Macarena Ortiz, Francisca Sánchez, Daniela Álvarez, Cristian Flores, Francisca Salas-Pérez, Rodrigo Valenzuela, Claudette Cantin, Andrea Leiva, Nicolás Crisosto, Manuel Maliqueo
Maternal obesity and the imbalance in linoleic acid (C18:2 n-6, LA) and alpha-linolenic acid (C18:3 n-3, ALA) levels are related with hepatic disturbances in the offspring. However, whether these alterations are present during fetal life is not well understood. Obese and normal weight pregnant women were recruited to determine fatty acids (FAs) consumption, FAs profile (in maternal erythrocytes, placenta and neonatal very low-density lipoproteins VLDL) and biomarkers of fetal liver function, such as gamma-glutamyl transferase (GGT), alpha-fetoprotein (AFP) and albumin, in umbilical cord blood...
March 2023: Prostaglandins, Leukotrienes, and Essential Fatty Acids