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https://www.readbyqxmd.com/read/27864935/adenoid-cystic-carcinoma-of-the-trachea-resulting-in-fatal-asphyxia
#1
Butch Huston, Victor Froloff, Kelly Mills, Michael McGee
Primary malignant tumors of the trachea are uncommon. The authors report a case of a 72-year-old female who died from asphyxia due to an undiagnosed obstructing adenoid cystic carcinoma of the trachea. The decedent became unresponsive while eating cereal and was pronounced upon arrival at the local hospital. The autopsy revealed a near occlusive tumor mass just superior to the bifurcation of the distal trachea. There was no evidence of aspiration. The death was the result of asphyxia due to obstruction of the trachea by an adenoid cystic carcinoma...
November 16, 2016: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/27729501/working-conditions-occupational-injuries-and-health-among-filipino-fish-processing-workers-in-dutch-harbor-alaska
#2
Gabriel Macasiray Garcia, Butch de Castro
This study explored how unique environmental conditions in Alaska influenced occupational health and safety for Filipino fish processing workers, many of whom migrated from warm locations (e.g., the Philippines, California, and Nevada). In-depth interviews were conducted with 26 Filipino workers in one commercial fish processing company in Dutch Harbor. Results indicated that cold weather interferes with workers' job performance, increasing their risk for injury and illness, whereas the community's isolation and rural nature causes loneliness and boredom, resulting in more high-risk behaviors...
October 11, 2016: Workplace Health & Safety
https://www.readbyqxmd.com/read/27691947/pharmacokinetic-evaluation-of-meloxicam-after-intravenous-and-intramuscular-administration-in-nile-tilapia-oreochromis-niloticus
#3
Daniel V Fredholm, Natalie D Mylniczenko, Butch KuKanich
Critically evaluating the pharmacokinetic behavior of a drug in the body provides crucial information about how to effectively treat a patient. Pharmacokinetic studies that exist in fish have primarily focused on drugs used to treat infectious disease, with minimal attention given to analgesic drugs. The objective of this study was to determine the pharmacokinetics of meloxicam (1 mg/kg) in Nile tilapia ( Oreochromis niloticus ) (n = 12). A single dose of meloxicam was administered either i.v. or i.m. Blood samples were obtained at predetermined times after drug injection...
September 2016: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/27650796/spin-orbit-coupled-molecular-quantum-magnetism-realized-in-inorganic-solid
#4
Sang-Youn Park, S-H Do, K-Y Choi, J-H Kang, Dongjin Jang, B Schmidt, Manuel Brando, B-H Kim, D-H Kim, N P Butch, Seongsu Lee, J-H Park, Sungdae Ji
Molecular quantum magnetism involving an isolated spin state is of particular interest due to the characteristic quantum phenomena underlying spin qubits or molecular spintronics for quantum information devices, as demonstrated in magnetic metal-organic molecular systems, the so-called molecular magnets. Here we report the molecular quantum magnetism realized in an inorganic solid Ba3Yb2Zn5O11 with spin-orbit coupled pseudospin-½ Yb(3+) ions. The magnetization represents the magnetic quantum values of an isolated Yb4 tetrahedron with a total (pseudo)spin 0, 1 and 2...
September 21, 2016: Nature Communications
https://www.readbyqxmd.com/read/27617163/macrophage-inflammatory-protein-3-alpha-mip-3%C3%AE-ccl20-in-hiv-1-infected-individuals
#5
Najib Aziz, Roger Detels, L Cindy Chang, Anthony W Butch
OBJECTIVE: Uncontrolled HIV infection progresses to the depletion of systemic and mucosal CD4 and AIDS. Early HIV infection may be associated with increases in the concentration of MIP-3α in the blood and gut fluids. MIP-3α/CCL20 is the only chemokine known to interact with CCR6 receptors which are expressed on immature dendritic cells and both effector and memory CD8(+) and CD4(+) T cells. The role and prognostic value of blood levels of MIP-3α in HIV-infected individuals has yet to be described...
July 2016: Journal of AIDS & Clinical Research
https://www.readbyqxmd.com/read/27594536/urinary-human-chorionic-gonadotropin-isoform-concentrations-in-doping-control-samples
#6
Anthony W Butch, Getachew A Woldemariam
Anti-doping laboratories routinely use immunoassays to measure urinary concentrations of human chorionic gonadotropin (hCG). To minimize immunoassay differences and false positive screen results from inactive isoforms (free β-subunit (hCGβ), β-subunit core fragment (hCGβcf)) laboratories now use intact hCG instead of total hCG immunoassays to measure hCG. To determine the distribution of hCG isoforms in urine, we determined the concentrations of intact hCG, hCGβ, and hCGβcf in male urine samples based on immunoassay total hCG concentrations using a sequential immunoextraction and a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method...
November 2016: Drug Testing and Analysis
https://www.readbyqxmd.com/read/27552491/exploring-post-treatment-reversion-of-antimicrobial-resistance-in-enteric-bacteria-of-food-animals-as-a-resistance-mitigation-strategy
#7
Victoriya V Volkova, Butch KuKanich, Jim E Riviere
Antimicrobial drug use in food animals is associated with an elevation in relative abundance of bacteria resistant to the drug among the animal enteric bacteria. Some of these bacteria are potential foodborne pathogens. Evidence suggests that at least in the enteric nontype-specific Escherichia coli, after treatment the resistance abundance reverts to the background pre-treatment levels, without further interventions. We hypothesize that it is possible to define the distribution of the time period after treatment within which resistance to the administered drug, and possibly other drugs in case of coselection, in fecal bacteria of the treated animals returns to the background pre-treatment levels...
August 23, 2016: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/27504239/contextual-determinants-on-the-meaning-of-the-n-word
#8
Keith Allan
Use of the word nigger is very often castigated as slurring the referent, but this ignores the context of use. For many people the word itself is a slur no matter what the context, and such people argue for its eradication from the English language. Eradicationists confuse the form of the word with its frequent use as a slur that discredits, slights, smears, stains, besmirches people of black African descent. In this paper I discuss several occurrences of the N word in Quentin Tarantino's film 'Pulp Fiction'...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27474776/evaluation-of-2-batched-pretreatment-systems-for-the-measurement-of-whole-blood-tacrolimus-on-the-architect-immunoassay-analyzer
#9
Sami Albeiroti, Michael O Alberti, Vincent Buggs, Gordon Swartz, Anthony W Butch, Julia C Drees, Kathleen A Kelly
BACKGROUND: Measurement of tacrolimus using the ARCHITECT immunoassay analyzer requires a manual extraction step that puts clinical laboratory workers at risk for ergonomic injury. Therefore, we developed 2 batched extraction systems for tacrolimus measurement on the ARCHITECT analyzer and describe their features herein. METHODS: Two batched extraction methods were developed at 2 different laboratories. The batched extraction methods allow processing of at least 20 specimens at a time...
November 2016: Laboratory Medicine
https://www.readbyqxmd.com/read/27443234/the-abiotic-chemistry-of-thiolated-acetate-derivatives-and-the-origin-of-life
#10
Kuhan Chandru, Alexis Gilbert, Christopher Butch, Masashi Aono, H James Cleaves
Thioesters and thioacetic acid (TAA) have been invoked as key reagents for the origin of life as activated forms of acetate analogous to acetyl-CoA. These species could have served as high-energy group-transfer reagents and allowed carbon insertions to form higher molecular weight compounds such as pyruvate. The apparent antiquity of the Wood-Ljungdahl CO2 fixation pathway and its presence in organisms which inhabit hydrothermal (HT) environments has also led to suggestions that there may be a connection between the abiotic chemistry of compounds similar to TAA and the origins of metabolism...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27208752/stability-of-cytokines-chemokines-and-soluble-activation-markers-in-unprocessed-blood-stored-under-different-conditions
#11
Najib Aziz, Roger Detels, Joshua J Quint, Qian Li, David Gjertson, Anthony W Butch
BACKGROUND: Biomarkers such as cytokines, chemokines, and soluble activation markers can be unstable when processing of blood is delayed. The stability of various biomarkers in serum and plasma was investigated when unprocessed blood samples were stored for up to 24h at room and refrigerator temperature. METHODS: Blood was collected from 16 healthy volunteers. Unprocessed serum, EDTA and heparinized blood was stored at room (20-25°C) and refrigerator temperature (4-8°C) for 0...
August 2016: Cytokine
https://www.readbyqxmd.com/read/27142002/intersections-and-evolution-of-butch-trans-categories-in-puerto-rico-needs-and-barriers-of-an-invisible-population
#12
Alíxida G Ramos-Pibernus, Sheilla L Rodríguez-Madera, Mark Padilla, Nelson Varas-Díaz, Ricardo Vargas Molina
Public health research among transgender populations globally has primarily focused on HIV/AIDS. However, trans men remain outside of this conceptual framework, with distinct but overlapping social contexts and needs. In Puerto Rico (PR), the trans men population has remained largely hidden within the 'butch' lesbian community. The objective of this article is to document the identity construction of trans men and 'buchas' (local term to refer to butch lesbians) in PR and its relation to their bodily practices and overall health...
August 2016: Global Public Health
https://www.readbyqxmd.com/read/27127976/pressure-resistant-intermediate-valence-in-the-kondo-insulator-smb_-6
#13
Nicholas P Butch, Johnpierre Paglione, Paul Chow, Yuming Xiao, Chris A Marianetti, Corwin H Booth, Jason R Jeffries
Resonant x-ray emission spectroscopy was used to determine the pressure dependence of the f-electron occupancy in the Kondo insulator SmB_{6}. Applied pressure reduces the f occupancy, but surprisingly, the material maintains a significant divalent character up to a pressure of at least 35 GPa. Thus, the closure of the resistive activation energy gap and onset of magnetic order are not driven by stabilization of an integer valent state. Over the entire pressure range, the material maintains a remarkably stable intermediate valence that can in principle support a nontrivial band structure...
April 15, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27088740/pharmacokinetics-of-a-single-dose-of-oral-and-subcutaneous-meloxicam-in-caribbean-flamingos-phoenicopterus-ruber-ruber
#14
Dana M Lindemann, James W Carpenter, Butch KuKanich
To determine the pharmacokinetics of meloxicam in Caribbean flamingos ( Phoenicopterus ruber ruber), a pilot study was performed first, followed by a complete pharmacokinetic study. Four healthy birds were divided into 2 groups and administered 1 mg/kg of either oral (n = 2) or subcutaneous (n = 2) meloxicam. Plasma meloxicam concentrations were determined with liquid chromatography-mass spectrometry. Based on the pilot study results, 12 healthy birds were assigned into 2 groups and administered either 3 mg/kg PO (n = 6) or 1...
March 2016: Journal of Avian Medicine and Surgery
https://www.readbyqxmd.com/read/27087966/enhancing-both-ct-imaging-and-natural-killer-cell-mediated-cancer-cell-killing-by-a-gd2-targeting-nanoconstruct
#15
Peifu Jiao, Mario Otto, Qiaohong Geng, Chencan Li, Faming Li, Elizabeth R Butch, Scott E Snyder, Hongyu Zhou, Bing Yan
Although nanomaterials have been widely investigated for drug delivery, imaging and immunotherapy, their potential roles in triggering innate cellular immune responses while simultaneously serving as imaging enhancer remain unexplored. In this work, gold nanoparticles (GNPs) conjugated to the tumor-targeting anti-GD2 antibody hu14.18K322A, namely HGNPs, were designed and synthesized to specifically enhance computerized tomography (CT) imaging contrast and to stimulate the attack of neuroblastoma and melanoma cells by natural killer (NK) cells...
January 20, 2016: Journal of Materials Chemistry. B, Materials for Biology and Medicine
https://www.readbyqxmd.com/read/26998755/advantages-and-limitations-of-androgen-receptor-based-methods-for-detecting-anabolic-androgenic-steroid-abuse-as-performance-enhancing-drugs
#16
Kathy Bailey, Tahmineh Yazdi, Umesh Masharani, Blake Tyrrell, Anthony Butch, Fred Schaufele
Testosterone (T) and related androgens are performance enhancing drugs (PEDs) abused by some athletes to gain competitive advantage. To monitor unauthorized androgen abuse, doping control programs use mass spectrometry (MS) to detect androgens, synthetic anabolic-androgenic steroids (AASs) and their metabolites in an athlete's urine. AASs of unknown composition will not be detected by these procedures. Since AASs achieve their anabolic effects by activating the Androgen Receptor (AR), cell-based bioassays that measure the effect of a urine sample on AR activity are under investigation as complementary, pan-androgen detection methods...
2016: PloS One
https://www.readbyqxmd.com/read/26919596/pharmacokinetics-of-long-acting-cefovecin-in-copper-rockfish-sebastes-caurinus
#17
Kathryn E Seeley, Karen N Wolf, Melissa A Bishop, Megan Turnquist, Butch KuKanich
OBJECTIVE: To assess the pharmacokinetic properties of cefovecin in a cold-water teleost species. ANIMALS: 10 healthy adult copper rockfish (Sebastes caurinus), sex unknown. PROCEDURES: Cefovecin (16 mg/kg) was administered SC to the rockfish. Blood samples were collected at predetermined points for measurement of plasma cefovecin concentrations (3 samples/fish). Plasma cefovecin concentrations were measured via liquid chromatography with mass spectrometry...
March 2016: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/26701771/she-s-always-a-woman-butch-lesbian-trans-women-in-the-lesbian-community
#18
Hannah Rossiter
While the visibility and acceptance of trans women have grown globally in recent years, this progress has primarily been within a traditional, heteronormative narrative. But a growing number of trans women identify as butch lesbians and challenge this heteronormative narrative. The existence of butch trans women has created a debate on where they fit within queer and lesbian communities and how their gender performance fits within traditional butch/femme understandings of lesbian or queer relationships. This article seeks to explore the intersections of gender identity and sexual orientation that butch trans women experience when they engage with lesbian and trans communities...
2016: Journal of Lesbian Studies
https://www.readbyqxmd.com/read/26684503/a-strategy-for-origins-of-life-research
#19
Caleb Scharf, Nathaniel Virgo, H James Cleaves, Masashi Aono, Nathanael Aubert-Kato, Arsev Aydinoglu, Ana Barahona, Laura M Barge, Steven A Benner, Martin Biehl, Ramon Brasser, Christopher J Butch, Kuhan Chandru, Leroy Cronin, Sebastian Danielache, Jakob Fischer, John Hernlund, Piet Hut, Takashi Ikegami, Jun Kimura, Kensei Kobayashi, Carlos Mariscal, Shawn McGlynn, Brice Menard, Norman Packard, Robert Pascal, Juli Pereto, Sudha Rajamani, Lana Sinapayen, Eric Smith, Christopher Switzer, Ken Takai, Feng Tian, Yuichiro Ueno, Mary Voytek, Olaf Witkowski, Hikaru Yabuta
Contents 1. Introduction 1.1. A workshop and this document 1.2. Framing origins of life science 1.2.1. What do we mean by the origins of life (OoL)? 1.2.2. Defining life 1.2.3. How should we characterize approaches to OoL science? 1.2.4. One path to life or many? 2. A Strategy for Origins of Life Research 2.1. Outcomes-key questions and investigations 2.1.1. Domain 1: Theory 2.1.2. Domain 2: Practice 2.1.3. Domain 3: Process 2.1.4. Domain 4: Future studies 2.2. EON Roadmap 2.3. Relationship to NASA Astrobiology Roadmap and Strategy documents and the European AstRoMap   Appendix I   Appendix II   Supplementary Materials  References...
December 2015: Astrobiology
https://www.readbyqxmd.com/read/26660193/detection-of-stimulants-and-narcotics-by-liquid-chromatography-tandem-mass-spectrometry-and-gas-chromatography-mass-spectrometry-for-sports-doping-control
#20
Brian D Ahrens, Yulia Kucherova, Anthony W Butch
Sports drug testing laboratories are required to detect several classes of compounds that are prohibited at all times, which include anabolic agents, peptide hormones, growth factors, beta-2 agonists, hormones and metabolic modulators, and diuretics/masking agents. Other classes of compounds such as stimulants, narcotics, cannabinoids, and glucocorticoids are also prohibited, but only when an athlete is in competition. A single class of compounds can contain a large number of prohibited substances and all of the compounds should be detected by the testing procedure...
2016: Methods in Molecular Biology
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