/27390569/arthroscopic-trapeziectomy-with-suture-button-suspensionplasty-a-retrospective-review-of-153-cases
#12
Genevieve Landes, Michael P Gaspar, Peter Goljan, Sidney M Jacoby, Abdo Bachoura, Randall W Culp
BACKGROUND: Arthroscopic trapeziectomy with suture button suspensionplasty (ATBS) is a relatively new surgical option for the treatment of thumb carpometacarpal (CMC) osteoarthritis. Although ATBS has many potential benefits over alternative surgical treatments for CMC arthritis, little data exist regarding its safety and complication rates. The purpose of this study was to demonstrate that ATBS is associated with a low risk of complications within 1 year of surgery. METHODS: A retrospective review of patients treated with ATBS by one senior hand surgeon over a span of 3 years was performed...
June 2016: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/27104081/extensor-pollicis-longus-rupture-after-mini-tightrope-suspensionplasty
#13
Mani Seetharaman, Mark A Vitale, Kapil Desai, John F Crowe
Background Arthritis of the first carpometacarpal (CMC) joint has been surgically treated in multiple ways with varying levels of success as measured by subjective and objective measures. Trapeziectomy with numerous variations in suspensionplasty comprises one of the more commonly used surgical procedures. Recently, the Mini TightRope apparatus has been utilized as a new method for achieving suspensionplasty, and as such lacks significant review of use and safety in the literature. Case Description An extensor pollicis longus (EPL) rupture following a trapeziectomy and Mini TightRope suspensionplasty for CMC arthritis of the thumb is presented...
May 2016: Journal of Wrist Surgery
https://www.readbyqxmd.com/read/27077466/suspension-arthroplasty-for-old-fracture-dislocations-of-the-fifth-carpometacarpal-joint
#14
Naoki Kato, Keizo Fukumoto
It is well known that treatment of the old fracture-dislocations of the fifth carpometacarpal (CMC) joint is challenging. For patients with persistent pain due to this condition, numerous surgical techniques have been proposed. Here, we present a novel surgical technique, CMC joint suspension arthroplasty, using a partial slip of the extensor carpi ulnaris tendon. This procedure follows principles similar to the procedure of trapeziectomy with suspension arthroplasty for treatment of thumb CMC joint arthritis...
June 2016: Techniques in Hand & Upper Extremity Surgery
https://www.readbyqxmd.com/read/26948999/painful-thumb-carpometacarpal-joint-osteoarthritis-results-of-a-novel-treatment-approach
#15
Denis Ehrl, Holger C Erne, P Niclas Broer, Christian Metz, Erwin Falter
BACKGROUND: Pain reduction as well as preservation and improvement in range of motion remain the main aims in the treatment of thumb carpometacarpal (CMC) osteoarthritis (OA). We performed a retrospective outcome analysis of patients with symptomatic stage II-III thumb CMC joint arthritis treated with denervation, joint lavage and capsular imbrication. METHODS: 73 patients with stage II to III OA of the thumb CMC-joint underwent the described technique. A total of 42 patients complied with follow-up assessment and were included in this study...
July 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/26890509/midcarpal-and-scaphotrapeziotrapezoid-arthritis-in-patients-with-carpometacarpal-arthritis
#16
Evan B Katzel, Dierde Bielicka, Sameer Shakir, John Fowler, Glenn A Buterbaugh, Joseph E Imbriglia
BACKGROUND: Carpometacarpal arthroplasty provides well-documented pain relief with preservation of thenar function in basal joint arthritis treatment. Nevertheless, some patients continue to have pain following surgery. The authors hypothesize that unrecognized midcarpal (capitolunate) arthritis is a contributor to persistent pain after carpometacarpal arthroplasty. The prevalence of midcarpal arthritis in patients with basal joint arthritis is unknown. This article establishes the radiographic prevalence of midcarpal arthritis in patients with carpometacarpal arthritis...
June 2016: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/26823066/residual-effects-of-restless-sleep-over-depressive-symptoms-on-chronic-medical-conditions-race-by-gender-differences
#17
Shervin Assari, Amanda Sonnega, Renee Pepin, Amanda Leggett
BACKGROUND: Sleep and depression are comorbid problems that contribute to the development of chronic medical conditions (CMC) over time. Although racial and gender differences in the bidirectional associations between sleep, depression, and CMC are known, very limited information exists on heterogeneity of the residual effects of sleep problems over depressive symptoms on CMC across race by gender groups. AIM: Using a life-course perspective, the present study compared race by gender groups for residual effects of restless sleep over depressive symptoms on CMC...
February 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/26693500/black-white-differences-in-the-effect-of-baseline-depressive-symptoms-on-deaths-due-to-renal-diseases-25-year-follow-up-of-a-nationally-representative-community-sample
#18
Shervin Assari, Sarah Burgard
INTRODUCTION: More studies are needed to examine whether race moderates the effect of baseline depressive symptoms on cause-specific mortality including deaths due to renal diseases in the United States. OBJECTIVES: The present longitudinal study compared Blacks and Whites for the effect of baseline depressive symptoms on deaths due to renal diseases over a 25-year period in a nationally representative community sample. PATIENTS AND METHODS: Data came from the Americans' Changing Lives (ACL) study, a nationally representative cohort that followed 3361 Black (n = 1156) or White (n = 2205) adults 25 and older for up to 25 years from 1986 to 2011...
2015: Journal of Renal Injury Prevention
https://www.readbyqxmd.com/read/26493987/weaker-functional-pinch-strength-is-associated-with-early-thumb-carpometacarpal-osteoarthritis
#19
Thomas J McQuillan, Deborah Kenney, Joseph J Crisco, Arnold-Peter Weiss, Amy L Ladd
BACKGROUND: The thumb carpometacarpal (CMC) joint orchestrates pinch in its various positions, and thumb CMC osteoarthritis (OA) is a major source of orthopaedic morbidity. Self-reported pain, weakness, and physical examination may not correspond to radiographic findings when diagnosing early thumb CMC OA. Weakness is a prominent feature of the disease, but little evidence exists to quantify self-reported loss of strength with time, or to compare weakness with that of a nonarthritic population during early disease...
February 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/26443775/patients-with-thumb-carpometacarpal-arthritis-have-quantifiable-characteristic-expectations-that-can-be-measured-with-a-survey
#20
Lana Kang, Sohaib Z Hashmi, Joseph Nguyen, Steve K Lee, Andrew J Weiland, Carol A Mancuso
BACKGROUND: Although patient expectations associated with major orthopaedic conditions have shown clinically relevant and variable effects on outcomes, expectations associated with thumb carpometacarpal (CMC) arthritis have not been identified, described, or analyzed before, to our knowledge. QUESTIONS/PURPOSES: We asked: (1) Do patients with thumb CMC arthritis express characteristic expectations that are quantifiable and have measurable frequency? (2) Can a survey on expectations developed from patient-derived data quantitate expectations in patients with thumb CMC arthritis? METHODS: The study was a prospective cohort study...
January 2016: Clinical Orthopaedics and related Research
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