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https://www.readbyqxmd.com/read/29222741/exploratory-study-of-barriers-to-successful-office-contacts-for-attention-deficit-hyperactivity-disorder
#1
Jayde T Hooven, Benjamin N Fogel, James G Waxmonsky, Deepa L Sekhar
The American Academy of Pediatrics published attention deficit hyperactivity disorder (ADHD) guidelines, but significant variability exists in care. This exploratory study aimed to understand barriers to compliance with primary care office contacts for ADHD medication management. The study was conducted at a single academic medical center via retrospective chart review between 6/1/15 and 5/31/16 in combination with telephone interviews. Participants included 306 children 6-12 years old with an ADHD-related ICD-9/ICD-10 diagnosis...
December 8, 2017: Attention Deficit and Hyperactivity Disorders
https://www.readbyqxmd.com/read/29222634/what-is-the-level-of-evidence-for-the-use-of-currently-available-technologies-in-facilitating-the-self-management-of-difficulties-associated-with-adhd-in-children-and-young-people-a-systematic-review
#2
REVIEW
Lauren Powell, Jack Parker, Valerie Harpin
A number of technologies to help self-manage attention deficit hyperactivity disorder (ADHD) in children and young people (YP) have been developed. This review will assess the level of evidence for the use of such technologies. The review was undertaken in accordance with the general principles recommended in the Preferred Reporting Items for Systematic Reviews and Meta-Analysis. 7545 studies were screened. Fourteen studies of technology that aim to self-manage difficulties associated with ADHD in children and YP were included...
December 8, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29222591/dementia-with-lewy-bodies-and-parkinson-s-disease-dementia-current-concepts-and-controversies
#3
REVIEW
Kurt A Jellinger
Dementia with Lewy bodies (DLB) and Parkinson's disease-dementia (PDD), although sharing many clinical, neurochemical and morphological features, according to DSM-5, are two entities of major neurocognitive disorders with Lewy bodies of unknown etiology. Despite considerable clinical overlap, their diagnosis is based on an arbitrary distinction between the time of onset of motor and cognitive symptoms: dementia often preceding parkinsonism in DLB and onset of cognitive impairment after onset of motor symptoms in PDD...
December 8, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/29221785/attention-deficit-hyperactivity-disorder-symptom-severity-and-sleep-problems-in-adult-participants-of-the-netherlands-sleep-registry
#4
Suzan W N Vogel, Denise Bijlenga, Jeroen S Benjamins, Aartjan T F Beekman, J J Sandra Kooij, Eus J W Van Someren
BACKGROUND: We examined whether current overall attention deficit hyperactivity disorder (ADHD), inattention, or hyperactivity symptom severities are associated with the current presence and persistent history of sleep problems. METHODS: N = 942 participants of the Netherlands Sleep Registry filled out online several validated questionnaires. Regression analyses were performed to assess the association between (1) current overall ADHD symptom severity and the current presence of sleep problems, (2) current ADHD symptom-severity groups and the persistent history of sleep problems, and (3) current inattention or hyperactivity symptom severities and the current presence of sleep problems...
December 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29220204/attention-deficit-hyperactivity-disorder-adhd-controversy-developmental-mechanisms-and-multiple-levels-of-analysis
#5
Stephen P Hinshaw
Controversy abounds regarding the symptom dimensions of attention problems, impulsivity, and hyperactivity, developmentally extreme and impairing levels of which compose the diagnostic category of attention deficit hyperactivity disorder (ADHD). I highlight causal factors, underlying mechanisms, developmental manifestations, and female manifestations of ADHD, integrating the psychobiological underpinnings of this syndrome with contextual factors related to its clinical presentation, impairments, and soaring increases in diagnosed prevalence...
December 8, 2017: Annual Review of Clinical Psychology
https://www.readbyqxmd.com/read/29218791/a-novel-approach-to-training-attention-and-gaze-in-asd-a-feasibility-and-efficacy-pilot-study
#6
Leanne Chukoskie, Marissa Westerfield, Jeanne Townsend
In addition to the social, communicative and behavioral symptoms that define the disorder, individuals with ASD have difficulty re-orienting attention quickly and accurately. Similarly, fast re-orienting saccadic eye movements are also inaccurate and more variable in both endpoint and timing. Atypical gaze and attention are among the earliest symptoms observed in ASD. Disruption of these foundation skills critically affects development of higher level cognitive and social behavior. We propose that interventions aimed at these early deficits that support social and cognitive skills will be broadly effective...
December 8, 2017: Developmental Neurobiology
https://www.readbyqxmd.com/read/29216607/frequency-of-risk-factors-and-coexisting-abnormalities-in-a-population-of-egyptian-children-with-autism-spectrum-disorder
#7
Nagwa Abdel Meguid, Neveen Hassan Nashaat, Heba S Hashem, Mai M Khalil
BACKGROUND: Many risk factors interact together during the critical period of development and govern the future phenotype of autism spectrum disorder (ASD). Furthermore, co-occurring abnormalities among individuals with ASD vary a lot so as their abilities. AIM OF WORK: To investigate possible risk factors and to determine the prevalence of coexisting abnormalities in a sample of Egyptian ASD children and their influence on the severity and their communication performance...
December 1, 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29215904/practice-procedures-in-models-of-primary-care-collaboration-for-children-with-adhd
#8
Jessica A Moore, Kathryn Karch, Valeriia Sherina, Aubree Guiffre, Sandra Jee, Lynn C Garfunkel
INTRODUCTION: With nationwide movement toward an integrated medical home, evidence to support, compare, and specify effective models for collaboration between primary care and behavioral health professionals is essential. This study compared 2 models of primary care with behavioral health integration on American Academy of Pediatrics guideline adherence for attention-deficit/hyperactivity disorder (ADHD) assessment and treatment. METHOD: We conducted a retrospective chart review of a random sample of children aged 6-13 years, seen for ADHD services in 2 primary care offices, 1 fully integrated model and 1 co-located service only model, comparing ADHD assessment and treatment practices...
December 7, 2017: Families, Systems & Health: the Journal of Collaborative Family Healthcare
https://www.readbyqxmd.com/read/29215804/cognitive-function-and-neuropsychological-comorbidities-in-children-with-newly-diagnosed-idiopathic-epilepsy
#9
Seung Yun Lee, Jang Ho Park, Sin Jae Park, Yangho Kim, Kyung Yeon Lee
BACKGROUND: In this study, we aimed to identify cognitive function and neuropsychological comorbidities in children with newly diagnosed idiopathic epilepsy. METHODS: We retrospectively reviewed the records of 97 antiepileptic drug-naïve children (9.7 ± 2.9 years; 54 males and 43 females) with newly diagnosed idiopathic epilepsy, all of whom underwent a neuropsychological battery. The battery consisted of the Korean Wechsler Intelligence Scale, Attention Deficit Hyperactivity Disorder (ADHD) Rating Scale, ADHD Diagnostic System, Children's Depression Inventory, and State-Trait Anxiety Inventory for Children...
January 15, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29214840/bifactor-models-of-attention-deficit-hyperactivity-symptomatology-in-adolescents-criterion-validity-and-implications-for-clinical-practice
#10
Michael T Willoughby, Gregory A Fabiano, Nicole K Schatz, Rebecca K Vujnovic, Karen L Morris
This study evaluated the fit and criterion validity of a bifactor model for 18 DSM-IV attention deficit/hyperactivity disorder (ADHD) symptoms, along with nine supplementary symptoms that represented the manifestation of inattention and hyperactivity-impulsivity in adolescence and early adulthood. Participants included N = 172 adolescents who were diagnosed with combined type ADHD and who were enrolled in a treatment study. A bifactor model provided reasonably good fit to combined parent- and teacher-reported DSM symptoms and supplemental items at baseline prior to treatment...
March 1, 2017: Assessment
https://www.readbyqxmd.com/read/29214372/a-review-of-the-clinical-utility-of-systematic-behavioral-observations-in-attention-deficit-hyperactivity-disorder-adhd
#11
Franziska Minder, Agnieszka Zuberer, Daniel Brandeis, Renate Drechsler
This review evaluates the clinical utility of tools for systematic behavioral observation in different settings for children and adolescents with ADHD. A comprehensive search yielded 135 relevant results since 1990. Observations from naturalistic settings were grouped into observations of classroom behavior (n = 58) and of social interactions (n = 25). Laboratory observations were subdivided into four contexts: independent play (n = 9), test session (n = 27), parent interaction (n = 11), and peer interaction (n = 5)...
December 6, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/29214137/speak-up-increasing-conversational-volume-in-a-child-with-autism-spectrum-disorder
#12
Leigh Edgerton, Byron Wine
Deficits in social interactions are a hallmark of autism spectrum disorder. This study examined one relatively uncommon aspect of social interactions that has not received much attention from the literature: appropriate conversational volume. Conversational speech volume was measured using a commercially available application, and a package intervention was developed that consisted of feedback from the voice measuring application, signaling from a wrist bracelet, and differential reinforcement. The intervention was evaluated in an ABAB design and speaking at conversational volume was significantly increased when the intervention was in place and in probe conditions...
December 2017: Behavior Analysis in Practice
https://www.readbyqxmd.com/read/29212874/the-na-k-h-exchanger-nhx1-controls-multivesicular-body-vacuolar-lysosome-fusion
#13
Mahmoud Abdul Karim, Christopher Leonard Brett
Loss-of-function mutations in human endosomal Na+(K+)/H+ Exchangers (NHEs) NHE6 and NHE9 are implicated in neurological disorders including Christianson Syndrome, autism and attention deficit and hyperactivity disorder (ADHD). These mutations disrupt retention of surface receptors within neurons and glial cells by affecting their delivery to lysosomes for degradation. However, the molecular basis of how these endosomal NHEs control endocytic trafficking is unclear. Using Saccharomyces cerevisiae as a model, we conducted cell-free organelle fusion assays to show that transport activity of the orthologous endosomal NHE Nhx1 is important for multivesicular body (MVB)-vacuolar lysosome fusion, the last step of endocytosis required for surface protein degradation...
December 6, 2017: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/29211967/efficacy-and-safety-of-amphetamine-extended-release-oral-suspension-in-children-with-attention-deficit-hyperactivity-disorder
#14
Ann C Childress, Sharon B Wigal, Matthew N Brams, John M Turnbow, Yulia Pincus, Heidi W Belden, Sally A Berry
OBJECTIVES: To determine the efficacy and safety of amphetamine extended-release oral suspension (AMPH EROS) in the treatment of attention-deficit/hyperactivity disorder (ADHD) in a dose-optimized, randomized, double-blind, parallel-group study. METHODS: Boys and girls aged 6 to 12 years diagnosed with ADHD were enrolled. During a 5-week, open-label, dose-optimization phase, patients began treatment with 2.5 or 5 mg/day of AMPH EROS; doses were titrated until an optimal dose (maximum 20 mg/day) was reached...
December 6, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29209833/fine-motor-ability-and-psychiatric-disorders-in-youth
#15
Lorenna Sena Teixeira Mendes, Gisele Gus Manfro, Ary Gadelha, Pedro Mario Pan, Rodrigo Affonseca Bressan, Luis Augusto Rohde, Giovanni Abrahão Salum
Impaired fine motor ability has been linked to several domains of psychopathology. However, studies validating the specificity of this association among several categorical psychiatric disorders are still needed. The aim of this study was to assess differences in fine motor ability performance among four non-overlapping groups of psychiatric disorders and a group of typical developing comparisons (TDC). Our sample consisted of 2035 subjects aged 6-14-year-old. Diagnoses of psychiatric disorders were performed with the Development and Well-Being Assessment (DAWBA)...
December 5, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29209386/medical-and-psychiatric-comorbidities-in-korean-children-and-adolescents-with-attention-deficit-hyperactivity-disorder
#16
Kee Jeong Park, Jung Sun Lee, Hyo-Won Kim
Objective: Attention-deficit/hyperactivity disorder (ADHD) is associated with a high rate of comorbid disorders. We aimed to investigate the medical and psychiatric comorbidities of Korean children and adolescents with ADHD. Methods: Data were obtained from Korean National Health Insurance Review and Assessment Service-National Patient Sample (HI-RA-NPS) for 2011. We included 2,140 (mean age, 10.9±3.1 years; boys, 1,710) and 219,410 (non-ADHD; mean age, 12.4±3...
November 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/29209385/the-role-of-uncontrolled-eating-and-screen-time-in-the-link-of-attention-deficit-hyperactivity-disorder-with-weight-in-late-childhood
#17
Joung-Sook Ahn, Seongho Min, Min-Hyuk Kim
Objective: The aim of this study was to examine the mediating roles of uncontrolled eating and sedentary behaviours in the link of attention deficit hyperactivity disorder (ADHD) and weight. Methods: A total of 352 children in fifth and sixth grade participated in the present study by completing the self-rated Three-Factor Eating Questionnaire and Children of Alcoholics Screening Test during regular classes. An additional questionnaire completed by their parents provided information about the children's ADHD and emotional symptoms, sedentary behaviour based on screen time, and parental variables...
November 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/29209238/disrupted-control-related-functional-brain-networks-in-drug-naive-children-with-attention-deficit-hyperactivity-disorder
#18
Jiejie Tao, Xueyan Jiang, Xin Wang, Huiru Liu, Andan Qian, Chuang Yang, Hong Chen, Jiance Li, Qiong Ye, Jinhui Wang, Meihao Wang
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disease featuring executive control deficits as a prominent neuropsychological trait. Executive functions are implicated in multiple sub-networks of the brain; however, few studies examine these sub-networks as a whole in ADHD. By combining resting-state functional MRI and graph-based approaches, we systematically investigated functional connectivity patterns among four control-related networks, including the frontoparietal network (FPN), cingulo-opercular network, cerebellar network, and default mode network (DMN), in 46 drug-naive children with ADHD and 31 age-, gender-, and intelligence quotient-matched healthy controls (HCs)...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29209170/noradrenaline-modulates-the-membrane-potential-and-holding-current-of-medial-prefrontal-cortex-pyramidal-neurons-via-%C3%AE-1-adrenergic-receptors-and-hcn-channels
#19
Katarzyna Grzelka, Przemysław Kurowski, Maciej Gawlak, Paweł Szulczyk
The medial prefrontal cortex (mPFC) receives dense noradrenergic projections from the locus coeruleus. Adrenergic innervation of mPFC pyramidal neurons plays an essential role in both physiology (control of memory formation, attention, working memory, and cognitive behavior) and pathophysiology (attention deficit hyperactivity disorder, posttraumatic stress disorder, cognitive deterioration after traumatic brain injury, behavioral changes related to addiction, Alzheimer's disease and depression). The aim of this study was to elucidate the mechanism responsible for adrenergic receptor-mediated control of the resting membrane potential in layer V mPFC pyramidal neurons...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29207797/audit-of-organic-acidurias-from-a-single-centre-clinical-and-metabolic-profile-at-presentation-with-long-term-outcome
#20
Seema Pavaman Sindgikar, Krithika Damodar Shenoy, Nutan Kamath, Rathika Shenoy
Introduction: Organic Acidurias (OA) accounts between 10% and 40% of confirmed Inborn Errors of Metabolism (IEM) in India. With prompt recognition and management, better survival but adverse neurodevelopmental outcome is reported. Aim: To study the clinical and metabolic presentation, management with immediate and long term outcome of symptomatic children with confirmed OA. Materials and Methods: Hospital based study of symptomatic children diagnosed to have OA between 2003 and 2009 and the survivors followed up over next five years...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
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