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https://www.readbyqxmd.com/read/29353231/the-preterm-heart-in-childhood-left-ventricular-structure-geometry-and-function-assessed-by-echocardiography-in-6-year-old-survivors-of-periviable-births
#1
Lilly-Ann Mohlkert, Jenny Hallberg, Olof Broberg, Annika Rydberg, Cecilia Pegelow Halvorsen, Petru Liuba, Vineta Fellman, Magnus Domellöf, Gunnar Sjöberg, Mikael Norman
BACKGROUND: Preterm birth has been associated with increased risk of cardiovascular morbidity in adult life. We evaluated whether preterm birth is associated with deviating cardiac structure and function before school start. METHODS AND RESULTS: In total, 176 children aged 6 years and born extremely preterm (EXPT; gestational age of 22-26 weeks) and 134 children born at term (control [CTRL]) were studied. We used echocardiography to assess left heart dimensions, geometry, and functions...
January 20, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29352590/allergic-proctocolitis-is-a-risk-factor-for-functional-gastrointestinal-disorders-in-children
#2
Giovanni Di Nardo, Cesare Cremon, Simone Frediani, Sandra Lucarelli, Maria Pia Villa, Vincenzo Stanghellini, Giuseppe La Torre, Luigi Martemucci, Giovanni Barbara
OBJECTIVE: To test the hypothesis that allergic proctocolitis, a cause of self-limiting rectal bleeding in infants, can predispose to the development of functional gastrointestinal disorders (FGIDs) later in childhood. STUDY DESIGN: We studied a cohort of 80 consecutive patients diagnosed with allergic proctocolitis. Their sibling or matched children presenting to the same hospital for minor trauma served as controls. Parents of the patients with allergic proctocolitis and controls participated in a telephone interview every 12 months until the child was at least 4 years old...
January 15, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29352102/teenage-onset-progressive-myoclonic-epilepsy-due-to-a-familial-c9orf72-repeat-expansion
#3
Jelle van den Ameele, Ivana Jedlickova, Anna Pristoupilova, Anne Sieben, Sara Van Mossevelde, Chantal Ceuterick-de Groote, Helena Hůlková, Radoslav Matej, Alfred Meurs, Christine Van Broeckhoven, Samuel F Berkovic, Patrick Santens, Stanislav Kmoch, Bart Dermaut
BACKGROUND: The progressive myoclonic epilepsies (PME) are a heterogeneous group of disorders in which a specific diagnosis cannot be made in a subset of patients, despite exhaustive investigation. C9orf72 repeat expansions are emerging as an important causal factor in several adult-onset neurodegenerative disorders, in particular frontotemporal lobar degeneration and amyotrophic lateral sclerosis. An association with PME has not been reported previously. OBJECTIVE: To identify the causative mutation in a Belgian family where the proband had genetically unexplained PME...
January 19, 2018: Neurology
https://www.readbyqxmd.com/read/29349924/parental-supervision-for-their-children-s-toothbrushing-mediating-effects-of-planning-self-efficacy-and-action-control
#4
Kyra Hamilton, Stephen Cornish, Aaron Kirkpatrick, Jeroen Kroon, Ralf Schwarzer
OBJECTIVES: With 60-90% of children worldwide reportedly experiencing dental caries, poor oral health in the younger years is a major public health issue. As parents are important to children's oral hygiene practices, we examined the key self-regulatory behaviours of parents for supervising their children's toothbrushing using the health action process approach. DESIGN AND METHOD: Participants (N = 281, 197 mothers) comprised Australian parents of 2- to 5-year-olds...
January 18, 2018: British Journal of Health Psychology
https://www.readbyqxmd.com/read/29349628/serum-total-magnesium-level-and-its-correlation-with-symptom-control-in-children-with-mild-persistent-asthma
#5
Pavani Chitamanni, Venkatesh Chandrasekaran, Soundravally Rajendiran
OBJECTIVES: To determine the prevalence of hypomagnesemia in children with mild persistent asthma and to correlate the serum magnesium levels with symptom control in the above children. METHODS: It was a cross sectional study carried out from 1st April 2015 to 31st July 2016 at the department of Pediatrics, JIPMER Hospital. Participants included six to 12-y-old children with mild persistent asthma registered at childhood asthma clinic. Pulmonary function tests were done in all children using Care fusion Jaeger spirometer...
January 19, 2018: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29349262/mothers-labor-market-choices-and-child-development-outcomes-in-chile
#6
Sarah A Reynolds, Lia C H Fernald, Jere R Behrman
This paper examines associations between labor market participation of Chilean mothers and the cognitive, language, and socio-economic development of their children. Using a nationally-representative sample of 3-year-old children, we test if mothers' work intensity in the two previous years is associated with child development outcomes; data were collected in 2010 when children were one year old, and again in 2012, when they were three years old. We find that children who were three years old with mothers who worked for higher fractions of their children's lives in the previous two years perform significantly better on all tests (cognitive, language, socio-emotional) than children whose mothers had worked less, while controlling for baseline test performance...
December 2017: SSM—Population Health
https://www.readbyqxmd.com/read/29349204/validity-of-a-scale-of-neighbourhood-informal-social-control-relevant-to-pre-schoolers-physical-activity-a-cross-sectional-study
#7
Ester Cerin, Yi Nam Suen, Anthony Barnett, Wendy Y J Huang, Robin R Mellecker
Childhood physical activity (PA) is important for health across the lifespan. Time pre-schoolers spend outdoors, which has been associated with more PA, is likely influenced by parents' perception of neighbourhood informal social control relevant to pre-schoolers' PA, defined as the willingness of neighbours to intervene to ensure social order and a safe community environment for young children's active play. To advance measurement of this construct, we assessed factorial and construct validities of the PA-related neighbourhood informal social control scale for parents of pre-schoolers (PANISC-PP)...
December 2017: SSM—Population Health
https://www.readbyqxmd.com/read/29348906/an-ank1-ivs3-2a-c-mutation-causes-exon-4-skipping-in-two-patients-from-a-chinese-family-with-hereditary-spherocytosis
#8
Xiong Wang, Liyan Mao, Na Shen, Jing Peng, Yaowu Zhu, Qun Hu, Yanjun Lu
Hereditary spherocytosis (HS) is a congenital hemolytic anemia that affects the cell membrane of red blood cells and is characterized by the presence of spherical-shaped erythrocytes in the peripheral blood film. The clinical manifestation of HS ranges from asymptomatic to severe cases that require transfusion during early childhood. HS is caused by mutations in red blood cell membrane protein encoding genes, including ANK1, EPB42, SLC4A1, SPTA1, and SPTB. Mutations of the ANK1 gene account for 75% of all HS cases, and these particular mutations are typically inherited in an autosomal dominant manner...
December 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/29348602/the-ten-year-evolutionary-trajectory-of-a-highly-recurrent-paediatric-high-grade-neuroepithelial-tumour-with-mn1-bend2-fusion
#9
Anna Burford, Alan Mackay, Sergey Popov, Maria Vinci, Diana Carvalho, Matthew Clarke, Elisa Izquierdo, Aimee Avery, Thomas S Jacques, Wendy J Ingram, Andrew S Moore, Kieran Frawley, Timothy E Hassall, Thomas Robertson, Chris Jones
Astroblastomas are rare brain tumours which predominate in children and young adults, and have a controversial claim as a distinct entity, with no established WHO grade. Reports suggest a better outcome than high grade gliomas, though they frequently recur. Recently, they have been described to overlap with a newly-discovered group of tumours described as'high grade neuroepithelial tumour with MN1 alteration' (CNS HGNET-MN1), defined by global methylation patterns and strongly associated with gene fusions targeting MN1...
January 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29347942/infant-and-child-mortality-in-relation-to-malaria-transmission-in-kemri-cdc-hdss-western-kenya-validation-of-verbal-autopsy
#10
Nyaguara O Amek, Annemieke Van Eijk, Kim A Lindblade, Mary Hamel, Nabie Bayoh, John Gimnig, Kayla F Laserson, Laurence Slutsker, Thomas Smith, Penelope Vounatsou
BACKGROUND: Malaria transmission reduction is a goal of many malaria control programmes. Little is known of how much mortality can be reduced by specific reductions in transmission. Verbal autopsy (VA) is widely used for estimating malaria specific mortality rates, but does not reliably distinguish malaria from other febrile illnesses. Overall malaria attributable mortality includes both direct and indirect deaths. It is unclear what proportion of the deaths averted by reducing malaria transmission are classified as malaria in VA...
January 18, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29345507/ovarian-tissue-cryopreservation-in-young-females-through-the-oncofertility-consortium-s-national-physicians-cooperative
#11
Austin G Armstrong, Bruce F Kimler, Brigid M Smith, Teresa K Woodruff, Mary Ellen Pavone, Francesca E Duncan
AIM: To characterize the clinical indications of females (<15 years old) undergoing ovarian tissue cryopreservation (OTC) through the Oncofertility Consortium's National Physicians Cooperative (OC-NPC). PATIENTS & METHODS: The clinical indications of 114 females who underwent OTC were classified, and their incidence was compared with childhood cancer databases. RESULTS: Leukemias/myeloproliferative diseases/myelodysplastic diseases and hemoglobinopathies were the most prevalent oncologic and nononcologic indications for OTC, respectively...
January 18, 2018: Future Oncology
https://www.readbyqxmd.com/read/29344986/evaluation-of-bowel-function-in-healthy-children-untreated-constipation-is-common
#12
Helena Lindgren, Malin Carvalho Nejstgaard, Martin Salö, Pernilla Stenström
AIM: We evaluated bowel function in healthy children with regard to gender and age. METHODS: The study was carried out in 2016 at a tertiary children's hospital. Healthy children aged 3.5-15 years old who were admitted to the hospital, siblings to patients, or offspring of staff members were included. Validated self-report questionnaires, and internally developed questions regarding obstructive outlet- and gas-related symptoms were used. RESULTS: A total of 310 participants (50% girls) were included, which corresponded to a 94% answer frequency...
January 18, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29344561/self-expandable-metal-stent-placement-in-a-child-for-treatment-of-achalasia-after-failed-heller-myotomy
#13
Roberto Gugig, Guillermo Muñoz Jurado, Clifton Huang, Roberto Oleas, Carlos Robles-Medranda
Background and study aims  Childhood achalasia treatment remains inconclusive. What is next after myotomy failure? Repeated pneumatic-dilation put patients at greater risk of perforation with possible symptom recurrence. We report on a 12-year-old patient with a 1-year history of achalasia whom underwent Heller myotomy with fundoplication and recurred with symptoms 1 week after surgery. Pneumatic dilatation was considered but not done because of the risk of esophageal perforation. The decision was made to place a fully covered self-expanding metallic stent (FC-SEMS) for 3 months, which resolved the stenosis as confirmed by esophagram...
January 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29344035/hypercalcaemic-pancreatitis-adrenal-insufficiency-autoimmune-thyroiditis-and-diabetes-mellitus-in-a-girl-with-probable-sarcoidosis
#14
Devi Dayal, Olivia Pepper, Renuka Ramakrishnan, Eileen Baildam, Poonam Dharmaraj, Gavin Cleary, Liza McCann, Clare Pain, Senthil Senniappan
Introduction: Sarcoidosis is a multisystemic granulomatous disease with diverse and often non-specific symptoms during childhood. The clinical manifestations sometimes include endocrinopathies related to sarcoid infiltration of various endocrine organs, but more commonly due to the associated autoimmune endocrine disorders. There are only a few reports of multiple autoimmune and non-autoimmune endocrine problems occurring simultaneously in patients with sarcoidosis. We report a girl with probable sarcoidosis who also had Hashimoto's thyroiditis, Type 1 diabetes (T1D) and secondary adrenal insufficiency...
October 2017: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29342995/-pediatric-myeloid-neoplasms-associated-with-eosinophilia-and-platelet-derived-growth-factor-receptor-beta-gene-rearrangement-a-case-report-and-literature-review
#15
X Y Zhang, T F Liu, C W Li, Q H Li, X F Zhu
Objective: To investigate the clinical features and therapeutic strategies of childhood myeloid neoplasms associated with eosinophilia and platelet-derived growth factor receptor beta (PDGFRB) gene rearrangement. Methods: Clinical data of myeloid neoplasms associated with eosinophilia and t (1;5) (q21;q33) chromosomal translocation of PDGFRB gene rearrangement in a child hospitalized in Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences on May 2015 was collected and analyzed...
January 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29341214/cue-reactivity-habituation-and-eating-in-the-absence-of-hunger-in-children-with-loss-of-control-eating-and-attention-deficit-hyperactivity-disorder
#16
Anja Hilbert, Susanne Kurz, Daniela Dremmel, Susann Weihrauch Blüher, Simone Munsch, Ricarda Schmidt
OBJECTIVE: Childhood loss of control (LOC) eating and attention-deficit/hyperactivity disorder (ADHD) are highly comorbid conditions and present with disordered eating behaviors, such as overeating. This study sought to delineate shared and specific abnormalities in physiological, cognitive-motivational, and behavioral components of food-specific impulsivity in children with LOC eating and ADHD. Specifically, children's reactivity and habituation to food and eating in the absence of hunger were examined...
January 17, 2018: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/29339565/a-home-visiting-parenting-program-and-child-obesity-a-randomized-trial
#17
Monica Roosa Ordway, Lois S Sadler, Margaret L Holland, Arietta Slade, Nancy Close, Linda C Mayes
BACKGROUND: Young children living in historically marginalized families are at risk for becoming adolescents with obesity and subsequently adults with increased obesity-related morbidities. These risks are particularly acute for Hispanic children. We hypothesized that the prevention-focused, socioecological approach of the "Minding the Baby" (MTB) home visiting program might decrease the rate of childhood overweight and obesity early in life. METHODS: This study is a prospective longitudinal cohort study in which we include data collected during 2 phases of the MTB randomized controlled trial...
January 16, 2018: Pediatrics
https://www.readbyqxmd.com/read/29338905/posterior-reversible-encephalopathy-syndrome-a-rare-childhood-case-with-unconsciousness
#18
Akira Komori, Daisuke Mizu, Koichi Ariyoshi
BACKGROUND: Posterior reversible encephalopathy syndrome (PRES) is a condition characterized by seizures, altered consciousness, visual disturbances, and headache. Characteristic findings on neuroimaging include cerebral edema, typically involving the parieto-occipital white matter. PRES has been associated with hypertension, autoimmune disease, and Henoch-Schölein purpura (HSP), but few cases have been reported, and fewer cases of PRES have been reported in children. CASE REPORT: We report the case of a 4-year-old girl who presented with blindness and semi-consciousness...
January 12, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29338753/examining-within-and-across-day-relationships-between-transient-and-chronic-stress-and-parent-food-related-parenting-practices-in-a-racially-ethnically-diverse-and-immigrant-population-stress-types-and-food-related-parenting-practices
#19
Jerica M Berge, Allan Tate, Amanda Trofholz, Angela Fertig, Scott Crow, Dianne Neumark-Sztainer, Michael Miner
BACKGROUND: Although prior research suggests that stress may play a role in parent's use of food-related parenting practices, it is unclear whether certain types of stress (e.g., transient, chronic) result in different food-related parenting practices. Identifying whether and how transient (i.e., momentary; parent/child conflict) and chronic (i.e., long-term; unemployment >6 months) sources of stress are related to parent food-related parenting practices is important with regard to childhood obesity...
January 16, 2018: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/29338155/association-between-caregiver-exposure-to-toxics-during-pregnancy-and-childhood-onset-asthma-a-case-control-study
#20
Souheil Hallit, Chantal Raherison, Mirna Waked, Pascale Salameh
The aim of this study was to evaluate the associations between caregiver-reported use of medications, alcohol, cigarette and/or waterpipe (WP), and exposure to pesticides/detergents during pregnancy with childhood-onset asthma. The study design consisted of a case-control study, conducted between December 2015 and April 2016, recruited 1503 children, aged between 3-16 years old. A questionnaire assessed the sociodemographic characteristics (age, gender, education level of both parents), the family history of asthma, and other known risk factors of asthma (heating system at home, child history of recurrent otitis, humidity in the house, child went to a daycare, smoking and drinking alcohol during pregnancy, exposure to pesticides and detergents)...
December 2017: Iranian Journal of Allergy, Asthma, and Immunology
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