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https://www.readbyqxmd.com/read/29054088/the-interactions-among-organophosphate-pesticide-exposure-oxidative-stress-and-genetic-polymorphisms-of-dopamine-receptor-d4-increase-the-risk-of-attention-deficit-hyperactivity-disorder-in-children
#1
Chia-Huang Chang, Ching-Jung Yu, Jung-Chieh Du, Hsien-Chih Chiou, Hsin-Chang Chen, Winnie Yang, Ming-Yi Chung, Ying-Sheue Chen, Betau Hwang, I-Fang Mao, Mei-Lien Chen
OBJECTIVE: The aim of this study was to clarify the association between organophosphate pesticides (OPs) and attention-deficit/hyperactivity disorder (ADHD) related to oxidative stress and genetic polymorphisms. METHODS: This case-control study enrolled 93 children with ADHD and 112 control children in north Taiwan. Six dialkyl phosphate (DAP) metabolites of OPs and oxidative stress biomarkers were analyzed. Polymorphisms of the dopamine receptor D4 gene (DRD4) were identified...
October 17, 2017: Environmental Research
https://www.readbyqxmd.com/read/29053637/progress-in-genetic-studies-of-tourette-s-syndrome
#2
REVIEW
Yanjie Qi, Yi Zheng, Zhanjiang Li, Lan Xiong
Tourette's Syndrome (TS) is a complex disorder characterized by repetitive, sudden, and involuntary movements or vocalizations, called tics. Tics usually appear in childhood, and their severity varies over time. In addition to frequent tics, people with TS are at risk for associated problems including attention deficit hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), anxiety, depression, and problems with sleep. TS occurs in most populations and ethnic groups worldwide, and it is more common in males than in females...
October 20, 2017: Brain Sciences
https://www.readbyqxmd.com/read/29052846/improvements-of-adolescent-psychopathology-after-insomnia-treatment-results-from-a-randomized-controlled-trial-over-1%C3%A2-year
#3
Eduard J de Bruin, Susan M Bögels, Frans J Oort, Anne Marie Meijer
BACKGROUND: Adolescent insomnia can be treated effectively with cognitive behavioural therapy for insomnia (CBTI). However, little is known about effects of CBTI on psychopathology in adolescents. This study aimed to investigate whether (a) CBTI improves psychopathology in Internet- (IT) and face-to-face group treatment (GT) compared to waitlist (WL), (b) improvement in psychopathology can be attributed to reduced insomnia, (c) improvement in psychopathology remains stable for up to 1 year...
October 20, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29052741/-regional-differences-of-adhd-diagnosis-rates-in-health-insurance-data-from-2005-to-2015-methodological-considerations-and-results
#4
REVIEW
Thomas G Grobe
BACKGROUND AND OBJECTIVES: Attention deficit hyperactivity disorders (ADHD) are among the most common mental disorders in children and adolescents. For a number of years there has been evidence of regional differences in Germany. This article provides current results on the frequency of diagnosis and treatment and also discusses methodological aspects. MATERIALS AND METHODS: The analysis is based on routine data of a statutory health insurance company including annual diagnoses and drug prescriptions from 2005 to 2015 of at least 1...
October 20, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/29052617/adhd-smoking-withdrawal-and-inhibitory-control-results-of-a-neuroimaging-study-with-methylphenidate-challenge
#5
Maggie M Sweitzer, Scott H Kollins, Rachel V Kozink, Matt Hallyburton, Joseph English, Merideth A Addicott, Jason A Oliver, F Joseph McClernon
Smoking withdrawal negatively impacts inhibitory control, and these effects are greater for smokers with pre-existing attention problems, such as attention deficit/hyperactivity disorder (ADHD). The current study preliminarily evaluated changes in inhibitory control-related behavior and brain activation during smoking withdrawal among smokers with ADHD. Moreover, we investigated the role of catecholamine transmission in these changes by examining effects of 40 mg methylphenidate (MPH) administration. Adult daily smokers with (n=17) and without (n=20) ADHD completed fMRI scanning under each of three conditions: (a) smoking as usual+placebo; (b) 24 hr smoking abstinence+placebo and (c) 24 hr smoking abstinence+MPH...
October 20, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29052031/do-pharmaceuticals-improve-driving-in-individuals-with-adhd-a-review-of-the-literature-and-evidence-for-clinical-practice
#6
REVIEW
Craig B H Surman, Ronna Fried, Lauren Rhodewalt, Heidi Boland
Attention-deficit/hyperactivity disorder (ADHD) is defined as a disorder of impaired attention and/or behavioral control. Studies suggest that the condition can dispose individuals to a higher risk of automobile accidents. ADHD symptoms respond to pharmacotherapy in a majority of uncomplicated cases. Evidence on how pharmacotherapies for ADHD impact driving behavior or outcomes could allow clinicians to support on-road safety rationally. We therefore undertook a review to identify the evidence base to date indicating positive or negative effects of pharmacotherapies on driving behavior in individuals with ADHD...
October 19, 2017: CNS Drugs
https://www.readbyqxmd.com/read/29051177/high-intelligence-and-the-risk-of-adhd-and-other-psychopathology
#7
Nanda Rommelse, Kevin Antshel, Stijn Smeets, Corina Greven, Lianne Hoogeveen, Stephen V Faraone, Catharina A Hartman
BackgroundHigh intelligence may be associated with positive (adaptive, desired) outcomes, but may also come with disadvantages.AimsTo contribute empirically to the debate concerning whether a trade-off in IQ scores exists in relation to attention-deficit hyperactivity disorder (ADHD) and related problems, suggesting that high intelligence - like low intelligence - increases the risk of ADHD.MethodCurves of the relation between IQ score and ADHD problems were fitted to questionnaire data (parent, teacher, self-report) in a population-based study of 2221 children and adolescents aged 10-12 years...
October 19, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29050518/naming-speed-as-a-predictive-diagnostic-measure-in-reading-and-attentional-problems
#8
Débora Areces, Trinidad García, Paloma González-Castro, David Alvarez-García, Celestino Rodríguez
This study aimed to describe and compare naming speed abilities in children diagnosed with either Reading Learning Difficulties (RLD) or Attention Deficit/Hyperactivity Disorder (ADHD), or comorbidity for both (ADHD+RLD). To examine the explanatory power of naming speed and ADHD symptomatology in predicting group associations (while controlling for gender and age), the "Rapid Automatized Naming and Rapid Alternating Stimulus Tests" (RAN/RAS) were utilized. A sample of 101 children (age range = 5-16 years) was divided into four groups: RLD (n = 14), ADHD (n = 28), comorbid (n = 19), and control (n = 40)...
October 20, 2017: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/29050505/late-onset-adhd-reconsidered-with-comprehensive-repeated-assessments-between-ages-10-and-25
#9
Margaret H Sibley, Luis A Rohde, James M Swanson, Lily T Hechtman, Brooke S G Molina, John T Mitchell, L Eugene Arnold, Arthur Caye, Traci M Kennedy, Arunima Roy, Annamarie Stehli
OBJECTIVE: Adolescents and young adults without childhood attention deficit hyperactivity disorder (ADHD) often present to clinics seeking stimulant medication for late-onset ADHD symptoms. Recent birth-cohort studies support the notion of late-onset ADHD, but these investigations are limited by relying on screening instruments to assess ADHD, not considering alternative causes of symptoms, or failing to obtain complete psychiatric histories. The authors address these limitations by examining psychiatric assessments administered longitudinally to the local normative comparison group of the Multimodal Treatment Study of ADHD...
October 20, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/29049706/childhood-adhd-symptoms-and-future-illicit-drug-use-the-role-of-adolescent-cigarette-use
#10
Chien-Ti Lee, Francis J McClernon, Scott H Kollins, Bernard F Fuemmeler
The aim of this study is to understand how early cigarette use might predict subsequent illicit drug use, especially among individuals with attention-deficit hyperactivity disorder (ADHD) symptoms during childhood. Data were drawn from the National Longitudinal Study of Adolescent Health (Waves I-IV). The analysis sample involves participants who had not used illicit drugs at Wave I, with no missing responses for studied predictors ( N  = 7,332). Smoking status at Wave I (ever regular vs. never regular) and childhood ADHD symptoms predicted subsequent illicit drug use at Waves II to IV...
July 17, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29049598/cortical-and-sensory-causes-of-individual-differences-in-selective-attention-ability-among-listeners-with-normal-hearing-thresholds
#11
Barbara Shinn-Cunningham
Purpose: This review provides clinicians with an overview of recent findings relevant to understanding why listeners with normal hearing thresholds (NHTs) sometimes suffer from communication difficulties in noisy settings. Method: The results from neuroscience and psychoacoustics are reviewed. Results: In noisy settings, listeners focus their attention by engaging cortical brain networks to suppress unimportant sounds; they then can analyze and understand an important sound, such as speech, amidst competing sounds...
October 17, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29049225/factors-related-to-pediatric-obstructive-sleep-apnea-hypopnea-syndrome-in-children-with-attention-deficit-hyperactivity-disorder-in-different-age-groups
#12
Jiali Wu, Meizhen Gu, Shumei Chen, Wei Chen, Kun Ni, Hongming Xu, Xiaoyan Li
This study aimed to retrospectively investigate the factors related to pediatric obstructive sleep apnea-hypopnea syndrome (OSAHS) with attention deficit hyperactivity disorder (ADHD) in children younger than 6 years and those older than 6 years.A total of 437 children who were hospitalized due to OSAHS between January 2014 and December 2014 were retrospectively reviewed. The children were further divided into OSAHS group and OSAHS + ADHD group. The general characteristics, OSA-18 quality of life, intention-hyperactivity score, and polysomnographic parameters (apnea-hypopnea index and the lowest oxygen saturation) were collected and compared between groups...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29049077/persistence-and-adherence-to-psychostimulants-and-psychological-well-being-up-to-3-years-after-specialized-treatment-of-adult-attention-deficit-hyperactivity-disorder-a-naturalistic-follow-up-study
#13
Denise Bijlenga, Semahat Kulcu, Trevor van Gellecum, Zeynep Eryigit, J J Sandra Kooij
BACKGROUND: Little is known about the long-term persistence and adherence of psychostimulant use in adults with attention-deficit/hyperactivity disorder (ADHD) and its relationship to their psychological well-being. METHODS: The persistence and adherence to psychostimulants and psychological well-being were examined in adults with ADHD in a naturalistic follow-up, starting directly after discharge from their specialized treatment of ADHD at an outpatient ADHD clinic...
October 19, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29048550/altered-neurophysiological-processing-of-auditory-attention-in-preschool-children-with-sickle-cell-disease
#14
Michelle Downes, Fenella J Kirkham, Paul T Telfer, Michelle de Haan
Objective: Sickle cell disease (SCD) is a genetic red blood cell disorder that often leads to stroke and executive dysfunction in school-age children and adults. This study aimed to characterize the development of the neural correlates of selective attention, an early component of executive function, in preschool children with SCD. Methods: Auditory event-related potentials (ERPs) were recorded while children attended to a story stream in one ear and ignored a second story in the other ear interchangeably...
September 18, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29048312/adhd-symptoms-and-peer-problems-mediation-of-executive-function-and-theory-of-mind
#15
Carmen Berenguer Forner, Belén Roselló Miranda, Inmaculada Baixauli Fortea, Rosa García Castellar, Carla Colomer Diago, Ana Miranda Casas
BACKGROUND: The social maladjustment suffered by many children with attention deficit hyperactivity disorder (ADHD) is maintained over time, increasing the risk of subsequent adverse outcomes. The objectives of the study were to explore the mechanisms that operate between ADHD symptoms and social problems with peers, considering the mediation of FE and ToM. METHOD: 35 children with ADHD and 37 with typical development matched in age and IQ were compared. Parents assessed ToM skills and relationships with peers, and teachers provided EF ratings...
November 2017: Psicothema
https://www.readbyqxmd.com/read/29046989/epilepsy-and-psychiatric-comorbidities-drug-selection
#16
REVIEW
Marco Mula
Purpose of review The pharmacological treatment of patients with epilepsy and psychiatric comorbidities may sometimes represent a therapeutic challenge. This review is focused on the pharmacological management of patients with epilepsy and psychiatric problems in terms of rationalization of the antiepileptic drug (AED) treatment and the pharmacological management of the most clinically relevant psychiatric comorbidities, namely mood and anxiety disorders, psychoses, and attention deficit hyperactivity disorder (ADHD)...
October 19, 2017: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/29046136/phenotype-development-in-adolescents-with-tourette-syndrome-a-large-clinical-longitudinal-study
#17
Camilla Groth, Nanette Mol Debes, Liselotte Skov
Tourette syndrome (TS) is a neurodevelopmental disorder characterized by frequent comorbidities and a wide spectrum of phenotype presentations. This study aimed to describe the development of phenotypes in TS and tic-related impairment in a large longitudinal study of 226 children and adolescents followed up after 6 years. The participants were clinically examined to assess tic severity and impairment, obsessive compulsive disorder (OCD), and attention-deficit/hyperactivity disorder (ADHD). The development in phenotypes changed toward less comorbidity with 40% TS-only (no OCD or ADHD) (TS without OCD or ADHD) at baseline and 55% at follow-up...
November 2017: Journal of Child Neurology
https://www.readbyqxmd.com/read/29046039/topical-review-transitional-services-for-teens-and-young-adults-with-attention-deficit-hyperactivity-disorder-a-process-map-and-proposed-model-to-overcoming-barriers-to-care
#18
Jason M Fogler, David Burke, James Lynch, William J Barbaresi, Eugenia Chan
Objective: To provide a topical review of the personal vulnerabilities and systemic barriers facing transitional age young adults with attention-deficit hyperactivity disorder (ADHD), followed by a proposed model for overcoming those barriers. Methods: Drawing from a growing, but limited, literature on the topic, we outline a process map for identifying and troubleshooting barriers to care in this at-risk population. Results: Young adults with ADHD frequently lack the organizational skills, time management, prioritization, and persistence to manage their health care at an expected level of adult independence...
November 1, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29045260/encopresis-plus
#19
DePorres Cormier, Marie Reilly, Amy Young, Marilyn Augustyn
Dexter is a 12-year-old boy who presents with his maternal grandmother for follow-up to primary care for secondary encopresis. Dexter presented, 18 months ago, with a 3-month history of secondary encopresis. At that time, a comprehensive assessment revealed functional constipation resulting in encopresis. Dexter's symptoms resolved with a combination of medication management and behavioral strategies; laxatives were discontinued 12 months ago.Dexter's grandmother reports that for the past 6 months, her grandson developed encopresis once again...
October 17, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29044556/the-social-play-social-skills-and-parent-child-relationships-of-children-with-adhd-12%C3%A2-months-following-a-rct-of-a-play-based-intervention
#20
Gabrielle Barnes, Sarah Wilkes-Gillan, Anita Bundy, Reinie Cordier
BACKGROUND/AIM: There is an urgent need to investigate the long-term impact of social skill interventions for children with attention deficit hyperactivity disorder (ADHD). Interventions targeting the social skills of children with ADHD have limited short-term effectiveness and rarely investigate the long-term impact. Furthermore, these interventions are most frequently conducted in the clinic setting, without including the child's natural settings and interactants, such as their regular playmates and parents...
October 18, 2017: Australian Occupational Therapy Journal
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