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https://www.readbyqxmd.com/read/28823098/modified-rapid-immunohistochemical-staining-for-intraoperative-diagnosis-of-malignant-brain-tumors
#1
Akane Suzuki, Takashi Maruyama, Masayuki Nitta, Takashi Komori, Soko Ikuta, Takakazu Kawamata, Yoshihiro Muragaki
Rapid immunohistochemistry (R-IHC) has been developing mainly as a support technique in the rapid diagnosis of central nervous system tumors; however, there have been problems regarding instability in specimen preparation and immunostaining. To overcome the weakness of this technology, the instability of immunostaining, we developed a modified R-IHC. This was achieved by switching to 4% paraformaldehyde as the fixative solution and utilizing a commercially available Polymer Refine Detection Kit, as a high-sensitivity kit, in place of the secondary antibodies...
August 19, 2017: Brain Tumor Pathology
https://www.readbyqxmd.com/read/28823051/imaging-features-of-glenoid-bare-spot-in-a-pediatric-population
#2
Sahlya Djebbar, Zehava Sadka Rosenberg, Erin Fitzgerald Alaia, Christoph Agten, Jonathan Zember, Ignacio Rossi
OBJECTIVE: The bare spot (BaS) is a central, well-circumscribed focal defect in the glenoid articular surface, with reported adult incidence of 1-2%. We aimed to reassess MRI features of BaS in the pediatric population and determine its etiology. MATERIALS AND METHODS: A retrospective search of our database from June 2014 to October 2015 was performed for shoulder MRI in patients between 5 and 25 years and then subdivided into four groups: group 1, 5-10 years; group 2, 10-15 years; group 3, 15-18 years; group 4, 20-25 years...
August 19, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28823013/dynamics-of-total-microcystin-lr-concentration-in-three-subtropical-hydroelectric-generation-reservoirs-in-uruguay-south-america
#3
Mauricio González-Piana, Daniel Fabián, Andrea Piccardo, Guillermo Chalar
This study analyzed the temporal dynamics of total microcystin LR concentrations between the years of 2012 and 2015 in the Bonete, Baygorria and Palmar hydroelectric generation reservoirs in the central region of the Negro River, Uruguay. The three reservoirs showed differents total microcystin LR concentration, with no significant differences among them. Over 20 sampling dates, the three reservoirs exhibited total microcystin LR concentrations on eight occasions that corresponded to a slight to moderate human health risk according to WHO guideline values for recreational waters...
August 20, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28822976/persistence-after-treatment-of-pharyngeal-gonococcal-infections-in-patients-of-the-sti-clinic-amsterdam-the-netherlands-2012-2015-a-retrospective-cohort-study
#4
I Putu Yuda Hananta, Henry John Christiaan De Vries, Alje P van Dam, Martijn Sebastiaan van Rooijen, Hardyanto Soebono, Maarten Franciscus Schim van der Loeff
INTRODUCTION: Infection of Neisseria gonorrhoeae in the pharynx (pharyngeal Ng) is associated with gonococcal transmission and development of antimicrobial resistance. We assessed proportion of and determinants for persistence after treatment of pharyngeal Ng. METHODS: At the STI clinic of Amsterdam, the Netherlands, females-at-risk and men who have sex with men are routinely screened for pharyngeal Ng using an RNA-based nucleic acid amplification test (NAAT; Aptima Combo 2)...
August 19, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28822971/second-hand-smoke-exposure-in-homes-with-children-assessment-of-airborne-nicotine-in-the-living-room-and-children-s-bedroom
#5
Teresa Arechavala, Xavier Continente, Mónica Pérez-Ríos, Anna Schiaffino, Esteve Fernandez, Núria Cortés-Francisco, Francesc Centrich, Glòria Muñoz, Maria J López
BACKGROUND: The introduction of 'smoke-free laws' has reduced the population's exposure to second-hand smoke (SHS), although SHS is still an issue in homes and other public places. Children are vulnerable to its health effects, and their greatest exposure occurs at home. OBJECTIVES: To assess airborne nicotine concentration of the living room and children's bedroom of homes with children under 13 years of age, and to analyse factors associated with these levels...
August 19, 2017: Tobacco Control
https://www.readbyqxmd.com/read/28822787/global-regional-and-national-deaths-prevalence-disability-adjusted-life-years-and-years-lived-with-disability-for-chronic-obstructive-pulmonary-disease-and-asthma-1990-2015-a-systematic-analysis-for-the-global-burden-of-disease-study-2015
#6
(no author information available yet)
BACKGROUND: Chronic obstructive pulmonary disease (COPD) and asthma are common diseases with a heterogeneous distribution worldwide. Here, we present methods and disease and risk estimates for COPD and asthma from the Global Burden of Diseases, Injuries, and Risk Factors (GBD) 2015 study. The GBD study provides annual updates on estimates of deaths, prevalence, and disability-adjusted life years (DALYs), a summary measure of fatal and non-fatal disease outcomes, for over 300 diseases and injuries, for 188 countries from 1990 to the most recent year...
August 16, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28822749/dominance-of-layer-specific-microvessel-dilation-in-contrast-enhanced-high-resolution-fmri-comparison-between-hemodynamic-spread-and-vascular-architecture-with-clarity
#7
REVIEW
Alexander John Poplawsky, Mitsuhiro Fukuda, Bok-Man Kang, Jae Hwan Kim, Minah Suh, Seong-Gi Kim
Contrast-enhanced cerebral blood volume-weighted (CBVw) fMRI response peaks are specific to the layer of evoked synaptic activity (Poplawsky et al., 2015), but the spatial resolution limit of CBVw fMRI is unknown. In this study, we measured the laminar spread of the CBVw fMRI evoked response in the external plexiform layer (EPL, 265 ± 65 μm anatomical thickness, mean ± SD, n = 30 locations from 5 rats) of the rat olfactory bulb during electrical stimulation of the lateral olfactory tract and examined its potential vascular source...
August 16, 2017: NeuroImage
https://www.readbyqxmd.com/read/28822746/outcomes-of-early-adolescent-donor-hearts-in-adult-transplant-recipients
#8
Shivank Madan, Snehal R Patel, Peter Vlismas, Omar Saeed, Sandhya Murthy, Stephen Forest, William Jakobleff, Daniel Sims, Jacqueline M Lamour, Daphne T Hsu, Julia Shin, Daniel Goldstein, Ulrich P Jorde
OBJECTIVES: This study sought to determine outcomes of adult recipients of early adolescent (EA) (10 to 14 years) donor hearts. BACKGROUND: Despite a shortage of donor organs, EA donor hearts (not used for pediatric patients) are seldom used for adults because of theoretical concerns for lack of hormonal activation and changes in left ventricular mass. Nonetheless, the outcomes of adult transplantation using EA donor hearts are not clearly established. METHODS: All adult (≥18 years of age) heart transplant recipients in the United Network for Organ Sharing database between April 1994 and September 2015 were eligible for this analysis...
August 3, 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28822732/gamma-phase-synchrony-in-autobiographical-memory-evidence-from-magnetoencephalography-and-severely-deficient-autobiographical-memory
#9
Lluís Fuentemilla, Daniela J Palombo, Brian Levine
The subjective sense of recollecting events from one's past is an essential feature of episodic memory, but the neural mechanisms supporting this capacity are poorly understood. We examined the role of large-scale patterns of neural synchrony using whole-head MEG recordings in healthy adults and S.M., who has severely deficient autobiographical memory (SDAM; Palombo et al., 2015), a syndrome in which autobiographical recollection is absent but other functions (including other mnemonic functions), are normal...
August 16, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28822726/recurrent-out-of-hospital-cardiac-arrest
#10
Ziad Nehme, Emily Andrew, Resmi Nair, Stephen Bernard, Karen Smith
BACKGROUND: Little is known about the burden of recurrent out-of-hospital cardiac arrest (OHCA) episodes in initial survivors of OHCA. We sought to investigate the frequency of recurrent OHCA, describe time-to-event trends, and establish baseline predictors of occurrence. METHODS: Between January 2000 and June 2015, we included consecutive OHCA survivors to hospital discharge from the Victorian Ambulance Cardiac Arrest Registry. Patient identifiers were used to match index and recurrent episodes of OHCA, and death records from a government database...
August 16, 2017: Resuscitation
https://www.readbyqxmd.com/read/28822721/postural-assessment-in-class-iii-patients-before-orthognathic-surgery
#11
Fernando Zugno Kulczynski, Fernando de Oliveira Andriola, Pedro Henrique Deon, Denizar Alberto da Silva Melo, Rogério Miranda Pagnoncelli
PURPOSE: To determine the postural characteristics of patients with Class III dentofacial deformities before orthognathic surgery by photogrammetry using SAPO postural assessment software. MATERIALS AND METHODS: This was a cross-sectional study. Eligible participants were adult patients who had an indication for orthognathic surgery to correct skeletal Class III dentofacial deformities and were undergoing orthodontic preparation for surgery. Patients were recruited at the outpatient clinic for dentofacial deformities of the authors' institution from March to November 2015...
July 25, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28822713/incidence-of-cross-infection-in-liver-transplant-patients-risk-factors-and-role-of-nursinge
#12
M Carmen Cierco Garrido, Raquel García Muñoz, Immaculada Pérez Castro, Miquel Sanz Moncusi
OBJECTIVE: To determine the incidence and risk factors of infection in liver transplant recipients immediately post-transplant, during admission to a liver transplant unit during the immediate post-transplant admission. METHODOLOGY: Descriptive, prospective study performed in the Liver Transplant Unit of Hospital Clínic, Barcelona. All liver transplant recipients between January 2012 and August 2015 (n=241) were included. Statistical analysis was performed with R Commander...
August 16, 2017: Enfermería Clínica
https://www.readbyqxmd.com/read/28822673/the-financial-impact-of-a-hospital-based-care-coordination-program-for-children-with-special-health-care-needs
#13
Janine M Petitgout
Care coordination programs are important in caring for medically complex pediatric patients, particularly for children with special health care needs. This study is a retrospective financial analysis of a hospital-based care coordination program involving one procedural subgroup of children with special health care needs: those receiving pediatric tracheostomy. Hospital records were reviewed for patients who received a tracheostomy at a large Midwestern U.S. hospital from 1999 through 2015. The population was divided into two subgroups: patients who received a tracheostomy before the development of a care coordination program and patients who received a tracheostomy after enrollment in the care coordination program...
August 16, 2017: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/28822658/preoperative-anemia-is-associated-with-mortality-after-carotid-endarterectomy-in-symptomatic-patients
#14
Alexander B Pothof, Thomas C F Bodewes, Thomas F X O'Donnell, Sarah E Deery, Katie Shean, Peter A Soden, Gert J de Borst, Marc L Schermerhorn
OBJECTIVE: Preoperative anemia and blood transfusions are associated with worse outcomes after surgery. However, the impact of preoperative anemia and transfusions on outcomes after carotid endarterectomy (CEA) is unknown. METHODS: CEA patients from 2011 to 2015 in the American College of Surgeons National Surgical Quality Improvement Program Targeted Vascular module were compared by the presence of preoperative anemia (hematocrit <36%) after stratification by symptom status...
August 16, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28822655/a-national-vascular-quality-initiative-database-comparison-of-hybrid-and-open-repair-for-aortoiliac-femoral-occlusive-disease
#15
Marco Zavatta, Matthew W Mell
OBJECTIVE: We sought to analyze the outcomes of revascularization for aortoiliac-femoral occlusive disease by comparing hybrid repair by endovascular revascularization and open common femoral endarterectomy (ER-CFE) with open aortoiliac reconstruction and CFE (OR-CFE). METHODS: Using the national Society for Vascular Surgery Vascular Quality Initiative database from 2009 to 2015, we identified all patients receiving open or endovascular revascularization of the aortoiliac system and who additionally underwent CFE...
August 16, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28822640/comparison-of-outcomes-1%C3%A2-year-after-rotator-cuff-repair-with-and-without-concomitant-biceps-surgery
#16
Scott T Watson, Christopher B Robbins, Asheesh Bedi, James E Carpenter, Joel J Gagnier, Bruce S Miller
PURPOSE: To compare the outcomes of patients who undergo a long head of the biceps (LHB) procedure (tenotomy or tenodesis) concomitant with rotator cuff repair (RCR) to those of patients who undergo isolated RCR. METHODS: Prospectively collected data were retrospectively reviewed on 80 patients, >18 years old, who underwent repair of a full-thickness rotator cuff tear and with 1-year patient-reported outcome scores collected June 2012 to March 2015. The exclusion criteria were concomitant procedures other than LHB tenotomy, tenodesis, or subacromial decompression; prior shoulder surgery; or other shoulder pathology...
August 16, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28822628/retrospective-cohort-study-of-cervical-pessary-use-in-women-with-short-cervix-at-risk-of-preterm-delivery
#17
Laura Karis Allen, Jane Schulz, Catherine Flood, Sue Ross, Kentia Naud
OBJECTIVE: A paucity of effective interventions exists for the prevention of preterm birth (PTB). Renewed interest has focused on cervical pessaries, which have the benefits of being inexpensive, nonsurgical, and easily inserted and removed. In this study, we aim to describe our experience with this device in a Canadian tertiary care centre. Primary outcomes were rates of spontaneous or iatrogenic PTB before 37, 34, and 28 weeks gestation in pregnancies complicated by short cervix treated with cervical pessary...
August 16, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28822627/do-anterior-catheterizable-urinary-channels-have-fewer-complications-than-posterior-channels-an-international-cohort-study
#18
K M Szymanski, P-J Lopez, J P Corbetta, F Reed, J Ruiz, Y Pullin, S Weller, R Zubieta, R C Rink, M P Cain
OBJECTIVE: Appendicovesicostomy (APV) and Monti ileovesicostomy (Monti) are durable catheterizable channels. While subfascial revision rates vary by channel type, a channel implanted in the anterior (vs posterior) aspect of the bladder may have a lower subfascial revision risk, due to decreased channel mobility and better fascial fixation. The present study aimed to compare long-term durability of anteriorly compared to posteriorly implanted APV and Monti channels in a large international cohort...
August 2, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28822623/high-resolution-computed-tomography-features-distinguishing-benign-and-malignant-lesions-manifesting-as-persistent-solitary-subsolid-nodules
#19
Wenjia Yang, Yifeng Sun, Wentao Fang, Fangfei Qian, Jianding Ye, Qunhui Chen, Yifeng Jiang, Keke Yu, Baohui Han
INTRODUCTION: We retrospectively investigated the high-resolution computed tomography features that distinguish benign lesions (BLs) from malignant lesions (MLs) appearing as persistent solitary subsolid nodules (SSNs). MATERIALS AND METHODS: In 2015, the data from patients treated in our department with persistent solitary SSNs 5 to 30 mm in size were analyzed retrospectively. The demographic data and HRCT findings were analyzed and compared between those with BLs and MLs...
June 8, 2017: Clinical Lung Cancer
https://www.readbyqxmd.com/read/28822586/intravenous-mannitol-versus-placebo-during-partial-nephrectomy-in-patients-with-normal-kidney-function-a-double-blind-clinically-integrated-randomized-trial
#20
Massimiliano Spaliviero, Nicholas E Power, Katie S Murray, Daniel D Sjoberg, Nicole E Benfante, Melanie L Bernstein, James Wren, Paul Russo, Jonathan A Coleman
BACKGROUND: Mannitol is currently used as a renal protective agent to mitigate the effects of renal ischemia during nephron-sparing surgery (NSS). This routine practice lacks rigorous methodological study. OBJECTIVE: To assess the effect on renal function outcomes after surgery of mannitol infusion prior to renal ischemia during NSS. DESIGN, SETTING, PARTICIPANTS: This prospective, randomized, placebo-controlled, double-blind trial included 199 patients with a preoperative estimated glomerular filtration rate (eGFR) >45ml/min/1...
August 16, 2017: European Urology
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